Result of FASTA (omim) for
pF1KSDA1348
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1348, 529 aa
1>>>pF1KSDA1348 529 - 529 aa - 529 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6855+/-0.000418; mu= 16.0852+/- 0.026
mean_var=70.3604+/-13.866, 0's: 0 Z-trim(111.4): 71 B-trim: 0 in 0/50
Lambda= 0.152901
statistics sampled from 19868 (19939) to 19868 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.234), width: 16
Scan time: 9.390
The best scores are: opt bits E(85289)
NP_001316859 (OMIM: 615499) [Pyruvate dehydrogenas ( 529) 3545 791.6 0
NP_001316862 (OMIM: 615499) [Pyruvate dehydrogenas ( 529) 3545 791.6 0
NP_001316857 (OMIM: 615499) [Pyruvate dehydrogenas ( 529) 3545 791.6 0
NP_001316858 (OMIM: 615499) [Pyruvate dehydrogenas ( 529) 3545 791.6 0
NP_001316863 (OMIM: 615499) [Pyruvate dehydrogenas ( 529) 3545 791.6 0
NP_001316860 (OMIM: 615499) [Pyruvate dehydrogenas ( 529) 3545 791.6 0
NP_001316861 (OMIM: 615499) [Pyruvate dehydrogenas ( 529) 3545 791.6 0
NP_065837 (OMIM: 615499) [Pyruvate dehydrogenase [ ( 529) 3545 791.6 0
NP_060914 (OMIM: 605993,608782) pyruvate dehyrogen ( 537) 1715 387.9 4e-107
XP_011515438 (OMIM: 605993,608782) PREDICTED: pyru ( 537) 1715 387.9 4e-107
NP_001155253 (OMIM: 605993,608782) pyruvate dehyro ( 537) 1715 387.9 4e-107
XP_011515437 (OMIM: 605993,608782) PREDICTED: pyru ( 555) 1715 387.9 4.2e-107
NP_001155252 (OMIM: 605993,608782) pyruvate dehyro ( 562) 1715 387.9 4.2e-107
NP_001155251 (OMIM: 605993,608782) pyruvate dehyro ( 562) 1715 387.9 4.2e-107
XP_016869077 (OMIM: 605993,608782) PREDICTED: pyru ( 591) 1715 387.9 4.4e-107
XP_016869076 (OMIM: 605993,608782) PREDICTED: pyru ( 596) 1715 387.9 4.4e-107
NP_003611 (OMIM: 114480,605100) protein phosphatas ( 605) 190 51.5 8.3e-06
XP_011536881 (OMIM: 616016) PREDICTED: protein pho ( 263) 150 42.6 0.0018
XP_011536880 (OMIM: 616016) PREDICTED: protein pho ( 476) 150 42.7 0.003
NP_065751 (OMIM: 616016) protein phosphatase 1H [H ( 514) 150 42.7 0.0033
>>NP_001316859 (OMIM: 615499) [Pyruvate dehydrogenase [a (529 aa)
initn: 3545 init1: 3545 opt: 3545 Z-score: 4225.9 bits: 791.6 E(85289): 0
Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)
10 20 30 40 50 60
pF1KSD MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
430 440 450 460 470 480
490 500 510 520
pF1KSD NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
490 500 510 520
>>NP_001316862 (OMIM: 615499) [Pyruvate dehydrogenase [a (529 aa)
initn: 3545 init1: 3545 opt: 3545 Z-score: 4225.9 bits: 791.6 E(85289): 0
Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)
10 20 30 40 50 60
pF1KSD MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
430 440 450 460 470 480
490 500 510 520
pF1KSD NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
490 500 510 520
>>NP_001316857 (OMIM: 615499) [Pyruvate dehydrogenase [a (529 aa)
initn: 3545 init1: 3545 opt: 3545 Z-score: 4225.9 bits: 791.6 E(85289): 0
Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)
10 20 30 40 50 60
pF1KSD MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
430 440 450 460 470 480
490 500 510 520
pF1KSD NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
490 500 510 520
>>NP_001316858 (OMIM: 615499) [Pyruvate dehydrogenase [a (529 aa)
initn: 3545 init1: 3545 opt: 3545 Z-score: 4225.9 bits: 791.6 E(85289): 0
Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)
10 20 30 40 50 60
pF1KSD MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
430 440 450 460 470 480
490 500 510 520
pF1KSD NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
490 500 510 520
>>NP_001316863 (OMIM: 615499) [Pyruvate dehydrogenase [a (529 aa)
initn: 3545 init1: 3545 opt: 3545 Z-score: 4225.9 bits: 791.6 E(85289): 0
Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)
10 20 30 40 50 60
pF1KSD MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
430 440 450 460 470 480
490 500 510 520
pF1KSD NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
490 500 510 520
>>NP_001316860 (OMIM: 615499) [Pyruvate dehydrogenase [a (529 aa)
initn: 3545 init1: 3545 opt: 3545 Z-score: 4225.9 bits: 791.6 E(85289): 0
Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)
10 20 30 40 50 60
pF1KSD MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
430 440 450 460 470 480
490 500 510 520
pF1KSD NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
490 500 510 520
>>NP_001316861 (OMIM: 615499) [Pyruvate dehydrogenase [a (529 aa)
initn: 3545 init1: 3545 opt: 3545 Z-score: 4225.9 bits: 791.6 E(85289): 0
Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)
10 20 30 40 50 60
pF1KSD MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
430 440 450 460 470 480
490 500 510 520
pF1KSD NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
490 500 510 520
>>NP_065837 (OMIM: 615499) [Pyruvate dehydrogenase [acet (529 aa)
initn: 3545 init1: 3545 opt: 3545 Z-score: 4225.9 bits: 791.6 E(85289): 0
Smith-Waterman score: 3545; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)
10 20 30 40 50 60
pF1KSD MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MSSTVSYWILNSTRNSIATLQGGRRLYSRYVSNRNKLKWRLFSRVPPTLNSSPCGGFTLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KAYRHTSTEEDDFHLQLSPEQINEVLRAGETTHKILDLESRVPNSVLRFESNQLAANSPV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EDRRGVASCLQTNGLMFGIFDGHGGHACAQAVSERLFYYVAVSLMSHQTLEHMEGAMESM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KPLLPILHWLKHPGDSIYKDVTSVHLDHLRVYWQELLDLHMEMGLSIEEALMYSFQRLDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DISLEIQAPLEDEVTRNLSLQVAFSGATACMAHVDGIHLHVANAGDCRAILGVQEDNGMW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SCLPLTRDHNAWNQAELSRLKREHPESEDRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RSILERGFNTEALNIYQFTPPHYYTPPYLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EDVVRLVVGHLAEADWHKTDLAQRPANLGLMQSLLLQRKASGLHEADQNAATRLIRHAIG
430 440 450 460 470 480
490 500 510 520
pF1KSD NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NNEYGEMEAERLAAMLTLPEDLARMYRDDITVTVVYFNSESIGAYYKGG
490 500 510 520
>>NP_060914 (OMIM: 605993,608782) pyruvate dehyrogenase (537 aa)
initn: 1357 init1: 586 opt: 1715 Z-score: 2044.1 bits: 387.9 E(85289): 4e-107
Smith-Waterman score: 1715; 54.4% identity (79.9% similar) in 472 aa overlap (61-525:67-533)
40 50 60 70 80 90
pF1KSD VSNRNKLKWRLFSRVPPTLNSSPCGGFTLCKAYRHTSTEEDDFHLQLSPEQINEVLRAGE
.. :..:: . .. :.: :.: .:.:.:
NP_060 SYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQ---KFYLTPPQVNSILKANE
40 50 60 70 80 90
100 110 120 130 140 150
pF1KSD TTHKILDLESRVPNSVLRFESNQLAANSPVEDRRGVASCLQTNGLMFGIFDGHGGHACAQ
. :. ..... .:.: :.:::: ::.:.::::..:.:::: :...:.::::.: ::.:
NP_060 YSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQ
100 110 120 130 140 150
160 170 180 190 200 210
pF1KSD AVSERLFYYVAVSLMSHQTLEHMEGAMESMKPLLPILHWLKHPGDSIYKDVTSVHLDHLR
:::::::::.::::. :.:: ..:.:.:: . :::::.: :::.: . :........ ::
NP_060 AVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLR
160 170 180 190 200 210
220 230 240 250 260
pF1KSD VYWQELLDLHM--EMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGAT
.:::::.::. ....:::. .:.:::.::::: :. . : :.:::::::
NP_060 TYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGAT
220 230 240 250 260 270
270 280 290 300 310 320
pF1KSD ACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREHPESE
::.:::::. :::::.:: ::.:::::..: :: . :. :::: :. :: ::: :::.::
NP_060 ACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSE
280 290 300 310 320 330
330 340 350 360 370 380
pF1KSD DRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIY-QFTPPHYYTPP
.... .:::::.:.: ::::::..::: .::. ..: : . : : .: ::.:.:::
NP_060 AKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPP
340 350 360 370 380 390
390 400 410 420 430 440
pF1KSD YLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTDLA--QRP
:::::::::::::::::::::::.::::. . .:::: .::. . :. .:
NP_060 YLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVR-IVGEYLTGMHHQQPIAVGGYK
400 410 420 430 440 450
450 460 470 480 490 500
pF1KSD ANLGLMQSLLLQR--KASGLHEADQNAATRLIRHAIGNNEYGEMEAERLAAMLTLPEDLA
..:: :..:: .: : :.. : ::::::.:::::.::::.: .. :::. ::.:::.::
NP_060 VTLGQMHGLLTERRTKMSSVFE-DQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELA
460 470 480 490 500 510
510 520
pF1KSD RMYRDDITVTVVYFNSESIGAYYKGG
::::::::. :: :::. .:::
NP_060 RMYRDDITIIVVQFNSHVVGAYQNQE
520 530
>>XP_011515438 (OMIM: 605993,608782) PREDICTED: pyruvate (537 aa)
initn: 1357 init1: 586 opt: 1715 Z-score: 2044.1 bits: 387.9 E(85289): 4e-107
Smith-Waterman score: 1715; 54.4% identity (79.9% similar) in 472 aa overlap (61-525:67-533)
40 50 60 70 80 90
pF1KSD VSNRNKLKWRLFSRVPPTLNSSPCGGFTLCKAYRHTSTEEDDFHLQLSPEQINEVLRAGE
.. :..:: . .. :.: :.: .:.:.:
XP_011 SYIPQSRLRYTPHPAYATFCRPKENWWQYTQGRRYASTPQ---KFYLTPPQVNSILKANE
40 50 60 70 80 90
100 110 120 130 140 150
pF1KSD TTHKILDLESRVPNSVLRFESNQLAANSPVEDRRGVASCLQTNGLMFGIFDGHGGHACAQ
. :. ..... .:.: :.:::: ::.:.::::..:.:::: :...:.::::.: ::.:
XP_011 YSFKVPEFDGKNVSSILGFDSNQLPANAPIEDRRSAATCLQTRGMLLGVFDGHAGCACSQ
100 110 120 130 140 150
160 170 180 190 200 210
pF1KSD AVSERLFYYVAVSLMSHQTLEHMEGAMESMKPLLPILHWLKHPGDSIYKDVTSVHLDHLR
:::::::::.::::. :.:: ..:.:.:: . :::::.: :::.: . :........ ::
XP_011 AVSERLFYYIAVSLLPHETLLEIENAVESGRALLPILQWHKHPNDYFSKEASKLYFNSLR
160 170 180 190 200 210
220 230 240 250 260
pF1KSD VYWQELLDLHM--EMGLSIEEALMYSFQRLDSDISLEIQAPLEDEVTRNLSLQVAFSGAT
.:::::.::. ....:::. .:.:::.::::: :. . : :.:::::::
XP_011 TYWQELIDLNTGESTDIDVKEALINAFKRLDNDISLEAQVGDPNSFLNYLVLRVAFSGAT
220 230 240 250 260 270
270 280 290 300 310 320
pF1KSD ACMAHVDGIHLHVANAGDCRAILGVQEDNGMWSCLPLTRDHNAWNQAELSRLKREHPESE
::.:::::. :::::.:: ::.:::::..: :: . :. :::: :. :: ::: :::.::
XP_011 ACVAHVDGVDLHVANTGDSRAMLGVQEEDGSWSAVTLSNDHNAQNERELERLKLEHPKSE
280 290 300 310 320 330
330 340 350 360 370 380
pF1KSD DRTIIMEDRLLGVLIPCRAFGDVQLKWSKELQRSILERGFNTEALNIY-QFTPPHYYTPP
.... .:::::.:.: ::::::..::: .::. ..: : . : : .: ::.:.:::
XP_011 AKSVVKQDRLLGLLMPFRAFGDVKFKWSIDLQKRVIESGPDQLNDNEYTKFIPPNYHTPP
340 350 360 370 380 390
390 400 410 420 430 440
pF1KSD YLTAEPEVTYHRLRPQDKFLVLASDGLWDMLSNEDVVRLVVGHLAEADWHKTDLA--QRP
:::::::::::::::::::::::.::::. . .:::: .::. . :. .:
XP_011 YLTAEPEVTYHRLRPQDKFLVLATDGLWETMHRQDVVR-IVGEYLTGMHHQQPIAVGGYK
400 410 420 430 440 450
450 460 470 480 490 500
pF1KSD ANLGLMQSLLLQR--KASGLHEADQNAATRLIRHAIGNNEYGEMEAERLAAMLTLPEDLA
..:: :..:: .: : :.. : ::::::.:::::.::::.: .. :::. ::.:::.::
XP_011 VTLGQMHGLLTERRTKMSSVFE-DQNAATHLIRHAVGNNEFGTVDHERLSKMLSLPEELA
460 470 480 490 500 510
510 520
pF1KSD RMYRDDITVTVVYFNSESIGAYYKGG
::::::::. :: :::. .:::
XP_011 RMYRDDITIIVVQFNSHVVGAYQNQE
520 530
529 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 05:55:28 2016 done: Thu Nov 3 05:55:30 2016
Total Scan time: 9.390 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]