FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1165, 242 aa
  1>>>pF1KSDA1165 242 - 242 aa - 242 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.3045+/-0.000304; mu= 0.5561+/- 0.019
 mean_var=137.2161+/-27.780, 0's: 0 Z-trim(121.6): 7  B-trim: 492 in 2/54
 Lambda= 0.109489
 statistics sampled from 38340 (38347) to 38340 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.45), width:  16
 Scan time:  6.990

The best scores are:                                      opt bits E(85289)
NP_061953 (OMIM: 610041) NEDD4 family-interacting  ( 336) 1642 269.9 3.8e-72
XP_006719903 (OMIM: 610041) PREDICTED: NEDD4 famil ( 335) 1625 267.3 2.4e-71
NP_001154879 (OMIM: 610041) NEDD4 family-interacti ( 316)  977 164.9 1.5e-40
NP_085048 (OMIM: 612050) NEDD4 family-interacting  ( 221)  821 140.2 2.8e-33


>>NP_061953 (OMIM: 610041) NEDD4 family-interacting prot  (336 aa)
 initn: 1642 init1: 1642 opt: 1642  Z-score: 1416.3  bits: 269.9 E(85289): 3.8e-72
Smith-Waterman score: 1642; 99.6% identity (100.0% similar) in 242 aa overlap (1-242:95-336)

                                             10        20        30
pF1KSD                               MDHHQPGTGRYQVLLNEEDNSESSAIEQPP
                                     ::::::::::::::::::::::::::::::
NP_061 AATTSSTGVAVGAEHGEDSLSRKPDPEPGRMDHHQPGTGRYQVLLNEEDNSESSAIEQPP
           70        80        90       100       110       120    

               40        50        60        70        80        90
pF1KSD TSNPAPQIVQAVSSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLP
       :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLP
          130       140       150       160       170       180    

              100       110       120       130       140       150
pF1KSD TYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFN
          190       200       210       220       230       240    

              160       170       180       190       200       210
pF1KSD WLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 WLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGL
          250       260       270       280       290       300    

              220       230       240  
pF1KSD LLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL
       ::::::::::::::::::::::::::::::::
NP_061 LLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL
          310       320       330      

>>XP_006719903 (OMIM: 610041) PREDICTED: NEDD4 family-in  (335 aa)
 initn: 1542 init1: 1542 opt: 1625  Z-score: 1401.8  bits: 267.3 E(85289): 2.4e-71
Smith-Waterman score: 1625; 99.2% identity (99.6% similar) in 242 aa overlap (1-242:95-335)

                                             10        20        30
pF1KSD                               MDHHQPGTGRYQVLLNEEDNSESSAIEQPP
                                     :::::::::::: :::::::::::::::::
XP_006 AATTSSTGVAVGAEHGEDSLSRKPDPEPGRMDHHQPGTGRYQ-LLNEEDNSESSAIEQPP
           70        80        90       100        110       120   

               40        50        60        70        80        90
pF1KSD TSNPAPQIVQAVSSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLP
       :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLP
           130       140       150       160       170       180   

              100       110       120       130       140       150
pF1KSD TYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFN
           190       200       210       220       230       240   

              160       170       180       190       200       210
pF1KSD WLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGL
           250       260       270       280       290       300   

              220       230       240  
pF1KSD LLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL
       ::::::::::::::::::::::::::::::::
XP_006 LLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL
           310       320       330     

>>NP_001154879 (OMIM: 610041) NEDD4 family-interacting p  (316 aa)
 initn: 1032 init1: 959 opt: 977  Z-score: 849.0  bits: 164.9 E(85289): 1.5e-40
Smith-Waterman score: 1440; 90.9% identity (91.7% similar) in 242 aa overlap (1-242:95-316)

                                             10        20        30
pF1KSD                               MDHHQPGTGRYQVLLNEEDNSESSAIEQPP
                                     ::::::::::::::::::::::::::::::
NP_001 AATTSSTGVAVGAEHGEDSLSRKPDPEPGRMDHHQPGTGRYQVLLNEEDNSESSAIEQPP
           70        80        90       100       110       120    

               40        50        60        70        80        90
pF1KSD TSNPAPQIVQAVSSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLP
       :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLP
          130       140       150       160       170       180    

              100       110       120       130       140       150
pF1KSD TYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
NP_001 TYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFF------
          190       200       210       220       230              

              160       170       180       190       200       210
pF1KSD WLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGL
                     .:::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------TGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGL
                    240       250       260       270       280    

              220       230       240  
pF1KSD LLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL
       ::::::::::::::::::::::::::::::::
NP_001 LLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL
          290       300       310      

>>NP_085048 (OMIM: 612050) NEDD4 family-interacting prot  (221 aa)
 initn: 904 init1: 669 opt: 821  Z-score: 718.4  bits: 140.2 E(85289): 2.8e-33
Smith-Waterman score: 821; 60.3% identity (78.9% similar) in 199 aa overlap (43-241:28-220)

             20        30        40        50        60        70  
pF1KSD VLLNEEDNSESSAIEQPPTSNPAPQIVQAVSSAPALETDSSPPPYSSITVEVPTTSDTEV
                                     :. :   . ..:::::::..:  .  : . 
NP_085    MALALAALAAVEPACGSRYQQLQNEEESGEPEQAAGDAPPPYSSISAESAAYFDYKD
                  10        20        30        40        50       

             80        90       100       110       120       130  
pF1KSD YGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLR
        . : : :: :.:::.::.:::::..:: :    .       ..:.   ::::.::::::
NP_085 ESGF-PKPPSYNVATTLPSYDEAERTKAEATIPLVPG-----RDEDFVGRDDFDDADQLR
        60         70        80        90            100       110 

            140       150       160       170       180       190  
pF1KSD VGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFT
       .::::::::.:::::.:::.:: ::::.:.. ::::::: :::::::::::::::: :: 
NP_085 IGNDGIFMLTFFMAFLFNWIGFFLSFCLTTSAAGRYGAISGFGLSLIKWILIVRFSTYFP
             120       130       140       150       160       170 

            200       210       220       230       240  
pF1KSD GYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL
       :::.:::::::.:::::.:::.:::.:: :::.: :...   ::: .:. 
NP_085 GYFDGQYWLWWVFLVLGFLLFLRGFINYAKVRKMPETFSNLPRTRVLFIY
             180       190       200       210       220 




242 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 05:11:39 2016 done: Thu Nov  3 05:11:40 2016
 Total Scan time:  6.990 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]