FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1100, 432 aa 1>>>pF1KSDA1100 432 - 432 aa - 432 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.8179+/-0.000943; mu= -4.2736+/- 0.057 mean_var=383.1905+/-78.162, 0's: 0 Z-trim(117.6): 50 B-trim: 192 in 1/54 Lambda= 0.065519 statistics sampled from 18278 (18328) to 18278 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.832), E-opt: 0.2 (0.563), width: 16 Scan time: 3.850 The best scores are: opt bits E(32554) CCDS4404.1 RNF44 gene_id:22838|Hs108|chr5 ( 432) 3131 309.3 4.7e-84 CCDS6604.1 RNF38 gene_id:152006|Hs108|chr9 ( 465) 1836 186.9 3.5e-47 CCDS6603.1 RNF38 gene_id:152006|Hs108|chr9 ( 515) 1836 187.0 3.7e-47 >>CCDS4404.1 RNF44 gene_id:22838|Hs108|chr5 (432 aa) initn: 3131 init1: 3131 opt: 3131 Z-score: 1622.6 bits: 309.3 E(32554): 4.7e-84 Smith-Waterman score: 3131; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432) 10 20 30 40 50 60 pF1KSD MRPWALAVTRWPPSAPVGQRRFSAGPGSTPGQLWGSPGLEGPLASPPARDERLPSQQPPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MRPWALAVTRWPPSAPVGQRRFSAGPGSTPGQLWGSPGLEGPLASPPARDERLPSQQPPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD RPPHLPVEERRASAPAGGSPRMLHPATQQSPFMVDLHEQVHQGPVPLSYTVTTVTTQGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 RPPHLPVEERRASAPAGGSPRMLHPATQQSPFMVDLHEQVHQGPVPLSYTVTTVTTQGFP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LPTGQHIPGCSAQQLPACSVMFSGQHYPLCCLPPPLIQACTMQQLPVPYQAYPHLISSDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LPTGQHIPGCSAQQLPACSVMFSGQHYPLCCLPPPLIQACTMQQLPVPYQAYPHLISSDH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD YILHPPPPAPPPQPTHMAPLGQFVSLQTQHPRMPLQRLDNDVDLRGDQPSLGSFTYSTSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YILHPPPPAPPPQPTHMAPLGQFVSLQTQHPRMPLQRLDNDVDLRGDQPSLGSFTYSTSA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PGPALSPSVPLHYLPHDPLHQELSFGVPYSHMMPRRLSTQRYRLQQPLPPPPPPPPPPPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 PGPALSPSVPLHYLPHDPLHQELSFGVPYSHMMPRRLSTQRYRLQQPLPPPPPPPPPPPY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD YPSFLPYFLSMLPMSPTAMGPTISLDLDVDDVEMENYEALLNLAERLGDAKPRGLTKADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YPSFLPYFLSMLPMSPTAMGPTISLDLDVDDVEMENYEALLNLAERLGDAKPRGLTKADI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD EQLPSYRFNPDSHQSEQTLCVVCFSDFEARQLLRVLPCNHEFHTKCVDKWLKANRTCPIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EQLPSYRFNPDSHQSEQTLCVVCFSDFEARQLLRVLPCNHEFHTKCVDKWLKANRTCPIC 370 380 390 400 410 420 430 pF1KSD RADASEVPREAE :::::::::::: CCDS44 RADASEVPREAE 430 >>CCDS6604.1 RNF38 gene_id:152006|Hs108|chr9 (465 aa) initn: 1381 init1: 730 opt: 1836 Z-score: 960.6 bits: 186.9 E(32554): 3.5e-47 Smith-Waterman score: 1836; 60.9% identity (79.8% similar) in 445 aa overlap (1-432:34-465) 10 20 30 pF1KSD MRPWALAVTRWPPSAPVGQRRFSAGPGSTP :::: .. .: :::. .:..::. .:: CCDS66 KSEDSPSPKRQRLSHSVFDYTSASPAPSPPMRPWEMTSNRQPPSVRPSQHHFSGERCNTP 10 20 30 40 50 60 40 50 60 70 80 pF1KSD GQLWGSPGLEGPLASPPARDERLPSQQPPSRPP---HLP------VEERRASAPAGGSPR .. :: :. .: .:: .. :. ::: .:: :: : . ::: CCDS66 ARNRRSP----PVRRQRGRRDRLSRHNSISQDENYHHLPYAQQQAIEEPRAFHPPNVSPR 70 80 90 100 110 90 100 110 120 130 pF1KSD MLHPAT---QQSPFMVDLHEQVHQGPVPLSYTVTTVTTQGFPLPTGQHIPGCSAQQLPAC .::::. ::. :::.:.:.::: ::.:::::::. .:.:: ::::::.::.::.:.: CCDS66 LLHPAAHPPQQNAVMVDIHDQLHQGTVPVSYTVTTVAPHGIPLCTGQHIPACSTQQVPGC 120 130 140 150 160 170 140 150 160 170 180 190 pF1KSD SVMFSGQHYPLCCLPPPLIQACTMQQLPVPYQAYPHLISSDHYILHPPPPAPPPQPTHMA ::.::::: :.: .:::..:::..:.::::: :.: ::::: ...::: .: .: :. CCDS66 SVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLIHPPHLSPH-HPPHLP 180 190 200 210 220 230 200 210 220 230 240 250 pF1KSD PLGQFVSLQTQHPRMPLQRLDNDVDLRGDQPSLGSFTYSTSAPGPALSPSVPLHYLPHDP : :::: .:::. : ::::..:.:.: :.. .:.::: :: :.: ::.::..: ::: CCDS66 PPGQFVPFQTQQSRSPLQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDP 240 250 260 270 280 290 260 270 280 290 300 310 pF1KSD LHQELSFGVPYSHMMPRRLSTQ-RYRLQQPLPPPPPPPPPPPYYPSFLPYFLSMLPMSPT ::::.:::::: .:::::. . ::: :::.:: :::.::.::: :::::. : CCDS66 LHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPP-------PPYHPSLLPYVLSMLPV-PP 300 310 320 330 340 350 320 330 340 350 360 370 pF1KSD AMGPTISLDLDVDDVEMENYEALLNLAERLGDAKPRGLTKADIEQLPSYRFNPDSHQSEQ :.:::.:..:::.: :.::::::::::::::.:::::::::::::::::::::..::::: CCDS66 AVGPTFSFELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQ 360 370 380 390 400 410 380 390 400 410 420 430 pF1KSD TLCVVCFSDFEARQLLRVLPCNHEFHTKCVDKWLKANRTCPICRADASEVPREAE ::::::. :::.::::::::::::::.::::::::::::::::::::::: :..: CCDS66 TLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRDSE 420 430 440 450 460 >>CCDS6603.1 RNF38 gene_id:152006|Hs108|chr9 (515 aa) initn: 1381 init1: 730 opt: 1836 Z-score: 960.1 bits: 187.0 E(32554): 3.7e-47 Smith-Waterman score: 1836; 60.9% identity (79.8% similar) in 445 aa overlap (1-432:84-515) 10 20 30 pF1KSD MRPWALAVTRWPPSAPVGQRRFSAGPGSTP :::: .. .: :::. .:..::. .:: CCDS66 QSEDSPSPKRQRLSHSVFDYTSASPAPSPPMRPWEMTSNRQPPSVRPSQHHFSGERCNTP 60 70 80 90 100 110 40 50 60 70 80 pF1KSD GQLWGSPGLEGPLASPPARDERLPSQQPPSRPP---HLP------VEERRASAPAGGSPR .. :: :. .: .:: .. :. ::: .:: :: : . ::: CCDS66 ARNRRSP----PVRRQRGRRDRLSRHNSISQDENYHHLPYAQQQAIEEPRAFHPPNVSPR 120 130 140 150 160 90 100 110 120 130 pF1KSD MLHPAT---QQSPFMVDLHEQVHQGPVPLSYTVTTVTTQGFPLPTGQHIPGCSAQQLPAC .::::. ::. :::.:.:.::: ::.:::::::. .:.:: ::::::.::.::.:.: CCDS66 LLHPAAHPPQQNAVMVDIHDQLHQGTVPVSYTVTTVAPHGIPLCTGQHIPACSTQQVPGC 170 180 190 200 210 220 140 150 160 170 180 190 pF1KSD SVMFSGQHYPLCCLPPPLIQACTMQQLPVPYQAYPHLISSDHYILHPPPPAPPPQPTHMA ::.::::: :.: .:::..:::..:.::::: :.: ::::: ...::: .: .: :. CCDS66 SVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLIHPPHLSPH-HPPHLP 230 240 250 260 270 280 200 210 220 230 240 250 pF1KSD PLGQFVSLQTQHPRMPLQRLDNDVDLRGDQPSLGSFTYSTSAPGPALSPSVPLHYLPHDP : :::: .:::. : ::::..:.:.: :.. .:.::: :: :.: ::.::..: ::: CCDS66 PPGQFVPFQTQQSRSPLQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDP 290 300 310 320 330 340 260 270 280 290 300 310 pF1KSD LHQELSFGVPYSHMMPRRLSTQ-RYRLQQPLPPPPPPPPPPPYYPSFLPYFLSMLPMSPT ::::.:::::: .:::::. . ::: :::.:: :::.::.::: :::::. : CCDS66 LHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPP-------PPYHPSLLPYVLSMLPV-PP 350 360 370 380 390 400 320 330 340 350 360 370 pF1KSD AMGPTISLDLDVDDVEMENYEALLNLAERLGDAKPRGLTKADIEQLPSYRFNPDSHQSEQ :.:::.:..:::.: :.::::::::::::::.:::::::::::::::::::::..::::: CCDS66 AVGPTFSFELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQ 410 420 430 440 450 460 380 390 400 410 420 430 pF1KSD TLCVVCFSDFEARQLLRVLPCNHEFHTKCVDKWLKANRTCPICRADASEVPREAE ::::::. :::.::::::::::::::.::::::::::::::::::::::: :..: CCDS66 TLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRDSE 470 480 490 500 510 432 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 19:01:53 2016 done: Thu Nov 3 19:01:54 2016 Total Scan time: 3.850 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]