Result of FASTA (omim) for pF1KSDA1074

KOP
KOP Flexi HaloTag ORF List search
Result of FASTA (omim) for pF1KSDA1074
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KSDA1074, 1709 aa
  1>>>pF1KSDA1074 1709 - 1709 aa - 1709 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 19.9109+/-0.000772; mu= -49.4546+/- 0.047
 mean_var=894.3906+/-190.108, 0's: 0 Z-trim(115.7): 429  B-trim: 474 in 1/55
 Lambda= 0.042886
 statistics sampled from 25963 (26366) to 25963 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.309), width:  16
 Scan time: 20.820

The best scores are:                                      opt bits E(85289)
NP_001242982 (OMIM: 188000,610855) ankyrin repeat  (1709) 10901 692.3 9.5e-198
NP_055730 (OMIM: 188000,610855) ankyrin repeat dom (1710) 10889 691.6 1.6e-197
XP_006717486 (OMIM: 188000,610855) PREDICTED: anky (2072) 7321 470.9 5.3e-131
XP_016871418 (OMIM: 188000,610855) PREDICTED: anky (2108) 7048 454.0 6.6e-126
XP_016871417 (OMIM: 188000,610855) PREDICTED: anky (2112) 7048 454.0 6.6e-126
XP_006717488 (OMIM: 188000,610855) PREDICTED: anky (2031) 7047 453.9 6.7e-126
XP_016871421 (OMIM: 188000,610855) PREDICTED: anky (2031) 7047 453.9 6.7e-126
XP_016871419 (OMIM: 188000,610855) PREDICTED: anky (2062) 7047 453.9 6.8e-126
XP_011517718 (OMIM: 188000,610855) PREDICTED: anky (2062) 7047 453.9 6.8e-126
XP_016871420 (OMIM: 188000,610855) PREDICTED: anky (2062) 7047 453.9 6.8e-126
XP_016871422 (OMIM: 188000,610855) PREDICTED: anky (1656) 4569 300.6   8e-80
XP_016871423 (OMIM: 188000,610855) PREDICTED: anky (1037) 3578 239.2 1.5e-61
NP_001002920 (OMIM: 608915) POTE ankyrin domain fa ( 452)  887 72.5 9.9e-12
NP_001138501 (OMIM: 616565) ankyrin repeat domain- (1392)  824 68.8 3.9e-10
XP_011542818 (OMIM: 608915) PREDICTED: POTE ankyri ( 310)  788 66.3   5e-10
NP_001005365 (OMIM: 608915) POTE ankyrin domain fa ( 498)  788 66.4 7.5e-10
XP_016877347 (OMIM: 608912) PREDICTED: POTE ankyri ( 339)  743 63.5 3.7e-09
XP_011542096 (OMIM: 608912) PREDICTED: POTE ankyri ( 339)  743 63.5 3.7e-09
XP_006720418 (OMIM: 608912) PREDICTED: POTE ankyri ( 347)  743 63.5 3.8e-09
NP_001129685 (OMIM: 608913) POTE ankyrin domain fa ( 545)  746 63.8 4.9e-09
NP_001005356 (OMIM: 608916) POTE ankyrin domain fa ( 508)  744 63.7   5e-09
XP_011527852 (OMIM: 607549) PREDICTED: POTE ankyri ( 376)  737 63.2 5.3e-09
XP_006724060 (OMIM: 607549) PREDICTED: POTE ankyri ( 384)  737 63.2 5.4e-09
NP_001264233 (OMIM: 608912) POTE ankyrin domain fa ( 544)  743 63.6 5.6e-09
XP_011509518 (OMIM: 608914) PREDICTED: POTE ankyri ( 957)  750 64.2 6.7e-09
XP_016859650 (OMIM: 608914) PREDICTED: POTE ankyri (1075)  750 64.2 7.4e-09
NP_001077007 (OMIM: 608914) POTE ankyrin domain fa (1075)  750 64.2 7.4e-09
NP_778146 (OMIM: 607549) POTE ankyrin domain famil ( 584)  737 63.3 7.7e-09
XP_011523964 (OMIM: 616565) PREDICTED: ankyrin rep (1525)  754 64.5 8.4e-09
XP_006722388 (OMIM: 616565) PREDICTED: ankyrin rep (1511)  752 64.4 9.1e-09
XP_016855045 (OMIM: 608912) PREDICTED: LOW QUALITY ( 546)  725 62.5 1.2e-08
XP_011518059 (OMIM: 610856) PREDICTED: ankyrin rep (1585)  735 63.4   2e-08
XP_011523966 (OMIM: 616565) PREDICTED: ankyrin rep (1149)  667 59.1 2.8e-07
XP_011523968 (OMIM: 616565) PREDICTED: ankyrin rep ( 850)  660 58.6 2.9e-07
NP_062618 (OMIM: 610731) ankyrin repeat domain-con ( 254)  634 56.7 3.1e-07
XP_016872372 (OMIM: 610856) PREDICTED: ankyrin rep ( 825)  657 58.4 3.2e-07
XP_011523967 (OMIM: 616565) PREDICTED: ankyrin rep (1076)  660 58.6 3.5e-07
XP_011518060 (OMIM: 610856) PREDICTED: ankyrin rep (1192)  641 57.5 8.7e-07
NP_443723 (OMIM: 610856) ankyrin repeat domain-con (1341)  576 53.5 1.6e-05
XP_016861677 (OMIM: 602509) PREDICTED: golgin subf (2195)  535 51.0 0.00014
XP_005265132 (OMIM: 602509) PREDICTED: golgin subf (2214)  535 51.0 0.00014
NP_002069 (OMIM: 602509) golgin subfamily A member (2230)  535 51.1 0.00014
XP_016861676 (OMIM: 602509) PREDICTED: golgin subf (2236)  535 51.1 0.00014
NP_001166184 (OMIM: 602509) golgin subfamily A mem (2243)  535 51.1 0.00014
XP_005265131 (OMIM: 602509) PREDICTED: golgin subf (2245)  535 51.1 0.00014
XP_006713173 (OMIM: 602509) PREDICTED: golgin subf (2250)  535 51.1 0.00014
XP_016861674 (OMIM: 602509) PREDICTED: golgin subf (2251)  535 51.1 0.00014
XP_016861675 (OMIM: 602509) PREDICTED: golgin subf (2251)  535 51.1 0.00014
XP_005265130 (OMIM: 602509) PREDICTED: golgin subf (2252)  535 51.1 0.00014
XP_005265129 (OMIM: 602509) PREDICTED: golgin subf (2269)  535 51.1 0.00014


>>NP_001242982 (OMIM: 188000,610855) ankyrin repeat doma  (1709 aa)
 initn: 10901 init1: 10901 opt: 10901  Z-score: 3671.2  bits: 692.3 E(85289): 9.5e-198
Smith-Waterman score: 10901; 99.9% identity (100.0% similar) in 1709 aa overlap (1-1709:1-1709)

               10        20        30        40        50        60
pF1KSD MKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
NP_001 MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD NNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKEN
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KSD KEYASGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEYASGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDEG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KSD RPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKD
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KSD SVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KSD VEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLE
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KSD MELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KSD HSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIK
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KSD QNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRD
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KSD QSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFH
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KSD HTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQS
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KSD ENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECN
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KSD HLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKK
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KSD KLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLN
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KSD ANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGE
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KSD FSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQ
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KSD KKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFL
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KSD QAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLYLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLYLE
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KSD ELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSLDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSLDL
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KSD NRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASPLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASPLG
             1630      1640      1650      1660      1670      1680

             1690      1700         
pF1KSD STDESNLNQDLVWKASREYVQVLKKNYMI
       :::::::::::::::::::::::::::::
NP_001 STDESNLNQDLVWKASREYVQVLKKNYMI
             1690      1700         

>>NP_055730 (OMIM: 188000,610855) ankyrin repeat domain-  (1710 aa)
 initn: 6985 init1: 6985 opt: 10889  Z-score: 3667.2  bits: 691.6 E(85289): 1.6e-197
Smith-Waterman score: 10889; 99.9% identity (99.9% similar) in 1710 aa overlap (1-1709:1-1710)

               10        20        30        40        50        60
pF1KSD MKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
NP_055 MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KSD DSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNV
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KSD GMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSE
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KSD NNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKEN
              550       560       570       580       590       600

               610       620       630       640       650         
pF1KSD KEYAS-GPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDE
       ::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDE
              610       620       630       640       650       660

     660       670       680       690       700       710         
pF1KSD GRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECK
              670       680       690       700       710       720

     720       730       740       750       760       770         
pF1KSD DSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQ
              730       740       750       760       770       780

     780       790       800       810       820       830         
pF1KSD KVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTL
              790       800       810       820       830       840

     840       850       860       870       880       890         
pF1KSD EMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSEN
              850       860       870       880       890       900

     900       910       920       930       940       950         
pF1KSD SHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTI
              910       920       930       940       950       960

     960       970       980       990      1000      1010         
pF1KSD KQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDR
              970       980       990      1000      1010      1020

    1020      1030      1040      1050      1060      1070         
pF1KSD DQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEF
             1030      1040      1050      1060      1070      1080

    1080      1090      1100      1110      1120      1130         
pF1KSD HHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQ
             1090      1100      1110      1120      1130      1140

    1140      1150      1160      1170      1180      1190         
pF1KSD SENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISEC
             1150      1160      1170      1180      1190      1200

    1200      1210      1220      1230      1240      1250         
pF1KSD NHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLK
             1210      1220      1230      1240      1250      1260

    1260      1270      1280      1290      1300      1310         
pF1KSD KKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLL
             1270      1280      1290      1300      1310      1320

    1320      1330      1340      1350      1360      1370         
pF1KSD NANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENG
             1330      1340      1350      1360      1370      1380

    1380      1390      1400      1410      1420      1430         
pF1KSD EFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTV
             1390      1400      1410      1420      1430      1440

    1440      1450      1460      1470      1480      1490         
pF1KSD QKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLF
             1450      1460      1470      1480      1490      1500

    1500      1510      1520      1530      1540      1550         
pF1KSD LQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLYL
             1510      1520      1530      1540      1550      1560

    1560      1570      1580      1590      1600      1610         
pF1KSD EELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSLD
             1570      1580      1590      1600      1610      1620

    1620      1630      1640      1650      1660      1670         
pF1KSD LNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASPL
             1630      1640      1650      1660      1670      1680

    1680      1690      1700         
pF1KSD GSTDESNLNQDLVWKASREYVQVLKKNYMI
       ::::::::::::::::::::::::::::::
NP_055 GSTDESNLNQDLVWKASREYVQVLKKNYMI
             1690      1700      1710

>>XP_006717486 (OMIM: 188000,610855) PREDICTED: ankyrin   (2072 aa)
 initn: 10530 init1: 6966 opt: 7321  Z-score: 2472.8  bits: 470.9 E(85289): 5.3e-131
Smith-Waterman score: 8015; 79.1% identity (79.1% similar) in 1741 aa overlap (332-1709:332-2072)

             310       320       330       340       350       360 
pF1KSD GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
                                     ::::::::::::::::::::::::::::::
XP_006 GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
             310       320       330       340       350       360 

             370       380       390       400       410       420 
pF1KSD PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
             370       380       390       400       410       420 

             430       440       450       460       470       480 
pF1KSD SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
             430       440       450       460       470       480 

             490       500       510       520       530       540 
pF1KSD MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
             490       500       510       520       530       540 

                                                                   
pF1KSD NQPQ--------------------------------------------------------
       ::::                                                        
XP_006 NQPQDKVILKTCTLTEKTSEKQNKQINRPLSCLQKMSQEPELNKECDREDVSVYSGLPCV
             550       560       570       580       590       600 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 QNDEEMWTKQGKLEWKNNLKLITNELKQSCGETCEKYKITASPGEESLHDNSKGGTNLKE
             610       620       630       640       650       660 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 IPSSLTNNILDCDEKDSPVSVLFQALPEQKVLSLENGFSFPSYSGSPEYACQSSSKPYLN
             670       680       690       700       710       720 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 ENKLGHENVNKPDTEHVFNTDENFYNDTENKKVRNPEVVTGVMKEEFDKTKNMNRNTTNW
             730       740       750       760       770       780 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 KLDIRRVPQYSDPKRPFDLICSKEMNHMFHIKRHSISAGTDAYKKTKPIQNLFQKPLYDH
             790       800       810       820       830       840 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 CSANNYKSMEPELENVRSSPPRGDRTSKVSLKEELQQDMQRFKNEIGMLKVEFQALEKEK
             850       860       870       880       890       900 

               550       560       570       580       590         
pF1KSD ------VEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQLQKEVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             910       920       930       940       950       960 

     600        610       620       630       640       650        
pF1KSD NKEYAS-GPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
             970       980       990      1000      1010      1020 

      660       670       680       690       700       710        
pF1KSD EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
            1030      1040      1050      1060      1070      1080 

      720       730       740       750       760       770        
pF1KSD KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
            1090      1100      1110      1120      1130      1140 

      780       790       800       810       820       830        
pF1KSD QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
            1150      1160      1170      1180      1190      1200 

      840       850       860       870       880       890        
pF1KSD LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
            1210      1220      1230      1240      1250      1260 

      900       910       920       930       940       950        
pF1KSD NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
            1270      1280      1290      1300      1310      1320 

      960       970       980       990      1000      1010        
pF1KSD IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
            1330      1340      1350      1360      1370      1380 

     1020      1030      1040      1050      1060      1070        
pF1KSD RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
            1390      1400      1410      1420      1430      1440 

     1080      1090      1100      1110      1120      1130        
pF1KSD FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
            1450      1460      1470      1480      1490      1500 

     1140      1150      1160      1170      1180      1190        
pF1KSD QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
            1510      1520      1530      1540      1550      1560 

     1200      1210      1220      1230      1240      1250        
pF1KSD CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
            1570      1580      1590      1600      1610      1620 

     1260      1270      1280      1290      1300      1310        
pF1KSD KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
            1630      1640      1650      1660      1670      1680 

     1320      1330      1340      1350      1360      1370        
pF1KSD LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
            1690      1700      1710      1720      1730      1740 

     1380      1390      1400      1410      1420      1430        
pF1KSD GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
            1750      1760      1770      1780      1790      1800 

     1440      1450      1460      1470      1480      1490        
pF1KSD VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
            1810      1820      1830      1840      1850      1860 

     1500      1510      1520      1530      1540      1550        
pF1KSD FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
            1870      1880      1890      1900      1910      1920 

     1560      1570      1580      1590      1600      1610        
pF1KSD LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
            1930      1940      1950      1960      1970      1980 

     1620      1630      1640      1650      1660      1670        
pF1KSD DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASP
            1990      2000      2010      2020      2030      2040 

     1680      1690      1700         
pF1KSD LGSTDESNLNQDLVWKASREYVQVLKKNYMI
       :::::::::::::::::::::::::::::::
XP_006 LGSTDESNLNQDLVWKASREYVQVLKKNYMI
            2050      2060      2070  

>--
 initn: 2140 init1: 2140 opt: 2140  Z-score: 740.4  bits: 150.3 E(85289): 1.7e-34
Smith-Waterman score: 2140; 99.7% identity (100.0% similar) in 331 aa overlap (1-331:1-331)

               10        20        30        40        50        60
pF1KSD MKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_006 MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
       :::::::::::::::::::::::::::::::                             
XP_006 TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
                                                                   
XP_006 EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
              370       380       390       400       410       420

>>XP_016871418 (OMIM: 188000,610855) PREDICTED: ankyrin   (2108 aa)
 initn: 10254 init1: 6686 opt: 7048  Z-score: 2381.4  bits: 454.0 E(85289): 6.6e-126
Smith-Waterman score: 7703; 78.2% identity (78.4% similar) in 1704 aa overlap (328-1668:328-2027)

       300       310       320       330       340       350       
pF1KSD TVRTGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGL
                                     ::::::::::::::::::::::::::::::
XP_016 TVRTGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGL
       300       310       320       330       340       350       

       360       370       380       390       400       410       
pF1KSD MKEEPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKEEPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIE
       360       370       380       390       400       410       

       420       430       440       450       460       470       
pF1KSD SPWDSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPWDSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDT
       420       430       440       450       460       470       

       480       490       500       510       520       530       
pF1KSD RNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQERE
       ::     ::.::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RN----HAHIESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQERE
           480       490       500       510       520       530   

       540                                                         
pF1KSD GSENNQPQ----------------------------------------------------
       ::::::::                                                    
XP_016 GSENNQPQDKVILKTCTLTEKTSEKQNKQINRPLSCLQKMSQEPELNKECDREDVSVYSG
           540       550       560       570       580       590   

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 LPCVQNDEEMWTKQGKLEWKNNLKLITNELKQSCGETCEKYKITASPGEESLHDNSKGGT
           600       610       620       630       640       650   

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 NLKEIPSSLTNNILDCDEKDSPVSVLFQALPEQKVLSLENGFSFPSYSGSPEYACQSSSK
           660       670       680       690       700       710   

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 PYLNENKLGHENVNKPDTEHVFNTDENFYNDTENKKVRNPEVVTGVMKEEFDKTKNMNRN
           720       730       740       750       760       770   

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 TTNWKLDIRRVPQYSDPKRPFDLICSKEMNHMFHIKRHSISAGTDAYKKTKPIQNLFQKP
           780       790       800       810       820       830   

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 LYDHCSANNYKSMEPELENVRSSPPRGDRTSKVSLKEELQQDMQRFKNEIGMLKVEFQAL
           840       850       860       870       880       890   

                   550       560       570       580       590     
pF1KSD ----------VEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQF
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEKVQLQKEVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQF
           900       910       920       930       940       950   

         600        610       620       630       640       650    
pF1KSD PRKENKEYAS-GPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSE
       :::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRKENKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSE
           960       970       980       990      1000      1010   

          660       670       680       690       700       710    
pF1KSD IDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQL
          1020      1030      1040      1050      1060      1070   

          720       730       740       750       760       770    
pF1KSD GMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKS
          1080      1090      1100      1110      1120      1130   

          780       790       800       810       820       830    
pF1KSD QLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLEL
          1140      1150      1160      1170      1180      1190   

          840       850       860       870       880       890    
pF1KSD SLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKK
          1200      1210      1220      1230      1240      1250   

          900       910       920       930       940       950    
pF1KSD MNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNED
          1260      1270      1280      1290      1300      1310   

          960       970       980       990      1000      1010    
pF1KSD LQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAA
          1320      1330      1340      1350      1360      1370   

         1020      1030      1040      1050      1060      1070    
pF1KSD AIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNS
          1380      1390      1400      1410      1420      1430   

         1080      1090      1100      1110      1120      1130    
pF1KSD LEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEER
          1440      1450      1460      1470      1480      1490   

         1140      1150      1160      1170      1180      1190    
pF1KSD LSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKE
          1500      1510      1520      1530      1540      1550   

         1200      1210      1220      1230      1240      1250    
pF1KSD LISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDE
          1560      1570      1580      1590      1600      1610   

         1260      1270      1280      1290      1300      1310    
pF1KSD TQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEEL
          1620      1630      1640      1650      1660      1670   

         1320      1330      1340      1350      1360      1370    
pF1KSD QKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLN
          1680      1690      1700      1710      1720      1730   

         1380      1390      1400      1410      1420      1430    
pF1KSD EYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELL
          1740      1750      1760      1770      1780      1790   

         1440      1450      1460      1470      1480      1490    
pF1KSD SMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLK
          1800      1810      1820      1830      1840      1850   

         1500      1510      1520      1530      1540      1550    
pF1KSD EVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKY
          1860      1870      1880      1890      1900      1910   

         1560      1570      1580      1590      1600      1610    
pF1KSD KQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNL
          1920      1930      1940      1950      1960      1970   

         1620      1630      1640      1650      1660      1670    
pF1KSD NNSLDLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGS
       :::::::::::::::::::::::::::::::::::::::::::::::::::...      
XP_016 NNSLDLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEGTSPAYSDL
          1980      1990      2000      2010      2020      2030   

         1680      1690      1700                                  
pF1KSD IASPLGSTDESNLNQDLVWKASREYVQVLKKNYMI                         
                                                                   
XP_016 SELPGPDLFPLPACSSLPSSSPCLLLTQQKATGWSTSTTPSPDDFTTVSLAAFHLEEVEK
          2040      2050      2060      2070      2080      2090   

>--
 initn: 2117 init1: 2117 opt: 2117  Z-score: 732.6  bits: 148.9 E(85289): 4.6e-34
Smith-Waterman score: 2117; 99.7% identity (100.0% similar) in 327 aa overlap (1-327:1-327)

               10        20        30        40        50        60
pF1KSD MKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
       :::::::::::::::::::::::::::                                 
XP_016 TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
              310       320       330       340       350       360

>>XP_016871417 (OMIM: 188000,610855) PREDICTED: ankyrin   (2112 aa)
 initn: 10292 init1: 6686 opt: 7048  Z-score: 2381.4  bits: 454.0 E(85289): 6.6e-126
Smith-Waterman score: 7742; 78.5% identity (78.6% similar) in 1700 aa overlap (332-1668:332-2031)

             310       320       330       340       350       360 
pF1KSD GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
                                     ::::::::::::::::::::::::::::::
XP_016 GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
             310       320       330       340       350       360 

             370       380       390       400       410       420 
pF1KSD PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
             370       380       390       400       410       420 

             430       440       450       460       470       480 
pF1KSD SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
             430       440       450       460       470       480 

             490       500       510       520       530       540 
pF1KSD MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
             490       500       510       520       530       540 

                                                                   
pF1KSD NQPQ--------------------------------------------------------
       ::::                                                        
XP_016 NQPQDKVILKTCTLTEKTSEKQNKQINRPLSCLQKMSQEPELNKECDREDVSVYSGLPCV
             550       560       570       580       590       600 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 QNDEEMWTKQGKLEWKNNLKLITNELKQSCGETCEKYKITASPGEESLHDNSKGGTNLKE
             610       620       630       640       650       660 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 IPSSLTNNILDCDEKDSPVSVLFQALPEQKVLSLENGFSFPSYSGSPEYACQSSSKPYLN
             670       680       690       700       710       720 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 ENKLGHENVNKPDTEHVFNTDENFYNDTENKKVRNPEVVTGVMKEEFDKTKNMNRNTTNW
             730       740       750       760       770       780 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 KLDIRRVPQYSDPKRPFDLICSKEMNHMFHIKRHSISAGTDAYKKTKPIQNLFQKPLYDH
             790       800       810       820       830       840 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 CSANNYKSMEPELENVRSSPPRGDRTSKVSLKEELQQDMQRFKNEIGMLKVEFQALEKEK
             850       860       870       880       890       900 

               550       560       570       580       590         
pF1KSD ------VEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLQKEVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             910       920       930       940       950       960 

     600        610       620       630       640       650        
pF1KSD NKEYAS-GPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
             970       980       990      1000      1010      1020 

      660       670       680       690       700       710        
pF1KSD EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
            1030      1040      1050      1060      1070      1080 

      720       730       740       750       760       770        
pF1KSD KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
            1090      1100      1110      1120      1130      1140 

      780       790       800       810       820       830        
pF1KSD QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
            1150      1160      1170      1180      1190      1200 

      840       850       860       870       880       890        
pF1KSD LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
            1210      1220      1230      1240      1250      1260 

      900       910       920       930       940       950        
pF1KSD NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
            1270      1280      1290      1300      1310      1320 

      960       970       980       990      1000      1010        
pF1KSD IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
            1330      1340      1350      1360      1370      1380 

     1020      1030      1040      1050      1060      1070        
pF1KSD RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
            1390      1400      1410      1420      1430      1440 

     1080      1090      1100      1110      1120      1130        
pF1KSD FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
            1450      1460      1470      1480      1490      1500 

     1140      1150      1160      1170      1180      1190        
pF1KSD QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
            1510      1520      1530      1540      1550      1560 

     1200      1210      1220      1230      1240      1250        
pF1KSD CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
            1570      1580      1590      1600      1610      1620 

     1260      1270      1280      1290      1300      1310        
pF1KSD KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
            1630      1640      1650      1660      1670      1680 

     1320      1330      1340      1350      1360      1370        
pF1KSD LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
            1690      1700      1710      1720      1730      1740 

     1380      1390      1400      1410      1420      1430        
pF1KSD GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
            1750      1760      1770      1780      1790      1800 

     1440      1450      1460      1470      1480      1490        
pF1KSD VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
            1810      1820      1830      1840      1850      1860 

     1500      1510      1520      1530      1540      1550        
pF1KSD FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
            1870      1880      1890      1900      1910      1920 

     1560      1570      1580      1590      1600      1610        
pF1KSD LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
            1930      1940      1950      1960      1970      1980 

     1620      1630      1640      1650      1660      1670        
pF1KSD DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASP
       :::::::::::::::::::::::::::::::::::::::::::::::...          
XP_016 DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEGTSPAYSDLSELP
            1990      2000      2010      2020      2030      2040 

     1680      1690      1700                                      
pF1KSD LGSTDESNLNQDLVWKASREYVQVLKKNYMI                             
                                                                   
XP_016 GPDLFPLPACSSLPSSSPCLLLTQQKATGWSTSTTPSPDDFTTVSLAAFHLEEVEKGEPV
            2050      2060      2070      2080      2090      2100 

>--
 initn: 2140 init1: 2140 opt: 2140  Z-score: 740.3  bits: 150.3 E(85289): 1.7e-34
Smith-Waterman score: 2140; 99.7% identity (100.0% similar) in 331 aa overlap (1-331:1-331)

               10        20        30        40        50        60
pF1KSD MKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
       :::::::::::::::::::::::::::::::                             
XP_016 TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
                                                                   
XP_016 EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
              370       380       390       400       410       420

>>XP_006717488 (OMIM: 188000,610855) PREDICTED: ankyrin   (2031 aa)
 initn: 10256 init1: 6692 opt: 7047  Z-score: 2381.3  bits: 453.9 E(85289): 6.7e-126
Smith-Waterman score: 7741; 78.6% identity (78.6% similar) in 1697 aa overlap (332-1665:332-2028)

             310       320       330       340       350       360 
pF1KSD GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
                                     ::::::::::::::::::::::::::::::
XP_006 GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
             310       320       330       340       350       360 

             370       380       390       400       410       420 
pF1KSD PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
             370       380       390       400       410       420 

             430       440       450       460       470       480 
pF1KSD SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
             430       440       450       460       470       480 

             490       500       510       520       530       540 
pF1KSD MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
             490       500       510       520       530       540 

                                                                   
pF1KSD NQPQ--------------------------------------------------------
       ::::                                                        
XP_006 NQPQDKVILKTCTLTEKTSEKQNKQINRPLSCLQKMSQEPELNKECDREDVSVYSGLPCV
             550       560       570       580       590       600 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 QNDEEMWTKQGKLEWKNNLKLITNELKQSCGETCEKYKITASPGEESLHDNSKGGTNLKE
             610       620       630       640       650       660 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 IPSSLTNNILDCDEKDSPVSVLFQALPEQKVLSLENGFSFPSYSGSPEYACQSSSKPYLN
             670       680       690       700       710       720 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 ENKLGHENVNKPDTEHVFNTDENFYNDTENKKVRNPEVVTGVMKEEFDKTKNMNRNTTNW
             730       740       750       760       770       780 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 KLDIRRVPQYSDPKRPFDLICSKEMNHMFHIKRHSISAGTDAYKKTKPIQNLFQKPLYDH
             790       800       810       820       830       840 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_006 CSANNYKSMEPELENVRSSPPRGDRTSKVSLKEELQQDMQRFKNEIGMLKVEFQALEKEK
             850       860       870       880       890       900 

               550       560       570       580       590         
pF1KSD ------VEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQLQKEVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             910       920       930       940       950       960 

     600        610       620       630       640       650        
pF1KSD NKEYAS-GPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
             970       980       990      1000      1010      1020 

      660       670       680       690       700       710        
pF1KSD EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
            1030      1040      1050      1060      1070      1080 

      720       730       740       750       760       770        
pF1KSD KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
            1090      1100      1110      1120      1130      1140 

      780       790       800       810       820       830        
pF1KSD QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
            1150      1160      1170      1180      1190      1200 

      840       850       860       870       880       890        
pF1KSD LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
            1210      1220      1230      1240      1250      1260 

      900       910       920       930       940       950        
pF1KSD NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
            1270      1280      1290      1300      1310      1320 

      960       970       980       990      1000      1010        
pF1KSD IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
            1330      1340      1350      1360      1370      1380 

     1020      1030      1040      1050      1060      1070        
pF1KSD RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
            1390      1400      1410      1420      1430      1440 

     1080      1090      1100      1110      1120      1130        
pF1KSD FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
            1450      1460      1470      1480      1490      1500 

     1140      1150      1160      1170      1180      1190        
pF1KSD QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
            1510      1520      1530      1540      1550      1560 

     1200      1210      1220      1230      1240      1250        
pF1KSD CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
            1570      1580      1590      1600      1610      1620 

     1260      1270      1280      1290      1300      1310        
pF1KSD KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
            1630      1640      1650      1660      1670      1680 

     1320      1330      1340      1350      1360      1370        
pF1KSD LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
            1690      1700      1710      1720      1730      1740 

     1380      1390      1400      1410      1420      1430        
pF1KSD GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
            1750      1760      1770      1780      1790      1800 

     1440      1450      1460      1470      1480      1490        
pF1KSD VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
            1810      1820      1830      1840      1850      1860 

     1500      1510      1520      1530      1540      1550        
pF1KSD FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
            1870      1880      1890      1900      1910      1920 

     1560      1570      1580      1590      1600      1610        
pF1KSD LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
            1930      1940      1950      1960      1970      1980 

     1620      1630      1640      1650      1660      1670        
pF1KSD DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASP
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_006 DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEGTF          
            1990      2000      2010      2020      2030           

     1680      1690      1700         
pF1KSD LGSTDESNLNQDLVWKASREYVQVLKKNYMI

>--
 initn: 2140 init1: 2140 opt: 2140  Z-score: 740.5  bits: 150.3 E(85289): 1.6e-34
Smith-Waterman score: 2140; 99.7% identity (100.0% similar) in 331 aa overlap (1-331:1-331)

               10        20        30        40        50        60
pF1KSD MKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_006 MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
       :::::::::::::::::::::::::::::::                             
XP_006 TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
                                                                   
XP_006 EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
              370       380       390       400       410       420

>>XP_016871421 (OMIM: 188000,610855) PREDICTED: ankyrin   (2031 aa)
 initn: 10256 init1: 6692 opt: 7047  Z-score: 2381.3  bits: 453.9 E(85289): 6.7e-126
Smith-Waterman score: 7741; 78.6% identity (78.6% similar) in 1697 aa overlap (332-1665:332-2028)

             310       320       330       340       350       360 
pF1KSD GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
                                     ::::::::::::::::::::::::::::::
XP_016 GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
             310       320       330       340       350       360 

             370       380       390       400       410       420 
pF1KSD PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
             370       380       390       400       410       420 

             430       440       450       460       470       480 
pF1KSD SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
             430       440       450       460       470       480 

             490       500       510       520       530       540 
pF1KSD MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
             490       500       510       520       530       540 

                                                                   
pF1KSD NQPQ--------------------------------------------------------
       ::::                                                        
XP_016 NQPQDKVILKTCTLTEKTSEKQNKQINRPLSCLQKMSQEPELNKECDREDVSVYSGLPCV
             550       560       570       580       590       600 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 QNDEEMWTKQGKLEWKNNLKLITNELKQSCGETCEKYKITASPGEESLHDNSKGGTNLKE
             610       620       630       640       650       660 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 IPSSLTNNILDCDEKDSPVSVLFQALPEQKVLSLENGFSFPSYSGSPEYACQSSSKPYLN
             670       680       690       700       710       720 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 ENKLGHENVNKPDTEHVFNTDENFYNDTENKKVRNPEVVTGVMKEEFDKTKNMNRNTTNW
             730       740       750       760       770       780 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 KLDIRRVPQYSDPKRPFDLICSKEMNHMFHIKRHSISAGTDAYKKTKPIQNLFQKPLYDH
             790       800       810       820       830       840 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 CSANNYKSMEPELENVRSSPPRGDRTSKVSLKEELQQDMQRFKNEIGMLKVEFQALEKEK
             850       860       870       880       890       900 

               550       560       570       580       590         
pF1KSD ------VEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLQKEVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             910       920       930       940       950       960 

     600        610       620       630       640       650        
pF1KSD NKEYAS-GPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
             970       980       990      1000      1010      1020 

      660       670       680       690       700       710        
pF1KSD EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
            1030      1040      1050      1060      1070      1080 

      720       730       740       750       760       770        
pF1KSD KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
            1090      1100      1110      1120      1130      1140 

      780       790       800       810       820       830        
pF1KSD QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
            1150      1160      1170      1180      1190      1200 

      840       850       860       870       880       890        
pF1KSD LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
            1210      1220      1230      1240      1250      1260 

      900       910       920       930       940       950        
pF1KSD NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
            1270      1280      1290      1300      1310      1320 

      960       970       980       990      1000      1010        
pF1KSD IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
            1330      1340      1350      1360      1370      1380 

     1020      1030      1040      1050      1060      1070        
pF1KSD RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
            1390      1400      1410      1420      1430      1440 

     1080      1090      1100      1110      1120      1130        
pF1KSD FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
            1450      1460      1470      1480      1490      1500 

     1140      1150      1160      1170      1180      1190        
pF1KSD QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
            1510      1520      1530      1540      1550      1560 

     1200      1210      1220      1230      1240      1250        
pF1KSD CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
            1570      1580      1590      1600      1610      1620 

     1260      1270      1280      1290      1300      1310        
pF1KSD KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
            1630      1640      1650      1660      1670      1680 

     1320      1330      1340      1350      1360      1370        
pF1KSD LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
            1690      1700      1710      1720      1730      1740 

     1380      1390      1400      1410      1420      1430        
pF1KSD GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
            1750      1760      1770      1780      1790      1800 

     1440      1450      1460      1470      1480      1490        
pF1KSD VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
            1810      1820      1830      1840      1850      1860 

     1500      1510      1520      1530      1540      1550        
pF1KSD FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
            1870      1880      1890      1900      1910      1920 

     1560      1570      1580      1590      1600      1610        
pF1KSD LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
            1930      1940      1950      1960      1970      1980 

     1620      1630      1640      1650      1660      1670        
pF1KSD DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASP
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_016 DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEGTF          
            1990      2000      2010      2020      2030           

     1680      1690      1700         
pF1KSD LGSTDESNLNQDLVWKASREYVQVLKKNYMI

>--
 initn: 2140 init1: 2140 opt: 2140  Z-score: 740.5  bits: 150.3 E(85289): 1.6e-34
Smith-Waterman score: 2140; 99.7% identity (100.0% similar) in 331 aa overlap (1-331:1-331)

               10        20        30        40        50        60
pF1KSD MKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
       :::::::::::::::::::::::::::::::                             
XP_016 TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
                                                                   
XP_016 EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
              370       380       390       400       410       420

>>XP_016871419 (OMIM: 188000,610855) PREDICTED: ankyrin   (2062 aa)
 initn: 10256 init1: 6692 opt: 7047  Z-score: 2381.2  bits: 453.9 E(85289): 6.8e-126
Smith-Waterman score: 7741; 78.6% identity (78.6% similar) in 1697 aa overlap (332-1665:332-2028)

             310       320       330       340       350       360 
pF1KSD GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
                                     ::::::::::::::::::::::::::::::
XP_016 GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
             310       320       330       340       350       360 

             370       380       390       400       410       420 
pF1KSD PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
             370       380       390       400       410       420 

             430       440       450       460       470       480 
pF1KSD SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
             430       440       450       460       470       480 

             490       500       510       520       530       540 
pF1KSD MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
             490       500       510       520       530       540 

                                                                   
pF1KSD NQPQ--------------------------------------------------------
       ::::                                                        
XP_016 NQPQDKVILKTCTLTEKTSEKQNKQINRPLSCLQKMSQEPELNKECDREDVSVYSGLPCV
             550       560       570       580       590       600 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 QNDEEMWTKQGKLEWKNNLKLITNELKQSCGETCEKYKITASPGEESLHDNSKGGTNLKE
             610       620       630       640       650       660 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 IPSSLTNNILDCDEKDSPVSVLFQALPEQKVLSLENGFSFPSYSGSPEYACQSSSKPYLN
             670       680       690       700       710       720 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 ENKLGHENVNKPDTEHVFNTDENFYNDTENKKVRNPEVVTGVMKEEFDKTKNMNRNTTNW
             730       740       750       760       770       780 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 KLDIRRVPQYSDPKRPFDLICSKEMNHMFHIKRHSISAGTDAYKKTKPIQNLFQKPLYDH
             790       800       810       820       830       840 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 CSANNYKSMEPELENVRSSPPRGDRTSKVSLKEELQQDMQRFKNEIGMLKVEFQALEKEK
             850       860       870       880       890       900 

               550       560       570       580       590         
pF1KSD ------VEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLQKEVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             910       920       930       940       950       960 

     600        610       620       630       640       650        
pF1KSD NKEYAS-GPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
             970       980       990      1000      1010      1020 

      660       670       680       690       700       710        
pF1KSD EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
            1030      1040      1050      1060      1070      1080 

      720       730       740       750       760       770        
pF1KSD KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
            1090      1100      1110      1120      1130      1140 

      780       790       800       810       820       830        
pF1KSD QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
            1150      1160      1170      1180      1190      1200 

      840       850       860       870       880       890        
pF1KSD LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
            1210      1220      1230      1240      1250      1260 

      900       910       920       930       940       950        
pF1KSD NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
            1270      1280      1290      1300      1310      1320 

      960       970       980       990      1000      1010        
pF1KSD IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
            1330      1340      1350      1360      1370      1380 

     1020      1030      1040      1050      1060      1070        
pF1KSD RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
            1390      1400      1410      1420      1430      1440 

     1080      1090      1100      1110      1120      1130        
pF1KSD FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
            1450      1460      1470      1480      1490      1500 

     1140      1150      1160      1170      1180      1190        
pF1KSD QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
            1510      1520      1530      1540      1550      1560 

     1200      1210      1220      1230      1240      1250        
pF1KSD CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
            1570      1580      1590      1600      1610      1620 

     1260      1270      1280      1290      1300      1310        
pF1KSD KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
            1630      1640      1650      1660      1670      1680 

     1320      1330      1340      1350      1360      1370        
pF1KSD LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
            1690      1700      1710      1720      1730      1740 

     1380      1390      1400      1410      1420      1430        
pF1KSD GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
            1750      1760      1770      1780      1790      1800 

     1440      1450      1460      1470      1480      1490        
pF1KSD VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
            1810      1820      1830      1840      1850      1860 

     1500      1510      1520      1530      1540      1550        
pF1KSD FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
            1870      1880      1890      1900      1910      1920 

     1560      1570      1580      1590      1600      1610        
pF1KSD LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
            1930      1940      1950      1960      1970      1980 

     1620      1630      1640      1650      1660      1670        
pF1KSD DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASP
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_016 DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEGCRNGMCLQLRQC
            1990      2000      2010      2020      2030      2040 

     1680      1690      1700         
pF1KSD LGSTDESNLNQDLVWKASREYVQVLKKNYMI
                                      
XP_016 ATEKSRVMVAQRSALTEEAVA          
            2050      2060            

>--
 initn: 2140 init1: 2140 opt: 2140  Z-score: 740.4  bits: 150.3 E(85289): 1.7e-34
Smith-Waterman score: 2140; 99.7% identity (100.0% similar) in 331 aa overlap (1-331:1-331)

               10        20        30        40        50        60
pF1KSD MKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
       :::::::::::::::::::::::::::::::                             
XP_016 TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
                                                                   
XP_016 EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
              370       380       390       400       410       420

>>XP_011517718 (OMIM: 188000,610855) PREDICTED: ankyrin   (2062 aa)
 initn: 10256 init1: 6692 opt: 7047  Z-score: 2381.2  bits: 453.9 E(85289): 6.8e-126
Smith-Waterman score: 7741; 78.6% identity (78.6% similar) in 1697 aa overlap (332-1665:332-2028)

             310       320       330       340       350       360 
pF1KSD GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
                                     ::::::::::::::::::::::::::::::
XP_011 GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
             310       320       330       340       350       360 

             370       380       390       400       410       420 
pF1KSD PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
             370       380       390       400       410       420 

             430       440       450       460       470       480 
pF1KSD SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
             430       440       450       460       470       480 

             490       500       510       520       530       540 
pF1KSD MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
             490       500       510       520       530       540 

                                                                   
pF1KSD NQPQ--------------------------------------------------------
       ::::                                                        
XP_011 NQPQDKVILKTCTLTEKTSEKQNKQINRPLSCLQKMSQEPELNKECDREDVSVYSGLPCV
             550       560       570       580       590       600 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_011 QNDEEMWTKQGKLEWKNNLKLITNELKQSCGETCEKYKITASPGEESLHDNSKGGTNLKE
             610       620       630       640       650       660 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_011 IPSSLTNNILDCDEKDSPVSVLFQALPEQKVLSLENGFSFPSYSGSPEYACQSSSKPYLN
             670       680       690       700       710       720 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_011 ENKLGHENVNKPDTEHVFNTDENFYNDTENKKVRNPEVVTGVMKEEFDKTKNMNRNTTNW
             730       740       750       760       770       780 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_011 KLDIRRVPQYSDPKRPFDLICSKEMNHMFHIKRHSISAGTDAYKKTKPIQNLFQKPLYDH
             790       800       810       820       830       840 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_011 CSANNYKSMEPELENVRSSPPRGDRTSKVSLKEELQQDMQRFKNEIGMLKVEFQALEKEK
             850       860       870       880       890       900 

               550       560       570       580       590         
pF1KSD ------VEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQLQKEVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             910       920       930       940       950       960 

     600        610       620       630       640       650        
pF1KSD NKEYAS-GPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
             970       980       990      1000      1010      1020 

      660       670       680       690       700       710        
pF1KSD EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
            1030      1040      1050      1060      1070      1080 

      720       730       740       750       760       770        
pF1KSD KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
            1090      1100      1110      1120      1130      1140 

      780       790       800       810       820       830        
pF1KSD QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
            1150      1160      1170      1180      1190      1200 

      840       850       860       870       880       890        
pF1KSD LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
            1210      1220      1230      1240      1250      1260 

      900       910       920       930       940       950        
pF1KSD NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
            1270      1280      1290      1300      1310      1320 

      960       970       980       990      1000      1010        
pF1KSD IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
            1330      1340      1350      1360      1370      1380 

     1020      1030      1040      1050      1060      1070        
pF1KSD RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
            1390      1400      1410      1420      1430      1440 

     1080      1090      1100      1110      1120      1130        
pF1KSD FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
            1450      1460      1470      1480      1490      1500 

     1140      1150      1160      1170      1180      1190        
pF1KSD QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
            1510      1520      1530      1540      1550      1560 

     1200      1210      1220      1230      1240      1250        
pF1KSD CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
            1570      1580      1590      1600      1610      1620 

     1260      1270      1280      1290      1300      1310        
pF1KSD KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
            1630      1640      1650      1660      1670      1680 

     1320      1330      1340      1350      1360      1370        
pF1KSD LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
            1690      1700      1710      1720      1730      1740 

     1380      1390      1400      1410      1420      1430        
pF1KSD GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
            1750      1760      1770      1780      1790      1800 

     1440      1450      1460      1470      1480      1490        
pF1KSD VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
            1810      1820      1830      1840      1850      1860 

     1500      1510      1520      1530      1540      1550        
pF1KSD FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
            1870      1880      1890      1900      1910      1920 

     1560      1570      1580      1590      1600      1610        
pF1KSD LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
            1930      1940      1950      1960      1970      1980 

     1620      1630      1640      1650      1660      1670        
pF1KSD DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASP
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_011 DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEGCRNGMCLQLRQC
            1990      2000      2010      2020      2030      2040 

     1680      1690      1700         
pF1KSD LGSTDESNLNQDLVWKASREYVQVLKKNYMI
                                      
XP_011 ATEKSRVMVAQRSALTEEAVA          
            2050      2060            

>--
 initn: 2140 init1: 2140 opt: 2140  Z-score: 740.4  bits: 150.3 E(85289): 1.7e-34
Smith-Waterman score: 2140; 99.7% identity (100.0% similar) in 331 aa overlap (1-331:1-331)

               10        20        30        40        50        60
pF1KSD MKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_011 MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
       :::::::::::::::::::::::::::::::                             
XP_011 TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
                                                                   
XP_011 EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
              370       380       390       400       410       420

>>XP_016871420 (OMIM: 188000,610855) PREDICTED: ankyrin   (2062 aa)
 initn: 10256 init1: 6692 opt: 7047  Z-score: 2381.2  bits: 453.9 E(85289): 6.8e-126
Smith-Waterman score: 7741; 78.6% identity (78.6% similar) in 1697 aa overlap (332-1665:332-2028)

             310       320       330       340       350       360 
pF1KSD GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
                                     ::::::::::::::::::::::::::::::
XP_016 GNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKEE
             310       320       330       340       350       360 

             370       380       390       400       410       420 
pF1KSD PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWD
             370       380       390       400       410       420 

             430       440       450       460       470       480 
pF1KSD SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLEDTRNVG
             430       440       450       460       470       480 

             490       500       510       520       530       540 
pF1KSD MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSEN
             490       500       510       520       530       540 

                                                                   
pF1KSD NQPQ--------------------------------------------------------
       ::::                                                        
XP_016 NQPQDKVILKTCTLTEKTSEKQNKQINRPLSCLQKMSQEPELNKECDREDVSVYSGLPCV
             550       560       570       580       590       600 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 QNDEEMWTKQGKLEWKNNLKLITNELKQSCGETCEKYKITASPGEESLHDNSKGGTNLKE
             610       620       630       640       650       660 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 IPSSLTNNILDCDEKDSPVSVLFQALPEQKVLSLENGFSFPSYSGSPEYACQSSSKPYLN
             670       680       690       700       710       720 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 ENKLGHENVNKPDTEHVFNTDENFYNDTENKKVRNPEVVTGVMKEEFDKTKNMNRNTTNW
             730       740       750       760       770       780 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 KLDIRRVPQYSDPKRPFDLICSKEMNHMFHIKRHSISAGTDAYKKTKPIQNLFQKPLYDH
             790       800       810       820       830       840 

                                                                   
pF1KSD ------------------------------------------------------------
                                                                   
XP_016 CSANNYKSMEPELENVRSSPPRGDRTSKVSLKEELQQDMQRFKNEIGMLKVEFQALEKEK
             850       860       870       880       890       900 

               550       560       570       580       590         
pF1KSD ------VEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLQKEVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE
             910       920       930       940       950       960 

     600        610       620       630       640       650        
pF1KSD NKEYAS-GPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
       :::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDED
             970       980       990      1000      1010      1020 

      660       670       680       690       700       710        
pF1KSD EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMEC
            1030      1040      1050      1060      1070      1080 

      720       730       740       750       760       770        
pF1KSD KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEH
            1090      1100      1110      1120      1130      1140 

      780       790       800       810       820       830        
pF1KSD QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT
            1150      1160      1170      1180      1190      1200 

      840       850       860       870       880       890        
pF1KSD LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE
            1210      1220      1230      1240      1250      1260 

      900       910       920       930       940       950        
pF1KSD NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT
            1270      1280      1290      1300      1310      1320 

      960       970       980       990      1000      1010        
pF1KSD IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD
            1330      1340      1350      1360      1370      1380 

     1020      1030      1040      1050      1060      1070        
pF1KSD RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE
            1390      1400      1410      1420      1430      1440 

     1080      1090      1100      1110      1120      1130        
pF1KSD FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL
            1450      1460      1470      1480      1490      1500 

     1140      1150      1160      1170      1180      1190        
pF1KSD QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE
            1510      1520      1530      1540      1550      1560 

     1200      1210      1220      1230      1240      1250        
pF1KSD CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDL
            1570      1580      1590      1600      1610      1620 

     1260      1270      1280      1290      1300      1310        
pF1KSD KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNL
            1630      1640      1650      1660      1670      1680 

     1320      1330      1340      1350      1360      1370        
pF1KSD LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN
            1690      1700      1710      1720      1730      1740 

     1380      1390      1400      1410      1420      1430        
pF1KSD GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKT
            1750      1760      1770      1780      1790      1800 

     1440      1450      1460      1470      1480      1490        
pF1KSD VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL
            1810      1820      1830      1840      1850      1860 

     1500      1510      1520      1530      1540      1550        
pF1KSD FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY
            1870      1880      1890      1900      1910      1920 

     1560      1570      1580      1590      1600      1610        
pF1KSD LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPPCVGNLNNSL
            1930      1940      1950      1960      1970      1980 

     1620      1630      1640      1650      1660      1670        
pF1KSD DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEAAAELESGSIASP
       :::::::::::::::::::::::::::::::::::::::::::::::             
XP_016 DLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNITRELKEGCRNGMCLQLRQC
            1990      2000      2010      2020      2030      2040 

     1680      1690      1700         
pF1KSD LGSTDESNLNQDLVWKASREYVQVLKKNYMI
                                      
XP_016 ATEKSRVMVAQRSALTEEAVA          
            2050      2060            

>--
 initn: 2140 init1: 2140 opt: 2140  Z-score: 740.4  bits: 150.3 E(85289): 1.7e-34
Smith-Waterman score: 2140; 99.7% identity (100.0% similar) in 331 aa overlap (1-331:1-331)

               10        20        30        40        50        60
pF1KSD MKKIFSKKGESPLGSFARRRRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
       :::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 MKKIFSKKGESPLGSFARRQRSSAGGGGEPGEGAYSQPGYHVRDRDLGKIHKAASAGNVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KSD KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVQQILLLRKNGLNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KSD VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KSD TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQNSNSVDES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KSD SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDSLSRLSGKPGVDDSWPTSDDEDLNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KSD TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
       :::::::::::::::::::::::::::::::                             
XP_016 TGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPSHKSLANPGLMKE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KSD EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
                                                                   
XP_016 EPTKPGIAKKENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPW
              370       380       390       400       410       420




1709 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 04:53:03 2016 done: Thu Nov  3 04:53:06 2016
 Total Scan time: 20.820 Total Display time:  1.000

Function used was FASTA [36.3.4 Apr, 2011]