FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDA1036, 365 aa 1>>>pF1KSDA1036 365 - 365 aa - 365 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2752+/-0.00068; mu= 14.1166+/- 0.042 mean_var=103.4338+/-20.479, 0's: 0 Z-trim(113.6): 10 B-trim: 0 in 0/51 Lambda= 0.126108 statistics sampled from 14203 (14210) to 14203 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.437), width: 16 Scan time: 3.180 The best scores are: opt bits E(32554) CCDS9851.1 VASH1 gene_id:22846|Hs108|chr14 ( 365) 2465 458.2 5e-129 CCDS73026.1 VASH2 gene_id:79805|Hs108|chr1 ( 355) 1244 236.1 3.6e-62 CCDS44315.1 VASH2 gene_id:79805|Hs108|chr1 ( 290) 1122 213.8 1.5e-55 CCDS44316.1 VASH2 gene_id:79805|Hs108|chr1 ( 251) 998 191.2 8.2e-49 CCDS1511.1 VASH2 gene_id:79805|Hs108|chr1 ( 311) 688 134.9 9.3e-32 >>CCDS9851.1 VASH1 gene_id:22846|Hs108|chr14 (365 aa) initn: 2465 init1: 2465 opt: 2465 Z-score: 2429.9 bits: 458.2 E(32554): 5e-129 Smith-Waterman score: 2465; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365) 10 20 30 40 50 60 pF1KSD MPGGKKVAGGGSSGATPTSAAATAPSGVRRLETSEGTSAQRDEEPEEEGEEDLRDGGVPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 MPGGKKVAGGGSSGATPTSAAATAPSGVRRLETSEGTSAQRDEEPEEEGEEDLRDGGVPF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD FVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 FVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 RLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 NSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 LDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD MRLKIGKGTGPPSPTKDRKKDVSSPQRAQSSPHRRNSRSERRPSGDKKTSEPKAMPDLNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS98 MRLKIGKGTGPPSPTKDRKKDVSSPQRAQSSPHRRNSRSERRPSGDKKTSEPKAMPDLNG 310 320 330 340 350 360 pF1KSD YQIRV ::::: CCDS98 YQIRV >>CCDS73026.1 VASH2 gene_id:79805|Hs108|chr1 (355 aa) initn: 1284 init1: 1148 opt: 1244 Z-score: 1229.5 bits: 236.1 E(32554): 3.6e-62 Smith-Waterman score: 1244; 52.7% identity (77.5% similar) in 355 aa overlap (13-365:2-355) 10 20 30 40 50 60 pF1KSD MPGGKKVAGGGSSGATPTSAAATAPSGVRRLETSEGTSAQRDEEPEEEGEEDLRDGGVPF .:.. . :.:.. .. . . . .::. .:::: : CCDS73 MTGSAADTHRCPHPKGAKGTRSRSSHARPVSLATSGGSEEEDKDGGVLF 10 20 30 40 70 80 90 100 110 120 pF1KSD FVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPE ::..:.:.: :::::: ::::.:: : ... ::.:. : : ::.::... : .:. CCDS73 HVNKSGFPIDSHTWERMWMHVAKVHPKGGEMVGAIRNAAFLAKPSIPQVPNYRLSMTIPD 50 60 70 80 90 100 130 140 150 160 170 180 pF1KSD RLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLT :.:.: :.. :::::::::::::.: :::.:::. :::::.:.:::::::::::::::: CCDS73 WLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLPIKCLEAVILGIYLT 110 120 130 140 150 160 190 200 210 220 230 240 pF1KSD NSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELV :..:..::::::::::::::::.:.:::. ::::.:::::: .:: :: .:::::.:. CCDS73 NGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLI 170 180 190 200 210 220 250 260 270 280 290 300 pF1KSD LDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARD .::: .: . :..::::.: : :.::: . ::::. ::.: .. : :.:::::..::: CCDS73 FDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARD 230 240 250 260 270 280 310 320 330 340 350 pF1KSD MRLKIGKGTGPPSPTKDRKKDVS-SPQRAQSSPHRRNSRSERRPS-GDKKTSEPKAMPDL ::.:: : .. :::. :.. : ::.: :.:: :: .: :. :. .::... ... .. CCDS73 MRMKILKPASAHSPTQVRSRGKSLSPRRRQASPPRRLGRREKSPALPEKKVADLSTLNEV 290 300 310 320 330 340 360 pF1KSD NGYQIRV :::::. CCDS73 -GYQIRI 350 >>CCDS44315.1 VASH2 gene_id:79805|Hs108|chr1 (290 aa) initn: 1182 init1: 1027 opt: 1122 Z-score: 1110.8 bits: 213.8 E(32554): 1.5e-55 Smith-Waterman score: 1122; 57.7% identity (81.4% similar) in 291 aa overlap (77-365:1-290) 50 60 70 80 90 100 pF1KSD EEGEEDLRDGGVPFFVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPI :: ::::.:: : ... ::.:. : : : CCDS44 MWMHVAKVHPKGGEMVGAIRNAAFLAKPSI 10 20 30 110 120 130 140 150 160 pF1KSD PSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALP :.::... : .:. :.:.: :.. :::::::::::::.: :::.:::. :::::.:.:: CCDS44 PQVPNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKEMTRESLP 40 50 60 70 80 90 170 180 190 200 210 220 pF1KSD IKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDL :::::::::::::::..:..::::::::::::::::.:.:::. ::::.:::::: .: CCDS44 IKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAEL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KSD MYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLG : :: .:::::.:..::: .: . :..::::.: : :.::: . ::::. ::.: .. CCDS44 MDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKML 160 170 180 190 200 210 290 300 310 320 330 340 pF1KSD RDDFRKELERHARDMRLKIGKGTGPPSPTKDRKKDVS-SPQRAQSSPHRRNSRSERRPS- : :.:::::..:::::.:: : .. :::. :.. : ::.: :.:: :: .: :. :. CCDS44 RADIRKELEKYARDMRMKILKPASAHSPTQVRSRGKSLSPRRRQASPPRRLGRREKSPAL 220 230 240 250 260 270 350 360 pF1KSD GDKKTSEPKAMPDLNGYQIRV .::... ... .. :::::. CCDS44 PEKKVADLSTLNEV-GYQIRI 280 290 >>CCDS44316.1 VASH2 gene_id:79805|Hs108|chr1 (251 aa) initn: 992 init1: 856 opt: 998 Z-score: 989.8 bits: 191.2 E(32554): 8.2e-49 Smith-Waterman score: 998; 59.6% identity (83.2% similar) in 250 aa overlap (118-365:3-251) 90 100 110 120 130 140 pF1KSD GEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKS .:. :.:.: :.. :::::::::::::.: CCDS44 MTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKM 10 20 30 150 160 170 180 190 200 pF1KSD RPLTGLMDLAKEMTKEALPIKCLEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVL :::.:::. :::::.:.:::::::::::::::::..:..::::::::::::::::.:.:: CCDS44 RPLSGLMETAKEMTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVL 40 50 60 70 80 90 210 220 230 240 250 260 pF1KSD GVNFAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLGQSVSHDP :. ::::.:::::: .:: :: .:::::.:..::: .: . :..::::.: : :.: CCDS44 GIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKIGLYVPHEP 100 110 120 130 140 150 270 280 290 300 310 320 pF1KSD HSVEQIEWKHSVLDVERLGRDDFRKELERHARDMRLKIGKGTGPPSPTKDRKKDVS-SPQ :: . ::::. ::.: .. : :.:::::..:::::.:: : .. :::. :.. : ::. CCDS44 HSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMRMKILKPASAHSPTQVRSRGKSLSPR 160 170 180 190 200 210 330 340 350 360 pF1KSD RAQSSPHRRNSRSERRPS-GDKKTSEPKAMPDLNGYQIRV : :.:: :: .: :. :. .::... ... .. :::::. CCDS44 RRQASPPRRLGRREKSPALPEKKVADLSTLNEV-GYQIRI 220 230 240 250 >>CCDS1511.1 VASH2 gene_id:79805|Hs108|chr1 (311 aa) initn: 1003 init1: 593 opt: 688 Z-score: 683.7 bits: 134.9 E(32554): 9.3e-32 Smith-Waterman score: 889; 42.0% identity (65.6% similar) in 355 aa overlap (13-365:2-311) 10 20 30 40 50 60 pF1KSD MPGGKKVAGGGSSGATPTSAAATAPSGVRRLETSEGTSAQRDEEPEEEGEEDLRDGGVPF .:.. . :.:.. .. . . . .::. .:::: : CCDS15 MTGSAADTHRCPHPKGAKGTRSRSSHARPVSLATSGGSEEEDKDGGVLF 10 20 30 40 70 80 90 100 110 120 pF1KSD FVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVPTFQPSTPVPE ::..:.:.: :::::: ::::.:: : ... ::.:. : : ::.::... : .:. CCDS15 HVNKSGFPIDSHTWERMWMHVAKVHPKGGEMVGAIRNAAFLAKPSIPQVPNYRLSMTIPD 50 60 70 80 90 100 130 140 150 160 170 180 pF1KSD RLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEMTKEALPIKCLEAVILGIYLT :.:.: :.. :.: :: CCDS15 WLQAIQNYMKTLHY--------------------------------------------LT 110 120 190 200 210 220 230 240 pF1KSD NSMPTLERFPISFKTYFSGNYFRHIVLGVNFAGRYGALGMSRREDLMYKPPAFRTLSELV :..:..::::::::::::::::.:.:::. ::::.:::::: .:: :: .:::::.:. CCDS15 NGQPSIERFPISFKTYFSGNYFHHVVLGIYCNGRYGSLGMSRRAELMDKPLTFRTLSDLI 130 140 150 160 170 180 250 260 270 280 290 300 pF1KSD LDFEAAYGRCWHVLKKVKLGQSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARD .::: .: . :..::::.: : :.::: . ::::. ::.: .. : :.:::::..::: CCDS15 FDFEDSYKKYLHTVKKVKIGLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARD 190 200 210 220 230 240 310 320 330 340 350 pF1KSD MRLKIGKGTGPPSPTKDRKKDVS-SPQRAQSSPHRRNSRSERRPS-GDKKTSEPKAMPDL ::.:: : .. :::. :.. : ::.: :.:: :: .: :. :. .::... ... .. CCDS15 MRMKILKPASAHSPTQVRSRGKSLSPRRRQASPPRRLGRREKSPALPEKKVADLSTLNEV 250 260 270 280 290 300 360 pF1KSD NGYQIRV :::::. CCDS15 -GYQIRI 310 365 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 04:41:48 2016 done: Thu Nov 3 04:41:49 2016 Total Scan time: 3.180 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]