FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA1028, 502 aa
1>>>pF1KSDA1028 502 - 502 aa - 502 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.0973+/-0.00108; mu= -10.9858+/- 0.064
mean_var=503.6406+/-112.661, 0's: 0 Z-trim(115.0): 230 B-trim: 0 in 0/52
Lambda= 0.057150
statistics sampled from 15289 (15530) to 15289 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.477), width: 16
Scan time: 3.690
The best scores are: opt bits E(32554)
CCDS5085.1 CDK19 gene_id:23097|Hs108|chr6 ( 502) 3442 298.3 1.3e-80
CCDS75503.1 CDK19 gene_id:23097|Hs108|chr6 ( 442) 3042 265.3 9.9e-71
CCDS9317.1 CDK8 gene_id:1024|Hs108|chr13 ( 464) 2453 216.8 4.2e-56
>>CCDS5085.1 CDK19 gene_id:23097|Hs108|chr6 (502 aa)
initn: 3442 init1: 3442 opt: 3442 Z-score: 1560.9 bits: 298.3 E(32554): 1.3e-80
Smith-Waterman score: 3442; 100.0% identity (100.0% similar) in 502 aa overlap (1-502:1-502)
10 20 30 40 50 60
pF1KSD MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS50 AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST
430 440 450 460 470 480
490 500
pF1KSD LGYSSSSQQSSQYHPSHQAHRY
::::::::::::::::::::::
CCDS50 LGYSSSSQQSSQYHPSHQAHRY
490 500
>>CCDS75503.1 CDK19 gene_id:23097|Hs108|chr6 (442 aa)
initn: 3042 init1: 3042 opt: 3042 Z-score: 1383.3 bits: 265.3 E(32554): 9.9e-71
Smith-Waterman score: 3042; 100.0% identity (100.0% similar) in 442 aa overlap (61-502:1-442)
40 50 60 70 80 90
pF1KSD TYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSD
::::::::::::::::::::::::::::::
CCDS75 MSACREIALLRELKHPNVIALQKVFLSHSD
10 20 30
100 110 120 130 140 150
pF1KSD RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KSD DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH
100 110 120 130 140 150
220 230 240 250 260 270
pF1KSD YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 YTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDI
160 170 180 190 200 210
280 290 300 310 320 330
pF1KSD RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 RKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQAL
220 230 240 250 260 270
340 350 360 370 380 390
pF1KSD QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 QDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KSD APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 APPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSG
340 350 360 370 380 390
460 470 480 490 500
pF1KSD GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 GPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
400 410 420 430 440
>>CCDS9317.1 CDK8 gene_id:1024|Hs108|chr13 (464 aa)
initn: 2629 init1: 2400 opt: 2453 Z-score: 1120.6 bits: 216.8 E(32554): 4.2e-56
Smith-Waterman score: 2585; 77.7% identity (87.1% similar) in 502 aa overlap (1-502:1-464)
10 20 30 40 50 60
pF1KSD MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
::::::.::..:::::::::::::::::::::::::::.::::::.:.::::::::::::
CCDS93 MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
:::::::::::::::::::.::::::::.:::::::::::::::::::::::::::::::
CCDS93 MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
.::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS93 VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS93 NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
::::::.:::::::::.:::::::::::::.::::. ::.:::::.::.: :::::::::
CCDS93 IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
:::::::.: :::::::::: ::::::::.::::: :::::: ::::::::::::::::.
CCDS93 KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG
:..:..::::..:::: :....:::: : :
CCDS93 EEEPDDKGDKKNQQQQ-----------------------QGNNHTNGT-GHPG-------
370 380
430 440 450 460 470 480
pF1KSD AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST
.:::: .: :: :: :. : ..::: .: ::::.:. . : . ..:: ::.
CCDS93 -----NQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSS
390 400 410 420 430 440
490 500
pF1KSD LGYSSSSQQSSQYHPSHQAHRY
.:::..::: :: :::.:::
CCDS93 MGYSATSQQPPQY--SHQTHRY
450 460
502 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:16:09 2016 done: Fri Nov 4 00:16:10 2016
Total Scan time: 3.690 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]