Result of FASTA (omim) for
pF1KSDA0957
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0957, 692 aa
1>>>pF1KSDA0957 692 - 692 aa - 692 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8574+/-0.000455; mu= 4.2472+/- 0.028
mean_var=254.7418+/-53.246, 0's: 0 Z-trim(119.6): 674 B-trim: 1017 in 1/52
Lambda= 0.080357
statistics sampled from 33001 (33805) to 33001 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.396), width: 16
Scan time: 9.610
The best scores are: opt bits E(85289)
NP_001229742 (OMIM: 610583) ankyrin repeat domain- ( 692) 4525 538.4 3.4e-152
XP_016865987 (OMIM: 610583) PREDICTED: ankyrin rep ( 687) 4476 532.7 1.7e-150
XP_016865982 (OMIM: 610583) PREDICTED: ankyrin rep ( 717) 4064 485.0 4.3e-136
XP_016865984 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 4029 480.9 7e-135
XP_016865986 (OMIM: 610583) PREDICTED: ankyrin rep ( 689) 3980 475.2 3.5e-133
XP_016865994 (OMIM: 610583) PREDICTED: ankyrin rep ( 659) 3784 452.5 2.4e-126
XP_011533901 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 3757 449.4 2.2e-125
XP_016865991 (OMIM: 610583) PREDICTED: ankyrin rep ( 661) 3586 429.5 1.9e-119
XP_011533898 (OMIM: 610583) PREDICTED: ankyrin rep ( 719) 3568 427.5 8.7e-119
XP_016865983 (OMIM: 610583) PREDICTED: ankyrin rep ( 714) 3519 421.8 4.5e-117
XP_016865993 (OMIM: 610583) PREDICTED: ankyrin rep ( 659) 3505 420.1 1.3e-116
XP_016865985 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 3433 411.8 4.4e-114
XP_011533900 (OMIM: 610583) PREDICTED: ankyrin rep ( 694) 3433 411.8 4.4e-114
XP_016865988 (OMIM: 610583) PREDICTED: ankyrin rep ( 684) 3410 409.1 2.8e-113
XP_016865998 (OMIM: 610583) PREDICTED: ankyrin rep ( 626) 3372 404.7 5.5e-112
XP_016866000 (OMIM: 610583) PREDICTED: ankyrin rep ( 593) 3328 399.6 1.8e-110
XP_016865999 (OMIM: 610583) PREDICTED: ankyrin rep ( 593) 3328 399.6 1.8e-110
XP_016865992 (OMIM: 610583) PREDICTED: ankyrin rep ( 661) 3314 398.0 6e-110
XP_011533899 (OMIM: 610583) PREDICTED: ankyrin rep ( 719) 3296 396.0 2.7e-109
XP_016865996 (OMIM: 610583) PREDICTED: ankyrin rep ( 656) 3239 389.3 2.5e-107
NP_001229740 (OMIM: 610583) ankyrin repeat domain- ( 727) 3229 388.2 6e-107
NP_001229738 (OMIM: 610583) ankyrin repeat domain- ( 727) 3229 388.2 6e-107
XP_005248738 (OMIM: 610583) PREDICTED: ankyrin rep ( 727) 3229 388.2 6e-107
XP_005248736 (OMIM: 610583) PREDICTED: ankyrin rep ( 752) 3208 385.8 3.3e-106
XP_016865990 (OMIM: 610583) PREDICTED: ankyrin rep ( 661) 3162 380.4 1.2e-104
XP_005248737 (OMIM: 610583) PREDICTED: ankyrin rep ( 747) 3159 380.1 1.7e-104
XP_016865995 (OMIM: 610583) PREDICTED: ankyrin rep ( 656) 3113 374.7 6.2e-103
XP_016865997 (OMIM: 610583) PREDICTED: ankyrin rep ( 628) 3083 371.2 6.7e-102
XP_005248740 (OMIM: 610583) PREDICTED: ankyrin rep ( 686) 3067 369.4 2.6e-101
XP_016865989 (OMIM: 610583) PREDICTED: ankyrin rep ( 681) 3018 363.7 1.3e-99
XP_016866002 (OMIM: 610583) PREDICTED: ankyrin rep ( 567) 2986 359.9 1.5e-98
XP_016866001 (OMIM: 610583) PREDICTED: ankyrin rep ( 567) 2986 359.9 1.5e-98
XP_005248741 (OMIM: 610583) PREDICTED: ankyrin rep ( 592) 2911 351.2 6.5e-96
XP_016866003 (OMIM: 610583) PREDICTED: ankyrin rep ( 534) 2901 350.0 1.3e-95
XP_016866004 (OMIM: 610583) PREDICTED: ankyrin rep ( 493) 2851 344.2 7e-94
XP_005248739 (OMIM: 610583) PREDICTED: ankyrin rep ( 726) 2842 343.3 1.9e-93
XP_011533902 (OMIM: 610583) PREDICTED: ankyrin rep ( 663) 2793 337.6 9.2e-92
NP_001229743 (OMIM: 610583) ankyrin repeat domain- ( 663) 2793 337.6 9.2e-92
NP_055757 (OMIM: 610583) ankyrin repeat domain-con ( 722) 1746 216.3 3.4e-55
XP_016863596 (OMIM: 106410,600919) PREDICTED: anky (1797) 466 68.3 3e-10
XP_016863595 (OMIM: 106410,600919) PREDICTED: anky (1806) 466 68.3 3e-10
XP_016863591 (OMIM: 106410,600919) PREDICTED: anky (1838) 466 68.3 3.1e-10
XP_016863589 (OMIM: 106410,600919) PREDICTED: anky (1846) 466 68.3 3.1e-10
XP_016863586 (OMIM: 106410,600919) PREDICTED: anky (1858) 466 68.3 3.1e-10
XP_016863580 (OMIM: 106410,600919) PREDICTED: anky (1879) 466 68.3 3.1e-10
XP_011517331 (OMIM: 607001,610253) PREDICTED: hist ( 775) 451 66.2 5.5e-10
NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform (1719) 456 67.1 6.5e-10
XP_011542807 (OMIM: 182900,612641) PREDICTED: anky (1751) 456 67.1 6.6e-10
XP_011542806 (OMIM: 182900,612641) PREDICTED: anky (1752) 456 67.1 6.6e-10
XP_016868818 (OMIM: 182900,612641) PREDICTED: anky (1759) 456 67.1 6.6e-10
>>NP_001229742 (OMIM: 610583) ankyrin repeat domain-cont (692 aa)
initn: 4525 init1: 4525 opt: 4525 Z-score: 2853.4 bits: 538.4 E(85289): 3.4e-152
Smith-Waterman score: 4525; 99.9% identity (100.0% similar) in 692 aa overlap (1-692:1-692)
10 20 30 40 50 60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
610 620 630 640 650 660
670 680 690
pF1KSD QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
::::::::::::::::::::::::::::::::
NP_001 QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
670 680 690
>>XP_016865987 (OMIM: 610583) PREDICTED: ankyrin repeat (687 aa)
initn: 3274 init1: 3274 opt: 4476 Z-score: 2822.7 bits: 532.7 E(85289): 1.7e-150
Smith-Waterman score: 4476; 99.1% identity (99.3% similar) in 692 aa overlap (1-692:1-687)
10 20 30 40 50 60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD KLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_016 KLSGDSRACRAKSTPSTC-----VDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
490 500 510 520 530
550 560 570 580 590 600
pF1KSD QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KSD PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
600 610 620 630 640 650
670 680 690
pF1KSD QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
::::::::::::::::::::::::::::::::
XP_016 QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
660 670 680
>>XP_016865982 (OMIM: 610583) PREDICTED: ankyrin repeat (717 aa)
initn: 4064 init1: 4064 opt: 4064 Z-score: 2564.3 bits: 485.0 E(85289): 4.3e-136
Smith-Waterman score: 4064; 99.4% identity (99.8% similar) in 622 aa overlap (71-692:96-717)
50 60 70 80 90 100
pF1KSD HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA
. .:::::::::::::::::::::::::::
XP_016 AVATVKAMKEDKNKKNHRGKVRKDPRRSEREKEGDQTALHRATVVGNTEIIAALIHEGCA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 LDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD LLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD RKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRN
310 320 330 340 350 360
350 360 370 380 390 400
pF1KSD RHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAE
370 380 390 400 410 420
410 420 430 440 450 460
pF1KSD LGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQ
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD ISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSS
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD PPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVN
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD RGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAV
610 620 630 640 650 660
650 660 670 680 690
pF1KSD STQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
670 680 690 700 710
>>XP_016865984 (OMIM: 610583) PREDICTED: ankyrin repeat (694 aa)
initn: 4055 init1: 2842 opt: 4029 Z-score: 2542.6 bits: 480.9 E(85289): 7e-135
Smith-Waterman score: 4149; 90.5% identity (90.6% similar) in 727 aa overlap (1-692:1-694)
10 20 30 40 50 60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDT----
130 140 150 160 170
190 200 210 220 230 240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
:::::::::::::::::::::::::::::::
XP_016 -----------------------------ALHVAAALNHKKVAKILLEAGADTTIVNNAG
180 190 200
250 260
pF1KSD QTPLETARYHNNPEVALLLTKAPQ-----------------------------------G
:::::::::::::::::::::::: :
XP_016 QTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKG
210 220 230 240 250 260
270 280 290 300 310 320
pF1KSD SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
270 280 290 300 310 320
330 340 350 360 370 380
pF1KSD HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
330 340 350 360 370 380
390 400 410 420 430 440
pF1KSD LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
390 400 410 420 430 440
450 460 470 480 490 500
pF1KSD QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
450 460 470 480 490 500
510 520 530 540 550 560
pF1KSD QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
510 520 530 540 550 560
570 580 590 600 610 620
pF1KSD NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
570 580 590 600 610 620
630 640 650 660 670 680
pF1KSD TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
630 640 650 660 670 680
690
pF1KSD TRVQKEN
:::::::
XP_016 TRVQKEN
690
>>XP_016865986 (OMIM: 610583) PREDICTED: ankyrin repeat (689 aa)
initn: 2804 init1: 1591 opt: 3980 Z-score: 2511.9 bits: 475.2 E(85289): 3.5e-133
Smith-Waterman score: 4100; 89.8% identity (90.0% similar) in 727 aa overlap (1-692:1-689)
10 20 30 40 50 60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDT----
130 140 150 160 170
190 200 210 220 230 240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
:::::::::::::::::::::::::::::::
XP_016 -----------------------------ALHVAAALNHKKVAKILLEAGADTTIVNNAG
180 190 200
250 260
pF1KSD QTPLETARYHNNPEVALLLTKAPQ-----------------------------------G
:::::::::::::::::::::::: :
XP_016 QTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKG
210 220 230 240 250 260
270 280 290 300 310 320
pF1KSD SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
270 280 290 300 310 320
330 340 350 360 370 380
pF1KSD HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
330 340 350 360 370 380
390 400 410 420 430 440
pF1KSD LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
390 400 410 420 430 440
450 460 470 480 490 500
pF1KSD QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTC-----VD
450 460 470 480 490 500
510 520 530 540 550 560
pF1KSD QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
510 520 530 540 550 560
570 580 590 600 610 620
pF1KSD NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
570 580 590 600 610 620
630 640 650 660 670 680
pF1KSD TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
630 640 650 660 670 680
690
pF1KSD TRVQKEN
:::::::
XP_016 TRVQKEN
>>XP_016865994 (OMIM: 610583) PREDICTED: ankyrin repeat (659 aa)
initn: 3756 init1: 3756 opt: 3784 Z-score: 2389.4 bits: 452.5 E(85289): 2.4e-126
Smith-Waterman score: 4237; 95.2% identity (95.2% similar) in 692 aa overlap (1-692:1-659)
10 20 30 40 50 60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDK--------------
70 80 90 100
130 140 150 160 170 180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
:::::::::::::::::::::::::::::::::::::::::
XP_016 -------------------AGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
110 120 130 140
190 200 210 220 230 240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
150 160 170 180 190 200
250 260 270 280 290 300
pF1KSD QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTPLETARYHNNPEVALLLTKAPQGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD
210 220 230 240 250 260
310 320 330 340 350 360
pF1KSD DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYT
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQ
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQ
390 400 410 420 430 440
490 500 510 520 530 540
pF1KSD KLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSGDSRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQ
450 460 470 480 490 500
550 560 570 580 590 600
pF1KSD QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QELSSSDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQ
510 520 530 540 550 560
610 620 630 640 650 660
pF1KSD PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQAN
570 580 590 600 610 620
670 680 690
pF1KSD QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
::::::::::::::::::::::::::::::::
XP_016 QKAQQDKATLKEHIKSLEEELAKLRTRVQKEN
630 640 650
>>XP_011533901 (OMIM: 610583) PREDICTED: ankyrin repeat (694 aa)
initn: 3783 init1: 2842 opt: 3757 Z-score: 2372.2 bits: 449.4 E(85289): 2.2e-125
Smith-Waterman score: 4157; 90.6% identity (90.6% similar) in 727 aa overlap (1-692:1-694)
10 20 30 40 50 60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDK--------------
70 80 90 100
130 140 150 160 170 180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
:::::::::::::::::::::::::::::::::::::::::
XP_011 -------------------AGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
110 120 130 140
190 200 210 220 230 240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
150 160 170 180 190 200
250 260
pF1KSD QTPLETARYHNNPEVALLLTKAPQ-----------------------------------G
:::::::::::::::::::::::: :
XP_011 QTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKG
210 220 230 240 250 260
270 280 290 300 310 320
pF1KSD SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
270 280 290 300 310 320
330 340 350 360 370 380
pF1KSD HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
330 340 350 360 370 380
390 400 410 420 430 440
pF1KSD LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
390 400 410 420 430 440
450 460 470 480 490 500
pF1KSD QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
450 460 470 480 490 500
510 520 530 540 550 560
pF1KSD QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
510 520 530 540 550 560
570 580 590 600 610 620
pF1KSD NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
570 580 590 600 610 620
630 640 650 660 670 680
pF1KSD TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
630 640 650 660 670 680
690
pF1KSD TRVQKEN
:::::::
XP_011 TRVQKEN
690
>>XP_016865991 (OMIM: 610583) PREDICTED: ankyrin repeat (661 aa)
initn: 3591 init1: 2842 opt: 3586 Z-score: 2265.3 bits: 429.5 E(85289): 1.9e-119
Smith-Waterman score: 3844; 86.0% identity (86.1% similar) in 727 aa overlap (1-692:1-661)
10 20 30 40 50 60
pF1KSD MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQI
::::::::::::::::::::::::::::::::::::::::
XP_016 MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTK--------------------
10 20 30 40
70 80 90 100 110 120
pF1KSD LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------------GDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGF
50 60 70 80
130 140 150 160 170 180
pF1KSD SQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHV
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDT----
90 100 110 120 130 140
190 200 210 220 230 240
pF1KSD AARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAG
:::::::::::::::::::::::::::::::
XP_016 -----------------------------ALHVAAALNHKKVAKILLEAGADTTIVNNAG
150 160 170
250 260
pF1KSD QTPLETARYHNNPEVALLLTKAPQ-----------------------------------G
:::::::::::::::::::::::: :
XP_016 QTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKG
180 190 200 210 220 230
270 280 290 300 310 320
pF1KSD SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPG
240 250 260 270 280 290
330 340 350 360 370 380
pF1KSD HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINK
300 310 320 330 340 350
390 400 410 420 430 440
pF1KSD LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRL
360 370 380 390 400 410
450 460 470 480 490 500
pF1KSD QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGDSRACRAKSTPSTCESSTGVD
420 430 440 450 460 470
510 520 530 540 550 560
pF1KSD QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPM
480 490 500 510 520 530
570 580 590 600 610 620
pF1KSD NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASSTCGQPPPATGSEQTGPHIRD
540 550 560 570 580 590
630 640 650 660 670 680
pF1KSD TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLR
600 610 620 630 640 650
690
pF1KSD TRVQKEN
:::::::
XP_016 TRVQKEN
660
>>XP_011533898 (OMIM: 610583) PREDICTED: ankyrin repeat (719 aa)
initn: 3594 init1: 2842 opt: 3568 Z-score: 2253.6 bits: 427.5 E(85289): 8.7e-119
Smith-Waterman score: 3688; 89.0% identity (89.5% similar) in 657 aa overlap (71-692:96-719)
50 60 70 80 90 100
pF1KSD HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA
. .:::::::::::::::::::::::::::
XP_011 AVATVKAMKEDKNKKNHRGKVRKDPRRSEREKEGDQTALHRATVVGNTEIIAALIHEGCA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_011 LDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD LLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHK
:::::::::::::::: :::::::::::
XP_011 LLAGSRADLKNNAGDT---------------------------------ALHVAAALNHK
190 200 210
230 240 250 260
pF1KSD KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQ----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRER
220 230 240 250 260 270
270 280 290 300
pF1KSD -------------------GSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRK
:::::::::::::::::::::::::::::::::::::::::
XP_011 LKEERRAQSVPRDEVAQSKGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRK
280 290 300 310 320 330
310 320 330 340 350 360
pF1KSD SRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGK
340 350 360 370 380 390
370 380 390 400 410 420
pF1KSD DGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRV
400 410 420 430 440 450
430 440 450 460 470 480
pF1KSD LDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGD
460 470 480 490 500 510
490 500 510 520 530 540
pF1KSD SRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSS
520 530 540 550 560 570
550 560 570 580 590 600
pF1KSD SDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASS
580 590 600 610 620 630
610 620 630 640 650 660
pF1KSD TCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQ
640 650 660 670 680 690
670 680 690
pF1KSD DKATLKEHIKSLEEELAKLRTRVQKEN
:::::::::::::::::::::::::::
XP_011 DKATLKEHIKSLEEELAKLRTRVQKEN
700 710
>>XP_016865983 (OMIM: 610583) PREDICTED: ankyrin repeat (714 aa)
initn: 2343 init1: 1591 opt: 3519 Z-score: 2222.9 bits: 421.8 E(85289): 4.5e-117
Smith-Waterman score: 3639; 88.3% identity (88.7% similar) in 657 aa overlap (71-692:96-714)
50 60 70 80 90 100
pF1KSD HGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCA
. .:::::::::::::::::::::::::::
XP_016 AVATVKAMKEDKNKKNHRGKVRKDPRRSEREKEGDQTALHRATVVGNTEIIAALIHEGCA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD LDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 LDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD LLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHK
:::::::::::::::: :::::::::::
XP_016 LLAGSRADLKNNAGDT---------------------------------ALHVAAALNHK
190 200 210
230 240 250 260
pF1KSD KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQ----------------
::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRER
220 230 240 250 260 270
270 280 290 300
pF1KSD -------------------GSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRK
:::::::::::::::::::::::::::::::::::::::::
XP_016 LKEERRAQSVPRDEVAQSKGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRK
280 290 300 310 320 330
310 320 330 340 350 360
pF1KSD SRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGK
340 350 360 370 380 390
370 380 390 400 410 420
pF1KSD DGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRV
400 410 420 430 440 450
430 440 450 460 470 480
pF1KSD LDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDKLMVERLSAERTECLNRLQQHSDTEKHEGEKRQISLVDELKTWCMLKIQNLEQKLSGD
460 470 480 490 500 510
490 500 510 520 530 540
pF1KSD SRACRAKSTPSTCESSTGVDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSS
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_016 SRACRAKSTPSTC-----VDQLVVTAGPAAASDSSPPVVRPKEKALNSTATQRLQQELSS
520 530 540 550 560
550 560 570 580 590 600
pF1KSD SDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDCTGSRLRNVKVQTALLPMNEAARSDQQAGPCVNRGTQTKKSGKSGPTRHRAQQPAASS
570 580 590 600 610 620
610 620 630 640 650 660
pF1KSD TCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQ
630 640 650 660 670 680
670 680 690
pF1KSD DKATLKEHIKSLEEELAKLRTRVQKEN
:::::::::::::::::::::::::::
XP_016 DKATLKEHIKSLEEELAKLRTRVQKEN
690 700 710
692 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 04:24:12 2016 done: Thu Nov 3 04:24:13 2016
Total Scan time: 9.610 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]