Result of FASTA (omim) for
pF1KSDA0934
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0934, 1556 aa
1>>>pF1KSDA0934 1556 - 1556 aa - 1556 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4168+/-0.000489; mu= 12.6809+/- 0.030
mean_var=119.7523+/-25.562, 0's: 0 Z-trim(112.0): 87 B-trim: 860 in 1/49
Lambda= 0.117201
statistics sampled from 20685 (20764) to 20685 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.243), width: 16
Scan time: 16.770
The best scores are: opt bits E(85289)
NP_055789 (OMIM: 611380) disco-interacting protein (1556) 10431 1776.4 0
XP_011517733 (OMIM: 611380) PREDICTED: disco-inter (1560) 10264 1748.2 0
XP_005252483 (OMIM: 611380) PREDICTED: disco-inter (1612) 10093 1719.3 0
XP_011517731 (OMIM: 611380) PREDICTED: disco-inter (1616) 10093 1719.3 0
XP_005252484 (OMIM: 611380) PREDICTED: disco-inter (1566) 8791 1499.2 0
XP_011517732 (OMIM: 611380) PREDICTED: disco-inter (1570) 8624 1470.9 0
XP_005252485 (OMIM: 611380) PREDICTED: disco-inter (1622) 8453 1442.0 0
XP_011517730 (OMIM: 611380) PREDICTED: disco-inter (1626) 8453 1442.0 0
XP_011517734 (OMIM: 611380) PREDICTED: disco-inter (1459) 8102 1382.6 0
XP_016875190 (OMIM: 136630,611379) PREDICTED: disc (1570) 7811 1333.4 0
NP_001139588 (OMIM: 607711) disco-interacting prot (1567) 7767 1326.0 0
NP_775873 (OMIM: 136630,611379) disco-interacting (1576) 7653 1306.7 0
XP_016875189 (OMIM: 136630,611379) PREDICTED: disc (1571) 7585 1295.2 0
XP_006719583 (OMIM: 136630,611379) PREDICTED: disc (1586) 7580 1294.4 0
XP_016883786 (OMIM: 607711) PREDICTED: disco-inter (1563) 7518 1283.9 0
XP_016875188 (OMIM: 136630,611379) PREDICTED: disc (1581) 7507 1282.0 0
XP_016883784 (OMIM: 607711) PREDICTED: disco-inter (1571) 7472 1276.1 0
NP_055966 (OMIM: 607711) disco-interacting protein (1571) 7472 1276.1 0
XP_016883785 (OMIM: 607711) PREDICTED: disco-inter (1571) 7472 1276.1 0
XP_016883783 (OMIM: 607711) PREDICTED: disco-inter (1572) 7463 1274.6 0
XP_016883782 (OMIM: 607711) PREDICTED: disco-inter (1606) 7461 1274.3 0
XP_016883781 (OMIM: 607711) PREDICTED: disco-inter (1607) 7457 1273.6 0
XP_011527794 (OMIM: 607711) PREDICTED: disco-inter (1607) 7457 1273.6 0
XP_016883780 (OMIM: 607711) PREDICTED: disco-inter (1607) 7457 1273.6 0
XP_016883791 (OMIM: 607711) PREDICTED: disco-inter (1487) 7392 1262.6 0
XP_016883788 (OMIM: 607711) PREDICTED: disco-inter (1522) 7392 1262.6 0
XP_016883787 (OMIM: 607711) PREDICTED: disco-inter (1528) 7271 1242.1 0
XP_005269101 (OMIM: 136630,611379) PREDICTED: disc (1577) 7217 1233.0 0
XP_011536896 (OMIM: 136630,611379) PREDICTED: disc (1587) 7214 1232.5 0
XP_006719584 (OMIM: 136630,611379) PREDICTED: disc (1515) 7170 1225.1 0
XP_016875193 (OMIM: 136630,611379) PREDICTED: disc (1505) 7160 1223.4 0
XP_011536898 (OMIM: 136630,611379) PREDICTED: disc (1516) 7157 1222.9 0
XP_016875192 (OMIM: 136630,611379) PREDICTED: disc (1506) 7147 1221.2 0
XP_016875194 (OMIM: 136630,611379) PREDICTED: disc (1499) 7100 1213.2 0
XP_016883792 (OMIM: 607711) PREDICTED: disco-inter (1478) 6243 1068.3 0
XP_016883790 (OMIM: 607711) PREDICTED: disco-inter (1490) 6243 1068.3 0
XP_016883789 (OMIM: 607711) PREDICTED: disco-inter (1515) 6243 1068.3 0
XP_016883793 (OMIM: 607711) PREDICTED: disco-inter (1381) 6110 1045.8 0
XP_005252487 (OMIM: 611380) PREDICTED: disco-inter ( 993) 5978 1023.4 0
XP_016875191 (OMIM: 136630,611379) PREDICTED: disc (1520) 5435 931.7 0
XP_011536897 (OMIM: 136630,611379) PREDICTED: disc (1531) 5435 931.7 0
XP_011527803 (OMIM: 607711) PREDICTED: disco-inter (1210) 5065 869.1 0
XP_016871466 (OMIM: 611380) PREDICTED: disco-inter (1003) 4338 746.1 3.3e-214
XP_011517735 (OMIM: 611380) PREDICTED: disco-inter ( 887) 4230 727.8 9.3e-209
NP_996772 (OMIM: 607711) disco-interacting protein ( 889) 3468 599.0 5.7e-170
NP_996773 (OMIM: 607711) disco-interacting protein ( 841) 3239 560.3 2.5e-158
XP_011527804 (OMIM: 607711) PREDICTED: disco-inter ( 881) 3218 556.7 3e-157
XP_016883794 (OMIM: 607711) PREDICTED: disco-inter ( 881) 3218 556.7 3e-157
NP_001139587 (OMIM: 607711) disco-interacting prot ( 798) 3038 526.3 4e-148
NP_996774 (OMIM: 607711) disco-interacting protein ( 812) 3004 520.5 2.2e-146
>>NP_055789 (OMIM: 611380) disco-interacting protein 2 h (1556 aa)
initn: 10431 init1: 10431 opt: 10431 Z-score: 9531.6 bits: 1776.4 E(85289): 0
Smith-Waterman score: 10431; 100.0% identity (100.0% similar) in 1556 aa overlap (1-1556:1-1556)
10 20 30 40 50 60
pF1KSD MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQALPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQALPQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD ERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD VQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD TQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD QMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD DAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD RDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD DFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD VAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD VGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD LFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD EDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLME
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD SACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD VSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD QSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD RTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTVYV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD DMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAH
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD NASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD GALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550
pF1KSD LVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
1510 1520 1530 1540 1550
>>XP_011517733 (OMIM: 611380) PREDICTED: disco-interacti (1560 aa)
initn: 10264 init1: 10264 opt: 10264 Z-score: 9379.0 bits: 1748.2 E(85289): 0
Smith-Waterman score: 10264; 100.0% identity (100.0% similar) in 1528 aa overlap (29-1556:33-1560)
10 20 30 40 50
pF1KSD MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQAL
::::::::::::::::::::::::::::::
XP_011 CGVLWWTRATGRGVARWRRGAGRSVLWWMRGDITQKGYEKKRSKLIGAYLPQPPRVDQAL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD PQERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD LVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD SSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD AELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD GAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD SMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD RKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD PPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVN
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD VLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHW
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD ALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEAL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD TVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKP
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD DGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLL
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD GFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD RIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSET
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD KQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLG
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD QIEDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIEDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVML
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KSD MERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEV
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KSD SRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLD
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KSD FSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KSD GHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLS
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KSD RVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTV
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KSD YVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHS
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KSD AHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALY
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KSD VVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDL
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KSD VPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
1510 1520 1530 1540 1550 1560
>>XP_005252483 (OMIM: 611380) PREDICTED: disco-interacti (1612 aa)
initn: 10093 init1: 10093 opt: 10093 Z-score: 9222.5 bits: 1719.3 E(85289): 0
Smith-Waterman score: 10156; 96.4% identity (96.4% similar) in 1588 aa overlap (25-1556:25-1612)
10 20 30 40 50
pF1KSD MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPR-------
::::::::::::::::::::::::::::
XP_005 MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPTANGAAVV
10 20 30 40 50 60
60
pF1KSD -------------------------------------------------VDQALPQERRA
:::::::::::
XP_005 RCRLQHSEGAPRRTFRSAHIGVCDVREAAARERVASTAGNRPLFYFRFGVDQALPQERRA
70 80 90 100 110 120
70 80 90 100 110 120
pF1KSD PVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTS
130 140 150 160 170 180
130 140 150 160 170 180
pF1KSD MDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSG
190 200 210 220 230 240
190 200 210 220 230 240
pF1KSD GSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMET
250 260 270 280 290 300
250 260 270 280 290 300
pF1KSD GDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLA
310 320 330 340 350 360
310 320 330 340 350 360
pF1KSD MRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAY
370 380 390 400 410 420
370 380 390 400 410 420
pF1KSD SILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDAGS
430 440 450 460 470 480
430 440 450 460 470 480
pF1KSD QQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWF
490 500 510 520 530 540
490 500 510 520 530 540
pF1KSD PHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDFKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDFKK
550 560 570 580 590 600
550 560 570 580 590 600
pF1KSD DVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHR
610 620 630 640 650 660
610 620 630 640 650 660
pF1KSD DQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRR
670 680 690 700 710 720
670 680 690 700 710 720
pF1KSD PTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVPQL
730 740 750 760 770 780
730 740 750 760 770 780
pF1KSD CRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVGPG
790 800 810 820 830 840
790 800 810 820 830 840
pF1KSD GLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVIVA
850 860 870 880 890 900
850 860 870 880 890 900
pF1KSD EQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLE
910 920 930 940 950 960
910 920 930 940 950 960
pF1KSD GSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDND
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KSD QARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERGHL
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KSD QDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACL
1090 1100 1110 1120 1130 1140
1090 1100 1110 1120 1130 1140
pF1KSD MTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVSTT
1150 1160 1170 1180 1190 1200
1150 1160 1170 1180 1190 1200
pF1KSD GMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSIL
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KSD IPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCV
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KSD VVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTVYVDMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTVYVDMRA
1330 1340 1350 1360 1370 1380
1330 1340 1350 1360 1370 1380
pF1KSD LRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNASG
1390 1400 1410 1420 1430 1440
1390 1400 1410 1420 1430 1440
pF1KSD YFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALD
1450 1460 1470 1480 1490 1500
1450 1460 1470 1480 1490 1500
pF1KSD EAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVPLVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVPLVTN
1510 1520 1530 1540 1550 1560
1510 1520 1530 1540 1550
pF1KSD VVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
1570 1580 1590 1600 1610
>>XP_011517731 (OMIM: 611380) PREDICTED: disco-interacti (1616 aa)
initn: 10093 init1: 10093 opt: 10093 Z-score: 9222.5 bits: 1719.3 E(85289): 0
Smith-Waterman score: 10134; 96.4% identity (96.4% similar) in 1584 aa overlap (29-1556:33-1616)
10 20 30 40 50
pF1KSD MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPR-----
::::::::::::::::::::::::
XP_011 CGVLWWTRATGRGVARWRRGAGRSVLWWMRGDITQKGYEKKRSKLIGAYLPQPPTANGAA
10 20 30 40 50 60
60
pF1KSD ---------------------------------------------------VDQALPQER
:::::::::
XP_011 VVRCRLQHSEGAPRRTFRSAHIGVCDVREAAARERVASTAGNRPLFYFRFGVDQALPQER
70 80 90 100 110 120
70 80 90 100 110 120
pF1KSD RAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQ
130 140 150 160 170 180
130 140 150 160 170 180
pF1KSD TSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQ
190 200 210 220 230 240
190 200 210 220 230 240
pF1KSD SGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELM
250 260 270 280 290 300
250 260 270 280 290 300
pF1KSD ETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQM
310 320 330 340 350 360
310 320 330 340 350 360
pF1KSD LAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKV
370 380 390 400 410 420
370 380 390 400 410 420
pF1KSD AYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDA
430 440 450 460 470 480
430 440 450 460 470 480
pF1KSD GSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRD
490 500 510 520 530 540
490 500 510 520 530 540
pF1KSD WFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDF
550 560 570 580 590 600
550 560 570 580 590 600
pF1KSD KKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVA
610 620 630 640 650 660
610 620 630 640 650 660
pF1KSD HRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAI
670 680 690 700 710 720
670 680 690 700 710 720
pF1KSD RRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVP
730 740 750 760 770 780
730 740 750 760 770 780
pF1KSD QLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVG
790 800 810 820 830 840
790 800 810 820 830 840
pF1KSD PGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVI
850 860 870 880 890 900
850 860 870 880 890 900
pF1KSD VAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLF
910 920 930 940 950 960
910 920 930 940 950 960
pF1KSD LEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIED
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KSD NDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERG
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KSD HLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSA
1090 1100 1110 1120 1130 1140
1090 1100 1110 1120 1130 1140
pF1KSD CLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVS
1150 1160 1170 1180 1190 1200
1150 1160 1170 1180 1190 1200
pF1KSD TTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQS
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KSD ILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRT
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KSD CVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTVYVDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTTVYVDM
1330 1340 1350 1360 1370 1380
1330 1340 1350 1360 1370 1380
pF1KSD RALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNA
1390 1400 1410 1420 1430 1440
1390 1400 1410 1420 1430 1440
pF1KSD SGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGA
1450 1460 1470 1480 1490 1500
1450 1460 1470 1480 1490 1500
pF1KSD LDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVPLV
1510 1520 1530 1540 1550 1560
1510 1520 1530 1540 1550
pF1KSD TNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
1570 1580 1590 1600 1610
>>XP_005252484 (OMIM: 611380) PREDICTED: disco-interacti (1566 aa)
initn: 8791 init1: 8791 opt: 8791 Z-score: 8032.9 bits: 1499.2 E(85289): 0
Smith-Waterman score: 10401; 99.4% identity (99.4% similar) in 1566 aa overlap (1-1556:1-1566)
10 20 30 40 50 60
pF1KSD MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQALPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQALPQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD ERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD VQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD TQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD LMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD QMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD KVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD DAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD RDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD DFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWAL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD VAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD VPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD VGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD VIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD LFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD EDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLME
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD RGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD SACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD VSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD QSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310
pF1KSD RTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ----------GT
:::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_005 RTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQPHRLWTLAEQGT
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KSD SGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSH
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KSD LGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDAN
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KSD GERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDG
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KSD SEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPI
1510 1520 1530 1540 1550 1560
pF1KSD YVAYNM
::::::
XP_005 YVAYNM
>>XP_011517732 (OMIM: 611380) PREDICTED: disco-interacti (1570 aa)
initn: 8624 init1: 8624 opt: 8624 Z-score: 7880.3 bits: 1470.9 E(85289): 0
Smith-Waterman score: 10234; 99.3% identity (99.3% similar) in 1538 aa overlap (29-1556:33-1570)
10 20 30 40 50
pF1KSD MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVDQAL
::::::::::::::::::::::::::::::
XP_011 CGVLWWTRATGRGVARWRRGAGRSVLWWMRGDITQKGYEKKRSKLIGAYLPQPPRVDQAL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD PQERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQERRAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD LVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD SSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTQSGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD AELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD GAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD SMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD RKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD PPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVN
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD VLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHW
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD ALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEAL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD TVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKP
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD DGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLL
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD GFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD RIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSET
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD KQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLG
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD QIEDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIEDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVML
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KSD MERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEV
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KSD SRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLD
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KSD FSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KSD GHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLS
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300
pF1KSD RVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ----------
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQPHRLWTLAEQ
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KSD GTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGD
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400 1410 1420
pF1KSD SHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTD
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KSD ANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVEL
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KSD DGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLD
1510 1520 1530 1540 1550 1560
1550
pF1KSD PIYVAYNM
::::::::
XP_011 PIYVAYNM
1570
>>XP_005252485 (OMIM: 611380) PREDICTED: disco-interacti (1622 aa)
initn: 8453 init1: 8453 opt: 8453 Z-score: 7723.8 bits: 1442.0 E(85289): 0
Smith-Waterman score: 10126; 95.8% identity (95.8% similar) in 1598 aa overlap (25-1556:25-1622)
10 20 30 40 50
pF1KSD MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPR-------
::::::::::::::::::::::::::::
XP_005 MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPTANGAAVV
10 20 30 40 50 60
60
pF1KSD -------------------------------------------------VDQALPQERRA
:::::::::::
XP_005 RCRLQHSEGAPRRTFRSAHIGVCDVREAAARERVASTAGNRPLFYFRFGVDQALPQERRA
70 80 90 100 110 120
70 80 90 100 110 120
pF1KSD PVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTS
130 140 150 160 170 180
130 140 150 160 170 180
pF1KSD MDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSG
190 200 210 220 230 240
190 200 210 220 230 240
pF1KSD GSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMET
250 260 270 280 290 300
250 260 270 280 290 300
pF1KSD GDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLA
310 320 330 340 350 360
310 320 330 340 350 360
pF1KSD MRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAY
370 380 390 400 410 420
370 380 390 400 410 420
pF1KSD SILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDAGS
430 440 450 460 470 480
430 440 450 460 470 480
pF1KSD QQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWF
490 500 510 520 530 540
490 500 510 520 530 540
pF1KSD PHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDFKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDFKK
550 560 570 580 590 600
550 560 570 580 590 600
pF1KSD DVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHR
610 620 630 640 650 660
610 620 630 640 650 660
pF1KSD DQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRR
670 680 690 700 710 720
670 680 690 700 710 720
pF1KSD PTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVPQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVPQL
730 740 750 760 770 780
730 740 750 760 770 780
pF1KSD CRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVGPG
790 800 810 820 830 840
790 800 810 820 830 840
pF1KSD GLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVIVA
850 860 870 880 890 900
850 860 870 880 890 900
pF1KSD EQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLE
910 920 930 940 950 960
910 920 930 940 950 960
pF1KSD GSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDND
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KSD QARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERGHL
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KSD QDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACL
1090 1100 1110 1120 1130 1140
1090 1100 1110 1120 1130 1140
pF1KSD MTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVSTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVSTT
1150 1160 1170 1180 1190 1200
1150 1160 1170 1180 1190 1200
pF1KSD GMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSIL
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KSD IPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCV
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310
pF1KSD VVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ----------GTSGPD
:::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_005 VVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQPHRLWTLAEQGTSGPD
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KSD PTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEI
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KSD WVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERH
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480 1490
pF1KSD DALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQE
1510 1520 1530 1540 1550 1560
1500 1510 1520 1530 1540 1550
pF1KSD ALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAY
1570 1580 1590 1600 1610 1620
pF1KSD NM
::
XP_005 NM
>>XP_011517730 (OMIM: 611380) PREDICTED: disco-interacti (1626 aa)
initn: 8453 init1: 8453 opt: 8453 Z-score: 7723.8 bits: 1442.0 E(85289): 0
Smith-Waterman score: 10104; 95.8% identity (95.8% similar) in 1594 aa overlap (29-1556:33-1626)
10 20 30 40 50
pF1KSD MADRSLEGMALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPR-----
::::::::::::::::::::::::
XP_011 CGVLWWTRATGRGVARWRRGAGRSVLWWMRGDITQKGYEKKRSKLIGAYLPQPPTANGAA
10 20 30 40 50 60
60
pF1KSD ---------------------------------------------------VDQALPQER
:::::::::
XP_011 VVRCRLQHSEGAPRRTFRSAHIGVCDVREAAARERVASTAGNRPLFYFRFGVDQALPQER
70 80 90 100 110 120
70 80 90 100 110 120
pF1KSD RAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAPVTPSSASRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQ
130 140 150 160 170 180
130 140 150 160 170 180
pF1KSD TSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQ
190 200 210 220 230 240
190 200 210 220 230 240
pF1KSD SGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGGSGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELM
250 260 270 280 290 300
250 260 270 280 290 300
pF1KSD ETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQM
310 320 330 340 350 360
310 320 330 340 350 360
pF1KSD LAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKV
370 380 390 400 410 420
370 380 390 400 410 420
pF1KSD AYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDA
430 440 450 460 470 480
430 440 450 460 470 480
pF1KSD GSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRD
490 500 510 520 530 540
490 500 510 520 530 540
pF1KSD WFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDF
550 560 570 580 590 600
550 560 570 580 590 600
pF1KSD KKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVA
610 620 630 640 650 660
610 620 630 640 650 660
pF1KSD HRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAI
670 680 690 700 710 720
670 680 690 700 710 720
pF1KSD RRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVP
730 740 750 760 770 780
730 740 750 760 770 780
pF1KSD QLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVG
790 800 810 820 830 840
790 800 810 820 830 840
pF1KSD PGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVI
850 860 870 880 890 900
850 860 870 880 890 900
pF1KSD VAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLF
910 920 930 940 950 960
910 920 930 940 950 960
pF1KSD LEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIED
970 980 990 1000 1010 1020
970 980 990 1000 1010 1020
pF1KSD NDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERG
1030 1040 1050 1060 1070 1080
1030 1040 1050 1060 1070 1080
pF1KSD HLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSA
1090 1100 1110 1120 1130 1140
1090 1100 1110 1120 1130 1140
pF1KSD CLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVS
1150 1160 1170 1180 1190 1200
1150 1160 1170 1180 1190 1200
pF1KSD TTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQS
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KSD ILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRT
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310
pF1KSD CVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ----------GTSG
:::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_011 CVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQPHRLWTLAEQGTSG
1330 1340 1350 1360 1370 1380
1320 1330 1340 1350 1360 1370
pF1KSD PDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLG
1390 1400 1410 1420 1430 1440
1380 1390 1400 1410 1420 1430
pF1KSD EIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGE
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480 1490
pF1KSD RHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSE
1510 1520 1530 1540 1550 1560
1500 1510 1520 1530 1540 1550
pF1KSD QEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYV
1570 1580 1590 1600 1610 1620
pF1KSD AYNM
::::
XP_011 AYNM
>>XP_011517734 (OMIM: 611380) PREDICTED: disco-interacti (1459 aa)
initn: 8102 init1: 8102 opt: 8102 Z-score: 7403.8 bits: 1382.6 E(85289): 0
Smith-Waterman score: 9712; 99.3% identity (99.3% similar) in 1459 aa overlap (108-1556:1-1459)
80 90 100 110 120 130
pF1KSD RSSGSRDERYRSDVHTEAVQAALAKHKERKMAVPMPSKRRSLVVQTSMDAYTPPDTSSGS
::::::::::::::::::::::::::::::
XP_011 MAVPMPSKRRSLVVQTSMDAYTPPDTSSGS
10 20 30
140 150 160 170 180 190
pF1KSD EDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDEGSVQGDSQGTPTSSQGSINMEHWISQAIHGSTTSTTSSSSTQSGGSGAAHRLADVMA
40 50 60 70 80 90
200 210 220 230 240 250
pF1KSD QTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTHIENHSAPPDVTTYTSEHSIQVERPQGSTGSRTAPKYGNAELMETGDGVPVSSRVSAK
100 110 120 130 140 150
260 270 280 290 300 310
pF1KSD IQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWP
160 170 180 190 200 210
320 330 340 350 360 370
pF1KSD PSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSLEAALQRWGTISPKAPCLTTMDTNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPM
220 230 240 250 260 270
380 390 400 410 420 430
pF1KSD VRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRPGDRVALVFPNNDPAAFMAAFYGCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVT
280 290 300 310 320 330
440 450 460 470 480 490
pF1KSD VALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VALTSDACHKGLPKSPTGEIPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYI
340 350 360 370 380 390
500 510 520 530 540 550
pF1KSD EYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYKTCKDGSVLGVTVTRTALLTHCQALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVM
400 410 420 430 440 450
560 570 580 590 600 610
pF1KSD NMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMMHVISIPYSLMKVNPLSWIQKVCQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRML
460 470 480 490 500 510
620 630 640 650 660 670
pF1KSD IVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVADGANPWSISSCDAFLNVFQSKGLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGV
520 530 540 550 560 570
680 690 700 710 720 730
pF1KSD LSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSMHGLTYGVIRVDSEEKLSVLTVQDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCA
580 590 600 610 620 630
740 750 760 770 780 790
pF1KSD VATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VATGTSYYGLSGMTKNTFEVFPMTSSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLM
640 650 660 670 680 690
800 810 820 830 840 850
pF1KSD VVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQ
700 710 720 730 740 750
860 870 880 890 900 910
pF1KSD WMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPH
760 770 780 790 800 810
920 930 940 950 960 970
pF1KSD TCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQ
820 830 840 850 860 870
980 990 1000 1010 1020 1030
pF1KSD WRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPG
880 890 900 910 920 930
1040 1050 1060 1070 1080 1090
pF1KSD IDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSR
940 950 960 970 980 990
1100 1110 1120 1130 1140 1150
pF1KSD EAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVSTTGMLAGVKMSHAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYLDFSVSTTGMLAGVKMSHAAT
1000 1010 1020 1030 1040 1050
1160 1170 1180 1190 1200 1210
pF1KSD SAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALW
1060 1070 1080 1090 1100 1110
1220 1230 1240 1250 1260 1270
pF1KSD LLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQ
1120 1130 1140 1150 1160 1170
1280 1290 1300 1310 1320
pF1KSD SFSKLFKDLGLHPRAVSTSFGCRVNLAICLQ----------GTSGPDPTTVYVDMRALRH
::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_011 SFSKLFKDLGLHPRAVSTSFGCRVNLAICLQPHRLWTLAEQGTSGPDPTTVYVDMRALRH
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KSD DRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNASGYFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRVRLVERGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNASGYFT
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420 1430 1440
pF1KSD IYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTELTDANGERHDALYVVGALDEAM
1300 1310 1320 1330 1340 1350
1450 1460 1470 1480 1490 1500
pF1KSD ELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVPLVTNVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGSEQEALDLVPLVTNVVL
1360 1370 1380 1390 1400 1410
1510 1520 1530 1540 1550
pF1KSD EEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIYVAYNM
1420 1430 1440 1450
>>XP_016875190 (OMIM: 136630,611379) PREDICTED: disco-in (1570 aa)
initn: 6712 init1: 5272 opt: 7811 Z-score: 7137.4 bits: 1333.4 E(85289): 0
Smith-Waterman score: 7820; 72.5% identity (89.7% similar) in 1576 aa overlap (1-1556:1-1570)
10 20 30 40 50
pF1KSD MADRSLEG-----MALPLEVRARLAELELELSEGDITQKGYEKKRSKLIGAYLPQPPRVD
::.:.:: ::: ::::.:::::::::::::::::::::::::.. : :: ..:
XP_016 MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD
10 20 30 40 50 60
60 70 80 90 100
pF1KSD QALPQERRAPV-TPSSA-----SRYHRRRSSGSRDERYRSDVHTEAVQAALAKHKERKMA
.:. .: : . .::.: :.::: ::.:.::::::::.::::::::::::::.:::
XP_016 SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD VPMPSKRRSLVVQTSMDAYTPPDTSSGSEDEGSVQGDSQGTPTSSQGSINMEHWISQAIH
.:::.:::: ::. :: :::::::.::::::.. .. . . .:. : : ::...:.
XP_016 LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD GSTTSTTSSSSTQSGG-SGAAHRLADVMAQTHIENHSAPPDVTTYTSEHSIQVE-RPQG-
::.::...::. . : .:.. ::::.:.:.::: :::::::: :: : . :: .
XP_016 GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANI
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD ---STGSRTAPKYGN--AELMETGDGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDF
.: . . :. . ::.:.::::::::::.:::::.:::::::::::.::::::
XP_016 DLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD EELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMD
::..:: ::::::::::: :: ..:: :::. ::::.::.::::::: . : :::..:
XP_016 EEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KSD TNGKPLYILTYGKLWTRSMKVAYSILHKLGTKQEPMVRPGDRVALVFPNNDPAAFMAAFY
.:::.: :::::::.::.:.::..:.:::::.::...::::::::.:::::. ::.:::
XP_016 MTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFY
370 380 390 400 410 420
410 420 430 440 450 460
pF1KSD GCLLAEVVPVPIEVPLTRKDAGSQQIGFLLGSCGVTVALTSDACHKGLPKSPTGEIPQFK
:::::::.::::: :::.:::::::::::...::::..: :::::. .::: :::
XP_016 GCLLAEVIPVPIE------DAGGQQIGFLLGSCGIALALTSEVCLKGLPKTQNGEIVQFK
430 440 450 460 470
470 480 490 500 510 520
pF1KSD GWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRTALLTHC
:::.: : ::.::.:::::.:: :::. :... ::::::: :.:::.::::.: :.:.::
XP_016 GWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHC
480 490 500 510 520 530
530 540 550 560 570 580
pF1KSD QALTQACGYTEAETIVNVLDFKKDVGLWHGILTSVMNMMHVISIPYSLMKVNPLSWIQKV
:::.:::.:.:.::::::::::::.:::::....::: ::.::.:::.::. ::::.:.:
XP_016 QALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRV
540 550 560 570 580 590
590 600 610 620 630 640
pF1KSD CQYKAKVACVKSRDMHWALVAHRDQRDINLSSLRMLIVADGANPWSISSCDAFLNVFQSK
.::::: :: ::.:::..:::::::..:::::::::.:::::::.:::::::..:::.
XP_016 HAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSH
600 610 620 630 640 650
650 660 670 680 690 700
pF1KSD GLRQEVICPCASSPEALTVAIRRPTDDSNQPPGRGVLSMHGLTYGVIRVDSEEKLSVLTV
::. :.:::::.: ::.::::::: . :::..:::.::.::::::..:.: :.:::
XP_016 GLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSALTV
660 670 680 690 700 710
710 720 730 740 750 760
pF1KSD QDVGLVMPGAIMCSVKPDGVPQLCRTDEIGELCVCAVATGTSYYGLSGMTKNTFEVFPMT
:::: ::::..:: ::::: ::::.::::::.:: . . : :.::.:.:::::::.:..
XP_016 QDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVN
720 730 740 750 760 770
770 780 790 800 810 820
pF1KSD SSGAPISEYPFIRTGLLGFVGPGGLVFVVGKMDGLMVVSGRRHNADDIVATALAVEPMKF
:.:.:... ::::.:::::::::.:::::::::::..::::::::::::::.:::: .:
XP_016 SAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKT
780 790 800 810 820 830
830 840 850 860 870 880
pF1KSD VYRGRIAVFSVTVLHDERIVIVAEQRPDSTEEDSFQWMSRVLQAIDSIHQVGVYCLALVP
:::::::::::.:..:::::.:::::::..::::::::::::::::::::::::::::::
XP_016 VYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP
840 850 860 870 880 890
890 900 910 920 930 940
pF1KSD ANTLPKTPLGGIHLSETKQLFLEGSLHPCNVLMCPHTCVTNLPKPRQKQPEIGPASVMVG
:::::::::::::.:.::::::::::::::.::::::::::::::::::: .::::::::
XP_016 ANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASVMVG
900 910 920 930 940 950
950 960 970 980 990 1000
pF1KSD NLVSGKRIAQASGRDLGQIEDNDQARKFLFLSEVLQWRAQTTPDHILYTLLNCRGAIANS
:::.:::::::.::::::::.:: .:: ::.:.::::::.::::.:. ::: .:. . .
XP_016 NLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLFMLLNAKGTTVCT
960 970 980 990 1000 1010
1010 1020 1030 1040 1050 1060
pF1KSD LTCVQLHKRAEKIAVMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPH
.:.:::::::.:: .: ..:::. ::.:.:.:::::.:::::::::::::.:.::::::
XP_016 ASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPH
1020 1030 1040 1050 1060 1070
1070 1080 1090 1100 1110 1120
pF1KSD PQNIATTLPTVKMIVEVSRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKR
::...:::::.:::.::..::..:.: . .:::::::::::::.::: :.::::::.::
XP_016 AQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTWPTIIDTDDLPRKR
1080 1090 1100 1110 1120 1130
1130 1140 1150 1160 1170 1180
pF1KSD PAQICKPCNPDTLAYLDFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLD
:. :: .:. ::::::::::::::.::::::.:..:.::.:::::::: ::..:::::
XP_016 LPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQIAICLD
1140 1150 1160 1170 1180 1190
1190 1200 1210 1220 1230 1240
pF1KSD PYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTK
:::::::.:::::::::::::.:::: :::.: ::: .:.:::.:::::::::::::::
XP_016 PYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSVMELCTK
1200 1210 1220 1230 1240 1250
1250 1260 1270 1280 1290 1300
pF1KSD GLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRV
:::.:.: ::.::..:: :::::::::::::.:: :::::::::.:: ::::::.:: ::
XP_016 GLGNQVEVLKTRGINLSCVRTCVVVAEERPRVALQQSFSKLFKDIGLSPRAVSTTFGSRV
1260 1270 1280 1290 1300 1310
1310 1320 1330 1340 1350 1360
pF1KSD NLAICLQGTSGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPE
:.::::::::::::::::::...::::::::::::.:.:: : :::::::::...:.:::
XP_016 NVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKVVIVNPE
1320 1330 1340 1350 1360 1370
1370 1380 1390 1400 1410 1420
pF1KSD TKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDT-QTIWARTGYLGF
::::.::::::::::.: :.::::.::: .:.::.::::.::::::. ::.:::::::::
XP_016 TKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWARTGYLGF
1380 1390 1400 1410 1420 1430
1430 1440 1450 1460 1470 1480
pF1KSD LRRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTN
.:::::: :.:::::::::::::::..::::.::::::::::: : :.:..:::::::::
XP_016 VRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECAVFTWTN
1440 1450 1460 1470 1480 1490
1490 1500 1510 1520 1530 1540
pF1KSD LLVVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRD
:::::::: :::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_016 LLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQRMHLRD
1500 1510 1520 1530 1540 1550
1550
pF1KSD GFLADQLDPIYVAYNM
.:::::::::::::::
XP_016 SFLADQLDPIYVAYNM
1560 1570
1556 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 04:17:08 2016 done: Thu Nov 3 04:17:10 2016
Total Scan time: 16.770 Total Display time: 0.930
Function used was FASTA [36.3.4 Apr, 2011]