Result of FASTA (omim) for
pF1KSDA0881
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0881, 1049 aa
1>>>pF1KSDA0881 1049 - 1049 aa - 1049 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.5303+/-0.000528; mu= -14.0946+/- 0.033
mean_var=906.3077+/-187.638, 0's: 0 Z-trim(124.1): 1071 B-trim: 0 in 0/58
Lambda= 0.042603
statistics sampled from 43711 (45242) to 43711 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.53), width: 16
Scan time: 14.270
The best scores are: opt bits E(85289)
NP_004774 (OMIM: 613199) serine/threonine-protein (1049) 6921 441.9 9.1e-123
XP_011544287 (OMIM: 613199) PREDICTED: serine/thre (1055) 6899 440.5 2.3e-122
XP_011544286 (OMIM: 613199) PREDICTED: serine/thre (1056) 6897 440.4 2.6e-122
XP_011544288 (OMIM: 613199) PREDICTED: serine/thre ( 851) 5312 342.8 4.7e-93
NP_001238972 (OMIM: 613199) serine/threonine-prote (1122) 4901 317.7 2.3e-85
NP_057235 (OMIM: 613199) serine/threonine-protein (1235) 4901 317.8 2.4e-85
XP_011544285 (OMIM: 613199) PREDICTED: serine/thre (1241) 4879 316.4 6.1e-85
XP_011544284 (OMIM: 613199) PREDICTED: serine/thre (1242) 4877 316.3 6.7e-85
XP_011523362 (OMIM: 610266) PREDICTED: serine/thre (1001) 2466 168.0 2.4e-40
NP_065842 (OMIM: 610266) serine/threonine-protein (1001) 2466 168.0 2.4e-40
NP_079418 (OMIM: 610266) serine/threonine-protein ( 853) 2275 156.2 7.3e-37
NP_001333419 (OMIM: 616711) serine/threonine-prote ( 737) 2037 141.5 1.7e-32
XP_016874901 (OMIM: 616711) PREDICTED: serine/thre ( 737) 2037 141.5 1.7e-32
XP_016874897 (OMIM: 616711) PREDICTED: serine/thre ( 907) 2037 141.6 1.9e-32
XP_016874898 (OMIM: 616711) PREDICTED: serine/thre ( 907) 2037 141.6 1.9e-32
XP_006719508 (OMIM: 616711) PREDICTED: serine/thre ( 907) 2037 141.6 1.9e-32
XP_005253955 (OMIM: 616711) PREDICTED: serine/thre ( 907) 2037 141.6 1.9e-32
XP_011536739 (OMIM: 616711) PREDICTED: serine/thre ( 907) 2037 141.6 1.9e-32
XP_016874899 (OMIM: 616711) PREDICTED: serine/thre ( 907) 2037 141.6 1.9e-32
NP_001333416 (OMIM: 616711) serine/threonine-prote ( 907) 2037 141.6 1.9e-32
XP_016874902 (OMIM: 616711) PREDICTED: serine/thre ( 728) 1989 138.5 1.3e-31
NP_001333421 (OMIM: 616711) serine/threonine-prote ( 728) 1989 138.5 1.3e-31
NP_001333420 (OMIM: 616711) serine/threonine-prote ( 728) 1989 138.5 1.3e-31
NP_001333418 (OMIM: 616711) serine/threonine-prote ( 898) 1989 138.6 1.5e-31
NP_001333417 (OMIM: 616711) serine/threonine-prote ( 898) 1989 138.6 1.5e-31
NP_057365 (OMIM: 616711) serine/threonine-protein ( 898) 1989 138.6 1.5e-31
NP_001333422 (OMIM: 616711) serine/threonine-prote ( 711) 1884 132.1 1.1e-29
NP_001333424 (OMIM: 616711) serine/threonine-prote ( 438) 1822 128.0 1.2e-28
NP_001333423 (OMIM: 616711) serine/threonine-prote ( 438) 1822 128.0 1.2e-28
NP_001333425 (OMIM: 616711) serine/threonine-prote ( 421) 1717 121.5 1e-26
NP_001333426 (OMIM: 616711) serine/threonine-prote ( 421) 1717 121.5 1e-26
NP_003567 (OMIM: 604984) serine/threonine-protein ( 443) 781 64.0 2.1e-09
NP_001027467 (OMIM: 604984) serine/threonine-prote ( 431) 780 63.9 2.2e-09
XP_016876284 (OMIM: 604984) PREDICTED: serine/thre ( 474) 781 64.0 2.2e-09
XP_016876283 (OMIM: 604984) PREDICTED: serine/thre ( 517) 780 64.0 2.5e-09
XP_005260588 (OMIM: 604965,614868) PREDICTED: seri ( 478) 774 63.6 3e-09
XP_005260587 (OMIM: 604965,614868) PREDICTED: seri ( 503) 774 63.6 3.1e-09
XP_016869247 (OMIM: 605030) PREDICTED: serine/thre ( 456) 771 63.4 3.3e-09
NP_006272 (OMIM: 605030) serine/threonine-protein ( 491) 771 63.4 3.5e-09
NP_001243241 (OMIM: 605030) serine/threonine-prote ( 519) 771 63.5 3.6e-09
XP_011515553 (OMIM: 605030) PREDICTED: serine/thre ( 522) 771 63.5 3.6e-09
XP_016869246 (OMIM: 605030) PREDICTED: serine/thre ( 524) 771 63.5 3.7e-09
NP_001258907 (OMIM: 602255) serine/threonine-prote ( 426) 767 63.1 3.8e-09
NP_001258906 (OMIM: 602255) serine/threonine-prote ( 426) 767 63.1 3.8e-09
NP_006365 (OMIM: 602255) serine/threonine-protein ( 426) 767 63.1 3.8e-09
XP_011515550 (OMIM: 605030) PREDICTED: serine/thre ( 576) 771 63.5 3.9e-09
XP_016869245 (OMIM: 605030) PREDICTED: serine/thre ( 580) 771 63.5 3.9e-09
XP_005260590 (OMIM: 604965,614868) PREDICTED: seri ( 462) 767 63.2 4e-09
NP_006273 (OMIM: 604965,614868) serine/threonine-p ( 487) 767 63.2 4.1e-09
XP_011508795 (OMIM: 602255) PREDICTED: serine/thre ( 376) 763 62.8 4.2e-09
>>NP_004774 (OMIM: 613199) serine/threonine-protein kina (1049 aa)
initn: 6921 init1: 6921 opt: 6921 Z-score: 2325.0 bits: 441.9 E(85289): 9.1e-123
Smith-Waterman score: 6921; 100.0% identity (100.0% similar) in 1049 aa overlap (1-1049:1-1049)
10 20 30 40 50 60
pF1KSD MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEEAEPYMHRAGTLTSLESSHSVPSMSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEEAEPYMHRAGTLTSLESSHSVPSMSIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD ASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD GSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD KLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD NPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD NKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLLETTPKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLLETTPKAQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD HKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQLQQELELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQLQQELELL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD NAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIRSLLERQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIRSLLERQA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD REIEAFDAESMRLGFSSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHWSHGPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 REIEAFDAESMRLGFSSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHWSHGPPPP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD GMPPPAWRQPSLLAPPGPPNWLGPPTQSGTPRGGALLLLRNSPQPLRRAASGGSGSENVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GMPPPAWRQPSLLAPPGPPNWLGPPTQSGTPRGGALLLLRNSPQPLRRAASGGSGSENVG
970 980 990 1000 1010 1020
1030 1040
pF1KSD PPAAAVPGPLSRSTSVASHILNGSSHFYS
:::::::::::::::::::::::::::::
NP_004 PPAAAVPGPLSRSTSVASHILNGSSHFYS
1030 1040
>>XP_011544287 (OMIM: 613199) PREDICTED: serine/threonin (1055 aa)
initn: 4676 init1: 4676 opt: 6899 Z-score: 2317.7 bits: 440.5 E(85289): 2.3e-122
Smith-Waterman score: 6899; 99.4% identity (99.4% similar) in 1055 aa overlap (1-1049:1-1055)
10 20 30 40 50 60
pF1KSD MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
250 260 270 280 290 300
310 320 330 340 350
pF1KSD VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEE------EAEPYMHRAGTLTSLESSHSV
::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEPTPCSQEAEPYMHRAGTLTSLESSHSV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD PSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD IIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD VSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAG
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD FGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD KEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLAR
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD HSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTEL
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD GNQLEYNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNQLEYNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLLE
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD TTPKAQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTPKAQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQLQ
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD QELELLNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QELELLNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIRS
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD LLERQAREIEAFDAESMRLGFSSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLERQAREIEAFDAESMRLGFSSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHWS
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD HGPPPPGMPPPAWRQPSLLAPPGPPNWLGPPTQSGTPRGGALLLLRNSPQPLRRAASGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGPPPPGMPPPAWRQPSLLAPPGPPNWLGPPTQSGTPRGGALLLLRNSPQPLRRAASGGS
970 980 990 1000 1010 1020
1020 1030 1040
pF1KSD GSENVGPPAAAVPGPLSRSTSVASHILNGSSHFYS
:::::::::::::::::::::::::::::::::::
XP_011 GSENVGPPAAAVPGPLSRSTSVASHILNGSSHFYS
1030 1040 1050
>>XP_011544286 (OMIM: 613199) PREDICTED: serine/threonin (1056 aa)
initn: 4676 init1: 4676 opt: 6897 Z-score: 2317.0 bits: 440.4 E(85289): 2.6e-122
Smith-Waterman score: 6897; 99.3% identity (99.3% similar) in 1056 aa overlap (1-1049:1-1056)
10 20 30 40 50 60
pF1KSD MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
250 260 270 280 290 300
310 320 330 340 350
pF1KSD VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEE-------EAEPYMHRAGTLTSLESSHS
::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_011 VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEQPTPCSQEAEPYMHRAGTLTSLESSHS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD VPSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD SIIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTAS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD LVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD GFGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQ
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD LKEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLA
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD RHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD LGNQLEYNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGNQLEYNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLL
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD ETTPKAQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETTPKAQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQL
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD QQELELLNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQELELLNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIR
850 860 870 880 890 900
900 910 920 930 940 950
pF1KSD SLLERQAREIEAFDAESMRLGFSSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLERQAREIEAFDAESMRLGFSSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHW
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KSD SHGPPPPGMPPPAWRQPSLLAPPGPPNWLGPPTQSGTPRGGALLLLRNSPQPLRRAASGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHGPPPPGMPPPAWRQPSLLAPPGPPNWLGPPTQSGTPRGGALLLLRNSPQPLRRAASGG
970 980 990 1000 1010 1020
1020 1030 1040
pF1KSD SGSENVGPPAAAVPGPLSRSTSVASHILNGSSHFYS
::::::::::::::::::::::::::::::::::::
XP_011 SGSENVGPPAAAVPGPLSRSTSVASHILNGSSHFYS
1030 1040 1050
>>XP_011544288 (OMIM: 613199) PREDICTED: serine/threonin (851 aa)
initn: 5391 init1: 3089 opt: 5312 Z-score: 1791.6 bits: 342.8 E(85289): 4.7e-93
Smith-Waterman score: 5312; 99.0% identity (99.1% similar) in 823 aa overlap (1-816:1-823)
10 20 30 40 50 60
pF1KSD MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
250 260 270 280 290 300
310 320 330 340 350
pF1KSD VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEE-------EAEPYMHRAGTLTSLESSHS
::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_011 VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEQPTPCSQEAEPYMHRAGTLTSLESSHS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD VPSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD SIIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTAS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD LVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD GFGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQ
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD LKEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLA
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD RHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD LGNQLEYNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGNQLEYNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLL
730 740 750 760 770 780
780 790 800 810 820 830
pF1KSD ETTPKAQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQL
::::::::::::::::::::::::::::::::::::::::::.
XP_011 ETTPKAQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQAVVSSILLSQRFREHLEHM
790 800 810 820 830 840
840 850 860 870 880 890
pF1KSD QQELELLNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIR
XP_011 CKYTWGIDSAV
850
>>NP_001238972 (OMIM: 613199) serine/threonine-protein k (1122 aa)
initn: 4948 init1: 4901 opt: 4901 Z-score: 1653.7 bits: 317.7 E(85289): 2.3e-85
Smith-Waterman score: 4901; 99.5% identity (99.7% similar) in 748 aa overlap (1-748:1-748)
10 20 30 40 50 60
pF1KSD MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEEAEPYMHRAGTLTSLESSHSVPSMSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEEAEPYMHRAGTLTSLESSHSVPSMSIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD ASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD GSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD KLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD NPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD NKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLLETTPKAQ
:::::::::::::::::::::::: . .
NP_001 NKRREQELRQKHAAQVRQQPKSLKERSIVGQEEAGTWSLWGKEDESLLDEEFELGWVQGP
730 740 750 760 770 780
>>NP_057235 (OMIM: 613199) serine/threonine-protein kina (1235 aa)
initn: 4948 init1: 4901 opt: 4901 Z-score: 1653.2 bits: 317.8 E(85289): 2.4e-85
Smith-Waterman score: 4903; 78.7% identity (84.7% similar) in 1019 aa overlap (1-1015:1-984)
10 20 30 40 50 60
pF1KSD MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEEAEPYMHRAGTLTSLESSHSVPSMSIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEEAEPYMHRAGTLTSLESSHSVPSMSIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD ASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD GSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQIQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD EHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEAE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD KLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD NPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD LLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEY
670 680 690 700 710 720
730 740 750 760 770
pF1KSD NKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLLETTP--K
:::::::::::::::::::::::: . : . : . .: :
NP_057 NKRREQELRQKHAAQVRQQPKSLKVRAGQ--RPPGLPLPIPGALGPPNTGTPIEQQPCSP
730 740 750 760 770
780 790 800 810 820 830
pF1KSD AQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQLQQELE
.:. : .:. :.:. .....: :. . : .. .:.. :
NP_057 GQEAVLDQRM----------LGEE-EEAVGER------RILGKEGATLEPKQQRILGE--
780 790 800 810
840 850 860 870 880 890
pF1KSD LLNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIRSLLER
.: . ..: . :. .: . . : :: . .. ... .
NP_057 -----ESGAPSPSPQKHGSLVD--EEVWGLPEEIEELRVPSLVPQERSIVGQEEAGTWSL
820 830 840 850 860 870
900 910 920 930 940 950
pF1KSD QAREIEAFDAESMRLGF-SSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHWSHGP
..: :.. : ..::. .. :: .: : . :: .: :. : :
NP_057 WGKEDESLLDEEFELGWVQGPALTPVPEEEEEEEEGAPIGTPRDPGDGCPSPDI--PPEP
880 890 900 910 920 930
960 970 980 990 1000 1010
pF1KSD PPPGMPP-PAWRQPSLLAPPGPPNWLGPPTQSGTPRGGALLLLRNSPQPLRRAASGGSGS
:: . : :: . :.::. : :. . :.. :::: :: ::.::.:
NP_057 PPTHLRPCPASQLPGLLSH-GLLAGLSFAVGSSSGLLPLLLLLL---LPLL-AAQGGGGL
940 950 960 970 980
1020 1030 1040
pF1KSD ENVGPPAAAVPGPLSRSTSVASHILNGSSHFYS
NP_057 QAALLALEVGLVGLGASYLLLCTALHLPSSLFLLLAQGTALGAVLGLSWRRGLMGVPLGL
990 1000 1010 1020 1030 1040
>>XP_011544285 (OMIM: 613199) PREDICTED: serine/threonin (1241 aa)
initn: 2656 init1: 2656 opt: 4879 Z-score: 1645.9 bits: 316.4 E(85289): 6.1e-85
Smith-Waterman score: 4881; 78.2% identity (84.2% similar) in 1025 aa overlap (1-1015:1-990)
10 20 30 40 50 60
pF1KSD MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
250 260 270 280 290 300
310 320 330 340 350
pF1KSD VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEE------EAEPYMHRAGTLTSLESSHSV
::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEPTPCSQEAEPYMHRAGTLTSLESSHSV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD PSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD IIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD VSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAG
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD FGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD KEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLAR
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD HSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTEL
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD GNQLEYNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLLE
:::::::::::::::::::::::::::::: . : . : . .:
XP_011 GNQLEYNKRREQELRQKHAAQVRQQPKSLKVRAGQ--RPPGLPLPIPGALGPPNTGTPIE
730 740 750 760 770
780 790 800 810 820 830
pF1KSD TTP--KAQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQ
: .:. : .:. :.:. .....: :. . : .. .:.
XP_011 QQPCSPGQEAVLDQRM----------LGEE-EEAVGER------RILGKEGATLEPKQQR
780 790 800 810 820
840 850 860 870 880 890
pF1KSD LQQELELLNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERI
. : .: . ..: . :. .: . . : :: . .. ...
XP_011 ILGE-------ESGAPSPSPQKHGSLVD--EEVWGLPEEIEELRVPSLVPQERSIVGQEE
830 840 850 860 870
900 910 920 930 940 950
pF1KSD RSLLERQAREIEAFDAESMRLGF-SSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGA
. ..: :.. : ..::. .. :: .: : . :: .: :. :
XP_011 AGTWSLWGKEDESLLDEEFELGWVQGPALTPVPEEEEEEEEGAPIGTPRDPGDGCPSPDI
880 890 900 910 920 930
960 970 980 990 1000 1010
pF1KSD HWSHGPPPPGMPP-PAWRQPSLLAPPGPPNWLGPPTQSGTPRGGALLLLRNSPQPLRRAA
::: . : :: . :.::. : :. . :.. :::: :: ::
XP_011 --PPEPPPTHLRPCPASQLPGLLSH-GLLAGLSFAVGSSSGLLPLLLLLL---LPLL-AA
940 950 960 970 980
1020 1030 1040
pF1KSD SGGSGSENVGPPAAAVPGPLSRSTSVASHILNGSSHFYS
.::.:
XP_011 QGGGGLQAALLALEVGLVGLGASYLLLCTALHLPSSLFLLLAQGTALGAVLGLSWRRGLM
990 1000 1010 1020 1030 1040
>>XP_011544284 (OMIM: 613199) PREDICTED: serine/threonin (1242 aa)
initn: 2656 init1: 2656 opt: 4877 Z-score: 1645.2 bits: 316.3 E(85289): 6.7e-85
Smith-Waterman score: 4879; 78.2% identity (84.1% similar) in 1026 aa overlap (1-1015:1-991)
10 20 30 40 50 60
pF1KSD MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
250 260 270 280 290 300
310 320 330 340 350
pF1KSD VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEE-------EAEPYMHRAGTLTSLESSHS
::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_011 VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEQPTPCSQEAEPYMHRAGTLTSLESSHS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD VPSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPSMSISASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD SIIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIIHRLPGSDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTAS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD LVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD GFGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQ
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD LKEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLA
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD RHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KSD LGNQLEYNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLL
::::::::::::::::::::::::::::::: . : . : . .
XP_011 LGNQLEYNKRREQELRQKHAAQVRQQPKSLKVRAGQ--RPPGLPLPIPGALGPPNTGTPI
730 740 750 760 770
780 790 800 810 820 830
pF1KSD ETTP--KAQHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQ
: : .:. : .:. :.:. .....: :. . : .. .:
XP_011 EQQPCSPGQEAVLDQRM----------LGEE-EEAVGER------RILGKEGATLEPKQQ
780 790 800 810 820
840 850 860 870 880 890
pF1KSD QLQQELELLNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSER
.. : .: . ..: . :. .: . . : :: . .. ...
XP_011 RILGE-------ESGAPSPSPQKHGSLVD--EEVWGLPEEIEELRVPSLVPQERSIVGQE
830 840 850 860 870
900 910 920 930 940 950
pF1KSD IRSLLERQAREIEAFDAESMRLGF-SSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSG
. ..: :.. : ..::. .. :: .: : . :: .: :. :
XP_011 EAGTWSLWGKEDESLLDEEFELGWVQGPALTPVPEEEEEEEEGAPIGTPRDPGDGCPSPD
880 890 900 910 920 930
960 970 980 990 1000
pF1KSD AHWSHGPPPPGMPP-PAWRQPSLLAPPGPPNWLGPPTQSGTPRGGALLLLRNSPQPLRRA
::: . : :: . :.::. : :. . :.. :::: :: :
XP_011 I--PPEPPPTHLRPCPASQLPGLLSH-GLLAGLSFAVGSSSGLLPLLLLLL---LPLL-A
940 950 960 970 980
1010 1020 1030 1040
pF1KSD ASGGSGSENVGPPAAAVPGPLSRSTSVASHILNGSSHFYS
:.::.:
XP_011 AQGGGGLQAALLALEVGLVGLGASYLLLCTALHLPSSLFLLLAQGTALGAVLGLSWRRGL
990 1000 1010 1020 1030 1040
>>XP_011523362 (OMIM: 610266) PREDICTED: serine/threonin (1001 aa)
initn: 4577 init1: 2357 opt: 2466 Z-score: 845.4 bits: 168.0 E(85289): 2.4e-40
Smith-Waterman score: 4769; 70.4% identity (86.3% similar) in 1052 aa overlap (1-1049:1-1001)
10 20 30 40 50 60
pF1KSD MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
::. .::::::::..::::::.::::::.::::::::::::::::::::..:::::::::
XP_011 MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
::::::.::::::::::.:::...:::.:.:.::::::::::::::::::::::::::::
XP_011 YSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
::::::::::.::::::::::::::.:::::.:::::::.::: :::.::::::. .:::
XP_011 KPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
:::.:::..::.::::::::::::::::::::: :::: ::::::: ::..:::::::::
XP_011 ESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHIFVLRERPETVLIDLIQRTKDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEEAEPYMHRAGTLTSLESSHSVPSMSIS
::::::::::::::.::::: :::..:: ::::: . . :.::..:. :..:.::::::
XP_011 VRELDNLQYRKMKKLLFQEAHNGPAVEAQEEEEEQDHGVGRTGTVNSVGSNQSIPSMSIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD ASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLP
::::::::::: :.::.. : . :.::.::: :.::.:: :
XP_011 ASSQSSSVNSLPDVSDDKSELD-------------------MMEGDHTVMSNSSVIHLKP
370 380 390 400
430 440 450 460 470
pF1KSD GSDNLYDDPYQPEITPS-PLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQI
.: : . .:. : : .:: . .:.... :::.:::::::::::.::.
XP_011 EEEN-YREEGDPRTRASDPQSPPQV---------SRHKSHYRNREHFATIRTASLVTRQM
410 420 430 440 450
480 490 500 510 520 530
pF1KSD QEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEA
::::::: ::::.::::::::::::::..::..:..: .:: ::...::.:: .:.::
XP_011 QEHEQDSELREQMSGYKRMRRQHQKQLMTLENKLKAEMDEHRLRLDKDLETQRNNFAAEM
460 470 480 490 500 510
540 550 560 570 580 590
pF1KSD EKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQ
::: ..::: ::::.. . ::.:::::: .:::::: ..::.::: ::::::::::::.
XP_011 EKLIKKHQAAMEKEAKVMSNEEKKFQQHIQAQQKKELNSFLESQKREYKLRKEQLKEELN
520 530 540 550 560 570
600 610 620 630 640 650
pF1KSD ENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQ
:: ::::.:: ::: .:::..:. ::::::.::::::::.::.::..::.:::.::.:.:
XP_011 ENQSTPKKEKQEWLSKQKENIQHFQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQ
580 590 600 610 620 630
660 670 680 690 700 710
pF1KSD DLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLE
::.::.:::.::::::: :.::::::. .:::.:.:...:. : :: :::::::: ::::
XP_011 DLVREELNKRQTQKDLEHAMLLRQHESMQELEFRHLNTIQKMRCELIRLQHQTELTNQLE
640 650 660 670 680 690
720 730 740 750 760 770
pF1KSD YNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLLETTPKA
::::::.:::.::. .::::::::::::::::::::.::::::::::::: ::::::::.
XP_011 YNKRRERELRRKHVMEVRQQPKSLKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKS
700 710 720 730 740 750
780 790 800 810 820 830
pF1KSD QHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQLQQELEL
.::..::::::::::::::::::::.::.::::.:::::::.:::: :.:..::::::::
XP_011 EHKAVLKRLKEEQTRKLAILAEQYDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELEL
760 770 780 790 800 810
840 850 860 870 880 890
pF1KSD LNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIRSLLERQ
:::::::::...:.::.::::::::::.::::::::..:::.::::. :.::::::::::
XP_011 LNAYQSKIKMQAEAQHDRELRELEQRVSLRRALLEQKIEEEMLALQNERTERIRSLLERQ
820 830 840 850 860 870
900 910 920 930 940 950
pF1KSD AREIEAFDAESMRLGFSSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHWSHGPPP
::::::::.::::::::.:.:... :: ...::. : .: :. : ::.: :
XP_011 AREIEAFDSESMRLGFSNMVLSNLSPEAFSHSYPG---ASGWSHNPTGGPGPHWGH---P
880 890 900 910 920
960 970 980 990 1000 1010
pF1KSD PGMPPPAWRQPSLLAPPGPPNWLGP--PTQSGTPRGGALLLLRNSPQPLRRAASGGSGSE
: :: :: .: :: : : : : :.:::... . ::::: :::.:::: .
XP_011 MGGPPQAWGHP---MQGGPQPWGHPSGPMQ-GVPRGSSMGV-RNSPQALRRTASGGRTEQ
930 940 950 960 970 980
1020 1030 1040
pF1KSD NVGPPAAAVPGPLSRSTSVASHILNGSSHFYS
. .::::::.:.: ::: :.
XP_011 G-----------MSRSTSVTSQISNGSHMSYT
990 1000
>>NP_065842 (OMIM: 610266) serine/threonine-protein kina (1001 aa)
initn: 4577 init1: 2357 opt: 2466 Z-score: 845.4 bits: 168.0 E(85289): 2.4e-40
Smith-Waterman score: 4769; 70.4% identity (86.3% similar) in 1052 aa overlap (1-1049:1-1001)
10 20 30 40 50 60
pF1KSD MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMS
::. .::::::::..::::::.::::::.::::::::::::::::::::..:::::::::
NP_065 MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD YSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHK
::::::.::::::::::.:::...:::.:.:.::::::::::::::::::::::::::::
NP_065 YSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD KPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPAN
::::::::::.::::::::::::::.:::::.:::::::.::: :::.::::::. .:::
NP_065 KPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPAN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD ESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDA
:::.:::..::.::::::::::::::::::::: :::: ::::::: ::..:::::::::
NP_065 ESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHIFVLRERPETVLIDLIQRTKDA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD VRELDNLQYRKMKKILFQEAPNGPGAEAPEEEEEAEPYMHRAGTLTSLESSHSVPSMSIS
::::::::::::::.::::: :::..:: ::::: . . :.::..:. :..:.::::::
NP_065 VRELDNLQYRKMKKLLFQEAHNGPAVEAQEEEEEQDHGVGRTGTVNSVGSNQSIPSMSIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD ASSQSSSVNSLADASDNEEEEEEEEEEEEEEEGPEAREMAMMQEGEHTVTSHSSIIHRLP
::::::::::: :.::.. : . :.::.::: :.::.:: :
NP_065 ASSQSSSVNSLPDVSDDKSELD-------------------MMEGDHTVMSNSSVIHLKP
370 380 390 400
430 440 450 460 470
pF1KSD GSDNLYDDPYQPEITPS-PLQPPAAPAPTSTTSSARRRAYCRNRDHFATIRTASLVSRQI
.: : . .:. : : .:: . .:.... :::.:::::::::::.::.
NP_065 EEEN-YREEGDPRTRASDPQSPPQV---------SRHKSHYRNREHFATIRTASLVTRQM
410 420 430 440 450
480 490 500 510 520 530
pF1KSD QEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEA
::::::: ::::.::::::::::::::..::..:..: .:: ::...::.:: .:.::
NP_065 QEHEQDSELREQMSGYKRMRRQHQKQLMTLENKLKAEMDEHRLRLDKDLETQRNNFAAEM
460 470 480 490 500 510
540 550 560 570 580 590
pF1KSD EKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQ
::: ..::: ::::.. . ::.:::::: .:::::: ..::.::: ::::::::::::.
NP_065 EKLIKKHQAAMEKEAKVMSNEEKKFQQHIQAQQKKELNSFLESQKREYKLRKEQLKEELN
520 530 540 550 560 570
600 610 620 630 640 650
pF1KSD ENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQ
:: ::::.:: ::: .:::..:. ::::::.::::::::.::.::..::.:::.::.:.:
NP_065 ENQSTPKKEKQEWLSKQKENIQHFQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQ
580 590 600 610 620 630
660 670 680 690 700 710
pF1KSD DLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLE
::.::.:::.::::::: :.::::::. .:::.:.:...:. : :: :::::::: ::::
NP_065 DLVREELNKRQTQKDLEHAMLLRQHESMQELEFRHLNTIQKMRCELIRLQHQTELTNQLE
640 650 660 670 680 690
720 730 740 750 760 770
pF1KSD YNKRREQELRQKHAAQVRQQPKSLKSKELQIKKQFQETCKIQTRQYKALRAHLLETTPKA
::::::.:::.::. .::::::::::::::::::::.::::::::::::: ::::::::.
NP_065 YNKRRERELRRKHVMEVRQQPKSLKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKS
700 710 720 730 740 750
780 790 800 810 820 830
pF1KSD QHKSLLKRLKEEQTRKLAILAEQYDQSISEMLSSQALRLDETQEAEFQALRQQLQQELEL
.::..::::::::::::::::::::.::.::::.:::::::.:::: :.:..::::::::
NP_065 EHKAVLKRLKEEQTRKLAILAEQYDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELEL
760 770 780 790 800 810
840 850 860 870 880 890
pF1KSD LNAYQSKIKIRTESQHERELRELEQRVALRRALLEQRVEEELLALQTGRSERIRSLLERQ
:::::::::...:.::.::::::::::.::::::::..:::.::::. :.::::::::::
NP_065 LNAYQSKIKMQAEAQHDRELRELEQRVSLRRALLEQKIEEEMLALQNERTERIRSLLERQ
820 830 840 850 860 870
900 910 920 930 940 950
pF1KSD AREIEAFDAESMRLGFSSMALGGIPAEAAAQGYPAPPPAPAWPSRPVPRSGAHWSHGPPP
::::::::.::::::::.:.:... :: ...::. : .: :. : ::.: :
NP_065 AREIEAFDSESMRLGFSNMVLSNLSPEAFSHSYPG---ASGWSHNPTGGPGPHWGH---P
880 890 900 910 920
960 970 980 990 1000 1010
pF1KSD PGMPPPAWRQPSLLAPPGPPNWLGP--PTQSGTPRGGALLLLRNSPQPLRRAASGGSGSE
: :: :: .: :: : : : : :.:::... . ::::: :::.:::: .
NP_065 MGGPPQAWGHP---MQGGPQPWGHPSGPMQ-GVPRGSSMGV-RNSPQALRRTASGGRTEQ
930 940 950 960 970 980
1020 1030 1040
pF1KSD NVGPPAAAVPGPLSRSTSVASHILNGSSHFYS
. .::::::.:.: ::: :.
NP_065 G-----------MSRSTSVTSQISNGSHMSYT
990 1000
1049 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 03:54:59 2016 done: Thu Nov 3 03:55:01 2016
Total Scan time: 14.270 Total Display time: 0.400
Function used was FASTA [36.3.4 Apr, 2011]