Result of FASTA (omim) for
pF1KSDA0741
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0741, 1220 aa
1>>>pF1KSDA0741 1220 - 1220 aa - 1220 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.3520+/-0.000657; mu= -34.5962+/- 0.041
mean_var=832.4769+/-169.903, 0's: 0 Z-trim(120.3): 103 B-trim: 0 in 0/58
Lambda= 0.044452
statistics sampled from 35237 (35340) to 35237 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.414), width: 16
Scan time: 13.130
The best scores are: opt bits E(85289)
NP_056988 (OMIM: 606086) eukaryotic translation in (1220) 7810 517.8 1.7e-145
NP_001778 (OMIM: 176873) cyclin-dependent kinase 1 ( 795) 419 43.6 0.006
>>NP_056988 (OMIM: 606086) eukaryotic translation initia (1220 aa)
initn: 7810 init1: 7810 opt: 7810 Z-score: 2733.0 bits: 517.8 E(85289): 1.7e-145
Smith-Waterman score: 7810; 99.9% identity (99.9% similar) in 1220 aa overlap (1-1220:1-1220)
10 20 30 40 50 60
pF1KSD MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD ELEGLSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKD
::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERER
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD TPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD ATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD PEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD KEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTGKTKILDKLRHTHVQDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDTGKTKILDKLRHTHVQDGE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD AGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLIIDTPGHESFSNLRNRGSSLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLIIDTPGHESFSNLRNRGSSLC
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD DIAILVVDIMHGLEPQTIESINLLKSKKCPFIVALNKIDRLYDWKKSPDSDVAATLKKQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DIAILVVDIMHGLEPQTIESINLLKSKKCPFIVALNKIDRLYDWKKSPDSDVAATLKKQK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD KNTKDEFEERAKAIIVEFAQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KNTKDEFEERAKAIIVEFAQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD LTQTMLSKRLAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIVTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LTQTMLSKRLAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIVTQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD IRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPVLK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD DELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFLKTSEVPYAGINIGPVHKKDVMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFLKTSEVPYAGINIGPVHKKDVMK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD ASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFSAEIIYHLFDAFTKYRQDYKKQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFSAEIIYHLFDAFTKYRQDYKKQK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD QEEFKHIAVFPCKIKILPQYIFNSRDPIVMGVTVEAGQVKQGTPMCVPSKNFVDIGIVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QEEFKHIAVFPCKIKILPQYIFNSRDPIVMGVTVEAGQVKQGTPMCVPSKNFVDIGIVTS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD IEINHKQVDVAKKGQEVCVKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWFRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IEINHKQVDVAKKGQEVCVKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWFRD
1150 1160 1170 1180 1190 1200
1210 1220
pF1KSD EMQKSDWQLIVELKKVFEII
::::::::::::::::::::
NP_056 EMQKSDWQLIVELKKVFEII
1210 1220
>>NP_001778 (OMIM: 176873) cyclin-dependent kinase 11B i (795 aa)
initn: 731 init1: 275 opt: 419 Z-score: 173.9 bits: 43.6 E(85289): 0.006
Smith-Waterman score: 443; 26.5% identity (56.8% similar) in 565 aa overlap (215-752:2-535)
190 200 210 220 230 240
pF1KSD ESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRD
:.: : :.:.::. . ::: :.:..
NP_001 MGDEKD--SWKVKTLDEILQEKK---RRKEQ
10 20
250 260 270 280 290 300
pF1KSD EEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTA
::::....::.... .. :.:. .. : . . : :.... : .: . .
NP_001 EEKAEIKRLKNSDDRDS-KRDSLEEGELRDHRMEITIRNS--------PYRREDSMEDRG
30 40 50 60 70
310 320 330 340 350 360
pF1KSD AEDDNEGDKKKKD---KKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEE-ERQKR
:::. . : .. :.: . .:.::.:::.. :. .... ..: .: ::.: ::.::
NP_001 EEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSH-SAEGGKHARVKEKEREHERRKR
80 90 100 110 120 130
370 380 390 400 410
pF1KSD EEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERK---ERLKKEGKLLTKSQREARA
..::. : .: : ....: :. .::: . .. ::: :: .: . . :.: .
NP_001 HREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER
140 150 160 170 180 190
420 430 440 450 460 470
pF1KSD RAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVME
::: : .:. :: .. : : :: . . .. . : .:: . . :
NP_001 RAEERRKEREARR-EVSAHHR--TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPGE
200 210 220 230 240 250
480 490 500 510 520 530
pF1KSD QGVPEKEETPPPVEPE--EEED--TEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEE
. : . : .. : ::.: .. ..: : .:. :. ..:... : .:. ::
NP_001 -ARPAPAQKPAQLKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE
260 270 280 290 300 310
540 550 560 570 580
pF1KSD EEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSS----
:::: ::.:: ::::::: : ::...: .:. : :. : . ... .: .
NP_001 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ-SAEEVSEEEMSEDEERENENHLLV
320 330 340 350 360 370
590 600 610 620 630 640
pF1KSD --DSEYDSDDDRTKEER-----AYDKAKRRIEKRRLEHSKNVNTEKLRAPIICVLGHVDT
.:..: :. ...: . . ... : . : .. .:. . : ..
NP_001 VPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQ-
380 390 400 410 420 430
650 660 670 680 690 700
pF1KSD GKTKILDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLIID
: .. . .....: : . . . . :. .. :: : ..:. : .. :.
NP_001 GCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVAL-KRLKMEK--EKEGFPITSLREIN
440 450 460 470 480
710 720 730 740 750
pF1KSD T---PGHESFSNLRN--RGSSLCDIAILVVDIMHGLEPQTIESINLLKSKKCPFIVALNK
: : .. ..:. ::.. : :.. . : :. .:... : ::.
NP_001 TILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLK-------SLMETMKQPFLPGEVK
490 500 510 520 530 540
760 770 780 790 800 810
pF1KSD IDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIVEFAQQGLNAALFYENKDPRTF
NP_001 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT
550 560 570 580 590 600
1220 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 02:52:56 2016 done: Thu Nov 3 02:52:58 2016
Total Scan time: 13.130 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]