Result of FASTA (omim) for
pF1KSDA0712
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0712, 1738 aa
1>>>pF1KSDA0712 1738 - 1738 aa - 1738 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6198+/-0.00042; mu= -6.9132+/- 0.026
mean_var=295.7115+/-61.132, 0's: 0 Z-trim(119.9): 401 B-trim: 17 in 1/60
Lambda= 0.074583
statistics sampled from 33979 (34389) to 33979 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.403), width: 16
Scan time: 17.450
The best scores are: opt bits E(85289)
NP_055530 (OMIM: 608541) rho GTPase-activating pro (1738) 11732 1277.5 0
XP_011541377 (OMIM: 608541) PREDICTED: rho GTPase- (1762) 11732 1277.5 0
XP_016874085 (OMIM: 608541) PREDICTED: rho GTPase- (2008) 11732 1277.5 0
XP_016874084 (OMIM: 608541) PREDICTED: rho GTPase- (2061) 11732 1277.5 0
XP_011541374 (OMIM: 608541) PREDICTED: rho GTPase- (2061) 11732 1277.5 0
XP_011541375 (OMIM: 608541) PREDICTED: rho GTPase- (2074) 11732 1277.5 0
NP_001136157 (OMIM: 608541) rho GTPase-activating (2087) 11732 1277.5 0
XP_005271793 (OMIM: 608541) PREDICTED: rho GTPase- (2101) 11732 1277.5 0
XP_016874086 (OMIM: 608541) PREDICTED: rho GTPase- ( 660) 1927 222.2 1.2e-56
XP_011524718 (OMIM: 614902) PREDICTED: rho GTPase- (1161) 1442 170.2 1e-40
XP_011524722 (OMIM: 614902) PREDICTED: rho GTPase- (1162) 1442 170.2 1e-40
XP_006723062 (OMIM: 614902) PREDICTED: rho GTPase- (1298) 1442 170.2 1.1e-40
XP_011524720 (OMIM: 614902) PREDICTED: rho GTPase- (1134) 1424 168.2 3.8e-40
XP_016881727 (OMIM: 614902) PREDICTED: rho GTPase- ( 711) 1337 158.8 1.7e-37
XP_011524721 (OMIM: 614902) PREDICTED: rho GTPase- (1123) 1333 158.4 3.4e-37
NP_001166101 (OMIM: 614902) rho GTPase-activating (1123) 1333 158.4 3.4e-37
XP_011524719 (OMIM: 614902) PREDICTED: rho GTPase- (1152) 1333 158.4 3.4e-37
XP_005258545 (OMIM: 614902) PREDICTED: rho GTPase- (1287) 1333 158.5 3.8e-37
NP_443180 (OMIM: 614902) rho GTPase-activating pro (1126) 1235 147.9 5.1e-34
XP_006713777 (OMIM: 100300,610911) PREDICTED: rho (1424) 1176 141.6 5e-32
NP_065805 (OMIM: 100300,610911) rho GTPase-activat (1444) 1156 139.4 2.3e-31
XP_011524723 (OMIM: 614902) PREDICTED: rho GTPase- ( 703) 1115 134.9 2.6e-30
NP_859071 (OMIM: 614264) rho GTPase-activating pro ( 890) 1032 126.0 1.6e-27
NP_001020769 (OMIM: 614264) rho GTPase-activating (1101) 1027 125.5 2.7e-27
XP_005245127 (OMIM: 614264) PREDICTED: rho GTPase- (1044) 1006 123.2 1.2e-26
XP_016856449 (OMIM: 614264) PREDICTED: rho GTPase- ( 967) 1005 123.1 1.2e-26
NP_954976 (OMIM: 610591) rho GTPase-activating pro ( 548) 428 60.9 3.7e-08
XP_011522776 (OMIM: 610591) PREDICTED: rho GTPase- ( 581) 428 60.9 3.9e-08
XP_016862444 (OMIM: 100300,610911) PREDICTED: rho (1280) 437 62.0 4e-08
XP_005257185 (OMIM: 610591) PREDICTED: rho GTPase- ( 667) 428 61.0 4.4e-08
XP_016879801 (OMIM: 610591) PREDICTED: rho GTPase- ( 689) 428 61.0 4.6e-08
XP_011522774 (OMIM: 610591) PREDICTED: rho GTPase- ( 722) 428 61.0 4.7e-08
XP_011522773 (OMIM: 610591) PREDICTED: rho GTPase- ( 865) 428 61.0 5.5e-08
XP_006721810 (OMIM: 610591) PREDICTED: rho GTPase- ( 867) 428 61.0 5.6e-08
XP_006721808 (OMIM: 610591) PREDICTED: rho GTPase- ( 889) 428 61.0 5.7e-08
NP_001269219 (OMIM: 610591) rho GTPase-activating ( 889) 428 61.0 5.7e-08
XP_011522771 (OMIM: 610591) PREDICTED: rho GTPase- ( 900) 428 61.0 5.7e-08
XP_016879800 (OMIM: 610591) PREDICTED: rho GTPase- ( 922) 428 61.0 5.9e-08
XP_011522770 (OMIM: 610591) PREDICTED: rho GTPase- ( 922) 428 61.0 5.9e-08
XP_011509785 (OMIM: 610578) PREDICTED: rho GTPase- ( 397) 417 59.7 6.4e-08
XP_016859989 (OMIM: 610578) PREDICTED: rho GTPase- ( 432) 417 59.7 6.9e-08
XP_011509781 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 417 59.7 7.5e-08
XP_016859988 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 417 59.7 7.5e-08
NP_060930 (OMIM: 610578) rho GTPase-activating pro ( 475) 417 59.7 7.5e-08
XP_016872443 (OMIM: 610577) PREDICTED: rho GTPase- ( 742) 415 59.6 1.3e-07
NP_001257627 (OMIM: 610577) rho GTPase-activating ( 769) 415 59.6 1.3e-07
XP_011518063 (OMIM: 610577) PREDICTED: rho GTPase- ( 772) 415 59.6 1.3e-07
NP_001257628 (OMIM: 610577) rho GTPase-activating ( 794) 415 59.6 1.4e-07
XP_005252701 (OMIM: 610577) PREDICTED: rho GTPase- ( 794) 415 59.6 1.4e-07
NP_001257626 (OMIM: 610577) rho GTPase-activating ( 799) 415 59.6 1.4e-07
>>NP_055530 (OMIM: 608541) rho GTPase-activating protein (1738 aa)
initn: 11732 init1: 11732 opt: 11732 Z-score: 6833.1 bits: 1277.5 E(85289): 0
Smith-Waterman score: 11732; 100.0% identity (100.0% similar) in 1738 aa overlap (1-1738:1-1738)
10 20 30 40 50 60
pF1KSD MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGEGPAALQGKFHTIIEFPLERKRPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEES
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LTSLHAVDGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LTSLHAVDGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD PALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD SANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD AFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDAT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD NRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD TGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGTSQAGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGTSQAGY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD TNYGDIAVATTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TNYGDIAVATTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD PTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDHVSFPEDQSGK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD NSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDKIYPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDKIYPPS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD GSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KSD PSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPRAMDDPASAFISDSGAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPERPPEPRAMDDPASAFISDSGAAA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KSD AQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAHPCGFPAPLPPTRMMESKMIAAIHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAHPCGFPAPLPPTRMMESKMIAAIHS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KSD SSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKTVYSSFARPDVTTEPFGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKTVYSSFARPDVTTEPFGPD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KSD NCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVAPGRNASGHHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEPPASMGLRYNTYVAPGRNASGHHS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KSD KPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQSLHAPPSSMIRSVPISRTEVPPDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQSLHAPPSSMIRSVPISRTEVPPDDE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KSD PAYCPRPLYQYKPYQSSQARSDYHVTQLQPYFENGRVHYRYSPYSSSSSSYYSPDGALCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PAYCPRPLYQYKPYQSSQARSDYHVTQLQPYFENGRVHYRYSPYSSSSSSYYSPDGALCD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KSD VDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYAGLAPRPRANVTGYFSPNDHNVVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYAGLAPRPRANVTGYFSPNDHNVVSM
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KSD PPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKVKGPVMSQYDNMTPAVQDDLGGIYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKVKGPVMSQYDNMTPAVQDDLGGIYV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KSD IHLRSKSDPGKTGLLSVAEGKESRHAAKAISPEGEDRFYRRHPEAEMDRAHHHGGHGSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IHLRSKSDPGKTGLLSVAEGKESRHAAKAISPEGEDRFYRRHPEAEMDRAHHHGGHGSTQ
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KSD PEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASHRQFCESKNGPPYPQGAGQLDYGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASHRQFCESKNGPPYPQGAGQLDYGSK
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KSD GIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLSKEMERPWVRQPSAPEKHSRDCYKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLSKEMERPWVRQPSAPEKHSRDCYKE
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KSD EEHLTQSIVPPPKPERSHSLKLHHTQNVERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEHLTQSIVPPPKPERSHSLKLHHTQNVERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDY
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730
pF1KSD HSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALGQGAFLPAELSLQHPETQIHAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALGQGAFLPAELSLQHPETQIHAE
1690 1700 1710 1720 1730
>>XP_011541377 (OMIM: 608541) PREDICTED: rho GTPase-acti (1762 aa)
initn: 11732 init1: 11732 opt: 11732 Z-score: 6833.0 bits: 1277.5 E(85289): 0
Smith-Waterman score: 11732; 100.0% identity (100.0% similar) in 1738 aa overlap (1-1738:25-1762)
10 20 30
pF1KSD MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEV
::::::::::::::::::::::::::::::::::::
XP_011 MVERQARIPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KSD PQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KSD CKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KSD LLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHVDV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KSD LFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KSD EGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPS
310 320 330 340 350 360
340 350 360 370 380 390
pF1KSD EMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASFNGEMLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASFNGEMLG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KSD NRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KSD KAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPF
490 500 510 520 530 540
520 530 540 550 560 570
pF1KSD FTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRVSEVIGT
550 560 570 580 590 600
580 590 600 610 620 630
pF1KSD VSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEV
610 620 630 640 650 660
640 650 660 670 680 690
pF1KSD ELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLAL
670 680 690 700 710 720
700 710 720 730 740 750
pF1KSD ALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQTDRPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQTDRPAE
730 740 750 760 770 780
760 770 780 790 800 810
pF1KSD QFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKAR
790 800 810 820 830 840
820 830 840 850 860 870
pF1KSD ITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLH
850 860 870 880 890 900
880 890 900 910 920 930
pF1KSD HPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEASWDVAEQ
910 920 930 940 950 960
940 950 960 970 980 990
pF1KSD PTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVP
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KSD ERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAH
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KSD PCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPLPVPQPK
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KSD HASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSE
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KSD PPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQS
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KSD LHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQPYFENGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQPYFENGR
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KSD VHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYA
1330 1340 1350 1360 1370 1380
1360 1370 1380 1390 1400 1410
pF1KSD GLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKV
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KSD KGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAISPEGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAISPEGED
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KSD RFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASH
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KSD RQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLS
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KSD KEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVERDPSVLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVERDPSVLY
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KSD QYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATAL
1690 1700 1710 1720 1730 1740
1720 1730
pF1KSD GQGAFLPAELSLQHPETQIHAE
::::::::::::::::::::::
XP_011 GQGAFLPAELSLQHPETQIHAE
1750 1760
>>XP_016874085 (OMIM: 608541) PREDICTED: rho GTPase-acti (2008 aa)
initn: 11732 init1: 11732 opt: 11732 Z-score: 6832.1 bits: 1277.5 E(85289): 0
Smith-Waterman score: 11732; 100.0% identity (100.0% similar) in 1738 aa overlap (1-1738:271-2008)
10 20 30
pF1KSD MKSRPTKQKLKQRGILKERVFGCDLGEHLL
::::::::::::::::::::::::::::::
XP_016 NQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLL
250 260 270 280 290 300
40 50 60 70 80 90
pF1KSD NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
310 320 330 340 350 360
100 110 120 130 140 150
pF1KSD HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
370 380 390 400 410 420
160 170 180 190 200 210
pF1KSD LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
430 440 450 460 470 480
220 230 240 250 260 270
pF1KSD LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
490 500 510 520 530 540
280 290 300 310 320 330
pF1KSD KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
550 560 570 580 590 600
340 350 360 370 380 390
pF1KSD NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
610 620 630 640 650 660
400 410 420 430 440 450
pF1KSD NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
670 680 690 700 710 720
460 470 480 490 500 510
pF1KSD FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
730 740 750 760 770 780
520 530 540 550 560 570
pF1KSD EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
790 800 810 820 830 840
580 590 600 610 620 630
pF1KSD SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
850 860 870 880 890 900
640 650 660 670 680 690
pF1KSD VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
910 920 930 940 950 960
700 710 720 730 740 750
pF1KSD ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
970 980 990 1000 1010 1020
760 770 780 790 800 810
pF1KSD TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
1030 1040 1050 1060 1070 1080
820 830 840 850 860 870
pF1KSD DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
1090 1100 1110 1120 1130 1140
880 890 900 910 920 930
pF1KSD SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
1150 1160 1170 1180 1190 1200
940 950 960 970 980 990
pF1KSD WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
1210 1220 1230 1240 1250 1260
1000 1010 1020 1030 1040 1050
pF1KSD GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
1270 1280 1290 1300 1310 1320
1060 1070 1080 1090 1100 1110
pF1KSD ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
1330 1340 1350 1360 1370 1380
1120 1130 1140 1150 1160 1170
pF1KSD PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
1390 1400 1410 1420 1430 1440
1180 1190 1200 1210 1220 1230
pF1KSD YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
1450 1460 1470 1480 1490 1500
1240 1250 1260 1270 1280 1290
pF1KSD IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
1510 1520 1530 1540 1550 1560
1300 1310 1320 1330 1340 1350
pF1KSD YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
1570 1580 1590 1600 1610 1620
1360 1370 1380 1390 1400 1410
pF1KSD SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
1630 1640 1650 1660 1670 1680
1420 1430 1440 1450 1460 1470
pF1KSD RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
1690 1700 1710 1720 1730 1740
1480 1490 1500 1510 1520 1530
pF1KSD SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
1750 1760 1770 1780 1790 1800
1540 1550 1560 1570 1580 1590
pF1KSD HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
1810 1820 1830 1840 1850 1860
1600 1610 1620 1630 1640 1650
pF1KSD KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
1870 1880 1890 1900 1910 1920
1660 1670 1680 1690 1700 1710
pF1KSD DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
1930 1940 1950 1960 1970 1980
1720 1730
pF1KSD TYATALGQGAFLPAELSLQHPETQIHAE
::::::::::::::::::::::::::::
XP_016 TYATALGQGAFLPAELSLQHPETQIHAE
1990 2000
>>XP_016874084 (OMIM: 608541) PREDICTED: rho GTPase-acti (2061 aa)
initn: 11732 init1: 11732 opt: 11732 Z-score: 6832.0 bits: 1277.5 E(85289): 0
Smith-Waterman score: 11732; 100.0% identity (100.0% similar) in 1738 aa overlap (1-1738:324-2061)
10 20 30
pF1KSD MKSRPTKQKLKQRGILKERVFGCDLGEHLL
::::::::::::::::::::::::::::::
XP_016 NQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLL
300 310 320 330 340 350
40 50 60 70 80 90
pF1KSD NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
360 370 380 390 400 410
100 110 120 130 140 150
pF1KSD HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
420 430 440 450 460 470
160 170 180 190 200 210
pF1KSD LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
480 490 500 510 520 530
220 230 240 250 260 270
pF1KSD LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
540 550 560 570 580 590
280 290 300 310 320 330
pF1KSD KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
600 610 620 630 640 650
340 350 360 370 380 390
pF1KSD NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
660 670 680 690 700 710
400 410 420 430 440 450
pF1KSD NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
720 730 740 750 760 770
460 470 480 490 500 510
pF1KSD FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
780 790 800 810 820 830
520 530 540 550 560 570
pF1KSD EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
840 850 860 870 880 890
580 590 600 610 620 630
pF1KSD SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
900 910 920 930 940 950
640 650 660 670 680 690
pF1KSD VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
960 970 980 990 1000 1010
700 710 720 730 740 750
pF1KSD ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
1020 1030 1040 1050 1060 1070
760 770 780 790 800 810
pF1KSD TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
1080 1090 1100 1110 1120 1130
820 830 840 850 860 870
pF1KSD DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
1140 1150 1160 1170 1180 1190
880 890 900 910 920 930
pF1KSD SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
1200 1210 1220 1230 1240 1250
940 950 960 970 980 990
pF1KSD WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
1260 1270 1280 1290 1300 1310
1000 1010 1020 1030 1040 1050
pF1KSD GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
1320 1330 1340 1350 1360 1370
1060 1070 1080 1090 1100 1110
pF1KSD ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
1380 1390 1400 1410 1420 1430
1120 1130 1140 1150 1160 1170
pF1KSD PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
1440 1450 1460 1470 1480 1490
1180 1190 1200 1210 1220 1230
pF1KSD YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
1500 1510 1520 1530 1540 1550
1240 1250 1260 1270 1280 1290
pF1KSD IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
1560 1570 1580 1590 1600 1610
1300 1310 1320 1330 1340 1350
pF1KSD YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
1620 1630 1640 1650 1660 1670
1360 1370 1380 1390 1400 1410
pF1KSD SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
1680 1690 1700 1710 1720 1730
1420 1430 1440 1450 1460 1470
pF1KSD RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
1740 1750 1760 1770 1780 1790
1480 1490 1500 1510 1520 1530
pF1KSD SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
1800 1810 1820 1830 1840 1850
1540 1550 1560 1570 1580 1590
pF1KSD HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
1860 1870 1880 1890 1900 1910
1600 1610 1620 1630 1640 1650
pF1KSD KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
1920 1930 1940 1950 1960 1970
1660 1670 1680 1690 1700 1710
pF1KSD DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
1980 1990 2000 2010 2020 2030
1720 1730
pF1KSD TYATALGQGAFLPAELSLQHPETQIHAE
::::::::::::::::::::::::::::
XP_016 TYATALGQGAFLPAELSLQHPETQIHAE
2040 2050 2060
>>XP_011541374 (OMIM: 608541) PREDICTED: rho GTPase-acti (2061 aa)
initn: 11732 init1: 11732 opt: 11732 Z-score: 6832.0 bits: 1277.5 E(85289): 0
Smith-Waterman score: 11732; 100.0% identity (100.0% similar) in 1738 aa overlap (1-1738:324-2061)
10 20 30
pF1KSD MKSRPTKQKLKQRGILKERVFGCDLGEHLL
::::::::::::::::::::::::::::::
XP_011 NQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLL
300 310 320 330 340 350
40 50 60 70 80 90
pF1KSD NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
360 370 380 390 400 410
100 110 120 130 140 150
pF1KSD HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
420 430 440 450 460 470
160 170 180 190 200 210
pF1KSD LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
480 490 500 510 520 530
220 230 240 250 260 270
pF1KSD LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
540 550 560 570 580 590
280 290 300 310 320 330
pF1KSD KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
600 610 620 630 640 650
340 350 360 370 380 390
pF1KSD NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
660 670 680 690 700 710
400 410 420 430 440 450
pF1KSD NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
720 730 740 750 760 770
460 470 480 490 500 510
pF1KSD FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
780 790 800 810 820 830
520 530 540 550 560 570
pF1KSD EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
840 850 860 870 880 890
580 590 600 610 620 630
pF1KSD SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
900 910 920 930 940 950
640 650 660 670 680 690
pF1KSD VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
960 970 980 990 1000 1010
700 710 720 730 740 750
pF1KSD ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
1020 1030 1040 1050 1060 1070
760 770 780 790 800 810
pF1KSD TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
1080 1090 1100 1110 1120 1130
820 830 840 850 860 870
pF1KSD DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
1140 1150 1160 1170 1180 1190
880 890 900 910 920 930
pF1KSD SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
1200 1210 1220 1230 1240 1250
940 950 960 970 980 990
pF1KSD WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
1260 1270 1280 1290 1300 1310
1000 1010 1020 1030 1040 1050
pF1KSD GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
1320 1330 1340 1350 1360 1370
1060 1070 1080 1090 1100 1110
pF1KSD ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
1380 1390 1400 1410 1420 1430
1120 1130 1140 1150 1160 1170
pF1KSD PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
1440 1450 1460 1470 1480 1490
1180 1190 1200 1210 1220 1230
pF1KSD YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
1500 1510 1520 1530 1540 1550
1240 1250 1260 1270 1280 1290
pF1KSD IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
1560 1570 1580 1590 1600 1610
1300 1310 1320 1330 1340 1350
pF1KSD YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
1620 1630 1640 1650 1660 1670
1360 1370 1380 1390 1400 1410
pF1KSD SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
1680 1690 1700 1710 1720 1730
1420 1430 1440 1450 1460 1470
pF1KSD RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
1740 1750 1760 1770 1780 1790
1480 1490 1500 1510 1520 1530
pF1KSD SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
1800 1810 1820 1830 1840 1850
1540 1550 1560 1570 1580 1590
pF1KSD HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
1860 1870 1880 1890 1900 1910
1600 1610 1620 1630 1640 1650
pF1KSD KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
1920 1930 1940 1950 1960 1970
1660 1670 1680 1690 1700 1710
pF1KSD DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
1980 1990 2000 2010 2020 2030
1720 1730
pF1KSD TYATALGQGAFLPAELSLQHPETQIHAE
::::::::::::::::::::::::::::
XP_011 TYATALGQGAFLPAELSLQHPETQIHAE
2040 2050 2060
>>XP_011541375 (OMIM: 608541) PREDICTED: rho GTPase-acti (2074 aa)
initn: 11732 init1: 11732 opt: 11732 Z-score: 6831.9 bits: 1277.5 E(85289): 0
Smith-Waterman score: 11732; 100.0% identity (100.0% similar) in 1738 aa overlap (1-1738:337-2074)
10 20 30
pF1KSD MKSRPTKQKLKQRGILKERVFGCDLGEHLL
::::::::::::::::::::::::::::::
XP_011 NQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLL
310 320 330 340 350 360
40 50 60 70 80 90
pF1KSD NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
370 380 390 400 410 420
100 110 120 130 140 150
pF1KSD HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
430 440 450 460 470 480
160 170 180 190 200 210
pF1KSD LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
490 500 510 520 530 540
220 230 240 250 260 270
pF1KSD LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
550 560 570 580 590 600
280 290 300 310 320 330
pF1KSD KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
610 620 630 640 650 660
340 350 360 370 380 390
pF1KSD NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
670 680 690 700 710 720
400 410 420 430 440 450
pF1KSD NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
730 740 750 760 770 780
460 470 480 490 500 510
pF1KSD FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
790 800 810 820 830 840
520 530 540 550 560 570
pF1KSD EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
850 860 870 880 890 900
580 590 600 610 620 630
pF1KSD SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
910 920 930 940 950 960
640 650 660 670 680 690
pF1KSD VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
970 980 990 1000 1010 1020
700 710 720 730 740 750
pF1KSD ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
1030 1040 1050 1060 1070 1080
760 770 780 790 800 810
pF1KSD TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
1090 1100 1110 1120 1130 1140
820 830 840 850 860 870
pF1KSD DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
1150 1160 1170 1180 1190 1200
880 890 900 910 920 930
pF1KSD SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
1210 1220 1230 1240 1250 1260
940 950 960 970 980 990
pF1KSD WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
1270 1280 1290 1300 1310 1320
1000 1010 1020 1030 1040 1050
pF1KSD GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
1330 1340 1350 1360 1370 1380
1060 1070 1080 1090 1100 1110
pF1KSD ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
1390 1400 1410 1420 1430 1440
1120 1130 1140 1150 1160 1170
pF1KSD PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
1450 1460 1470 1480 1490 1500
1180 1190 1200 1210 1220 1230
pF1KSD YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
1510 1520 1530 1540 1550 1560
1240 1250 1260 1270 1280 1290
pF1KSD IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
1570 1580 1590 1600 1610 1620
1300 1310 1320 1330 1340 1350
pF1KSD YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
1630 1640 1650 1660 1670 1680
1360 1370 1380 1390 1400 1410
pF1KSD SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
1690 1700 1710 1720 1730 1740
1420 1430 1440 1450 1460 1470
pF1KSD RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
1750 1760 1770 1780 1790 1800
1480 1490 1500 1510 1520 1530
pF1KSD SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
1810 1820 1830 1840 1850 1860
1540 1550 1560 1570 1580 1590
pF1KSD HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
1870 1880 1890 1900 1910 1920
1600 1610 1620 1630 1640 1650
pF1KSD KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
1930 1940 1950 1960 1970 1980
1660 1670 1680 1690 1700 1710
pF1KSD DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
1990 2000 2010 2020 2030 2040
1720 1730
pF1KSD TYATALGQGAFLPAELSLQHPETQIHAE
::::::::::::::::::::::::::::
XP_011 TYATALGQGAFLPAELSLQHPETQIHAE
2050 2060 2070
>>NP_001136157 (OMIM: 608541) rho GTPase-activating prot (2087 aa)
initn: 11732 init1: 11732 opt: 11732 Z-score: 6831.9 bits: 1277.5 E(85289): 0
Smith-Waterman score: 11732; 100.0% identity (100.0% similar) in 1738 aa overlap (1-1738:350-2087)
10 20 30
pF1KSD MKSRPTKQKLKQRGILKERVFGCDLGEHLL
::::::::::::::::::::::::::::::
NP_001 NQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLL
320 330 340 350 360 370
40 50 60 70 80 90
pF1KSD NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
380 390 400 410 420 430
100 110 120 130 140 150
pF1KSD HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
440 450 460 470 480 490
160 170 180 190 200 210
pF1KSD LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
500 510 520 530 540 550
220 230 240 250 260 270
pF1KSD LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
560 570 580 590 600 610
280 290 300 310 320 330
pF1KSD KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
620 630 640 650 660 670
340 350 360 370 380 390
pF1KSD NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
680 690 700 710 720 730
400 410 420 430 440 450
pF1KSD NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
740 750 760 770 780 790
460 470 480 490 500 510
pF1KSD FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
800 810 820 830 840 850
520 530 540 550 560 570
pF1KSD EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
860 870 880 890 900 910
580 590 600 610 620 630
pF1KSD SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
920 930 940 950 960 970
640 650 660 670 680 690
pF1KSD VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
980 990 1000 1010 1020 1030
700 710 720 730 740 750
pF1KSD ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
1040 1050 1060 1070 1080 1090
760 770 780 790 800 810
pF1KSD TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
1100 1110 1120 1130 1140 1150
820 830 840 850 860 870
pF1KSD DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
1160 1170 1180 1190 1200 1210
880 890 900 910 920 930
pF1KSD SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
1220 1230 1240 1250 1260 1270
940 950 960 970 980 990
pF1KSD WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
1280 1290 1300 1310 1320 1330
1000 1010 1020 1030 1040 1050
pF1KSD GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
1340 1350 1360 1370 1380 1390
1060 1070 1080 1090 1100 1110
pF1KSD ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
1400 1410 1420 1430 1440 1450
1120 1130 1140 1150 1160 1170
pF1KSD PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
1460 1470 1480 1490 1500 1510
1180 1190 1200 1210 1220 1230
pF1KSD YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
1520 1530 1540 1550 1560 1570
1240 1250 1260 1270 1280 1290
pF1KSD IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
1580 1590 1600 1610 1620 1630
1300 1310 1320 1330 1340 1350
pF1KSD YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
1640 1650 1660 1670 1680 1690
1360 1370 1380 1390 1400 1410
pF1KSD SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
1700 1710 1720 1730 1740 1750
1420 1430 1440 1450 1460 1470
pF1KSD RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
1760 1770 1780 1790 1800 1810
1480 1490 1500 1510 1520 1530
pF1KSD SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
1820 1830 1840 1850 1860 1870
1540 1550 1560 1570 1580 1590
pF1KSD HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
1880 1890 1900 1910 1920 1930
1600 1610 1620 1630 1640 1650
pF1KSD KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
1940 1950 1960 1970 1980 1990
1660 1670 1680 1690 1700 1710
pF1KSD DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
2000 2010 2020 2030 2040 2050
1720 1730
pF1KSD TYATALGQGAFLPAELSLQHPETQIHAE
::::::::::::::::::::::::::::
NP_001 TYATALGQGAFLPAELSLQHPETQIHAE
2060 2070 2080
>>XP_005271793 (OMIM: 608541) PREDICTED: rho GTPase-acti (2101 aa)
initn: 11732 init1: 11732 opt: 11732 Z-score: 6831.8 bits: 1277.5 E(85289): 0
Smith-Waterman score: 11732; 100.0% identity (100.0% similar) in 1738 aa overlap (1-1738:364-2101)
10 20 30
pF1KSD MKSRPTKQKLKQRGILKERVFGCDLGEHLL
::::::::::::::::::::::::::::::
XP_005 NQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLL
340 350 360 370 380 390
40 50 60 70 80 90
pF1KSD NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
400 410 420 430 440 450
100 110 120 130 140 150
pF1KSD HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
460 470 480 490 500 510
160 170 180 190 200 210
pF1KSD LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
520 530 540 550 560 570
220 230 240 250 260 270
pF1KSD LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
580 590 600 610 620 630
280 290 300 310 320 330
pF1KSD KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
640 650 660 670 680 690
340 350 360 370 380 390
pF1KSD NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAVDGDSKLFRPRRPRSSSDALSASF
700 710 720 730 740 750
400 410 420 430 440 450
pF1KSD NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMS
760 770 780 790 800 810
460 470 480 490 500 510
pF1KSD FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQCSPPKAESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQ
820 830 840 850 860 870
520 530 540 550 560 570
pF1KSD EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIGRKLSKSPSMSISEPISVTLPPRV
880 890 900 910 920 930
580 590 600 610 620 630
pF1KSD SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQ
940 950 960 970 980 990
640 650 660 670 680 690
pF1KSD VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNV
1000 1010 1020 1030 1040 1050
700 710 720 730 740 750
pF1KSD ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIAVATTEDNLSSSYSAVALDKAYFQ
1060 1070 1080 1090 1100 1110
760 770 780 790 800 810
pF1KSD TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSG
1120 1130 1140 1150 1160 1170
820 830 840 850 860 870
pF1KSD DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPEKARITSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGA
1180 1190 1200 1210 1220 1230
880 890 900 910 920 930
pF1KSD SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENTSTATMTYMTTTPATAQMSTKEAS
1240 1250 1260 1270 1280 1290
940 950 960 970 980 990
pF1KSD WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQ
1300 1310 1320 1330 1340 1350
1000 1010 1020 1030 1040 1050
pF1KSD GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRA
1360 1370 1380 1390 1400 1410
1060 1070 1080 1090 1100 1110
pF1KSD ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATSSSNYHSFVTASSTSVDDALPLPL
1420 1430 1440 1450 1460 1470
1120 1130 1140 1150 1160 1170
pF1KSD PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQV
1480 1490 1500 1510 1520 1530
1180 1190 1200 1210 1220 1230
pF1KSD YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGARSEPPASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPT
1540 1550 1560 1570 1580 1590
1240 1250 1260 1270 1280 1290
pF1KSD IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRPLYQYKPYQSSQARSDYHVTQLQP
1600 1610 1620 1630 1640 1650
1300 1310 1320 1330 1340 1350
pF1KSD YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGK
1660 1670 1680 1690 1700 1710
1360 1370 1380 1390 1400 1410
pF1KSD SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLYSYAGLAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRES
1720 1730 1740 1750 1760 1770
1420 1430 1440 1450 1460 1470
pF1KSD RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKSDPGKTGLLSVAEGKESRHAAKAI
1780 1790 1800 1810 1820 1830
1480 1490 1500 1510 1520 1530
pF1KSD SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRA
1840 1850 1860 1870 1880 1890
1540 1550 1560 1570 1580 1590
pF1KSD HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQEASHRQFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNH
1900 1910 1920 1930 1940 1950
1600 1610 1620 1630 1640 1650
pF1KSD KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQSIVPPPKPERSHSLKLHHTQNVER
1960 1970 1980 1990 2000 2010
1660 1670 1680 1690 1700 1710
pF1KSD DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSR
2020 2030 2040 2050 2060 2070
1720 1730
pF1KSD TYATALGQGAFLPAELSLQHPETQIHAE
::::::::::::::::::::::::::::
XP_005 TYATALGQGAFLPAELSLQHPETQIHAE
2080 2090 2100
>>XP_016874086 (OMIM: 608541) PREDICTED: rho GTPase-acti (660 aa)
initn: 1927 init1: 1927 opt: 1927 Z-score: 1137.8 bits: 222.2 E(85289): 1.2e-56
Smith-Waterman score: 1927; 100.0% identity (100.0% similar) in 296 aa overlap (1-296:364-659)
10 20 30
pF1KSD MKSRPTKQKLKQRGILKERVFGCDLGEHLL
::::::::::::::::::::::::::::::
XP_016 NQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLL
340 350 360 370 380 390
40 50 60 70 80 90
pF1KSD NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
400 410 420 430 440 450
100 110 120 130 140 150
pF1KSD HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
460 470 480 490 500 510
160 170 180 190 200 210
pF1KSD LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
520 530 540 550 560 570
220 230 240 250 260 270
pF1KSD LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTEN
580 590 600 610 620 630
280 290 300 310 320 330
pF1KSD KYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQR
::::::::::::::::::::::::::
XP_016 KYIEVGEGPAALQGKFHTIIEFPLERL
640 650 660
>>XP_011524718 (OMIM: 614902) PREDICTED: rho GTPase-acti (1161 aa)
initn: 1443 init1: 1117 opt: 1442 Z-score: 852.0 bits: 170.2 E(85289): 1e-40
Smith-Waterman score: 1614; 36.2% identity (57.4% similar) in 1067 aa overlap (1-1002:157-1105)
10 20 30
pF1KSD MKSRPTKQKLKQRGILKERVFGCDLGEHLL
:.:::..:.:.:::::..:::::::::::
XP_011 CGIPAPQGISSLTSAVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLS
130 140 150 160 170 180
40 50 60 70 80 90
pF1KSD NSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDI
::: .:::::. :. ::: .:.::::::::::.:::::::::::::..:.:. ..:::
XP_011 NSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDI
190 200 210 220 230 240
100 110 120 130 140 150
pF1KSD HSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEF
:::.:::::::::::::::::::: :::.:.:. .::::...::::::::::::::::.
XP_011 HSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEY
250 260 270 280 290 300
160 170 180 190 200 210
pF1KSD LMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFI
:.:::. .: . . :.:::.::::::::::::: ..::. ..:.::: :::.:::::::.
XP_011 LLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAAFREVRVQSVVVEFL
310 320 330 340 350 360
220 230 240 250 260
pF1KSD LNHVDVLFSGRISMAMQEGAAS--LSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVT
:.::::::: .. : . :. : ::::: : :::.::::::::::::.....: :
XP_011 LTHVDVLFSDTFTSAGLDPAGRCLLPRPKSLAGSCPSTRLLTLEEAQARTQGRLGTP--T
370 380 390 400 410 420
270 280 290 300 310 320
pF1KSD ENKYIEVGEGPAALQGKFHTIIEFPLERKRPQNKMK-KSPVGS-WRSFFNLGKSSSVSKR
: .. .:: . . : .:.. . : ..: :: :..:: ::.. :: ..
XP_011 EPTTPKAPASPAERRPP----VSPPNRRRKGERGEKQRKPGGSSWKTFFALGRGPSVPRK
430 440 450 460 470 480
330 340 350 360 370 380
pF1KSD K----LQRNESEPSEMKAMALKGGRAEG-TLRSAKSEESLTSLHAVDGDSKLFRPRRPRS
: : ... :. .:.: . :::::::::::.: . : ..: : :::.:
XP_011 KPLPWLGGTRAPPQP------SGSRPDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHS
490 500 510 520 530
390 400 410 420
pF1KSD SSDAL----SASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALM-SP-H--SA----
::::. . . . : :.. .: .. ... : :.. . :: :: : ::
XP_011 SSDAFPVGPAPAGSCESLSSSSSSESSSSESSSSSSESSAAGLGALSGSPSHRTSAWLDD
540 550 560 570 580 590
430 440 450 460 470 480
pF1KSD -EDVDLSPPDI--GVASLDFDPMSFQCSPPKAESECLESGASFLDSPGYSKDKPSANKKD
...:.::: :. .:::::..:.:: :
XP_011 GDELDFSPPRCLEGLRGLDFDPLTFRCSSP------------------------------
600 610 620
490 500 510 520 530 540
pF1KSD AETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKI
:::. : :.:: .: :. : : . :.::.
XP_011 ---------TPGDPAP--PASP-------------APPAPASAFPPRVTPQ---AISPR-
630 640 650
550 560 570 580 590 600
pF1KSD GRKLSKSPS-MSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPT
: ::. ..::::..:..:: : :..: : .: .:. .::
XP_011 GPTSPASPAALDISEPLAVSVPPAVLELLG------AGGAPASA-------------TPT
660 670 680 690
610 620 630 640 650 660
pF1KSD QIVKMKTNETVAQEAYESEVQPLDQVAAEEVELPGKEDQSVSSSQSKAVASGQTQTGAVT
.. .. . .. :: : : : ... :.. .. . : .
XP_011 PALS-------PGRSLRPHLIPL--------LLRGAEAPLTDACQQEMCSKLRGAQGPLG
700 710 720 730 740
670 680 690 700 710
pF1KSD HDPPQDSVPVSSVSLI-P---PPPPPKNVARMLALALAESAQQASTQSLKR-----PGTS
: .. .: .::. : ::::::: ::..:::::: :::.. :. .. : .:
XP_011 PDM-ESPLPPPPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQECGGTPPAS
750 760 770 780 790 800
720 730 740 750 760 770
pF1KSD QAGYTNYGDIAVATTEDNLSSSY---SAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLP
:. . .. :. . :.: ...: :. : . .... ..:.
XP_011 QSPFHRSLSLEVGGEPLGTSGSGPPPNSLAHPGAWVPGPPPYLPRQQSDGSLLRSQRPMG
810 820 830 840 850 860
780 790 800 810 820 830
pF1KSD ETTATG--DPTH-SNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARITSVPLDSEKSDDH
:. : :.. : ..: ... .. : . : : . .. .: :
XP_011 -TSRRGLRGPAQVSAQLRAGGGGRDAPEAAAQSPCSVPSQVPTPGFFSPAP--RECLPPF
870 880 890 900 910
840 850 860 870 880
pF1KSD VSFPEDQSGKNSMPTVSFLDQDQSP-PRFYSGDQPPSYLGASVDKLHHPLEFADKSP-TP
.. : . : . :: : .:: : . :. ::. : . ..:.. . .. :: .
XP_011 LGVP--KPGLYPLGPPSF--QPSSPAPVWRSSLGPPAPLDRG-ENLYYEIGASEGSPYSG
920 930 940 950 960 970
890 900 910 920 930
pF1KSD P--------NLPSDKIYPPSG----SPEENTSTATMTYMTTTPAT--AQMSTKEASWDVA
: ..: :.. : :: . : . . .:. . : :
XP_011 PTRSWSPFRSMPPDRLNASYGMLGQSPPLHRSPDFLLSYPPAPSCFPPDHLGYSAPQHPA
980 990 1000 1010 1020 1030
940 950 960 970 980
pF1KSD EQPTTADFAAATLQRTHRTNRPLP-----PP--PSQRSAEQPPV--VGQVQAATNIGLNN
..:: . ..: : : :: : .:: ::: . : : : : .
XP_011 RRPTPPEPLYVNLALGPRGPSPASSSSSSPPAHPRSRSDPGPPVPRLPQKQRAP-WGPRT
1040 1050 1060 1070 1080 1090
990 1000 1010 1020 1030 1040
pF1KSD SHKVQGVVPVPERPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPL
:.: : : ::::
XP_011 PHRVPG----PWGPPEPLLLYRAAPPAYGRGGELHRGSLYRNGGQRGEGAGPPPPYPTPS
1100 1110 1120 1130 1140
1738 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 02:45:36 2016 done: Thu Nov 3 02:45:38 2016
Total Scan time: 17.450 Total Display time: 0.830
Function used was FASTA [36.3.4 Apr, 2011]