Result of FASTA (omim) for
pF1KSDA0532
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0532, 1507 aa
1>>>pF1KSDA0532 1507 - 1507 aa - 1507 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4985+/-0.000458; mu= 22.7169+/- 0.029
mean_var=73.3382+/-14.458, 0's: 0 Z-trim(109.8): 37 B-trim: 513 in 1/52
Lambda= 0.149765
statistics sampled from 17984 (18016) to 17984 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.557), E-opt: 0.2 (0.211), width: 16
Scan time: 13.750
The best scores are: opt bits E(85289)
XP_016868601 (OMIM: 216550,607817) PREDICTED: vacu (2541) 10145 2202.7 0
XP_011515156 (OMIM: 216550,607817) PREDICTED: vacu (2615) 10145 2202.7 0
XP_011515153 (OMIM: 216550,607817) PREDICTED: vacu (2984) 10145 2202.7 0
XP_016868600 (OMIM: 216550,607817) PREDICTED: vacu (2984) 10145 2202.7 0
XP_011515154 (OMIM: 216550,607817) PREDICTED: vacu (2984) 10145 2202.7 0
XP_016868599 (OMIM: 216550,607817) PREDICTED: vacu (3617) 10145 2202.8 0
XP_011515152 (OMIM: 216550,607817) PREDICTED: vacu (3896) 10145 2202.8 0
XP_016868598 (OMIM: 216550,607817) PREDICTED: vacu (3957) 10145 2202.8 0
XP_011515151 (OMIM: 216550,607817) PREDICTED: vacu (3996) 10145 2202.8 0
NP_689777 (OMIM: 216550,607817) vacuolar protein s (3997) 10145 2202.8 0
XP_011515150 (OMIM: 216550,607817) PREDICTED: vacu (4021) 10145 2202.8 0
NP_060360 (OMIM: 216550,607817) vacuolar protein s (4022) 10145 2202.8 0
XP_005250857 (OMIM: 216550,607817) PREDICTED: vacu (4022) 10145 2202.8 0
XP_005250858 (OMIM: 216550,607817) PREDICTED: vacu (4022) 10145 2202.8 0
XP_011515155 (OMIM: 216550,607817) PREDICTED: vacu (2725) 1437 321.2 7e-86
NP_060550 (OMIM: 608879,616840) vacuolar protein s (3585) 310 77.8 1.8e-12
NP_001018098 (OMIM: 608879,616840) vacuolar protei (3628) 310 77.8 1.8e-12
NP_060154 (OMIM: 608879,616840) vacuolar protein s (3710) 310 77.8 1.8e-12
NP_065872 (OMIM: 608879,616840) vacuolar protein s (3753) 310 77.8 1.8e-12
NP_001018048 (OMIM: 200150,605978) vacuolar protei (3069) 308 77.3 2.1e-12
NP_056001 (OMIM: 200150,605978) vacuolar protein s (3095) 308 77.3 2.1e-12
NP_001018047 (OMIM: 200150,605978) vacuolar protei (3135) 308 77.3 2.1e-12
NP_150648 (OMIM: 200150,605978) vacuolar protein s (3174) 308 77.3 2.2e-12
NP_060626 (OMIM: 608877) vacuolar protein sorting- (4363) 186 51.0 0.00024
NP_056193 (OMIM: 608877) vacuolar protein sorting- (4388) 186 51.0 0.00024
>>XP_016868601 (OMIM: 216550,607817) PREDICTED: vacuolar (2541 aa)
initn: 10145 init1: 10145 opt: 10145 Z-score: 11831.7 bits: 2202.7 E(85289): 0
Smith-Waterman score: 10145; 100.0% identity (100.0% similar) in 1507 aa overlap (1-1507:1035-2541)
10 20 30
pF1KSD MPSELEYMIVSFREPHMYLRQWNNGSVCQE
::::::::::::::::::::::::::::::
XP_016 AHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQE
1010 1020 1030 1040 1050 1060
40 50 60 70 80 90
pF1KSD IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
1070 1080 1090 1100 1110 1120
100 110 120 130 140 150
pF1KSD VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
1130 1140 1150 1160 1170 1180
160 170 180 190 200 210
pF1KSD RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
1190 1200 1210 1220 1230 1240
220 230 240 250 260 270
pF1KSD IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
1250 1260 1270 1280 1290 1300
280 290 300 310 320 330
pF1KSD VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
1310 1320 1330 1340 1350 1360
340 350 360 370 380 390
pF1KSD LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
1370 1380 1390 1400 1410 1420
400 410 420 430 440 450
pF1KSD DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
1430 1440 1450 1460 1470 1480
460 470 480 490 500 510
pF1KSD PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
1490 1500 1510 1520 1530 1540
520 530 540 550 560 570
pF1KSD FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
1550 1560 1570 1580 1590 1600
580 590 600 610 620 630
pF1KSD KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
1610 1620 1630 1640 1650 1660
640 650 660 670 680 690
pF1KSD SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
1670 1680 1690 1700 1710 1720
700 710 720 730 740 750
pF1KSD VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
1730 1740 1750 1760 1770 1780
760 770 780 790 800 810
pF1KSD LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
1790 1800 1810 1820 1830 1840
820 830 840 850 860 870
pF1KSD EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
1850 1860 1870 1880 1890 1900
880 890 900 910 920 930
pF1KSD TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
1910 1920 1930 1940 1950 1960
940 950 960 970 980 990
pF1KSD EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
1970 1980 1990 2000 2010 2020
1000 1010 1020 1030 1040 1050
pF1KSD CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
2030 2040 2050 2060 2070 2080
1060 1070 1080 1090 1100 1110
pF1KSD QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
2090 2100 2110 2120 2130 2140
1120 1130 1140 1150 1160 1170
pF1KSD TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
2150 2160 2170 2180 2190 2200
1180 1190 1200 1210 1220 1230
pF1KSD PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
2210 2220 2230 2240 2250 2260
1240 1250 1260 1270 1280 1290
pF1KSD SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
2270 2280 2290 2300 2310 2320
1300 1310 1320 1330 1340 1350
pF1KSD FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
2330 2340 2350 2360 2370 2380
1360 1370 1380 1390 1400 1410
pF1KSD PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
2390 2400 2410 2420 2430 2440
1420 1430 1440 1450 1460 1470
pF1KSD LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
2450 2460 2470 2480 2490 2500
1480 1490 1500
pF1KSD PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
:::::::::::::::::::::::::::::::::::::
XP_016 PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
2510 2520 2530 2540
>>XP_011515156 (OMIM: 216550,607817) PREDICTED: vacuolar (2615 aa)
initn: 10145 init1: 10145 opt: 10145 Z-score: 11831.5 bits: 2202.7 E(85289): 0
Smith-Waterman score: 10145; 100.0% identity (100.0% similar) in 1507 aa overlap (1-1507:1109-2615)
10 20 30
pF1KSD MPSELEYMIVSFREPHMYLRQWNNGSVCQE
::::::::::::::::::::::::::::::
XP_011 AHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQE
1080 1090 1100 1110 1120 1130
40 50 60 70 80 90
pF1KSD IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
1140 1150 1160 1170 1180 1190
100 110 120 130 140 150
pF1KSD VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
1200 1210 1220 1230 1240 1250
160 170 180 190 200 210
pF1KSD RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
1260 1270 1280 1290 1300 1310
220 230 240 250 260 270
pF1KSD IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
1320 1330 1340 1350 1360 1370
280 290 300 310 320 330
pF1KSD VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
1380 1390 1400 1410 1420 1430
340 350 360 370 380 390
pF1KSD LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
1440 1450 1460 1470 1480 1490
400 410 420 430 440 450
pF1KSD DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
1500 1510 1520 1530 1540 1550
460 470 480 490 500 510
pF1KSD PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
1560 1570 1580 1590 1600 1610
520 530 540 550 560 570
pF1KSD FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
1620 1630 1640 1650 1660 1670
580 590 600 610 620 630
pF1KSD KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
1680 1690 1700 1710 1720 1730
640 650 660 670 680 690
pF1KSD SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
1740 1750 1760 1770 1780 1790
700 710 720 730 740 750
pF1KSD VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
1800 1810 1820 1830 1840 1850
760 770 780 790 800 810
pF1KSD LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
1860 1870 1880 1890 1900 1910
820 830 840 850 860 870
pF1KSD EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
1920 1930 1940 1950 1960 1970
880 890 900 910 920 930
pF1KSD TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
1980 1990 2000 2010 2020 2030
940 950 960 970 980 990
pF1KSD EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
2040 2050 2060 2070 2080 2090
1000 1010 1020 1030 1040 1050
pF1KSD CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
2100 2110 2120 2130 2140 2150
1060 1070 1080 1090 1100 1110
pF1KSD QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
2160 2170 2180 2190 2200 2210
1120 1130 1140 1150 1160 1170
pF1KSD TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
2220 2230 2240 2250 2260 2270
1180 1190 1200 1210 1220 1230
pF1KSD PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
2280 2290 2300 2310 2320 2330
1240 1250 1260 1270 1280 1290
pF1KSD SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
2340 2350 2360 2370 2380 2390
1300 1310 1320 1330 1340 1350
pF1KSD FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
2400 2410 2420 2430 2440 2450
1360 1370 1380 1390 1400 1410
pF1KSD PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
2460 2470 2480 2490 2500 2510
1420 1430 1440 1450 1460 1470
pF1KSD LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
2520 2530 2540 2550 2560 2570
1480 1490 1500
pF1KSD PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
:::::::::::::::::::::::::::::::::::::
XP_011 PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
2580 2590 2600 2610
>>XP_011515153 (OMIM: 216550,607817) PREDICTED: vacuolar (2984 aa)
initn: 10145 init1: 10145 opt: 10145 Z-score: 11830.6 bits: 2202.7 E(85289): 0
Smith-Waterman score: 10145; 100.0% identity (100.0% similar) in 1507 aa overlap (1-1507:1478-2984)
10 20 30
pF1KSD MPSELEYMIVSFREPHMYLRQWNNGSVCQE
::::::::::::::::::::::::::::::
XP_011 AHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQE
1450 1460 1470 1480 1490 1500
40 50 60 70 80 90
pF1KSD IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
1510 1520 1530 1540 1550 1560
100 110 120 130 140 150
pF1KSD VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
1570 1580 1590 1600 1610 1620
160 170 180 190 200 210
pF1KSD RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
1630 1640 1650 1660 1670 1680
220 230 240 250 260 270
pF1KSD IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
1690 1700 1710 1720 1730 1740
280 290 300 310 320 330
pF1KSD VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
1750 1760 1770 1780 1790 1800
340 350 360 370 380 390
pF1KSD LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
1810 1820 1830 1840 1850 1860
400 410 420 430 440 450
pF1KSD DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
1870 1880 1890 1900 1910 1920
460 470 480 490 500 510
pF1KSD PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
1930 1940 1950 1960 1970 1980
520 530 540 550 560 570
pF1KSD FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
1990 2000 2010 2020 2030 2040
580 590 600 610 620 630
pF1KSD KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
2050 2060 2070 2080 2090 2100
640 650 660 670 680 690
pF1KSD SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
2110 2120 2130 2140 2150 2160
700 710 720 730 740 750
pF1KSD VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
2170 2180 2190 2200 2210 2220
760 770 780 790 800 810
pF1KSD LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
2230 2240 2250 2260 2270 2280
820 830 840 850 860 870
pF1KSD EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
2290 2300 2310 2320 2330 2340
880 890 900 910 920 930
pF1KSD TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
2350 2360 2370 2380 2390 2400
940 950 960 970 980 990
pF1KSD EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
2410 2420 2430 2440 2450 2460
1000 1010 1020 1030 1040 1050
pF1KSD CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
2470 2480 2490 2500 2510 2520
1060 1070 1080 1090 1100 1110
pF1KSD QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
2530 2540 2550 2560 2570 2580
1120 1130 1140 1150 1160 1170
pF1KSD TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
2590 2600 2610 2620 2630 2640
1180 1190 1200 1210 1220 1230
pF1KSD PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
2650 2660 2670 2680 2690 2700
1240 1250 1260 1270 1280 1290
pF1KSD SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
2710 2720 2730 2740 2750 2760
1300 1310 1320 1330 1340 1350
pF1KSD FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
2770 2780 2790 2800 2810 2820
1360 1370 1380 1390 1400 1410
pF1KSD PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
2830 2840 2850 2860 2870 2880
1420 1430 1440 1450 1460 1470
pF1KSD LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
2890 2900 2910 2920 2930 2940
1480 1490 1500
pF1KSD PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
:::::::::::::::::::::::::::::::::::::
XP_011 PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
2950 2960 2970 2980
>>XP_016868600 (OMIM: 216550,607817) PREDICTED: vacuolar (2984 aa)
initn: 10145 init1: 10145 opt: 10145 Z-score: 11830.6 bits: 2202.7 E(85289): 0
Smith-Waterman score: 10145; 100.0% identity (100.0% similar) in 1507 aa overlap (1-1507:1478-2984)
10 20 30
pF1KSD MPSELEYMIVSFREPHMYLRQWNNGSVCQE
::::::::::::::::::::::::::::::
XP_016 AHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQE
1450 1460 1470 1480 1490 1500
40 50 60 70 80 90
pF1KSD IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
1510 1520 1530 1540 1550 1560
100 110 120 130 140 150
pF1KSD VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
1570 1580 1590 1600 1610 1620
160 170 180 190 200 210
pF1KSD RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
1630 1640 1650 1660 1670 1680
220 230 240 250 260 270
pF1KSD IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
1690 1700 1710 1720 1730 1740
280 290 300 310 320 330
pF1KSD VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
1750 1760 1770 1780 1790 1800
340 350 360 370 380 390
pF1KSD LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
1810 1820 1830 1840 1850 1860
400 410 420 430 440 450
pF1KSD DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
1870 1880 1890 1900 1910 1920
460 470 480 490 500 510
pF1KSD PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
1930 1940 1950 1960 1970 1980
520 530 540 550 560 570
pF1KSD FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
1990 2000 2010 2020 2030 2040
580 590 600 610 620 630
pF1KSD KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
2050 2060 2070 2080 2090 2100
640 650 660 670 680 690
pF1KSD SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
2110 2120 2130 2140 2150 2160
700 710 720 730 740 750
pF1KSD VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
2170 2180 2190 2200 2210 2220
760 770 780 790 800 810
pF1KSD LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
2230 2240 2250 2260 2270 2280
820 830 840 850 860 870
pF1KSD EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
2290 2300 2310 2320 2330 2340
880 890 900 910 920 930
pF1KSD TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
2350 2360 2370 2380 2390 2400
940 950 960 970 980 990
pF1KSD EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
2410 2420 2430 2440 2450 2460
1000 1010 1020 1030 1040 1050
pF1KSD CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
2470 2480 2490 2500 2510 2520
1060 1070 1080 1090 1100 1110
pF1KSD QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
2530 2540 2550 2560 2570 2580
1120 1130 1140 1150 1160 1170
pF1KSD TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
2590 2600 2610 2620 2630 2640
1180 1190 1200 1210 1220 1230
pF1KSD PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
2650 2660 2670 2680 2690 2700
1240 1250 1260 1270 1280 1290
pF1KSD SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
2710 2720 2730 2740 2750 2760
1300 1310 1320 1330 1340 1350
pF1KSD FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
2770 2780 2790 2800 2810 2820
1360 1370 1380 1390 1400 1410
pF1KSD PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
2830 2840 2850 2860 2870 2880
1420 1430 1440 1450 1460 1470
pF1KSD LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
2890 2900 2910 2920 2930 2940
1480 1490 1500
pF1KSD PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
:::::::::::::::::::::::::::::::::::::
XP_016 PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
2950 2960 2970 2980
>>XP_011515154 (OMIM: 216550,607817) PREDICTED: vacuolar (2984 aa)
initn: 10145 init1: 10145 opt: 10145 Z-score: 11830.6 bits: 2202.7 E(85289): 0
Smith-Waterman score: 10145; 100.0% identity (100.0% similar) in 1507 aa overlap (1-1507:1478-2984)
10 20 30
pF1KSD MPSELEYMIVSFREPHMYLRQWNNGSVCQE
::::::::::::::::::::::::::::::
XP_011 AHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQE
1450 1460 1470 1480 1490 1500
40 50 60 70 80 90
pF1KSD IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
1510 1520 1530 1540 1550 1560
100 110 120 130 140 150
pF1KSD VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
1570 1580 1590 1600 1610 1620
160 170 180 190 200 210
pF1KSD RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
1630 1640 1650 1660 1670 1680
220 230 240 250 260 270
pF1KSD IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
1690 1700 1710 1720 1730 1740
280 290 300 310 320 330
pF1KSD VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
1750 1760 1770 1780 1790 1800
340 350 360 370 380 390
pF1KSD LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
1810 1820 1830 1840 1850 1860
400 410 420 430 440 450
pF1KSD DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
1870 1880 1890 1900 1910 1920
460 470 480 490 500 510
pF1KSD PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
1930 1940 1950 1960 1970 1980
520 530 540 550 560 570
pF1KSD FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
1990 2000 2010 2020 2030 2040
580 590 600 610 620 630
pF1KSD KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
2050 2060 2070 2080 2090 2100
640 650 660 670 680 690
pF1KSD SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
2110 2120 2130 2140 2150 2160
700 710 720 730 740 750
pF1KSD VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
2170 2180 2190 2200 2210 2220
760 770 780 790 800 810
pF1KSD LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
2230 2240 2250 2260 2270 2280
820 830 840 850 860 870
pF1KSD EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
2290 2300 2310 2320 2330 2340
880 890 900 910 920 930
pF1KSD TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
2350 2360 2370 2380 2390 2400
940 950 960 970 980 990
pF1KSD EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
2410 2420 2430 2440 2450 2460
1000 1010 1020 1030 1040 1050
pF1KSD CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
2470 2480 2490 2500 2510 2520
1060 1070 1080 1090 1100 1110
pF1KSD QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
2530 2540 2550 2560 2570 2580
1120 1130 1140 1150 1160 1170
pF1KSD TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
2590 2600 2610 2620 2630 2640
1180 1190 1200 1210 1220 1230
pF1KSD PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
2650 2660 2670 2680 2690 2700
1240 1250 1260 1270 1280 1290
pF1KSD SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
2710 2720 2730 2740 2750 2760
1300 1310 1320 1330 1340 1350
pF1KSD FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
2770 2780 2790 2800 2810 2820
1360 1370 1380 1390 1400 1410
pF1KSD PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
2830 2840 2850 2860 2870 2880
1420 1430 1440 1450 1460 1470
pF1KSD LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
2890 2900 2910 2920 2930 2940
1480 1490 1500
pF1KSD PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
:::::::::::::::::::::::::::::::::::::
XP_011 PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
2950 2960 2970 2980
>>XP_016868599 (OMIM: 216550,607817) PREDICTED: vacuolar (3617 aa)
initn: 10145 init1: 10145 opt: 10145 Z-score: 11829.4 bits: 2202.8 E(85289): 0
Smith-Waterman score: 10145; 100.0% identity (100.0% similar) in 1507 aa overlap (1-1507:2111-3617)
10 20 30
pF1KSD MPSELEYMIVSFREPHMYLRQWNNGSVCQE
::::::::::::::::::::::::::::::
XP_016 AHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQE
2090 2100 2110 2120 2130 2140
40 50 60 70 80 90
pF1KSD IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
2150 2160 2170 2180 2190 2200
100 110 120 130 140 150
pF1KSD VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
2210 2220 2230 2240 2250 2260
160 170 180 190 200 210
pF1KSD RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
2270 2280 2290 2300 2310 2320
220 230 240 250 260 270
pF1KSD IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
2330 2340 2350 2360 2370 2380
280 290 300 310 320 330
pF1KSD VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
2390 2400 2410 2420 2430 2440
340 350 360 370 380 390
pF1KSD LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
2450 2460 2470 2480 2490 2500
400 410 420 430 440 450
pF1KSD DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
2510 2520 2530 2540 2550 2560
460 470 480 490 500 510
pF1KSD PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
2570 2580 2590 2600 2610 2620
520 530 540 550 560 570
pF1KSD FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
2630 2640 2650 2660 2670 2680
580 590 600 610 620 630
pF1KSD KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
2690 2700 2710 2720 2730 2740
640 650 660 670 680 690
pF1KSD SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
2750 2760 2770 2780 2790 2800
700 710 720 730 740 750
pF1KSD VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
2810 2820 2830 2840 2850 2860
760 770 780 790 800 810
pF1KSD LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
2870 2880 2890 2900 2910 2920
820 830 840 850 860 870
pF1KSD EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
2930 2940 2950 2960 2970 2980
880 890 900 910 920 930
pF1KSD TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
2990 3000 3010 3020 3030 3040
940 950 960 970 980 990
pF1KSD EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
3050 3060 3070 3080 3090 3100
1000 1010 1020 1030 1040 1050
pF1KSD CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
3110 3120 3130 3140 3150 3160
1060 1070 1080 1090 1100 1110
pF1KSD QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
3170 3180 3190 3200 3210 3220
1120 1130 1140 1150 1160 1170
pF1KSD TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
3230 3240 3250 3260 3270 3280
1180 1190 1200 1210 1220 1230
pF1KSD PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
3290 3300 3310 3320 3330 3340
1240 1250 1260 1270 1280 1290
pF1KSD SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
3350 3360 3370 3380 3390 3400
1300 1310 1320 1330 1340 1350
pF1KSD FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
3410 3420 3430 3440 3450 3460
1360 1370 1380 1390 1400 1410
pF1KSD PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
3470 3480 3490 3500 3510 3520
1420 1430 1440 1450 1460 1470
pF1KSD LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
3530 3540 3550 3560 3570 3580
1480 1490 1500
pF1KSD PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
:::::::::::::::::::::::::::::::::::::
XP_016 PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
3590 3600 3610
>>XP_011515152 (OMIM: 216550,607817) PREDICTED: vacuolar (3896 aa)
initn: 10145 init1: 10145 opt: 10145 Z-score: 11828.9 bits: 2202.8 E(85289): 0
Smith-Waterman score: 10145; 100.0% identity (100.0% similar) in 1507 aa overlap (1-1507:2390-3896)
10 20 30
pF1KSD MPSELEYMIVSFREPHMYLRQWNNGSVCQE
::::::::::::::::::::::::::::::
XP_011 AHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQE
2360 2370 2380 2390 2400 2410
40 50 60 70 80 90
pF1KSD IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
2420 2430 2440 2450 2460 2470
100 110 120 130 140 150
pF1KSD VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
2480 2490 2500 2510 2520 2530
160 170 180 190 200 210
pF1KSD RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
2540 2550 2560 2570 2580 2590
220 230 240 250 260 270
pF1KSD IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
2600 2610 2620 2630 2640 2650
280 290 300 310 320 330
pF1KSD VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
2660 2670 2680 2690 2700 2710
340 350 360 370 380 390
pF1KSD LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
2720 2730 2740 2750 2760 2770
400 410 420 430 440 450
pF1KSD DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
2780 2790 2800 2810 2820 2830
460 470 480 490 500 510
pF1KSD PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
2840 2850 2860 2870 2880 2890
520 530 540 550 560 570
pF1KSD FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
2900 2910 2920 2930 2940 2950
580 590 600 610 620 630
pF1KSD KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
2960 2970 2980 2990 3000 3010
640 650 660 670 680 690
pF1KSD SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
3020 3030 3040 3050 3060 3070
700 710 720 730 740 750
pF1KSD VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
3080 3090 3100 3110 3120 3130
760 770 780 790 800 810
pF1KSD LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
3140 3150 3160 3170 3180 3190
820 830 840 850 860 870
pF1KSD EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
3200 3210 3220 3230 3240 3250
880 890 900 910 920 930
pF1KSD TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
3260 3270 3280 3290 3300 3310
940 950 960 970 980 990
pF1KSD EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
3320 3330 3340 3350 3360 3370
1000 1010 1020 1030 1040 1050
pF1KSD CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
3380 3390 3400 3410 3420 3430
1060 1070 1080 1090 1100 1110
pF1KSD QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
3440 3450 3460 3470 3480 3490
1120 1130 1140 1150 1160 1170
pF1KSD TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
3500 3510 3520 3530 3540 3550
1180 1190 1200 1210 1220 1230
pF1KSD PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
3560 3570 3580 3590 3600 3610
1240 1250 1260 1270 1280 1290
pF1KSD SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
3620 3630 3640 3650 3660 3670
1300 1310 1320 1330 1340 1350
pF1KSD FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
3680 3690 3700 3710 3720 3730
1360 1370 1380 1390 1400 1410
pF1KSD PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
3740 3750 3760 3770 3780 3790
1420 1430 1440 1450 1460 1470
pF1KSD LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
3800 3810 3820 3830 3840 3850
1480 1490 1500
pF1KSD PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
:::::::::::::::::::::::::::::::::::::
XP_011 PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
3860 3870 3880 3890
>>XP_016868598 (OMIM: 216550,607817) PREDICTED: vacuolar (3957 aa)
initn: 10145 init1: 10145 opt: 10145 Z-score: 11828.8 bits: 2202.8 E(85289): 0
Smith-Waterman score: 10145; 100.0% identity (100.0% similar) in 1507 aa overlap (1-1507:2451-3957)
10 20 30
pF1KSD MPSELEYMIVSFREPHMYLRQWNNGSVCQE
::::::::::::::::::::::::::::::
XP_016 AHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQE
2430 2440 2450 2460 2470 2480
40 50 60 70 80 90
pF1KSD IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
2490 2500 2510 2520 2530 2540
100 110 120 130 140 150
pF1KSD VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
2550 2560 2570 2580 2590 2600
160 170 180 190 200 210
pF1KSD RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
2610 2620 2630 2640 2650 2660
220 230 240 250 260 270
pF1KSD IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
2670 2680 2690 2700 2710 2720
280 290 300 310 320 330
pF1KSD VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
2730 2740 2750 2760 2770 2780
340 350 360 370 380 390
pF1KSD LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
2790 2800 2810 2820 2830 2840
400 410 420 430 440 450
pF1KSD DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
2850 2860 2870 2880 2890 2900
460 470 480 490 500 510
pF1KSD PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
2910 2920 2930 2940 2950 2960
520 530 540 550 560 570
pF1KSD FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
2970 2980 2990 3000 3010 3020
580 590 600 610 620 630
pF1KSD KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
3030 3040 3050 3060 3070 3080
640 650 660 670 680 690
pF1KSD SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
3090 3100 3110 3120 3130 3140
700 710 720 730 740 750
pF1KSD VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
3150 3160 3170 3180 3190 3200
760 770 780 790 800 810
pF1KSD LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
3210 3220 3230 3240 3250 3260
820 830 840 850 860 870
pF1KSD EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
3270 3280 3290 3300 3310 3320
880 890 900 910 920 930
pF1KSD TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
3330 3340 3350 3360 3370 3380
940 950 960 970 980 990
pF1KSD EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
3390 3400 3410 3420 3430 3440
1000 1010 1020 1030 1040 1050
pF1KSD CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
3450 3460 3470 3480 3490 3500
1060 1070 1080 1090 1100 1110
pF1KSD QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
3510 3520 3530 3540 3550 3560
1120 1130 1140 1150 1160 1170
pF1KSD TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
3570 3580 3590 3600 3610 3620
1180 1190 1200 1210 1220 1230
pF1KSD PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
3630 3640 3650 3660 3670 3680
1240 1250 1260 1270 1280 1290
pF1KSD SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
3690 3700 3710 3720 3730 3740
1300 1310 1320 1330 1340 1350
pF1KSD FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
3750 3760 3770 3780 3790 3800
1360 1370 1380 1390 1400 1410
pF1KSD PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
3810 3820 3830 3840 3850 3860
1420 1430 1440 1450 1460 1470
pF1KSD LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
3870 3880 3890 3900 3910 3920
1480 1490 1500
pF1KSD PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
:::::::::::::::::::::::::::::::::::::
XP_016 PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
3930 3940 3950
>>XP_011515151 (OMIM: 216550,607817) PREDICTED: vacuolar (3996 aa)
initn: 10145 init1: 10145 opt: 10145 Z-score: 11828.8 bits: 2202.8 E(85289): 0
Smith-Waterman score: 10145; 100.0% identity (100.0% similar) in 1507 aa overlap (1-1507:2490-3996)
10 20 30
pF1KSD MPSELEYMIVSFREPHMYLRQWNNGSVCQE
::::::::::::::::::::::::::::::
XP_011 AHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQE
2460 2470 2480 2490 2500 2510
40 50 60 70 80 90
pF1KSD IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
2520 2530 2540 2550 2560 2570
100 110 120 130 140 150
pF1KSD VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
2580 2590 2600 2610 2620 2630
160 170 180 190 200 210
pF1KSD RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
2640 2650 2660 2670 2680 2690
220 230 240 250 260 270
pF1KSD IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
2700 2710 2720 2730 2740 2750
280 290 300 310 320 330
pF1KSD VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
2760 2770 2780 2790 2800 2810
340 350 360 370 380 390
pF1KSD LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
2820 2830 2840 2850 2860 2870
400 410 420 430 440 450
pF1KSD DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
2880 2890 2900 2910 2920 2930
460 470 480 490 500 510
pF1KSD PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
2940 2950 2960 2970 2980 2990
520 530 540 550 560 570
pF1KSD FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
3000 3010 3020 3030 3040 3050
580 590 600 610 620 630
pF1KSD KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
3060 3070 3080 3090 3100 3110
640 650 660 670 680 690
pF1KSD SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
3120 3130 3140 3150 3160 3170
700 710 720 730 740 750
pF1KSD VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
3180 3190 3200 3210 3220 3230
760 770 780 790 800 810
pF1KSD LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
3240 3250 3260 3270 3280 3290
820 830 840 850 860 870
pF1KSD EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
3300 3310 3320 3330 3340 3350
880 890 900 910 920 930
pF1KSD TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
3360 3370 3380 3390 3400 3410
940 950 960 970 980 990
pF1KSD EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
3420 3430 3440 3450 3460 3470
1000 1010 1020 1030 1040 1050
pF1KSD CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
3480 3490 3500 3510 3520 3530
1060 1070 1080 1090 1100 1110
pF1KSD QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
3540 3550 3560 3570 3580 3590
1120 1130 1140 1150 1160 1170
pF1KSD TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
3600 3610 3620 3630 3640 3650
1180 1190 1200 1210 1220 1230
pF1KSD PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
3660 3670 3680 3690 3700 3710
1240 1250 1260 1270 1280 1290
pF1KSD SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
3720 3730 3740 3750 3760 3770
1300 1310 1320 1330 1340 1350
pF1KSD FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
3780 3790 3800 3810 3820 3830
1360 1370 1380 1390 1400 1410
pF1KSD PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
3840 3850 3860 3870 3880 3890
1420 1430 1440 1450 1460 1470
pF1KSD LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
3900 3910 3920 3930 3940 3950
1480 1490 1500
pF1KSD PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
:::::::::::::::::::::::::::::::::::::
XP_011 PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
3960 3970 3980 3990
>>NP_689777 (OMIM: 216550,607817) vacuolar protein sorti (3997 aa)
initn: 10145 init1: 10145 opt: 10145 Z-score: 11828.8 bits: 2202.8 E(85289): 0
Smith-Waterman score: 10145; 100.0% identity (100.0% similar) in 1507 aa overlap (1-1507:2491-3997)
10 20 30
pF1KSD MPSELEYMIVSFREPHMYLRQWNNGSVCQE
::::::::::::::::::::::::::::::
NP_689 AHLEFHLCHHLDQLGTAAPQYLQPFVSDRNMPSELEYMIVSFREPHMYLRQWNNGSVCQE
2470 2480 2490 2500 2510 2520
40 50 60 70 80 90
pF1KSD IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 IQFLAQADCKLLECRNVTMQSVVKPFSIFGQMAVSSDVVEKLLDCTVIVDSVFVNLGQHV
2530 2540 2550 2560 2570 2580
100 110 120 130 140 150
pF1KSD VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 VHSLNTAIQAWQQNKCPEVEELVFSHFVICNDTQETLRFGQVDTDENILLASLHSHQYSW
2590 2600 2610 2620 2630 2640
160 170 180 190 200 210
pF1KSD RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 RSHKSPQLLHICIEGWGNWRWSEPFSVDHAGTFIRTIQYRGRTASLIIKVQQLNGVQKQI
2650 2660 2670 2680 2690 2700
220 230 240 250 260 270
pF1KSD IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 IICGRQIICSYLSQSIELKVVQHYIGQDGQAVVREHFDCLTAKQKLPSYILENNELTELC
2710 2720 2730 2740 2750 2760
280 290 300 310 320 330
pF1KSD VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 VKAKGDEDWSRDVCLESKAPEYSIVIQVPSSNSSIIYVWCTVLTLEPNSQVQQRMIVFSP
2770 2780 2790 2800 2810 2820
340 350 360 370 380 390
pF1KSD LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LFIMRSHLPDPIIIHLEKRSLGLSETQIIPGKGQEKPLQNIEPDLVHHLTFQAREEYDPS
2830 2840 2850 2860 2870 2880
400 410 420 430 440 450
pF1KSD DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DCAVPISTSLIKQIATKVHPGGTVNQILDEFYGPEKSLQPIWPYNKKDSDRNEQLSQWDS
2890 2900 2910 2920 2930 2940
460 470 480 490 500 510
pF1KSD PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PMRVKLSIWKPYVRTLLIELLPWALLINESKWDLWLFEGEKIVLQVPAGKIIIPPNFQEA
2950 2960 2970 2980 2990 3000
520 530 540 550 560 570
pF1KSD FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 FQIGIYWANTNTVHKSVAIKLVHNLTSPKWKDGGNGEVVTLDEEAFVDTEIRLGAFPGHQ
3010 3020 3030 3040 3050 3060
580 590 600 610 620 630
pF1KSD KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KLCQFCISSMVQQGIQIIQIEDKTTIINNTPYQIFYKPQLSVCNPHSGKEYFRVPDSATF
3070 3080 3090 3100 3110 3120
640 650 660 670 680 690
pF1KSD SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SICPGGEQPAMKSSSLPCWDLMPDISQSVLDASLLQKQIMLGFSPAPGADSSQCWSLPAI
3130 3140 3150 3160 3170 3180
700 710 720 730 740 750
pF1KSD VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 VRPEFPRQSVAVPLGNFRENGFCTRAIVLTYQEHLGVTYLTLSEDPSPRVIIHNRCPVKM
3190 3200 3210 3220 3230 3240
760 770 780 790 800 810
pF1KSD LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LIKENIKDIPKFEVYCKKIPSECSIHHELYHQISSYPDCKTKDLLPSLLLRVEPLDEVTT
3250 3260 3270 3280 3290 3300
820 830 840 850 860 870
pF1KSD EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 EWSDAIDINSQGTQVVFLTGFGYVYVDVVHQCGTVFITVAPEGKAGPILTNTNRAPEKIV
3310 3320 3330 3340 3350 3360
880 890 900 910 920 930
pF1KSD TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 TFKMFITQLSLAVFDDLTHHKASAELLRLTLDNIFLCVAPGAGPLPGEEPVAALFELYCV
3370 3380 3390 3400 3410 3420
940 950 960 970 980 990
pF1KSD EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 EICCGDLQLDNQLYNKSNFHFAVLVCQGEKAEPIQCSKMQSLLISNKELEEYKEKCFIKL
3430 3440 3450 3460 3470 3480
1000 1010 1020 1030 1040 1050
pF1KSD CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 CITLNEGKSILCDINEFSFELKPARLYVEDTFVYYIKTLFDTYLPNSRLAGHSTHLSGGK
3490 3500 3510 3520 3530 3540
1060 1070 1080 1090 1100 1110
pF1KSD QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 QVLPMQVTQHARALVNPVKLRKLVIQPVNLLVSIHASLKLYIASDHTPLSFSVFERGPIF
3550 3560 3570 3580 3590 3600
1120 1130 1140 1150 1160 1170
pF1KSD TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 TTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLPYEGLTRG
3610 3620 3630 3640 3650 3660
1180 1190 1200 1210 1220 1230
pF1KSD PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEEWRRQLPE
3670 3680 3690 3700 3710 3720
1240 1250 1260 1270 1280 1290
pF1KSD SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SLGEGLRQGLSRLGISLLGAIAGIVDQPMQNFQKTSEAQASAGHKAKGVISGVGKGIMGV
3730 3740 3750 3760 3770 3780
1300 1310 1320 1330 1340 1350
pF1KSD FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 FTKPIGGAAELVSQTGYGILHGAGLSQLPKQRHQPSDLHADQAPNSHVKYVWKMLQSLGR
3790 3800 3810 3820 3830 3840
1360 1370 1380 1390 1400 1410
pF1KSD PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PEVHMALDVVLVRGSGQEHEGCLLLTSEVLFVVSVSEDTQQQAFPVTEIDCAQDSKQNNL
3850 3860 3870 3880 3890 3900
1420 1430 1440 1450 1460 1470
pF1KSD LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LTVQLKQPRVACDVEVDGVRERLSEQQYNRLVDYITKTSCHLAPSCSSMQIPCPVVAAEP
3910 3920 3930 3940 3950 3960
1480 1490 1500
pF1KSD PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
:::::::::::::::::::::::::::::::::::::
NP_689 PPSTVKTYHYLVDPHFAQVFLSKFTMVKNKALRKGFP
3970 3980 3990
1507 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:58:49 2016 done: Thu Nov 3 01:58:51 2016
Total Scan time: 13.750 Total Display time: 0.970
Function used was FASTA [36.3.4 Apr, 2011]