FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0479, 307 aa
1>>>pF1KSDA0479 307 - 307 aa - 307 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7073+/-0.000973; mu= 13.0842+/- 0.058
mean_var=62.4122+/-12.177, 0's: 0 Z-trim(104.3): 23 B-trim: 0 in 0/50
Lambda= 0.162345
statistics sampled from 7828 (7837) to 7828 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.241), width: 16
Scan time: 2.170
The best scores are: opt bits E(32554)
CCDS1353.1 NMNAT2 gene_id:23057|Hs108|chr1 ( 307) 2073 494.2 5.2e-140
CCDS1354.1 NMNAT2 gene_id:23057|Hs108|chr1 ( 302) 1890 451.4 4.1e-127
CCDS82846.1 NMNAT3 gene_id:349565|Hs108|chr3 ( 252) 435 110.6 1.3e-24
CCDS72698.1 NMNAT1 gene_id:64802|Hs108|chr1 ( 160) 426 108.4 3.7e-24
CCDS108.1 NMNAT1 gene_id:64802|Hs108|chr1 ( 279) 428 108.9 4.5e-24
CCDS3111.1 NMNAT3 gene_id:349565|Hs108|chr3 ( 215) 270 71.9 4.9e-13
>>CCDS1353.1 NMNAT2 gene_id:23057|Hs108|chr1 (307 aa)
initn: 2073 init1: 2073 opt: 2073 Z-score: 2627.2 bits: 494.2 E(32554): 5.2e-140
Smith-Waterman score: 2073; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307)
10 20 30 40 50 60
pF1KSD MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD MNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQ
250 260 270 280 290 300
pF1KSD LYINASG
:::::::
CCDS13 LYINASG
>>CCDS1354.1 NMNAT2 gene_id:23057|Hs108|chr1 (302 aa)
initn: 1890 init1: 1890 opt: 1890 Z-score: 2395.7 bits: 451.4 E(32554): 4.1e-127
Smith-Waterman score: 1890; 98.6% identity (99.3% similar) in 283 aa overlap (25-307:20-302)
10 20 30 40 50 60
pF1KSD MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL
. . ::::::::::::::::::::::::::::::::
CCDS13 MEIQELEEIQACQGLWEVFVTLSERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL
10 20 30 40 50
70 80 90 100 110 120
pF1KSD VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD NLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KSD MNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVIDYILKSQ
240 250 260 270 280 290
pF1KSD LYINASG
:::::::
CCDS13 LYINASG
300
>>CCDS82846.1 NMNAT3 gene_id:349565|Hs108|chr3 (252 aa)
initn: 607 init1: 424 opt: 435 Z-score: 555.2 bits: 110.6 E(32554): 1.3e-24
Smith-Waterman score: 544; 37.3% identity (58.7% similar) in 303 aa overlap (5-306:3-237)
10 20 30 40 50 60
pF1KSD MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL
.. :.:::::::::::. :..::: :::.::.:: . :: ::.:::.:.:::. :
CCDS82 MKSRIPVVLLACGSFNPITNMHLRMFEVARDHLHQTGMYQVIQGIISPVNDTYGKKDL
10 20 30 40 50
70 80 90 100 110 120
pF1KSD VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP
..:.::. : .::.:.:::::::::: : :. : .::.::.. . : .:
CCDS82 AASHHRVAMARLALQTSDWIRVDPWESEQAQWMETVKVLRHHHSKLLR----------SP
60 70 80 90 100
130 140 150 160 170 180
pF1KSD SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA
:: : :. ... . . :.:. :
CCDS82 --------PQMEGPD---HGKALFSTPAAV------------------P-----------
110 120
190 200 210 220 230 240
pF1KSD NLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRI
::. ::::.:.:..: :.::..: .. :: ::.: : : . :
CCDS82 -----------ELK--LLCGADVLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVGHDPKGY
130 140 150 160 170
250 260 270 280 290
pF1KSD MNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYL-SQPVIDYILKS
. .: ::: ...:: ..:. ... .:.: : :: :.:. : :: . :: ::
CCDS82 IAESPILRMHQHNIHLAKEPVQNE---ISATYIRRAL--GQGQSVKYLIPDAVITYIKDH
180 190 200 210 220 230
300
pF1KSD QLYINASG
:: ..:
CCDS82 GLYTKGSTWKGKSTQSTEGKTS
240 250
>>CCDS72698.1 NMNAT1 gene_id:64802|Hs108|chr1 (160 aa)
initn: 419 init1: 419 opt: 426 Z-score: 547.1 bits: 108.4 E(32554): 3.7e-24
Smith-Waterman score: 426; 47.5% identity (78.7% similar) in 122 aa overlap (1-122:1-120)
10 20 30 40 50 60
pF1KSD MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL
: .. ::.:.:::::::::::. :...:: :.::.. :::. :. ::.::: :.: :.::
CCDS72 MENSEKTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGRYTVVKGIISPVGDAYKKKGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP
. . ::.:: .::..:: :..:: :: : :. : .::.::.. .. .. : .. :.:
CCDS72 IPAYHRVIMAELATKNSKWVEVDTWESLQKEWKETLKVLRHHQEKLE-ASDCDHQQ-NSP
70 80 90 100 110
130 140 150 160 170 180
pF1KSD SMTPVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENA
..
CCDS72 TLERPGRKRKWTETQDSSQKKSLEPKTKDGVSLYHPGWSAVA
120 130 140 150 160
>>CCDS108.1 NMNAT1 gene_id:64802|Hs108|chr1 (279 aa)
initn: 632 init1: 419 opt: 428 Z-score: 545.6 bits: 108.9 E(32554): 4.5e-24
Smith-Waterman score: 589; 36.0% identity (62.7% similar) in 308 aa overlap (1-306:1-258)
10 20 30 40 50 60
pF1KSD MTETTKTHVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGL
: .. ::.:.:::::::::::. :...:: :.::.. :::. :. ::.::: :.: :.::
CCDS10 MENSEKTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGRYTVVKGIISPVGDAYKKKGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VSSRHRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTP
. . ::.:: .::..:: :..:: :: : :. : .::.::.. .. .. : .. :.:
CCDS10 IPAYHRVIMAELATKNSKWVEVDTWESLQKEWKETLKVLRHHQEKLE-ASDCDHQQ-NSP
70 80 90 100 110
130 140 150 160 170
pF1KSD SMT-PVIGQPQNETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDEN
.. : . .:: : :.... : :. : :.
CCDS10 TLERPGRKRKWTET-QDSSQKKSLEPKTKAV-----------------PKVK--------
120 130 140 150
180 190 200 210 220 230
pF1KSD ANLGTVMRYEEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDR
::::.:::::: .:.::. :. ::...:.. : : . :...
CCDS10 -----------------LLCGADLLESFAVPNLWKSEDITQIVANYGLICVTRAGNDAQK
160 170 180 190
240 250 260 270 280 290
pF1KSD IMNHSSILRKYKNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYLSQPVI-DYILK
.. .:..: :...:: ::.. : . .:::: : ::..:.. . :: .. .:: :
CCDS10 FIYESDVLWKHRSNIHVVNEWIAND---ISSTKIRRALRRGQS--IRYLVPDLVQEYIEK
200 210 220 230 240 250
300
pF1KSD SQLYINASG
.:: . :
CCDS10 HNLYSSESEDRNAGVILAPLQRNTAEAKT
260 270
>>CCDS3111.1 NMNAT3 gene_id:349565|Hs108|chr3 (215 aa)
initn: 452 init1: 269 opt: 270 Z-score: 347.5 bits: 71.9 E(32554): 4.9e-13
Smith-Waterman score: 379; 33.7% identity (55.1% similar) in 267 aa overlap (41-306:2-200)
20 30 40 50 60 70
pF1KSD LLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSRHRLIMC
. :: ::.:::.:.:::. :..:.::. :
CCDS31 MYQVIQGIISPVNDTYGKKDLAASHHRVAMA
10 20 30
80 90 100 110 120 130
pF1KSD QLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVTGCILSNVNTPSMTPVIGQPQ
.::.:.:::::::::: : :. : .::.::.. . : .: ::
CCDS31 RLALQTSDWIRVDPWESEQAQWMETVKVLRHHHSKLLR--------------SP----PQ
40 50 60 70
140 150 160 170 180 190
pF1KSD NETPQPIYQNSNVATKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRYEE
: :. ... . . :.:. :
CCDS31 MEGPD---HGKALFSTPAAV-----------------P----------------------
80 90
200 210 220 230 240 250
pF1KSD IELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKY
::. ::::.:.:..: :.::..: .. :: ::.: : : . : . .: ::: .
CCDS31 -ELK--LLCGADVLKTFQTPNLWKDAHIQEIVEKFGLVCVGRVGHDPKGYIAESPILRMH
100 110 120 130 140
260 270 280 290 300
pF1KSD KNNIMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDYL-SQPVIDYILKSQLYINASG
..:: ..:. ... .:.: : :: :.:. : :: . :: :: :: ..:
CCDS31 QHNIHLAKEPVQNE---ISATYIRRAL--GQGQSVKYLIPDAVITYIKDHGLYTKGSTWK
150 160 170 180 190 200
CCDS31 GKSTQSTEGKTS
210
307 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:52:41 2016 done: Thu Nov 3 01:52:41 2016
Total Scan time: 2.170 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]