FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0271, 193 aa
1>>>pF1KSDA0271 193 - 193 aa - 193 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9639+/-0.000314; mu= 15.2929+/- 0.020
mean_var=62.3319+/-12.363, 0's: 0 Z-trim(116.3): 44 B-trim: 0 in 0/53
Lambda= 0.162450
statistics sampled from 27283 (27333) to 27283 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.32), width: 16
Scan time: 4.090
The best scores are: opt bits E(85289)
NP_004041 (OMIM: 601931) bcl-2-like protein 2 [Hom ( 193) 1296 311.7 4.7e-85
NP_001186768 (OMIM: 601931) bcl-2-like protein 2 [ ( 193) 1296 311.7 4.7e-85
XP_016883482 (OMIM: 600039) PREDICTED: bcl-2-like ( 233) 530 132.2 6.1e-31
NP_001309169 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 530 132.2 6.1e-31
NP_001304848 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 530 132.2 6.1e-31
NP_001309168 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 530 132.2 6.1e-31
NP_001304849 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 530 132.2 6.1e-31
NP_001304850 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 530 132.2 6.1e-31
XP_011527266 (OMIM: 600039) PREDICTED: bcl-2-like ( 233) 530 132.2 6.1e-31
NP_612815 (OMIM: 600039) bcl-2-like protein 1 isof ( 233) 530 132.2 6.1e-31
NP_001309171 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 530 132.2 6.1e-31
NP_000624 (OMIM: 151430) apoptosis regulator Bcl-2 ( 239) 514 128.5 8.3e-30
XP_011524437 (OMIM: 151430) PREDICTED: apoptosis r ( 224) 437 110.4 2.1e-24
XP_016881406 (OMIM: 151430) PREDICTED: apoptosis r ( 198) 434 109.7 3.1e-24
NP_000648 (OMIM: 151430) apoptosis regulator Bcl-2 ( 205) 434 109.7 3.2e-24
XP_011513082 (OMIM: 600516) PREDICTED: bcl-2 homol ( 152) 210 57.1 1.6e-08
NP_001179 (OMIM: 600516) bcl-2 homologous antagoni ( 211) 210 57.2 2.1e-08
XP_011513081 (OMIM: 600516) PREDICTED: bcl-2 homol ( 211) 210 57.2 2.1e-08
XP_016882566 (OMIM: 600040) PREDICTED: apoptosis r ( 173) 199 54.6 1.1e-07
NP_620116 (OMIM: 600040) apoptosis regulator BAX i ( 192) 199 54.6 1.2e-07
NP_004315 (OMIM: 600040) apoptosis regulator BAX i ( 218) 193 53.2 3.4e-07
NP_620119 (OMIM: 600040) apoptosis regulator BAX i ( 179) 192 52.9 3.4e-07
NP_001278358 (OMIM: 600040) apoptosis regulator BA ( 181) 192 52.9 3.5e-07
NP_001278357 (OMIM: 600040) apoptosis regulator BA ( 221) 192 53.0 4.1e-07
NP_001182 (OMIM: 600039) bcl-2-like protein 1 isof ( 170) 190 52.4 4.6e-07
NP_001278360 (OMIM: 600040) apoptosis regulator BA ( 114) 184 50.9 8.8e-07
NP_620118 (OMIM: 600040) apoptosis regulator BAX i ( 143) 184 51.0 1.1e-06
NP_001278359 (OMIM: 600040) apoptosis regulator BA ( 140) 178 49.6 2.7e-06
NP_115904 (OMIM: 605404) bcl-2-related ovarian kil ( 212) 175 49.0 6.2e-06
XP_011509998 (OMIM: 605404) PREDICTED: bcl-2-relat ( 212) 175 49.0 6.2e-06
NP_001108207 (OMIM: 601056) bcl-2-related protein ( 163) 168 47.3 1.6e-05
NP_004040 (OMIM: 601056) bcl-2-related protein A1 ( 175) 166 46.8 2.3e-05
XP_016860265 (OMIM: 605404) PREDICTED: bcl-2-relat ( 134) 151 43.2 0.00021
XP_016860264 (OMIM: 605404) PREDICTED: bcl-2-relat ( 134) 151 43.2 0.00021
NP_001184249 (OMIM: 159552) induced myeloid leukem ( 197) 148 42.6 0.00047
NP_068779 (OMIM: 159552) induced myeloid leukemia ( 350) 148 42.8 0.00075
>>NP_004041 (OMIM: 601931) bcl-2-like protein 2 [Homo sa (193 aa)
initn: 1296 init1: 1296 opt: 1296 Z-score: 1647.9 bits: 311.7 E(85289): 4.7e-85
Smith-Waterman score: 1296; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KSD MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QVQEWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVQEWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL
130 140 150 160 170 180
190
pF1KSD GALVTVGAFFASK
:::::::::::::
NP_004 GALVTVGAFFASK
190
>>NP_001186768 (OMIM: 601931) bcl-2-like protein 2 [Homo (193 aa)
initn: 1296 init1: 1296 opt: 1296 Z-score: 1647.9 bits: 311.7 E(85289): 4.7e-85
Smith-Waterman score: 1296; 100.0% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KSD MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD QVQEWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVQEWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL
130 140 150 160 170 180
190
pF1KSD GALVTVGAFFASK
:::::::::::::
NP_001 GALVTVGAFFASK
190
>>XP_016883482 (OMIM: 600039) PREDICTED: bcl-2-like prot (233 aa)
initn: 594 init1: 506 opt: 530 Z-score: 676.5 bits: 132.2 E(85289): 6.1e-31
Smith-Waterman score: 530; 51.7% identity (77.5% similar) in 151 aa overlap (37-185:82-231)
10 20 30 40 50 60
pF1KSD APDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA
: : ..::.: :::::: :.::.::::..
XP_016 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMA-AVKQALREAGDEFELRYRRAFSDLTS
60 70 80 90 100 110
70 80 90 100 110 120
pF1KSD QLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWM
:::.:::.: : : :: .:::. : ::::.:::: ::.:::.:::.:::. ::... ::
XP_016 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KSD VAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLRE--GNWASVRTVLTGAVALGALV
..::. .: ::. .::: :. :::..: :.:. .: . : . ...:.: ::.:
XP_016 ATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLF
180 190 200 210 220 230
190
pF1KSD TVGAFFASK
.
XP_016 SRK
>>NP_001309169 (OMIM: 600039) bcl-2-like protein 1 isofo (233 aa)
initn: 594 init1: 506 opt: 530 Z-score: 676.5 bits: 132.2 E(85289): 6.1e-31
Smith-Waterman score: 530; 51.7% identity (77.5% similar) in 151 aa overlap (37-185:82-231)
10 20 30 40 50 60
pF1KSD APDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA
: : ..::.: :::::: :.::.::::..
NP_001 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMA-AVKQALREAGDEFELRYRRAFSDLTS
60 70 80 90 100 110
70 80 90 100 110 120
pF1KSD QLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWM
:::.:::.: : : :: .:::. : ::::.:::: ::.:::.:::.:::. ::... ::
NP_001 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KSD VAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLRE--GNWASVRTVLTGAVALGALV
..::. .: ::. .::: :. :::..: :.:. .: . : . ...:.: ::.:
NP_001 ATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLF
180 190 200 210 220 230
190
pF1KSD TVGAFFASK
.
NP_001 SRK
>>NP_001304848 (OMIM: 600039) bcl-2-like protein 1 isofo (233 aa)
initn: 594 init1: 506 opt: 530 Z-score: 676.5 bits: 132.2 E(85289): 6.1e-31
Smith-Waterman score: 530; 51.7% identity (77.5% similar) in 151 aa overlap (37-185:82-231)
10 20 30 40 50 60
pF1KSD APDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA
: : ..::.: :::::: :.::.::::..
NP_001 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMA-AVKQALREAGDEFELRYRRAFSDLTS
60 70 80 90 100 110
70 80 90 100 110 120
pF1KSD QLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWM
:::.:::.: : : :: .:::. : ::::.:::: ::.:::.:::.:::. ::... ::
NP_001 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KSD VAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLRE--GNWASVRTVLTGAVALGALV
..::. .: ::. .::: :. :::..: :.:. .: . : . ...:.: ::.:
NP_001 ATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLF
180 190 200 210 220 230
190
pF1KSD TVGAFFASK
.
NP_001 SRK
>>NP_001309168 (OMIM: 600039) bcl-2-like protein 1 isofo (233 aa)
initn: 594 init1: 506 opt: 530 Z-score: 676.5 bits: 132.2 E(85289): 6.1e-31
Smith-Waterman score: 530; 51.7% identity (77.5% similar) in 151 aa overlap (37-185:82-231)
10 20 30 40 50 60
pF1KSD APDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA
: : ..::.: :::::: :.::.::::..
NP_001 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMA-AVKQALREAGDEFELRYRRAFSDLTS
60 70 80 90 100 110
70 80 90 100 110 120
pF1KSD QLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWM
:::.:::.: : : :: .:::. : ::::.:::: ::.:::.:::.:::. ::... ::
NP_001 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KSD VAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLRE--GNWASVRTVLTGAVALGALV
..::. .: ::. .::: :. :::..: :.:. .: . : . ...:.: ::.:
NP_001 ATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLF
180 190 200 210 220 230
190
pF1KSD TVGAFFASK
.
NP_001 SRK
>>NP_001304849 (OMIM: 600039) bcl-2-like protein 1 isofo (233 aa)
initn: 594 init1: 506 opt: 530 Z-score: 676.5 bits: 132.2 E(85289): 6.1e-31
Smith-Waterman score: 530; 51.7% identity (77.5% similar) in 151 aa overlap (37-185:82-231)
10 20 30 40 50 60
pF1KSD APDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA
: : ..::.: :::::: :.::.::::..
NP_001 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMA-AVKQALREAGDEFELRYRRAFSDLTS
60 70 80 90 100 110
70 80 90 100 110 120
pF1KSD QLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWM
:::.:::.: : : :: .:::. : ::::.:::: ::.:::.:::.:::. ::... ::
NP_001 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KSD VAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLRE--GNWASVRTVLTGAVALGALV
..::. .: ::. .::: :. :::..: :.:. .: . : . ...:.: ::.:
NP_001 ATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLF
180 190 200 210 220 230
190
pF1KSD TVGAFFASK
.
NP_001 SRK
>>NP_001304850 (OMIM: 600039) bcl-2-like protein 1 isofo (233 aa)
initn: 594 init1: 506 opt: 530 Z-score: 676.5 bits: 132.2 E(85289): 6.1e-31
Smith-Waterman score: 530; 51.7% identity (77.5% similar) in 151 aa overlap (37-185:82-231)
10 20 30 40 50 60
pF1KSD APDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA
: : ..::.: :::::: :.::.::::..
NP_001 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMA-AVKQALREAGDEFELRYRRAFSDLTS
60 70 80 90 100 110
70 80 90 100 110 120
pF1KSD QLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWM
:::.:::.: : : :: .:::. : ::::.:::: ::.:::.:::.:::. ::... ::
NP_001 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KSD VAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLRE--GNWASVRTVLTGAVALGALV
..::. .: ::. .::: :. :::..: :.:. .: . : . ...:.: ::.:
NP_001 ATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLF
180 190 200 210 220 230
190
pF1KSD TVGAFFASK
.
NP_001 SRK
>>XP_011527266 (OMIM: 600039) PREDICTED: bcl-2-like prot (233 aa)
initn: 594 init1: 506 opt: 530 Z-score: 676.5 bits: 132.2 E(85289): 6.1e-31
Smith-Waterman score: 530; 51.7% identity (77.5% similar) in 151 aa overlap (37-185:82-231)
10 20 30 40 50 60
pF1KSD APDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA
: : ..::.: :::::: :.::.::::..
XP_011 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMA-AVKQALREAGDEFELRYRRAFSDLTS
60 70 80 90 100 110
70 80 90 100 110 120
pF1KSD QLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWM
:::.:::.: : : :: .:::. : ::::.:::: ::.:::.:::.:::. ::... ::
XP_011 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KSD VAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLRE--GNWASVRTVLTGAVALGALV
..::. .: ::. .::: :. :::..: :.:. .: . : . ...:.: ::.:
XP_011 ATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLF
180 190 200 210 220 230
190
pF1KSD TVGAFFASK
.
XP_011 SRK
>>NP_612815 (OMIM: 600039) bcl-2-like protein 1 isoform (233 aa)
initn: 594 init1: 506 opt: 530 Z-score: 676.5 bits: 132.2 E(85289): 6.1e-31
Smith-Waterman score: 530; 51.7% identity (77.5% similar) in 151 aa overlap (37-185:82-231)
10 20 30 40 50 60
pF1KSD APDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAA
: : ..::.: :::::: :.::.::::..
NP_612 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMA-AVKQALREAGDEFELRYRRAFSDLTS
60 70 80 90 100 110
70 80 90 100 110 120
pF1KSD QLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWM
:::.:::.: : : :: .:::. : ::::.:::: ::.:::.:::.:::. ::... ::
NP_612 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWM
120 130 140 150 160 170
130 140 150 160 170 180
pF1KSD VAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLRE--GNWASVRTVLTGAVALGALV
..::. .: ::. .::: :. :::..: :.:. .: . : . ...:.: ::.:
NP_612 ATYLNDHLEPWIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLF
180 190 200 210 220 230
190
pF1KSD TVGAFFASK
.
NP_612 SRK
193 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 01:00:37 2016 done: Thu Nov 3 01:00:38 2016
Total Scan time: 4.090 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]