Result of FASTA (omim) for
pF1KSDA0200
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0200, 1016 aa
1>>>pF1KSDA0200 1016 - 1016 aa - 1016 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.5985+/-0.000445; mu= -16.2437+/- 0.027
mean_var=475.0683+/-99.369, 0's: 0 Z-trim(123.2): 49 B-trim: 1471 in 1/61
Lambda= 0.058843
statistics sampled from 42561 (42654) to 42561 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.5), width: 16
Scan time: 13.880
The best scores are: opt bits E(85289)
NP_055572 (OMIM: 605424) mastermind-like protein 1 (1016) 6904 601.3 8.6e-171
NP_061187 (OMIM: 608991) mastermind-like protein 3 (1133) 959 96.6 8e-19
NP_115803 (OMIM: 607537) mastermind-like protein 2 (1156) 526 59.9 9.4e-08
XP_011541327 (OMIM: 607537) PREDICTED: mastermind- ( 735) 427 51.4 2.2e-05
>>NP_055572 (OMIM: 605424) mastermind-like protein 1 [Ho (1016 aa)
initn: 6904 init1: 6904 opt: 6904 Z-score: 3187.2 bits: 601.3 E(85289): 8.6e-171
Smith-Waterman score: 6904; 100.0% identity (100.0% similar) in 1016 aa overlap (1-1016:1-1016)
10 20 30 40 50 60
pF1KSD MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KSD MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KSD IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KSD HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KSD SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA
910 920 930 940 950 960
970 980 990 1000 1010
pF1KSD YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ
970 980 990 1000 1010
>>NP_061187 (OMIM: 608991) mastermind-like protein 3 [Ho (1133 aa)
initn: 1055 init1: 366 opt: 959 Z-score: 459.0 bits: 96.6 E(85289): 8e-19
Smith-Waterman score: 1802; 35.9% identity (63.7% similar) in 1070 aa overlap (12-981:66-1099)
10 20 30 40
pF1KSD MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARY
:.:.::.:.::::.::: ::::: .:: ::
NP_061 TPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRY
40 50 60 70 80 90
50 60 70 80 90 100
pF1KSD EAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHG
. .. :.:::::. : .:.:: .. .::..: .. :. : .::.. ...
NP_061 QQAQVEQLELERRDTVSLYQRTLEQRAKKSGAG----TGKQQHPSKPQQDAEAASAEQRN
100 110 120 130 140 150
110 120 130 140 150
pF1KSD RPATHLHDTVKRNLDSATSPQNGDQQNGY--GDLFPGHKKTRREAPLGV-AI----SSNG
. :..::::.:..: :: ::::::: :.. : :. :.. :. :: :.
NP_061 HTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMP
160 170 180 190 200 210
160 170 180 190 200 210
pF1KSD LPPASPLGQSD-KPSGADALQSSGKHSLGL-DSLNKK-RLADSSLHLNGGSNPSESFPLS
:: :::: : : ::: ::.:: :. :: ..:.:. :: . .: .:: :. .:: .
NP_061 LPSASPLHQLDLKPSL--PLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTIL
220 230 240 250 260
220 230 240 250 260 270
pF1KSD LNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLF
.:.:::::..: :. :. .. .:..:. :.:::.:::.:::.:: .::..:..:::
NP_061 QSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLF
270 280 290 300 310 320
280 290 300 310 320 330
pF1KSD NEDFEEKKDPESSGSATQTPLAQD-INIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPS
::::::::.:: : ::.:::.:. ..:.. : . : . ..::::.: .:.: : :
NP_061 NEDFEEKKEPEFSQPATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPF---S
330 340 350 360 370 380
340 350 360 370 380
pF1KSD SAPVSTDSPSLGGSQTLFHTSGQPR---ADNP-SPNLMPASAQAQNAQRALAGVVL-PS-
.. ..:. ::.... . . ...: ...: .:: : . .: : : .: :.
NP_061 TVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPN--QAHTPGQAPPRPGNGYLLNPAA
390 400 410 420 430 440
390 400 410 420
pF1KSD -------QGPGG--ASELSSAHQLQQIAAKQKR---------------EQMLQNPQQATP
.:: . .:..: :.::.:.::.:.. .:. :. ::
NP_061 VTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQ
450 460 470 480 490 500
430 440 450 460 470 480
pF1KSD APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP
.: :.:. :: : . . ::: :: : : :.:.. .. : .:. . .
NP_061 QQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNN
510 520 530 540 550 560
490 500 510 520 530
pF1KSD YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQ--GSPGSGQSKPA
:: .:.:....:: .::. :: :.: ..: :::::::.:..:: .: : .. .:
NP_061 YLPQNHMNMINQQP-NNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNP
570 580 590 600 610 620
540 550 560 570
pF1KSD LMAYLPQQL------------------------SHISHEQNSLFLMKPKP-GNMP--FRS
:: :. :: .:.:..:. :.::: : :.: . .
NP_061 LMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAA
630 640 650 660 670 680
580 590 600 610 620
pF1KSD LVPPGQEQNPSSVPVQAQATSVGTQPPAVS--VASSHNSSP-YLSSQQQAAVMKQHQLLL
: ::::.: ..: .. . .. ::. . :... ..: .:.:: :::.:: :.:.
NP_061 LPSHGQEQHPVGLP-RTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMK--QMLI
690 700 710 720 730 740
630 640 650 660 670 680
pF1KSD DQQKQREQQQKHL---QQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFP-QQ
::. : .:::. .:.: :.::..::::. : : :: : :. .: .. .: ::
NP_061 DQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQ--QSHL---PRQHLQPQRNPYPVQQ
750 760 770 780 790
690 700 710 720 730 740
pF1KSD VGQFTGSS---AAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRG
:.:: :: ::: .. .: .: :.. : ...: .::.. . ... : ..:.. :
NP_061 VNQFQGSPQDIAAVRSQAALQSMRTS--RLMAQNAGMMGIGPSQ-NPGTMATAAAQSEMG
800 810 820 830 840 850
750 760 770 780 790
pF1KSD VAQFPGSQNMPQSSLYGMASGITQIVAQPPPQA----TNGHAHIPRQTNVGQNTSVSAAY
.: . .. : ..:.:..:.::.. : : :. :...:. ::: ::.... ...
NP_061 LAPY-STTPTSQPGMYNMSTGMTQML-QHPNQSGMSITHNQAQGPRQPASGQGVGMVSGF
860 870 880 890 900 910
800 810 820 830 840 850
pF1KSD GQNSLGSSGLSQQHN--KGTLNPGLTKPPVP-RVSPAMGG--QNS-SWQHQGMPNLSGQT
::. : .:...::: :: .. .: .: .: :.. :: :.. :::.... .. :.:
NP_061 GQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRT
920 930 940 950 960 970
860 870 880 890 900
pF1KSD PGNSNVSPFTAASSFHMQQ-QAHL-KMSSPQ-FSQAV--PNRPMAPMSSAAAVG-SLLPP
: ...::. ..:. .: : .: :. :: .::.: : . . ::.: ...:
NP_061 SG--ELGPFNNGASYPLQAGQPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPS
980 990 1000 1010 1020
910 920 930 940 950 960
pF1KSD VSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQM---GGRAGLHCTQAYP
. .:: :: : . ::: . : . :::: ::.:. :. : .:::
NP_061 LPGQQGTSQARPMV--------MSGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYE
1030 1040 1050 1060 1070 1080
970 980 990 1000 1010
pF1KSD VRTAGQELPFAYSGQ-PGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ
:.: :.. . :::. :::
NP_061 -RNAPQDVSYNYSGDGAGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP
1090 1100 1110 1120 1130
>>NP_115803 (OMIM: 607537) mastermind-like protein 2 [Ho (1156 aa)
initn: 467 init1: 187 opt: 526 Z-score: 260.2 bits: 59.9 E(85289): 9.4e-08
Smith-Waterman score: 809; 27.3% identity (52.6% similar) in 1069 aa overlap (14-906:30-1044)
10 20 30 40
pF1KSD MVLPTCPMAEFALPR-HSAVMERLRRRIELCRRHHSTCEARYEA
:: :::..:::: :: .::.:: .::.:::
NP_115 MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYER
10 20 30 40 50 60
50 60 70 80 90
pF1KSD VSPERLELERQHTFALHQRCIQAK-AKRAGKHRQPPAATA------PAPAAPAPRLDAAD
: . ::. :. : . ... :..:::: . :..: : :::: .::
NP_115 GRAESSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAASQAAA
70 80 90 100 110 120
100 110 120 130 140
pF1KSD GPEHGRPATHLHDTVKRNLDSATS------------PQN--GDQQNGYGDLFPGHKKTRR
: . : .. :.:... : . :::.:. . : : ..
NP_115 TAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQ
130 140 150 160 170 180
150 160 170 180 190
pF1KSD EAPLGVAISS--NGLPPASPLGQS------DKPSGADALQ-SSGKHSL--GLDSLNKKRL
. :. : :. ::. : : . . .: .:: ..:. .. : ... :
NP_115 VVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPL
190 200 210 220 230 240
200 210 220 230 240
pF1KSD ADSSLHLNGGSNPSES-FPLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDL------
.. . .:... : ..: ::.:.:: : : : :...: :..:.
NP_115 RKTNTLPSHTHSPGNGLFNMGL-KEVKKEPGETLSCS-KHMDGQMTQENIFPNRYGDDPG
250 260 270 280 290
250 260 270 280 290
pF1KSD -NLNEQEWKELIEEL-NRSVP---DEDMKDLFNEDFEEKKDP------ESSGSATQTPL-
.: . : .::..:: : ::: : ......: ... :: ..: .: :
NP_115 EQLMDPELQELFNELTNISVPPMSDLELENMINATIKQD-DPFNIDLGQQSQRSTPRPSL
300 310 320 330 340 350
300 310 320 330 340 350
pF1KSD -AQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTS
. : ::.:.::. . : ::::.: ::: .: .:: .::.::
NP_115 PMEKIVIKSEYSPG-LTQGPSGSPQLRPPSAGPAFSMANSA-LSTSSPI-----------
360 370 380 390 400
360 370 380 390 400 410
pF1KSD GQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAA-KQKREQ
:: .: : ::: . :. .::: .:.: :.::.:::: .:.. .
NP_115 -------PS---VPQS-QAQPQTGSGASRALPSW-----QEVSHAQQLKQIAANRQQHAR
410 420 430 440
420 430 440 450 460 470
pF1KSD MLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSV
: :. :: :. . :. .::: . :. .:: ::: .: :. . ::.:
NP_115 MQQHQQQHQPTNWSALPSS---AGPSPG----PFGQEKIPSPSFGQQTFS-PQSSPMPGV
450 460 470 480 490 500
480 490 500 510
pF1KSD NKSSPRP---------GGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLD--YGNTKPLS
.: . .:: : .:...: .: :..:... :: ... ::::::
NP_115 AGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLF
510 520 530 540 550 560
520 530 540 550 560 570
pF1KSD HYKAD-CGQGSPG--SGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFR------
:...: .: :. .:.::.:. : :: .. ...:.. .. . .. .
NP_115 HFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ
570 580 590 600 610 620
580 590 600 610
pF1KSD --SLVPPGQEQNPSSVPVQAQATSVGTQP----------------PAVSVASSHNSSP--
:. :.:. ::. .: : . : :. . :.: :.:
NP_115 QSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLL
630 640 650 660 670 680
pF1KSD ------------------------YLSSQQQ---------------------------AA
: :::: ..
NP_115 RSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSG
690 700 710 720 730 740
620 630 640 650 660 670
pF1KSD VMKQHQLLLDQQ----KQREQQQKHLQQQQFLQRQQHLLAEQEK----QQFQRHLTRPPP
:...: ::.:: :: :.: :.::.: ::..::. :: .:..:::.::::
NP_115 YMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLL-QQQMLADAEKIAPQDQINRHLSRPPP
750 760 770 780 790
680 690 700 710 720
pF1KSD QYQDPTQ--GSFPQQVGQFTGSSAAVPGMNTLGPSNS-SCPRVFPQAGNLMPMGPGHASV
.:.: . :.. : ..:..:.:... .. . .: : .. ..:. . :
NP_115 DYKDQRRNVGNM-QPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHG----
800 810 820 830 840 850
730 740 750 760 770 780
pF1KSD SSLPT-NSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQ---ATNGHAHIPRQ
. .:. ... :. :. :. : . :...::..:.. : :. :.... .::
NP_115 TRMPSLSTAVQNMGMY---GNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRP
860 870 880 890 900 910
790 800 810 820 830 840
pF1KSD TNVG-QNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSS---WQ
..: .:.. :..: .:.:.: :. . .:. .... : :.: .: .:.. :
NP_115 PTLGPSNNNNVATFGAGSVGNS----QQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWA
920 930 940 950 960
850 860 870 880
pF1KSD HQGMPNLSGQTPGNSNVS-PFTAASSFHMQQQAHLKMSSPQFSQ---AVPN--------R
: . . .. ...: : . ... .:. . ..: :::: : :: :
NP_115 SQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMR
970 980 990 1000 1010 1020
890 900 910 920 930 940
pF1KSD PMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQ
:: ::.. :. . :.
NP_115 PMNQMSQTLN-GQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSN
1030 1040 1050 1060 1070 1080
>>XP_011541327 (OMIM: 607537) PREDICTED: mastermind-like (735 aa)
initn: 467 init1: 187 opt: 427 Z-score: 217.6 bits: 51.4 E(85289): 2.2e-05
Smith-Waterman score: 692; 29.9% identity (53.8% similar) in 732 aa overlap (14-674:30-688)
10 20 30 40
pF1KSD MVLPTCPMAEFALPR-HSAVMERLRRRIELCRRHHSTCEARYEA
:: :::..:::: :: .::.:: .::.:::
XP_011 MGDTAPPQAPAGGLGGASGAGLLGGGSVTPRVHSAIVERLRARIAVCRQHHLSCEGRYER
10 20 30 40 50 60
50 60 70 80 90
pF1KSD VSPERLELERQHTFALHQRCIQAK-AKRAGKHRQPPAATA------PAPAAPAPRLDAAD
: . ::. :. : . ... :..:::: . :..: : :::: .::
XP_011 GRAESSDRERESTLQLLSLVQHGQGARKAGKHTKATATAATTTAPPPPPAAPPAASQAAA
70 80 90 100 110 120
100 110 120 130 140
pF1KSD GPEHGRPATHLHDTVKRNLDSATS------------PQN--GDQQNGYGDLFPGHKKTRR
: . : .. :.:... : . :::.:. . : : ..
XP_011 TAAPPPPPDYHHHHQQHLLNSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQ
130 140 150 160 170 180
150 160 170 180 190
pF1KSD EAPLGVAISS--NGLPPASPL-------GQSDKPSGADALQ-SSGKHSL--GLDSLNKKR
. :. : :. ::. : : :. . .: .:: ..:. .. : ...
XP_011 VVNLSPANSKRPNGFVDNSFLDIKRIRVGE-NLSAGQGGLQINNGQSQIMSGTLPMSQAP
190 200 210 220 230
200 210 220 230 240
pF1KSD LADSSLHLNGGSNPSES-FPLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDL-----
: .. . .:... : ..: ::.:.:: : : : :...: :..:.
XP_011 LRKTNTLPSHTHSPGNGLFNMGL-KEVKKEPGETLSCS-KHMDGQMTQENIFPNRYGDDP
240 250 260 270 280 290
250 260 270 280 290
pF1KSD --NLNEQEWKELIEEL-NRSVP---DEDMKDLFNEDFEEKKDP------ESSGSATQTPL
.: . : .::..:: : ::: : ......: ... :: ..: .: :
XP_011 GEQLMDPELQELFNELTNISVPPMSDLELENMINATIKQD-DPFNIDLGQQSQRSTPRPS
300 310 320 330 340 350
300 310 320 330 340 350
pF1KSD --AQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHT
. : ::.:.::. . : ::::.: ::: .: .:: .::.::
XP_011 LPMEKIVIKSEYSPG-LTQGPSGSPQLRPPSAGPAFSMANSA-LSTSSPI----------
360 370 380 390 400
360 370 380 390 400
pF1KSD SGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAA-KQKRE
:: .: : ::: . :. .::: .:.: :.::.:::: .:..
XP_011 --------PS---VPQS-QAQPQTGSGASRALPSW-----QEVSHAQQLKQIAANRQQHA
410 420 430 440
410 420 430 440 450 460
pF1KSD QMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPS
.: :. :: :. . :. .::: . :. .:: ::: .: :. . ::.
XP_011 RMQQHQQQHQPTNWSALPSS---AGPSPG----PFGQEKIPSPSFGQQTFS-PQSSPMPG
450 460 470 480 490
470 480 490 500 510
pF1KSD VNKSSPRP---------GGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLD--YGNTKPL
: .: . .:: : .:...: .: :..:... :: ... ::::::
XP_011 VAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPL
500 510 520 530 540 550
520 530 540 550 560 570
pF1KSD SHYKAD-CGQGSPG--SGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPP
:...: .: :. .:.::.:. : :: .. ...:.. .. .
XP_011 FHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQ------------
560 570 580 590 600
580 590 600 610 620 630
pF1KSD GQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQRE
:.:. .. : : .:...: ..:::... :.: ::.:..
XP_011 -QQQQQQQQQQQQQQSSISAQQ---------------QQQQQSSISAQQQ----QQQQQQ
610 620 630 640
640 650 660 670 680 690
pF1KSD QQQKHLQQQQFLQRQQHLLAEQEKQQF--QRHLTRPPPQYQDPTQGSFPQQVGQFTGSSA
:::.. :::: :.::. . : :.. : : : : :
XP_011 QQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQV
650 660 670 680 690 700
700 710 720 730 740 750
pF1KSD AVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQ
XP_011 SQQQRQQPVGVSMPDADNIESKCSCKGE
710 720 730
1016 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:37:08 2016 done: Thu Nov 3 00:37:10 2016
Total Scan time: 13.880 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]