Result of FASTA (omim) for
pF1KSDA0174
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0174, 364 aa
1>>>pF1KSDA0174 364 - 364 aa - 364 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3043+/-0.000393; mu= -0.1487+/- 0.025
mean_var=285.7682+/-58.043, 0's: 0 Z-trim(121.1): 9 B-trim: 0 in 0/57
Lambda= 0.075870
statistics sampled from 37302 (37311) to 37302 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.437), width: 16
Scan time: 8.240
The best scores are: opt bits E(85289)
NP_001257904 (OMIM: 616434) IST1 homolog isoform a ( 366) 2393 275.0 1.9e-73
NP_001257905 (OMIM: 616434) IST1 homolog isoform c ( 379) 2393 275.0 1.9e-73
NP_055576 (OMIM: 616434) IST1 homolog isoform b [H ( 360) 1863 217.0 5.4e-56
NP_001257906 (OMIM: 616434) IST1 homolog isoform d ( 335) 1654 194.1 4e-49
NP_001257908 (OMIM: 616434) IST1 homolog isoform e ( 218) 1468 173.5 4e-43
NP_001257907 (OMIM: 616434) IST1 homolog isoform e ( 218) 1468 173.5 4e-43
>>NP_001257904 (OMIM: 616434) IST1 homolog isoform a [Ho (366 aa)
initn: 1586 init1: 1550 opt: 2393 Z-score: 1439.6 bits: 275.0 E(85289): 1.9e-73
Smith-Waterman score: 2393; 99.5% identity (99.5% similar) in 366 aa overlap (1-364:1-366)
10 20 30 40 50 60
pF1KSD MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD
130 140 150 160 170 180
190 200 210 220 230
pF1KSD SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMP--S
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPMPS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD ANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD GPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFE
310 320 330 340 350 360
360
pF1KSD ELKKKT
::::::
NP_001 ELKKKT
>>NP_001257905 (OMIM: 616434) IST1 homolog isoform c [Ho (379 aa)
initn: 1586 init1: 1550 opt: 2393 Z-score: 1439.4 bits: 275.0 E(85289): 1.9e-73
Smith-Waterman score: 2393; 99.5% identity (99.5% similar) in 366 aa overlap (1-364:14-379)
10 20 30 40
pF1KSD MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAG
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVFKLKTKEEQHSMLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD KDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD PRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD EIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGT
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD VPMPMPMPMP--SANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDD
:::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPMPMPMPMPMPSANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD INADKNISSAQIVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INADKNISSAQIVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSAS
310 320 330 340 350 360
350 360
pF1KSD EDIDFDDLSRRFEELKKKT
:::::::::::::::::::
NP_001 EDIDFDDLSRRFEELKKKT
370
>>NP_055576 (OMIM: 616434) IST1 homolog isoform b [Homo (360 aa)
initn: 1572 init1: 1550 opt: 1863 Z-score: 1126.2 bits: 217.0 E(85289): 5.4e-56
Smith-Waterman score: 1863; 92.6% identity (94.5% similar) in 310 aa overlap (1-307:1-310)
10 20 30 40 50 60
pF1KSD MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD
130 140 150 160 170 180
190 200 210 220 230
pF1KSD SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMP--S
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_055 SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPMPS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD ANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIV
::::::::::::::::::::::::::::::::::::::::::::. . .. .:
NP_055 ANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESMTLMLIRISLLHRLLV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD -GPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRF
:. :: :
NP_055 LDPSQKPLQSFLPDLQITMTTLSYQSCHLCQTHYQLHLLVPAPQHLKTLTLMIFPGGLKS
310 320 330 340 350 360
>>NP_001257906 (OMIM: 616434) IST1 homolog isoform d [Ho (335 aa)
initn: 1753 init1: 1545 opt: 1654 Z-score: 1003.0 bits: 194.1 E(85289): 4e-49
Smith-Waterman score: 2094; 91.0% identity (91.0% similar) in 366 aa overlap (1-364:1-335)
10 20 30 40 50 60
pF1KSD MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPD
130 140 150 160 170 180
190 200 210 220 230
pF1KSD SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMP--S
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 SVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPMPS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD ANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIV
::::::::::::: ::::::::::::::::
NP_001 ANTPFSYPLPKGP-------------------------------VDDINADKNISSAQIV
250 260
300 310 320 330 340 350
pF1KSD GPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFE
270 280 290 300 310 320
360
pF1KSD ELKKKT
::::::
NP_001 ELKKKT
330
>>NP_001257908 (OMIM: 616434) IST1 homolog isoform e [Ho (218 aa)
initn: 941 init1: 941 opt: 1468 Z-score: 895.3 bits: 173.5 E(85289): 4e-43
Smith-Waterman score: 1468; 99.1% identity (99.1% similar) in 218 aa overlap (149-364:1-218)
120 130 140 150 160 170
pF1KSD IVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYE
::::::::::::::::::::::::::::::
NP_001 MHKLSVEAPPKILVERYLIEIAKNYNVPYE
10 20 30
180 190 200 210 220 230
pF1KSD PDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMP-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPM
40 50 60 70 80 90
240 250 260 270 280 290
pF1KSD -SANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQ
100 110 120 130 140 150
300 310 320 330 340 350
pF1KSD IVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRR
160 170 180 190 200 210
360
pF1KSD FEELKKKT
::::::::
NP_001 FEELKKKT
>>NP_001257907 (OMIM: 616434) IST1 homolog isoform e [Ho (218 aa)
initn: 941 init1: 941 opt: 1468 Z-score: 895.3 bits: 173.5 E(85289): 4e-43
Smith-Waterman score: 1468; 99.1% identity (99.1% similar) in 218 aa overlap (149-364:1-218)
120 130 140 150 160 170
pF1KSD IVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYE
::::::::::::::::::::::::::::::
NP_001 MHKLSVEAPPKILVERYLIEIAKNYNVPYE
10 20 30
180 190 200 210 220 230
pF1KSD PDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMP-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPM
40 50 60 70 80 90
240 250 260 270 280 290
pF1KSD -SANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQ
100 110 120 130 140 150
300 310 320 330 340 350
pF1KSD IVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRR
160 170 180 190 200 210
360
pF1KSD FEELKKKT
::::::::
NP_001 FEELKKKT
364 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 00:28:50 2016 done: Thu Nov 3 00:28:51 2016
Total Scan time: 8.240 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]