Result of FASTA (omim) for
pF1KSDA0053
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0053, 638 aa
1>>>pF1KSDA0053 638 - 638 aa - 638 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7141+/-0.000438; mu= 5.5968+/- 0.027
mean_var=260.9238+/-54.511, 0's: 0 Z-trim(118.8): 358 B-trim: 1055 in 1/53
Lambda= 0.079399
statistics sampled from 31715 (32141) to 31715 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.377), width: 16
Scan time: 9.550
The best scores are: opt bits E(85289)
NP_055697 (OMIM: 610587) rho GTPase-activating pro ( 638) 4247 500.3 8.7e-141
NP_001159748 (OMIM: 610587) rho GTPase-activating ( 639) 4235 498.9 2.3e-140
XP_016860913 (OMIM: 610587) PREDICTED: rho GTPase- ( 649) 4178 492.4 2.1e-138
XP_005264732 (OMIM: 610587) PREDICTED: rho GTPase- ( 645) 4169 491.3 4.3e-138
XP_016860912 (OMIM: 610587) PREDICTED: rho GTPase- ( 650) 4166 491.0 5.5e-138
NP_001007232 (OMIM: 610587) rho GTPase-activating ( 646) 4157 490.0 1.1e-137
XP_011531509 (OMIM: 610587) PREDICTED: rho GTPase- ( 620) 4118 485.5 2.4e-136
XP_011531510 (OMIM: 610587) PREDICTED: rho GTPase- ( 620) 4118 485.5 2.4e-136
XP_011531508 (OMIM: 610587) PREDICTED: rho GTPase- ( 620) 4118 485.5 2.4e-136
XP_005264733 (OMIM: 610587) PREDICTED: rho GTPase- ( 607) 3230 383.8 9.9e-106
XP_016860914 (OMIM: 610587) PREDICTED: rho GTPase- ( 611) 3230 383.8 9.9e-106
NP_001159749 (OMIM: 610587) rho GTPase-activating ( 606) 3228 383.5 1.2e-105
XP_011531511 (OMIM: 610587) PREDICTED: rho GTPase- ( 528) 3226 383.2 1.2e-105
XP_011531512 (OMIM: 610587) PREDICTED: rho GTPase- ( 372) 2426 291.4 3.7e-78
XP_016860915 (OMIM: 610587) PREDICTED: rho GTPase- ( 372) 2426 291.4 3.7e-78
XP_016860916 (OMIM: 610587) PREDICTED: rho GTPase- ( 372) 2426 291.4 3.7e-78
XP_016860917 (OMIM: 610587) PREDICTED: rho GTPase- ( 313) 1713 209.7 1.3e-53
NP_067049 (OMIM: 610585) rho GTPase-activating pro ( 698) 1351 168.6 6.8e-41
XP_011538306 (OMIM: 610585) PREDICTED: rho GTPase- ( 704) 1346 168.0 1e-40
NP_001242954 (OMIM: 610585) rho GTPase-activating ( 704) 1346 168.0 1e-40
NP_001020787 (OMIM: 610586) rho GTPase-activating ( 748) 1239 155.8 5.2e-37
XP_016871965 (OMIM: 610585) PREDICTED: rho GTPase- ( 414) 1181 148.9 3.4e-35
XP_016871962 (OMIM: 610585) PREDICTED: rho GTPase- ( 420) 1176 148.3 5.2e-35
NP_001242955 (OMIM: 610585) rho GTPase-activating ( 608) 1031 131.9 6.7e-30
XP_011538313 (OMIM: 610585) PREDICTED: rho GTPase- ( 565) 962 123.9 1.5e-27
NP_001274734 (OMIM: 610586) rho GTPase-activating ( 663) 963 124.1 1.6e-27
XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 955 123.2 2.8e-27
XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 955 123.2 2.8e-27
XP_011538309 (OMIM: 610585) PREDICTED: rho GTPase- ( 637) 955 123.2 2.9e-27
NP_001242953 (OMIM: 610585) rho GTPase-activating ( 714) 955 123.2 3.1e-27
XP_011538304 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 955 123.2 3.1e-27
XP_011538305 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 955 123.2 3.1e-27
XP_011530602 (OMIM: 610586) PREDICTED: rho GTPase- ( 653) 952 122.8 3.7e-27
NP_001036134 (OMIM: 610586) rho GTPase-activating ( 653) 952 122.8 3.7e-27
XP_016871959 (OMIM: 610585) PREDICTED: rho GTPase- ( 655) 952 122.9 3.7e-27
XP_011538308 (OMIM: 610585) PREDICTED: rho GTPase- ( 661) 952 122.9 3.7e-27
XP_016871961 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 949 122.4 4.2e-27
XP_016871960 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 949 122.4 4.2e-27
XP_011538314 (OMIM: 610585) PREDICTED: rho GTPase- ( 552) 949 122.4 4.2e-27
NP_112595 (OMIM: 610586) rho GTPase-activating pro ( 655) 860 112.3 5.5e-24
XP_011538315 (OMIM: 610585) PREDICTED: rho GTPase- ( 436) 785 103.5 1.6e-21
XP_011538317 (OMIM: 610585) PREDICTED: rho GTPase- ( 359) 775 102.3 3.1e-21
NP_001333022 (OMIM: 610586) rho GTPase-activating ( 555) 537 75.2 6.8e-13
NP_001287881 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 789) 329 51.6 1.3e-05
XP_005277572 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 789) 329 51.6 1.3e-05
XP_005277571 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 790) 329 51.6 1.3e-05
XP_016856330 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 840) 329 51.6 1.3e-05
XP_011507661 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 841) 329 51.6 1.3e-05
XP_016878879 (OMIM: 608293) PREDICTED: rho GTPase- ( 794) 328 51.5 1.4e-05
XP_016856327 (OMIM: 606524) PREDICTED: SLIT-ROBO R ( 931) 329 51.6 1.4e-05
>>NP_055697 (OMIM: 610587) rho GTPase-activating protein (638 aa)
initn: 4247 init1: 4247 opt: 4247 Z-score: 2648.5 bits: 500.3 E(85289): 8.7e-141
Smith-Waterman score: 4247; 100.0% identity (100.0% similar) in 638 aa overlap (1-638:1-638)
10 20 30 40 50 60
pF1KSD MSLGQSACLFLSIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MSLGQSACLFLSIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD SYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD LEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD SVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD NDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPRE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD KPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD QDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSGE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD EEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALE
550 560 570 580 590 600
610 620 630
pF1KSD ISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
::::::::::::::::::::::::::::::::::::::
NP_055 ISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
610 620 630
>>NP_001159748 (OMIM: 610587) rho GTPase-activating prot (639 aa)
initn: 4233 init1: 3226 opt: 4235 Z-score: 2641.1 bits: 498.9 E(85289): 2.3e-140
Smith-Waterman score: 4235; 99.8% identity (99.8% similar) in 639 aa overlap (1-638:1-639)
10 20 30 40 50 60
pF1KSD MSLGQSACLFLSIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLGQSACLFLSIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD FVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQD
70 80 90 100 110 120
130 140 150 160 170
pF1KSD SYVLMASSQAEMEEWVKFLRRVAGTPCG-VFGQRLDETVAYEQKFGPHLVPILVEKCAEF
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_001 SYVLMASSQAEMEEWVKFLRRVAGTPCGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD ILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD VPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD MSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD KNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD EKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTM
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD SQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSG
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD EEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAAL
550 560 570 580 590 600
600 610 620 630
pF1KSD EISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
:::::::::::::::::::::::::::::::::::::::
NP_001 EISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
610 620 630
>>XP_016860913 (OMIM: 610587) PREDICTED: rho GTPase-acti (649 aa)
initn: 4166 init1: 4166 opt: 4178 Z-score: 2605.7 bits: 492.4 E(85289): 2.1e-138
Smith-Waterman score: 4178; 98.7% identity (99.5% similar) in 636 aa overlap (5-638:14-649)
10 20 30 40
pF1KSD MSLGQSACLFLS--IARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQ
...: ::. .::::::::::::::::::::::::::::::::::::
XP_016 MDSISNVDASLHHKNTCSFLGCGLARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD RSIVKNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSIVKNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD ASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD PILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD LYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLH
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD EIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KSD KDIPLSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDIPLSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDA
370 380 390 400 410 420
410 420 430 440 450 460
pF1KSD FPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEA
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD KAGEGHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAGEGHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNS
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD ETGPGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETGPGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEEL
550 560 570 580 590 600
590 600 610 620 630
pF1KSD EKEKKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKEKKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
610 620 630 640
>>XP_005264732 (OMIM: 610587) PREDICTED: rho GTPase-acti (645 aa)
initn: 4169 init1: 4169 opt: 4169 Z-score: 2600.2 bits: 491.3 E(85289): 4.3e-138
Smith-Waterman score: 4169; 100.0% identity (100.0% similar) in 626 aa overlap (13-638:20-645)
10 20 30 40 50
pF1KSD MSLGQSACLFLSIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIV
:::::::::::::::::::::::::::::::::::::::::
XP_005 MSLKLPRNWDFNLKVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD KNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD QNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD EKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD DLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD NCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD LSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPED
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD SSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGE
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD GHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD GKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEK
550 560 570 580 590 600
600 610 620 630
pF1KSD KKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
610 620 630 640
>>XP_016860912 (OMIM: 610587) PREDICTED: rho GTPase-acti (650 aa)
initn: 4152 init1: 3226 opt: 4166 Z-score: 2598.3 bits: 491.0 E(85289): 5.5e-138
Smith-Waterman score: 4166; 98.6% identity (99.4% similar) in 637 aa overlap (5-638:14-650)
10 20 30 40
pF1KSD MSLGQSACLFLS--IARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQ
...: ::. .::::::::::::::::::::::::::::::::::::
XP_016 MDSISNVDASLHHKNTCSFLGCGLARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD RSIVKNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSIVKNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KSD ASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCG-VFGQRLDETVAYEQKFGPHL
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_016 ASWDQNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGAVFGQRLDETVAYEQKFGPHL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KSD VPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KSD KLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KSD HEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPK
310 320 330 340 350 360
350 360 370 380 390 400
pF1KSD SKDIPLSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKDIPLSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSD
370 380 390 400 410 420
410 420 430 440 450 460
pF1KSD AFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSE
430 440 450 460 470 480
470 480 490 500 510 520
pF1KSD AKAGEGHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKAGEGHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPN
490 500 510 520 530 540
530 540 550 560 570 580
pF1KSD SETGPGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SETGPGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEE
550 560 570 580 590 600
590 600 610 620 630
pF1KSD LEKEKKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKEKKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
610 620 630 640 650
>>NP_001007232 (OMIM: 610587) rho GTPase-activating prot (646 aa)
initn: 4155 init1: 3226 opt: 4157 Z-score: 2592.7 bits: 490.0 E(85289): 1.1e-137
Smith-Waterman score: 4157; 99.8% identity (99.8% similar) in 627 aa overlap (13-638:20-646)
10 20 30 40 50
pF1KSD MSLGQSACLFLSIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIV
:::::::::::::::::::::::::::::::::::::::::
NP_001 MSLKLPRNWDFNLKVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD KNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KSD QNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCG-VFGQRLDETVAYEQKFGPHLVPIL
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 QNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGAVFGQRLDETVAYEQKFGPHLVPIL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KSD VEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KSD RDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD LNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD PLSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD DSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD EGHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETG
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD PGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKE
550 560 570 580 590 600
600 610 620 630
pF1KSD KKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
610 620 630 640
>>XP_011531509 (OMIM: 610587) PREDICTED: rho GTPase-acti (620 aa)
initn: 4116 init1: 3226 opt: 4118 Z-score: 2568.8 bits: 485.5 E(85289): 2.4e-136
Smith-Waterman score: 4118; 99.8% identity (99.8% similar) in 620 aa overlap (20-638:1-620)
10 20 30 40 50 60
pF1KSD MSLGQSACLFLSIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRY
:::::::::::::::::::::::::::::::::::::::::
XP_011 MTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRY
10 20 30 40
70 80 90 100 110 120
pF1KSD FVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQD
50 60 70 80 90 100
130 140 150 160 170
pF1KSD SYVLMASSQAEMEEWVKFLRRVAGTPCG-VFGQRLDETVAYEQKFGPHLVPILVEKCAEF
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_011 SYVLMASSQAEMEEWVKFLRRVAGTPCGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEF
110 120 130 140 150 160
180 190 200 210 220 230
pF1KSD ILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KSD VPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KSD MSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KSD KNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPR
350 360 370 380 390 400
420 430 440 450 460 470
pF1KSD EKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTM
410 420 430 440 450 460
480 490 500 510 520 530
pF1KSD SQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSG
470 480 490 500 510 520
540 550 560 570 580 590
pF1KSD EEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAAL
530 540 550 560 570 580
600 610 620 630
pF1KSD EISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
:::::::::::::::::::::::::::::::::::::::
XP_011 EISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
590 600 610 620
>>XP_011531510 (OMIM: 610587) PREDICTED: rho GTPase-acti (620 aa)
initn: 4116 init1: 3226 opt: 4118 Z-score: 2568.8 bits: 485.5 E(85289): 2.4e-136
Smith-Waterman score: 4118; 99.8% identity (99.8% similar) in 620 aa overlap (20-638:1-620)
10 20 30 40 50 60
pF1KSD MSLGQSACLFLSIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRY
:::::::::::::::::::::::::::::::::::::::::
XP_011 MTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRY
10 20 30 40
70 80 90 100 110 120
pF1KSD FVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQD
50 60 70 80 90 100
130 140 150 160 170
pF1KSD SYVLMASSQAEMEEWVKFLRRVAGTPCG-VFGQRLDETVAYEQKFGPHLVPILVEKCAEF
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_011 SYVLMASSQAEMEEWVKFLRRVAGTPCGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEF
110 120 130 140 150 160
180 190 200 210 220 230
pF1KSD ILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KSD VPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KSD MSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KSD KNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPR
350 360 370 380 390 400
420 430 440 450 460 470
pF1KSD EKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTM
410 420 430 440 450 460
480 490 500 510 520 530
pF1KSD SQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSG
470 480 490 500 510 520
540 550 560 570 580 590
pF1KSD EEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAAL
530 540 550 560 570 580
600 610 620 630
pF1KSD EISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
:::::::::::::::::::::::::::::::::::::::
XP_011 EISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
590 600 610 620
>>XP_011531508 (OMIM: 610587) PREDICTED: rho GTPase-acti (620 aa)
initn: 4116 init1: 3226 opt: 4118 Z-score: 2568.8 bits: 485.5 E(85289): 2.4e-136
Smith-Waterman score: 4118; 99.8% identity (99.8% similar) in 620 aa overlap (20-638:1-620)
10 20 30 40 50 60
pF1KSD MSLGQSACLFLSIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRY
:::::::::::::::::::::::::::::::::::::::::
XP_011 MTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRY
10 20 30 40
70 80 90 100 110 120
pF1KSD FVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQD
50 60 70 80 90 100
130 140 150 160 170
pF1KSD SYVLMASSQAEMEEWVKFLRRVAGTPCG-VFGQRLDETVAYEQKFGPHLVPILVEKCAEF
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_011 SYVLMASSQAEMEEWVKFLRRVAGTPCGAVFGQRLDETVAYEQKFGPHLVPILVEKCAEF
110 120 130 140 150 160
180 190 200 210 220 230
pF1KSD ILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KSD VPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KSD MSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KSD KNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPR
350 360 370 380 390 400
420 430 440 450 460 470
pF1KSD EKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTM
410 420 430 440 450 460
480 490 500 510 520 530
pF1KSD SQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSG
470 480 490 500 510 520
540 550 560 570 580 590
pF1KSD EEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAAL
530 540 550 560 570 580
600 610 620 630
pF1KSD EISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
:::::::::::::::::::::::::::::::::::::::
XP_011 EISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
590 600 610 620
>>XP_005264733 (OMIM: 610587) PREDICTED: rho GTPase-acti (607 aa)
initn: 3226 init1: 3226 opt: 3230 Z-score: 2019.2 bits: 383.8 E(85289): 9.9e-106
Smith-Waterman score: 3815; 93.9% identity (93.9% similar) in 626 aa overlap (13-638:20-607)
10 20 30 40 50
pF1KSD MSLGQSACLFLSIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIV
:::::::::::::::::::::::::::::::::::::::::
XP_005 MSLKLPRNWDFNLKVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KSD KNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPA---
70 80 90 100 110
120 130 140 150 160 170
pF1KSD QNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILV
:::::::::::::::::::::::::
XP_005 -----------------------------------VFGQRLDETVAYEQKFGPHLVPILV
120 130 140
180 190 200 210 220 230
pF1KSD EKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLR
150 160 170 180 190 200
240 250 260 270 280 290
pF1KSD DLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQL
210 220 230 240 250 260
300 310 320 330 340 350
pF1KSD NCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIP
270 280 290 300 310 320
360 370 380 390 400 410
pF1KSD LSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPED
330 340 350 360 370 380
420 430 440 450 460 470
pF1KSD SSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGE
390 400 410 420 430 440
480 490 500 510 520 530
pF1KSD GHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGP
450 460 470 480 490 500
540 550 560 570 580 590
pF1KSD GKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEK
510 520 530 540 550 560
600 610 620 630
pF1KSD KKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
570 580 590 600
638 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:39:26 2016 done: Wed Nov 2 23:39:27 2016
Total Scan time: 9.550 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]