FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KF0006, 749 aa 1>>>pF1KF0006 749 - 749 aa - 749 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3944+/-0.000599; mu= 9.3289+/- 0.036 mean_var=237.0174+/-57.572, 0's: 0 Z-trim(111.1): 274 B-trim: 443 in 1/53 Lambda= 0.083308 statistics sampled from 19289 (19644) to 19289 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.23), width: 16 Scan time: 11.080 The best scores are: opt bits E(85289) NP_056520 (OMIM: 610440) small G protein signaling ( 749) 5014 617.7 5.6e-176 XP_005261631 (OMIM: 610440) PREDICTED: small G pro ( 739) 4835 596.1 1.6e-169 XP_016884265 (OMIM: 610440) PREDICTED: small G pro ( 682) 4552 562.1 2.7e-159 XP_016884264 (OMIM: 610440) PREDICTED: small G pro ( 686) 4511 557.2 8.3e-158 XP_011528464 (OMIM: 610440) PREDICTED: small G pro ( 686) 4511 557.2 8.3e-158 XP_005261630 (OMIM: 610440) PREDICTED: small G pro ( 756) 4398 543.6 1.1e-153 XP_005261629 (OMIM: 610440) PREDICTED: small G pro ( 766) 4398 543.6 1.1e-153 XP_016884266 (OMIM: 610440) PREDICTED: small G pro ( 672) 4373 540.6 8.1e-153 XP_005261632 (OMIM: 610440) PREDICTED: small G pro ( 699) 3936 488.1 5.3e-137 XP_016884269 (OMIM: 610440) PREDICTED: small G pro ( 583) 3895 483.0 1.5e-135 XP_011528462 (OMIM: 610440) PREDICTED: small G pro ( 703) 3895 483.1 1.6e-135 XP_011528461 (OMIM: 610440) PREDICTED: small G pro ( 703) 3895 483.1 1.6e-135 XP_016884268 (OMIM: 610440) PREDICTED: small G pro ( 600) 3279 409.0 2.9e-113 XP_011528463 (OMIM: 610440) PREDICTED: small G pro ( 600) 3279 409.0 2.9e-113 NP_001288778 (OMIM: 610440) small G protein signal ( 660) 3086 385.9 2.9e-106 XP_016884267 (OMIM: 610440) PREDICTED: small G pro ( 651) 2995 374.9 5.7e-103 XP_011528460 (OMIM: 610440) PREDICTED: small G pro ( 718) 2995 375.0 6e-103 XP_011517145 (OMIM: 609871) PREDICTED: TBC1 domain ( 468) 659 94.0 1.5e-18 NP_001254501 (OMIM: 609871) TBC1 domain family mem ( 468) 659 94.0 1.5e-18 XP_016870388 (OMIM: 609871) PREDICTED: TBC1 domain ( 483) 659 94.0 1.6e-18 NP_001254500 (OMIM: 609871) TBC1 domain family mem ( 928) 659 94.4 2.3e-18 NP_060891 (OMIM: 609871) TBC1 domain family member ( 917) 582 85.1 1.4e-15 NP_114143 (OMIM: 610020) TBC1 domain family member ( 508) 433 66.9 2.4e-10 NP_001191169 (OMIM: 610020) TBC1 domain family mem ( 515) 433 66.9 2.4e-10 NP_940919 (OMIM: 610831) carabin isoform 1 [Homo s ( 446) 431 66.6 2.6e-10 XP_006718601 (OMIM: 610831) PREDICTED: carabin iso ( 446) 431 66.6 2.6e-10 XP_006718602 (OMIM: 610831) PREDICTED: carabin iso ( 446) 431 66.6 2.6e-10 XP_006718603 (OMIM: 610831) PREDICTED: carabin iso ( 446) 431 66.6 2.6e-10 NP_056342 (OMIM: 613620) TBC1 domain family member ( 808) 423 65.9 7.4e-10 XP_011511972 (OMIM: 609850) PREDICTED: TBC1 domain ( 494) 403 63.3 2.9e-09 XP_006714064 (OMIM: 609850) PREDICTED: TBC1 domain ( 546) 403 63.3 3.1e-09 XP_016876373 (OMIM: 612465,616087) PREDICTED: TBC1 ( 487) 398 62.6 4.3e-09 XP_016863410 (OMIM: 609850) PREDICTED: TBC1 domain (1039) 403 63.7 4.5e-09 XP_005262706 (OMIM: 609850) PREDICTED: TBC1 domain (1146) 403 63.7 4.8e-09 NP_055988 (OMIM: 609850) TBC1 domain family member (1168) 403 63.7 4.9e-09 XP_016863409 (OMIM: 609850) PREDICTED: TBC1 domain (1181) 403 63.7 4.9e-09 XP_011511968 (OMIM: 609850) PREDICTED: TBC1 domain (1188) 403 63.7 4.9e-09 XP_011511967 (OMIM: 609850) PREDICTED: TBC1 domain (1201) 403 63.7 5e-09 XP_016863408 (OMIM: 609850) PREDICTED: TBC1 domain (1222) 403 63.8 5e-09 XP_016863407 (OMIM: 609850) PREDICTED: TBC1 domain (1228) 403 63.8 5e-09 XP_011511966 (OMIM: 609850) PREDICTED: TBC1 domain (1241) 403 63.8 5.1e-09 XP_011511965 (OMIM: 609850) PREDICTED: TBC1 domain (1242) 403 63.8 5.1e-09 XP_011511964 (OMIM: 609850) PREDICTED: TBC1 domain (1255) 403 63.8 5.1e-09 XP_005262704 (OMIM: 609850) PREDICTED: TBC1 domain (1262) 403 63.8 5.1e-09 XP_005262703 (OMIM: 609850) PREDICTED: TBC1 domain (1275) 403 63.8 5.2e-09 XP_011511962 (OMIM: 609850) PREDICTED: TBC1 domain (1282) 403 63.8 5.2e-09 XP_011511961 (OMIM: 609850) PREDICTED: TBC1 domain (1295) 403 63.8 5.2e-09 XP_016876372 (OMIM: 612465,616087) PREDICTED: TBC1 (1017) 398 63.0 6.8e-09 XP_016876371 (OMIM: 612465,616087) PREDICTED: TBC1 (1054) 398 63.1 7e-09 XP_005266662 (OMIM: 612465,616087) PREDICTED: TBC1 (1117) 398 63.1 7.2e-09 >>NP_056520 (OMIM: 610440) small G protein signaling mod (749 aa) initn: 5014 init1: 5014 opt: 5014 Z-score: 3280.4 bits: 617.7 E(85289): 5.6e-176 Smith-Waterman score: 5014; 100.0% identity (100.0% similar) in 749 aa overlap (1-749:1-749) 10 20 30 40 50 60 pF1KF0 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 LLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 PQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 PQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 VPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 VPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 LLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 FFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 LTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 LKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 HRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDER 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 SKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 SKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 ERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 ERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KF0 GLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 GLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELP 670 680 690 700 710 720 730 740 pF1KF0 AKREAQQPLKEGVRDMLVKHHLFSWDVDG ::::::::::::::::::::::::::::: NP_056 AKREAQQPLKEGVRDMLVKHHLFSWDVDG 730 740 >>XP_005261631 (OMIM: 610440) PREDICTED: small G protein (739 aa) initn: 4835 init1: 4835 opt: 4835 Z-score: 3164.2 bits: 596.1 E(85289): 1.6e-169 Smith-Waterman score: 4835; 100.0% identity (100.0% similar) in 724 aa overlap (1-724:1-724) 10 20 30 40 50 60 pF1KF0 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 LLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 PQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 VPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 LLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 FFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 LTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 LKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 HRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDER 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 SKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 ERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KF0 GLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELP 670 680 690 700 710 720 730 740 pF1KF0 AKREAQQPLKEGVRDMLVKHHLFSWDVDG :::: XP_005 AKRELGLQSCIQVQGSALP 730 >>XP_016884265 (OMIM: 610440) PREDICTED: small G protein (682 aa) initn: 4552 init1: 4552 opt: 4552 Z-score: 2980.8 bits: 562.1 E(85289): 2.7e-159 Smith-Waterman score: 4552; 100.0% identity (100.0% similar) in 682 aa overlap (68-749:1-682) 40 50 60 70 80 90 pF1KF0 PEFYYDEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKI :::::::::::::::::::::::::::::: XP_016 MEDAPQRLRWQAHLEFTHNHDVGDLTWDKI 10 20 30 100 110 120 130 140 150 pF1KF0 AVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAK 40 50 60 70 80 90 160 170 180 190 200 210 pF1KF0 QIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEE 100 110 120 130 140 150 220 230 240 250 260 270 pF1KF0 EDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLIT 160 170 180 190 200 210 280 290 300 310 320 330 pF1KF0 LHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KF0 SDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVV 280 290 300 310 320 330 400 410 420 430 440 450 pF1KF0 RRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVE 340 350 360 370 380 390 460 470 480 490 500 510 pF1KF0 LTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHC 400 410 420 430 440 450 520 530 540 550 560 570 pF1KF0 WVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLK 460 470 480 490 500 510 580 590 600 610 620 630 pF1KF0 KPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQ 520 530 540 550 560 570 640 650 660 670 680 690 pF1KF0 SVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWV 580 590 600 610 620 630 700 710 720 730 740 pF1KF0 QIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG 640 650 660 670 680 >>XP_016884264 (OMIM: 610440) PREDICTED: small G protein (686 aa) initn: 4511 init1: 4511 opt: 4511 Z-score: 2954.1 bits: 557.2 E(85289): 8.3e-158 Smith-Waterman score: 4511; 99.9% identity (100.0% similar) in 677 aa overlap (73-749:10-686) 50 60 70 80 90 100 pF1KF0 DEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLP .::::::::::::::::::::::::::::: XP_016 MSLVSVCTRKRLRWQAHLEFTHNHDVGDLTWDKIAVSLP 10 20 30 110 120 130 140 150 160 pF1KF0 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 40 50 60 70 80 90 170 180 190 200 210 220 pF1KF0 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 100 110 120 130 140 150 230 240 250 260 270 280 pF1KF0 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KF0 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS 220 230 240 250 260 270 350 360 370 380 390 400 pF1KF0 QMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQ 280 290 300 310 320 330 410 420 430 440 450 460 pF1KF0 RRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDY 340 350 360 370 380 390 470 480 490 500 510 520 pF1KF0 SMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGEL 400 410 420 430 440 450 530 540 550 560 570 580 pF1KF0 NGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLL 460 470 480 490 500 510 590 600 610 620 630 640 pF1KF0 GGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVT 520 530 540 550 560 570 650 660 670 680 690 700 pF1KF0 HDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCE 580 590 600 610 620 630 710 720 730 740 pF1KF0 LRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG 640 650 660 670 680 >>XP_011528464 (OMIM: 610440) PREDICTED: small G protein (686 aa) initn: 4511 init1: 4511 opt: 4511 Z-score: 2954.1 bits: 557.2 E(85289): 8.3e-158 Smith-Waterman score: 4511; 99.9% identity (100.0% similar) in 677 aa overlap (73-749:10-686) 50 60 70 80 90 100 pF1KF0 DEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLP .::::::::::::::::::::::::::::: XP_011 MSLVSVCTRKRLRWQAHLEFTHNHDVGDLTWDKIAVSLP 10 20 30 110 120 130 140 150 160 pF1KF0 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKD 40 50 60 70 80 90 170 180 190 200 210 220 pF1KF0 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFW 100 110 120 130 140 150 230 240 250 260 270 280 pF1KF0 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFL 160 170 180 190 200 210 290 300 310 320 330 340 pF1KF0 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPS 220 230 240 250 260 270 350 360 370 380 390 400 pF1KF0 QMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQ 280 290 300 310 320 330 410 420 430 440 450 460 pF1KF0 RRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDY 340 350 360 370 380 390 470 480 490 500 510 520 pF1KF0 SMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGEL 400 410 420 430 440 450 530 540 550 560 570 580 pF1KF0 NGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLL 460 470 480 490 500 510 590 600 610 620 630 640 pF1KF0 GGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVT 520 530 540 550 560 570 650 660 670 680 690 700 pF1KF0 HDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCE 580 590 600 610 620 630 710 720 730 740 pF1KF0 LRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG 640 650 660 670 680 >>XP_005261630 (OMIM: 610440) PREDICTED: small G protein (756 aa) initn: 4420 init1: 4393 opt: 4398 Z-score: 2880.3 bits: 543.6 E(85289): 1.1e-153 Smith-Waterman score: 4791; 97.7% identity (97.7% similar) in 741 aa overlap (1-724:1-741) 10 20 30 40 50 60 pF1KF0 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 LLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 PQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 VPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 LLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 FFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 LTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 LKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 HRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDER 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 SKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 ERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICV 610 620 630 640 650 660 670 680 690 700 pF1KF0 GLN-----------------EQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCEL ::: :::::::::::::::::::::::::::::::::::::::: XP_005 GLNQKGLELPLLPTPGHVPSEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCEL 670 680 690 700 710 720 710 720 730 740 pF1KF0 RVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG ::::::::::::::::::::: XP_005 RVLCCFAFSLSQDWELPAKRELGLQSCIQVQGSALP 730 740 750 >>XP_005261629 (OMIM: 610440) PREDICTED: small G protein (766 aa) initn: 4420 init1: 4393 opt: 4398 Z-score: 2880.2 bits: 543.6 E(85289): 1.1e-153 Smith-Waterman score: 4970; 97.8% identity (97.8% similar) in 766 aa overlap (1-749:1-766) 10 20 30 40 50 60 pF1KF0 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KF0 LLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KF0 PQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KF0 VPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KF0 LLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KF0 FFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KF0 LTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KF0 LKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KF0 HRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDER 490 500 510 520 530 540 550 560 570 580 590 600 pF1KF0 SKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREV 550 560 570 580 590 600 610 620 630 640 650 660 pF1KF0 ERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICV 610 620 630 640 650 660 670 680 690 700 pF1KF0 GLN-----------------EQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCEL ::: :::::::::::::::::::::::::::::::::::::::: XP_005 GLNQKGLELPLLPTPGHVPSEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCEL 670 680 690 700 710 720 710 720 730 740 pF1KF0 RVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG :::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG 730 740 750 760 >>XP_016884266 (OMIM: 610440) PREDICTED: small G protein (672 aa) initn: 4373 init1: 4373 opt: 4373 Z-score: 2864.6 bits: 540.6 E(85289): 8.1e-153 Smith-Waterman score: 4373; 100.0% identity (100.0% similar) in 657 aa overlap (68-724:1-657) 40 50 60 70 80 90 pF1KF0 PEFYYDEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKI :::::::::::::::::::::::::::::: XP_016 MEDAPQRLRWQAHLEFTHNHDVGDLTWDKI 10 20 30 100 110 120 130 140 150 pF1KF0 AVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAK 40 50 60 70 80 90 160 170 180 190 200 210 pF1KF0 QIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEE 100 110 120 130 140 150 220 230 240 250 260 270 pF1KF0 EDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLIT 160 170 180 190 200 210 280 290 300 310 320 330 pF1KF0 LHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KF0 SDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVV 280 290 300 310 320 330 400 410 420 430 440 450 pF1KF0 RRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVE 340 350 360 370 380 390 460 470 480 490 500 510 pF1KF0 LTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHC 400 410 420 430 440 450 520 530 540 550 560 570 pF1KF0 WVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLK 460 470 480 490 500 510 580 590 600 610 620 630 pF1KF0 KPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQ 520 530 540 550 560 570 640 650 660 670 680 690 pF1KF0 SVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWV 580 590 600 610 620 630 700 710 720 730 740 pF1KF0 QIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG ::::::::::::::::::::::::::: XP_016 QIKCELRVLCCFAFSLSQDWELPAKRELGLQSCIQVQGSALP 640 650 660 670 >>XP_005261632 (OMIM: 610440) PREDICTED: small G protein (699 aa) initn: 3958 init1: 3931 opt: 3936 Z-score: 2580.5 bits: 488.1 E(85289): 5.3e-137 Smith-Waterman score: 4508; 97.6% identity (97.6% similar) in 699 aa overlap (68-749:1-699) 40 50 60 70 80 90 pF1KF0 PEFYYDEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKI :::::::::::::::::::::::::::::: XP_005 MEDAPQRLRWQAHLEFTHNHDVGDLTWDKI 10 20 30 100 110 120 130 140 150 pF1KF0 AVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAK 40 50 60 70 80 90 160 170 180 190 200 210 pF1KF0 QIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEE 100 110 120 130 140 150 220 230 240 250 260 270 pF1KF0 EDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLIT 160 170 180 190 200 210 280 290 300 310 320 330 pF1KF0 LHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KF0 SDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVV 280 290 300 310 320 330 400 410 420 430 440 450 pF1KF0 RRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVE 340 350 360 370 380 390 460 470 480 490 500 510 pF1KF0 LTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHC 400 410 420 430 440 450 520 530 540 550 560 570 pF1KF0 WVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLK 460 470 480 490 500 510 580 590 600 610 620 630 pF1KF0 KPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQ 520 530 540 550 560 570 640 650 660 670 680 pF1KF0 SVNVTHDAVHAQMDVKLRSLICVGLN-----------------EQVLHLWLEVLCSSLPT :::::::::::::::::::::::::: ::::::::::::::::: XP_005 SVNVTHDAVHAQMDVKLRSLICVGLNQKGLELPLLPTPGHVPSEQVLHLWLEVLCSSLPT 580 590 600 610 620 630 690 700 710 720 730 740 pF1KF0 VEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKH 640 650 660 670 680 690 pF1KF0 HLFSWDVDG ::::::::: XP_005 HLFSWDVDG >>XP_016884269 (OMIM: 610440) PREDICTED: small G protein (583 aa) initn: 3895 init1: 3895 opt: 3895 Z-score: 2554.8 bits: 483.0 E(85289): 1.5e-135 Smith-Waterman score: 3895; 100.0% identity (100.0% similar) in 583 aa overlap (167-749:1-583) 140 150 160 170 180 190 pF1KF0 SELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYP :::::::::::::::::::::::::::::: XP_016 MPSNACFASMGSIGVPRLRRVLRALAWLYP 10 20 30 200 210 220 230 240 250 pF1KF0 EIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIV 40 50 60 70 80 90 260 270 280 290 300 310 pF1KF0 QYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGM 100 110 120 130 140 150 320 330 340 350 360 370 pF1KF0 LHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAY 160 170 180 190 200 210 380 390 400 410 420 430 pF1KF0 LIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLR 220 230 240 250 260 270 440 450 460 470 480 490 pF1KF0 EAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDD 280 290 300 310 320 330 500 510 520 530 540 550 pF1KF0 DELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGV 340 350 360 370 380 390 560 570 580 590 600 610 pF1KF0 TDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKT 400 410 420 430 440 450 620 630 640 650 660 670 pF1KF0 FRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCS 460 470 480 490 500 510 680 690 700 710 720 730 pF1KF0 SLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDM 520 530 540 550 560 570 740 pF1KF0 LVKHHLFSWDVDG ::::::::::::: XP_016 LVKHHLFSWDVDG 580 749 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:02:32 2016 done: Fri Nov 4 20:02:33 2016 Total Scan time: 11.080 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]