Result of FASTA (omim) for
pF1KE9399
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9399, 2715 aa
1>>>pF1KE9399 2715 - 2715 aa - 2715 aa
Library: /omim/omim.rfq.tfa
62861867 residues in 88438 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.4303+/-0.000484; mu= -27.9883+/- 0.030
mean_var=916.8028+/-188.687, 0's: 0 Z-trim(126.1): 210 B-trim: 116 in 1/62
Lambda= 0.042358
statistics sampled from 52025 (52301) to 52025 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.591), width: 16
Scan time: 23.820
The best scores are: opt bits E(88438)
NP_055542 (OMIM: 606834,617284) histone-lysine N-m (2715) 19290 1196.5 0
XP_016883034 (OMIM: 606834,617284) PREDICTED: hist (2527) 17961 1115.3 0
XP_011525863 (OMIM: 606834,617284) PREDICTED: hist (2527) 17961 1115.3 0
XP_011525864 (OMIM: 606834,617284) PREDICTED: hist (2628) 17936 1113.7 0
XP_016883033 (OMIM: 606834,617284) PREDICTED: hist (2685) 16579 1030.8 0
XP_016883035 (OMIM: 606834,617284) PREDICTED: hist (1703) 12145 759.7 8.3e-218
XP_006718902 (OMIM: 159555,605130) PREDICTED: hist (3133) 1674 120.0 5.5e-25
XP_011541135 (OMIM: 159555,605130) PREDICTED: hist (3166) 1674 120.0 5.5e-25
NP_005924 (OMIM: 159555,605130) histone-lysine N-m (3969) 1674 120.1 6.5e-25
NP_001184033 (OMIM: 159555,605130) histone-lysine (3972) 1674 120.1 6.5e-25
XP_011541133 (OMIM: 159555,605130) PREDICTED: hist (4002) 1674 120.1 6.6e-25
XP_011541132 (OMIM: 159555,605130) PREDICTED: hist (4004) 1674 120.1 6.6e-25
XP_011541131 (OMIM: 159555,605130) PREDICTED: hist (4005) 1674 120.1 6.6e-25
XP_016867979 (OMIM: 606833) PREDICTED: histone-lys (3741) 641 57.0 6.3e-06
XP_016867978 (OMIM: 606833) PREDICTED: histone-lys (3873) 641 57.0 6.5e-06
XP_011514756 (OMIM: 606833) PREDICTED: histone-lys (4678) 641 57.1 7.4e-06
XP_011514755 (OMIM: 606833) PREDICTED: histone-lys (4904) 641 57.1 7.7e-06
NP_733751 (OMIM: 606833) histone-lysine N-methyltr (4911) 641 57.1 7.7e-06
XP_016867977 (OMIM: 606833) PREDICTED: histone-lys (4922) 641 57.1 7.7e-06
XP_006716142 (OMIM: 606833) PREDICTED: histone-lys (4927) 641 57.1 7.7e-06
XP_005250088 (OMIM: 606833) PREDICTED: histone-lys (4928) 641 57.1 7.7e-06
XP_011514754 (OMIM: 606833) PREDICTED: histone-lys (4932) 641 57.1 7.7e-06
XP_016867976 (OMIM: 606833) PREDICTED: histone-lys (4934) 641 57.1 7.7e-06
XP_011514753 (OMIM: 606833) PREDICTED: histone-lys (4943) 641 57.1 7.7e-06
XP_006716141 (OMIM: 606833) PREDICTED: histone-lys (4959) 641 57.1 7.8e-06
XP_016867974 (OMIM: 606833) PREDICTED: histone-lys (4966) 641 57.1 7.8e-06
XP_011514752 (OMIM: 606833) PREDICTED: histone-lys (4967) 641 57.1 7.8e-06
XP_016867973 (OMIM: 606833) PREDICTED: histone-lys (4972) 641 57.1 7.8e-06
XP_006716140 (OMIM: 606833) PREDICTED: histone-lys (4982) 641 57.1 7.8e-06
XP_005250083 (OMIM: 606833) PREDICTED: histone-lys (4982) 641 57.1 7.8e-06
XP_005250084 (OMIM: 606833) PREDICTED: histone-lys (4982) 641 57.1 7.8e-06
XP_016867970 (OMIM: 606833) PREDICTED: histone-lys (4982) 641 57.1 7.8e-06
XP_005250082 (OMIM: 606833) PREDICTED: histone-lys (4983) 641 57.1 7.8e-06
XP_016867969 (OMIM: 606833) PREDICTED: histone-lys (4983) 641 57.1 7.8e-06
XP_016867975 (OMIM: 606833) PREDICTED: histone-lys (4954) 629 56.4 1.3e-05
XP_011514758 (OMIM: 606833) PREDICTED: histone-lys (4963) 629 56.4 1.3e-05
XP_016867971 (OMIM: 606833) PREDICTED: histone-lys (4978) 629 56.4 1.3e-05
XP_016867972 (OMIM: 606833) PREDICTED: histone-lys (4978) 629 56.4 1.3e-05
XP_005250085 (OMIM: 606833) PREDICTED: histone-lys (4979) 629 56.4 1.3e-05
NP_001340274 (OMIM: 611055) histone-lysine N-methy (1966) 612 55.0 1.3e-05
XP_005253915 (OMIM: 611055) PREDICTED: histone-lys (1966) 612 55.0 1.3e-05
XP_006719359 (OMIM: 611055) PREDICTED: histone-lys (1966) 612 55.0 1.3e-05
XP_006719679 (OMIM: 147920,602113) PREDICTED: hist (5536) 624 56.1 1.7e-05
XP_005269219 (OMIM: 147920,602113) PREDICTED: hist (5537) 624 56.1 1.7e-05
NP_003473 (OMIM: 147920,602113) histone-lysine N-m (5537) 624 56.1 1.7e-05
XP_006719677 (OMIM: 147920,602113) PREDICTED: hist (5540) 624 56.1 1.7e-05
NP_055527 (OMIM: 611052) histone-lysine N-methyltr (1707) 550 51.1 0.00017
XP_006721169 (OMIM: 611052) PREDICTED: histone-lys (1707) 550 51.1 0.00017
XP_005255780 (OMIM: 611052) PREDICTED: histone-lys (1707) 550 51.1 0.00017
XP_016879398 (OMIM: 611052) PREDICTED: histone-lys (1707) 550 51.1 0.00017
>>NP_055542 (OMIM: 606834,617284) histone-lysine N-methy (2715 aa)
initn: 19290 init1: 19290 opt: 19290 Z-score: 6388.6 bits: 1196.5 E(88438): 0
Smith-Waterman score: 19290; 100.0% identity (100.0% similar) in 2715 aa overlap (1-2715:1-2715)
10 20 30 40 50 60
pF1KE9 MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 LDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 RSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 RQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 KQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 LDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGP
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE9 PMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE9 GSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE9 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE9 GLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGK
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE9 QLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE9 LESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDP
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE9 SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE9 ENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE9 FCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE9 GTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE9 NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE9 SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE9 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDM
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE9 EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVT
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE9 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE9 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE9 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE9 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE9 VSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE9 GEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE9 DKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMS
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE9 GARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCT
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE9 FDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVY
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KE9 RSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVD
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KE9 ATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNK
2650 2660 2670 2680 2690 2700
2710
pF1KE9 LPCNCGAKRCRRFLN
:::::::::::::::
NP_055 LPCNCGAKRCRRFLN
2710
>>XP_016883034 (OMIM: 606834,617284) PREDICTED: histone- (2527 aa)
initn: 17961 init1: 17961 opt: 17961 Z-score: 5950.1 bits: 1115.3 E(88438): 0
Smith-Waterman score: 17961; 100.0% identity (100.0% similar) in 2527 aa overlap (189-2715:1-2527)
160 170 180 190 200 210
pF1KE9 TPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRR
::::::::::::::::::::::::::::::
XP_016 MVQALTELLRRAQAPQAPRSRACEPSTPRR
10 20 30
220 230 240 250 260 270
pF1KE9 SRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGT
40 50 60 70 80 90
280 290 300 310 320 330
pF1KE9 PRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQD
100 110 120 130 140 150
340 350 360 370 380 390
pF1KE9 VPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEE
160 170 180 190 200 210
400 410 420 430 440 450
pF1KE9 AKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPP
220 230 240 250 260 270
460 470 480 490 500 510
pF1KE9 PVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKST
280 290 300 310 320 330
520 530 540 550 560 570
pF1KE9 TFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPA
340 350 360 370 380 390
580 590 600 610 620 630
pF1KE9 PVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPA
400 410 420 430 440 450
640 650 660 670 680 690
pF1KE9 TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGR
460 470 480 490 500 510
700 710 720 730 740 750
pF1KE9 TNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQP
520 530 540 550 560 570
760 770 780 790 800 810
pF1KE9 QLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASM
580 590 600 610 620 630
820 830 840 850 860 870
pF1KE9 PLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVA
640 650 660 670 680 690
880 890 900 910 920 930
pF1KE9 LGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEP
700 710 720 730 740 750
940 950 960 970 980 990
pF1KE9 TGSGGTLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGSGGTLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQ
760 770 780 790 800 810
1000 1010 1020 1030 1040 1050
pF1KE9 CCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEV
820 830 840 850 860 870
1060 1070 1080 1090 1100 1110
pF1KE9 VAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEP
880 890 900 910 920 930
1120 1130 1140 1150 1160 1170
pF1KE9 EEQSRPRKPTLQPVLQLKARRRLDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQSRPRKPTLQPVLQLKARRRLDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKED
940 950 960 970 980 990
1180 1190 1200 1210 1220 1230
pF1KE9 CDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLP
1000 1010 1020 1030 1040 1050
1240 1250 1260 1270 1280 1290
pF1KE9 QHHDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHHDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICS
1060 1070 1080 1090 1100 1110
1300 1310 1320 1330 1340 1350
pF1KE9 ACVRCKSCGATPGKNWDVEWSGDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACVRCKSCGATPGKNWDVEWSGDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCA
1120 1130 1140 1150 1160 1170
1360 1370 1380 1390 1400 1410
pF1KE9 QCDHWVHAKCEGLSDEDYEILSGLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCDHWVHAKCEGLSDEDYEILSGLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQ
1180 1190 1200 1210 1220 1230
1420 1430 1440 1450 1460 1470
pF1KE9 GLLSSKVVGPLLLCTQCGPDGKQLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLLSSKVVGPLLLCTQCGPDGKQLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRH
1240 1250 1260 1270 1280 1290
1480 1490 1500 1510 1520 1530
pF1KE9 SEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDH
1300 1310 1320 1330 1340 1350
1540 1550 1560 1570 1580 1590
pF1KE9 VYAQWRQQEPETPESGQPPGDPSAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYAQWRQQEPETPESGQPPGDPSAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRL
1360 1370 1380 1390 1400 1410
1600 1610 1620 1630 1640 1650
pF1KE9 LYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSC
1420 1430 1440 1450 1460 1470
1660 1670 1680 1690 1700 1710
pF1KE9 LSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRK
1480 1490 1500 1510 1520 1530
1720 1730 1740 1750 1760 1770
pF1KE9 FLTGLEPDAINVLIGSIRIDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLTGLEPDAINVLIGSIRIDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRC
1540 1550 1560 1570 1580 1590
1780 1790 1800 1810 1820 1830
pF1KE9 RILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPI
1600 1610 1620 1630 1640 1650
1840 1850 1860 1870 1880 1890
pF1KE9 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI
1660 1670 1680 1690 1700 1710
1900 1910 1920 1930 1940 1950
pF1KE9 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL
1720 1730 1740 1750 1760 1770
1960 1970 1980 1990 2000 2010
pF1KE9 APPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG
1780 1790 1800 1810 1820 1830
2020 2030 2040 2050 2060 2070
pF1KE9 GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQP
1840 1850 1860 1870 1880 1890
2080 2090 2100 2110 2120 2130
pF1KE9 RGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPP
1900 1910 1920 1930 1940 1950
2140 2150 2160 2170 2180 2190
pF1KE9 APPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLG
1960 1970 1980 1990 2000 2010
2200 2210 2220 2230 2240 2250
pF1KE9 QVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPP
2020 2030 2040 2050 2060 2070
2260 2270 2280 2290 2300 2310
pF1KE9 PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGS
2080 2090 2100 2110 2120 2130
2320 2330 2340 2350 2360 2370
pF1KE9 GGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLL
2140 2150 2160 2170 2180 2190
2380 2390 2400 2410 2420 2430
pF1KE9 ESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTL
2200 2210 2220 2230 2240 2250
2440 2450 2460 2470 2480 2490
pF1KE9 IEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEG
2260 2270 2280 2290 2300 2310
2500 2510 2520 2530 2540 2550
pF1KE9 QEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSL
2320 2330 2340 2350 2360 2370
2560 2570 2580 2590 2600 2610
pF1KE9 ELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKRE
2380 2390 2400 2410 2420 2430
2620 2630 2640 2650 2660 2670
pF1KE9 KFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALR
2440 2450 2460 2470 2480 2490
2680 2690 2700 2710
pF1KE9 RILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN
:::::::::::::::::::::::::::::::::::::
XP_016 RILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN
2500 2510 2520
>>XP_011525863 (OMIM: 606834,617284) PREDICTED: histone- (2527 aa)
initn: 17961 init1: 17961 opt: 17961 Z-score: 5950.1 bits: 1115.3 E(88438): 0
Smith-Waterman score: 17961; 100.0% identity (100.0% similar) in 2527 aa overlap (189-2715:1-2527)
160 170 180 190 200 210
pF1KE9 TPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRR
::::::::::::::::::::::::::::::
XP_011 MVQALTELLRRAQAPQAPRSRACEPSTPRR
10 20 30
220 230 240 250 260 270
pF1KE9 SRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGT
40 50 60 70 80 90
280 290 300 310 320 330
pF1KE9 PRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQD
100 110 120 130 140 150
340 350 360 370 380 390
pF1KE9 VPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEE
160 170 180 190 200 210
400 410 420 430 440 450
pF1KE9 AKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPP
220 230 240 250 260 270
460 470 480 490 500 510
pF1KE9 PVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKST
280 290 300 310 320 330
520 530 540 550 560 570
pF1KE9 TFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPA
340 350 360 370 380 390
580 590 600 610 620 630
pF1KE9 PVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPA
400 410 420 430 440 450
640 650 660 670 680 690
pF1KE9 TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGR
460 470 480 490 500 510
700 710 720 730 740 750
pF1KE9 TNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQP
520 530 540 550 560 570
760 770 780 790 800 810
pF1KE9 QLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASM
580 590 600 610 620 630
820 830 840 850 860 870
pF1KE9 PLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVA
640 650 660 670 680 690
880 890 900 910 920 930
pF1KE9 LGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEP
700 710 720 730 740 750
940 950 960 970 980 990
pF1KE9 TGSGGTLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGSGGTLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQ
760 770 780 790 800 810
1000 1010 1020 1030 1040 1050
pF1KE9 CCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEV
820 830 840 850 860 870
1060 1070 1080 1090 1100 1110
pF1KE9 VAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEP
880 890 900 910 920 930
1120 1130 1140 1150 1160 1170
pF1KE9 EEQSRPRKPTLQPVLQLKARRRLDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEQSRPRKPTLQPVLQLKARRRLDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKED
940 950 960 970 980 990
1180 1190 1200 1210 1220 1230
pF1KE9 CDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLP
1000 1010 1020 1030 1040 1050
1240 1250 1260 1270 1280 1290
pF1KE9 QHHDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHHDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICS
1060 1070 1080 1090 1100 1110
1300 1310 1320 1330 1340 1350
pF1KE9 ACVRCKSCGATPGKNWDVEWSGDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACVRCKSCGATPGKNWDVEWSGDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCA
1120 1130 1140 1150 1160 1170
1360 1370 1380 1390 1400 1410
pF1KE9 QCDHWVHAKCEGLSDEDYEILSGLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCDHWVHAKCEGLSDEDYEILSGLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQ
1180 1190 1200 1210 1220 1230
1420 1430 1440 1450 1460 1470
pF1KE9 GLLSSKVVGPLLLCTQCGPDGKQLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLSSKVVGPLLLCTQCGPDGKQLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRH
1240 1250 1260 1270 1280 1290
1480 1490 1500 1510 1520 1530
pF1KE9 SEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDH
1300 1310 1320 1330 1340 1350
1540 1550 1560 1570 1580 1590
pF1KE9 VYAQWRQQEPETPESGQPPGDPSAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYAQWRQQEPETPESGQPPGDPSAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRL
1360 1370 1380 1390 1400 1410
1600 1610 1620 1630 1640 1650
pF1KE9 LYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSC
1420 1430 1440 1450 1460 1470
1660 1670 1680 1690 1700 1710
pF1KE9 LSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRK
1480 1490 1500 1510 1520 1530
1720 1730 1740 1750 1760 1770
pF1KE9 FLTGLEPDAINVLIGSIRIDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLTGLEPDAINVLIGSIRIDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRC
1540 1550 1560 1570 1580 1590
1780 1790 1800 1810 1820 1830
pF1KE9 RILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPI
1600 1610 1620 1630 1640 1650
1840 1850 1860 1870 1880 1890
pF1KE9 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI
1660 1670 1680 1690 1700 1710
1900 1910 1920 1930 1940 1950
pF1KE9 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL
1720 1730 1740 1750 1760 1770
1960 1970 1980 1990 2000 2010
pF1KE9 APPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHG
1780 1790 1800 1810 1820 1830
2020 2030 2040 2050 2060 2070
pF1KE9 GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQP
1840 1850 1860 1870 1880 1890
2080 2090 2100 2110 2120 2130
pF1KE9 RGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPP
1900 1910 1920 1930 1940 1950
2140 2150 2160 2170 2180 2190
pF1KE9 APPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLG
1960 1970 1980 1990 2000 2010
2200 2210 2220 2230 2240 2250
pF1KE9 QVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPP
2020 2030 2040 2050 2060 2070
2260 2270 2280 2290 2300 2310
pF1KE9 PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGS
2080 2090 2100 2110 2120 2130
2320 2330 2340 2350 2360 2370
pF1KE9 GGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLL
2140 2150 2160 2170 2180 2190
2380 2390 2400 2410 2420 2430
pF1KE9 ESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTL
2200 2210 2220 2230 2240 2250
2440 2450 2460 2470 2480 2490
pF1KE9 IEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEG
2260 2270 2280 2290 2300 2310
2500 2510 2520 2530 2540 2550
pF1KE9 QEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSL
2320 2330 2340 2350 2360 2370
2560 2570 2580 2590 2600 2610
pF1KE9 ELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKRE
2380 2390 2400 2410 2420 2430
2620 2630 2640 2650 2660 2670
pF1KE9 KFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALR
2440 2450 2460 2470 2480 2490
2680 2690 2700 2710
pF1KE9 RILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN
:::::::::::::::::::::::::::::::::::::
XP_011 RILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN
2500 2510 2520
>>XP_011525864 (OMIM: 606834,617284) PREDICTED: histone- (2628 aa)
initn: 17933 init1: 17933 opt: 17936 Z-score: 5941.6 bits: 1113.7 E(88438): 0
Smith-Waterman score: 17936; 99.8% identity (99.9% similar) in 2524 aa overlap (1-2524:1-2524)
10 20 30 40 50 60
pF1KE9 MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 LDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 RSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 RQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 KQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 LDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGP
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE9 PMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE9 GSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE9 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE9 GLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGK
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE9 QLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE9 LESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDP
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE9 SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE9 ENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE9 FCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE9 GTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE9 NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE9 SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE9 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDM
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE9 EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVT
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE9 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE9 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE9 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE9 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE9 VSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE9 GEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE9 DKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMS
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE9 GARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 GARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRSVF
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE9 FDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVY
..:
XP_011 NSIFLLPLLPPAGSAPLTCSTSWPPSTGCSLRGPPVMRKRMRCSSGQPDVPPAWSCPWPC
2530 2540 2550 2560 2570 2580
>>XP_016883033 (OMIM: 606834,617284) PREDICTED: histone- (2685 aa)
initn: 16559 init1: 16559 opt: 16579 Z-score: 5493.3 bits: 1030.8 E(88438): 0
Smith-Waterman score: 19015; 98.9% identity (98.9% similar) in 2715 aa overlap (1-2715:1-2685)
10 20 30 40 50 60
pF1KE9 MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 LDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 RSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 RQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 KQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 LDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGP
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE9 PMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE9 GSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE9 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE9 GLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGK
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE9 QLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE9 LESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDP
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE9 SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFE
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE9 ENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKV
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE9 FCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE9 GTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE9 NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSF
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE9 SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE9 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDM
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE9 EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVT
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE9 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAG
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE9 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPT
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE9 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE9 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKR
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE9 VSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRP
::::::::::::::::::::::::::::::::::::::::
XP_016 VSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGG--------------------
2290 2300 2310 2320
2350 2360 2370 2380 2390 2400
pF1KE9 GEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----------PLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPD
2330 2340 2350 2360 2370
2410 2420 2430 2440 2450 2460
pF1KE9 DKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMS
2380 2390 2400 2410 2420 2430
2470 2480 2490 2500 2510 2520
pF1KE9 GARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCT
2440 2450 2460 2470 2480 2490
2530 2540 2550 2560 2570 2580
pF1KE9 FDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVY
2500 2510 2520 2530 2540 2550
2590 2600 2610 2620 2630 2640
pF1KE9 RSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVD
2560 2570 2580 2590 2600 2610
2650 2660 2670 2680 2690 2700
pF1KE9 ATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNK
2620 2630 2640 2650 2660 2670
2710
pF1KE9 LPCNCGAKRCRRFLN
:::::::::::::::
XP_016 LPCNCGAKRCRRFLN
2680
>>XP_016883035 (OMIM: 606834,617284) PREDICTED: histone- (1703 aa)
initn: 12145 init1: 12145 opt: 12145 Z-score: 4031.6 bits: 759.7 E(88438): 8.3e-218
Smith-Waterman score: 12145; 100.0% identity (100.0% similar) in 1703 aa overlap (1013-2715:1-1703)
990 1000 1010 1020 1030 1040
pF1KE9 NCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGP
::::::::::::::::::::::::::::::
XP_016 MERLAKKGRTIVKTLLPWDSDESPEASPGP
10 20 30
1050 1060 1070 1080 1090 1100
pF1KE9 PGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPA
40 50 60 70 80 90
1110 1120 1130 1140 1150 1160
pF1KE9 PRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRRLDKDALAPGPFASFPNGWTGKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRRLDKDALAPGPFASFPNGWTGKQ
100 110 120 130 140 150
1170 1180 1190 1200 1210 1220
pF1KE9 KSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCC
160 170 180 190 200 210
1230 1240 1250 1260 1270 1280
pF1KE9 DPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGP
220 230 240 250 260 270
1290 1300 1310 1320 1330 1340
pF1KE9 SYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSGDYSLCPRCTQLYEKGNYCPICT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSGDYSLCPRCTQLYEKGNYCPICT
280 290 300 310 320 330
1350 1360 1370 1380 1390 1400
pF1KE9 RCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILSGLPDSVLYTCGPCAGAAQPRWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILSGLPDSVLYTCGPCAGAAQPRWR
340 350 360 370 380 390
1410 1420 1430 1440 1450 1460
pF1KE9 EALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGKQLHPGPCGLQAVSQRFEDGHYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGKQLHPGPCGLQAVSQRFEDGHYK
400 410 420 430 440 450
1470 1480 1490 1500 1510 1520
pF1KE9 SVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRL
460 470 480 490 500 510
1530 1540 1550 1560 1570 1580
pF1KE9 PNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDPSAAFQGKDPAAFSHLEDPRQCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDPSAAFQGKDPAAFSHLEDPRQCA
520 530 540 550 560 570
1590 1600 1610 1620 1630 1640
pF1KE9 LCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCE
580 590 600 610 620 630
1650 1660 1670 1680 1690 1700
pF1KE9 LCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIVNPDGFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIVNPDGFDV
640 650 660 670 680 690
1710 1720 1730 1740 1750 1760
pF1KE9 LRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSLGTLSDLSDCEGRLFPIGYQCSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSLGTLSDLSDCEGRLFPIGYQCSR
700 710 720 730 740 750
1770 1780 1790 1800 1810 1820
pF1KE9 LYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPL
760 770 780 790 800 810
1830 1840 1850 1860 1870 1880
pF1KE9 DTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSF
820 830 840 850 860 870
1890 1900 1910 1920 1930 1940
pF1KE9 GPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVP
880 890 900 910 920 930
1950 1960 1970 1980 1990 2000
pF1KE9 PPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEP
940 950 960 970 980 990
2010 2020 2030 2040 2050 2060
pF1KE9 FQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLD
1000 1010 1020 1030 1040 1050
2070 2080 2090 2100 2110 2120
pF1KE9 GVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLG
1060 1070 1080 1090 1100 1110
2130 2140 2150 2160 2170 2180
pF1KE9 GPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPE
1120 1130 1140 1150 1160 1170
2190 2200 2210 2220 2230 2240
pF1KE9 PPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGV
1180 1190 1200 1210 1220 1230
2250 2260 2270 2280 2290 2300
pF1KE9 LPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDE
1240 1250 1260 1270 1280 1290
2310 2320 2330 2340 2350 2360
pF1KE9 DGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLP
1300 1310 1320 1330 1340 1350
2370 2380 2390 2400 2410 2420
pF1KE9 EDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSED
1360 1370 1380 1390 1400 1410
2430 2440 2450 2460 2470 2480
pF1KE9 GFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGA
1420 1430 1440 1450 1460 1470
2490 2500 2510 2520 2530 2540
pF1KE9 QRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDE
1480 1490 1500 1510 1520 1530
2550 2560 2570 2580 2590 2600
pF1KE9 EEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVI
1540 1550 1560 1570 1580 1590
2610 2620 2630 2640 2650 2660
pF1KE9 EYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSR
1600 1610 1620 1630 1640 1650
2670 2680 2690 2700 2710
pF1KE9 VIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN
1660 1670 1680 1690 1700
>>XP_006718902 (OMIM: 159555,605130) PREDICTED: histone- (3133 aa)
initn: 3466 init1: 1265 opt: 1674 Z-score: 569.9 bits: 120.0 E(88438): 5.5e-25
Smith-Waterman score: 3391; 32.4% identity (47.6% similar) in 2757 aa overlap (1019-2715:390-3133)
990 1000 1010 1020 1030 1040
pF1KE9 KFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGP-PGPRR
: ..::... ::...: : :.:..
XP_006 WMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVV--DSSQKPTPSAREDPAPKK
360 370 380 390 400 410
1050 1060 1070 1080 1090
pF1KE9 GAGAGGPREEV--------VAHPGPEEQDSLL--QRKSARRCVKQRPSYDIFEDSDDSEP
... ::. : :. :::: ... .:::... :.: :. : . . :
XP_006 SSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQ-VSQ-PALVIPPQPPTTGP
420 430 440 450 460 470
1100 1110 1120 1130 1140 1150
pF1KE9 GGPPAPRRRT--PRENELPLPEP-EEQSRPRKPTLQPVLQLKARRRLDKDALAPGP----
.:. :.... : :: :::. .: . .: . .: . :. : :
XP_006 PRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQK---PKEKEKPPPVNKQ
480 490 500 510 520 530
1160 1170 1180 1190 1200
pF1KE9 --------FASFPNGWTGKQKSP-DGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPP
.... :: ..::: : :::::.::::::::. :::: ::::..::::: :
XP_006 ENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPR
540 550 560 570 580 590
1210 1220 1230 1240 1250 1260
pF1KE9 MVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRG
.::.::::.: :.:.:::::.::: ::::: :::: .. ..::::::::::::::. ..
XP_006 VVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQA
600 610 620 630 640 650
1270 1280 1290 1300 1310 1320
pF1KE9 SKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGAT-PGKNWDVEWSG
.:.::::..::..::: ::::.:::. :.:.. :::. ::::::::.: :::.::..::
XP_006 TKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSH
660 670 680 690 700 710
1330 1340 1350 1360 1370
pF1KE9 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLS---DEDYE
:.::: :..:. :::.::.: .::.:.:::::::::..::.:::.:::.:: :: ::
XP_006 DFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYE
720 730 740 750 760 770
1380 1390 1400 1410 1420 1430
pF1KE9 ILSGLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQC--
:::.::.:: ::: :. .:: :: :: .:.::: .::.:.... :: :
XP_006 ILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAK
780 790 800 810 820 830
1440 1450 1460
pF1KE9 -------------------GPD-------GKQLHPGPCGLQAVSQRFEDGHYKSVHSFME
::: .:: : :..:......:.: :: : .
XP_006 PPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSD
840 850 860 870 880 890
1470 1480 1490 1500 1510 1520
pF1KE9 DMVGILMR--HSEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPN-GV
:.: :.. .:. :. ..:....:..... .: .: ::... ..:. . : :.
XP_006 DIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGM
900 910 920 930 940 950
1530 1540 1550 1560
pF1KE9 LPNAVLPPSLDHVYAQWRQQE-------------------------PETPESGQPPGDP-
:::::::::::: ::::...: :..: .:: :
XP_006 LPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPI
960 970 980 990 1000 1010
1570 1580 1590 1600 1610
pF1KE9 -SAAFQGKDPAAFSH---LEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSA
:. . .: .. .:: ::::::: ::: ....::::::::::::::::::.:::
XP_006 LSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSA
1020 1030 1040 1050 1060 1070
1620 1630 1640 1650 1660 1670
pF1KE9 EVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQD
::::..:::::::: :: ::.:.:::.: ::::::::::.:: ::.::::.::. :.: :
XP_006 EVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLD
1080 1090 1100 1110 1120 1130
1680 1690 1700 1710 1720 1730
pF1KE9 DKKVFCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIR
::::.::.: ::. : :.: .::.:.:::.::::::...::::.::::. :...:::.
XP_006 DKKVYCQRHRDLIKG-EVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMT
1140 1150 1160 1170 1180 1190
1740 1750 1760 1770 1780 1790
pF1KE9 IDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLE
:: :: :.:::::: .::::::::::.::::.:::.:: : :.:.: :: : ::
XP_006 IDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRP--PVVEPDINS
1200 1210 1220 1230 1240
1800 1810 1820 1830
pF1KE9 AAE--ENQTIVHSPAPSSE--------------PPGGEDPPLDTDV------LVPGAPE-
..: ::.::.:::. .: ::. . :: . .. .:.
XP_006 TVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRI
1250 1260 1270 1280 1290 1300
1840 1850 1860 1870
pF1KE9 ---RHSPIQNLDPPLRP-DSGSAPPPA---------P------RSFSGARIKVPNYSPSR
.:: : .: :: :...: :. : ::... : .. . ::.:
XP_006 RTPSYSPTQR-SPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQR
1310 1320 1330 1340 1350 1360
1880 1890
pF1KE9 RPL--------------GGVS---------------------FGPLPSPGS-------PS
: ..:: .::: : : :
XP_006 SKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSS
1370 1380 1390 1400 1410 1420
1900
pF1KE9 SLTHHIPTVGD-------------------------------------------------
.: . . :::.
XP_006 NLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVA
1430 1440 1450 1460 1470 1480
1910
pF1KE9 -PDFP--AP--------------------P------------------------------
: .: :: :
XP_006 YPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTD
1490 1500 1510 1520 1530 1540
pF1KE9 ----------------------------------------RRSR----------------
::..
XP_006 STQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSK
1550 1560 1570 1580 1590 1600
1920
pF1KE9 --------------------------------RPS---------------PLAPRPPP--
:: : .:. ::
XP_006 SFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQ
1610 1620 1630 1640 1650 1660
1930 1940 1950
pF1KE9 -----SRWASP----------PLK-------------TSP----QLRVPPPTSVVTAL-T
.. .: ::: .:: :.. :: ..: .
XP_006 VEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASEN
1670 1680 1690 1700 1710 1720
1960 1970 1980
pF1KE9 PTSGELAPPGPA------------------------PSPPPPEDLGPDFEDMEVVSGLSA
: .: .: :.: :. : :.. : . . :. .
XP_006 PGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARAR
1730 1740 1750 1760 1770 1780
1990 2000 2010 2020 2030
pF1KE9 ADLDFAAS-LLGTEPFQEEIVA--AGAMGSSHG-----GPGDSSEEESSPTS---RYIHF
... :. . : :.. . :: . ... :...: : :.... :. : .:
XP_006 SNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNF
1790 1800 1810 1820 1830 1840
2040 2050 2060 2070 2080
pF1KE9 PVTVVSAPGLAPSATPGA---------PRIEQLDGVDDGTDSEA-------EAVQQPRGQ
::.:. : :. . :.: :::::::::.:.. .. : :. .
XP_006 TRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRN
1850 1860 1870 1880 1890 1900
2090 2100
pF1KE9 GTP----------PSGPGVVRAGVLGAAGDRARP--------------------------
: : : . . ...: . .:
XP_006 GKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSL
1910 1920 1930 1940 1950 1960
2110 2120
pF1KE9 ----------PED---------------------------LPSEIVDFVLKN------LG
: : :::.:.:::::: ::
XP_006 ESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALG
1970 1980 1990 2000 2010 2020
2130 2140
pF1KE9 -------------GPGDGGAGPRE----------ESLPPAPPLANG--------------
: : : . :: ..:: . :. ..
XP_006 ESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELP
2030 2040 2050 2060 2070 2080
2150 2160
pF1KE9 ---------------SQPSQGLT------------------------ASPA------DPT
. :::. . ..:: :::
XP_006 LELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPT
2090 2100 2110 2120 2130 2140
2170
pF1KE9 RTFAWLP-----------------------------------GAPGVRV-----------
: ..::..:
XP_006 PEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQ
2150 2160 2170 2180 2190 2200
2180 2190 2200 2210
pF1KE9 -----LSLGPAPE----------PP--KPATSKIILVNKLGQ-VFVKMA---GEGEPVP-
. .:.: :: :::: :.:.::. : ..: .. : . .
XP_006 KYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQL
2210 2220 2230 2240 2250 2260
2220 2230 2240 2250
pF1KE9 -PPVKQPP---------LPPT---------ISPTAPTSWTLPPGPLLGVLPVVGVVR---
:.. : : : ..:. ::: .: :. :.::. .
XP_006 TSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHS
2270 2280 2290 2300 2310 2320
2260 2270
pF1KE9 -PA------PP--------------PPPPPLTLV--------LSSGPASP-------PRQ
:: :: ::: : :: ::. :.: : .
XP_006 FPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPIS
2330 2340 2350 2360 2370 2380
2280 2290
pF1KE9 AIRVKRVSTFSGRSPP---APP------------PYK-----------------------
..... . .. : : :: : .
XP_006 RLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPN
2390 2400 2410 2420 2430 2440
2300 2310 2320
pF1KE9 --------------APRLDED--GEA---------SEDTPQ-----VPGLGSGG--FSRV
:: : .. : : :.:: . : ::.:.. .. :
XP_006 IIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVV
2450 2460 2470 2480 2490 2500
2330 2340 2350 2360
pF1KE9 RMKT---PT----VRGVLDLDRP---GEP-----------AGEESPGPLQERSPLLP---
:.: :: : : . : : : : :...: : .:.. ::
XP_006 SMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLG-IQDQPVALPPSS
2510 2520 2530 2540 2550 2560
2370
pF1KE9 --LPEDGPPQVP------------------------------------------------
.:. : :.:
XP_006 GMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKT
2570 2580 2590 2600 2610 2620
2380
pF1KE9 ------------------------DGPPDLLLE------------------SQWHHYSGE
:.: .. :: : ::.
XP_006 GIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQ
2630 2640 2650 2660 2670 2680
2390 2400 2410
pF1KE9 ASSSEEEP----PSPDDKENQAPKRTG-------PHLR----------------------
:.: : :.: :. : : : :::
XP_006 RSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGT
2690 2700 2710 2720 2730 2740
pF1KE9 ------------------------------------------------------------
XP_006 PGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFS
2750 2760 2770 2780 2790 2800
2420 2430 2440
pF1KE9 ---------------------------FEISSEDGFSVEAESLEGAWRTLIEKVQEARGH
:::::.:::.. :::.: ::..: .::::::..
XP_006 SPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSN
2810 2820 2830 2840 2850 2860
2450 2460 2470 2480 2490 2500
pF1KE9 ARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHG
:::..:::.:..: :.::: ::::.:: ::: ::..:..::::.:. :..: :::::::
XP_006 ARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANE-PPLNPHG
2870 2880 2890 2900 2910 2920
2510 2520 2530 2540 2550 2560
pF1KE9 AARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRH
.:::::.::: .:::::::::.:: :: ::::.::::.:.:::::..::: :::::
XP_006 SARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRH
2930 2940 2950 2960 2970 2980
2570 2580 2590 2600 2610 2620
pF1KE9 LKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGC
:::::::::::::: :::::::::::::::::::::.: ::::. ::::::.::.:::::
XP_006 LKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGC
2990 3000 3010 3020 3030 3040
2630 2640 2650 2660 2670 2680
pF1KE9 YMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTY
::::.:: .::::::::::::::::::::::.::::...:::::::::.:.: :::::::
XP_006 YMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTY
3050 3060 3070 3080 3090 3100
2690 2700 2710
pF1KE9 DYKFPIEDASNKLPCNCGAKRCRRFLN
::::::::::::::::::::.::.:::
XP_006 DYKFPIEDASNKLPCNCGAKKCRKFLN
3110 3120 3130
>>XP_011541135 (OMIM: 159555,605130) PREDICTED: histone- (3166 aa)
initn: 3466 init1: 1265 opt: 1674 Z-score: 569.8 bits: 120.0 E(88438): 5.5e-25
Smith-Waterman score: 3391; 32.4% identity (47.6% similar) in 2757 aa overlap (1019-2715:423-3166)
990 1000 1010 1020 1030 1040
pF1KE9 KFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGP-PGPRR
: ..::... ::...: : :.:..
XP_011 WMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVV--DSSQKPTPSAREDPAPKK
400 410 420 430 440 450
1050 1060 1070 1080 1090
pF1KE9 GAGAGGPREEV--------VAHPGPEEQDSLL--QRKSARRCVKQRPSYDIFEDSDDSEP
... ::. : :. :::: ... .:::... :.: :. : . . :
XP_011 SSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQ-VSQ-PALVIPPQPPTTGP
460 470 480 490 500
1100 1110 1120 1130 1140 1150
pF1KE9 GGPPAPRRRT--PRENELPLPEP-EEQSRPRKPTLQPVLQLKARRRLDKDALAPGP----
.:. :.... : :: :::. .: . .: . .: . :. : :
XP_011 PRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQK---PKEKEKPPPVNKQ
510 520 530 540 550 560
1160 1170 1180 1190 1200
pF1KE9 --------FASFPNGWTGKQKSP-DGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPP
.... :: ..::: : :::::.::::::::. :::: ::::..::::: :
XP_011 ENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPR
570 580 590 600 610 620
1210 1220 1230 1240 1250 1260
pF1KE9 MVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRG
.::.::::.: :.:.:::::.::: ::::: :::: .. ..::::::::::::::. ..
XP_011 VVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQA
630 640 650 660 670 680
1270 1280 1290 1300 1310 1320
pF1KE9 SKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGAT-PGKNWDVEWSG
.:.::::..::..::: ::::.:::. :.:.. :::. ::::::::.: :::.::..::
XP_011 TKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSH
690 700 710 720 730 740
1330 1340 1350 1360 1370
pF1KE9 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLS---DEDYE
:.::: :..:. :::.::.: .::.:.:::::::::..::.:::.:::.:: :: ::
XP_011 DFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYE
750 760 770 780 790 800
1380 1390 1400 1410 1420 1430
pF1KE9 ILSGLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQC--
:::.::.:: ::: :. .:: :: :: .:.::: .::.:.... :: :
XP_011 ILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAK
810 820 830 840 850 860
1440 1450 1460
pF1KE9 -------------------GPD-------GKQLHPGPCGLQAVSQRFEDGHYKSVHSFME
::: .:: : :..:......:.: :: : .
XP_011 PPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSD
870 880 890 900 910 920
1470 1480 1490 1500 1510 1520
pF1KE9 DMVGILMR--HSEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPN-GV
:.: :.. .:. :. ..:....:..... .: .: ::... ..:. . : :.
XP_011 DIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGM
930 940 950 960 970 980
1530 1540 1550 1560
pF1KE9 LPNAVLPPSLDHVYAQWRQQE-------------------------PETPESGQPPGDP-
:::::::::::: ::::...: :..: .:: :
XP_011 LPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPI
990 1000 1010 1020 1030 1040
1570 1580 1590 1600 1610
pF1KE9 -SAAFQGKDPAAFSH---LEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSA
:. . .: .. .:: ::::::: ::: ....::::::::::::::::::.:::
XP_011 LSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSA
1050 1060 1070 1080 1090 1100
1620 1630 1640 1650 1660 1670
pF1KE9 EVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQD
::::..:::::::: :: ::.:.:::.: ::::::::::.:: ::.::::.::. :.: :
XP_011 EVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLD
1110 1120 1130 1140 1150 1160
1680 1690 1700 1710 1720 1730
pF1KE9 DKKVFCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIR
::::.::.: ::. : :.: .::.:.:::.::::::...::::.::::. :...:::.
XP_011 DKKVYCQRHRDLIKG-EVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMT
1170 1180 1190 1200 1210 1220
1740 1750 1760 1770 1780 1790
pF1KE9 IDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLE
:: :: :.:::::: .::::::::::.::::.:::.:: : :.:.: :: : ::
XP_011 IDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRP--PVVEPDINS
1230 1240 1250 1260 1270 1280
1800 1810 1820 1830
pF1KE9 AAE--ENQTIVHSPAPSSE--------------PPGGEDPPLDTDV------LVPGAPE-
..: ::.::.:::. .: ::. . :: . .. .:.
XP_011 TVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRI
1290 1300 1310 1320 1330 1340
1840 1850 1860 1870
pF1KE9 ---RHSPIQNLDPPLRP-DSGSAPPPA---------P------RSFSGARIKVPNYSPSR
.:: : .: :: :...: :. : ::... : .. . ::.:
XP_011 RTPSYSPTQR-SPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQR
1350 1360 1370 1380 1390 1400
1880 1890
pF1KE9 RPL--------------GGVS---------------------FGPLPSPGS-------PS
: ..:: .::: : : :
XP_011 SKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSS
1410 1420 1430 1440 1450 1460
1900
pF1KE9 SLTHHIPTVGD-------------------------------------------------
.: . . :::.
XP_011 NLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVA
1470 1480 1490 1500 1510 1520
1910
pF1KE9 -PDFP--AP--------------------P------------------------------
: .: :: :
XP_011 YPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTD
1530 1540 1550 1560 1570 1580
pF1KE9 ----------------------------------------RRSR----------------
::..
XP_011 STQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSK
1590 1600 1610 1620 1630 1640
1920
pF1KE9 --------------------------------RPS---------------PLAPRPPP--
:: : .:. ::
XP_011 SFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQ
1650 1660 1670 1680 1690 1700
1930 1940 1950
pF1KE9 -----SRWASP----------PLK-------------TSP----QLRVPPPTSVVTAL-T
.. .: ::: .:: :.. :: ..: .
XP_011 VEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASEN
1710 1720 1730 1740 1750 1760
1960 1970 1980
pF1KE9 PTSGELAPPGPA------------------------PSPPPPEDLGPDFEDMEVVSGLSA
: .: .: :.: :. : :.. : . . :. .
XP_011 PGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARAR
1770 1780 1790 1800 1810 1820
1990 2000 2010 2020 2030
pF1KE9 ADLDFAAS-LLGTEPFQEEIVA--AGAMGSSHG-----GPGDSSEEESSPTS---RYIHF
... :. . : :.. . :: . ... :...: : :.... :. : .:
XP_011 SNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNF
1830 1840 1850 1860 1870 1880
2040 2050 2060 2070 2080
pF1KE9 PVTVVSAPGLAPSATPGA---------PRIEQLDGVDDGTDSEA-------EAVQQPRGQ
::.:. : :. . :.: :::::::::.:.. .. : :. .
XP_011 TRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRN
1890 1900 1910 1920 1930 1940
2090 2100
pF1KE9 GTP----------PSGPGVVRAGVLGAAGDRARP--------------------------
: : : . . ...: . .:
XP_011 GKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSL
1950 1960 1970 1980 1990 2000
2110 2120
pF1KE9 ----------PED---------------------------LPSEIVDFVLKN------LG
: : :::.:.:::::: ::
XP_011 ESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALG
2010 2020 2030 2040 2050 2060
2130 2140
pF1KE9 -------------GPGDGGAGPRE----------ESLPPAPPLANG--------------
: : : . :: ..:: . :. ..
XP_011 ESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELP
2070 2080 2090 2100 2110 2120
2150 2160
pF1KE9 ---------------SQPSQGLT------------------------ASPA------DPT
. :::. . ..:: :::
XP_011 LELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPT
2130 2140 2150 2160 2170 2180
2170
pF1KE9 RTFAWLP-----------------------------------GAPGVRV-----------
: ..::..:
XP_011 PEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQ
2190 2200 2210 2220 2230 2240
2180 2190 2200 2210
pF1KE9 -----LSLGPAPE----------PP--KPATSKIILVNKLGQ-VFVKMA---GEGEPVP-
. .:.: :: :::: :.:.::. : ..: .. : . .
XP_011 KYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQL
2250 2260 2270 2280 2290 2300
2220 2230 2240 2250
pF1KE9 -PPVKQPP---------LPPT---------ISPTAPTSWTLPPGPLLGVLPVVGVVR---
:.. : : : ..:. ::: .: :. :.::. .
XP_011 TSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHS
2310 2320 2330 2340 2350 2360
2260 2270
pF1KE9 -PA------PP--------------PPPPPLTLV--------LSSGPASP-------PRQ
:: :: ::: : :: ::. :.: : .
XP_011 FPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPIS
2370 2380 2390 2400 2410 2420
2280 2290
pF1KE9 AIRVKRVSTFSGRSPP---APP------------PYK-----------------------
..... . .. : : :: : .
XP_011 RLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPN
2430 2440 2450 2460 2470 2480
2300 2310 2320
pF1KE9 --------------APRLDED--GEA---------SEDTPQ-----VPGLGSGG--FSRV
:: : .. : : :.:: . : ::.:.. .. :
XP_011 IIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVV
2490 2500 2510 2520 2530 2540
2330 2340 2350 2360
pF1KE9 RMKT---PT----VRGVLDLDRP---GEP-----------AGEESPGPLQERSPLLP---
:.: :: : : . : : : : :...: : .:.. ::
XP_011 SMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLG-IQDQPVALPPSS
2550 2560 2570 2580 2590 2600
2370
pF1KE9 --LPEDGPPQVP------------------------------------------------
.:. : :.:
XP_011 GMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKT
2610 2620 2630 2640 2650 2660
2380
pF1KE9 ------------------------DGPPDLLLE------------------SQWHHYSGE
:.: .. :: : ::.
XP_011 GIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQ
2670 2680 2690 2700 2710 2720
2390 2400 2410
pF1KE9 ASSSEEEP----PSPDDKENQAPKRTG-------PHLR----------------------
:.: : :.: :. : : : :::
XP_011 RSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGT
2730 2740 2750 2760 2770 2780
pF1KE9 ------------------------------------------------------------
XP_011 PGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFS
2790 2800 2810 2820 2830 2840
2420 2430 2440
pF1KE9 ---------------------------FEISSEDGFSVEAESLEGAWRTLIEKVQEARGH
:::::.:::.. :::.: ::..: .::::::..
XP_011 SPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSN
2850 2860 2870 2880 2890 2900
2450 2460 2470 2480 2490 2500
pF1KE9 ARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHG
:::..:::.:..: :.::: ::::.:: ::: ::..:..::::.:. :..: :::::::
XP_011 ARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANE-PPLNPHG
2910 2920 2930 2940 2950
2510 2520 2530 2540 2550 2560
pF1KE9 AARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRH
.:::::.::: .:::::::::.:: :: ::::.::::.:.:::::..::: :::::
XP_011 SARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRH
2960 2970 2980 2990 3000 3010
2570 2580 2590 2600 2610 2620
pF1KE9 LKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGC
:::::::::::::: :::::::::::::::::::::.: ::::. ::::::.::.:::::
XP_011 LKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGC
3020 3030 3040 3050 3060 3070
2630 2640 2650 2660 2670 2680
pF1KE9 YMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTY
::::.:: .::::::::::::::::::::::.::::...:::::::::.:.: :::::::
XP_011 YMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTY
3080 3090 3100 3110 3120 3130
2690 2700 2710
pF1KE9 DYKFPIEDASNKLPCNCGAKRCRRFLN
::::::::::::::::::::.::.:::
XP_011 DYKFPIEDASNKLPCNCGAKKCRKFLN
3140 3150 3160
>>NP_005924 (OMIM: 159555,605130) histone-lysine N-methy (3969 aa)
initn: 3463 init1: 1265 opt: 1674 Z-score: 568.5 bits: 120.1 E(88438): 6.5e-25
Smith-Waterman score: 3411; 32.4% identity (47.7% similar) in 2759 aa overlap (1014-2715:1224-3969)
990 1000 1010 1020 1030 1040
pF1KE9 CLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGP-
:. .: ..::... ::...: :
NP_005 CQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVV--DSSQKPTPSARED
1200 1210 1220 1230 1240 1250
1050 1060 1070 1080 1090
pF1KE9 PGPRRGAGAGGPREEV--------VAHPGPEEQDSLL--QRKSARRCVKQRPSYDIFEDS
:.:..... ::. : :. :::: ... .:::... :.: :. : .
NP_005 PAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQ-VSQ-PALVIPPQP
1260 1270 1280 1290 1300
1100 1110 1120 1130 1140
pF1KE9 DDSEPGGPPAPRRRT--PRENELPLPEP-EEQSRPRKPTLQPVLQLKARRRLDKDALAPG
. : .:. :.... : :: :::. .: . .: . .: . :. :
NP_005 PTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQK---PKEKEKPP
1310 1320 1330 1340 1350 1360
1150 1160 1170 1180 1190
pF1KE9 P------------FASFPNGWTGKQKSP-DGVHRVRVDFKEDCDLENVWLMGGLSVLTSV
: .... :: ..::: : :::::.::::::::. :::: ::::..::::
NP_005 PVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSV
1370 1380 1390 1400 1410 1420
1200 1210 1220 1230 1240 1250
pF1KE9 PGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCG
: : .::.::::.: :.:.:::::.::: ::::: :::: .. ..:::::::::::::
NP_005 PITPRVVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCG
1430 1440 1450 1460 1470 1480
1260 1270 1280 1290 1300 1310
pF1KE9 RKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGAT-PGKNWD
:. ...:.::::..::..::: ::::.:::. :.:.. :::. ::::::::.: :::.::
NP_005 RQHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWD
1490 1500 1510 1520 1530 1540
1320 1330 1340 1350 1360 1370
pF1KE9 VEWSGDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDED
..:: :.::: :..:. :::.::.: .::.:.:::::::::..::.:::.:::.::::
NP_005 AQWSHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEM
1550 1560 1570 1580 1590 1600
1380 1390 1400 1410 1420 1430
pF1KE9 YEILSGLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQC
:::::.::.:: ::: :. .:: :: :: .:.::: .::.:.... :: :
NP_005 YEILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQA
1610 1620 1630 1640 1650 1660
1440 1450 1460
pF1KE9 ---------------------GPD-------GKQLHPGPCGLQAVSQRFEDGHYKSVHSF
::: .:: : :..:......:.: :: :
NP_005 AKPPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEF
1670 1680 1690 1700 1710 1720
1470 1480 1490 1500 1510 1520
pF1KE9 MEDMVGILMR--HSEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPN-
.:.: :.. .:. :. ..:....:..... .: .: ::... ..:. . :
NP_005 SDDIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNS
1730 1740 1750 1760 1770 1780
1530 1540 1550
pF1KE9 GVLPNAVLPPSLDHVYAQWRQQE-------------------------PETPESGQPPGD
:.:::::::::::: ::::...: :..: .::
NP_005 GMLPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTP
1790 1800 1810 1820 1830 1840
1560 1570 1580 1590 1600 1610
pF1KE9 P--SAAFQGKDPAAFSH---LEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIW
: :. . .: .. .:: ::::::: ::: ....::::::::::::::::::.:
NP_005 PILSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALW
1850 1860 1870 1880 1890 1900
1620 1630 1640 1650 1660 1670
pF1KE9 SAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIF
::::::..:::::::: :: ::.:.:::.: ::::::::::.:: ::.::::.::. :.:
NP_005 SAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVF
1910 1920 1930 1940 1950 1960
1680 1690 1700 1710 1720 1730
pF1KE9 QDDKKVFCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGS
:::::.::.: ::. : :.: .::.:.:::.::::::...::::.::::. :...:::
NP_005 LDDKKVYCQRHRDLIKG-EVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGS
1970 1980 1990 2000 2010 2020
1740 1750 1760 1770 1780 1790
pF1KE9 IRIDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAH
. :: :: :.:::::: .::::::::::.::::.:::.:: : :.:.: :: : ::
NP_005 MTIDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRP--PVVEPDI
2030 2040 2050 2060 2070 2080
1800 1810 1820 1830
pF1KE9 LEAAE--ENQTIVHSPAPSSE--------------PPGGEDPPLDTDV------LVPGAP
..: ::.::.:::. .: ::. . :: . .. .:
NP_005 NSTVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVP
2090 2100 2110 2120 2130 2140
1840 1850 1860 1870
pF1KE9 E----RHSPIQNLDPPLRP-DSGSAPPPA---------P------RSFSGARIKVPNYSP
. .:: : .: :: :...: :. : ::... : .. . ::
NP_005 RIRTPSYSPTQR-SPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSP
2150 2160 2170 2180 2190 2200
1880 1890
pF1KE9 SRRPL--------------GGVS---------------------FGPLPSPGS-------
.: : ..:: .::: : :
NP_005 QRSKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTST
2210 2220 2230 2240 2250 2260
1900
pF1KE9 PSSLTHHIPTVGD-----------------------------------------------
:.: . . :::.
NP_005 SSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHN
2270 2280 2290 2300 2310 2320
1910
pF1KE9 ---PDFP--AP--------------------P----------------------------
: .: :: :
NP_005 VAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQH
2330 2340 2350 2360 2370 2380
pF1KE9 ------------------------------------------RRSR--------------
::..
NP_005 TDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHS
2390 2400 2410 2420 2430 2440
1920
pF1KE9 ----------------------------------RPS---------------PLAPRPPP
:: : .:. ::
NP_005 SKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPP
2450 2460 2470 2480 2490 2500
1930 1940 1950
pF1KE9 -------SRWASP----------PLK-------------TSP----QLRVPPPTSVVTAL
.. .: ::: .:: :.. :: ..:
NP_005 MQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISAS
2510 2520 2530 2540 2550 2560
1960 1970 1980
pF1KE9 -TPTSGELAPPGPA------------------------PSPPPPEDLGPDFEDMEVVSGL
.: .: .: :.: :. : :.. : . . :.
NP_005 ENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSAR
2570 2580 2590 2600 2610 2620
1990 2000 2010 2020 2030
pF1KE9 SAADLDFAAS-LLGTEPFQEEIVA--AGAMGSSHG-----GPGDSSEEESSPTS---RYI
. ... :. . : :.. . :: . ... :...: : :.... :. :
NP_005 ARSNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYY
2630 2640 2650 2660 2670 2680
2040 2050 2060 2070
pF1KE9 HFPVTVVSAPGLAPSATPGA---------PRIEQLDGVDDGTDSEA-------EAVQQPR
.: ::.:. : :. . :.: :::::::::.:.. .. : :.
NP_005 NFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPK
2690 2700 2710 2720 2730 2740
2080 2090 2100
pF1KE9 GQGTP----------PSGPGVVRAGVLGAAGDRARP------------------------
.: : : . . ...: . .:
NP_005 RNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLS
2750 2760 2770 2780 2790 2800
2110 2120
pF1KE9 ------------PED---------------------------LPSEIVDFVLKN------
: : :::.:.::::::
NP_005 SLESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQA
2810 2820 2830 2840 2850 2860
2130 2140
pF1KE9 LG-------------GPGDGGAGPRE----------ESLPPAPPLANG------------
:: : : : . :: ..:: . :. ..
NP_005 LGESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFE
2870 2880 2890 2900 2910 2920
2150
pF1KE9 -----------------SQPSQGLT------------------------ASPA------D
. :::. . ..:: :
NP_005 LPLELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVD
2930 2940 2950 2960 2970 2980
2160 2170
pF1KE9 PTRTFAWLP-----------------------------------GAPGVRV---------
:: : ..::..:
NP_005 PTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQ
2990 3000 3010 3020 3030 3040
2180 2190 2200 2210
pF1KE9 -------LSLGPAPE----------PP--KPATSKIILVNKLGQ-VFVKMA---GEGEPV
. .:.: :: :::: :.:.::. : ..: .. : . .
NP_005 NQKYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKI
3050 3060 3070 3080 3090 3100
2220 2230 2240 2250
pF1KE9 P--PPVKQPP---------LPPT---------ISPTAPTSWTLPPGPLLGVLPVVGVVR-
:.. : : : ..:. ::: .: :. :.::. .
NP_005 QLTSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHL
3110 3120 3130 3140 3150 3160
2260 2270
pF1KE9 ---PA------PP--------------PPPPPLTLV--------LSSGPASP-------P
:: :: ::: : :: ::. :.: :
NP_005 HSFPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRP
3170 3180 3190 3200 3210 3220
2280 2290
pF1KE9 RQAIRVKRVSTFSGRSPP---APP------------PYK---------------------
. ..... . .. : : :: : .
NP_005 ISRLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTV
3230 3240 3250 3260 3270 3280
2300 2310 2320
pF1KE9 ----------------APRLDED--GEA---------SEDTPQ-----VPGLGSGG--FS
:: : .. : : :.:: . : ::.:.. ..
NP_005 PNIIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLN
3290 3300 3310 3320 3330 3340
2330 2340 2350 2360
pF1KE9 RVRMKT---PT----VRGVLDLDRP---GEP-----------AGEESPGPLQERSPLLP-
: :.: :: : : . : : : : :...: : .:.. ::
NP_005 VVSMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLG-IQDQPVALPP
3350 3360 3370 3380 3390 3400
2370
pF1KE9 ----LPEDGPPQVP----------------------------------------------
.:. : :.:
NP_005 SSGMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLAS
3410 3420 3430 3440 3450 3460
2380
pF1KE9 --------------------------DGPPDLLLE------------------SQWHHYS
:.: .. :: : :
NP_005 KTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSS
3470 3480 3490 3500 3510 3520
2390 2400 2410
pF1KE9 GEASSSEEEP----PSPDDKENQAPKRTG-------PHLR--------------------
:. :.: : :.: :. : : : :::
NP_005 GQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGT
3530 3540 3550 3560 3570 3580
pF1KE9 ------------------------------------------------------------
NP_005 GTPGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESN
3590 3600 3610 3620 3630 3640
2420 2430 2440
pF1KE9 -----------------------------FEISSEDGFSVEAESLEGAWRTLIEKVQEAR
:::::.:::.. :::.: ::..: .::::::
NP_005 FSSPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEAR
3650 3660 3670 3680 3690 3700
2450 2460 2470 2480 2490 2500
pF1KE9 GHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNP
..:::..:::.:..: :.::: ::::.:: ::: ::..:..::::.:. :..: :::::
NP_005 SNARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANE-PPLNP
3710 3720 3730 3740 3750 3760
2510 2520 2530 2540 2550 2560
pF1KE9 HGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRF
::.:::::.::: .:::::::::.:: :: ::::.::::.:.:::::..::: :::
NP_005 HGSARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRF
3770 3780 3790 3800 3810 3820
2570 2580 2590 2600 2610 2620
pF1KE9 RHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGI
:::::::::::::::: :::::::::::::::::::::.: ::::. ::::::.::.:::
NP_005 RHLKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGI
3830 3840 3850 3860 3870 3880
2630 2640 2650 2660 2670 2680
pF1KE9 GCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEEL
::::::.:: .::::::::::::::::::::::.::::...:::::::::.:.: :::::
NP_005 GCYMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEEL
3890 3900 3910 3920 3930 3940
2690 2700 2710
pF1KE9 TYDYKFPIEDASNKLPCNCGAKRCRRFLN
::::::::::::::::::::::.::.:::
NP_005 TYDYKFPIEDASNKLPCNCGAKKCRKFLN
3950 3960
>>NP_001184033 (OMIM: 159555,605130) histone-lysine N-me (3972 aa)
initn: 3500 init1: 1265 opt: 1674 Z-score: 568.5 bits: 120.1 E(88438): 6.5e-25
Smith-Waterman score: 3391; 32.4% identity (47.6% similar) in 2757 aa overlap (1019-2715:1229-3972)
990 1000 1010 1020 1030 1040
pF1KE9 KFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGP-PGPRR
: ..::... ::...: : :.:..
NP_001 WMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVV--DSSQKPTPSAREDPAPKK
1200 1210 1220 1230 1240 1250
1050 1060 1070 1080 1090
pF1KE9 GAGAGGPREEV--------VAHPGPEEQDSLL--QRKSARRCVKQRPSYDIFEDSDDSEP
... ::. : :. :::: ... .:::... :.: :. : . . :
NP_001 SSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQ-VSQ-PALVIPPQPPTTGP
1260 1270 1280 1290 1300 1310
1100 1110 1120 1130 1140 1150
pF1KE9 GGPPAPRRRT--PRENELPLPEP-EEQSRPRKPTLQPVLQLKARRRLDKDALAPGP----
.:. :.... : :: :::. .: . .: . .: . :. : :
NP_001 PRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQK---PKEKEKPPPVNKQ
1320 1330 1340 1350 1360 1370
1160 1170 1180 1190 1200
pF1KE9 --------FASFPNGWTGKQKSP-DGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPP
.... :: ..::: : :::::.::::::::. :::: ::::..::::: :
NP_001 ENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPR
1380 1390 1400 1410 1420 1430
1210 1220 1230 1240 1250 1260
pF1KE9 MVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRG
.::.::::.: :.:.:::::.::: ::::: :::: .. ..::::::::::::::. ..
NP_001 VVCFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQA
1440 1450 1460 1470 1480 1490
1270 1280 1290 1300 1310 1320
pF1KE9 SKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGAT-PGKNWDVEWSG
.:.::::..::..::: ::::.:::. :.:.. :::. ::::::::.: :::.::..::
NP_001 TKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSH
1500 1510 1520 1530 1540 1550
1330 1340 1350 1360 1370
pF1KE9 DYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLS---DEDYE
:.::: :..:. :::.::.: .::.:.:::::::::..::.:::.:::.:: :: ::
NP_001 DFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSGTEDEMYE
1560 1570 1580 1590 1600 1610
1380 1390 1400 1410 1420 1430
pF1KE9 ILSGLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQC--
:::.::.:: ::: :. .:: :: :: .:.::: .::.:.... :: :
NP_001 ILSNLPESVAYTCVNCTERHPAEWRLALEKELQISLKQVLTALLNSRTTSHLLRYRQAAK
1620 1630 1640 1650 1660 1670
1440 1450 1460
pF1KE9 -------------------GPD-------GKQLHPGPCGLQAVSQRFEDGHYKSVHSFME
::: .:: : :..:......:.: :: : .
NP_001 PPDLNPETEESIPSRSSPEGPDPPVLTEVSKQDDQQPLDLEGVKRKMDQGNYTSVLEFSD
1680 1690 1700 1710 1720 1730
1470 1480 1490 1500 1510 1520
pF1KE9 DMVGILMR--HSEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPN-GV
:.: :.. .:. :. ..:....:..... .: .: ::... ..:. . : :.
NP_001 DIVKIIQAAINSDGGQPEIKKANSMVKSFFIRQMERVFPWFSVKKSRFWEPNKVSSNSGM
1740 1750 1760 1770 1780 1790
1530 1540 1550 1560
pF1KE9 LPNAVLPPSLDHVYAQWRQQE-------------------------PETPESGQPPGDP-
:::::::::::: ::::...: :..: .:: :
NP_001 LPNAVLPPSLDHNYAQWQEREENSHTEQPPLMKKIIPAPKPKGPGEPDSPTPLHPPTPPI
1800 1810 1820 1830 1840 1850
1570 1580 1590 1600 1610
pF1KE9 -SAAFQGKDPAAFSH---LEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSA
:. . .: .. .:: ::::::: ::: ....::::::::::::::::::.:::
NP_001 LSTDRSREDSPELNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSA
1860 1870 1880 1890 1900 1910
1620 1630 1640 1650 1660 1670
pF1KE9 EVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQD
::::..:::::::: :: ::.:.:::.: ::::::::::.:: ::.::::.::. :.: :
NP_001 EVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLD
1920 1930 1940 1950 1960 1970
1680 1690 1700 1710 1720 1730
pF1KE9 DKKVFCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIR
::::.::.: ::. : :.: .::.:.:::.::::::...::::.::::. :...:::.
NP_001 DKKVYCQRHRDLIKG-EVVPENGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMT
1980 1990 2000 2010 2020 2030
1740 1750 1760 1770 1780 1790
pF1KE9 IDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLE
:: :: :.:::::: .::::::::::.::::.:::.:: : :.:.: :: : ::
NP_001 IDCLGILNDLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVECRP--PVVEPDINS
2040 2050 2060 2070 2080
1800 1810 1820 1830
pF1KE9 AAE--ENQTIVHSPAPSSE--------------PPGGEDPPLDTDV------LVPGAPE-
..: ::.::.:::. .: ::. . :: . .. .:.
NP_001 TVEHDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRI
2090 2100 2110 2120 2130 2140
1840 1850 1860 1870
pF1KE9 ---RHSPIQNLDPPLRP-DSGSAPPPA---------P------RSFSGARIKVPNYSPSR
.:: : .: :: :...: :. : ::... : .. . ::.:
NP_001 RTPSYSPTQR-SPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQR
2150 2160 2170 2180 2190 2200
1880 1890
pF1KE9 RPL--------------GGVS---------------------FGPLPSPGS-------PS
: ..:: .::: : : :
NP_001 SKLRIMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLGPLNSSTSLGQNTSTSS
2210 2220 2230 2240 2250 2260
1900
pF1KE9 SLTHHIPTVGD-------------------------------------------------
.: . . :::.
NP_001 NLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVA
2270 2280 2290 2300 2310 2320
1910
pF1KE9 -PDFP--AP--------------------P------------------------------
: .: :: :
NP_001 YPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTD
2330 2340 2350 2360 2370 2380
pF1KE9 ----------------------------------------RRSR----------------
::..
NP_001 STQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSK
2390 2400 2410 2420 2430 2440
1920
pF1KE9 --------------------------------RPS---------------PLAPRPPP--
:: : .:. ::
NP_001 SFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQ
2450 2460 2470 2480 2490 2500
1930 1940 1950
pF1KE9 -----SRWASP----------PLK-------------TSP----QLRVPPPTSVVTAL-T
.. .: ::: .:: :.. :: ..: .
NP_001 VEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASEN
2510 2520 2530 2540 2550 2560
1960 1970 1980
pF1KE9 PTSGELAPPGPA------------------------PSPPPPEDLGPDFEDMEVVSGLSA
: .: .: :.: :. : :.. : . . :. .
NP_001 PGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARAR
2570 2580 2590 2600 2610 2620
1990 2000 2010 2020 2030
pF1KE9 ADLDFAAS-LLGTEPFQEEIVA--AGAMGSSHG-----GPGDSSEEESSPTS---RYIHF
... :. . : :.. . :: . ... :...: : :.... :. : .:
NP_001 SNMFFGLTPLYGVRSYGEEDIPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNF
2630 2640 2650 2660 2670 2680
2040 2050 2060 2070 2080
pF1KE9 PVTVVSAPGLAPSATPGA---------PRIEQLDGVDDGTDSEA-------EAVQQPRGQ
::.:. : :. . :.: :::::::::.:.. .. : :. .
NP_001 TRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRN
2690 2700 2710 2720 2730 2740
2090 2100
pF1KE9 GTP----------PSGPGVVRAGVLGAAGDRARP--------------------------
: : : . . ...: . .:
NP_001 GKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSL
2750 2760 2770 2780 2790 2800
2110 2120
pF1KE9 ----------PED---------------------------LPSEIVDFVLKN------LG
: : :::.:.:::::: ::
NP_001 ESSRRVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALG
2810 2820 2830 2840 2850 2860
2130 2140
pF1KE9 -------------GPGDGGAGPRE----------ESLPPAPPLANG--------------
: : : . :: ..:: . :. ..
NP_001 ESPESSSSELLNLGEGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELP
2870 2880 2890 2900 2910 2920
2150 2160
pF1KE9 ---------------SQPSQGLT------------------------ASPA------DPT
. :::. . ..:: :::
NP_001 LELPSDLSVLTTRSPTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPT
2930 2940 2950 2960 2970 2980
2170
pF1KE9 RTFAWLP-----------------------------------GAPGVRV-----------
: ..::..:
NP_001 PEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQ
2990 3000 3010 3020 3030 3040
2180 2190 2200 2210
pF1KE9 -----LSLGPAPE----------PP--KPATSKIILVNKLGQ-VFVKMA---GEGEPVP-
. .:.: :: :::: :.:.::. : ..: .. : . .
NP_001 KYVPNSTDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQL
3050 3060 3070 3080 3090 3100
2220 2230 2240 2250
pF1KE9 -PPVKQPP---------LPPT---------ISPTAPTSWTLPPGPLLGVLPVVGVVR---
:.. : : : ..:. ::: .: :. :.::. .
NP_001 TSSVSSTPSVMETNTSVLGPMGGGLTLTTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHS
3110 3120 3130 3140 3150 3160
2260 2270
pF1KE9 -PA------PP--------------PPPPPLTLV--------LSSGPASP-------PRQ
:: :: ::: : :: ::. :.: : .
NP_001 FPAATQSSFPPNISNPPSGLLIGVQPPPDPQLLVSESSQRTDLSTTVATPSSGLKKRPIS
3170 3180 3190 3200 3210 3220
2280 2290
pF1KE9 AIRVKRVSTFSGRSPP---APP------------PYK-----------------------
..... . .. : : :: : .
NP_001 RLQTRKNKKLAPSSTPSNIAPSDVVSNMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPN
3230 3240 3250 3260 3270 3280
2300 2310 2320
pF1KE9 --------------APRLDED--GEA---------SEDTPQ-----VPGLGSGG--FSRV
:: : .. : : :.:: . : ::.:.. .. :
NP_001 IIKRSKSSIMYFEPAPLLPQSVGGTAATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVV
3290 3300 3310 3320 3330 3340
2330 2340 2350 2360
pF1KE9 RMKT---PT----VRGVLDLDRP---GEP-----------AGEESPGPLQERSPLLP---
:.: :: : : . : : : : :...: : .:.. ::
NP_001 SMQTTTTPTSSASVPGHVTLTNPRLLGTPDIGSISNLLIKASQQSLG-IQDQPVALPPSS
3350 3360 3370 3380 3390 3400
2370
pF1KE9 --LPEDGPPQVP------------------------------------------------
.:. : :.:
NP_001 GMFPQLGTSQTPSTAAITAASSICVLPSTQTTGITAASPSGEADEHYQLQHVNQLLASKT
3410 3420 3430 3440 3450 3460
2380
pF1KE9 ------------------------DGPPDLLLE------------------SQWHHYSGE
:.: .. :: : ::.
NP_001 GIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQ
3470 3480 3490 3500 3510 3520
2390 2400 2410
pF1KE9 ASSSEEEP----PSPDDKENQAPKRTG-------PHLR----------------------
:.: : :.: :. : : : :::
NP_001 RSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPDQETTSLTSGTGT
3530 3540 3550 3560 3570 3580
pF1KE9 ------------------------------------------------------------
NP_001 PGAEAEQQDTASVEQSSQKECGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFS
3590 3600 3610 3620 3630 3640
2420 2430 2440
pF1KE9 ---------------------------FEISSEDGFSVEAESLEGAWRTLIEKVQEARGH
:::::.:::.. :::.: ::..: .::::::..
NP_001 SPLMLWLQQEQKRKESITEKKPKKGLVFEISSDDGFQICAESIEDAWKSLTDKVQEARSN
3650 3660 3670 3680 3690 3700
2450 2460 2470 2480 2490 2500
pF1KE9 ARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHG
:::..:::.:..: :.::: ::::.:: ::: ::..:..::::.:. :..: :::::::
NP_001 ARLKQLSFAGVNGLRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANE-PPLNPHG
3710 3720 3730 3740 3750 3760
2510 2520 2530 2540 2550 2560
pF1KE9 AARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRH
.:::::.::: .:::::::::.:: :: ::::.::::.:.:::::..::: :::::
NP_001 SARAEVHLRKSAFDMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRH
3770 3780 3790 3800 3810 3820
2570 2580 2590 2600 2610 2620
pF1KE9 LKKTSKEAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGC
:::::::::::::: :::::::::::::::::::::.: ::::. ::::::.::.:::::
NP_001 LKKTSKEAVGVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGC
3830 3840 3850 3860 3870 3880
2630 2640 2650 2660 2670 2680
pF1KE9 YMFRMDDFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTY
::::.:: .::::::::::::::::::::::.::::...:::::::::.:.: :::::::
NP_001 YMFRIDDSEVVDATMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTY
3890 3900 3910 3920 3930 3940
2690 2700 2710
pF1KE9 DYKFPIEDASNKLPCNCGAKRCRRFLN
::::::::::::::::::::.::.:::
NP_001 DYKFPIEDASNKLPCNCGAKKCRKFLN
3950 3960 3970
2715 residues in 1 query sequences
62861867 residues in 88438 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Aug 18 10:16:11 2017 done: Fri Aug 18 10:16:15 2017
Total Scan time: 23.820 Total Display time: 2.520
Function used was FASTA [36.3.4 Apr, 2011]