Result of FASTA (omim) for
pF1KE9279
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9279, 290 aa
1>>>pF1KE9279 290 - 290 aa - 290 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9181+/-0.000439; mu= 16.9071+/- 0.027
mean_var=59.2480+/-11.715, 0's: 0 Z-trim(110.8): 28 B-trim: 340 in 1/48
Lambda= 0.166624
statistics sampled from 19236 (19256) to 19236 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.226), width: 16
Scan time: 5.780
The best scores are: opt bits E(85289)
NP_001669 (OMIM: 182331) sodium/potassium-transpor ( 290) 2000 489.3 3.5e-138
NP_001290192 (OMIM: 182331) sodium/potassium-trans ( 208) 1429 352.0 5.6e-97
NP_000696 (OMIM: 137217) potassium-transporting AT ( 291) 785 197.3 3e-50
NP_001670 (OMIM: 601867) sodium/potassium-transpor ( 279) 597 152.1 1.1e-36
NP_001668 (OMIM: 145500,182330) sodium/potassium-t ( 303) 512 131.7 1.7e-30
>>NP_001669 (OMIM: 182331) sodium/potassium-transporting (290 aa)
initn: 2000 init1: 2000 opt: 2000 Z-score: 2601.7 bits: 489.3 E(85289): 3.5e-138
Smith-Waterman score: 2000; 100.0% identity (100.0% similar) in 290 aa overlap (1-290:1-290)
10 20 30 40 50 60
pF1KE9 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 VMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYNDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 IQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCVFI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 KMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVNYT
190 200 210 220 230 240
250 260 270 280 290
pF1KE9 QPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT
250 260 270 280 290
>>NP_001290192 (OMIM: 182331) sodium/potassium-transport (208 aa)
initn: 1429 init1: 1429 opt: 1429 Z-score: 1862.0 bits: 352.0 E(85289): 5.6e-97
Smith-Waterman score: 1429; 100.0% identity (100.0% similar) in 208 aa overlap (83-290:1-208)
60 70 80 90 100 110
pF1KE9 AMFTLTMWVMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNK
::::::::::::::::::::::::::::::
NP_001 MIRPKTENLDVIVNVSDTESWDQHVQKLNK
10 20 30
120 130 140 150 160 170
pF1KE9 FLEPYNDSIQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLEPYNDSIQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYS
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE9 TGQPCVFIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGQPCVFIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYG
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE9 KKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT
160 170 180 190 200
>>NP_000696 (OMIM: 137217) potassium-transporting ATPase (291 aa)
initn: 704 init1: 314 opt: 785 Z-score: 1023.2 bits: 197.3 E(85289): 3e-50
Smith-Waterman score: 785; 39.5% identity (72.6% similar) in 296 aa overlap (1-289:1-291)
10 20 30 40 50 60
pF1KE9 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW
:. .:::.::: .::.... ::: : :..::: . :..: :.:..:: .:..:.: ..
NP_000 MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLY
10 20 30 40 50 60
70 80 90 100 110
pF1KE9 VMLQTVSDHTPKYQDRLATPGLMIRPKT---ENLDVIVNVSDTESWDQHVQKLNKFLEPY
:..:::. .:: :::.: .::. .:: . ..:... ::::...: . .: :. :: :
NP_000 VLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 NDSIQAQKNDV-CRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQP
: ::.... : .:. : . . :. : .:.:. .: ::::..: ..:. :.:
NP_000 --SPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADP-NFGFEEGKP
130 140 150 160 170
180 190 200 210 220 230
pF1KE9 CVFIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVM---FPANGNIDLMYFPYYGK
: .:::::...: . ... : :: :. : ::. .. .: ::...: :::::::
NP_000 CFIIKMNRIVKFLPSNGSAPRVDCAFL-DQPRE-LGQPLQVKYYPPNGTFSLHYFPYYGK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE9 KFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRVAFKLRINKT
: . .:..::::.:.::. :.:: . :.. : ... .. .: . :.: :::.:.:
NP_000 KAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYEGKVEFKLKIEK
240 250 260 270 280 290
>>NP_001670 (OMIM: 601867) sodium/potassium-transporting (279 aa)
initn: 817 init1: 385 opt: 597 Z-score: 779.3 bits: 152.1 E(85289): 1.1e-36
Smith-Waterman score: 863; 47.6% identity (73.6% similar) in 288 aa overlap (4-285:3-275)
10 20 30 40 50 60
pF1KE9 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW
..:::: .: . ::: :..:: : .:.:::. ::..::::::::::::.:.:..:::
NP_001 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMW
10 20 30 40 50
70 80 90 100 110
pF1KE9 VMLQTVSDHTPKYQDRLATPGLMIRPK-TENLDVIVNVSDTESWDQHVQKLNKFLEPYND
:::::..:..:::.:.. .::::. :: . :. . :: :. ... :.:::.::
NP_001 VMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPY--
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 SIQAQKN-DVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCV
... ::: :: : .:: .: . :::: . : :::..: .::: :.::.
NP_001 TLEEQKNLTVCPDGALFEQ--KGPVYV---ACQFPISLLQACSGMNDPD-FGYSQGNPCI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE9 FIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVN
..::::.:.. . .. :..: :.. : ...: :: ::: ::::::::.::.
NP_001 LVKMNRIIGLKPEGVPRID--CVSKN----EDIPNVAVYPHNGMIDLKYFPYYGKKLHVG
180 190 200 210 220
240 250 260 270 280 290
pF1KE9 YTQPLVAVKFLNVTPNV---EVNVECRIN-AANIATDDERDKFAGRVAFKLRINKT
: ::::::. .. .:: ::.:::.:. .::. ..:.:::: ::: ::.
NP_001 YLQPLVAVQ-VSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA
230 240 250 260 270
>>NP_001668 (OMIM: 145500,182330) sodium/potassium-trans (303 aa)
initn: 661 init1: 347 opt: 512 Z-score: 668.3 bits: 131.7 E(85289): 1.7e-30
Smith-Waterman score: 729; 39.9% identity (67.0% similar) in 303 aa overlap (11-287:4-301)
10 20 30 40 50
pF1KE9 MVIQKEKKSCGQVVEE--WKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLT
:.. :: ::.:.:: . ..:.:::: :: :::::..::: :...: :
NP_001 MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGT
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 MWVMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTESWDQHVQKLNKFLEPYN
. ::: :.:. : ::::.: ::: :. .. .. .: .:.. .: .. .::: :.
NP_001 IQVMLLTISEFKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 DSIQAQKNDV----CR--PGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYS
:: ::..:. : :.. :. : . ...:.:. ::::::..: : :::.
NP_001 DS--AQRDDMIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDET-YGYK
120 130 140 150 160 170
180 190 200 210
pF1KE9 TGQPCVFIKMNRVINFYAGA--NQSMN-------------VTCAGKRDEDAENLGNFVMF
:.::..::.:::..: :.:.. : :.:::::: ...:: .:
NP_001 EGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGNVEYF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE9 PANGN---IDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDER
:: . :.:.::::: .. .: :::.::.: :.: ..:. .::. . ::. . :.
NP_001 GL-GNSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYS-EK
240 250 260 270 280
280 290
pF1KE9 DKFAGRVAFKLRINKT
:.: :: :...
NP_001 DRFQGRFDVKIEVKS
290 300
290 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:06:21 2016 done: Thu Nov 3 12:06:22 2016
Total Scan time: 5.780 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]