Result of FASTA (omim) for
pF1KE8021
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE8021, 741 aa
1>>>pF1KE8021 741 - 741 aa - 741 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0636+/-0.000361; mu= 12.4760+/- 0.022
mean_var=152.5110+/-30.094, 0's: 0 Z-trim(118.2): 32 B-trim: 58 in 1/56
Lambda= 0.103854
statistics sampled from 30861 (30893) to 30861 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.362), width: 16
Scan time: 11.620
The best scores are: opt bits E(85289)
NP_002523 (OMIM: 602552) nuclear pore complex prot ( 741) 4988 759.9 8.6e-219
XP_016880183 (OMIM: 602552) PREDICTED: nuclear por ( 610) 4094 625.8 1.6e-178
NP_001307582 (OMIM: 602552) nuclear pore complex p ( 757) 3750 574.4 6e-163
XP_011522195 (OMIM: 602552) PREDICTED: nuclear por ( 626) 2856 440.4 1.1e-122
>>NP_002523 (OMIM: 602552) nuclear pore complex protein (741 aa)
initn: 4988 init1: 4988 opt: 4988 Z-score: 4049.0 bits: 759.9 E(85289): 8.6e-219
Smith-Waterman score: 4988; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:1-741)
10 20 30 40 50 60
pF1KE8 MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE8 VFGLGGELFLWDGEDSSFLVVRLRGPSGGGEEPALSQYQRLLCINPPLFEIYQVLLSPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VFGLGGELFLWDGEDSSFLVVRLRGPSGGGEEPALSQYQRLLCINPPLFEIYQVLLSPTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE8 HHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE8 SEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEESLVLNKGRAYTASLGETAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEESLVLNKGRAYTASLGETAVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE8 FDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYISLLHSPGNIGKLLGPLPMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYISLLHSPGNIGKLLGPLPMH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE8 PAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDHTSEKSWDSRIDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDHTSEKSWDSRIDLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE8 PSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKCPSRYHCTHEAGVHSVGLTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKCPSRYHCTHEAGVHSVGLTW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE8 IHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE8 ICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRVLAETPDSFEKHIRSILQRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRVLAETPDSFEKHIRSILQRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE8 VANPAFLKASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VANPAFLKASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE8 QLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKLLHSFHSELPVLSDSERD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKLLHSFHSELPVLSDSERD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE8 MKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTIILSAYQRKCIQSILKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTIILSAYQRKCIQSILKE
670 680 690 700 710 720
730 740
pF1KE8 EGEHIREMVKQINDIRNHVNF
:::::::::::::::::::::
NP_002 EGEHIREMVKQINDIRNHVNF
730 740
>>XP_016880183 (OMIM: 602552) PREDICTED: nuclear pore co (610 aa)
initn: 4094 init1: 4094 opt: 4094 Z-score: 3326.2 bits: 625.8 E(85289): 1.6e-178
Smith-Waterman score: 4094; 100.0% identity (100.0% similar) in 610 aa overlap (132-741:1-610)
110 120 130 140 150 160
pF1KE8 LCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVA
::::::::::::::::::::::::::::::
XP_016 MVLELPKRWGKNSEFEGGKSTVNCSTTPVA
10 20 30
170 180 190 200 210 220
pF1KE8 ERFFTSSTSLTLKHAAWYPSEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERFFTSSTSLTLKHAAWYPSEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEES
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE8 LVLNKGRAYTASLGETAVAFDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVLNKGRAYTASLGETAVAFDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYI
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE8 SLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEG
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE8 EEEDDHTSEKSWDSRIDLIPSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEDDHTSEKSWDSRIDLIPSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKC
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE8 PSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCR
280 290 300 310 320 330
470 480 490 500 510 520
pF1KE8 QPAPIRGFWIVPDILGPTMICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPAPIRGFWIVPDILGPTMICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRV
340 350 360 370 380 390
530 540 550 560 570 580
pF1KE8 LAETPDSFEKHIRSILQRSVANPAFLKASEKDIAPPPEECLQLLSRATQVFREQYILKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAETPDSFEKHIRSILQRSVANPAFLKASEKDIAPPPEECLQLLSRATQVFREQYILKQD
400 410 420 430 440 450
590 600 610 620 630 640
pF1KE8 LAKEEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKEEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMK
460 470 480 490 500 510
650 660 670 680 690 700
pF1KE8 KLLHSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLLHSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPK
520 530 540 550 560 570
710 720 730 740
pF1KE8 PTIILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF
::::::::::::::::::::::::::::::::::::::::
XP_016 PTIILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF
580 590 600 610
>>NP_001307582 (OMIM: 602552) nuclear pore complex prote (757 aa)
initn: 3729 init1: 3729 opt: 3750 Z-score: 3046.4 bits: 574.4 E(85289): 6e-163
Smith-Waterman score: 4943; 97.8% identity (97.9% similar) in 757 aa overlap (1-741:1-757)
10 20 30 40 50 60
pF1KE8 MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAEGPVGDGELWQTWLPNHVVFLRLREGLKNQSPTEAEKPASSSLPSSPPPQLLTRNV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE8 VFGLGGELFLWDGEDSSFLVVRLRGPSGGGEEPALSQYQRLLCINPPLFEIYQVLLSPTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFGLGGELFLWDGEDSSFLVVRLRGPSGGGEEPALSQYQRLLCINPPLFEIYQVLLSPTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE8 HHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVAERFFTSSTSLTLKHAAWYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE8 SEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEESLVLNKGRAYTASLGETAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEESLVLNKGRAYTASLGETAVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE8 FDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYISLLHSPGNIGKLLGPLPMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYISLLHSPGNIGKLLGPLPMH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE8 PAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDHTSEKSWDSRIDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEGEEEDDHTSEKSWDSRIDLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE8 PSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKCPSRYHCTHEAGVHSVGLTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKCPSRYHCTHEAGVHSVGLTW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE8 IHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE8 ICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRVLAETPDSFEKHIRSILQRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRVLAETPDSFEKHIRSILQRS
490 500 510 520 530 540
550 560 570 580
pF1KE8 VANPAFL----------------KASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAK
::::::: .::::::::::::::::::::::::::::::::::::
NP_001 VANPAFLNCFTQLRKIKVETLFLRASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE8 EEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKLL
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE8 HSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTI
670 680 690 700 710 720
710 720 730 740
pF1KE8 ILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF
:::::::::::::::::::::::::::::::::::::
NP_001 ILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF
730 740 750
>>XP_011522195 (OMIM: 602552) PREDICTED: nuclear pore co (626 aa)
initn: 2835 init1: 2835 opt: 2856 Z-score: 2323.6 bits: 440.4 E(85289): 1.1e-122
Smith-Waterman score: 4049; 97.3% identity (97.4% similar) in 626 aa overlap (132-741:1-626)
110 120 130 140 150 160
pF1KE8 LCINPPLFEIYQVLLSPTQHHVALIGIKGLMVLELPKRWGKNSEFEGGKSTVNCSTTPVA
::::::::::::::::::::::::::::::
XP_011 MVLELPKRWGKNSEFEGGKSTVNCSTTPVA
10 20 30
170 180 190 200 210 220
pF1KE8 ERFFTSSTSLTLKHAAWYPSEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERFFTSSTSLTLKHAAWYPSEILDPHVVLLTSDNVIRIYSLREPQTPTNVIILSEAEEES
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE8 LVLNKGRAYTASLGETAVAFDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVLNKGRAYTASLGETAVAFDFGPLAAVPKTLFGQNGKDEVVAYPLYILYENGETFLTYI
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE8 SLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAVLCLPCVPNILVIATESGMLYHCVVLEG
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE8 EEEDDHTSEKSWDSRIDLIPSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEDDHTSEKSWDSRIDLIPSLYVFECVELELALKLASGEDDPFDSDFSCPVKLHRDPKC
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE8 PSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSRYHCTHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELSTEQKCFVEHILCTKPLPCR
280 290 300 310 320 330
470 480 490 500 510 520
pF1KE8 QPAPIRGFWIVPDILGPTMICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPAPIRGFWIVPDILGPTMICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESPLRV
340 350 360 370 380 390
530 540 550 560
pF1KE8 LAETPDSFEKHIRSILQRSVANPAFL----------------KASEKDIAPPPEECLQLL
:::::::::::::::::::::::::: .:::::::::::::::::
XP_011 LAETPDSFEKHIRSILQRSVANPAFLNCFTQLRKIKVETLFLRASEKDIAPPPEECLQLL
400 410 420 430 440 450
570 580 590 600 610 620
pF1KE8 SRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKKQLEDLSYCREERKSLREMAERLADK
460 470 480 490 500 510
630 640 650 660 670 680
pF1KE8 YEEAKEKQEDIMNRMKKLLHSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEEAKEKQEDIMNRMKKLLHSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMK
520 530 540 550 560 570
690 700 710 720 730 740
pF1KE8 KDYQQQKMEKVLSLPKPTIILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDYQQQKMEKVLSLPKPTIILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF
580 590 600 610 620
741 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:19:34 2016 done: Tue Nov 8 03:19:36 2016
Total Scan time: 11.620 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]