Result of FASTA (omim) for
pF1KE8000
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE8000, 434 aa
1>>>pF1KE8000 434 - 434 aa - 434 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5672+/-0.000384; mu= 16.8623+/- 0.024
mean_var=85.1738+/-16.797, 0's: 0 Z-trim(114.7): 411 B-trim: 36 in 1/54
Lambda= 0.138970
statistics sampled from 24242 (24669) to 24242 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.289), width: 16
Scan time: 9.180
The best scores are: opt bits E(85289)
NP_003880 (OMIM: 603065) nuclear receptor subfamil ( 434) 2959 603.2 4.1e-172
NP_071285 (OMIM: 603065) nuclear receptor subfamil ( 473) 2955 602.5 7.6e-172
NP_148934 (OMIM: 603065) nuclear receptor subfamil ( 397) 1506 311.9 1.9e-84
NP_000367 (OMIM: 166710,277440,601769) vitamin D3 ( 427) 965 203.5 9e-52
XP_006719650 (OMIM: 166710,277440,601769) PREDICTE ( 427) 965 203.5 9e-52
XP_011537022 (OMIM: 166710,277440,601769) PREDICTE ( 427) 965 203.5 9e-52
NP_001017535 (OMIM: 166710,277440,601769) vitamin ( 427) 965 203.5 9e-52
NP_001017536 (OMIM: 166710,277440,601769) vitamin ( 477) 965 203.5 9.8e-52
NP_001070947 (OMIM: 603881) nuclear receptor subfa ( 319) 603 130.8 5e-30
NP_005113 (OMIM: 603881) nuclear receptor subfamil ( 348) 603 130.8 5.4e-30
NP_001070948 (OMIM: 603881) nuclear receptor subfa ( 352) 595 129.2 1.7e-29
XP_005245751 (OMIM: 603881) PREDICTED: nuclear rec ( 424) 595 129.3 1.9e-29
NP_001070940 (OMIM: 603881) nuclear receptor subfa ( 324) 583 126.8 8.2e-29
XP_005245754 (OMIM: 603881) PREDICTED: nuclear rec ( 353) 583 126.8 8.8e-29
NP_001070945 (OMIM: 603881) nuclear receptor subfa ( 306) 505 111.1 4e-24
NP_001070946 (OMIM: 603881) nuclear receptor subfa ( 339) 497 109.5 1.3e-23
NP_001070944 (OMIM: 603881) nuclear receptor subfa ( 311) 485 107.1 6.5e-23
NP_001070937 (OMIM: 603881) nuclear receptor subfa ( 340) 485 107.1 7e-23
XP_016872546 (OMIM: 602423) PREDICTED: oxysterols ( 323) 399 89.9 1e-17
XP_016872545 (OMIM: 602423) PREDICTED: oxysterols ( 332) 399 89.9 1.1e-17
XP_011518108 (OMIM: 602423) PREDICTED: oxysterols ( 342) 399 89.9 1.1e-17
XP_005252770 (OMIM: 602423) PREDICTED: oxysterols ( 387) 399 89.9 1.2e-17
NP_001123573 (OMIM: 602423) oxysterols receptor LX ( 387) 399 89.9 1.2e-17
NP_001123574 (OMIM: 602423) oxysterols receptor LX ( 402) 399 90.0 1.2e-17
XP_016872547 (OMIM: 602423) PREDICTED: oxysterols ( 402) 399 90.0 1.2e-17
XP_005252766 (OMIM: 602423) PREDICTED: oxysterols ( 402) 399 90.0 1.2e-17
XP_006718179 (OMIM: 602423) PREDICTED: oxysterols ( 402) 399 90.0 1.2e-17
XP_005252767 (OMIM: 602423) PREDICTED: oxysterols ( 402) 399 90.0 1.2e-17
XP_006718178 (OMIM: 602423) PREDICTED: oxysterols ( 402) 399 90.0 1.2e-17
XP_006718175 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 90.0 1.3e-17
XP_005252764 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 90.0 1.3e-17
XP_006718176 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 90.0 1.3e-17
XP_005252763 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 90.0 1.3e-17
XP_011518107 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 90.0 1.3e-17
NP_005684 (OMIM: 602423) oxysterols receptor LXR-a ( 447) 399 90.0 1.3e-17
XP_005252762 (OMIM: 602423) PREDICTED: oxysterols ( 447) 399 90.0 1.3e-17
NP_001238864 (OMIM: 602423) oxysterols receptor LX ( 453) 399 90.0 1.4e-17
NP_001238863 (OMIM: 602423) oxysterols receptor LX ( 453) 399 90.0 1.4e-17
NP_009052 (OMIM: 600380) oxysterols receptor LXR-b ( 461) 382 86.6 1.5e-16
NP_001070941 (OMIM: 603881) nuclear receptor subfa ( 315) 371 84.3 5e-16
NP_001070950 (OMIM: 603881) nuclear receptor subfa ( 357) 371 84.3 5.5e-16
XP_005245750 (OMIM: 603881) PREDICTED: nuclear rec ( 429) 371 84.4 6.4e-16
XP_011532355 (OMIM: 145650,188570,190160,274300) P ( 430) 357 81.6 4.5e-15
XP_016862602 (OMIM: 145650,188570,190160,274300) P ( 430) 357 81.6 4.5e-15
XP_016862604 (OMIM: 145650,188570,190160,274300) P ( 430) 357 81.6 4.5e-15
XP_016862603 (OMIM: 145650,188570,190160,274300) P ( 430) 357 81.6 4.5e-15
XP_011532354 (OMIM: 145650,188570,190160,274300) P ( 461) 357 81.6 4.7e-15
NP_000452 (OMIM: 145650,188570,190160,274300) thyr ( 461) 357 81.6 4.7e-15
XP_006713381 (OMIM: 145650,188570,190160,274300) P ( 461) 357 81.6 4.7e-15
NP_001121648 (OMIM: 145650,188570,190160,274300) t ( 461) 357 81.6 4.7e-15
>>NP_003880 (OMIM: 603065) nuclear receptor subfamily 1 (434 aa)
initn: 2959 init1: 2959 opt: 2959 Z-score: 3211.0 bits: 603.2 E(85289): 4.1e-172
Smith-Waterman score: 2959; 100.0% identity (100.0% similar) in 434 aa overlap (1-434:1-434)
10 20 30 40 50 60
pF1KE8 MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE8 CKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE8 RRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE8 GCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE8 PHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE8 CGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE8 VVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPF
370 380 390 400 410 420
430
pF1KE8 ATPLMQELFGITGS
::::::::::::::
NP_003 ATPLMQELFGITGS
430
>>NP_071285 (OMIM: 603065) nuclear receptor subfamily 1 (473 aa)
initn: 2955 init1: 2955 opt: 2955 Z-score: 3206.1 bits: 602.5 E(85289): 7.6e-172
Smith-Waterman score: 2955; 99.8% identity (100.0% similar) in 434 aa overlap (1-434:40-473)
10 20 30
pF1KE8 MEVRPKESWNHADFVHCEDTESVPGKPSVN
.:::::::::::::::::::::::::::::
NP_071 KEGSLRAPAIPLHSAAAELASNHPRGPEANLEVRPKESWNHADFVHCEDTESVPGKPSVN
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE8 ADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKT
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE8 RRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 RRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMM
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE8 IRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 IRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE8 VSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIE
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE8 DQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 DQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYML
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE8 KKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 KKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLF
370 380 390 400 410 420
400 410 420 430
pF1KE8 LKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
::::::::::::::::::::::::::::::::::::::::::::
NP_071 LKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
430 440 450 460 470
>>NP_148934 (OMIM: 603065) nuclear receptor subfamily 1 (397 aa)
initn: 1506 init1: 1506 opt: 1506 Z-score: 1637.1 bits: 311.9 E(85289): 1.9e-84
Smith-Waterman score: 2625; 91.5% identity (91.5% similar) in 434 aa overlap (1-434:1-397)
10 20 30 40 50 60
pF1KE8 MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE8 CKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 CKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE8 RRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 RRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFR-------
130 140 150 160 170
190 200 210 220 230 240
pF1KE8 GCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLL
::::::::::::::::::::::::::::::
NP_148 ------------------------------VSLQLRGEDGSVWNYKPPADSGGKEIFSLL
180 190 200
250 260 270 280 290 300
pF1KE8 PHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 PHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWE
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE8 CGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 CGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHR
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE8 VVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_148 VVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPF
330 340 350 360 370 380
430
pF1KE8 ATPLMQELFGITGS
::::::::::::::
NP_148 ATPLMQELFGITGS
390
>>NP_000367 (OMIM: 166710,277440,601769) vitamin D3 rece (427 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1050.5 bits: 203.5 E(85289): 9e-52
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (38-430:21-423)
10 20 30 40 50 60
pF1KE8 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
NP_000 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
10 20 30 40 50
70 80 90 100 110 120
pF1KE8 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_000 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
60 70 80 90 100
130 140 150 160 170 180
pF1KE8 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
NP_000 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
110 120 130 140 150 160
190 200 210 220 230
pF1KE8 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
NP_000 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE8 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
NP_000 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE8 ECGRLSYC--LED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
NP_000 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE8 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
NP_000 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
350 360 370 380 390 400
420 430
pF1KE8 IHPFA----TPLMQELFGITGS
..: :::. :.::
NP_000 FQPECSMKLTPLVLEVFGNEIS
410 420
>>XP_006719650 (OMIM: 166710,277440,601769) PREDICTED: v (427 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1050.5 bits: 203.5 E(85289): 9e-52
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (38-430:21-423)
10 20 30 40 50 60
pF1KE8 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
XP_006 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
10 20 30 40 50
70 80 90 100 110 120
pF1KE8 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
XP_006 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
60 70 80 90 100
130 140 150 160 170 180
pF1KE8 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
XP_006 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
110 120 130 140 150 160
190 200 210 220 230
pF1KE8 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
XP_006 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE8 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
XP_006 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE8 ECGRLSYC--LED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
XP_006 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE8 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
XP_006 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
350 360 370 380 390 400
420 430
pF1KE8 IHPFA----TPLMQELFGITGS
..: :::. :.::
XP_006 FQPECSMKLTPLVLEVFGNEIS
410 420
>>XP_011537022 (OMIM: 166710,277440,601769) PREDICTED: v (427 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1050.5 bits: 203.5 E(85289): 9e-52
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (38-430:21-423)
10 20 30 40 50 60
pF1KE8 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
XP_011 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
10 20 30 40 50
70 80 90 100 110 120
pF1KE8 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
XP_011 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
60 70 80 90 100
130 140 150 160 170 180
pF1KE8 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
XP_011 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
110 120 130 140 150 160
190 200 210 220 230
pF1KE8 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
XP_011 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE8 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
XP_011 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE8 ECGRLSYC--LED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
XP_011 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE8 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
XP_011 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
350 360 370 380 390 400
420 430
pF1KE8 IHPFA----TPLMQELFGITGS
..: :::. :.::
XP_011 FQPECSMKLTPLVLEVFGNEIS
410 420
>>NP_001017535 (OMIM: 166710,277440,601769) vitamin D3 r (427 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1050.5 bits: 203.5 E(85289): 9e-52
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (38-430:21-423)
10 20 30 40 50 60
pF1KE8 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
NP_001 MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
10 20 30 40 50
70 80 90 100 110 120
pF1KE8 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_001 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
60 70 80 90 100
130 140 150 160 170 180
pF1KE8 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
NP_001 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
110 120 130 140 150 160
190 200 210 220 230
pF1KE8 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
NP_001 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE8 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
NP_001 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE8 ECGRLSYC--LED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
NP_001 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE8 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
NP_001 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
350 360 370 380 390 400
420 430
pF1KE8 IHPFA----TPLMQELFGITGS
..: :::. :.::
NP_001 FQPECSMKLTPLVLEVFGNEIS
410 420
>>NP_001017536 (OMIM: 166710,277440,601769) vitamin D3 r (477 aa)
initn: 969 init1: 297 opt: 965 Z-score: 1049.8 bits: 203.5 E(85289): 9.8e-52
Smith-Waterman score: 1050; 42.2% identity (70.8% similar) in 408 aa overlap (38-430:71-473)
10 20 30 40 50 60
pF1KE8 SWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRR
:.:: ::::.:::.:::.::::::::::::
NP_001 STYLPPAPSGMEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRR
50 60 70 80 90 100
70 80 90 100 110 120
pF1KE8 AMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKR
.:::.: . ::: .: :.::. .::.::::::..:.. :: ::.:..:: :...: .: .
NP_001 SMKRKALFTCPF-NGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILK
110 120 130 140 150
130 140 150 160 170 180
pF1KE8 KKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGC----E
.: :.. . : . :.:::. .: :.::. ::.: :.: : .:: : ...:
NP_001 RKEEEALKDSLRPK-LSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPS
160 170 180 190 200 210
190 200 210 220 230
pF1KE8 LPESLQAPSREEAAKWSQVRKDLC----SLKVSLQLRGEDGSVWNYKPPADSGGKEIFSL
:.: ..:: .. :. .: : .. : .. . : : . :. . .:.
NP_001 RPNSRHTPSF--SGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSM
220 230 240 250 260 270
240 250 260 270 280 290
pF1KE8 LPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTW
:::.::. .: .. .:.:::.: :::: :::: :::..:.:. .:: : :. . .:
NP_001 LPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSW
280 290 300 310 320 330
300 310 320 330 340 350
pF1KE8 ECGRLSYC--LED-TAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGV
:: .: . : : .: . :.::..::. ::::.:::::.::..:: . :::::::
NP_001 TCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGV
340 350 360 370 380 390
360 370 380 390 400 410
pF1KE8 LQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQD
. ... .:.... ::..::.: .: :. ..:. :.. :..:::.: .:... : .
NP_001 QDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQY-RCLS
400 410 420 430 440 450
420 430
pF1KE8 IHPFA----TPLMQELFGITGS
..: :::. :.::
NP_001 FQPECSMKLTPLVLEVFGNEIS
460 470
>>NP_001070947 (OMIM: 603881) nuclear receptor subfamily (319 aa)
initn: 811 init1: 348 opt: 603 Z-score: 660.0 bits: 130.8 E(85289): 5e-30
Smith-Waterman score: 797; 39.3% identity (64.0% similar) in 364 aa overlap (66-428:7-317)
40 50 60 70 80 90
pF1KE8 GGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQ
::..... ::: :.::... ::.:
NP_001 MLPKRSRRTVSKSIGPTCPF-AGSCEVSKTQRRHCP
10 20 30
100 110 120 130 140 150
pF1KE8 ACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELM
::::.:::..::.:.::.: ::. ::: ......: .: :..::. .:: :.
NP_001 ACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLL
40 50 60 70 80
160 170 180 190 200 210
pF1KE8 DAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQL
:. . . : : .: .:: :. : . : ::
NP_001 GAHTRHMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP------------------------
90 100 110 120
220 230 240 250 260 270
pF1KE8 RGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISL
.. :. :.::..:.: .:.:.: . ::.:::::::::
NP_001 --------------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISL
130 140 150 160
280 290 300 310 320 330
pF1KE8 LKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQQLLLEPMLKFHYMLKKLQ
::::: :.:.. .::.: .: .. :: : : .:: : ::: .:: ...:: :.:::
NP_001 LKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQ
170 180 190 200 210 220
340 350 360 370 380 390
pF1KE8 LHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIM
:.: ::::. :..::::::::: :. .:::::..:.::.:::. .. .: :::. :..
NP_001 LQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLL
230 240 250 260 270 280
400 410 420 430
pF1KE8 AMLTELRSINAQHTQRLLRIQDIHPFATPLMQELFGITGS
..:.:::::: . .. .:: . . ::.::.
NP_001 GLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEICS
290 300 310
>>NP_005113 (OMIM: 603881) nuclear receptor subfamily 1 (348 aa)
initn: 986 init1: 348 opt: 603 Z-score: 659.5 bits: 130.8 E(85289): 5.4e-30
Smith-Waterman score: 972; 42.2% identity (66.1% similar) in 389 aa overlap (41-428:11-346)
20 30 40 50 60 70
pF1KE8 HADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATGYHFNVMTCEGCKGFFRRAMK
: ::::.:::::::..:::::::::::...
NP_005 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVS
10 20 30 40
80 90 100 110 120 130
pF1KE8 RNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALIKRKKS
.. ::: :.::... ::.: ::::.:::..::.:.::.: ::. ::: ....
NP_005 KSIGPTCPF-AGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRA
50 60 70 80 90
140 150 160 170 180 190
pF1KE8 ERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELPESLQA
..: .: :..::. .:: :. :. . . : : .: .:: :. : . : :
NP_005 QQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-PLPTLA
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE8 PSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYM
: .. :. :.::..:.:
NP_005 P--------------------------------------------VLPLVTHFADINTFM
160
260 270 280 290 300 310
pF1KE8 FKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLED
.:.:.: . ::.:::::::::::::: :.:.. .::.: .: .. :: : : .::
NP_005 VLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIED
170 180 190 200 210 220
320 330 340 350 360
pF1KE8 TAG-GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQF
: ::: .:: ...:: :.::::.: ::::. :..::::::::: :. .:::::..
NP_005 GARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEM
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE8 AITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQELF
:.::.:::. .. .: :::. :....:.:::::: . .. .:: . . ::.::.
NP_005 ALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEIC
290 300 310 320 330 340
430
pF1KE8 GITGS
NP_005 S
434 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:15:44 2016 done: Sun Nov 6 09:15:45 2016
Total Scan time: 9.180 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]