Result of FASTA (omim) for
pF1KE4045
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE4045, 267 aa
1>>>pF1KE4045 267 - 267 aa - 267 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4093+/-0.000341; mu= 14.2875+/- 0.021
mean_var=73.4322+/-14.990, 0's: 0 Z-trim(114.5): 424 B-trim: 189 in 1/48
Lambda= 0.149669
statistics sampled from 24846 (25293) to 24846 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.276), width: 16
Scan time: 3.420
The best scores are: opt bits E(91774)
NP_001034930 (OMIM: 616310) rho GTPase-activating ( 267) 1784 394.4 1.2e-109
NP_955389 (OMIM: 610589) rho GTPase-activating pro ( 501) 1440 320.3 4.6e-87
NP_055598 (OMIM: 610589) rho GTPase-activating pro (1023) 1440 320.5 8.3e-87
XP_011538317 (OMIM: 610585) rho GTPase-activating ( 359) 291 72.1 1.7e-12
XP_005277572 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 789) 293 72.8 2.4e-12
NP_001287881 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 789) 293 72.8 2.4e-12
XP_005277571 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 790) 293 72.8 2.4e-12
XP_016856330 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 840) 293 72.8 2.5e-12
XP_011507661 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 841) 293 72.8 2.5e-12
XP_016856329 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 931) 293 72.8 2.8e-12
XP_016856327 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 931) 293 72.8 2.8e-12
XP_024301784 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 973) 293 72.8 2.9e-12
XP_011507658 (OMIM: 606524) SLIT-ROBO Rho GTPase-a ( 986) 293 72.8 2.9e-12
XP_016871965 (OMIM: 610585) rho GTPase-activating ( 414) 288 71.5 3e-12
XP_024301783 (OMIM: 606524) SLIT-ROBO Rho GTPase-a (1053) 293 72.8 3e-12
XP_024301782 (OMIM: 606524) SLIT-ROBO Rho GTPase-a (1053) 293 72.8 3e-12
XP_024303868 (OMIM: 610585) rho GTPase-activating ( 420) 288 71.5 3.1e-12
XP_005277568 (OMIM: 606524) SLIT-ROBO Rho GTPase-a (1070) 293 72.9 3.1e-12
NP_001164108 (OMIM: 606524) SLIT-ROBO Rho GTPase-a (1070) 293 72.9 3.1e-12
NP_056141 (OMIM: 606524) SLIT-ROBO Rho GTPase-acti (1071) 293 72.9 3.1e-12
XP_005277567 (OMIM: 606524) SLIT-ROBO Rho GTPase-a (1071) 293 72.9 3.1e-12
XP_011507657 (OMIM: 606524) SLIT-ROBO Rho GTPase-a (1083) 293 72.9 3.1e-12
XP_011507656 (OMIM: 606524) SLIT-ROBO Rho GTPase-a (1084) 293 72.9 3.1e-12
NP_001657 (OMIM: 300023) rho GTPase-activating pro ( 946) 292 72.6 3.2e-12
NP_001158213 (OMIM: 300023) rho GTPase-activating ( 986) 292 72.6 3.3e-12
NP_001242955 (OMIM: 610585) rho GTPase-activating ( 608) 288 71.6 4.1e-12
XP_011538315 (OMIM: 610585) rho GTPase-activating ( 436) 286 71.1 4.2e-12
NP_067049 (OMIM: 610585) rho GTPase-activating pro ( 698) 288 71.7 4.6e-12
NP_001242954 (OMIM: 610585) rho GTPase-activating ( 704) 288 71.7 4.6e-12
NP_001334667 (OMIM: 610585) rho GTPase-activating ( 704) 288 71.7 4.6e-12
XP_011538307 (OMIM: 610585) rho GTPase-activating ( 624) 286 71.2 5.7e-12
XP_005270071 (OMIM: 610585) rho GTPase-activating ( 624) 286 71.2 5.7e-12
NP_001242953 (OMIM: 610585) rho GTPase-activating ( 714) 286 71.2 6.3e-12
XP_011538305 (OMIM: 610585) rho GTPase-activating ( 720) 286 71.2 6.4e-12
XP_024303867 (OMIM: 610585) rho GTPase-activating ( 720) 286 71.2 6.4e-12
XP_011538304 (OMIM: 610585) rho GTPase-activating ( 720) 286 71.2 6.4e-12
NP_001308097 (OMIM: 617716) rho GTPase-activating ( 568) 280 69.9 1.3e-11
NP_001157743 (OMIM: 114500,604258) rho GTPase-acti (1017) 283 70.7 1.3e-11
NP_001335013 (OMIM: 114500,604258) rho GTPase-acti (1017) 283 70.7 1.3e-11
NP_001335011 (OMIM: 114500,604258) rho GTPase-acti (1017) 283 70.7 1.3e-11
NP_001335012 (OMIM: 114500,604258) rho GTPase-acti (1017) 283 70.7 1.3e-11
NP_006085 (OMIM: 114500,604258) rho GTPase-activat (1091) 283 70.7 1.4e-11
NP_001303597 (OMIM: 114500,604258) rho GTPase-acti (1125) 283 70.7 1.4e-11
XP_005256948 (OMIM: 617716) rho GTPase-activating ( 738) 280 69.9 1.6e-11
NP_001308093 (OMIM: 617716) rho GTPase-activating ( 768) 280 70.0 1.6e-11
NP_001308096 (OMIM: 617716) rho GTPase-activating ( 774) 280 70.0 1.7e-11
NP_001334664 (OMIM: 610585) rho GTPase-activating ( 655) 279 69.7 1.7e-11
XP_011538308 (OMIM: 610585) rho GTPase-activating ( 661) 279 69.7 1.7e-11
NP_001308095 (OMIM: 617716) rho GTPase-activating ( 812) 280 70.0 1.7e-11
NP_055674 (OMIM: 617716) rho GTPase-activating pro ( 818) 280 70.0 1.7e-11
>>NP_001034930 (OMIM: 616310) rho GTPase-activating prot (267 aa)
initn: 1784 init1: 1784 opt: 1784 Z-score: 2090.0 bits: 394.4 E(91774): 1.2e-109
Smith-Waterman score: 1784; 100.0% identity (100.0% similar) in 267 aa overlap (1-267:1-267)
10 20 30 40 50 60
pF1KE4 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE4 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVS
190 200 210 220 230 240
250 260
pF1KE4 VLLHHWKALKKVNMKLLVNIREREDNV
:::::::::::::::::::::::::::
NP_001 VLLHHWKALKKVNMKLLVNIREREDNV
250 260
>>NP_955389 (OMIM: 610589) rho GTPase-activating protein (501 aa)
initn: 1439 init1: 1439 opt: 1440 Z-score: 1684.6 bits: 320.3 E(91774): 4.6e-87
Smith-Waterman score: 1440; 95.2% identity (97.0% similar) in 231 aa overlap (1-226:1-231)
10 20 30 40 50 60
pF1KE4 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_955 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_955 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
130 140 150 160 170 180
190 200 210 220 230
pF1KE4 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKK-----GVYQTLSWKRYQPCW
::::::::::::::::::::::::::::::::::::.::: .: :::
NP_955 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
190 200 210 220 230 240
240 250 260
pF1KE4 VLMVSVLLHHWKALKKVNMKLLVNIREREDNV
NP_955 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
250 260 270 280 290 300
>>NP_055598 (OMIM: 610589) rho GTPase-activating protein (1023 aa)
initn: 1439 init1: 1439 opt: 1440 Z-score: 1680.1 bits: 320.5 E(91774): 8.3e-87
Smith-Waterman score: 1440; 95.2% identity (97.0% similar) in 231 aa overlap (1-226:1-231)
10 20 30 40 50 60
pF1KE4 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MWDQRLVRLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHSAVP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE4 EYGHIPSFLVDACTSLEEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_055 EYGHIPSFLVDACTSLEDHIHTEGLFRKSGSVIRLKALKNKVDHGEGCLSSAPPCDIAGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE4 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLADHTVHVLRYFFNFLRN
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_055 LKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVHVLRYFFNFLRN
130 140 150 160 170 180
190 200 210 220 230
pF1KE4 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKK-----GVYQTLSWKRYQPCW
::::::::::::::::::::::::::::::::::::.::: .: :::
NP_055 VSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQTLIDYASDIGR
190 200 210 220 230 240
240 250 260
pF1KE4 VLMVSVLLHHWKALKKVNMKLLVNIREREDNV
NP_055 VPDFILEKIPAMLGIDGLCATPSLEGFEEGEYETPGEYKRKRRQSVGDFVSGALNKFKPN
250 260 270 280 290 300
>>XP_011538317 (OMIM: 610585) rho GTPase-activating prot (359 aa)
initn: 256 init1: 114 opt: 291 Z-score: 345.8 bits: 72.1 E(91774): 1.7e-12
Smith-Waterman score: 291; 32.0% identity (60.6% similar) in 203 aa overlap (28-222:156-357)
10 20 30 40 50
pF1KE4 MWDQRLVKLALLQHLRAFYGIKVKGVRGQCDRRRHETAATEIGGKIFGVPFNALPHS
: :: : . ::: .. :
XP_011 PEALLLMASSQRDMEDWVQAIRRVIWAPLGGGTARRSHAHPLEPLPPGIFGQRLEETVHH
130 140 150 160 170 180
60 70 80 90 100 110
pF1KE4 AVPEYG-HIPSFLVDACTSL--EEHIHTEGLFRKSGSVIRLKALKNKVDHGEGCL--SSA
.:: .. .::. :... :. . ::::: :.. .. :... : :: : :..
XP_011 ER-KYGPRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTT
190 200 210 220 230 240
120 130 140 150 160
pF1KE4 PPCDIAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKAILLLSCLLAD---HTVH
.:.::: ..::::::..: .: .:. :: :...... : :. ... . .
XP_011 DVHTVASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYN
250 260 270 280 290 300
170 180 190 200 210 220
pF1KE4 VLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNAEKKGVYQTLSWK
.:::. .:: .:. :. :::. .:::..:.::.:. . . ::::
XP_011 LLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEESKKGVLT
310 320 330 340 350
230 240 250 260
pF1KE4 RYQPCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV
>>XP_005277572 (OMIM: 606524) SLIT-ROBO Rho GTPase-activ (789 aa)
initn: 280 init1: 147 opt: 293 Z-score: 343.2 bits: 72.8 E(91774): 2.4e-12
Smith-Waterman score: 293; 33.7% identity (65.7% similar) in 169 aa overlap (65-226:503-670)
40 50 60 70 80 90
pF1KE4 HETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTS-LEEH-IHTEGLFRKSGSV
:: ..:..: . .: .. ::.:: :::
XP_005 LQKTLGESQRTDCSLARRSSTVRKQDSSQAIP-LVVESCIRFISRHGLQHEGIFRVSGSQ
480 490 500 510 520 530
100 110 120 130 140
pF1KE4 IRLKALKNKVDHGEGCLSSAP---PCD-IAGLLKQFFRELPEPILPADL-HEALLKAQQL
.... .:: ..:: :.. : :::.:: .:: : .:..: :. :. . . .
XP_005 VEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMD
540 550 560 570 580 590
150 160 170 180 190 200
pF1KE4 GTEEKNKAILLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTS
. .:. : . .: :. ..::.: :: ..: : :: :: :::. :.:.:...
XP_005 NLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVP
600 610 620 630 640 650
210 220 230 240 250 260
pF1KE4 EGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV
:::...: .:. . . .:.
XP_005 EGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVED
660 670 680 690 700 710
>>NP_001287881 (OMIM: 606524) SLIT-ROBO Rho GTPase-activ (789 aa)
initn: 280 init1: 147 opt: 293 Z-score: 343.2 bits: 72.8 E(91774): 2.4e-12
Smith-Waterman score: 293; 33.7% identity (65.7% similar) in 169 aa overlap (65-226:503-670)
40 50 60 70 80 90
pF1KE4 HETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTS-LEEH-IHTEGLFRKSGSV
:: ..:..: . .: .. ::.:: :::
NP_001 LQKTLGESQRTDCSLARRSSTVRKQDSSQAIP-LVVESCIRFISRHGLQHEGIFRVSGSQ
480 490 500 510 520 530
100 110 120 130 140
pF1KE4 IRLKALKNKVDHGEGCLSSAP---PCD-IAGLLKQFFRELPEPILPADL-HEALLKAQQL
.... .:: ..:: :.. : :::.:: .:: : .:..: :. :. . . .
NP_001 VEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMD
540 550 560 570 580 590
150 160 170 180 190 200
pF1KE4 GTEEKNKAILLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTS
. .:. : . .: :. ..::.: :: ..: : :: :: :::. :.:.:...
NP_001 NLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVP
600 610 620 630 640 650
210 220 230 240 250 260
pF1KE4 EGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV
:::...: .:. . . .:.
NP_001 EGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVED
660 670 680 690 700 710
>>XP_005277571 (OMIM: 606524) SLIT-ROBO Rho GTPase-activ (790 aa)
initn: 280 init1: 147 opt: 293 Z-score: 343.2 bits: 72.8 E(91774): 2.4e-12
Smith-Waterman score: 293; 33.7% identity (65.7% similar) in 169 aa overlap (65-226:504-671)
40 50 60 70 80 90
pF1KE4 HETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTS-LEEH-IHTEGLFRKSGSV
:: ..:..: . .: .. ::.:: :::
XP_005 LQKTLGESQRTDCSLARRSSTVRKQDSSQAIP-LVVESCIRFISRHGLQHEGIFRVSGSQ
480 490 500 510 520 530
100 110 120 130 140
pF1KE4 IRLKALKNKVDHGEGCLSSAP---PCD-IAGLLKQFFRELPEPILPADL-HEALLKAQQL
.... .:: ..:: :.. : :::.:: .:: : .:..: :. :. . . .
XP_005 VEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMD
540 550 560 570 580 590
150 160 170 180 190 200
pF1KE4 GTEEKNKAILLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTS
. .:. : . .: :. ..::.: :: ..: : :: :: :::. :.:.:...
XP_005 NLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVP
600 610 620 630 640 650
210 220 230 240 250 260
pF1KE4 EGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV
:::...: .:. . . .:.
XP_005 EGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVED
660 670 680 690 700 710
>>XP_016856330 (OMIM: 606524) SLIT-ROBO Rho GTPase-activ (840 aa)
initn: 280 init1: 147 opt: 293 Z-score: 342.8 bits: 72.8 E(91774): 2.5e-12
Smith-Waterman score: 293; 33.7% identity (65.7% similar) in 169 aa overlap (65-226:503-670)
40 50 60 70 80 90
pF1KE4 HETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTS-LEEH-IHTEGLFRKSGSV
:: ..:..: . .: .. ::.:: :::
XP_016 LQKTLGESQRTDCSLARRSSTVRKQDSSQAIP-LVVESCIRFISRHGLQHEGIFRVSGSQ
480 490 500 510 520 530
100 110 120 130 140
pF1KE4 IRLKALKNKVDHGEGCLSSAP---PCD-IAGLLKQFFRELPEPILPADL-HEALLKAQQL
.... .:: ..:: :.. : :::.:: .:: : .:..: :. :. . . .
XP_016 VEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMD
540 550 560 570 580 590
150 160 170 180 190 200
pF1KE4 GTEEKNKAILLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTS
. .:. : . .: :. ..::.: :: ..: : :: :: :::. :.:.:...
XP_016 NLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVP
600 610 620 630 640 650
210 220 230 240 250 260
pF1KE4 EGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV
:::...: .:. . . .:.
XP_016 EGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVED
660 670 680 690 700 710
>>XP_011507661 (OMIM: 606524) SLIT-ROBO Rho GTPase-activ (841 aa)
initn: 280 init1: 147 opt: 293 Z-score: 342.8 bits: 72.8 E(91774): 2.5e-12
Smith-Waterman score: 293; 33.7% identity (65.7% similar) in 169 aa overlap (65-226:504-671)
40 50 60 70 80 90
pF1KE4 HETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTS-LEEH-IHTEGLFRKSGSV
:: ..:..: . .: .. ::.:: :::
XP_011 LQKTLGESQRTDCSLARRSSTVRKQDSSQAIP-LVVESCIRFISRHGLQHEGIFRVSGSQ
480 490 500 510 520 530
100 110 120 130 140
pF1KE4 IRLKALKNKVDHGEGCLSSAP---PCD-IAGLLKQFFRELPEPILPADL-HEALLKAQQL
.... .:: ..:: :.. : :::.:: .:: : .:..: :. :. . . .
XP_011 VEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMD
540 550 560 570 580 590
150 160 170 180 190 200
pF1KE4 GTEEKNKAILLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTS
. .:. : . .: :. ..::.: :: ..: : :: :: :::. :.:.:...
XP_011 NLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVP
600 610 620 630 640 650
210 220 230 240 250 260
pF1KE4 EGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV
:::...: .:. . . .:.
XP_011 EGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVED
660 670 680 690 700 710
>>XP_016856329 (OMIM: 606524) SLIT-ROBO Rho GTPase-activ (931 aa)
initn: 280 init1: 147 opt: 293 Z-score: 342.1 bits: 72.8 E(91774): 2.8e-12
Smith-Waterman score: 293; 33.7% identity (65.7% similar) in 169 aa overlap (65-226:351-518)
40 50 60 70 80 90
pF1KE4 HETAATEIGGKIFGVPFNALPHSAVPEYGHIPSFLVDACTS-LEEH-IHTEGLFRKSGSV
:: ..:..: . .: .. ::.:: :::
XP_016 LQKTLGESQRTDCSLARRSSTVRKQDSSQAIP-LVVESCIRFISRHGLQHEGIFRVSGSQ
330 340 350 360 370
100 110 120 130 140
pF1KE4 IRLKALKNKVDHGEGCLSSAP---PCD-IAGLLKQFFRELPEPILPADL-HEALLKAQQL
.... .:: ..:: :.. : :::.:: .:: : .:..: :. :. . . .
XP_016 VEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMD
380 390 400 410 420 430
150 160 170 180 190 200
pF1KE4 GTEEKNKAILLLSCLLADHTVHVLRYFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTS
. .:. : . .: :. ..::.: :: ..: : :: :: :::. :.:.:...
XP_016 NLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVP
440 450 460 470 480 490
210 220 230 240 250 260
pF1KE4 EGHEKMSSNAEKKGVYQTLSWKRYQPCWVLMVSVLLHHWKALKKVNMKLLVNIREREDNV
:::...: .:. . . .:.
XP_016 EGHDQVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVED
500 510 520 530 540 550
267 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 15:58:37 2019 done: Tue Jul 16 15:58:37 2019
Total Scan time: 3.420 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]