Result of FASTA (omim) for
pF1KE3815
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3815, 485 aa
1>>>pF1KE3815 485 - 485 aa - 485 aa
Library: /omim/omim.rfq.tfa
64704883 residues in 91410 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.3942+/-0.000424; mu= -5.9047+/- 0.026
mean_var=559.4730+/-113.338, 0's: 0 Z-trim(125.4): 44 B-trim: 862 in 1/60
Lambda= 0.054223
statistics sampled from 50730 (50802) to 50730 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.824), E-opt: 0.2 (0.556), width: 16
Scan time: 5.570
The best scores are: opt bits E(91410)
NP_001292997 (OMIM: 606009) double homeobox protei ( 424) 3014 250.2 9.2e-66
NP_001280727 (OMIM: 606009) double homeobox protei ( 424) 3014 250.2 9.2e-66
XP_024308351 (OMIM: 606009) double homeobox protei ( 424) 3001 249.2 1.9e-65
XP_024308352 (OMIM: 606009) double homeobox protei ( 424) 3001 249.2 1.9e-65
NP_001350749 (OMIM: 606009) double homeobox protei ( 160) 1103 100.1 5.1e-21
NP_036281 (OMIM: 611444) double homeobox protein 5 ( 197) 1080 98.5 2e-20
NP_036278 (OMIM: 611441) double homeobox protein 1 ( 170) 926 86.3 7.7e-17
>>NP_001292997 (OMIM: 606009) double homeobox protein 4 (424 aa)
initn: 3014 init1: 3014 opt: 3014 Z-score: 1302.2 bits: 250.2 E(91410): 9.2e-66
Smith-Waterman score: 3014; 100.0% identity (100.0% similar) in 424 aa overlap (62-485:1-424)
40 50 60 70 80 90
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
::::::::::::::::::::::::::::::
NP_001 MALPTPSDSTLPAEARGRGRRRRLVWTPSQ
10 20 30
100 110 120 130 140 150
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE3 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE3 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE3 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
340 350 360 370 380 390
460 470 480
pF1KE3 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
::::::::::::::::::::::::::::::::::
NP_001 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
400 410 420
>>NP_001280727 (OMIM: 606009) double homeobox protein 4 (424 aa)
initn: 3014 init1: 3014 opt: 3014 Z-score: 1302.2 bits: 250.2 E(91410): 9.2e-66
Smith-Waterman score: 3014; 100.0% identity (100.0% similar) in 424 aa overlap (62-485:1-424)
40 50 60 70 80 90
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
::::::::::::::::::::::::::::::
NP_001 MALPTPSDSTLPAEARGRGRRRRLVWTPSQ
10 20 30
100 110 120 130 140 150
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE3 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE3 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE3 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
340 350 360 370 380 390
460 470 480
pF1KE3 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
::::::::::::::::::::::::::::::::::
NP_001 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
400 410 420
>>XP_024308351 (OMIM: 606009) double homeobox protein 4- (424 aa)
initn: 3001 init1: 3001 opt: 3001 Z-score: 1296.7 bits: 249.2 E(91410): 1.9e-65
Smith-Waterman score: 3001; 99.5% identity (99.5% similar) in 424 aa overlap (62-485:1-424)
40 50 60 70 80 90
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
::::::::::::::::::::::::::::::
XP_024 MALPTPSDSTLPAEARGRGRRRRLVWTPSQ
10 20 30
100 110 120 130 140 150
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE3 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE3 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE3 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
:::::::::::::::::::::::::::::: :::::: ::::::::::::::::::::::
XP_024 PPPQPAPPDASASARQGQMQGIPAPSQALQXPAPWSAXPCGLLLDELLASPEFLQQAQPL
340 350 360 370 380 390
460 470 480
pF1KE3 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
::::::::::::::::::::::::::::::::::
XP_024 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
400 410 420
>>XP_024308352 (OMIM: 606009) double homeobox protein 4- (424 aa)
initn: 3001 init1: 3001 opt: 3001 Z-score: 1296.7 bits: 249.2 E(91410): 1.9e-65
Smith-Waterman score: 3001; 99.5% identity (99.5% similar) in 424 aa overlap (62-485:1-424)
40 50 60 70 80 90
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
::::::::::::::::::::::::::::::
XP_024 MALPTPSDSTLPAEARGRGRRRRLVWTPSQ
10 20 30
100 110 120 130 140 150
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE3 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 AARAAPALQPSQAAPAEGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPHPGKSREDR
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE3 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 DPQRDGLPGPCAVAQPGPAQAGPQGQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE3 PPPQPAPPDASASARQGQMQGIPAPSQALQEPAPWSALPCGLLLDELLASPEFLQQAQPL
:::::::::::::::::::::::::::::: :::::: ::::::::::::::::::::::
XP_024 PPPQPAPPDASASARQGQMQGIPAPSQALQXPAPWSAXPCGLLLDELLASPEFLQQAQPL
340 350 360 370 380 390
460 470 480
pF1KE3 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
::::::::::::::::::::::::::::::::::
XP_024 LETEAPGELEASEEAASLEAPLSEEEYRALLEEL
400 410 420
>>NP_001350749 (OMIM: 606009) double homeobox protein 4 (160 aa)
initn: 1128 init1: 1103 opt: 1103 Z-score: 499.0 bits: 100.1 E(91410): 5.1e-21
Smith-Waterman score: 1103; 100.0% identity (100.0% similar) in 159 aa overlap (62-220:1-159)
40 50 60 70 80 90
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
::::::::::::::::::::::::::::::
NP_001 MALPTPSDSTLPAEARGRGRRRRLVWTPSQ
10 20 30
100 110 120 130 140 150
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
:::::::::
NP_001 GQGGRAPAQV
160
>>NP_036281 (OMIM: 611444) double homeobox protein 5 [Ho (197 aa)
initn: 1341 init1: 1080 opt: 1080 Z-score: 488.2 bits: 98.5 E(91410): 2e-20
Smith-Waterman score: 1080; 82.1% identity (89.3% similar) in 196 aa overlap (36-231:2-197)
10 20 30 40 50 60
pF1KE3 LPACGPLQGRLAGWLAVRAGLLAAPAAVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALP
:::::::::::::: :::::::: :::
NP_036 MPAEVHGSPPASLCPCQSVKFRPGLPEMALL
10 20 30
70 80 90 100 110 120
pF1KE3 TPSDSTLPAEARGRGRRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQ
: :.::: ::.: ::: :. :::::.::::::::: ::::::.:.:::.: :::::::
NP_036 TALDDTLPEEAQGPGRRMILLSTPSQSDALRACFERNLYPGIATKEELAQGIDIPEPRVQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 IWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAR
:::::::: :::::::.:::::::: : .:::::::.:::::::::::::::::::::::
NP_036 IWFQNERSCQLRQHRRQSRPWPGRRDPQKGRRKRTAITGSQTALLLRAFEKDRFPGIAAR
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 EELARETGLPESRIQIWFQNRRARHPGQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTG
::::::::::::::::::::::::: ::.::::.::. :.::: :
NP_036 EELARETGLPESRIQIWFQNRRARHRGQSGRAPTQASIRCNAAPIG
160 170 180 190
250 260 270 280 290 300
pF1KE3 AWGTGLPAPHVPCAPGALPQGAFVSQAARAAPALQPSQAAPAEGISQPAPARGDFAYAAP
>>NP_036278 (OMIM: 611441) double homeobox protein 1 [Ho (170 aa)
initn: 1152 init1: 926 opt: 926 Z-score: 423.8 bits: 86.3 E(91410): 7.7e-17
Smith-Waterman score: 926; 81.8% identity (90.0% similar) in 170 aa overlap (62-231:1-170)
40 50 60 70 80 90
pF1KE3 AVHSPAEVHGSPPASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGRRRRLVWTPSQ
::: : :.::: ::.: ::: :. ::::
NP_036 MALLTALDDTLPEEAQGPGRRMILLSTPSQ
10 20 30
100 110 120 130 140 150
pF1KE3 SEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRG
:.::::::::: ::::::.:.:::.: ::::::::::::::: :::::::.::::::::
NP_036 SDALRACFERNLYPGIATKEELAQGIDIPEPRVQIWFQNERSCQLRQHRRQSRPWPGRRD
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 PPEGRRKRTAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHP
: .:::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PQKGRRKRTAITGSQTALLLRAFEKDRFPGIAAREELARETGLPESRIQIWFQNRRARHR
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE3 GQGGRAPAQAGGLCSAAPGGGHPAPSWVAFAHTGAWGTGLPAPHVPCAPGALPQGAFVSQ
::.::::.::. :.::: :
NP_036 GQSGRAPTQASIRCNAAPIG
160 170
485 residues in 1 query sequences
64704883 residues in 91410 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 24 16:39:25 2018 done: Tue Jul 24 16:39:26 2018
Total Scan time: 5.570 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]