Result of FASTA (omim) for
pF1KE3552
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3552, 1958 aa
1>>>pF1KE3552 1958 - 1958 aa - 1958 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4882+/-0.000466; mu= -0.4403+/- 0.029
mean_var=234.5495+/-47.798, 0's: 0 Z-trim(117.2): 425 B-trim: 683 in 1/51
Lambda= 0.083745
statistics sampled from 29575 (30030) to 29575 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.327), width: 16
Scan time: 10.740
The best scores are: opt bits E(91774)
NP_001354377 (OMIM: 609870) rho GTPase-activating (1958) 12840 1566.1 0
NP_065875 (OMIM: 609870) rho GTPase-activating pro (1958) 12840 1566.1 0
XP_016871948 (OMIM: 609870) rho GTPase-activating (1958) 12840 1566.1 0
NP_001354383 (OMIM: 609870) rho GTPase-activating (1958) 12840 1566.1 0
NP_001354379 (OMIM: 609870) rho GTPase-activating (1860) 12183 1486.7 0
NP_001354378 (OMIM: 609870) rho GTPase-activating (1860) 12183 1486.7 0
NP_001354381 (OMIM: 609870) rho GTPase-activating (1801) 11760 1435.6 0
NP_001354382 (OMIM: 609870) rho GTPase-activating (1948) 11720 1430.7 0
NP_001354380 (OMIM: 609870) rho GTPase-activating (1948) 11720 1430.7 0
NP_001354376 (OMIM: 609870) rho GTPase-activating (1948) 11720 1430.7 0
NP_001354384 (OMIM: 609870) rho GTPase-activating (1745) 11424 1395.0 0
XP_024303856 (OMIM: 609870) rho GTPase-activating (1914) 7495 920.3 0
XP_011517908 (OMIM: 609870) rho GTPase-activating (1924) 7495 920.3 0
XP_011517907 (OMIM: 609870) rho GTPase-activating (1982) 7495 920.3 0
XP_011517904 (OMIM: 609870) rho GTPase-activating (1992) 7495 920.3 0
XP_011517906 (OMIM: 609870) rho GTPase-activating (1992) 7495 920.3 0
XP_011517905 (OMIM: 609870) rho GTPase-activating (1992) 7495 920.3 0
XP_011517909 (OMIM: 609870) rho GTPase-activating (1491) 5354 661.6 1.9e-188
XP_011523377 (OMIM: 610590) rho GTPase-activating (1285) 1488 194.5 6.7e-48
XP_011523376 (OMIM: 610590) rho GTPase-activating (1397) 1488 194.5 7.2e-48
XP_006722054 (OMIM: 610590) rho GTPase-activating (1473) 1488 194.5 7.5e-48
XP_011523375 (OMIM: 610590) rho GTPase-activating (1476) 1488 194.5 7.5e-48
NP_001186346 (OMIM: 610590) rho GTPase-activating (1491) 1488 194.5 7.6e-48
XP_011523378 (OMIM: 610590) rho GTPase-activating (1159) 1370 180.2 1.2e-43
XP_024306615 (OMIM: 610590) rho GTPase-activating (1144) 1339 176.4 1.6e-42
XP_006722055 (OMIM: 610590) rho GTPase-activating (1408) 1313 173.3 1.7e-41
XP_006722056 (OMIM: 610590) rho GTPase-activating (1249) 1284 169.8 1.7e-40
XP_011523379 (OMIM: 610590) rho GTPase-activating (1117) 1259 166.8 1.3e-39
XP_016880391 (OMIM: 610590) rho GTPase-activating (1119) 1259 166.8 1.3e-39
XP_016872443 (OMIM: 610577) rho GTPase-activating ( 742) 501 75.1 3.2e-12
NP_001257627 (OMIM: 610577) rho GTPase-activating ( 769) 501 75.1 3.3e-12
XP_011518063 (OMIM: 610577) rho GTPase-activating ( 772) 501 75.1 3.4e-12
NP_001257628 (OMIM: 610577) rho GTPase-activating ( 794) 501 75.1 3.4e-12
XP_005252701 (OMIM: 610577) rho GTPase-activating ( 794) 501 75.1 3.4e-12
NP_001257626 (OMIM: 610577) rho GTPase-activating ( 799) 501 75.1 3.5e-12
NP_001257625 (OMIM: 610577) rho GTPase-activating ( 816) 501 75.1 3.5e-12
NP_001257624 (OMIM: 610577) rho GTPase-activating ( 841) 501 75.1 3.6e-12
NP_060757 (OMIM: 610577) rho GTPase-activating pro ( 846) 501 75.1 3.6e-12
XP_011509785 (OMIM: 610578) rho GTPase-activating ( 397) 488 73.4 5.6e-12
XP_016859989 (OMIM: 610578) rho GTPase-activating ( 432) 488 73.5 6e-12
XP_011509781 (OMIM: 610578) rho GTPase-activating ( 475) 488 73.5 6.5e-12
XP_016859988 (OMIM: 610578) rho GTPase-activating ( 475) 488 73.5 6.5e-12
NP_060930 (OMIM: 610578) rho GTPase-activating pro ( 475) 488 73.5 6.5e-12
XP_024308769 (OMIM: 610578) rho GTPase-activating ( 241) 462 70.2 3.2e-11
XP_024308768 (OMIM: 610578) rho GTPase-activating ( 241) 462 70.2 3.2e-11
NP_001193531 (OMIM: 118423,604356) N-chimaerin iso ( 334) 453 69.2 9e-11
NP_001020372 (OMIM: 118423,604356) N-chimaerin iso ( 433) 453 69.2 1.1e-10
NP_001813 (OMIM: 118423,604356) N-chimaerin isofor ( 459) 453 69.2 1.2e-10
NP_001280010 (OMIM: 602857) beta-chimaerin isoform ( 261) 446 68.3 1.3e-10
NP_001280002 (OMIM: 602857) beta-chimaerin isoform ( 287) 446 68.3 1.4e-10
>>NP_001354377 (OMIM: 609870) rho GTPase-activating prot (1958 aa)
initn: 12840 init1: 12840 opt: 12840 Z-score: 8391.0 bits: 1566.1 E(91774): 0
Smith-Waterman score: 12840; 100.0% identity (100.0% similar) in 1958 aa overlap (1-1958:1-1958)
10 20 30 40 50 60
pF1KE3 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE3 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE3 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
1870 1880 1890 1900 1910 1920
1930 1940 1950
pF1KE3 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
::::::::::::::::::::::::::::::::::::::
NP_001 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
1930 1940 1950
>>NP_065875 (OMIM: 609870) rho GTPase-activating protein (1958 aa)
initn: 12840 init1: 12840 opt: 12840 Z-score: 8391.0 bits: 1566.1 E(91774): 0
Smith-Waterman score: 12840; 100.0% identity (100.0% similar) in 1958 aa overlap (1-1958:1-1958)
10 20 30 40 50 60
pF1KE3 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE3 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE3 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
1870 1880 1890 1900 1910 1920
1930 1940 1950
pF1KE3 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
::::::::::::::::::::::::::::::::::::::
NP_065 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
1930 1940 1950
>>XP_016871948 (OMIM: 609870) rho GTPase-activating prot (1958 aa)
initn: 12840 init1: 12840 opt: 12840 Z-score: 8391.0 bits: 1566.1 E(91774): 0
Smith-Waterman score: 12840; 100.0% identity (100.0% similar) in 1958 aa overlap (1-1958:1-1958)
10 20 30 40 50 60
pF1KE3 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE3 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE3 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
1870 1880 1890 1900 1910 1920
1930 1940 1950
pF1KE3 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
::::::::::::::::::::::::::::::::::::::
XP_016 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
1930 1940 1950
>>NP_001354383 (OMIM: 609870) rho GTPase-activating prot (1958 aa)
initn: 12840 init1: 12840 opt: 12840 Z-score: 8391.0 bits: 1566.1 E(91774): 0
Smith-Waterman score: 12840; 100.0% identity (100.0% similar) in 1958 aa overlap (1-1958:1-1958)
10 20 30 40 50 60
pF1KE3 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE3 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE3 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
1870 1880 1890 1900 1910 1920
1930 1940 1950
pF1KE3 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
::::::::::::::::::::::::::::::::::::::
NP_001 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
1930 1940 1950
>>NP_001354379 (OMIM: 609870) rho GTPase-activating prot (1860 aa)
initn: 12183 init1: 12183 opt: 12183 Z-score: 7962.4 bits: 1486.7 E(91774): 0
Smith-Waterman score: 12183; 100.0% identity (100.0% similar) in 1860 aa overlap (99-1958:1-1860)
70 80 90 100 110 120
pF1KE3 VYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCTGDRIIKVN
::::::::::::::::::::::::::::::
NP_001 MDTIFVKQVKEGGPAFEAGLCTGDRIIKVN
10 20 30
130 140 150 160 170 180
pF1KE3 GESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQDAYLKGNEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQDAYLKGNEA
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 YSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQPGRAYRMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQPGRAYRMEI
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 QVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEEVRYGVSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEEVRYGVSEQ
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 TSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISSSRSQAVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISSSRSQAVEA
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 PSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSTTDYNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSTTDYNQV
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 VPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPSVSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPSVSF
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE3 SNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGICERPRQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGICERPRQQE
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE3 IHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQTTCGMSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQTTCGMSLP
460 470 480 490 500 510
610 620 630 640 650 660
pF1KE3 RGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSLLNQQTWVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSLLNQQTWVR
520 530 540 550 560 570
670 680 690 700 710 720
pF1KE3 TDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQEAETEQSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQEAETEQSDT
580 590 600 610 620 630
730 740 750 760 770 780
pF1KE3 LDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARREVHIKRMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARREVHIKRMEE
640 650 660 670 680 690
790 800 810 820 830 840
pF1KE3 RKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIATVPPCLTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIATVPPCLTTS
700 710 720 730 740 750
850 860 870 880 890 900
pF1KE3 APLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKI
760 770 780 790 800 810
910 920 930 940 950 960
pF1KE3 ADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGH
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KE3 SLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDM
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KE3 LAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQTLLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQTLLGA
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KE3 KSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVR
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KE3 LDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDI
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KE3 QDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPE
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KE3 HHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIV
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KE3 ETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATS
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420 1430 1440
pF1KE3 DSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNVFFKKENVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNVFFKKENVE
1300 1310 1320 1330 1340 1350
1450 1460 1470 1480 1490 1500
pF1KE3 QCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPSEEPSPPHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPSEEPSPPHN
1360 1370 1380 1390 1400 1410
1510 1520 1530 1540 1550 1560
pF1KE3 SKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLARFSMKKSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLARFSMKKSTS
1420 1430 1440 1450 1460 1470
1570 1580 1590 1600 1610 1620
pF1KE3 PETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEADDERSELIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEADDERSELIS
1480 1490 1500 1510 1520 1530
1630 1640 1650 1660 1670 1680
pF1KE3 EGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGSLTSSLDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGSLTSSLDSR
1540 1550 1560 1570 1580 1590
1690 1700 1710 1720 1730 1740
pF1KE3 RQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLLT
1600 1610 1620 1630 1640 1650
1750 1760 1770 1780 1790 1800
pF1KE3 PTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRRRHTLGGHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRRRHTLGGHR
1660 1670 1680 1690 1700 1710
1810 1820 1830 1840 1850 1860
pF1KE3 DATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRTSTSDLSRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRTSTSDLSRG
1720 1730 1740 1750 1760 1770
1870 1880 1890 1900 1910 1920
pF1KE3 EIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQINGESFQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQINGESFQN
1780 1790 1800 1810 1820 1830
1930 1940 1950
pF1KE3 VSKNASSAANAQPHKLSETPGSKAEFHPCL
::::::::::::::::::::::::::::::
NP_001 VSKNASSAANAQPHKLSETPGSKAEFHPCL
1840 1850 1860
>>NP_001354378 (OMIM: 609870) rho GTPase-activating prot (1860 aa)
initn: 12183 init1: 12183 opt: 12183 Z-score: 7962.4 bits: 1486.7 E(91774): 0
Smith-Waterman score: 12183; 100.0% identity (100.0% similar) in 1860 aa overlap (99-1958:1-1860)
70 80 90 100 110 120
pF1KE3 VYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCTGDRIIKVN
::::::::::::::::::::::::::::::
NP_001 MDTIFVKQVKEGGPAFEAGLCTGDRIIKVN
10 20 30
130 140 150 160 170 180
pF1KE3 GESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQDAYLKGNEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQDAYLKGNEA
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 YSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQPGRAYRMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQPGRAYRMEI
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 QVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEEVRYGVSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEEVRYGVSEQ
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 TSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISSSRSQAVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISSSRSQAVEA
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 PSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSTTDYNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSTTDYNQV
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 VPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPSVSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPSVSF
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE3 SNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGICERPRQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGICERPRQQE
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE3 IHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQTTCGMSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQTTCGMSLP
460 470 480 490 500 510
610 620 630 640 650 660
pF1KE3 RGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSLLNQQTWVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSLLNQQTWVR
520 530 540 550 560 570
670 680 690 700 710 720
pF1KE3 TDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQEAETEQSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQEAETEQSDT
580 590 600 610 620 630
730 740 750 760 770 780
pF1KE3 LDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARREVHIKRMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARREVHIKRMEE
640 650 660 670 680 690
790 800 810 820 830 840
pF1KE3 RKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIATVPPCLTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIATVPPCLTTS
700 710 720 730 740 750
850 860 870 880 890 900
pF1KE3 APLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKI
760 770 780 790 800 810
910 920 930 940 950 960
pF1KE3 ADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGH
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KE3 SLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDM
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KE3 LAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQTLLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQTLLGA
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KE3 KSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVR
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KE3 LDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDI
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KE3 QDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPE
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KE3 HHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIV
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KE3 ETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATS
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420 1430 1440
pF1KE3 DSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNVFFKKENVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNVFFKKENVE
1300 1310 1320 1330 1340 1350
1450 1460 1470 1480 1490 1500
pF1KE3 QCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPSEEPSPPHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPSEEPSPPHN
1360 1370 1380 1390 1400 1410
1510 1520 1530 1540 1550 1560
pF1KE3 SKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLARFSMKKSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLARFSMKKSTS
1420 1430 1440 1450 1460 1470
1570 1580 1590 1600 1610 1620
pF1KE3 PETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEADDERSELIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEADDERSELIS
1480 1490 1500 1510 1520 1530
1630 1640 1650 1660 1670 1680
pF1KE3 EGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGSLTSSLDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGSLTSSLDSR
1540 1550 1560 1570 1580 1590
1690 1700 1710 1720 1730 1740
pF1KE3 RQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLLT
1600 1610 1620 1630 1640 1650
1750 1760 1770 1780 1790 1800
pF1KE3 PTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRRRHTLGGHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRRRHTLGGHR
1660 1670 1680 1690 1700 1710
1810 1820 1830 1840 1850 1860
pF1KE3 DATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRTSTSDLSRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRTSTSDLSRG
1720 1730 1740 1750 1760 1770
1870 1880 1890 1900 1910 1920
pF1KE3 EIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQINGESFQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQINGESFQN
1780 1790 1800 1810 1820 1830
1930 1940 1950
pF1KE3 VSKNASSAANAQPHKLSETPGSKAEFHPCL
::::::::::::::::::::::::::::::
NP_001 VSKNASSAANAQPHKLSETPGSKAEFHPCL
1840 1850 1860
>>NP_001354381 (OMIM: 609870) rho GTPase-activating prot (1801 aa)
initn: 11760 init1: 11760 opt: 11760 Z-score: 7686.4 bits: 1435.6 E(91774): 0
Smith-Waterman score: 11760; 100.0% identity (100.0% similar) in 1793 aa overlap (166-1958:9-1801)
140 150 160 170 180 190
pF1KE3 TYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQDAYLKGNEAYSGNARN
::::::::::::::::::::::::::::::
NP_001 MKKMETEELQFTKDVTALAYSQDAYLKGNEAYSGNARN
10 20 30
200 210 220 230 240 250
pF1KE3 IPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQPGRAYRMEIQVPPSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQPGRAYRMEIQVPPSPT
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE3 DVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEEVRYGVSEQTSLKTVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEEVRYGVSEQTSLKTVS
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE3 RTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISSSRSQAVEAPSVSVNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISSSRSQAVEAPSVSVNH
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE3 YSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSTTDYNQVVPNRTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQSTTDYNQVVPNRTTL
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE3 QGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPSVSFSNHRTRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGALTSPSVSFSNHRTRS
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE3 WDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGICERPRQQEIHKSFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGICERPRQQEIHKSFRG
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE3 SNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQTTCGMSLPRGISQDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQTTCGMSLPRGISQDR
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE3 SPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSLLNQQTWVRTDSAPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSLLNQQTWVRTDSAPDQ
460 470 480 490 500 510
680 690 700 710 720 730
pF1KE3 QVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQEAETEQSDTLDNKEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQEAETEQSDTLDNKEAV
520 530 540 550 560 570
740 750 760 770 780 790
pF1KE3 ILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARREVHIKRMEERKASSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARREVHIKRMEERKASSTS
580 590 600 610 620 630
800 810 820 830 840 850
pF1KE3 PPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIATVPPCLTTSAPLIRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIATVPPCLTTSAPLIRRQ
640 650 660 670 680 690
860 870 880 890 900 910
pF1KE3 LSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKIADSQKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVSSLKGIKIADSQKSS
700 710 720 730 740 750
920 930 940 950 960 970
pF1KE3 EDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKD
760 770 780 790 800 810
980 990 1000 1010 1020 1030
pF1KE3 KREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDMLAWIKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDMLAWIKTI
820 830 840 850 860 870
1040 1050 1060 1070 1080 1090
pF1KE3 QESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQTLLGAKSEPKTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQTLLGAKSEPKTQ
880 890 900 910 920 930
1100 1110 1120 1130 1140 1150
pF1KE3 SPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVRLDDCPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGVRLDDCPPA
940 950 960 970 980 990
1160 1170 1180 1190 1200 1210
pF1KE3 HTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRD
1000 1010 1020 1030 1040 1050
1220 1230 1240 1250 1260 1270
pF1KE3 LNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLK
1060 1070 1080 1090 1100 1110
1280 1290 1300 1310 1320 1330
pF1KE3 FLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHH
1120 1130 1140 1150 1160 1170
1340 1350 1360 1370 1380 1390
pF1KE3 DWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATSDSTKSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPGDVSDSATSDSTKSKG
1180 1190 1200 1210 1220 1230
1400 1410 1420 1430 1440 1450
pF1KE3 SWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNVFFKKENVEQCHNDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNVFFKKENVEQCHNDTK
1240 1250 1260 1270 1280 1290
1460 1470 1480 1490 1500 1510
pF1KE3 EESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPSEEPSPPHNSKHNKSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPSEEPSPPHNSKHNKSP
1300 1310 1320 1330 1340 1350
1520 1530 1540 1550 1560 1570
pF1KE3 TLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLARFSMKKSTSPETKHSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLARFSMKKSTSPETKHSE
1360 1370 1380 1390 1400 1410
1580 1590 1600 1610 1620 1630
pF1KE3 FLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEADDERSELISEGRPVET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEADDERSELISEGRPVET
1420 1430 1440 1450 1460 1470
1640 1650 1660 1670 1680 1690
pF1KE3 DSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGSLTSSLDSRRQLFSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGSLTSSLDSRRQLFSSH
1480 1490 1500 1510 1520 1530
1700 1710 1720 1730 1740 1750
pF1KE3 KLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLLTPTRGESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKGKSTGSLLTPTRGESE
1540 1550 1560 1570 1580 1590
1760 1770 1780 1790 1800 1810
pF1KE3 KQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRRRHTLGGHRDATEISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRRRHTLGGHRDATEISV
1600 1610 1620 1630 1640 1650
1820 1830 1840 1850 1860 1870
pF1KE3 LNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRTSTSDLSRGEIGDPQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRTSTSDLSRGEIGDPQT
1660 1670 1680 1690 1700 1710
1880 1890 1900 1910 1920 1930
pF1KE3 ENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQINGESFQNVSKNASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQINGESFQNVSKNASS
1720 1730 1740 1750 1760 1770
1940 1950
pF1KE3 AANAQPHKLSETPGSKAEFHPCL
:::::::::::::::::::::::
NP_001 AANAQPHKLSETPGSKAEFHPCL
1780 1790 1800
>>NP_001354382 (OMIM: 609870) rho GTPase-activating prot (1948 aa)
initn: 11713 init1: 11713 opt: 11720 Z-score: 7659.7 bits: 1430.7 E(91774): 0
Smith-Waterman score: 12751; 99.5% identity (99.5% similar) in 1958 aa overlap (1-1958:1-1948)
10 20 30 40 50 60
pF1KE3 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_001 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQV----------AYSQD
130 140 150 160 170
190 200 210 220 230 240
pF1KE3 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE3 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE3 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE3 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE3 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE3 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE3 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE3 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE3 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE3 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE3 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE3 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE3 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE3 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE3 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE3 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE3 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE3 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE3 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE3 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE3 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KE3 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KE3 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE3 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE3 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KE3 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
1860 1870 1880 1890 1900 1910
1930 1940 1950
pF1KE3 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
::::::::::::::::::::::::::::::::::::::
NP_001 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
1920 1930 1940
>>NP_001354380 (OMIM: 609870) rho GTPase-activating prot (1948 aa)
initn: 11713 init1: 11713 opt: 11720 Z-score: 7659.7 bits: 1430.7 E(91774): 0
Smith-Waterman score: 12751; 99.5% identity (99.5% similar) in 1958 aa overlap (1-1958:1-1948)
10 20 30 40 50 60
pF1KE3 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_001 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQV----------AYSQD
130 140 150 160 170
190 200 210 220 230 240
pF1KE3 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE3 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE3 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE3 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE3 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE3 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE3 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE3 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE3 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE3 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE3 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE3 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE3 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE3 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE3 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE3 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE3 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE3 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE3 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE3 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE3 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KE3 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KE3 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE3 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE3 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KE3 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
1860 1870 1880 1890 1900 1910
1930 1940 1950
pF1KE3 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
::::::::::::::::::::::::::::::::::::::
NP_001 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
1920 1930 1940
>>NP_001354376 (OMIM: 609870) rho GTPase-activating prot (1948 aa)
initn: 11713 init1: 11713 opt: 11720 Z-score: 7659.7 bits: 1430.7 E(91774): 0
Smith-Waterman score: 12751; 99.5% identity (99.5% similar) in 1958 aa overlap (1-1958:1-1948)
10 20 30 40 50 60
pF1KE3 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSWPGPKTVTLKRTSQGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIFVKQVKEGGPAFEAGLCT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQVLQFTKDVTALAYSQD
::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_001 GDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDEDILQV----------AYSQD
130 140 150 160 170
190 200 210 220 230 240
pF1KE3 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVEISPPDSSLSKQQTSTPVLTQP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVPSEKVVDLLSNRNNHTGPSHRTEE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRYGVSEQTSLKTVSRTTSPPLSIPTTHLIHQPAGSRSLEPSGILLKSGNYSGHSDGISS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYKEYIDNRRLHIGCRTIQERLDSLRAASQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE3 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STTDYNQVVPNRTTLQGRRRSTSHDRVPQSVQIRQRSVSQERLEDSVLMKYCPRSASQGA
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE3 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSPSVSFSNHRTRSWDYIEGQDETLENVNSGTPIPDSNGEKKQTYKWSGFTEQDDRRGI
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE3 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CERPRQQEIHKSFRGSNFTVAPSVVNSDNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE3 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTCGMSLPRGISQDRSPLVKVRSNSLKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE3 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNQQTWVRTDSAPDQQVETGKSPSLSGASAKPAPQSSENAGTSDLELPVSQRNQDLSLQE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE3 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AETEQSDTLDNKEAVILREKPPSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARRE
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE3 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHIKRMEERKASSTSPPGDSLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIAT
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE3 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPPCLTTSAPLIRRQLSHDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE3 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLKGIKIADSQKSSEDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQ
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE3 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYVVLRGHSLYLYKDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLF
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE3 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAEDRDDMLAWIKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLS
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE3 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRQTLLGAKSEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPT
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE3 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELN
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE3 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLK
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE3 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTH
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE3 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSPG
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE3 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDELDNV
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE3 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGKESTPS
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE3 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTSSQASLAR
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE3 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSVAESKGDEAD
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KE3 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNSEGSELSCTEGS
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KE3 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEAPSLTKVFDVMKKG
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE3 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGVGNHKVNAETAKRKSIRR
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE3 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCSAQDLSISDWLARERLRT
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KE3 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSSTLASTNRPLLSIPPQSPDQ
1860 1870 1880 1890 1900 1910
1930 1940 1950
pF1KE3 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
::::::::::::::::::::::::::::::::::::::
NP_001 INGESFQNVSKNASSAANAQPHKLSETPGSKAEFHPCL
1920 1930 1940
1958 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 15:56:43 2019 done: Tue Jul 16 15:56:45 2019
Total Scan time: 10.740 Total Display time: 0.830
Function used was FASTA [36.3.4 Apr, 2011]