Result of FASTA (omim) for
pF1KE3491
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3491, 1865 aa
1>>>pF1KE3491 1865 - 1865 aa - 1865 aa
Library: /omim/omim.rfq.tfa
61573307 residues in 86401 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8087+/-0.000543; mu= 16.1636+/- 0.033
mean_var=90.5831+/-18.507, 0's: 0 Z-trim(109.0): 145 B-trim: 329 in 2/50
Lambda= 0.134757
statistics sampled from 17134 (17279) to 17134 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.542), E-opt: 0.2 (0.2), width: 16
Scan time: 16.120
The best scores are: opt bits E(86401)
NP_060142 (OMIM: 105500,605692) transient receptor (1865) 12491 2440.2 0
XP_016877841 (OMIM: 105500,605692) PREDICTED: tran (1874) 12484 2438.8 0
NP_001288141 (OMIM: 105500,605692) transient recep (1864) 12474 2436.9 0
XP_016877842 (OMIM: 105500,605692) PREDICTED: tran (1873) 12467 2435.5 0
XP_005254543 (OMIM: 105500,605692) PREDICTED: tran (1885) 9783 1913.7 0
XP_016877840 (OMIM: 105500,605692) PREDICTED: tran (1893) 9778 1912.7 0
XP_016877839 (OMIM: 105500,605692) PREDICTED: tran (1894) 9776 1912.4 0
XP_016877843 (OMIM: 105500,605692) PREDICTED: tran (1826) 9353 1830.1 0
XP_016877844 (OMIM: 105500,605692) PREDICTED: tran (1826) 9353 1830.1 0
XP_016877845 (OMIM: 105500,605692) PREDICTED: tran (1069) 7021 1376.7 0
XP_016870641 (OMIM: 608961) PREDICTED: transient r (1362) 3176 629.2 8.6e-179
XP_016870637 (OMIM: 608961) PREDICTED: transient r (1364) 3176 629.2 8.6e-179
XP_011517338 (OMIM: 608961) PREDICTED: transient r (1744) 3176 629.2 1.1e-178
XP_011517337 (OMIM: 608961) PREDICTED: transient r (1746) 3176 629.2 1.1e-178
XP_011517339 (OMIM: 608961) PREDICTED: transient r (1734) 3051 604.9 2.2e-171
XP_016870630 (OMIM: 608961) PREDICTED: transient r (1736) 3051 604.9 2.2e-171
XP_016870643 (OMIM: 608961) PREDICTED: transient r (1352) 3048 604.3 2.7e-171
XP_016870638 (OMIM: 608961) PREDICTED: transient r (1354) 3048 604.3 2.7e-171
XP_016870639 (OMIM: 608961) PREDICTED: transient r (1352) 3045 603.7 4e-171
XP_011517340 (OMIM: 608961) PREDICTED: transient r (1732) 3045 603.8 5e-171
XP_016870631 (OMIM: 608961) PREDICTED: transient r (1734) 3045 603.8 5e-171
XP_016870650 (OMIM: 608961) PREDICTED: transient r (1106) 2834 562.7 7.4e-159
XP_016870645 (OMIM: 608961) PREDICTED: transient r (1290) 2488 495.4 1.5e-138
XP_016870646 (OMIM: 608961) PREDICTED: transient r (1315) 2391 476.6 7.3e-133
XP_011517348 (OMIM: 608961) PREDICTED: transient r (1697) 2391 476.6 9.2e-133
XP_011517347 (OMIM: 608961) PREDICTED: transient r (1699) 2391 476.6 9.2e-133
XP_011517349 (OMIM: 608961) PREDICTED: transient r (1325) 2383 475.0 2.2e-132
XP_016870642 (OMIM: 608961) PREDICTED: transient r (1327) 2383 475.0 2.2e-132
NP_001007472 (OMIM: 608961) transient receptor pot (1707) 2383 475.0 2.7e-132
XP_011517345 (OMIM: 608961) PREDICTED: transient r (1709) 2383 475.0 2.7e-132
NP_996827 (OMIM: 608961) transient receptor potent (1544) 2180 435.6 1.9e-120
XP_016870649 (OMIM: 608961) PREDICTED: transient r (1172) 2172 434.0 4.3e-120
NP_066003 (OMIM: 608961) transient receptor potent (1554) 2172 434.0 5.6e-120
XP_016870647 (OMIM: 608961) PREDICTED: transient r (1260) 2143 428.4 2.3e-118
XP_016870644 (OMIM: 608961) PREDICTED: transient r (1337) 2143 428.4 2.4e-118
XP_016870640 (OMIM: 608961) PREDICTED: transient r (1339) 2143 428.4 2.4e-118
XP_011517346 (OMIM: 608961) PREDICTED: transient r (1709) 2143 428.4 3e-118
XP_011517344 (OMIM: 608961) PREDICTED: transient r (1711) 2143 428.4 3e-118
XP_011517343 (OMIM: 608961) PREDICTED: transient r (1719) 2143 428.4 3e-118
XP_011517342 (OMIM: 608961) PREDICTED: transient r (1721) 2143 428.4 3.1e-118
NP_002411 (OMIM: 603576,613216) transient receptor (1603) 1991 398.8 2.2e-109
NP_001238953 (OMIM: 603576,613216) transient recep (1625) 1991 398.8 2.3e-109
NP_001238949 (OMIM: 603576,613216) transient recep (1642) 1991 398.8 2.3e-109
XP_016870648 (OMIM: 608961) PREDICTED: transient r (1184) 1932 387.3 4.8e-106
NP_996828 (OMIM: 608961) transient receptor potent (1556) 1932 387.4 6.2e-106
NP_079247 (OMIM: 608961) transient receptor potent (1566) 1932 387.4 6.2e-106
XP_011516546 (OMIM: 602014,607009) PREDICTED: tran (2021) 1522 307.7 7.8e-82
XP_011516553 (OMIM: 602014,607009) PREDICTED: tran (1779) 1511 305.5 3.1e-81
XP_016869777 (OMIM: 602014,607009) PREDICTED: tran (1852) 1511 305.5 3.2e-81
XP_016869776 (OMIM: 602014,607009) PREDICTED: tran (1901) 1511 305.5 3.2e-81
>>NP_060142 (OMIM: 105500,605692) transient receptor pot (1865 aa)
initn: 12491 init1: 12491 opt: 12491 Z-score: 13115.9 bits: 2440.2 E(86401): 0
Smith-Waterman score: 12491; 100.0% identity (100.0% similar) in 1865 aa overlap (1-1865:1-1865)
10 20 30 40 50 60
pF1KE3 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 DIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 KRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 SMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNST
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 CLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQMKSKKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQMKSKKLP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 ITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 VREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 GRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 LFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 LFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 FERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 HNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNNPFHCNILMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNNPFHCNILMK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 DDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHGVELLKIFNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHGVELLKIFNK
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 NQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATEGDNTEFGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATEGDNTEFGAF
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 VGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKIS
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 RRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVER
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 NNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMG
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 GGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRA
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 AQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIP
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 TNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGE
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE3 DAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNS
1810 1820 1830 1840 1850 1860
pF1KE3 VRLML
:::::
NP_060 VRLML
>>XP_016877841 (OMIM: 105500,605692) PREDICTED: transien (1874 aa)
initn: 12484 init1: 12484 opt: 12484 Z-score: 13108.5 bits: 2438.8 E(86401): 0
Smith-Waterman score: 12484; 100.0% identity (100.0% similar) in 1864 aa overlap (2-1865:11-1874)
10 20 30 40 50
pF1KE3 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQH
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPPKVLGLQSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 ACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 SYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 LTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 LSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 KTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 ILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 PRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 RFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 DTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 ALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTY
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 ELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAI
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 LLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEME
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 IQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 YIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFAN
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE3 AYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE3 LSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTW
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE3 LTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPP
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE3 LIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE3 GSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTA
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE3 QKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNN
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE3 PFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHG
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE3 VELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATE
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE3 GDNTEFGAFVGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDNTEFGAFVGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPV
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE3 HSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDT
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KE3 NYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKI
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KE3 EFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLC
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KE3 LREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYN
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KE3 NNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDM
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KE3 VFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNS
1810 1820 1830 1840 1850 1860
1860
pF1KE3 TKESESTNSVRLML
::::::::::::::
XP_016 TKESESTNSVRLML
1870
>>NP_001288141 (OMIM: 105500,605692) transient receptor (1864 aa)
initn: 9982 init1: 9982 opt: 12474 Z-score: 13098.1 bits: 2436.9 E(86401): 0
Smith-Waterman score: 12474; 99.9% identity (99.9% similar) in 1865 aa overlap (1-1865:1-1864)
10 20 30 40 50 60
pF1KE3 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 DIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 KRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 SMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNST
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 CLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQMKSKKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQMKSKKLP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 ITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 VREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 GRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 LFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 LFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 FERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 HNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNNPFHCNILMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNNPFHCNILMK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 DDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHGVELLKIFNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHGVELLKIFNK
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 NQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATEGDNTEFGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATEGDNTEFGAF
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 VGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 VGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQ-EKIS
1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE3 RRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVER
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE3 NNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMG
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KE3 GGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRA
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KE3 AQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIP
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE3 TNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGE
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE3 DAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNS
1800 1810 1820 1830 1840 1850
pF1KE3 VRLML
:::::
NP_001 VRLML
1860
>>XP_016877842 (OMIM: 105500,605692) PREDICTED: transien (1873 aa)
initn: 9975 init1: 9975 opt: 12467 Z-score: 13090.7 bits: 2435.5 E(86401): 0
Smith-Waterman score: 12467; 99.9% identity (99.9% similar) in 1864 aa overlap (2-1865:11-1873)
10 20 30 40 50
pF1KE3 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQH
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPPKVLGLQSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 ACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 SYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 LTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 LSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 KTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 ILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 PRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 RFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 DTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 ALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTY
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 ELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAI
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 LLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEME
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 IQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 YIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFAN
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE3 AYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE3 LSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTW
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE3 LTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPP
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE3 LIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE3 GSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTA
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE3 QKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNN
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE3 PFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHG
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE3 VELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATE
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE3 GDNTEFGAFVGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDNTEFGAFVGHRDSMDLQRFKETSNKIKILSNNNTSENTLKRVSSLAGFTDCHRTSIPV
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE3 HSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDT
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSKQ-EKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDT
1510 1520 1530 1540 1550
1560 1570 1580 1590 1600 1610
pF1KE3 NYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKI
1560 1570 1580 1590 1600 1610
1620 1630 1640 1650 1660 1670
pF1KE3 EFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLC
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KE3 LREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYN
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KE3 NNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDM
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KE3 VFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNS
1800 1810 1820 1830 1840 1850
1860
pF1KE3 TKESESTNSVRLML
::::::::::::::
XP_016 TKESESTNSVRLML
1860 1870
>>XP_005254543 (OMIM: 105500,605692) PREDICTED: transien (1885 aa)
initn: 12477 init1: 9773 opt: 9783 Z-score: 10270.6 bits: 1913.7 E(86401): 0
Smith-Waterman score: 12441; 98.9% identity (98.9% similar) in 1885 aa overlap (1-1865:1-1885)
10 20 30 40 50 60
pF1KE3 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQHACFTASLAM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRLSYDTKPEVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWILTGGVNTGV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNPLSKLNVLNN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFEGGPNVILTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIKKTFNFGQNE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQLILTLAWDRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 DIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTIPRLEELYNT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRKRFRLIYNSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKIDTVMEEGKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 KRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAKALVACKIYR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 SMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTYELKNWSNST
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 CLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAILLLEYKTKA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQMKSKKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEMEIQMKSKKLP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 ITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIAYIFTYAIEK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 VREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNHVFVA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 GRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGVPRKA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTWLTPFLQAVY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 LFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPPLIILSHIVS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 LFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHSGSEERIRVT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 FERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTAQKASEASKV
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 HNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNNPFHCNILMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNNPFHCNILMK
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 DDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHGVELLKIFNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHGVELLKIFNK
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 NQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATEGDNTEFGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATEGDNTEFGAF
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480
pF1KE3 VGHRDSMDLQRFKETSNKIKILS--------------------NNNTSENTLKRVSSLAG
::::::::::::::::::::::: :::::::::::::::::
XP_005 VGHRDSMDLQRFKETSNKIKILSEQQNDVRNVIMEYTEMPKYENNNTSENTLKRVSSLAG
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KE3 FTDCHRTSIPVHSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTDCHRTSIPVHSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREMPSEEGTLNG
1510 1520 1530 1540 1550 1560
1550 1560 1570 1580 1590 1600
pF1KE3 LTSPFKPAMDTNYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTSPFKPAMDTNYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESSPNILNNSMS
1570 1580 1590 1600 1610 1620
1610 1620 1630 1640 1650 1660
pF1KE3 SWSQLGLCAKIEFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SWSQLGLCAKIEFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFLPEVVNTWSS
1630 1640 1650 1660 1670 1680
1670 1680 1690 1700 1710 1720
pF1KE3 IYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCHSAGQWFAVE
1690 1700 1710 1720 1730 1740
1730 1740 1750 1760 1770 1780
pF1KE3 ECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSV
1750 1760 1770 1780 1790 1800
1790 1800 1810 1820 1830 1840
pF1KE3 IKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTPDKIIFPQDE
1810 1820 1830 1840 1850 1860
1850 1860
pF1KE3 PSDLNLQPGNSTKESESTNSVRLML
:::::::::::::::::::::::::
XP_005 PSDLNLQPGNSTKESESTNSVRLML
1870 1880
>>XP_016877840 (OMIM: 105500,605692) PREDICTED: transien (1893 aa)
initn: 12257 init1: 9766 opt: 9778 Z-score: 10265.3 bits: 1912.7 E(86401): 0
Smith-Waterman score: 12417; 98.9% identity (98.9% similar) in 1884 aa overlap (2-1865:11-1893)
10 20 30 40 50
pF1KE3 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQH
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPPKVLGLQSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 ACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 SYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 LTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 LSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 KTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 ILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 PRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 RFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 DTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 ALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTY
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 ELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAI
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 LLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEME
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 IQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 YIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFAN
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE3 AYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE3 LSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTW
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE3 LTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPP
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE3 LIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE3 GSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTA
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE3 QKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNN
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE3 PFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHG
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE3 VELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATE
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470
pF1KE3 GDNTEFGAFVGHRDSMDLQRFKETSNKIKILS--------------------NNNTSENT
:::::::::::::::::::::::::::::::: ::::::::
XP_016 GDNTEFGAFVGHRDSMDLQRFKETSNKIKILSEQQNDVRNVIMEYTEMPKYENNNTSENT
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KE3 LKRVSSLAGFTDCHRTSIPVHSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREM
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 LKRVSSLAGFTDCHRTSIPVHSKQ-EKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREM
1510 1520 1530 1540 1550
1540 1550 1560 1570 1580 1590
pF1KE3 PSEEGTLNGLTSPFKPAMDTNYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSEEGTLNGLTSPFKPAMDTNYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESS
1560 1570 1580 1590 1600 1610
1600 1610 1620 1630 1640 1650
pF1KE3 PNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFL
1620 1630 1640 1650 1660 1670
1660 1670 1680 1690 1700 1710
pF1KE3 PEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCH
1680 1690 1700 1710 1720 1730
1720 1730 1740 1750 1760 1770
pF1KE3 SAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGV
1740 1750 1760 1770 1780 1790
1780 1790 1800 1810 1820 1830
pF1KE3 GENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTP
1800 1810 1820 1830 1840 1850
1840 1850 1860
pF1KE3 DKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML
::::::::::::::::::::::::::::::::::
XP_016 DKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML
1860 1870 1880 1890
>>XP_016877839 (OMIM: 105500,605692) PREDICTED: transien (1894 aa)
initn: 12470 init1: 9766 opt: 9776 Z-score: 10263.2 bits: 1912.4 E(86401): 0
Smith-Waterman score: 12434; 98.9% identity (98.9% similar) in 1884 aa overlap (2-1865:11-1894)
10 20 30 40 50
pF1KE3 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQH
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPPKVLGLQSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 ACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 SYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 LTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 LSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 KTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 ILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 PRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 RFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 DTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 ALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTY
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 ELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAI
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 LLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEME
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 IQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 YIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFAN
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE3 AYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE3 LSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDVCANDSVIPQICGPGTW
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE3 LTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPPP
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE3 LIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKKLHDFEEQCVEMYFNEKDDKFHS
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE3 GSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLDSQIGHLQDLSALTVDTLKTLTA
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE3 QKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVWKKHGVVNTLSSSLPQGDLESNN
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE3 PFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAGSSSGALFPSAVSPPELRQRLHG
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE3 VELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQPSCKSHLETGTKDQETVCSKATE
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470
pF1KE3 GDNTEFGAFVGHRDSMDLQRFKETSNKIKILS--------------------NNNTSENT
:::::::::::::::::::::::::::::::: ::::::::
XP_016 GDNTEFGAFVGHRDSMDLQRFKETSNKIKILSEQQNDVRNVIMEYTEMPKYENNNTSENT
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KE3 LKRVSSLAGFTDCHRTSIPVHSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKRVSSLAGFTDCHRTSIPVHSKQAEKISRRPSTEDTHEVDSKAALIPDWLQDRPSNREM
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KE3 PSEEGTLNGLTSPFKPAMDTNYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSEEGTLNGLTSPFKPAMDTNYYYSAVERNNLMRLSQSIPFTPVPPRGEPVTVYRLEESS
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KE3 PNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKVQCTWSEHDILKSGHLYIIKSFL
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KE3 PEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFNQMKPKSIPYSPRFLEVFLLYCH
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KE3 SAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGV
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KE3 GENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAKHHCNSCCRKLKLPDLKRNDYTP
1810 1820 1830 1840 1850 1860
1840 1850 1860
pF1KE3 DKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML
::::::::::::::::::::::::::::::::::
XP_016 DKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML
1870 1880 1890
>>XP_016877843 (OMIM: 105500,605692) PREDICTED: transien (1826 aa)
initn: 12047 init1: 9343 opt: 9353 Z-score: 9819.0 bits: 1830.1 E(86401): 0
Smith-Waterman score: 12011; 98.9% identity (98.9% similar) in 1826 aa overlap (60-1865:1-1826)
30 40 50 60 70 80
pF1KE3 LPGCQICQQLVRCFCGRLVKQHACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPT
::::::::::::::::::::::::::::::
XP_016 MKYSDVKLGDHFNQAIEEWSVEKHTEQSPT
10 20 30
90 100 110 120 130 140
pF1KE3 DAYGVINFQGGSHSYRAKYVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAYGVINFQGGSHSYRAKYVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELH
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 PRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGV
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 IENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKT
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 INQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIH
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE3 KQTEEGGNLPDAAEPDIISTIKKTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQTEEGGNLPDAAEPDIISTIKKTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQ
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE3 DIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVM
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE3 DRVAFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVAFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITL
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE3 IDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRA
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE3 DKKEKMRHNHFIKTAQPYRPKIDTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKKEKMRHNHFIKTAQPYRPKIDTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWA
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE3 CLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQL
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE3 AVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMG
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE3 RLNMRKNSWYKVILSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLNMRKNSWYKVILSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEE
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE3 IPMEVFKEVRILDSNEGKNEMEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPMEVFKEVRILDSNEGKNEMEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLML
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE3 YTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDT
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE3 IAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPY
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE3 VMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVY
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE3 AYEIDVCANDSVIPQICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYEIDVCANDSVIPQICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNI
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE3 VWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKK
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE3 LHDFEEQCVEMYFNEKDDKFHSGSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDFEEQCVEMYFNEKDDKFHSGSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLD
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE3 SQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVW
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE3 KKHGVVNTLSSSLPQGDLESNNPFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKHGVVNTLSSSLPQGDLESNNPFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAG
1240 1250 1260 1270 1280 1290
1350 1360 1370 1380 1390 1400
pF1KE3 SSSGALFPSAVSPPELRQRLHGVELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSGALFPSAVSPPELRQRLHGVELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQP
1300 1310 1320 1330 1340 1350
1410 1420 1430 1440 1450 1460
pF1KE3 SCKSHLETGTKDQETVCSKATEGDNTEFGAFVGHRDSMDLQRFKETSNKIKILS------
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCKSHLETGTKDQETVCSKATEGDNTEFGAFVGHRDSMDLQRFKETSNKIKILSEQQNDV
1360 1370 1380 1390 1400 1410
1470 1480 1490 1500
pF1KE3 --------------NNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKISRRPSTEDTH
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNVIMEYTEMPKYENNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKISRRPSTEDTH
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KE3 EVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVERNNLMRLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVERNNLMRLSQS
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KE3 IPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKV
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE3 QCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFN
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KE3 QMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIML
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KE3 AFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAK
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840 1850 1860
pF1KE3 HHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML
1780 1790 1800 1810 1820
>>XP_016877844 (OMIM: 105500,605692) PREDICTED: transien (1826 aa)
initn: 12047 init1: 9343 opt: 9353 Z-score: 9819.0 bits: 1830.1 E(86401): 0
Smith-Waterman score: 12011; 98.9% identity (98.9% similar) in 1826 aa overlap (60-1865:1-1826)
30 40 50 60 70 80
pF1KE3 LPGCQICQQLVRCFCGRLVKQHACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPT
::::::::::::::::::::::::::::::
XP_016 MKYSDVKLGDHFNQAIEEWSVEKHTEQSPT
10 20 30
90 100 110 120 130 140
pF1KE3 DAYGVINFQGGSHSYRAKYVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAYGVINFQGGSHSYRAKYVRLSYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELH
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 PRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRIKQLLGKGLIKAAVTTGAWILTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGV
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 IENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENRNDLVGRDVVAPYQTLLNPLSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKT
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 INQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INQQRIHARIGQGVPVVALIFEGGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIH
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE3 KQTEEGGNLPDAAEPDIISTIKKTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQTEEGGNLPDAAEPDIISTIKKTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQ
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE3 DIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIDVAILTALLKGTNASAFDQLILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVM
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE3 DRVAFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRVAFVKLLIENGVSMHKFLTIPRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITL
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE3 IDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDIGLVIEYLMGGTYRCTYTRKRFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRA
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE3 DKKEKMRHNHFIKTAQPYRPKIDTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKKEKMRHNHFIKTAQPYRPKIDTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWA
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE3 CLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLMKRQVMARFLWQHGEESMAKALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQL
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE3 AVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVELLEQSFRQDETMAMKLLTYELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMG
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE3 RLNMRKNSWYKVILSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLNMRKNSWYKVILSILVPPAILLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEE
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE3 IPMEVFKEVRILDSNEGKNEMEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPMEVFKEVRILDSNEGKNEMEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLML
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE3 YTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTFVVLVQMEQLPSVQEWIVIAYIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDT
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE3 IAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAIISFFIGFGLRFGAKWNFANAYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPY
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE3 VMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMMIGKMVANMFYIVVIMALVLLSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVY
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE3 AYEIDVCANDSVIPQICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYEIDVCANDSVIPQICGPGTWLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNI
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE3 VWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWKYQRYHFIMAYHEKPVLPPPLIILSHIVSLFCCICKRRKKDKTSDGPKLFLTEEDQKK
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE3 LHDFEEQCVEMYFNEKDDKFHSGSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHDFEEQCVEMYFNEKDDKFHSGSEERIRVTFERVEQMCIQIKEVGDRVNYIKRSLQSLD
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE3 SQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQIGHLQDLSALTVDTLKTLTAQKASEASKVHNEITRELSISKHLAQNLIDDGPVRPSVW
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE3 KKHGVVNTLSSSLPQGDLESNNPFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKHGVVNTLSSSLPQGDLESNNPFHCNILMKDDKDPQCNIFGQDLPAVPQRKEFNFPEAG
1240 1250 1260 1270 1280 1290
1350 1360 1370 1380 1390 1400
pF1KE3 SSSGALFPSAVSPPELRQRLHGVELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSGALFPSAVSPPELRQRLHGVELLKIFNKNQKLGSSSTSIPHLSSPPTKFFVSTPSQP
1300 1310 1320 1330 1340 1350
1410 1420 1430 1440 1450 1460
pF1KE3 SCKSHLETGTKDQETVCSKATEGDNTEFGAFVGHRDSMDLQRFKETSNKIKILS------
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCKSHLETGTKDQETVCSKATEGDNTEFGAFVGHRDSMDLQRFKETSNKIKILSEQQNDV
1360 1370 1380 1390 1400 1410
1470 1480 1490 1500
pF1KE3 --------------NNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKISRRPSTEDTH
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNVIMEYTEMPKYENNNTSENTLKRVSSLAGFTDCHRTSIPVHSKQAEKISRRPSTEDTH
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KE3 EVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVERNNLMRLSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVDSKAALIPDWLQDRPSNREMPSEEGTLNGLTSPFKPAMDTNYYYSAVERNNLMRLSQS
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KE3 IPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPFTPVPPRGEPVTVYRLEESSPNILNNSMSSWSQLGLCAKIEFLSKEEMGGGLRRAVKV
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE3 QCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCTWSEHDILKSGHLYIIKSFLPEVVNTWSSIYKEDTVLHLCLREIQQQRAAQKLTFAFN
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KE3 QMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMKPKSIPYSPRFLEVFLLYCHSAGQWFAVEECMTGEFRKYNNNNGDEIIPTNTLEEIML
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KE3 AFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKAEEKRSCDMVFGPANLGEDAIKNFRAK
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840 1850 1860
pF1KE3 HHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHCNSCCRKLKLPDLKRNDYTPDKIIFPQDEPSDLNLQPGNSTKESESTNSVRLML
1780 1790 1800 1810 1820
>>XP_016877845 (OMIM: 105500,605692) PREDICTED: transien (1069 aa)
initn: 7019 init1: 7019 opt: 7021 Z-score: 7372.6 bits: 1376.7 E(86401): 0
Smith-Waterman score: 7021; 99.8% identity (99.9% similar) in 1056 aa overlap (2-1056:11-1066)
10 20 30 40 50
pF1KE3 MSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQH
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPPKVLGLQSQKSWIESTLTKRECVYIIPSSKDPHRCLPGCQICQQLVRCFCGRLVKQH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 ACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACFTASLAMKYSDVKLGDHFNQAIEEWSVEKHTEQSPTDAYGVINFQGGSHSYRAKYVRL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 SYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYDTKPEVILQLLLKEWQMELPKLVISVHGGMQKFELHPRIKQLLGKGLIKAAVTTGAWI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 LTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGGVNTGVAKHVGDALKEHASRSSRKICTIGIAPWGVIENRNDLVGRDVVAPYQTLLNP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 LSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKLNVLNNLHSHFILVDDGTVGKYGAEVRLRRELEKTINQQRIHARIGQGVPVVALIFE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPNVILTVLEYLQESPPVPVVVCEGTGRAADLLAYIHKQTEEGGNLPDAAEPDIISTIK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 KTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTFNFGQNEALHLFQTLMECMKRKELITVFHIGSDEHQDIDVAILTALLKGTNASAFDQL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 ILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILTLAWDRVDIAKNHVFVYGQQWLVGSLEQAMLDALVMDRVAFVKLLIENGVSMHKFLTI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 PRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRLEELYNTKQGPTNPMLFHLVRDVKQGNLPPGYKITLIDIGLVIEYLMGGTYRCTYTRK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 RFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFRLIYNSLGGNNRRSGRNTSSSTPQLRKSHESFGNRADKKEKMRHNHFIKTAQPYRPKI
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 DTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVMEEGKKKRTKDEIVDIDDPETKRFPYPLNELLIWACLMKRQVMARFLWQHGEESMAK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 ALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALVACKIYRSMAYEAKQSDLVDDTSEELKQYSNDFGQLAVELLEQSFRQDETMAMKLLTY
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 ELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKNWSNSTCLKLAVSSRLRPFVAHTCTQMLLSDMWMGRLNMRKNSWYKVILSILVPPAI
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 LLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLEYKTKAEMSHIPQSQDAHQMTMDDSENNFQNITEEIPMEVFKEVRILDSNEGKNEME
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 IQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIVIA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 YIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIFTYAIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFAN
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE3 AYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYDNHVFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVL
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE3 LSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEID-VCANDSVIPQICGPGT
::::::::::::::::::::::::::::::::::::::::::: .:
XP_016 LSFGVPRKAILYPHEAPSWTLAKDIVFHPYWMIFGEVYAYEIDAMCIYK
1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
pF1KE3 WLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLQVKAISNIVWKYQRYHFIMAYHEKPVLPP
1865 residues in 1 query sequences
61573307 residues in 86401 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Mar 10 18:06:26 2017 done: Fri Mar 10 18:06:29 2017
Total Scan time: 16.120 Total Display time: 1.440
Function used was FASTA [36.3.4 Apr, 2011]