Result of FASTA (omim) for
pF1KE3379
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3379, 1130 aa
1>>>pF1KE3379 1130 - 1130 aa - 1130 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8490+/-0.000461; mu= 5.3067+/- 0.028
mean_var=207.7940+/-43.236, 0's: 0 Z-trim(117.0): 116 B-trim: 1148 in 1/50
Lambda= 0.088973
statistics sampled from 28585 (28701) to 28585 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.337), width: 16
Scan time: 18.390
The best scores are: opt bits E(85289)
XP_011520795 (OMIM: 180300,209920,600005) PREDICTE (1130) 7557 984.0 0
NP_000237 (OMIM: 180300,209920,600005) MHC class I (1130) 7557 984.0 0
XP_011520794 (OMIM: 180300,209920,600005) PREDICTE (1131) 7540 981.9 0
NP_001273331 (OMIM: 180300,209920,600005) MHC clas (1131) 7540 981.9 0
XP_011520792 (OMIM: 180300,209920,600005) PREDICTE (1145) 7434 968.3 0
XP_006720943 (OMIM: 180300,209920,600005) PREDICTE (1229) 7422 966.7 0
XP_011520787 (OMIM: 180300,209920,600005) PREDICTE (1229) 7422 966.7 0
XP_011520786 (OMIM: 180300,209920,600005) PREDICTE (1229) 7422 966.7 0
XP_011520790 (OMIM: 180300,209920,600005) PREDICTE (1146) 7417 966.1 0
XP_011520796 (OMIM: 180300,209920,600005) PREDICTE (1107) 7369 959.9 0
XP_011520788 (OMIM: 180300,209920,600005) PREDICTE (1201) 6881 897.3 0
XP_011520793 (OMIM: 180300,209920,600005) PREDICTE (1140) 6710 875.3 0
XP_011520798 (OMIM: 180300,209920,600005) PREDICTE (1081) 6123 800.0 0
XP_011520797 (OMIM: 180300,209920,600005) PREDICTE (1082) 6123 800.0 0
XP_011520791 (OMIM: 180300,209920,600005) PREDICTE (1146) 6123 800.0 0
XP_011520789 (OMIM: 180300,209920,600005) PREDICTE (1147) 6123 800.0 0
NP_001273332 (OMIM: 180300,209920,600005) MHC clas ( 546) 1547 212.4 6.2e-54
NP_001167554 (OMIM: 609364) NACHT, LRR and PYD dom (1039) 397 65.0 2.8e-09
NP_001167553 (OMIM: 609364) NACHT, LRR and PYD dom (1040) 397 65.0 2.8e-09
NP_001167552 (OMIM: 609364) NACHT, LRR and PYD dom (1062) 397 65.0 2.8e-09
NP_060322 (OMIM: 609364) NACHT, LRR and PYD domain (1062) 397 65.0 2.8e-09
XP_011525784 (OMIM: 609648,611762) PREDICTED: NACH ( 948) 391 64.2 4.4e-09
NP_001264058 (OMIM: 609648,611762) NACHT, LRR and (1004) 391 64.2 4.6e-09
XP_011525782 (OMIM: 609648,611762) PREDICTED: NACH (1005) 391 64.2 4.7e-09
NP_996611 (OMIM: 231090,609661) NACHT, LRR and PYD ( 980) 372 61.7 2.5e-08
XP_011524903 (OMIM: 231090,609661) PREDICTED: NACH (1008) 372 61.7 2.5e-08
NP_631915 (OMIM: 231090,609661) NACHT, LRR and PYD (1009) 372 61.7 2.5e-08
XP_011524901 (OMIM: 231090,609661) PREDICTED: NACH (1037) 372 61.7 2.6e-08
XP_006723139 (OMIM: 231090,609661) PREDICTED: NACH (1037) 372 61.7 2.6e-08
XP_006723138 (OMIM: 231090,609661) PREDICTED: NACH (1037) 372 61.7 2.6e-08
NP_001120727 (OMIM: 231090,609661) NACHT, LRR and (1037) 372 61.7 2.6e-08
XP_011524898 (OMIM: 231090,609661) PREDICTED: NACH (1065) 372 61.8 2.6e-08
XP_006721305 (OMIM: 186580,266600,605956,607507,60 ( 985) 371 61.6 2.7e-08
XP_011518233 (OMIM: 609650) PREDICTED: NACHT, LRR ( 703) 357 59.7 7.2e-08
XP_016872742 (OMIM: 609650) PREDICTED: NACHT, LRR ( 730) 357 59.7 7.4e-08
XP_016872741 (OMIM: 609650) PREDICTED: NACHT, LRR ( 771) 357 59.7 7.8e-08
NP_001263629 (OMIM: 609650) NACHT, LRR and PYD dom ( 891) 357 59.8 8.7e-08
NP_612202 (OMIM: 609650) NACHT, LRR and PYD domain ( 892) 357 59.8 8.7e-08
XP_011542355 (OMIM: 120100,191900,606416,607115) P ( 922) 356 59.7 9.8e-08
XP_011542357 (OMIM: 120100,191900,606416,607115) P ( 865) 351 59.0 1.5e-07
XP_016855673 (OMIM: 120100,191900,606416,607115) P ( 922) 351 59.0 1.5e-07
NP_899632 (OMIM: 120100,191900,606416,607115) NACH ( 922) 351 59.0 1.5e-07
NP_001120933 (OMIM: 120100,191900,606416,607115) N ( 979) 351 59.0 1.6e-07
XP_016855672 (OMIM: 120100,191900,606416,607115) P ( 979) 351 59.0 1.6e-07
NP_001120934 (OMIM: 120100,191900,606416,607115) N ( 979) 351 59.0 1.6e-07
NP_001230062 (OMIM: 120100,191900,606416,607115) N (1034) 351 59.0 1.7e-07
NP_004886 (OMIM: 120100,191900,606416,607115) NACH (1036) 351 59.0 1.7e-07
XP_016855671 (OMIM: 120100,191900,606416,607115) P (1036) 351 59.0 1.7e-07
XP_016855670 (OMIM: 120100,191900,606416,607115) P (1036) 351 59.0 1.7e-07
NP_001073289 (OMIM: 120100,191900,606416,607115) N (1036) 351 59.0 1.7e-07
>>XP_011520795 (OMIM: 180300,209920,600005) PREDICTED: M (1130 aa)
initn: 7557 init1: 7557 opt: 7557 Z-score: 5254.1 bits: 984.0 E(85289): 0
Smith-Waterman score: 7557; 99.9% identity (100.0% similar) in 1130 aa overlap (1-1130:1-1130)
10 20 30 40 50 60
pF1KE3 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 HIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVGPVSDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVGPVSDCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 WQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPSM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 VEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLGPQPLVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLGPQPLVAA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 DEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLRG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLRD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 RPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSPPGALAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSPPGALAEL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 AKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGAL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 WLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAAA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 SVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRLSFLGTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRLSFLGTRL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 TPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESLR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 TPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESLQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 QHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 EFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLETL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 NLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDVQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KE3 YNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR
1090 1100 1110 1120 1130
>>NP_000237 (OMIM: 180300,209920,600005) MHC class II tr (1130 aa)
initn: 7557 init1: 7557 opt: 7557 Z-score: 5254.1 bits: 984.0 E(85289): 0
Smith-Waterman score: 7557; 99.9% identity (100.0% similar) in 1130 aa overlap (1-1130:1-1130)
10 20 30 40 50 60
pF1KE3 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 HIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVGPVSDCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVGPVSDCS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 WQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPSM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 VEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVLG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLGPQPLVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLGPQPLVAA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 DEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLRG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 CTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLRD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 RPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSPPGALAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSPPGALAEL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 AKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGAL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 WLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAAA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 SVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRLSFLGTRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRLSFLGTRL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 TPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESLR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_000 TPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESLQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 QHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKKL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 EFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLETL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 NLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDVQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130
pF1KE3 YNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR
1090 1100 1110 1120 1130
>>XP_011520794 (OMIM: 180300,209920,600005) PREDICTED: M (1131 aa)
initn: 7538 init1: 6737 opt: 7540 Z-score: 5242.3 bits: 981.9 E(85289): 0
Smith-Waterman score: 7540; 99.7% identity (99.9% similar) in 1131 aa overlap (1-1130:1-1131)
10 20 30 40 50 60
pF1KE3 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEE
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 EIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIF-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIFI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 KHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVGPVSDC
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVGPVSDC
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 STLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 LWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 MPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 LVEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 GKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLGPQPLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLGPQPLVA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 ADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 GCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 DRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSPPGALAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSPPGALAE
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 LAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 LWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAA
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 ASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRLSFLGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRLSFLGTR
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 LTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESL
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 RQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKK
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE3 LEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLET
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE3 LNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDV
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE3 QYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR
1090 1100 1110 1120 1130
>>NP_001273331 (OMIM: 180300,209920,600005) MHC class II (1131 aa)
initn: 7538 init1: 6737 opt: 7540 Z-score: 5242.3 bits: 981.9 E(85289): 0
Smith-Waterman score: 7540; 99.7% identity (99.9% similar) in 1131 aa overlap (1-1130:1-1131)
10 20 30 40 50 60
pF1KE3 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEE
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 EIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIF-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIFI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 KHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVGPVSDC
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVGPVSDC
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 STLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 LWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 MPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGI
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 LVEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 GKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLGPQPLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLGPQPLVA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 ADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 GCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 DRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSPPGALAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSPPGALAE
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 LAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 LWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAA
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 ASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRLSFLGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRLSFLGTR
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE3 LTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESL
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE3 RQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKK
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE3 LEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLET
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE3 LNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDV
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE3 QYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR
1090 1100 1110 1120 1130
>>XP_011520792 (OMIM: 180300,209920,600005) PREDICTED: M (1145 aa)
initn: 7434 init1: 7434 opt: 7434 Z-score: 5168.7 bits: 968.3 E(85289): 0
Smith-Waterman score: 7434; 99.9% identity (100.0% similar) in 1113 aa overlap (18-1130:33-1145)
10 20 30 40
pF1KE3 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCL
::::::::::::::::::::::::::::::
XP_011 SGRAATDLPRPQSWREGEATSSARGSPGNSGSSQCATMELGPLEGGYLELLNSDADPLCL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 YHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQ
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 DSQLEGLSKDIFKHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSQLEGLSKDIFKHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 TGSLLVGPVSDCSTLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGSLLVGPVSDCSTLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPI
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 QFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGST
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 SPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 TYGAEPAGPDGILVEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYGAEPAGPDGILVEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEH
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 RRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQD
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 LLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRG
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 LLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGM
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 TEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGR
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 AALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELA
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 FPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPA
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 RCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQ
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 ELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRA
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 ALSDTVALWESLRQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDT
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALSDTVALWESLQQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDT
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 AGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQL
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 SATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARV
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 LPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRI
1090 1100 1110 1120 1130 1140
1130
pF1KE3 SLR
:::
XP_011 SLR
>>XP_006720943 (OMIM: 180300,209920,600005) PREDICTED: M (1229 aa)
initn: 7418 init1: 6737 opt: 7422 Z-score: 5159.9 bits: 966.7 E(85289): 0
Smith-Waterman score: 7422; 98.8% identity (99.0% similar) in 1131 aa overlap (4-1130:100-1229)
10 20 30
pF1KE3 MRCLAPRPA---GSYLSEPQGSSQCATMELGPL
: : :: : :. :::::::::::::
XP_006 DSEALARKISLTLLEKGDLDLALLGWARSGLQP-PAAERGPGHSDHGGSSQCATMELGPL
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE3 EGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEE
130 140 150 160 170 180
100 110 120 130 140
pF1KE3 TREAYANIAELDQYVFQDSQLEGLSKDIF-KHIGPDEVIGESMEMPAEVGQKSQKRPFPE
::::::::::::::::::::::::::::: .:::::::::::::::::::::::::::::
XP_006 TREAYANIAELDQYVFQDSQLEGLSKDIFIEHIGPDEVIGESMEMPAEVGQKSQKRPFPE
190 200 210 220 230 240
150 160 170 180 190 200
pF1KE3 ELPADLKHWKPAEPPTVVTGSLLVGPVSDCSTLPCLPLPALFNQEPASGQMRLEKTDQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELPADLKHWKPAEPPTVVTGSLLVGPVSDCSTLPCLPLPALFNQEPASGQMRLEKTDQIP
250 260 270 280 290 300
210 220 230 240 250 260
pF1KE3 MPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPP
310 320 330 340 350 360
270 280 290 300 310 320
pF1KE3 SGFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSN
370 380 390 400 410 420
330 340 350 360 370 380
pF1KE3 KLPKWPEPVEQFYRSLQDTYGAEPAGPDGILVEVDLVQARLERSSSKSLERELATPDWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLPKWPEPVEQFYRSLQDTYGAEPAGPDGILVEVDLVQARLERSSSKSLERELATPDWAE
430 440 450 460 470 480
390 400 410 420 430 440
pF1KE3 RQLAQGGLAEVLLAAKEHRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQLAQGGLAEVLLAAKEHRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVF
490 500 510 520 530 540
450 460 470 480 490 500
pF1KE3 SVPCHCLNRPGDAYGLQDLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVPCHCLNRPGDAYGLQDLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDG
550 560 570 580 590 600
510 520 530 540 550 560
pF1KE3 FLHSTCGPAPAEPCSLRGLLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLHSTCGPAPAEPCSLRGLLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGF
610 620 630 640 650 660
570 580 590 600 610 620
pF1KE3 SMEQAQAYVMRYFESSGMTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SMEQAQAYVMRYFESSGMTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGE
670 680 690 700 710 720
630 640 650 660 670 680
pF1KE3 DAKLPSTLTGLYVGLLGRAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DAKLPSTLTGLYVGLLGRAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWA
730 740 750 760 770 780
690 700 710 720 730 740
pF1KE3 MAKGLVQHPPRAAESELAFPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAKGLVQHPPRAAESELAFPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDN
790 800 810 820 830 840
750 760 770 780 790 800
pF1KE3 WLEGVPRFLAGLIFQPPARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WLEGVPRFLAGLIFQPPARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLEL
850 860 870 880 890 900
810 820 830 840 850 860
pF1KE3 LHCAHEAEEAGIWQHVVQELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LHCAHEAEEAGIWQHVVQELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGIC
910 920 930 940 950 960
870 880 890 900 910 920
pF1KE3 PSGLGSLVGLSCVTRFRAALSDTVALWESLRQHGETKLLQAAEEKFTIEPFKAKSLKDVE
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_006 PSGLGSLVGLSCVTRFRAALSDTVALWESLQQHGETKLLQAAEEKFTIEPFKAKSLKDVE
970 980 990 1000 1010 1020
930 940 950 960 970 980
pF1KE3 DLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHL
1030 1040 1050 1060 1070 1080
990 1000 1010 1020 1030 1040
pF1KE3 DLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRL
1090 1100 1110 1120 1130 1140
1050 1060 1070 1080 1090 1100
pF1KE3 SLYNNCICDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLYNNCICDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWT
1150 1160 1170 1180 1190 1200
1110 1120 1130
pF1KE3 PTIPFSVQEHLQQQDSRISLR
:::::::::::::::::::::
XP_006 PTIPFSVQEHLQQQDSRISLR
1210 1220
>>XP_011520787 (OMIM: 180300,209920,600005) PREDICTED: M (1229 aa)
initn: 7418 init1: 6737 opt: 7422 Z-score: 5159.9 bits: 966.7 E(85289): 0
Smith-Waterman score: 7422; 98.8% identity (99.0% similar) in 1131 aa overlap (4-1130:100-1229)
10 20 30
pF1KE3 MRCLAPRPA---GSYLSEPQGSSQCATMELGPL
: : :: : :. :::::::::::::
XP_011 DSEALARKISLTLLEKGDLDLALLGWARSGLQP-PAAERGPGHSDHGGSSQCATMELGPL
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE3 EGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEE
130 140 150 160 170 180
100 110 120 130 140
pF1KE3 TREAYANIAELDQYVFQDSQLEGLSKDIF-KHIGPDEVIGESMEMPAEVGQKSQKRPFPE
::::::::::::::::::::::::::::: .:::::::::::::::::::::::::::::
XP_011 TREAYANIAELDQYVFQDSQLEGLSKDIFIEHIGPDEVIGESMEMPAEVGQKSQKRPFPE
190 200 210 220 230 240
150 160 170 180 190 200
pF1KE3 ELPADLKHWKPAEPPTVVTGSLLVGPVSDCSTLPCLPLPALFNQEPASGQMRLEKTDQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELPADLKHWKPAEPPTVVTGSLLVGPVSDCSTLPCLPLPALFNQEPASGQMRLEKTDQIP
250 260 270 280 290 300
210 220 230 240 250 260
pF1KE3 MPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPP
310 320 330 340 350 360
270 280 290 300 310 320
pF1KE3 SGFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSN
370 380 390 400 410 420
330 340 350 360 370 380
pF1KE3 KLPKWPEPVEQFYRSLQDTYGAEPAGPDGILVEVDLVQARLERSSSKSLERELATPDWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLPKWPEPVEQFYRSLQDTYGAEPAGPDGILVEVDLVQARLERSSSKSLERELATPDWAE
430 440 450 460 470 480
390 400 410 420 430 440
pF1KE3 RQLAQGGLAEVLLAAKEHRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQLAQGGLAEVLLAAKEHRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVF
490 500 510 520 530 540
450 460 470 480 490 500
pF1KE3 SVPCHCLNRPGDAYGLQDLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVPCHCLNRPGDAYGLQDLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDG
550 560 570 580 590 600
510 520 530 540 550 560
pF1KE3 FLHSTCGPAPAEPCSLRGLLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLHSTCGPAPAEPCSLRGLLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGF
610 620 630 640 650 660
570 580 590 600 610 620
pF1KE3 SMEQAQAYVMRYFESSGMTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEQAQAYVMRYFESSGMTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGE
670 680 690 700 710 720
630 640 650 660 670 680
pF1KE3 DAKLPSTLTGLYVGLLGRAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAKLPSTLTGLYVGLLGRAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWA
730 740 750 760 770 780
690 700 710 720 730 740
pF1KE3 MAKGLVQHPPRAAESELAFPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKGLVQHPPRAAESELAFPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDN
790 800 810 820 830 840
750 760 770 780 790 800
pF1KE3 WLEGVPRFLAGLIFQPPARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLEGVPRFLAGLIFQPPARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLEL
850 860 870 880 890 900
810 820 830 840 850 860
pF1KE3 LHCAHEAEEAGIWQHVVQELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHCAHEAEEAGIWQHVVQELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGIC
910 920 930 940 950 960
870 880 890 900 910 920
pF1KE3 PSGLGSLVGLSCVTRFRAALSDTVALWESLRQHGETKLLQAAEEKFTIEPFKAKSLKDVE
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_011 PSGLGSLVGLSCVTRFRAALSDTVALWESLQQHGETKLLQAAEEKFTIEPFKAKSLKDVE
970 980 990 1000 1010 1020
930 940 950 960 970 980
pF1KE3 DLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHL
1030 1040 1050 1060 1070 1080
990 1000 1010 1020 1030 1040
pF1KE3 DLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRL
1090 1100 1110 1120 1130 1140
1050 1060 1070 1080 1090 1100
pF1KE3 SLYNNCICDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLYNNCICDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWT
1150 1160 1170 1180 1190 1200
1110 1120 1130
pF1KE3 PTIPFSVQEHLQQQDSRISLR
:::::::::::::::::::::
XP_011 PTIPFSVQEHLQQQDSRISLR
1210 1220
>>XP_011520786 (OMIM: 180300,209920,600005) PREDICTED: M (1229 aa)
initn: 7418 init1: 6737 opt: 7422 Z-score: 5159.9 bits: 966.7 E(85289): 0
Smith-Waterman score: 7422; 98.8% identity (99.0% similar) in 1131 aa overlap (4-1130:100-1229)
10 20 30
pF1KE3 MRCLAPRPA---GSYLSEPQGSSQCATMELGPL
: : :: : :. :::::::::::::
XP_011 DSEALARKISLTLLEKGDLDLALLGWARSGLQP-PAAERGPGHSDHGGSSQCATMELGPL
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE3 EGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGYLELLNSDADPLCLYHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEE
130 140 150 160 170 180
100 110 120 130 140
pF1KE3 TREAYANIAELDQYVFQDSQLEGLSKDIF-KHIGPDEVIGESMEMPAEVGQKSQKRPFPE
::::::::::::::::::::::::::::: .:::::::::::::::::::::::::::::
XP_011 TREAYANIAELDQYVFQDSQLEGLSKDIFIEHIGPDEVIGESMEMPAEVGQKSQKRPFPE
190 200 210 220 230 240
150 160 170 180 190 200
pF1KE3 ELPADLKHWKPAEPPTVVTGSLLVGPVSDCSTLPCLPLPALFNQEPASGQMRLEKTDQIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELPADLKHWKPAEPPTVVTGSLLVGPVSDCSTLPCLPLPALFNQEPASGQMRLEKTDQIP
250 260 270 280 290 300
210 220 230 240 250 260
pF1KE3 MPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPFSSSSLSCLNLPEGPIQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPP
310 320 330 340 350 360
270 280 290 300 310 320
pF1KE3 SGFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGFTVHGLPTSPDRPGSTSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSN
370 380 390 400 410 420
330 340 350 360 370 380
pF1KE3 KLPKWPEPVEQFYRSLQDTYGAEPAGPDGILVEVDLVQARLERSSSKSLERELATPDWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLPKWPEPVEQFYRSLQDTYGAEPAGPDGILVEVDLVQARLERSSSKSLERELATPDWAE
430 440 450 460 470 480
390 400 410 420 430 440
pF1KE3 RQLAQGGLAEVLLAAKEHRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQLAQGGLAEVLLAAKEHRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVF
490 500 510 520 530 540
450 460 470 480 490 500
pF1KE3 SVPCHCLNRPGDAYGLQDLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVPCHCLNRPGDAYGLQDLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDG
550 560 570 580 590 600
510 520 530 540 550 560
pF1KE3 FLHSTCGPAPAEPCSLRGLLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLHSTCGPAPAEPCSLRGLLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGF
610 620 630 640 650 660
570 580 590 600 610 620
pF1KE3 SMEQAQAYVMRYFESSGMTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEQAQAYVMRYFESSGMTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGE
670 680 690 700 710 720
630 640 650 660 670 680
pF1KE3 DAKLPSTLTGLYVGLLGRAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAKLPSTLTGLYVGLLGRAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWA
730 740 750 760 770 780
690 700 710 720 730 740
pF1KE3 MAKGLVQHPPRAAESELAFPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKGLVQHPPRAAESELAFPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDN
790 800 810 820 830 840
750 760 770 780 790 800
pF1KE3 WLEGVPRFLAGLIFQPPARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLEGVPRFLAGLIFQPPARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLEL
850 860 870 880 890 900
810 820 830 840 850 860
pF1KE3 LHCAHEAEEAGIWQHVVQELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHCAHEAEEAGIWQHVVQELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGIC
910 920 930 940 950 960
870 880 890 900 910 920
pF1KE3 PSGLGSLVGLSCVTRFRAALSDTVALWESLRQHGETKLLQAAEEKFTIEPFKAKSLKDVE
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_011 PSGLGSLVGLSCVTRFRAALSDTVALWESLQQHGETKLLQAAEEKFTIEPFKAKSLKDVE
970 980 990 1000 1010 1020
930 940 950 960 970 980
pF1KE3 DLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLGKLVQTQRTRSSSEDTAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHL
1030 1040 1050 1060 1070 1080
990 1000 1010 1020 1030 1040
pF1KE3 DLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLDALSENKIGDEGVSQLSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRL
1090 1100 1110 1120 1130 1140
1050 1060 1070 1080 1090 1100
pF1KE3 SLYNNCICDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLYNNCICDVGAESLARVLPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWT
1150 1160 1170 1180 1190 1200
1110 1120 1130
pF1KE3 PTIPFSVQEHLQQQDSRISLR
:::::::::::::::::::::
XP_011 PTIPFSVQEHLQQQDSRISLR
1210 1220
>>XP_011520790 (OMIM: 180300,209920,600005) PREDICTED: M (1146 aa)
initn: 7415 init1: 6737 opt: 7417 Z-score: 5156.9 bits: 966.1 E(85289): 0
Smith-Waterman score: 7417; 99.7% identity (99.9% similar) in 1114 aa overlap (18-1130:33-1146)
10 20 30 40
pF1KE3 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCL
::::::::::::::::::::::::::::::
XP_011 SGRAATDLPRPQSWREGEATSSARGSPGNSGSSQCATMELGPLEGGYLELLNSDADPLCL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 YHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHFYDQMDLAGEEEIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQ
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 DSQLEGLSKDIF-KHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTV
:::::::::::: .::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSQLEGLSKDIFIEHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTV
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 VTGSLLVGPVSDCSTLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTGSLLVGPVSDCSTLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGP
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 IQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQFVPTISTLPHGLWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGS
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 TSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSPFAPSATDLPSMPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQ
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 DTYGAEPAGPDGILVEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTYGAEPAGPDGILVEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKE
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 HRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRRPRETRVIAVLGKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQ
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 DLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLFSLGPQPLVAADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLR
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 GLLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLAGLFQKKLLRGCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSG
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 MTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTEHQDRALTLLRDRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLG
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 RAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAALDSPPGALAELAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESEL
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 AFPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFPSFLLQCFLGALWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPP
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 ARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARCLGALLGPSAAASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVV
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 QELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QELPGRLSFLGTRLTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 AALSDTVALWESLRQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSED
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALSDTVALWESLQQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSED
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 TAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGELPAVRDLKKLEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQ
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 LSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSATFPQLKSLETLNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLAR
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 VLPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLPDMVSLRVMDVQYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSR
1090 1100 1110 1120 1130 1140
1130
pF1KE3 ISLR
::::
XP_011 ISLR
>>XP_011520796 (OMIM: 180300,209920,600005) PREDICTED: M (1107 aa)
initn: 7367 init1: 6737 opt: 7369 Z-score: 5123.8 bits: 959.9 E(85289): 0
Smith-Waterman score: 7369; 99.7% identity (99.9% similar) in 1107 aa overlap (25-1130:1-1107)
10 20 30 40 50 60
pF1KE3 MRCLAPRPAGSYLSEPQGSSQCATMELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEE
::::::::::::::::::::::::::::::::::::
XP_011 MELGPLEGGYLELLNSDADPLCLYHFYDQMDLAGEE
10 20 30
70 80 90 100 110
pF1KE3 EIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIF-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIELYSEPDTDTINCDQFSRLLCDMEGDEETREAYANIAELDQYVFQDSQLEGLSKDIFI
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE3 KHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVGPVSDC
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHIGPDEVIGESMEMPAEVGQKSQKRPFPEELPADLKHWKPAEPPTVVTGSLLVGPVSDC
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE3 STLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STLPCLPLPALFNQEPASGQMRLEKTDQIPMPFSSSSLSCLNLPEGPIQFVPTISTLPHG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE3 LWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWQISEAGTGVSSIFIYHGEVPQASQVPPPSGFTVHGLPTSPDRPGSTSPFAPSATDLPS
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE3 MPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPEPALTSRANMTEHKTSPTQCPAAGEVSNKLPKWPEPVEQFYRSLQDTYGAEPAGPDGI
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE3 LVEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEVDLVQARLERSSSKSLERELATPDWAERQLAQGGLAEVLLAAKEHRRPRETRVIAVL
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE3 GKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLGPQPLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKAGQGKSYWAGAVSRAWACGRLPQYDFVFSVPCHCLNRPGDAYGLQDLLFSLGPQPLVA
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE3 ADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADEVFSHILKRPDRVLLILDGFEELEAQDGFLHSTCGPAPAEPCSLRGLLAGLFQKKLLR
460 470 480 490 500 510
540 550 560 570 580 590
pF1KE3 GCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCTLLLTARPRGRLVQSLSKADALFELSGFSMEQAQAYVMRYFESSGMTEHQDRALTLLR
520 530 540 550 560 570
600 610 620 630 640 650
pF1KE3 DRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSPPGALAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRPLLLSHSHSPTLCRAVCQLSEALLELGEDAKLPSTLTGLYVGLLGRAALDSPPGALAE
580 590 600 610 620 630
660 670 680 690 700 710
pF1KE3 LAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKLAWELGRRHQSTLQEDQFPSADVRTWAMAKGLVQHPPRAAESELAFPSFLLQCFLGA
640 650 660 670 680 690
720 730 740 750 760 770
pF1KE3 LWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWLALSGEIKDKELPQYLALTPRKKRPYDNWLEGVPRFLAGLIFQPPARCLGALLGPSAA
700 710 720 730 740 750
780 790 800 810 820 830
pF1KE3 ASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRLSFLGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASVDRKQKVLARYLKRLQPGTLRARQLLELLHCAHEAEEAGIWQHVVQELPGRLSFLGTR
760 770 780 790 800 810
840 850 860 870 880 890
pF1KE3 LTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTPPDAHVLGKALEAAGQDFSLDLRSTGICPSGLGSLVGLSCVTRFRAALSDTVALWESL
820 830 840 850 860 870
900 910 920 930 940 950
pF1KE3 RQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKK
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQHGETKLLQAAEEKFTIEPFKAKSLKDVEDLGKLVQTQRTRSSSEDTAGELPAVRDLKK
880 890 900 910 920 930
960 970 980 990 1000 1010
pF1KE3 LEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEFALGPVSGPQAFPKLVRILTAFSSLQHLDLDALSENKIGDEGVSQLSATFPQLKSLET
940 950 960 970 980 990
1020 1030 1040 1050 1060 1070
pF1KE3 LNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNLSQNNITDLGAYKLAEALPSLAASLLRLSLYNNCICDVGAESLARVLPDMVSLRVMDV
1000 1010 1020 1030 1040 1050
1080 1090 1100 1110 1120 1130
pF1KE3 QYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYNKFTAAGAQQLAASLRRCPHVETLAMWTPTIPFSVQEHLQQQDSRISLR
1060 1070 1080 1090 1100
1130 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:07:48 2016 done: Sun Nov 6 14:07:51 2016
Total Scan time: 18.390 Total Display time: 0.650
Function used was FASTA [36.3.4 Apr, 2011]