Result of FASTA (omim) for
pF1KE3374
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3374, 1117 aa
1>>>pF1KE3374 1117 - 1117 aa - 1117 aa
Library: /omim/omim.rfq.tfa
64369986 residues in 92320 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4148+/-0.000349; mu= 4.8803+/- 0.022
mean_var=291.1349+/-64.117, 0's: 0 Z-trim(122.1): 112 B-trim: 664 in 2/52
Lambda= 0.075167
statistics sampled from 41071 (41186) to 41071 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.446), width: 16
Scan time: 8.870
The best scores are: opt bits E(92320)
NP_001099010 (OMIM: 601441) diacylglycerol kinase (1117) 7695 849.0 0
XP_016873945 (OMIM: 601441) diacylglycerol kinase (1175) 7695 849.0 0
XP_016873944 (OMIM: 601441) diacylglycerol kinase (1176) 7683 847.7 0
NP_963290 (OMIM: 601441) diacylglycerol kinase zet ( 945) 6048 670.3 1.6e-191
NP_001186196 (OMIM: 601441) diacylglycerol kinase ( 928) 6047 670.2 1.7e-191
XP_005253239 (OMIM: 601441) diacylglycerol kinase ( 934) 6041 669.6 2.6e-191
NP_003637 (OMIM: 601441) diacylglycerol kinase zet ( 929) 6035 668.9 4.1e-191
NP_963291 (OMIM: 601441) diacylglycerol kinase zet ( 933) 6023 667.6 1e-190
NP_001186195 (OMIM: 601441) diacylglycerol kinase ( 934) 6015 666.8 1.9e-190
NP_001186197 (OMIM: 601441) diacylglycerol kinase ( 906) 5072 564.5 1.1e-159
XP_024304498 (OMIM: 601441) diacylglycerol kinase (1208) 4849 540.4 2.6e-152
XP_024304508 (OMIM: 601441) diacylglycerol kinase ( 845) 4260 476.4 3.4e-133
NP_001308637 (OMIM: 604072) diacylglycerol kinase (1057) 3455 389.2 7.5e-107
NP_004708 (OMIM: 604072) diacylglycerol kinase iot (1065) 3332 375.9 7.8e-103
XP_024304504 (OMIM: 601441) diacylglycerol kinase ( 966) 3207 362.3 8.8e-99
XP_024304502 (OMIM: 601441) diacylglycerol kinase ( 978) 3202 361.7 1.3e-98
XP_024304506 (OMIM: 601441) diacylglycerol kinase ( 961) 3201 361.6 1.4e-98
XP_016868269 (OMIM: 604072) diacylglycerol kinase (1078) 3179 359.3 7.8e-98
XP_024304509 (OMIM: 601441) diacylglycerol kinase ( 842) 2872 325.9 6.9e-88
XP_024304507 (OMIM: 601441) diacylglycerol kinase ( 944) 2872 325.9 7.5e-88
XP_024304505 (OMIM: 601441) diacylglycerol kinase ( 962) 2872 325.9 7.6e-88
XP_024304503 (OMIM: 601441) diacylglycerol kinase ( 967) 2872 325.9 7.6e-88
XP_024304501 (OMIM: 601441) diacylglycerol kinase ( 979) 2872 325.9 7.7e-88
XP_024304500 (OMIM: 601441) diacylglycerol kinase (1151) 2872 326.0 8.6e-88
XP_024304499 (OMIM: 601441) diacylglycerol kinase (1186) 2872 326.0 8.8e-88
XP_024304497 (OMIM: 601441) diacylglycerol kinase (1209) 2872 326.0 8.9e-88
NP_001308638 (OMIM: 604072) diacylglycerol kinase ( 757) 2582 294.4 1.9e-78
XP_016868277 (OMIM: 604072) diacylglycerol kinase ( 757) 2582 294.4 1.9e-78
NP_001308639 (OMIM: 604072) diacylglycerol kinase ( 734) 2459 281.0 1.9e-74
NP_001337653 (OMIM: 604070) diacylglycerol kinase ( 754) 852 106.8 5.6e-22
NP_001337640 (OMIM: 604070) diacylglycerol kinase ( 796) 852 106.8 5.8e-22
NP_001337641 (OMIM: 604070) diacylglycerol kinase ( 796) 852 106.8 5.8e-22
NP_001337643 (OMIM: 604070) diacylglycerol kinase ( 796) 852 106.8 5.8e-22
NP_001337638 (OMIM: 604070) diacylglycerol kinase ( 803) 852 106.8 5.8e-22
NP_001337637 (OMIM: 604070) diacylglycerol kinase ( 803) 852 106.8 5.8e-22
NP_001337636 (OMIM: 604070) diacylglycerol kinase ( 803) 852 106.8 5.8e-22
XP_016867279 (OMIM: 604070) diacylglycerol kinase ( 725) 850 106.5 6.3e-22
NP_001337652 (OMIM: 604070) diacylglycerol kinase ( 762) 850 106.6 6.5e-22
NP_001337651 (OMIM: 604070) diacylglycerol kinase ( 762) 850 106.6 6.5e-22
NP_663733 (OMIM: 604070) diacylglycerol kinase bet ( 773) 850 106.6 6.6e-22
NP_001337650 (OMIM: 604070) diacylglycerol kinase ( 785) 850 106.6 6.7e-22
NP_001337649 (OMIM: 604070) diacylglycerol kinase ( 785) 850 106.6 6.7e-22
NP_001337648 (OMIM: 604070) diacylglycerol kinase ( 792) 850 106.6 6.7e-22
NP_001337646 (OMIM: 604070) diacylglycerol kinase ( 792) 850 106.6 6.7e-22
NP_001337647 (OMIM: 604070) diacylglycerol kinase ( 792) 850 106.6 6.7e-22
NP_001337644 (OMIM: 604070) diacylglycerol kinase ( 797) 850 106.6 6.7e-22
NP_001337645 (OMIM: 604070) diacylglycerol kinase ( 797) 850 106.6 6.7e-22
XP_011513456 (OMIM: 604070) diacylglycerol kinase ( 804) 850 106.6 6.8e-22
NP_001337634 (OMIM: 604070) diacylglycerol kinase ( 804) 850 106.6 6.8e-22
NP_001337635 (OMIM: 604070) diacylglycerol kinase ( 804) 850 106.6 6.8e-22
>>NP_001099010 (OMIM: 601441) diacylglycerol kinase zeta (1117 aa)
initn: 7695 init1: 7695 opt: 7695 Z-score: 4524.6 bits: 849.0 E(92320): 0
Smith-Waterman score: 7695; 100.0% identity (100.0% similar) in 1117 aa overlap (1-1117:1-1117)
10 20 30 40 50 60
pF1KE3 METFFRRHFRGKVPGPGEGQQRPSSVGLPTGKARRRSPAGQASSSLAQRRRSSAQLQGCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METFFRRHFRGKVPGPGEGQQRPSSVGLPTGKARRRSPAGQASSSLAQRRRSSAQLQGCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LSCGVRAQGSSRRRSSTVPPSCNPRFIVDKVLTPQPTTVGAQLLGAPLLLTGLVGMNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSCGVRAQGSSRRRSSTVPPSCNPRFIVDKVLTPQPTTVGAQLLGAPLLLTGLVGMNEEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GVQEDVVAEASSAIQPGTKTPGPPPPRGAQPLLPLPRYLRRASSHLLPADAVYDHALWGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVQEDVVAEASSAIQPGTKTPGPPPPRGAQPLLPLPRYLRRASSHLLPADAVYDHALWGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 HGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTRVRPLSRRRQVALRRKAAGPQAWSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTRVRPLSRRRQVALRRKAAGPQAWSA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 HHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 LGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILAC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 NVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 EKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 RYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 SKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 SMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 SPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 TSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 STGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQG
1030 1040 1050 1060 1070 1080
1090 1100 1110
pF1KE3 DTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
:::::::::::::::::::::::::::::::::::::
NP_001 DTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
1090 1100 1110
>>XP_016873945 (OMIM: 601441) diacylglycerol kinase zeta (1175 aa)
initn: 7695 init1: 7695 opt: 7695 Z-score: 4524.3 bits: 849.0 E(92320): 0
Smith-Waterman score: 7695; 100.0% identity (100.0% similar) in 1117 aa overlap (1-1117:59-1175)
10 20 30
pF1KE3 METFFRRHFRGKVPGPGEGQQRPSSVGLPT
::::::::::::::::::::::::::::::
XP_016 AGPEPDKAPRRLNKRRFPGLRLFGHSQPPAMETFFRRHFRGKVPGPGEGQQRPSSVGLPT
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 GKARRRSPAGQASSSLAQRRRSSAQLQGCLLSCGVRAQGSSRRRSSTVPPSCNPRFIVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKARRRSPAGQASSSLAQRRRSSAQLQGCLLSCGVRAQGSSRRRSSTVPPSCNPRFIVDK
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 VLTPQPTTVGAQLLGAPLLLTGLVGMNEEEGVQEDVVAEASSAIQPGTKTPGPPPPRGAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTPQPTTVGAQLLGAPLLLTGLVGMNEEEGVQEDVVAEASSAIQPGTKTPGPPPPRGAQ
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 PLLPLPRYLRRASSHLLPADAVYDHALWGLHGYYRRLSQRRPSGQHPGPGGRRASGTTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLPLPRYLRRASSHLLPADAVYDHALWGLHGYYRRLSQRRPSGQHPGPGGRRASGTTAG
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE3 TMLPTRVRPLSRRRQVALRRKAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMLPTRVRPLSRRRQVALRRKAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESER
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE3 QIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLKSVSRRKCAACKIVVHTPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLKSVSRRKCAACKIVVHTPC
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE3 IEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKE
390 400 410 420 430 440
400 410 420 430 440 450
pF1KE3 IVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKK
450 460 470 480 490 500
460 470 480 490 500 510
pF1KE3 KRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLN
510 520 530 540 550 560
520 530 540 550 560 570
pF1KE3 PRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLG
570 580 590 600 610 620
580 590 600 610 620 630
pF1KE3 TGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDR
630 640 650 660 670 680
640 650 660 670 680 690
pF1KE3 LPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLA
690 700 710 720 730 740
700 710 720 730 740 750
pF1KE3 KHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEV
750 760 770 780 790 800
760 770 780 790 800 810
pF1KE3 IGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATM
810 820 830 840 850 860
820 830 840 850 860 870
pF1KE3 VQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGD
870 880 890 900 910 920
880 890 900 910 920 930
pF1KE3 SDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTE
930 940 950 960 970 980
940 950 960 970 980 990
pF1KE3 IAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRN
990 1000 1010 1020 1030 1040
1000 1010 1020 1030 1040 1050
pF1KE3 DFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETC
1050 1060 1070 1080 1090 1100
1060 1070 1080 1090 1100 1110
pF1KE3 LHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQR
1110 1120 1130 1140 1150 1160
pF1KE3 EDQETAV
:::::::
XP_016 EDQETAV
1170
>>XP_016873944 (OMIM: 601441) diacylglycerol kinase zeta (1176 aa)
initn: 5558 init1: 5558 opt: 7683 Z-score: 4517.2 bits: 847.7 E(92320): 0
Smith-Waterman score: 7683; 99.9% identity (99.9% similar) in 1118 aa overlap (1-1117:59-1176)
10 20 30
pF1KE3 METFFRRHFRGKVPGPGEGQQRPSSVGLPT
::::::::::::::::::::::::::::::
XP_016 AGPEPDKAPRRLNKRRFPGLRLFGHSQPPAMETFFRRHFRGKVPGPGEGQQRPSSVGLPT
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 GKARRRSPAGQASSSLAQRRRSSAQLQGCLLSCGVRAQGSSRRRSSTVPPSCNPRFIVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKARRRSPAGQASSSLAQRRRSSAQLQGCLLSCGVRAQGSSRRRSSTVPPSCNPRFIVDK
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 VLTPQPTTVGAQLLGAPLLLTGLVGMNEEEGVQEDVVAEASSAIQPGTKTPGPPPPRGAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLTPQPTTVGAQLLGAPLLLTGLVGMNEEEGVQEDVVAEASSAIQPGTKTPGPPPPRGAQ
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 PLLPLPRYLRRASSHLLPADAVYDHALWGLHGYYRRLSQRRPSGQHPGPGGRRASGTTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLPLPRYLRRASSHLLPADAVYDHALWGLHGYYRRLSQRRPSGQHPGPGGRRASGTTAG
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE3 TMLPTRVRPLSRRRQVALRRKAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMLPTRVRPLSRRRQVALRRKAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESER
270 280 290 300 310 320
280 290 300 310 320
pF1KE3 QIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARML-KSVSRRKCAACKIVVHTP
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_016 QIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRKCAACKIVVHTP
330 340 350 360 370 380
330 340 350 360 370 380
pF1KE3 CIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSK
390 400 410 420 430 440
390 400 410 420 430 440
pF1KE3 EIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKK
450 460 470 480 490 500
450 460 470 480 490 500
pF1KE3 KKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYL
510 520 530 540 550 560
510 520 530 540 550 560
pF1KE3 NPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPL
570 580 590 600 610 620
570 580 590 600 610 620
pF1KE3 GTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATD
630 640 650 660 670 680
630 640 650 660 670 680
pF1KE3 RLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDL
690 700 710 720 730 740
690 700 710 720 730 740
pF1KE3 AKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLE
750 760 770 780 790 800
750 760 770 780 790 800
pF1KE3 VIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQAT
810 820 830 840 850 860
810 820 830 840 850 860
pF1KE3 MVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPG
870 880 890 900 910 920
870 880 890 900 910 920
pF1KE3 DSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVT
930 940 950 960 970 980
930 940 950 960 970 980
pF1KE3 EIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKR
990 1000 1010 1020 1030 1040
990 1000 1010 1020 1030 1040
pF1KE3 NDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGET
1050 1060 1070 1080 1090 1100
1050 1060 1070 1080 1090 1100
pF1KE3 CLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQ
1110 1120 1130 1140 1150 1160
1110
pF1KE3 REDQETAV
::::::::
XP_016 REDQETAV
1170
>>NP_963290 (OMIM: 601441) diacylglycerol kinase zeta is (945 aa)
initn: 6041 init1: 6041 opt: 6048 Z-score: 3560.2 bits: 670.3 E(92320): 1.6e-191
Smith-Waterman score: 6087; 95.5% identity (96.3% similar) in 935 aa overlap (185-1117:27-945)
160 170 180 190 200 210
pF1KE3 LPRYLRRASSHLLPADAVYDHALWGLHGYYRRLSQRRPSGQ--HPGPGGRRASGTTAGTM
:: .: .: .: : : : ::.::
NP_963 MAEGQGGGGQRWDWAGGGRAAEEEVVRRRCRRGEEAQVAQPWPEGSR--GTAAGPP
10 20 30 40 50
220 230 240 250 260 270
pF1KE3 LPTRVRPLSRRRQVALRRKAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESERQI
. : : : :.::. : :::::::::::::::::::::::::::::
NP_963 VEERFRQLHLRKQVSYR--------------KAITKSGLQHLAPPPPTPGAPCSESERQI
60 70 80 90 100
280 290 300 310 320 330
pF1KE3 RSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLKSVSRRKCAACKIVVHTPCIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 RSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLKSVSRRKCAACKIVVHTPCIE
110 120 130 140 150 160
340 350 360 370 380 390
pF1KE3 QLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIV
170 180 190 200 210 220
400 410 420 430 440 450
pF1KE3 AISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 AISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKR
230 240 250 260 270 280
460 470 480 490 500 510
pF1KE3 ASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 ASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPR
290 300 310 320 330 340
520 530 540 550 560 570
pF1KE3 QVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTG
350 360 370 380 390 400
580 590 600 610 620 630
pF1KE3 NDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 NDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLP
410 420 430 440 450 460
640 650 660 670 680 690
pF1KE3 LDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKH
470 480 490 500 510 520
700 710 720 730 740 750
pF1KE3 IRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 IRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIG
530 540 550 560 570 580
760 770 780 790 800 810
pF1KE3 FTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 FTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQ
590 600 610 620 630 640
820 830 840 850 860 870
pF1KE3 KAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 KAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSD
650 660 670 680 690 700
880 890 900 910 920 930
pF1KE3 LELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 LELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIA
710 720 730 740 750 760
940 950 960 970 980 990
pF1KE3 QDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDF
770 780 790 800 810 820
1000 1010 1020 1030 1040 1050
pF1KE3 CKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 CKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLH
830 840 850 860 870 880
1060 1070 1080 1090 1100 1110
pF1KE3 QAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 QAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQRED
890 900 910 920 930 940
pF1KE3 QETAV
:::::
NP_963 QETAV
>>NP_001186196 (OMIM: 601441) diacylglycerol kinase zeta (928 aa)
initn: 6041 init1: 6041 opt: 6047 Z-score: 3559.7 bits: 670.2 E(92320): 1.7e-191
Smith-Waterman score: 6047; 94.8% identity (97.0% similar) in 931 aa overlap (187-1117:1-928)
160 170 180 190 200 210
pF1KE3 RYLRRASSHLLPADAVYDHALWGLHGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTR
. : : . . .. ::....:. .
NP_001 MEPRDGSPEARSSDSESASASSSGSERDAG
10 20 30
220 230 240 250 260 270
pF1KE3 VRPLSRRRQVALRRKAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTV
.: . :.. .:. : . .. :::::::::::::::::::::::::::::::::
NP_001 PEPDKAPRRLN-KRRFPGLRLFGH--RKAITKSGLQHLAPPPPTPGAPCSESERQIRSTV
40 50 60 70 80
280 290 300 310 320 330
pF1KE3 DWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLKSVSRRKCAACKIVVHTPCIEQLEK
90 100 110 120 130 140
340 350 360 370 380 390
pF1KE3 INFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISC
150 160 170 180 190 200
400 410 420 430 440 450
pF1KE3 SWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFK
210 220 230 240 250 260
460 470 480 490 500 510
pF1KE3 RKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFD
270 280 290 300 310 320
520 530 540 550 560 570
pF1KE3 LSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLA
330 340 350 360 370 380
580 590 600 610 620 630
pF1KE3 RTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVF
390 400 410 420 430 440
640 650 660 670 680 690
pF1KE3 NNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVV
450 460 470 480 490 500
700 710 720 730 740 750
pF1KE3 CDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMT
510 520 530 540 550 560
760 770 780 790 800 810
pF1KE3 SLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKR
570 580 590 600 610 620
820 830 840 850 860 870
pF1KE3 RSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELC
630 640 650 660 670 680
880 890 900 910 920 930
pF1KE3 RAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEI
690 700 710 720 730 740
940 950 960 970 980 990
pF1KE3 YILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQ
750 760 770 780 790 800
1000 1010 1020 1030 1040 1050
pF1KE3 ELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAA
810 820 830 840 850 860
1060 1070 1080 1090 1100 1110
pF1KE3 LGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETA
870 880 890 900 910 920
pF1KE3 V
:
NP_001 V
>>XP_005253239 (OMIM: 601441) diacylglycerol kinase zeta (934 aa)
initn: 5558 init1: 5558 opt: 6041 Z-score: 3556.2 bits: 669.6 E(92320): 2.6e-191
Smith-Waterman score: 6041; 96.2% identity (97.2% similar) in 920 aa overlap (200-1117:21-934)
170 180 190 200 210 220
pF1KE3 DAVYDHALWGLHGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTRVRPLSRRRQVALR
: .: :: : : .: . : :. .
XP_005 MSAPGAGHSAGGSCNESSALGPVEALGTEEGER-PGSLRQMWRYRSWDVP
10 20 30 40
230 240 250 260 270 280
pF1KE3 R-KAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHI
. . .::. :::::::::::::::::::::::::::::::::::::::::::::
XP_005 QIPSEAPQTQ-----KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHI
50 60 70 80 90 100
290 300 310 320 330 340
pF1KE3 WFETNVSGDFCYVGEQYCVARML-KSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRE
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_005 WFETNVSGDFCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRE
110 120 130 140 150 160
350 360 370 380 390 400
pF1KE3 SGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKV
170 180 190 200 210 220
410 420 430 440 450 460
pF1KE3 SCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEG
230 240 250 260 270 280
470 480 490 500 510 520
pF1KE3 RWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALE
290 300 310 320 330 340
530 540 550 560 570 580
pF1KE3 MYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTD
350 360 370 380 390 400
590 600 610 620 630 640
pF1KE3 EPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAH
410 420 430 440 450 460
650 660 670 680 690 700
pF1KE3 VTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQ
470 480 490 500 510 520
710 720 730 740 750 760
pF1KE3 DLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHG
530 540 550 560 570 580
770 780 790 800 810 820
pF1KE3 ERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQ
590 600 610 620 630 640
830 840 850 860 870 880
pF1KE3 PVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEP
650 660 670 680 690 700
890 900 910 920 930 940
pF1KE3 DGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGAS
710 720 730 740 750 760
950 960 970 980 990 1000
pF1KE3 ARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMH
770 780 790 800 810 820
1010 1020 1030 1040 1050 1060
pF1KE3 RDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIV
830 840 850 860 870 880
1070 1080 1090 1100 1110
pF1KE3 EAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
890 900 910 920 930
>>NP_003637 (OMIM: 601441) diacylglycerol kinase zeta is (929 aa)
initn: 5558 init1: 5558 opt: 6035 Z-score: 3552.7 bits: 668.9 E(92320): 4.1e-191
Smith-Waterman score: 6035; 94.7% identity (96.9% similar) in 932 aa overlap (187-1117:1-929)
160 170 180 190 200 210
pF1KE3 RYLRRASSHLLPADAVYDHALWGLHGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTR
. : : . . .. ::....:. .
NP_003 MEPRDGSPEARSSDSESASASSSGSERDAG
10 20 30
220 230 240 250 260 270
pF1KE3 VRPLSRRRQVALRRKAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTV
.: . :.. .:. : . .. :::::::::::::::::::::::::::::::::
NP_003 PEPDKAPRRLN-KRRFPGLRLFGH--RKAITKSGLQHLAPPPPTPGAPCSESERQIRSTV
40 50 60 70 80
280 290 300 310 320 330
pF1KE3 DWSESATYGEHIWFETNVSGDFCYVGEQYCVARML-KSVSRRKCAACKIVVHTPCIEQLE
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_003 DWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLE
90 100 110 120 130 140
340 350 360 370 380 390
pF1KE3 KINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAIS
150 160 170 180 190 200
400 410 420 430 440 450
pF1KE3 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF
210 220 230 240 250 260
460 470 480 490 500 510
pF1KE3 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF
270 280 290 300 310 320
520 530 540 550 560 570
pF1KE3 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL
330 340 350 360 370 380
580 590 600 610 620 630
pF1KE3 ARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDV
390 400 410 420 430 440
640 650 660 670 680 690
pF1KE3 FNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRV
450 460 470 480 490 500
700 710 720 730 740 750
pF1KE3 VCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTM
510 520 530 540 550 560
760 770 780 790 800 810
pF1KE3 TSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAK
570 580 590 600 610 620
820 830 840 850 860 870
pF1KE3 RRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLEL
630 640 650 660 670 680
880 890 900 910 920 930
pF1KE3 CRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDE
690 700 710 720 730 740
940 950 960 970 980 990
pF1KE3 IYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKL
750 760 770 780 790 800
1000 1010 1020 1030 1040 1050
pF1KE3 QELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAA
810 820 830 840 850 860
1060 1070 1080 1090 1100 1110
pF1KE3 ALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQET
870 880 890 900 910 920
pF1KE3 AV
::
NP_003 AV
>>NP_963291 (OMIM: 601441) diacylglycerol kinase zeta is (933 aa)
initn: 5763 init1: 5763 opt: 6023 Z-score: 3545.6 bits: 667.6 E(92320): 1e-190
Smith-Waterman score: 6023; 96.1% identity (97.1% similar) in 920 aa overlap (200-1117:21-933)
170 180 190 200 210 220
pF1KE3 DAVYDHALWGLHGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTRVRPLSRRRQVALR
: .: :: : : .: . : :. .
NP_963 MSAPGAGHSAGGSCNESSALGPVEALGTEEGER-PGSLRQMWRYRSWDVP
10 20 30 40
230 240 250 260 270 280
pF1KE3 R-KAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHI
. . .::. :::::::::::::::::::::::::::::::::::: ::::::::
NP_963 QIPSEAPQTQ-----KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWS-SATYGEHI
50 60 70 80 90 100
290 300 310 320 330 340
pF1KE3 WFETNVSGDFCYVGEQYCVARML-KSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRE
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_963 WFETNVSGDFCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRE
110 120 130 140 150 160
350 360 370 380 390 400
pF1KE3 SGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKV
170 180 190 200 210 220
410 420 430 440 450 460
pF1KE3 SCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 SCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEG
230 240 250 260 270 280
470 480 490 500 510 520
pF1KE3 RWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 RWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALE
290 300 310 320 330 340
530 540 550 560 570 580
pF1KE3 MYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 MYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTD
350 360 370 380 390 400
590 600 610 620 630 640
pF1KE3 EPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAH
410 420 430 440 450 460
650 660 670 680 690 700
pF1KE3 VTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 VTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQ
470 480 490 500 510 520
710 720 730 740 750 760
pF1KE3 DLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 DLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHG
530 540 550 560 570 580
770 780 790 800 810 820
pF1KE3 ERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 ERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQ
590 600 610 620 630 640
830 840 850 860 870 880
pF1KE3 PVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 PVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEP
650 660 670 680 690 700
890 900 910 920 930 940
pF1KE3 DGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 DGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGAS
710 720 730 740 750 760
950 960 970 980 990 1000
pF1KE3 ARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 ARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMH
770 780 790 800 810 820
1010 1020 1030 1040 1050 1060
pF1KE3 RDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 RDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIV
830 840 850 860 870 880
1070 1080 1090 1100 1110
pF1KE3 EAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_963 EAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
890 900 910 920 930
>>NP_001186195 (OMIM: 601441) diacylglycerol kinase zeta (934 aa)
initn: 5089 init1: 5089 opt: 6015 Z-score: 3540.9 bits: 666.8 E(92320): 1.9e-190
Smith-Waterman score: 6015; 94.2% identity (96.4% similar) in 937 aa overlap (187-1117:1-934)
160 170 180 190 200 210
pF1KE3 RYLRRASSHLLPADAVYDHALWGLHGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTR
. : : . . .. ::....:. .
NP_001 MEPRDGSPEARSSDSESASASSSGSERDAG
10 20 30
220 230 240 250 260 270
pF1KE3 VRPLSRRRQVALRRKAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTV
.: . :.. .:. : . .. :::::::::::::::::::::::::::::::::
NP_001 PEPDKAPRRLN-KRRFPGLRLFGH--RKAITKSGLQHLAPPPPTPGAPCSESERQIRSTV
40 50 60 70 80
280 290 300 310 320 330
pF1KE3 DWSESATYGEHIWFETNVSGDFCYVGEQYCVARML-KSVSRRKCAACKIVVHTPCIEQLE
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 DWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLE
90 100 110 120 130 140
340 350 360 370 380 390
pF1KE3 KINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAIS
150 160 170 180 190 200
400 410 420 430 440 450
pF1KE3 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF
210 220 230 240 250 260
460 470 480 490 500 510
pF1KE3 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF
270 280 290 300 310 320
520 530 540 550 560 570
pF1KE3 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL
330 340 350 360 370 380
580 590 600 610 620 630
pF1KE3 ARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDV
390 400 410 420 430 440
640 650 660 670 680 690
pF1KE3 FNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRV
450 460 470 480 490 500
700 710 720 730 740 750
pF1KE3 VCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTM
510 520 530 540 550 560
760 770 780 790 800 810
pF1KE3 TSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAK
570 580 590 600 610 620
820 830 840 850 860 870
pF1KE3 RRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLEL
630 640 650 660 670 680
880 890 900 910 920 930
pF1KE3 CRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDE
690 700 710 720 730 740
940 950 960 970 980 990
pF1KE3 IYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKL
750 760 770 780 790 800
1000 1010 1020 1030 1040 1050
pF1KE3 QELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEEN-----GETC
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 QELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENPCSPSGETC
810 820 830 840 850 860
1060 1070 1080 1090 1100 1110
pF1KE3 LHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQR
870 880 890 900 910 920
pF1KE3 EDQETAV
:::::::
NP_001 EDQETAV
930
>>NP_001186197 (OMIM: 601441) diacylglycerol kinase zeta (906 aa)
initn: 5547 init1: 5067 opt: 5072 Z-score: 2988.4 bits: 564.5 E(92320): 1.1e-159
Smith-Waterman score: 5787; 92.3% identity (94.4% similar) in 932 aa overlap (187-1117:1-906)
160 170 180 190 200 210
pF1KE3 RYLRRASSHLLPADAVYDHALWGLHGYYRRLSQRRPSGQHPGPGGRRASGTTAGTMLPTR
. : : . . .. ::....:. .
NP_001 MEPRDGSPEARSSDSESASASSSGSERDAG
10 20 30
220 230 240 250 260 270
pF1KE3 VRPLSRRRQVALRRKAAGPQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTV
.: . :.. .:. : . .. :::::::::::::::::::::::::::::::::
NP_001 PEPDKAPRRLN-KRRFPGLRLFGH--RKAITKSGLQHLAPPPPTPGAPCSESERQIRSTV
40 50 60 70 80
280 290 300 310 320 330
pF1KE3 DWSESATYGEHIWFETNVSGDFCYVGEQYCVARML-KSVSRRKCAACKIVVHTPCIEQLE
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_001 DWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLE
90 100 110 120 130 140
340 350 360 370 380 390
pF1KE3 KINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAIS
:::::::::::::::::::: :::::::::::::::::
NP_001 KINFRCKPSFRESGSRNVRE-----------------------GFQQKFTFHSKEIVAIS
150 160 170 180
400 410 420 430 440 450
pF1KE3 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF
190 200 210 220 230 240
460 470 480 490 500 510
pF1KE3 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF
250 260 270 280 290 300
520 530 540 550 560 570
pF1KE3 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL
310 320 330 340 350 360
580 590 600 610 620 630
pF1KE3 ARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDV
370 380 390 400 410 420
640 650 660 670 680 690
pF1KE3 FNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRV
430 440 450 460 470 480
700 710 720 730 740 750
pF1KE3 VCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTM
490 500 510 520 530 540
760 770 780 790 800 810
pF1KE3 TSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAK
550 560 570 580 590 600
820 830 840 850 860 870
pF1KE3 RRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLEL
610 620 630 640 650 660
880 890 900 910 920 930
pF1KE3 CRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDE
670 680 690 700 710 720
940 950 960 970 980 990
pF1KE3 IYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKL
730 740 750 760 770 780
1000 1010 1020 1030 1040 1050
pF1KE3 QELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAA
790 800 810 820 830 840
1060 1070 1080 1090 1100 1110
pF1KE3 ALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQET
850 860 870 880 890 900
pF1KE3 AV
::
NP_001 AV
1117 residues in 1 query sequences
64369986 residues in 92320 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:25:53 2019 done: Thu Oct 24 21:25:55 2019
Total Scan time: 8.870 Total Display time: 0.270
Function used was FASTA [36.3.4 Apr, 2011]