Result of FASTA (omim) for
pF1KE3182
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3182, 419 aa
1>>>pF1KE3182 419 - 419 aa - 419 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7457+/-0.000308; mu= 12.5337+/- 0.019
mean_var=144.5966+/-29.532, 0's: 0 Z-trim(120.8): 114 B-trim: 983 in 2/56
Lambda= 0.106658
statistics sampled from 37720 (37856) to 37720 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.412), width: 16
Scan time: 5.140
The best scores are: opt bits E(91774)
NP_001938 (OMIM: 602749) dual specificity protein ( 419) 2806 443.1 6.6e-124
NP_001937 (OMIM: 146110,602748,615269) dual specif ( 381) 1787 286.3 9.8e-77
NP_001386 (OMIM: 300134) dual specificity protein ( 384) 1069 175.8 1.8e-43
XP_011529426 (OMIM: 300134) dual specificity prote ( 384) 1069 175.8 1.8e-43
NP_001305432 (OMIM: 300134) dual specificity prote ( 384) 1069 175.8 1.8e-43
XP_011529425 (OMIM: 300134) dual specificity prote ( 415) 1069 175.8 1.9e-43
XP_016859035 (OMIM: 603068) dual specificity prote ( 342) 588 101.7 3.1e-21
NP_073143 (OMIM: 146110,602748,615269) dual specif ( 235) 558 97.0 5.8e-20
NP_009138 (OMIM: 608867) dual specificity protein ( 482) 484 85.9 2.6e-16
XP_011518235 (OMIM: 602038) dual specificity prote ( 625) 484 86.0 3.2e-16
XP_011518234 (OMIM: 602038) dual specificity prote ( 625) 484 86.0 3.2e-16
NP_004411 (OMIM: 602038) dual specificity protein ( 625) 484 86.0 3.2e-16
NP_004409 (OMIM: 603068) dual specificity protein ( 314) 479 84.9 3.3e-16
NP_476499 (OMIM: 602747) dual specificity protein ( 303) 477 84.6 4e-16
XP_011542730 (OMIM: 602747) dual specificity prote ( 303) 477 84.6 4e-16
NP_004408 (OMIM: 600714) dual specificity protein ( 367) 478 84.8 4.1e-16
NP_001385 (OMIM: 602747) dual specificity protein ( 394) 477 84.7 4.8e-16
NP_085143 (OMIM: 607175) dual specificity protein ( 665) 462 82.6 3.5e-15
XP_011519158 (OMIM: 607175) dual specificity prote ( 665) 462 82.6 3.5e-15
XP_006719218 (OMIM: 607175) dual specificity prote ( 665) 462 82.6 3.5e-15
NP_004410 (OMIM: 603069) dual specificity protein ( 384) 425 76.7 1.2e-13
XP_005253545 (OMIM: 607175) dual specificity prote ( 517) 369 68.2 5.9e-11
XP_016875477 (OMIM: 607175) dual specificity prote ( 517) 369 68.2 5.9e-11
NP_543152 (OMIM: 611437) dual specificity protein ( 217) 328 61.5 2.5e-09
NP_001154802 (OMIM: 606778) protein phosphatase Sl ( 692) 329 62.2 5.1e-09
NP_001154803 (OMIM: 606778) protein phosphatase Sl ( 703) 329 62.2 5.2e-09
XP_016874981 (OMIM: 606778) protein phosphatase Sl ( 923) 329 62.3 6.3e-09
XP_005269042 (OMIM: 606778) protein phosphatase Sl ( 969) 329 62.3 6.6e-09
XP_011536803 (OMIM: 606778) protein phosphatase Sl ( 969) 329 62.3 6.6e-09
XP_011536802 (OMIM: 606778) protein phosphatase Sl ( 969) 329 62.3 6.6e-09
XP_016880743 (OMIM: 606779) protein phosphatase Sl ( 480) 324 61.2 6.7e-09
XP_016874980 (OMIM: 606778) protein phosphatase Sl (1033) 329 62.3 6.9e-09
XP_005269041 (OMIM: 606778) protein phosphatase Sl (1049) 329 62.3 6.9e-09
NP_061857 (OMIM: 606778) protein phosphatase Sling (1049) 329 62.3 6.9e-09
XP_011536799 (OMIM: 606778) protein phosphatase Sl (1060) 329 62.3 7e-09
XP_016880742 (OMIM: 606779) protein phosphatase Sl ( 529) 324 61.3 7.2e-09
NP_064570 (OMIM: 616778) dual specificity protein ( 184) 312 59.0 1.2e-08
NP_001273484 (OMIM: 616778) dual specificity prote ( 205) 312 59.1 1.3e-08
XP_016880741 (OMIM: 606779) protein phosphatase Sl (1328) 324 61.7 1.4e-08
XP_011523709 (OMIM: 606779) protein phosphatase Sl (1347) 324 61.7 1.4e-08
XP_011523708 (OMIM: 606779) protein phosphatase Sl (1347) 324 61.7 1.4e-08
XP_011523707 (OMIM: 606779) protein phosphatase Sl (1394) 324 61.7 1.5e-08
XP_006722212 (OMIM: 606779) protein phosphatase Sl (1401) 324 61.7 1.5e-08
XP_011523706 (OMIM: 606779) protein phosphatase Sl (1405) 324 61.7 1.5e-08
NP_203747 (OMIM: 606779) protein phosphatase Sling (1423) 324 61.7 1.5e-08
XP_011523704 (OMIM: 606779) protein phosphatase Sl (1430) 324 61.7 1.5e-08
XP_005258116 (OMIM: 606779) protein phosphatase Sl (1430) 324 61.7 1.5e-08
XP_016880740 (OMIM: 606779) protein phosphatase Sl (1449) 324 61.7 1.5e-08
XP_005258115 (OMIM: 606779) protein phosphatase Sl (1450) 324 61.7 1.5e-08
NP_001269058 (OMIM: 606779) protein phosphatase Sl (1450) 324 61.7 1.5e-08
>>NP_001938 (OMIM: 602749) dual specificity protein phos (419 aa)
initn: 2806 init1: 2806 opt: 2806 Z-score: 2346.1 bits: 443.1 E(91774): 6.6e-124
Smith-Waterman score: 2806; 100.0% identity (100.0% similar) in 419 aa overlap (1-419:1-419)
10 20 30 40 50 60
pF1KE3 MKNQLRGPPARAHMSTSGAAAAGGTRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKNQLRGPPARAHMSTSGAAAAGGTRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHAD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 HWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDF
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 VKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
370 380 390 400 410
>>NP_001937 (OMIM: 146110,602748,615269) dual specificit (381 aa)
initn: 1431 init1: 1399 opt: 1787 Z-score: 1499.2 bits: 286.3 E(91774): 9.8e-77
Smith-Waterman score: 1787; 71.9% identity (90.7% similar) in 367 aa overlap (55-419:18-381)
30 40 50 60 70 80
pF1KE3 TRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWLQEELEARGGASLLLLDCRPHELFE
:.. ::.:.:: :. :::.::::.::.:
NP_001 MIDTLRPVPFASEMAISKTVAWLNEQLEL-GNERLLLMDCRPQELYE
10 20 30 40
90 100 110 120 130 140
pF1KE3 SSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAATVLLYDEATAEWQ
:::::.:::.::::.:::::.:::::.:... :..::. :: . ::.::::....:.
NP_001 SSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWN
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE3 PEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVDSSSSPSSSPPTSV
. :. :::::::.::.:.::.:.::.:::.:::.:.: :::::.:.: : ::::: :
NP_001 ENTGGE-SVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCS-SSSPPLPV
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE3 LGLGGLRISSDCS-DGESDREL-PSSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTN
::::::::::: : : ::: . :.:::.:::::. .:::.:::.:::.:::::::::::
NP_001 LGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTN
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE3 LDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARS
:::: ..:::::::::::::: ::..::: :::::::::::::::::::::::::::::.
NP_001 LDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARG
230 240 250 260 270 280
330 340 350 360 370 380
pF1KE3 KKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFE
:.:::::::::::::::::::::::::.:::.:::::.:: :::::::::::::::::::
NP_001 KNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFE
290 300 310 320 330 340
390 400 410
pF1KE3 RTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
:::::::::::.. ..::::.::.:.:.. ...:.::
NP_001 RTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
350 360 370 380
>>NP_001386 (OMIM: 300134) dual specificity protein phos (384 aa)
initn: 1159 init1: 798 opt: 1069 Z-score: 902.1 bits: 175.8 E(91774): 1.8e-43
Smith-Waterman score: 1262; 56.0% identity (75.4% similar) in 382 aa overlap (55-413:6-381)
30 40 50 60 70 80
pF1KE3 TRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWLQEELEARGGASLLLLDCRPHELFE
.: ::..:: . ::::::: .::.:
NP_001 MEGLGRSCLWLRREL-SPPRPRLLLLDCRSRELYE
10 20 30
90 100 110 120 130
pF1KE3 SSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAATVLLYDEA-----
:..: :...:.:.:.:::::.:.: .:...:. . : :::::..
NP_001 SARIGGALSVALPALLLRRLRRGSLSVRALLPGPPLQPP-----PPAPVLLYDQGGGRRR
40 50 60 70 80
140 150 160 170 180 190
pF1KE3 --TAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVDSSSSPS
:: . : :::: ::::::..: ::::::::..::.: . :::.. . .. :
NP_001 RGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGSS
90 100 110 120 130 140
200 210 220 230 240 250
pF1KE3 SSP---PTSVLGLGGLRISSDCSDGES--DRELPSSATESDG-SPVPSS-QPAFPVQILP
.: :. :.:::.: ..:::::.:: ::. : . .:.: .: : . . .:::::::
NP_001 MAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILP
150 160 170 180 190 200
260 270 280 290 300 310
pF1KE3 YLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFF
:::: :.::.::. :.: ::.::::::::::: ::..:.: :::::::::::::::.::
NP_001 NLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFF
210 220 230 240 250 260
320 330 340 350 360 370
pF1KE3 PEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISP
:::: ::::: :..::::::::::.::::::::::::::..::::::::.::::::::::
NP_001 PEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISP
270 280 290 300 310 320
380 390 400 410
pF1KE3 NFNFMGQLLDFERTLGL---------SSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
:::::::::::::.: : :. . ::. .:.:::. . : :
NP_001 NFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT
330 340 350 360 370 380
>>XP_011529426 (OMIM: 300134) dual specificity protein p (384 aa)
initn: 1159 init1: 798 opt: 1069 Z-score: 902.1 bits: 175.8 E(91774): 1.8e-43
Smith-Waterman score: 1262; 56.0% identity (75.4% similar) in 382 aa overlap (55-413:6-381)
30 40 50 60 70 80
pF1KE3 TRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWLQEELEARGGASLLLLDCRPHELFE
.: ::..:: . ::::::: .::.:
XP_011 MEGLGRSCLWLRREL-SPPRPRLLLLDCRSRELYE
10 20 30
90 100 110 120 130
pF1KE3 SSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAATVLLYDEA-----
:..: :...:.:.:.:::::.:.: .:...:. . : :::::..
XP_011 SARIGGALSVALPALLLRRLRRGSLSVRALLPGPPLQPP-----PPAPVLLYDQGGGRRR
40 50 60 70 80
140 150 160 170 180 190
pF1KE3 --TAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVDSSSSPS
:: . : :::: ::::::..: ::::::::..::.: . :::.. . .. :
XP_011 RGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGSS
90 100 110 120 130 140
200 210 220 230 240 250
pF1KE3 SSP---PTSVLGLGGLRISSDCSDGES--DRELPSSATESDG-SPVPSS-QPAFPVQILP
.: :. :.:::.: ..:::::.:: ::. : . .:.: .: : . . .:::::::
XP_011 MAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILP
150 160 170 180 190 200
260 270 280 290 300 310
pF1KE3 YLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFF
:::: :.::.::. :.: ::.::::::::::: ::..:.: :::::::::::::::.::
XP_011 NLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFF
210 220 230 240 250 260
320 330 340 350 360 370
pF1KE3 PEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISP
:::: ::::: :..::::::::::.::::::::::::::..::::::::.::::::::::
XP_011 PEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISP
270 280 290 300 310 320
380 390 400 410
pF1KE3 NFNFMGQLLDFERTLGL---------SSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
:::::::::::::.: : :. . ::. .:.:::. . : :
XP_011 NFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT
330 340 350 360 370 380
>>NP_001305432 (OMIM: 300134) dual specificity protein p (384 aa)
initn: 1159 init1: 798 opt: 1069 Z-score: 902.1 bits: 175.8 E(91774): 1.8e-43
Smith-Waterman score: 1262; 56.0% identity (75.4% similar) in 382 aa overlap (55-413:6-381)
30 40 50 60 70 80
pF1KE3 TRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWLQEELEARGGASLLLLDCRPHELFE
.: ::..:: . ::::::: .::.:
NP_001 MEGLGRSCLWLRREL-SPPRPRLLLLDCRSRELYE
10 20 30
90 100 110 120 130
pF1KE3 SSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAATVLLYDEA-----
:..: :...:.:.:.:::::.:.: .:...:. . : :::::..
NP_001 SARIGGALSVALPALLLRRLRRGSLSVRALLPGPPLQPP-----PPAPVLLYDQGGGRRR
40 50 60 70 80
140 150 160 170 180 190
pF1KE3 --TAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVDSSSSPS
:: . : :::: ::::::..: ::::::::..::.: . :::.. . .. :
NP_001 RGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGSS
90 100 110 120 130 140
200 210 220 230 240 250
pF1KE3 SSP---PTSVLGLGGLRISSDCSDGES--DRELPSSATESDG-SPVPSS-QPAFPVQILP
.: :. :.:::.: ..:::::.:: ::. : . .:.: .: : . . .:::::::
NP_001 MAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILP
150 160 170 180 190 200
260 270 280 290 300 310
pF1KE3 YLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFF
:::: :.::.::. :.: ::.::::::::::: ::..:.: :::::::::::::::.::
NP_001 NLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFF
210 220 230 240 250 260
320 330 340 350 360 370
pF1KE3 PEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISP
:::: ::::: :..::::::::::.::::::::::::::..::::::::.::::::::::
NP_001 PEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISP
270 280 290 300 310 320
380 390 400 410
pF1KE3 NFNFMGQLLDFERTLGL---------SSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
:::::::::::::.: : :. . ::. .:.:::. . : :
NP_001 NFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT
330 340 350 360 370 380
>>XP_011529425 (OMIM: 300134) dual specificity protein p (415 aa)
initn: 1159 init1: 798 opt: 1069 Z-score: 901.7 bits: 175.8 E(91774): 1.9e-43
Smith-Waterman score: 1263; 52.8% identity (72.7% similar) in 417 aa overlap (20-413:3-412)
10 20 30 40 50 60
pF1KE3 MKNQLRGPPARAHMSTSGAAAAGGTRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWL
:: : .. . :: . . .:. . .. .: ::
XP_011 MEAAQVGPKGRQLPGKHVVAPVVQRVGSRSPMEGLG-RSCLWL
10 20 30 40
70 80 90 100 110 120
pF1KE3 QEELEARGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHAD
..:: ::::::: .::.::..: :...:.:.:.:::::.:.: .:...:.
XP_011 RRELSP-PRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPPL
50 60 70 80 90 100
130 140 150 160 170
pF1KE3 KERFATRCKAATVLLYDEA-------TAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQG
. : :::::.. :: . : :::: ::::::..: ::::::
XP_011 QPP-----PPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQG
110 120 130 140 150
180 190 200 210 220
pF1KE3 GFNKFQTEYSEHCETNVDSSSSPSSSP---PTSVLGLGGLRISSDCSDGES--DRELPSS
::..::.: . :::.. . .. : .: :. :.:::.: ..:::::.:: ::. :
XP_011 GFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSC
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE3 ATESDG-SPVPSS-QPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFE
. .:.: .: : . . .::::::: :::: :.::.::. :.: ::.::::::::::: ::
XP_011 GLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFE
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE3 HGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYL
..:.: :::::::::::::::.:::::: ::::: :..::::::::::.:::::::::::
XP_011 KNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYL
280 290 300 310 320 330
350 360 370 380 390
pF1KE3 MQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGL---------SSPCDNHASS
:::..::::::::.:::::::::::::::::::::::.: : :. . ::.
XP_011 MQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASN
340 350 360 370 380 390
400 410
pF1KE3 EQLYFSTPTNHNLFPLNTLEST
.:.:::. . : :
XP_011 PPSFFTTPTSDGAFELAPT
400 410
>>XP_016859035 (OMIM: 603068) dual specificity protein p (342 aa)
initn: 557 init1: 339 opt: 588 Z-score: 502.7 bits: 101.7 E(91774): 3.1e-21
Smith-Waterman score: 588; 36.6% identity (62.5% similar) in 328 aa overlap (65-382:20-336)
40 50 60 70 80 90
pF1KE3 SGSGAGTGAGAATGAGAMPCKSAEWLQEELEARGGASLLLLDCRPHELFESSHIETAINL
. : . ::::::: : :...: .
XP_016 MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAARPV
10 20 30 40
100 110 120 130 140 150
pF1KE3 AIPGLMLRRLRKGNLPIRS-IIPNHADKERFATRCKAATVLLYDEATAEWQP-EPGAPAS
.:. :: : . . ..:..: . :.. : . : ... ::..: .: .::
XP_016 PWNALLRRRARGPPAAVLACLLPDRALRTRLV-RGELARAVVLDEGSASVAELRPDSPAH
50 60 70 80 90 100
160 170 180 190 200
pF1KE3 VL-GLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVDSSSS-PSSSP-PTSVLGLGG
:: . ::.. : .:.:.: . .. . ::: . :.. : . :. :
XP_016 VLLAALLHETRAGPTAVYFLRG------EQAGRPWPAPPDSSPAFPADRALPLLAGGFDG
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE3 LRISSDCSDGESDRELPSSATESDGSPVPSSQ-PAF----PVQILPYLYLGCAKDSTNLD
.. . : : :. :. .: . .:. :.. ::.:::::.:: . :..:.
XP_016 FQ--GCCPDLCSEAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQ
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE3 VLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKK
: :: .:::. . :: :: : : ::.::. :. ..: .: :::.::: ....
XP_016 GLQACGITAVLNVSASCPNHFE--GLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSG
230 240 250 260 270
330 340 350 360 370 380
pF1KE3 CGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERT
::::: ::::::.:. .:::::. . :..:.::::.... :::::.::::::.::
XP_016 GRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQ
280 290 300 310 320 330
390 400 410
pF1KE3 LGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
XP_016 VLCH
340
>>NP_073143 (OMIM: 146110,602748,615269) dual specificit (235 aa)
initn: 927 init1: 558 opt: 558 Z-score: 479.9 bits: 97.0 E(91774): 5.8e-20
Smith-Waterman score: 737; 40.8% identity (55.1% similar) in 365 aa overlap (55-419:18-235)
30 40 50 60 70 80
pF1KE3 TRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWLQEELEARGGASLLLLDCRPHELFE
:.. ::.:.:: :. :::.::::.::.:
NP_073 MIDTLRPVPFASEMAISKTVAWLNEQLEL-GNERLLLMDCRPQELYE
10 20 30 40
90 100 110 120 130 140
pF1KE3 SSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAATVLLYDEATAEWQ
:::::.:::.::::.:::::.:::::.:... :..::. :: . ::.::::....:.
NP_073 SSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWN
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE3 PEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVDSSSSPSSSPPTSV
. :. :::::::.::.:.::.:.::.
NP_073 ENTGGE-SVLGLLLKKLKDEGCRAFYLE--------------------------------
110 120 130
210 220 230 240 250 260
pF1KE3 LGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTNLD
NP_073 ------------------------------------------------------------
270 280 290 300 310 320
pF1KE3 VLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKK
::::.:.
NP_073 -----------------------------------------------------DEARGKN
140
330 340 350 360 370 380
pF1KE3 CGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERT
:::::::::::::::::::::::::.:::.:::::.:: :::::::::::::::::::::
NP_073 CGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERT
150 160 170 180 190 200
390 400 410
pF1KE3 LGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
:::::::::.. ..::::.::.:.:.. ...:.::
NP_073 LGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
210 220 230
>>NP_009138 (OMIM: 608867) dual specificity protein phos (482 aa)
initn: 540 init1: 476 opt: 484 Z-score: 414.3 bits: 85.9 E(91774): 2.6e-16
Smith-Waterman score: 629; 33.0% identity (62.4% similar) in 364 aa overlap (31-385:129-462)
10 20 30 40 50
pF1KE3 MKNQLRGPPARAHMSTSGAAAAGGTRAGSEPGAGSGSG-AGTGAGAATGAGAMPCKSAEW
:..: :: .:: :. .: :.
NP_009 AGTTTTAIGTSTTCPANQMVNNNENTGSLSPSSGVGSPVSGTPKQLASIKIIYPNDLAKK
100 110 120 130 140 150
60 70 80 90 100 110
pF1KE3 L----QEELEARGGASLLLLDCRPHELFESSHIETAINLAIPG-LMLRRLRKGNLPIRSI
. . .: ..: ...:::: ...:::. :... . :::..:.. . ..
NP_009 MTKCSKSHLPSQGP---VIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDL
160 170 180 190 200 210
120 130 140 150 160 170
pF1KE3 IPNHADKERFATRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYYLQGG
: . :. : : . ...::: : : : :.. : ..:..:. .: . :.::
NP_009 ISCREGKDSFK-RIFSKEIIVYDENTNE--PSRVMPSQPLHIVLESLKREGKEPLVLKGG
220 230 240 250 260 270
180 190 200 210 220 230
pF1KE3 FNKFQTEYSEHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDG
...:. .. . :..... . .: :: .:. ::.
NP_009 LSSFKQNHENLCDNSLQLQECRE-------VG-GGASAASSL--------LPQ-------
280 290 300
240 250 260 270 280 290
pF1KE3 SPVPSS---QPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEF
:.:.. . : . :::.:.:: .:. .::.. . .: :..::: .:: . : :
NP_009 -PIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLF
310 320 330 340 350 360
300 310 320 330 340 350
pF1KE3 TYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMN
.::..: .: .::: :.: ::. ::.::.. :.:.:: ::.:::.:...::::..
NP_009 NYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTR
370 380 390 400 410 420
360 370 380 390 400 410
pF1KE3 LSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLF
....::: ::: :. ::::.:::::::.::. :
NP_009 MTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVETVV
430 440 450 460 470 480
pF1KE3 PLNTLEST
>>XP_011518235 (OMIM: 602038) dual specificity protein p (625 aa)
initn: 526 init1: 348 opt: 484 Z-score: 412.9 bits: 86.0 E(91774): 3.2e-16
Smith-Waterman score: 569; 35.5% identity (61.7% similar) in 324 aa overlap (67-387:21-302)
40 50 60 70 80 90
pF1KE3 SGAGTGAGAATGAGAMPCKSAEWLQEELEARGG-ASLLLLDCRPHELFESSHIETAINLA
::: .. :..: : ..: :. ...:.
XP_011 MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNIC
10 20 30 40 50
100 110 120 130 140 150
pF1KE3 IPGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAATVLLYDEATAEWQPEPGAPASVLG
:. :::..:.. : .: : .. :: . :..::..: . : : :.
XP_011 CSKLVKRRLQQGKVTIAELIQPAARSQVEAT--EPQDVVVYDQSTRD--ASVLAADSFLS
60 70 80 90 100
160 170 180 190 200 210
pF1KE3 LLLQKLRDDGC--QAYYLQGGFNKFQTEYSEHCETNVDSSSSPSSSPPTSVLGLGGLRIS
.::.:: ::: .. : ::: :.. . :: ..:.. : : .:
XP_011 ILLSKL--DGCFDSVAILTGGFATFSSCFPGLCE------GKPAALLPMS--------LS
110 120 130 140 150
220 230 240 250 260 270
pF1KE3 SDCSDGESDRELPSSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTNLDVLGKYGIKY
. : :::: . .:::.:::: :: : :.. . ::.:
XP_011 QPCL------------------PVPSVGLT---RILPHLYLGSQKDVLNKDLMTQNGISY
160 170 180
280 290 300 310 320 330
pF1KE3 ILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLA
.::.. . :. . : . ..::.:.. ..: .. ..: :::.:. ..: :.:::::
XP_011 VLNASNSCPKP-DFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLA
190 200 210 220 230 240
340 350 360 370 380 390
pF1KE3 GISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLSSPCDN
:::::.:...::.:. :..: .::: ::: .. .:::::::.::::..::.: :
XP_011 GISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQG
250 260 270 280 290 300
400 410
pF1KE3 HASSEQLYFSTPTNHNLFPLNTLEST
XP_011 DPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPAPPTPPATS
310 320 330 340 350 360
419 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 16:11:55 2019 done: Tue Jul 16 16:11:56 2019
Total Scan time: 5.140 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]