Result of FASTA (omim) for
pF1KE3008
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3008, 89 aa
1>>>pF1KE3008 89 - 89 aa - 89 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4751+/-0.000304; mu= 12.9491+/- 0.019
mean_var=49.0983+/- 9.892, 0's: 0 Z-trim(116.2): 49 B-trim: 8 in 1/53
Lambda= 0.183038
statistics sampled from 27176 (27225) to 27176 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.319), width: 16
Scan time: 3.400
The best scores are: opt bits E(85289)
NP_690865 (OMIM: 615700) pyrin domain-containing p ( 89) 552 152.5 8.5e-38
NP_660183 (OMIM: 606838) apoptosis-associated spec ( 176) 344 97.7 5.1e-21
NP_037390 (OMIM: 606838) apoptosis-associated spec ( 195) 344 97.8 5.5e-21
NP_001185465 (OMIM: 134610,249100,608107) pyrin is ( 445) 164 50.4 2.2e-06
XP_016878725 (OMIM: 134610,249100,608107) PREDICTE ( 780) 164 50.6 3.5e-06
NP_000234 (OMIM: 134610,249100,608107) pyrin isofo ( 781) 164 50.6 3.5e-06
XP_011518345 (OMIM: 609662) PREDICTED: NACHT, LRR ( 655) 143 45.0 0.00014
NP_789791 (OMIM: 609662) NACHT, LRR and PYD domain ( 655) 143 45.0 0.00014
XP_011518233 (OMIM: 609650) PREDICTED: NACHT, LRR ( 703) 140 44.2 0.00026
XP_016872741 (OMIM: 609650) PREDICTED: NACHT, LRR ( 771) 140 44.2 0.00028
NP_001263629 (OMIM: 609650) NACHT, LRR and PYD dom ( 891) 140 44.3 0.00032
NP_612202 (OMIM: 609650) NACHT, LRR and PYD domain ( 892) 140 44.3 0.00032
XP_011542357 (OMIM: 120100,191900,606416,607115) P ( 865) 130 41.6 0.0019
XP_011542355 (OMIM: 120100,191900,606416,607115) P ( 922) 130 41.6 0.002
XP_016855673 (OMIM: 120100,191900,606416,607115) P ( 922) 130 41.6 0.002
NP_899632 (OMIM: 120100,191900,606416,607115) NACH ( 922) 130 41.6 0.002
XP_016855672 (OMIM: 120100,191900,606416,607115) P ( 979) 130 41.7 0.0021
NP_001120934 (OMIM: 120100,191900,606416,607115) N ( 979) 130 41.7 0.0021
NP_001120933 (OMIM: 120100,191900,606416,607115) N ( 979) 130 41.7 0.0021
NP_001230062 (OMIM: 120100,191900,606416,607115) N (1034) 130 41.7 0.0022
XP_016855670 (OMIM: 120100,191900,606416,607115) P (1036) 130 41.7 0.0022
XP_016855671 (OMIM: 120100,191900,606416,607115) P (1036) 130 41.7 0.0022
NP_004886 (OMIM: 120100,191900,606416,607115) NACH (1036) 130 41.7 0.0022
NP_001073289 (OMIM: 120100,191900,606416,607115) N (1036) 130 41.7 0.0022
XP_011542350 (OMIM: 120100,191900,606416,607115) P (1036) 130 41.7 0.0022
>>NP_690865 (OMIM: 615700) pyrin domain-containing prote (89 aa)
initn: 552 init1: 552 opt: 552 Z-score: 799.5 bits: 152.5 E(85289): 8.5e-38
Smith-Waterman score: 552; 100.0% identity (100.0% similar) in 89 aa overlap (1-89:1-89)
10 20 30 40 50 60
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASY
10 20 30 40 50 60
70 80
pF1KE3 YEDYAAELVVAVLRDMRMLEEAARLQRAA
:::::::::::::::::::::::::::::
NP_690 YEDYAAELVVAVLRDMRMLEEAARLQRAA
70 80
>>NP_660183 (OMIM: 606838) apoptosis-associated speck-li (176 aa)
initn: 344 init1: 344 opt: 344 Z-score: 498.3 bits: 97.7 E(85289): 5.1e-21
Smith-Waterman score: 344; 64.8% identity (81.8% similar) in 88 aa overlap (1-88:1-88)
10 20 30 40 50 60
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASY
:: :.::: .::::: :::::::.:: .::::::. ::::::: ..: .:::::::. :
NP_660 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
10 20 30 40 50 60
70 80
pF1KE3 YEDYAAELVVAVLRDMRMLEEAARLQRAA
: :.:::.. ::::: . : :..:: :
NP_660 LETYGAELTANVLRDMGLQEMAGQLQAATHQGLHFIDQHRAALIARVTNVEWLLDALYGK
70 80 90 100 110 120
>>NP_037390 (OMIM: 606838) apoptosis-associated speck-li (195 aa)
initn: 344 init1: 344 opt: 344 Z-score: 497.7 bits: 97.8 E(85289): 5.5e-21
Smith-Waterman score: 344; 64.8% identity (81.8% similar) in 88 aa overlap (1-88:1-88)
10 20 30 40 50 60
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASY
:: :.::: .::::: :::::::.:: .::::::. ::::::: ..: .:::::::. :
NP_037 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
10 20 30 40 50 60
70 80
pF1KE3 YEDYAAELVVAVLRDMRMLEEAARLQRAA
: :.:::.. ::::: . : :..:: :
NP_037 LETYGAELTANVLRDMGLQEMAGQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRA
70 80 90 100 110 120
>>NP_001185465 (OMIM: 134610,249100,608107) pyrin isofor (445 aa)
initn: 164 init1: 164 opt: 164 Z-score: 235.5 bits: 50.4 E(85289): 2.2e-06
Smith-Waterman score: 164; 35.6% identity (70.1% similar) in 87 aa overlap (3-89:4-90)
10 20 30 40 50
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVAS
: . .:..::.:.: ...:::.:: .. ... ::::. . . : .. ::.
NP_001 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
10 20 30 40 50 60
60 70 80
pF1KE3 YYEDYAAELVVAVLRDMRMLEEAARLQRAA
: :.::..:.. ::: . . : .:.:::
NP_001 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQGRPPDTAASPRCHAQEGDPVDGTCVRDS
70 80 90 100 110 120
>>XP_016878725 (OMIM: 134610,249100,608107) PREDICTED: p (780 aa)
initn: 164 init1: 164 opt: 164 Z-score: 231.9 bits: 50.6 E(85289): 3.5e-06
Smith-Waterman score: 164; 35.6% identity (70.1% similar) in 87 aa overlap (3-89:4-90)
10 20 30 40 50
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVAS
: . .:..::.:.: ...:::.:: .. ... ::::. . . : .. ::.
XP_016 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
10 20 30 40 50 60
60 70 80
pF1KE3 YYEDYAAELVVAVLRDMRMLEEAARLQRAA
: :.::..:.. ::: . . : .:.:::
XP_016 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT
70 80 90 100 110 120
>>NP_000234 (OMIM: 134610,249100,608107) pyrin isoform 1 (781 aa)
initn: 164 init1: 164 opt: 164 Z-score: 231.9 bits: 50.6 E(85289): 3.5e-06
Smith-Waterman score: 164; 35.6% identity (70.1% similar) in 87 aa overlap (3-89:4-90)
10 20 30 40 50
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVAS
: . .:..::.:.: ...:::.:: .. ... ::::. . . : .. ::.
NP_000 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
10 20 30 40 50 60
60 70 80
pF1KE3 YYEDYAAELVVAVLRDMRMLEEAARLQRAA
: :.::..:.. ::: . . : .:.:::
NP_000 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT
70 80 90 100 110 120
>>XP_011518345 (OMIM: 609662) PREDICTED: NACHT, LRR and (655 aa)
initn: 142 init1: 142 opt: 143 Z-score: 203.1 bits: 45.0 E(85289): 0.00014
Smith-Waterman score: 143; 37.0% identity (65.4% similar) in 81 aa overlap (5-85:10-90)
10 20 30 40 50
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDK
:::.: .: .: ...::.:. : . : :: . :: : : :::..
XP_011 MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAEL
10 20 30 40 50 60
60 70 80
pF1KE3 LVASYYEDYAAELVVAVLRDMRMLEEAARLQRAA
:...: : :...:. :. : .:: . .:
XP_011 LISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGR
70 80 90 100 110 120
>>NP_789791 (OMIM: 609662) NACHT, LRR and PYD domains-co (655 aa)
initn: 142 init1: 142 opt: 143 Z-score: 203.1 bits: 45.0 E(85289): 0.00014
Smith-Waterman score: 143; 37.0% identity (65.4% similar) in 81 aa overlap (5-85:10-90)
10 20 30 40 50
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDK
:::.: .: .: ...::.:. : . : :: . :: : : :::..
NP_789 MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAEL
10 20 30 40 50 60
60 70 80
pF1KE3 LVASYYEDYAAELVVAVLRDMRMLEEAARLQRAA
:...: : :...:. :. : .:: . .:
NP_789 LISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGR
70 80 90 100 110 120
>>XP_011518233 (OMIM: 609650) PREDICTED: NACHT, LRR and (703 aa)
initn: 143 init1: 79 opt: 140 Z-score: 198.4 bits: 44.2 E(85289): 0.00026
Smith-Waterman score: 140; 36.8% identity (64.4% similar) in 87 aa overlap (1-86:15-98)
10 20 30 40
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTV-PLREGFERIPRGALG
... :: .: .::.:. :.::.:. :: : : .: . :: : :
XP_011 MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGP--DG-RSIPWGRLE
10 20 30 40 50
50 60 70 80
pF1KE3 QLDIVDLTDKLVASYYEDYAAELVVAVLRDMRMLEEAARLQRAA
. : :::...:. : . : :.. .:. . ::.::
XP_011 RADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSE
60 70 80 90 100 110
XP_011 YKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRS
120 130 140 150 160 170
>>XP_016872741 (OMIM: 609650) PREDICTED: NACHT, LRR and (771 aa)
initn: 143 init1: 79 opt: 140 Z-score: 197.8 bits: 44.2 E(85289): 0.00028
Smith-Waterman score: 140; 36.8% identity (64.4% similar) in 87 aa overlap (1-86:15-98)
10 20 30 40
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTV-PLREGFERIPRGALG
... :: .: .::.:. :.::.:. :: : : .: . :: : :
XP_016 MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGP--DG-RSIPWGRLE
10 20 30 40 50
50 60 70 80
pF1KE3 QLDIVDLTDKLVASYYEDYAAELVVAVLRDMRMLEEAARLQRAA
. : :::...:. : . : :.. .:. . ::.::
XP_016 RADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSE
60 70 80 90 100 110
XP_016 YKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRS
120 130 140 150 160 170
89 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:46:38 2016 done: Mon Nov 7 20:46:39 2016
Total Scan time: 3.400 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]