Result of FASTA (ccds) for
pF1KE2751
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2751, 272 aa
1>>>pF1KE2751 272 - 272 aa - 272 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1277+/-0.000901; mu= 8.5637+/- 0.054
mean_var=173.1605+/-32.344, 0's: 0 Z-trim(113.0): 35 B-trim: 52 in 1/49
Lambda= 0.097465
statistics sampled from 13876 (13906) to 13876 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.754), E-opt: 0.2 (0.416), width: 16
Scan time: 1.150
The best scores are: opt bits E(33420)
CCDS5135.1 RSPO3 gene_id:84870|Hs109|chr6 ( 272) 1951 285.8 2.3e-77
CCDS41304.1 RSPO1 gene_id:284654|Hs109|chr1 ( 263) 885 135.9 3e-32
CCDS55591.1 RSPO1 gene_id:284654|Hs109|chr1 ( 236) 842 129.8 1.8e-30
CCDS6307.1 RSPO2 gene_id:340419|Hs109|chr8 ( 243) 825 127.4 9.8e-30
CCDS42846.1 RSPO4 gene_id:343637|Hs109|chr20 ( 234) 667 105.2 4.7e-23
CCDS83314.1 RSPO2 gene_id:340419|Hs109|chr8 ( 176) 645 102.0 3.3e-22
CCDS55590.1 RSPO1 gene_id:284654|Hs109|chr1 ( 200) 565 90.8 8.7e-19
CCDS64953.1 RSPO2 gene_id:340419|Hs109|chr8 ( 179) 494 80.7 8.1e-16
CCDS42845.1 RSPO4 gene_id:343637|Hs109|chr20 ( 172) 448 74.2 7e-14
>>CCDS5135.1 RSPO3 gene_id:84870|Hs109|chr6 (272 aa)
initn: 1951 init1: 1951 opt: 1951 Z-score: 1502.6 bits: 285.8 E(33420): 2.3e-77
Smith-Waterman score: 1951; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272)
10 20 30 40 50 60
pF1KE2 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 HLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 HLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREII
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QHPSAKGNLCPPTNETRKCTVQRKKCQKGERGKKGRERKRKKPNKGESKEAIPDSKSLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 QHPSAKGNLCPPTNETRKCTVQRKKCQKGERGKKGRERKRKKPNKGESKEAIPDSKSLES
190 200 210 220 230 240
250 260 270
pF1KE2 SKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH
::::::::::::::::::::::::::::::::
CCDS51 SKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH
250 260 270
>>CCDS41304.1 RSPO1 gene_id:284654|Hs109|chr1 (263 aa)
initn: 881 init1: 508 opt: 885 Z-score: 692.7 bits: 135.9 E(33420): 3e-32
Smith-Waterman score: 885; 46.0% identity (72.2% similar) in 252 aa overlap (11-257:10-251)
10 20 30 40 50 60
pF1KE2 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR
..:.. . :. . .:.::::. . ::.: :: ::. ::::.:.:.
CCDS41 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPK
10 20 30 40 50
70 80 90 100 110
pF1KE2 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKAD-CDTCFNKNFCTKCKSGFY
::. ::: ..:.:::: ::: ::. .: ::.::: ::: . :..::..::::::: :.:
CCDS41 LFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 LHLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREI
:: :.: :::: : : :::: : ..::.:::.::.::.:: . :::.::.: :.:..
CCDS41 LHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 IQHPSAKGNLCPPTNETRKCTVQRKKCQKGERGKKGRERKRKKPNKG----ESKEAIPDS
.. : . : :.:::.:::.: : .:.. .:: . .:.. :.. ::::: :
CCDS41 LHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGS
180 190 200 210 220 230
240 250 260 270
pF1KE2 KSLESSKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH
. .:...:::...
CCDS41 R----------RRKGQQQQQQQGTVGPLTSAGPA
240 250 260
>>CCDS55591.1 RSPO1 gene_id:284654|Hs109|chr1 (236 aa)
initn: 857 init1: 508 opt: 842 Z-score: 660.6 bits: 129.8 E(33420): 1.8e-30
Smith-Waterman score: 842; 47.6% identity (72.3% similar) in 231 aa overlap (32-257:4-224)
10 20 30 40 50 60
pF1KE2 HLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPRL
:. . ::.: :: ::. ::::.:.:.:
CCDS55 MIFRVSAEGSQACAKGCELCSEVNGCLKCSPKL
10 20 30
70 80 90 100 110 120
pF1KE2 FFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKAD-CDTCFNKNFCTKCKSGFYL
:. ::: ..:.:::: ::: ::. .: ::.::: ::: . :..::..::::::: :.::
CCDS55 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 HLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREII
: :.: :::: : : :::: : ..::.:::.::.::.:: . :::.::.: :.:...
CCDS55 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
100 110 120 130 140 150
190 200 210 220 230
pF1KE2 QHPSAKGNLCPPTNETRKCTVQRKKCQKGERGKKGRERKRKKPNKG----ESKEAIPDSK
. : . : :.:::.:::.: : .:.. .:: . .:.. :.. ::::: :.
CCDS55 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
160 170 180 190 200 210
240 250 260 270
pF1KE2 SLESSKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH
.:...:::...
CCDS55 ----------RRKGQQQQQQQGTVGPLTSAGPA
220 230
>>CCDS6307.1 RSPO2 gene_id:340419|Hs109|chr8 (243 aa)
initn: 598 init1: 280 opt: 825 Z-score: 647.5 bits: 127.4 E(33420): 9.8e-30
Smith-Waterman score: 825; 47.3% identity (73.5% similar) in 226 aa overlap (1-225:1-222)
10 20 30 40 50 60
pF1KE2 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR
:..::.:. .:::: :.: :. .: ::..: . :.: : .:: ::: :. .
CCDS63 MQFRLFSFALIILNCMDYSHCQG-NRWRRSKRASYVSNPICKG-CLSCSKDNGCSRCQQK
10 20 30 40 50
70 80 90 100 110
pF1KE2 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKAD-CDTCFNKNFCTKCKSGFY
::: :.: ::.: : :: :::::::: : ::.:.:..:. . ::.::.:.:::::: :::
CCDS63 LFFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 LHLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREI
:: :.:.:.::.:. ..::::: :::..:. :. :.....::::: : :::.:.:
CCDS63 LHRGRCFDECPDGFAPLEETMECVE--GCEVGHWSEWGTCSRNNRTCGFKWGLETRTRQI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 IQHPSAKGNLCPPTNETRKCTVQRKKCQKGERGKKGRERKRKKPNKGESKEAIPDSKSLE
...: ::: :.:.: . ..: :.: :..:.. :: ..
CCDS63 VKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFL
180 190 200 210 220 230
240 250 260 270
pF1KE2 SSKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH
CCDS63 ATDRANQ
240
>>CCDS42846.1 RSPO4 gene_id:343637|Hs109|chr20 (234 aa)
initn: 619 init1: 431 opt: 667 Z-score: 527.7 bits: 105.2 E(33420): 4.7e-23
Smith-Waterman score: 667; 43.3% identity (69.2% similar) in 201 aa overlap (28-225:22-217)
10 20 30 40 50 60
pF1KE2 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR
::.... ... .: : : ::. ::: .:. :
CCDS42 MRAPLCLLLLVAHAVDMLALNRRKKQVGTGLGGNCTG-CIICSEENGCSTCQQR
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYL
::. ..: :..: : :: .:: ::.: : ..:.: :: : :..::...:: .:: :::
CCDS42 LFLFIRREGIRQYGKCLHDCPPGYFGIRGQEVNRCKKCGATCESCFSQDFCIRCKRQFYL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 HLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREII
. :::: .:: : :...: :: . .::.. :. :::::..::::: : :.::::
CCDS42 YKGKCLPTCPPGTLAHQNTRECQG--ECELGPWGGWSPCTHNGKTCGSAWGLESRVREAG
120 130 140 150 160 170
190 200 210 220 230
pF1KE2 QHPSAKGNLCPPTNETRKCTVQRKKCQKGERG---KKGRERKRKKPNKGESKEAIPDSKS
. .. : .:.::: .:: : :::. ::::. .: . ..
CCDS42 RAGHEEAATCQVLSESRKCPIQRP-CP-GERSPGQKKGRKDRRPRKDRKLDRRLDVRPRQ
180 190 200 210 220
240 250 260 270
pF1KE2 LESSKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH
CCDS42 PGLQP
230
>>CCDS83314.1 RSPO2 gene_id:340419|Hs109|chr8 (176 aa)
initn: 549 init1: 270 opt: 645 Z-score: 512.5 bits: 102.0 E(33420): 3.3e-22
Smith-Waterman score: 645; 49.0% identity (76.4% similar) in 157 aa overlap (70-225:1-155)
40 50 60 70 80 90
pF1KE2 GCQGGCATCSDYNGCLSCKPRLFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCK
:.: : :: :::::::: : ::.:.:..:.
CCDS83 MRQYGECLHSCPSGYYGHRAPDMNRCARCR
10 20 30
100 110 120 130 140 150
pF1KE2 AD-CDTCFNKNFCTKCKSGFYLHLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSP
. ::.::.:.:::::: ::::: :.:.:.::.:. ..::::: :::..:. :.
CCDS83 IENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETMECVE--GCEVGHWSEWGT
40 50 60 70 80
160 170 180 190 200 210
pF1KE2 CTKKGKTCGFKRGTETRVREIIQHPSAKGNLCPPTNETRKCTVQRKKCQKGERGKKGRER
:.....::::: : :::.:.:...: ::: :.:.: . ..: :.: :..:.
CCDS83 CSRNNRTCGFKWGLETRTRQIVKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEK
90 100 110 120 130 140
220 230 240 250 260 270
pF1KE2 KRKKPNKGESKEAIPDSKSLESSKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH
. :: ..
CCDS83 RNKKKKRKLIERAQEQHSVFLATDRANQ
150 160 170
>>CCDS55590.1 RSPO1 gene_id:284654|Hs109|chr1 (200 aa)
initn: 572 init1: 336 opt: 565 Z-score: 451.0 bits: 90.8 E(33420): 8.7e-19
Smith-Waterman score: 565; 52.6% identity (74.8% similar) in 135 aa overlap (11-144:10-144)
10 20 30 40 50 60
pF1KE2 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR
..:.. . :. . .:.::::. . ::.: :: ::. ::::.:.:.
CCDS55 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPK
10 20 30 40 50
70 80 90 100 110
pF1KE2 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKAD-CDTCFNKNFCTKCKSGFY
::. ::: ..:.:::: ::: ::. .: ::.::: ::: . :..::..::::::: :.:
CCDS55 LFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 LHLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREI
:: :.: :::: : : :::: :
CCDS55 LHKGRCYPACPEGSSAANGTMECSSPGQKRRKGGQGRRENANRNLARKESKEAGAGSRRR
120 130 140 150 160 170
>>CCDS64953.1 RSPO2 gene_id:340419|Hs109|chr8 (179 aa)
initn: 600 init1: 270 opt: 494 Z-score: 397.6 bits: 80.7 E(33420): 8.1e-16
Smith-Waterman score: 494; 45.7% identity (76.0% similar) in 129 aa overlap (98-225:33-158)
70 80 90 100 110 120
pF1KE2 IGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKAD-CDTCFNKNFCTKCKSGFYLHLGKCL
:. . ::.::.:.:::::: ::::: :.:.
CCDS64 FRLFSFALIILNCMDYSHCQGNRWRRSKRGCRIENCDSCFSKDFCTKCKVGFYLHRGRCF
10 20 30 40 50 60
130 140 150 160 170 180
pF1KE2 DNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREIIQHPSAK
:.::.:. ..:::::. :::..:. :. :.....::::: : :::.:.:...:
CCDS64 DECPDGFAPLEETMECVG---CEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIVKKPVKD
70 80 90 100 110
190 200 210 220 230 240
pF1KE2 GNLCPPTNETRKCTVQRKKCQKGERGKKGRERKRKKPNKGESKEAIPDSKSLESSKEIPE
::: :.:.: . ..: :.: :..:.. :: ..
CCDS64 TILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLATDRANQ
120 130 140 150 160 170
250 260 270
pF1KE2 QRENKQQQKKRKVQDKQKSVSVSTVH
>>CCDS42845.1 RSPO4 gene_id:343637|Hs109|chr20 (172 aa)
initn: 451 init1: 431 opt: 448 Z-score: 362.9 bits: 74.2 E(33420): 7e-14
Smith-Waterman score: 448; 45.2% identity (73.0% similar) in 115 aa overlap (28-142:22-135)
10 20 30 40 50 60
pF1KE2 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR
::.... ... .: : : ::. ::: .:. :
CCDS42 MRAPLCLLLLVAHAVDMLALNRRKKQVGTGLGGNCTG-CIICSEENGCSTCQQR
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYL
::. ..: :..: : :: .:: ::.: : ..:.: :: : :..::...:: .:: :::
CCDS42 LFLFIRREGIRQYGKCLHDCPPGYFGIRGQEVNRCKKCGATCESCFSQDFCIRCKRQFYL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 HLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREII
. :::: .:: : :...: ::
CCDS42 YKGKCLPTCPPGTLAHQNTRECQERSPGQKKGRKDRRPRKDRKLDRRLDVRPRQPGLQP
120 130 140 150 160 170
272 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Jun 30 14:57:09 2019 done: Sun Jun 30 14:57:09 2019
Total Scan time: 1.150 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]