Result of FASTA (ccds) for
pF1KE2729
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2729, 465 aa
1>>>pF1KE2729 465 - 465 aa - 465 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0840+/-0.00105; mu= -5.7599+/- 0.061
mean_var=324.2568+/-73.467, 0's: 0 Z-trim(110.8): 122 B-trim: 0 in 0/53
Lambda= 0.071225
statistics sampled from 11956 (12067) to 11956 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.361), width: 16
Scan time: 1.560
The best scores are: opt bits E(33420)
CCDS538.1 MKNK1 gene_id:8569|Hs109|chr1 ( 465) 3118 334.6 1.3e-91
CCDS44134.1 MKNK1 gene_id:8569|Hs109|chr1 ( 424) 1794 198.6 1.1e-50
CCDS12080.1 MKNK2 gene_id:2872|Hs109|chr19 ( 465) 1322 150.1 4.7e-36
CCDS30705.1 MKNK1 gene_id:8569|Hs109|chr1 ( 347) 1222 139.7 4.8e-33
CCDS12079.1 MKNK2 gene_id:2872|Hs109|chr19 ( 414) 1147 132.1 1.1e-30
>>CCDS538.1 MKNK1 gene_id:8569|Hs109|chr1 (465 aa)
initn: 3118 init1: 3118 opt: 3118 Z-score: 1758.3 bits: 334.6 E(33420): 1.3e-91
Smith-Waterman score: 3118; 100.0% identity (100.0% similar) in 465 aa overlap (1-465:1-465)
10 20 30 40 50 60
pF1KE2 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 GLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL
370 380 390 400 410 420
430 440 450 460
pF1KE2 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL
:::::::::::::::::::::::::::::::::::::::::::::
CCDS53 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL
430 440 450 460
>>CCDS44134.1 MKNK1 gene_id:8569|Hs109|chr1 (424 aa)
initn: 1794 init1: 1794 opt: 1794 Z-score: 1023.5 bits: 198.6 E(33420): 1.1e-50
Smith-Waterman score: 2755; 91.2% identity (91.2% similar) in 465 aa overlap (1-465:1-424)
10 20 30 40 50 60
pF1KE2 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPS
::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTK----------------
130 140 150 160
190 200 210 220 230 240
pF1KE2 GLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK
:::::::::::::::::::::::::::::::::::
CCDS44 -------------------------GIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK
170 180 190
250 260 270 280 290 300
pF1KE2 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE2 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE2 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL
320 330 340 350 360 370
430 440 450 460
pF1KE2 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL
:::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGEDRSPPTAL
380 390 400 410 420
>>CCDS12080.1 MKNK2 gene_id:2872|Hs109|chr19 (465 aa)
initn: 1328 init1: 1272 opt: 1322 Z-score: 760.9 bits: 150.1 E(33420): 4.7e-36
Smith-Waterman score: 1926; 65.7% identity (80.8% similar) in 452 aa overlap (9-451:45-451)
10 20 30
pF1KE2 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATD
.: .: .:.:. : :. .: :::.::::::
CCDS12 SFKGQNPFELAFSLDQPDHGDSDFGLQCSARP-DMPASQPIDIPDAKKRGKKKKRGRATD
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 SLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETL
:. :.:::.:.: ..:::::.:.:: ..: ...:::::::::: :: ::::::::: :
CCDS12 SFSGRFEDVYQLQEDVLGEGAHARVQTCINLITSQEYAVKIIEKQPGHIRSRVFREVEML
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 YQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAAL
:::::..:.::::::::.. ::::::::..:::::.::.:..:::: ::: ::.:::.::
CCDS12 YQCQGHRNVLELIEFFEEEDRFYLVFEKMRGGSILSHIHKRRHFNELEASVVVQDVASAL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 DFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENIL
::::.: :::::::::::::
CCDS12 DFLHNK-----------------------------------------GIAHRDLKPENIL
200 210
220 230 240 250 260 270
pF1KE2 CESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFY
:: :..::::::::::::::.:::..:.::.:::: :::::::::::::::.:...:..:
CCDS12 CEHPNQVSPVKICDFDLGSGIKLNGDCSPISTPELLTPCGSAEYMAPEVVEAFSEEASIY
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE2 DKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDK
:::::::::::.:::.:::::::::.::.::::::::.: .::: :::::::::::::::
CCDS12 DKRCDLWSLGVILYILLSGYPPFVGRCGSDCGWDRGEACPACQNMLFESIQEGKYEFPDK
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE2 DWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDL
:::::: :::::::::::::::::::::::::::::: :::. ::::.:::::: . ::
CCDS12 DWAHISCAAKDLISKLLVRDAKQRLSAAQVLQHPWVQGCAPENTLPTPMVLQRNSCAKDL
340 350 360 370 380 390
400 410 420 430 440
pF1KE2 TLFAAEAIALNRQLSQHEENELAEEPEALADGL---------CSMKLSPPCKSRLARRRA
: :::::::.::::.::.:. :::: :: ..: : ..:::: .:.::.::
CCDS12 TSFAAEAIAMNRQLAQHDED-LAEE-EAAGQGQPVLVRATSRC-LQLSPPSQSKLAQRRQ
400 410 420 430 440
450 460
pF1KE2 LAQAGRGEDRSPPTAL
:
CCDS12 RASLSSAPVVLVGDHA
450 460
>>CCDS30705.1 MKNK1 gene_id:8569|Hs109|chr1 (347 aa)
initn: 2261 init1: 1218 opt: 1222 Z-score: 707.0 bits: 139.7 E(33420): 4.8e-33
Smith-Waterman score: 2183; 88.0% identity (88.7% similar) in 382 aa overlap (1-382:1-341)
10 20 30 40 50 60
pF1KE2 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 AKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPS
::::::::::::::::::::::::::::::::::::::::::::
CCDS30 YLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTK----------------
130 140 150 160
190 200 210 220 230 240
pF1KE2 GLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK
:::::::::::::::::::::::::::::::::::
CCDS30 -------------------------GIAHRDLKPENILCESPEKVSPVKICDFDLGSGMK
170 180 190
250 260 270 280 290 300
pF1KE2 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 LNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPP
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE2 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 FVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAK
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE2 QRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDLTLFAAEAIALNRQLSQHEENEL
::::::::::::::::. ..:
CCDS30 QRLSAAQVLQHPWVQGEQQHNGPDALRS
320 330 340
>>CCDS12079.1 MKNK2 gene_id:2872|Hs109|chr19 (414 aa)
initn: 1785 init1: 1147 opt: 1147 Z-score: 664.4 bits: 132.1 E(33420): 1.1e-30
Smith-Waterman score: 1751; 67.6% identity (82.4% similar) in 386 aa overlap (9-394:45-388)
10 20 30
pF1KE2 MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATD
.: .: .:.:. : :. .: :::.::::::
CCDS12 SFKGQNPFELAFSLDQPDHGDSDFGLQCSARP-DMPASQPIDIPDAKKRGKKKKRGRATD
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 SLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETL
:. :.:::.:.: ..:::::.:.:: ..: ...:::::::::: :: ::::::::: :
CCDS12 SFSGRFEDVYQLQEDVLGEGAHARVQTCINLITSQEYAVKIIEKQPGHIRSRVFREVEML
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 YQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAAL
:::::..:.::::::::.. ::::::::..:::::.::.:..:::: ::: ::.:::.::
CCDS12 YQCQGHRNVLELIEFFEEEDRFYLVFEKMRGGSILSHIHKRRHFNELEASVVVQDVASAL
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 DFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENIL
::::.: :::::::::::::
CCDS12 DFLHNK-----------------------------------------GIAHRDLKPENIL
200 210
220 230 240 250 260 270
pF1KE2 CESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGSAEYMAPEVVEVFTDQATFY
:: :..::::::::::::::.:::..:.::.:::: :::::::::::::::.:...:..:
CCDS12 CEHPNQVSPVKICDFDLGSGIKLNGDCSPISTPELLTPCGSAEYMAPEVVEAFSEEASIY
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE2 DKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRVCQNKLFESIQEGKYEFPDK
:::::::::::.:::.:::::::::.::.::::::::.: .::: :::::::::::::::
CCDS12 DKRCDLWSLGVILYILLSGYPPFVGRCGSDCGWDRGEACPACQNMLFESIQEGKYEFPDK
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE2 DWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAPEKGLPTPQVLQRNSSTMDL
:::::: :::::::::::::::::::::::::::::: :::. ::::.:::: .:
CCDS12 DWAHISCAAKDLISKLLVRDAKQRLSAAQVLQHPWVQGCAPENTLPTPMVLQRWDSHFLL
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE2 TLFAAEAIALNRQLSQHEENELAEEPEALADGLCSMKLSPPCKSRLARRRALAQAGRGED
CCDS12 PPHPCRIHVRPGGLVRTVTVNE
400 410
465 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Oct 2 18:31:12 2018 done: Tue Oct 2 18:31:13 2018
Total Scan time: 1.560 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]