Result of FASTA (omim) for
pF1KE2709
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2709, 1647 aa
1>>>pF1KE2709 1647 - 1647 aa - 1647 aa
Library: /omim/omim.rfq.tfa
63842531 residues in 89799 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.7719+/-0.000543; mu= -25.1870+/- 0.034
mean_var=884.0521+/-186.147, 0's: 0 Z-trim(124.9): 349 B-trim: 2134 in 1/59
Lambda= 0.043136
statistics sampled from 48323 (48748) to 48323 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.784), E-opt: 0.2 (0.543), width: 16
Scan time: 10.530
The best scores are: opt bits E(89799)
NP_003063 (OMIM: 603254,613325,614609) transcripti (1647) 11097 707.5 2.6e-202
NP_001122316 (OMIM: 603254,613325,614609) transcri (1647) 11097 707.5 2.6e-202
XP_016882650 (OMIM: 603254,613325,614609) PREDICTE (1650) 11081 706.5 5.1e-202
XP_016882652 (OMIM: 603254,613325,614609) PREDICTE (1646) 11080 706.4 5.3e-202
XP_016882651 (OMIM: 603254,613325,614609) PREDICTE (1646) 10137 647.8 2.5e-184
XP_016882653 (OMIM: 603254,613325,614609) PREDICTE (1645) 10120 646.7 5.1e-184
XP_016882649 (OMIM: 603254,613325,614609) PREDICTE (1678) 9489 607.4 3.4e-172
XP_011526500 (OMIM: 603254,613325,614609) PREDICTE (1679) 9489 607.4 3.4e-172
XP_006722909 (OMIM: 603254,613325,614609) PREDICTE (1679) 9489 607.4 3.4e-172
NP_001122321 (OMIM: 603254,613325,614609) transcri (1679) 9489 607.4 3.4e-172
XP_006722908 (OMIM: 603254,613325,614609) PREDICTE (1679) 9489 607.4 3.4e-172
XP_016882655 (OMIM: 603254,613325,614609) PREDICTE (1616) 8576 550.6 4.2e-155
NP_001122318 (OMIM: 603254,613325,614609) transcri (1616) 8576 550.6 4.2e-155
XP_016882657 (OMIM: 603254,613325,614609) PREDICTE (1613) 8568 550.1 6e-155
NP_001122320 (OMIM: 603254,613325,614609) transcri (1613) 8568 550.1 6e-155
NP_001122317 (OMIM: 603254,613325,614609) transcri (1617) 8565 549.9 6.8e-155
XP_016882654 (OMIM: 603254,613325,614609) PREDICTE (1617) 8565 549.9 6.8e-155
XP_016882656 (OMIM: 603254,613325,614609) PREDICTE (1614) 8563 549.8 7.4e-155
NP_001122319 (OMIM: 603254,613325,614609) transcri (1614) 8563 549.8 7.4e-155
NP_620614 (OMIM: 600014,601358) probable global tr (1572) 5584 364.4 4.7e-99
NP_001276325 (OMIM: 600014,601358) probable global (1590) 5584 364.4 4.7e-99
NP_003061 (OMIM: 600014,601358) probable global tr (1590) 5584 364.4 4.7e-99
NP_001276326 (OMIM: 600014,601358) probable global (1514) 2006 141.7 4.9e-32
XP_011515862 (OMIM: 189960,214800,608892,612370) P (1621) 1124 86.9 1.7e-15
XP_016869102 (OMIM: 189960,214800,608892,612370) P (2996) 1124 87.1 2.7e-15
NP_060250 (OMIM: 189960,214800,608892,612370) chro (2997) 1124 87.1 2.7e-15
XP_011515857 (OMIM: 189960,214800,608892,612370) P (3026) 1124 87.1 2.7e-15
XP_016869101 (OMIM: 189960,214800,608892,612370) P (3027) 1124 87.1 2.7e-15
XP_011515855 (OMIM: 189960,214800,608892,612370) P (3027) 1124 87.1 2.7e-15
XP_011515856 (OMIM: 189960,214800,608892,612370) P (3027) 1124 87.1 2.7e-15
XP_016879559 (OMIM: 602120) PREDICTED: chromodomai (2050) 1060 83.0 3.2e-14
XP_016879551 (OMIM: 602120) PREDICTED: chromodomai (2105) 1060 83.0 3.3e-14
XP_016874223 (OMIM: 603277,617159) PREDICTED: chro (1892) 1051 82.4 4.4e-14
XP_016874222 (OMIM: 603277,617159) PREDICTED: chro (1893) 1051 82.4 4.4e-14
XP_016874221 (OMIM: 603277,617159) PREDICTED: chro (1895) 1051 82.4 4.4e-14
XP_016874220 (OMIM: 603277,617159) PREDICTED: chro (1899) 1051 82.4 4.5e-14
XP_016874219 (OMIM: 603277,617159) PREDICTED: chro (1900) 1051 82.4 4.5e-14
XP_006719025 (OMIM: 603277,617159) PREDICTED: chro (1902) 1051 82.4 4.5e-14
XP_005253725 (OMIM: 603277,617159) PREDICTED: chro (1905) 1051 82.4 4.5e-14
NP_001284482 (OMIM: 603277,617159) chromodomain-he (1905) 1051 82.4 4.5e-14
XP_016874218 (OMIM: 603277,617159) PREDICTED: chro (1906) 1051 82.4 4.5e-14
XP_006719024 (OMIM: 603277,617159) PREDICTED: chro (1908) 1051 82.4 4.5e-14
NP_001264 (OMIM: 603277,617159) chromodomain-helic (1912) 1051 82.4 4.5e-14
XP_016874215 (OMIM: 603277,617159) PREDICTED: chro (1913) 1051 82.4 4.5e-14
XP_016874214 (OMIM: 603277,617159) PREDICTED: chro (1914) 1051 82.4 4.5e-14
XP_006719022 (OMIM: 603277,617159) PREDICTED: chro (1915) 1051 82.4 4.5e-14
XP_016879550 (OMIM: 602120) PREDICTED: chromodomai (2109) 1049 82.3 5.2e-14
NP_056372 (OMIM: 610771) chromodomain-helicase-DNA (1954) 1045 82.0 5.9e-14
NP_001276327 (OMIM: 600014,601358) probable global ( 248) 1010 79.0 6e-14
XP_016874217 (OMIM: 603277,617159) PREDICTED: chro (1911) 1044 82.0 6e-14
>>NP_003063 (OMIM: 603254,613325,614609) transcription a (1647 aa)
initn: 11097 init1: 11097 opt: 11097 Z-score: 3753.7 bits: 707.5 E(89799): 2.6e-202
Smith-Waterman score: 11097; 100.0% identity (100.0% similar) in 1647 aa overlap (1-1647:1-1647)
10 20 30 40 50 60
pF1KE2 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 KKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYEL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 IRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSV
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS
1570 1580 1590 1600 1610 1620
1630 1640
pF1KE2 RAKPVVSDDDSEEEQEEDRSGSGSEED
:::::::::::::::::::::::::::
NP_003 RAKPVVSDDDSEEEQEEDRSGSGSEED
1630 1640
>>NP_001122316 (OMIM: 603254,613325,614609) transcriptio (1647 aa)
initn: 11097 init1: 11097 opt: 11097 Z-score: 3753.7 bits: 707.5 E(89799): 2.6e-202
Smith-Waterman score: 11097; 100.0% identity (100.0% similar) in 1647 aa overlap (1-1647:1-1647)
10 20 30 40 50 60
pF1KE2 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 KKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYEL
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 IRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSV
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS
1570 1580 1590 1600 1610 1620
1630 1640
pF1KE2 RAKPVVSDDDSEEEQEEDRSGSGSEED
:::::::::::::::::::::::::::
NP_001 RAKPVVSDDDSEEEQEEDRSGSGSEED
1630 1640
>>XP_016882650 (OMIM: 603254,613325,614609) PREDICTED: t (1650 aa)
initn: 9498 init1: 9498 opt: 11081 Z-score: 3748.3 bits: 706.5 E(89799): 5.1e-202
Smith-Waterman score: 11081; 99.8% identity (99.8% similar) in 1650 aa overlap (1-1647:1-1650)
10 20 30 40 50 60
pF1KE2 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE2 DSLTEKQWLK---AIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDES
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSLTEKQWLKTLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDES
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE2 KKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKQKKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEY
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE2 YELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YELIRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVF
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KE2 TSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSVRQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPS
1570 1580 1590 1600 1610 1620
1620 1630 1640
pF1KE2 RGSRAKPVVSDDDSEEEQEEDRSGSGSEED
::::::::::::::::::::::::::::::
XP_016 RGSRAKPVVSDDDSEEEQEEDRSGSGSEED
1630 1640 1650
>>XP_016882652 (OMIM: 603254,613325,614609) PREDICTED: t (1646 aa)
initn: 10006 init1: 10006 opt: 11080 Z-score: 3748.0 bits: 706.4 E(89799): 5.3e-202
Smith-Waterman score: 11080; 99.9% identity (99.9% similar) in 1647 aa overlap (1-1647:1-1646)
10 20 30 40 50 60
pF1KE2 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 DSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 KKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYEL
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_016 KKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSS-GRQLSEVFIQLPSRKELPEYYEL
1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE2 IRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSV
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE2 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS
1560 1570 1580 1590 1600 1610
1630 1640
pF1KE2 RAKPVVSDDDSEEEQEEDRSGSGSEED
:::::::::::::::::::::::::::
XP_016 RAKPVVSDDDSEEEQEEDRSGSGSEED
1620 1630 1640
>>XP_016882651 (OMIM: 603254,613325,614609) PREDICTED: t (1646 aa)
initn: 10180 init1: 8553 opt: 10137 Z-score: 3430.8 bits: 647.8 E(89799): 2.5e-184
Smith-Waterman score: 10712; 96.1% identity (96.1% similar) in 1679 aa overlap (1-1647:1-1646)
10 20 30 40 50 60
pF1KE2 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDE--
1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE2 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
:::::::::::::::::::::::::::::
XP_016 -------------------------------EEDEVPDDETVNQMIARHEEEFDLFMRMD
1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KE2 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
1290 1300 1310 1320 1330 1340
1390 1400
pF1KE2 DSLTEKQWLK--------------------------------AIEEGTLEEIEEEVRQKK
:::::::::: ::::::::::::::::::
XP_016 DSLTEKQWLKKITGKDIHDTASSVARGLQFQRGLQFCTRASKAIEEGTLEEIEEEVRQKK
1350 1360 1370 1380 1390 1400
1410 1420 1430 1440 1450 1460
pF1KE2 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
1410 1420 1430 1440 1450 1460
1470 1480 1490 1500 1510 1520
pF1KE2 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
1470 1480 1490 1500 1510 1520
1530 1540 1550 1560 1570 1580
pF1KE2 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
1530 1540 1550 1560 1570 1580
1590 1600 1610 1620 1630 1640
pF1KE2 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
1590 1600 1610 1620 1630 1640
>>XP_016882653 (OMIM: 603254,613325,614609) PREDICTED: t (1645 aa)
initn: 9635 init1: 8553 opt: 10120 Z-score: 3425.1 bits: 646.7 E(89799): 5.1e-184
Smith-Waterman score: 10695; 96.1% identity (96.1% similar) in 1679 aa overlap (1-1647:1-1645)
10 20 30 40 50 60
pF1KE2 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDE--
1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE2 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
:::::::::::::::::::::::::::::
XP_016 -------------------------------EEDEVPDDETVNQMIARHEEEFDLFMRMD
1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KE2 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
1290 1300 1310 1320 1330 1340
1390 1400
pF1KE2 DSLTEKQWLK--------------------------------AIEEGTLEEIEEEVRQKK
:::::::::: ::::::::::::::::::
XP_016 DSLTEKQWLKKITGKDIHDTASSVARGLQFQRGLQFCTRASKAIEEGTLEEIEEEVRQKK
1350 1360 1370 1380 1390 1400
1410 1420 1430 1440 1450 1460
pF1KE2 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
1410 1420 1430 1440 1450 1460
1470 1480 1490 1500 1510 1520
pF1KE2 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIKYKDSS-GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
1470 1480 1490 1500 1510 1520
1530 1540 1550 1560 1570 1580
pF1KE2 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
1530 1540 1550 1560 1570 1580
1590 1600 1610 1620 1630 1640
pF1KE2 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
1590 1600 1610 1620 1630 1640
>>XP_016882649 (OMIM: 603254,613325,614609) PREDICTED: t (1678 aa)
initn: 10555 init1: 9473 opt: 9489 Z-score: 3212.8 bits: 607.4 E(89799): 3.4e-172
Smith-Waterman score: 11006; 98.0% identity (98.0% similar) in 1679 aa overlap (1-1647:1-1678)
10 20 30 40 50 60
pF1KE2 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
1330 1340 1350 1360 1370 1380
1390 1400
pF1KE2 DSLTEKQWLK--------------------------------AIEEGTLEEIEEEVRQKK
:::::::::: ::::::::::::::::::
XP_016 DSLTEKQWLKKITGKDIHDTASSVARGLQFQRGLQFCTRASKAIEEGTLEEIEEEVRQKK
1390 1400 1410 1420 1430 1440
1410 1420 1430 1440 1450 1460
pF1KE2 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
1450 1460 1470 1480 1490 1500
1470 1480 1490 1500 1510 1520
pF1KE2 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIKYKDSS-GRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
1510 1520 1530 1540 1550
1530 1540 1550 1560 1570 1580
pF1KE2 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
1560 1570 1580 1590 1600 1610
1590 1600 1610 1620 1630 1640
pF1KE2 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
1620 1630 1640 1650 1660 1670
>>XP_011526500 (OMIM: 603254,613325,614609) PREDICTED: t (1679 aa)
initn: 9696 init1: 9466 opt: 9489 Z-score: 3212.7 bits: 607.4 E(89799): 3.4e-172
Smith-Waterman score: 11023; 98.1% identity (98.1% similar) in 1679 aa overlap (1-1647:1-1679)
10 20 30 40 50 60
pF1KE2 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
1330 1340 1350 1360 1370 1380
1390 1400
pF1KE2 DSLTEKQWLK--------------------------------AIEEGTLEEIEEEVRQKK
:::::::::: ::::::::::::::::::
XP_011 DSLTEKQWLKKITGKDIHDTASSVARGLQFQRGLQFCTRASKAIEEGTLEEIEEEVRQKK
1390 1400 1410 1420 1430 1440
1410 1420 1430 1440 1450 1460
pF1KE2 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
1450 1460 1470 1480 1490 1500
1470 1480 1490 1500 1510 1520
pF1KE2 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
1510 1520 1530 1540 1550 1560
1530 1540 1550 1560 1570 1580
pF1KE2 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
1570 1580 1590 1600 1610 1620
1590 1600 1610 1620 1630 1640
pF1KE2 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
1630 1640 1650 1660 1670
>>XP_006722909 (OMIM: 603254,613325,614609) PREDICTED: t (1679 aa)
initn: 9696 init1: 9466 opt: 9489 Z-score: 3212.7 bits: 607.4 E(89799): 3.4e-172
Smith-Waterman score: 11023; 98.1% identity (98.1% similar) in 1679 aa overlap (1-1647:1-1679)
10 20 30 40 50 60
pF1KE2 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
1330 1340 1350 1360 1370 1380
1390 1400
pF1KE2 DSLTEKQWLK--------------------------------AIEEGTLEEIEEEVRQKK
:::::::::: ::::::::::::::::::
XP_006 DSLTEKQWLKKITGKDIHDTASSVARGLQFQRGLQFCTRASKAIEEGTLEEIEEEVRQKK
1390 1400 1410 1420 1430 1440
1410 1420 1430 1440 1450 1460
pF1KE2 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
1450 1460 1470 1480 1490 1500
1470 1480 1490 1500 1510 1520
pF1KE2 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
1510 1520 1530 1540 1550 1560
1530 1540 1550 1560 1570 1580
pF1KE2 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
1570 1580 1590 1600 1610 1620
1590 1600 1610 1620 1630 1640
pF1KE2 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
1630 1640 1650 1660 1670
>>NP_001122321 (OMIM: 603254,613325,614609) transcriptio (1679 aa)
initn: 9696 init1: 9466 opt: 9489 Z-score: 3212.7 bits: 607.4 E(89799): 3.4e-172
Smith-Waterman score: 11023; 98.1% identity (98.1% similar) in 1679 aa overlap (1-1647:1-1679)
10 20 30 40 50 60
pF1KE2 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIDQKKDKRLAYLLQQTDEYVANLTELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
1330 1340 1350 1360 1370 1380
1390 1400
pF1KE2 DSLTEKQWLK--------------------------------AIEEGTLEEIEEEVRQKK
:::::::::: ::::::::::::::::::
NP_001 DSLTEKQWLKKITGKDIHDTASSVARGLQFQRGLQFCTRASKAIEEGTLEEIEEEVRQKK
1390 1400 1410 1420 1430 1440
1410 1420 1430 1440 1450 1460
pF1KE2 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA
1450 1460 1470 1480 1490 1500
1470 1480 1490 1500 1510 1520
pF1KE2 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD
1510 1520 1530 1540 1550 1560
1530 1540 1550 1560 1570 1580
pF1KE2 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGSES
1570 1580 1590 1600 1610 1620
1590 1600 1610 1620 1630 1640
pF1KE2 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGSGSEED
1630 1640 1650 1660 1670
1647 residues in 1 query sequences
63842531 residues in 89799 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Feb 8 18:23:23 2018 done: Thu Feb 8 18:23:25 2018
Total Scan time: 10.530 Total Display time: 0.680
Function used was FASTA [36.3.4 Apr, 2011]