Result of FASTA (omim) for
pF1KE2695
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2695, 2339 aa
1>>>pF1KE2695 2339 - 2339 aa - 2339 aa
Library: /omim/omim.rfq.tfa
62246620 residues in 87639 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.3802+/-0.000503; mu= 4.8773+/- 0.032
mean_var=376.2585+/-76.667, 0's: 0 Z-trim(119.0): 275 B-trim: 0 in 0/58
Lambda= 0.066120
statistics sampled from 32767 (33042) to 32767 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.377), width: 16
Scan time: 23.660
The best scores are: opt bits E(87639)
NP_000709 (OMIM: 601012,614860) voltage-dependent (2339) 15721 1516.1 0
XP_016870606 (OMIM: 601012,614860) PREDICTED: volt (2340) 15709 1515.0 0
XP_016870604 (OMIM: 601012,614860) PREDICTED: volt (2343) 15703 1514.4 0
XP_016870607 (OMIM: 601012,614860) PREDICTED: volt (2338) 15702 1514.3 0
XP_016870609 (OMIM: 601012,614860) PREDICTED: volt (2337) 15696 1513.7 0
XP_011517293 (OMIM: 601012,614860) PREDICTED: volt (2344) 15691 1513.3 0
XP_011517296 (OMIM: 601012,614860) PREDICTED: volt (2338) 15684 1512.6 0
XP_011517295 (OMIM: 601012,614860) PREDICTED: volt (2341) 15678 1512.0 0
XP_011517294 (OMIM: 601012,614860) PREDICTED: volt (2343) 15672 1511.4 0
XP_016870605 (OMIM: 601012,614860) PREDICTED: volt (2342) 15666 1510.9 0
NP_001230741 (OMIM: 601012,614860) voltage-depende (2237) 14545 1403.9 0
XP_016870608 (OMIM: 601012,614860) PREDICTED: volt (1745) 11593 1122.2 0
XP_016857736 (OMIM: 601013) PREDICTED: voltage-dep (2439) 7112 694.9 3.2e-198
NP_001192223 (OMIM: 601013) voltage-dependent R-ty (2251) 7061 690.0 8.9e-197
XP_016857739 (OMIM: 601013) PREDICTED: voltage-dep (2396) 7061 690.0 9.3e-197
XP_016857737 (OMIM: 601013) PREDICTED: voltage-dep (2436) 4990 492.5 2.8e-137
NP_001120693 (OMIM: 108500,141500,183086,601011,61 (2261) 4580 453.4 1.6e-125
NP_001120694 (OMIM: 108500,141500,183086,601011,61 (2506) 4512 446.9 1.5e-123
XP_016857735 (OMIM: 601013) PREDICTED: voltage-dep (2454) 3818 380.7 1.3e-103
XP_016857734 (OMIM: 601013) PREDICTED: voltage-dep (2454) 3804 379.4 3.2e-103
NP_000712 (OMIM: 601013) voltage-dependent R-type (2270) 3766 375.7 3.7e-102
NP_001192222 (OMIM: 601013) voltage-dependent R-ty (2313) 3766 375.7 3.8e-102
XP_016857738 (OMIM: 601013) PREDICTED: voltage-dep (2415) 3766 375.7 3.9e-102
XP_016857732 (OMIM: 601013) PREDICTED: voltage-dep (2458) 3766 375.7 3.9e-102
XP_016857740 (OMIM: 601013) PREDICTED: voltage-dep (2458) 3766 375.7 3.9e-102
XP_016857733 (OMIM: 601013) PREDICTED: voltage-dep (2458) 3766 375.7 3.9e-102
NP_075461 (OMIM: 108500,141500,183086,601011,61710 (2512) 3698 369.3 3.6e-100
NP_001167551 (OMIM: 108500,141500,183086,601011,61 (2263) 3510 351.3 8.3e-95
NP_000059 (OMIM: 108500,141500,183086,601011,61710 (2266) 3510 351.3 8.3e-95
NP_001123318 (OMIM: 114205,601005,611875) voltage- (2127) 2636 267.9 1e-69
XP_016875441 (OMIM: 114205,601005,611875) PREDICTE (2183) 2636 267.9 1e-69
NP_001161097 (OMIM: 114205,601005,611875) voltage- (2198) 2629 267.2 1.6e-69
XP_016875421 (OMIM: 114205,601005,611875) PREDICTE (2254) 2629 267.2 1.6e-69
XP_005265505 (OMIM: 114206,614896,615474) PREDICTE (2146) 2620 266.4 2.9e-69
XP_011532398 (OMIM: 114206,614896,615474) PREDICTE (2183) 2620 266.4 2.9e-69
XP_016862634 (OMIM: 114206,614896,615474) PREDICTE (2203) 2620 266.4 2.9e-69
NP_001122311 (OMIM: 114206,614896,615474) voltage- (2137) 2603 264.7 8.9e-69
XP_011542285 (OMIM: 300071,300110,300476,300600) P (1905) 2596 264.0 1.3e-68
XP_005245535 (OMIM: 114208,170400,188580,601887) P (1854) 2535 258.2 7.2e-67
NP_001123311 (OMIM: 114205,601005,611875) voltage- (2144) 2500 254.9 8.1e-66
XP_016875430 (OMIM: 114205,601005,611875) PREDICTE (2200) 2500 254.9 8.2e-66
NP_001123310 (OMIM: 114205,601005,611875) voltage- (2146) 2498 254.7 9.2e-66
XP_016875429 (OMIM: 114205,601005,611875) PREDICTE (2202) 2498 254.7 9.4e-66
NP_001123309 (OMIM: 114205,601005,611875) voltage- (2146) 2493 254.2 1.3e-65
XP_016885325 (OMIM: 300071,300110,300476,300600) P (1027) 2329 238.3 4e-61
NP_001243719 (OMIM: 300071,300110,300476,300600) v (1912) 2031 210.1 2.2e-52
NP_001243718 (OMIM: 300071,300110,300476,300600) v (1966) 2031 210.1 2.2e-52
NP_005174 (OMIM: 300071,300110,300476,300600) volt (1977) 2031 210.1 2.2e-52
XP_016862632 (OMIM: 114206,614896,615474) PREDICTE (2218) 1388 148.9 7e-34
XP_016862633 (OMIM: 114206,614896,615474) PREDICTE (2218) 1388 148.9 7e-34
>>NP_000709 (OMIM: 601012,614860) voltage-dependent N-ty (2339 aa)
initn: 15721 init1: 15721 opt: 15721 Z-score: 8118.3 bits: 1516.1 E(87639): 0
Smith-Waterman score: 15721; 100.0% identity (100.0% similar) in 2339 aa overlap (1-2339:1-2339)
10 20 30 40 50 60
pF1KE2 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 YFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 RASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 APEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 APEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 EARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 GPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 QPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 PVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 RFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 KMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 TIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELER
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 DCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 EQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACI
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 DFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 LMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETNN
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 FINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQV
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 FGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECG
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 SDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIR
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 TALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMI
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 FDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSI
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 TRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPD
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 RPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGP
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 HPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE2 PAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330
pF1KE2 EEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
2290 2300 2310 2320 2330
>>XP_016870606 (OMIM: 601012,614860) PREDICTED: voltage- (2340 aa)
initn: 12908 init1: 12908 opt: 15709 Z-score: 8112.1 bits: 1515.0 E(87639): 0
Smith-Waterman score: 15709; 100.0% identity (100.0% similar) in 2340 aa overlap (1-2339:1-2340)
10 20 30 40 50 60
pF1KE2 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLD-VLKRA
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDAVLKRA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 LRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE2 EAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE2 PEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE2 GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRN
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE2 HQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVH
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE2 IPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLL
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE2 RRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMV
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE2 IKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPL
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE2 KTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELE
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE2 RDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATY
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE2 EEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERAC
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE2 IDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEY
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE2 ELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETN
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KE2 NFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQ
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KE2 VFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATEC
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KE2 GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPA
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KE2 ACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALI
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KE2 RTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KE2 IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTS
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KE2 LSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQS
1930 1940 1950 1960 1970 1980
1980 1990 2000 2010 2020 2030
pF1KE2 ITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTP
1990 2000 2010 2020 2030 2040
2040 2050 2060 2070 2080 2090
pF1KE2 DRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCR
2050 2060 2070 2080 2090 2100
2100 2110 2120 2130 2140 2150
pF1KE2 RERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPG
2110 2120 2130 2140 2150 2160
2160 2170 2180 2190 2200 2210
pF1KE2 PHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTS
2170 2180 2190 2200 2210 2220
2220 2230 2240 2250 2260 2270
pF1KE2 LPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLT
2230 2240 2250 2260 2270 2280
2280 2290 2300 2310 2320 2330
pF1KE2 FEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
2290 2300 2310 2320 2330 2340
>>XP_016870604 (OMIM: 601012,614860) PREDICTED: voltage- (2343 aa)
initn: 8278 init1: 8278 opt: 15703 Z-score: 8109.0 bits: 1514.4 E(87639): 0
Smith-Waterman score: 15703; 99.8% identity (99.8% similar) in 2343 aa overlap (1-2339:1-2343)
10 20 30 40 50 60
pF1KE2 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 YFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 RASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 APEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 EARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 GPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 QPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 PVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 RFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250
pF1KE2 KMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFS----GSKGKDINTIKSLRVLRVL
::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_016 KMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSSFVGGSKGKDINTIKSLRVLRVL
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE2 RPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESK
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE2 ELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVD
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE2 ATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNE
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE2 RACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAP
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE2 YEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIA
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KE2 ETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KE2 GMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANA
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KE2 TECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEY
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KE2 DPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLM
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KE2 ALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYA
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KE2 ALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKS
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KE2 STSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQ
1930 1940 1950 1960 1970 1980
1980 1990 2000 2010 2020 2030
pF1KE2 MQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCS
1990 2000 2010 2020 2030 2040
2040 2050 2060 2070 2080 2090
pF1KE2 TTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPT
2050 2060 2070 2080 2090 2100
2100 2110 2120 2130 2140 2150
pF1KE2 GCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQ
2110 2120 2130 2140 2150 2160
2160 2170 2180 2190 2200 2210
pF1KE2 EPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGA
2170 2180 2190 2200 2210 2220
2220 2230 2240 2250 2260 2270
pF1KE2 QTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPED
2230 2240 2250 2260 2270 2280
2280 2290 2300 2310 2320 2330
pF1KE2 TLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQD
2290 2300 2310 2320 2330 2340
pF1KE2 HWC
:::
XP_016 HWC
>>XP_016870607 (OMIM: 601012,614860) PREDICTED: voltage- (2338 aa)
initn: 10716 init1: 10716 opt: 15702 Z-score: 8108.5 bits: 1514.3 E(87639): 0
Smith-Waterman score: 15702; 100.0% identity (100.0% similar) in 2339 aa overlap (1-2339:1-2338)
10 20 30 40 50 60
pF1KE2 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 YFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNL
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_016 DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAA-QQNSAKARSVWEQRASQLRLQNL
730 740 750 760 770
790 800 810 820 830 840
pF1KE2 RASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAE
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE2 APEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPP
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE2 EARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 GPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNH
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE2 QPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHI
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE2 PVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLR
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE2 RFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVI
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE2 KMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLK
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE2 TIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELER
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE2 DCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYE
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE2 EQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACI
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE2 DFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYE
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE2 LMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETNN
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE2 FINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQV
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KE2 FGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECG
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KE2 SDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE2 CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIR
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE2 TALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMI
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KE2 FDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
1860 1870 1880 1890 1900 1910
1930 1940 1950 1960 1970 1980
pF1KE2 SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSI
1920 1930 1940 1950 1960 1970
1990 2000 2010 2020 2030 2040
pF1KE2 TRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPD
1980 1990 2000 2010 2020 2030
2050 2060 2070 2080 2090 2100
pF1KE2 RPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
2040 2050 2060 2070 2080 2090
2110 2120 2130 2140 2150 2160
pF1KE2 ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGP
2100 2110 2120 2130 2140 2150
2170 2180 2190 2200 2210 2220
pF1KE2 HPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSL
2160 2170 2180 2190 2200 2210
2230 2240 2250 2260 2270 2280
pF1KE2 PAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF
2220 2230 2240 2250 2260 2270
2290 2300 2310 2320 2330
pF1KE2 EEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
2280 2290 2300 2310 2320 2330
>>XP_016870609 (OMIM: 601012,614860) PREDICTED: voltage- (2337 aa)
initn: 15696 init1: 10396 opt: 15696 Z-score: 8105.4 bits: 1513.7 E(87639): 0
Smith-Waterman score: 15696; 99.9% identity (99.9% similar) in 2339 aa overlap (1-2339:1-2337)
10 20 30 40 50 60
pF1KE2 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 YFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 RASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 APEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 EARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 GPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 QPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 PVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 RFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 KMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 TIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELER
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 DCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 EQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACI
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 DFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 LMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETNN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 LMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIA--NN
1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE2 FINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQV
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KE2 FGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECG
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KE2 SDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAA
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE2 CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIR
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE2 TALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMI
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KE2 FDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSL
1860 1870 1880 1890 1900 1910
1930 1940 1950 1960 1970 1980
pF1KE2 SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSI
1920 1930 1940 1950 1960 1970
1990 2000 2010 2020 2030 2040
pF1KE2 TRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPD
1980 1990 2000 2010 2020 2030
2050 2060 2070 2080 2090 2100
pF1KE2 RPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRR
2040 2050 2060 2070 2080 2090
2110 2120 2130 2140 2150 2160
pF1KE2 ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGP
2100 2110 2120 2130 2140 2150
2170 2180 2190 2200 2210 2220
pF1KE2 HPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSL
2160 2170 2180 2190 2200 2210
2230 2240 2250 2260 2270 2280
pF1KE2 PAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTF
2220 2230 2240 2250 2260 2270
2290 2300 2310 2320 2330
pF1KE2 EEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
2280 2290 2300 2310 2320 2330
>>XP_011517293 (OMIM: 601012,614860) PREDICTED: voltage- (2344 aa)
initn: 10253 init1: 7445 opt: 15691 Z-score: 8102.8 bits: 1513.3 E(87639): 0
Smith-Waterman score: 15691; 99.8% identity (99.8% similar) in 2344 aa overlap (1-2339:1-2344)
10 20 30 40 50 60
pF1KE2 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLD-VLKRA
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDAVLKRA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 LRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE2 EAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE2 PEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE2 GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRN
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE2 HQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVH
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE2 IPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLL
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE2 RRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMV
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE2 IKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFS----GSKGKDINTIKSLRVLRV
:::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_011 IKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSSFVGGSKGKDINTIKSLRVLRV
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE2 LRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDES
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE2 KELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSV
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE2 DATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKN
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE2 ERACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDA
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE2 PYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEI
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KE2 AETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAI
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KE2 IGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQAN
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KE2 ATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAE
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KE2 YDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTL
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KE2 MALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVY
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KE2 AALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQK
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KE2 SSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDV
1930 1940 1950 1960 1970 1980
1980 1990 2000 2010 2020 2030
pF1KE2 QMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLC
1990 2000 2010 2020 2030 2040
2040 2050 2060 2070 2080 2090
pF1KE2 STTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGP
2050 2060 2070 2080 2090 2100
2100 2110 2120 2130 2140 2150
pF1KE2 TGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAG
2110 2120 2130 2140 2150 2160
2160 2170 2180 2190 2200 2210
pF1KE2 QEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAG
2170 2180 2190 2200 2210 2220
2220 2230 2240 2250 2260 2270
pF1KE2 AQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPE
2230 2240 2250 2260 2270 2280
2280 2290 2300 2310 2320 2330
pF1KE2 DTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQ
2290 2300 2310 2320 2330 2340
pF1KE2 DHWC
::::
XP_011 DHWC
>>XP_011517296 (OMIM: 601012,614860) PREDICTED: voltage- (2338 aa)
initn: 12883 init1: 7583 opt: 15684 Z-score: 8099.2 bits: 1512.6 E(87639): 0
Smith-Waterman score: 15684; 99.9% identity (99.9% similar) in 2340 aa overlap (1-2339:1-2338)
10 20 30 40 50 60
pF1KE2 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLD-VLKRA
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDAVLKRA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 LRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE2 EAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE2 PEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE2 GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRN
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE2 HQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVH
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE2 IPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLL
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE2 RRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMV
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE2 IKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPL
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE2 KTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELE
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE2 RDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATY
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE2 EEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERAC
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE2 IDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEY
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE2 ELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_011 ELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIA--N
1510 1520 1530 1540 1550
1560 1570 1580 1590 1600 1610
pF1KE2 NFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQ
1560 1570 1580 1590 1600 1610
1620 1630 1640 1650 1660 1670
pF1KE2 VFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATEC
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KE2 GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPA
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KE2 ACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALI
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KE2 RTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900 1910
pF1KE2 IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTS
1860 1870 1880 1890 1900 1910
1920 1930 1940 1950 1960 1970
pF1KE2 LSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQS
1920 1930 1940 1950 1960 1970
1980 1990 2000 2010 2020 2030
pF1KE2 ITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTP
1980 1990 2000 2010 2020 2030
2040 2050 2060 2070 2080 2090
pF1KE2 DRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCR
2040 2050 2060 2070 2080 2090
2100 2110 2120 2130 2140 2150
pF1KE2 RERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPG
2100 2110 2120 2130 2140 2150
2160 2170 2180 2190 2200 2210
pF1KE2 PHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTS
2160 2170 2180 2190 2200 2210
2220 2230 2240 2250 2260 2270
pF1KE2 LPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLT
2220 2230 2240 2250 2260 2270
2280 2290 2300 2310 2320 2330
pF1KE2 FEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
2280 2290 2300 2310 2320 2330
>>XP_011517295 (OMIM: 601012,614860) PREDICTED: voltage- (2341 aa)
initn: 13578 init1: 8278 opt: 15678 Z-score: 8096.1 bits: 1512.0 E(87639): 0
Smith-Waterman score: 15678; 99.7% identity (99.7% similar) in 2343 aa overlap (1-2339:1-2341)
10 20 30 40 50 60
pF1KE2 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 YFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQIL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 RASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 APEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 EARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 GPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNH
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 QPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHI
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 PVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 RFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250
pF1KE2 KMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFS----GSKGKDINTIKSLRVLRVL
::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_011 KMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSSFVGGSKGKDINTIKSLRVLRVL
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE2 RPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESK
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE2 ELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVD
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE2 ATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNE
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE2 RACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAP
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE2 YEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIA
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KE2 ETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --NNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII
1570 1580 1590 1600 1610
1620 1630 1640 1650 1660 1670
pF1KE2 GMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANA
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KE2 TECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEY
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KE2 DPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLM
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KE2 ALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYA
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900 1910
pF1KE2 ALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKS
1860 1870 1880 1890 1900 1910
1920 1930 1940 1950 1960 1970
pF1KE2 STSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQ
1920 1930 1940 1950 1960 1970
1980 1990 2000 2010 2020 2030
pF1KE2 MQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCS
1980 1990 2000 2010 2020 2030
2040 2050 2060 2070 2080 2090
pF1KE2 TTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPT
2040 2050 2060 2070 2080 2090
2100 2110 2120 2130 2140 2150
pF1KE2 GCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQ
2100 2110 2120 2130 2140 2150
2160 2170 2180 2190 2200 2210
pF1KE2 EPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGA
2160 2170 2180 2190 2200 2210
2220 2230 2240 2250 2260 2270
pF1KE2 QTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPED
2220 2230 2240 2250 2260 2270
2280 2290 2300 2310 2320 2330
pF1KE2 TLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQD
2280 2290 2300 2310 2320 2330
pF1KE2 HWC
:::
XP_011 HWC
2340
>>XP_011517294 (OMIM: 601012,614860) PREDICTED: voltage- (2343 aa)
initn: 7445 init1: 7445 opt: 15672 Z-score: 8093.0 bits: 1511.4 E(87639): 0
Smith-Waterman score: 15672; 99.7% identity (99.7% similar) in 2344 aa overlap (1-2339:1-2343)
10 20 30 40 50 60
pF1KE2 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLD-VLKRA
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDAVLKRA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_011 KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAA-QQNSAKARSVWEQRASQLRLQN
730 740 750 760 770
780 790 800 810 820 830
pF1KE2 LRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
780 790 800 810 820 830
840 850 860 870 880 890
pF1KE2 EAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGP
840 850 860 870 880 890
900 910 920 930 940 950
pF1KE2 PEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KE2 GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRN
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KE2 HQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVH
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KE2 IPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLL
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
pF1KE2 RRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMV
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
pF1KE2 IKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFS----GSKGKDINTIKSLRVLRV
:::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_011 IKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSSFVGGSKGKDINTIKSLRVLRV
1200 1210 1220 1230 1240 1250
1260 1270 1280 1290 1300 1310
pF1KE2 LRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDES
1260 1270 1280 1290 1300 1310
1320 1330 1340 1350 1360 1370
pF1KE2 KELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSV
1320 1330 1340 1350 1360 1370
1380 1390 1400 1410 1420 1430
pF1KE2 DATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKN
1380 1390 1400 1410 1420 1430
1440 1450 1460 1470 1480 1490
pF1KE2 ERACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDA
1440 1450 1460 1470 1480 1490
1500 1510 1520 1530 1540 1550
pF1KE2 PYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEI
1500 1510 1520 1530 1540 1550
1560 1570 1580 1590 1600 1610
pF1KE2 AETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAI
1560 1570 1580 1590 1600 1610
1620 1630 1640 1650 1660 1670
pF1KE2 IGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQAN
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KE2 ATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAE
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KE2 YDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTL
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KE2 MALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVY
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900 1910
pF1KE2 AALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQK
1860 1870 1880 1890 1900 1910
1920 1930 1940 1950 1960 1970
pF1KE2 SSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDV
1920 1930 1940 1950 1960 1970
1980 1990 2000 2010 2020 2030
pF1KE2 QMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLC
1980 1990 2000 2010 2020 2030
2040 2050 2060 2070 2080 2090
pF1KE2 STTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGP
2040 2050 2060 2070 2080 2090
2100 2110 2120 2130 2140 2150
pF1KE2 TGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAG
2100 2110 2120 2130 2140 2150
2160 2170 2180 2190 2200 2210
pF1KE2 QEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAG
2160 2170 2180 2190 2200 2210
2220 2230 2240 2250 2260 2270
pF1KE2 AQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPE
2220 2230 2240 2250 2260 2270
2280 2290 2300 2310 2320 2330
pF1KE2 DTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQ
2280 2290 2300 2310 2320 2330
pF1KE2 DHWC
::::
XP_011 DHWC
2340
>>XP_016870605 (OMIM: 601012,614860) PREDICTED: voltage- (2342 aa)
initn: 10765 init1: 5465 opt: 15666 Z-score: 8089.9 bits: 1510.9 E(87639): 0
Smith-Waterman score: 15666; 99.7% identity (99.7% similar) in 2344 aa overlap (1-2339:1-2342)
10 20 30 40 50 60
pF1KE2 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLD-VLKRA
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDAVLKRA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPR
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 LRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE2 EAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGP
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE2 PEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE2 GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRN
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE2 HQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVH
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE2 IPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLL
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KE2 RRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMV
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KE2 IKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFS----GSKGKDINTIKSLRVLRV
:::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_016 IKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSSFVGGSKGKDINTIKSLRVLRV
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KE2 LRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDES
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KE2 KELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSV
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KE2 DATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKN
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KE2 ERACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDA
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KE2 PYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEI
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KE2 AETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAI
: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 A--NNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAI
1570 1580 1590 1600 1610
1620 1630 1640 1650 1660 1670
pF1KE2 IGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQAN
1620 1630 1640 1650 1660 1670
1680 1690 1700 1710 1720 1730
pF1KE2 ATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAE
1680 1690 1700 1710 1720 1730
1740 1750 1760 1770 1780 1790
pF1KE2 YDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTL
1740 1750 1760 1770 1780 1790
1800 1810 1820 1830 1840 1850
pF1KE2 MALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVY
1800 1810 1820 1830 1840 1850
1860 1870 1880 1890 1900 1910
pF1KE2 AALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQK
1860 1870 1880 1890 1900 1910
1920 1930 1940 1950 1960 1970
pF1KE2 SSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDV
1920 1930 1940 1950 1960 1970
1980 1990 2000 2010 2020 2030
pF1KE2 QMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLC
1980 1990 2000 2010 2020 2030
2040 2050 2060 2070 2080 2090
pF1KE2 STTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGP
2040 2050 2060 2070 2080 2090
2100 2110 2120 2130 2140 2150
pF1KE2 TGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAG
2100 2110 2120 2130 2140 2150
2160 2170 2180 2190 2200 2210
pF1KE2 QEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAG
2160 2170 2180 2190 2200 2210
2220 2230 2240 2250 2260 2270
pF1KE2 AQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPE
2220 2230 2240 2250 2260 2270
2280 2290 2300 2310 2320 2330
pF1KE2 DTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQ
2280 2290 2300 2310 2320 2330
pF1KE2 DHWC
::::
XP_016 DHWC
2340
2339 residues in 1 query sequences
62246620 residues in 87639 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Jul 6 13:34:10 2017 done: Thu Jul 6 13:34:14 2017
Total Scan time: 23.660 Total Display time: 1.800
Function used was FASTA [36.3.4 Apr, 2011]