Result of FASTA (omim) for
pF1KE2680
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2680, 427 aa
1>>>pF1KE2680 427 - 427 aa - 427 aa
Library: /omim/omim.rfq.tfa
61573307 residues in 86401 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1931+/-0.000333; mu= 19.0885+/- 0.021
mean_var=68.6748+/-13.376, 0's: 0 Z-trim(114.5): 159 B-trim: 21 in 1/56
Lambda= 0.154766
statistics sampled from 24434 (24607) to 24434 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.285), width: 16
Scan time: 6.600
The best scores are: opt bits E(86401)
NP_004631 (OMIM: 142560) spliceosome RNA helicase ( 428) 2594 588.0 1.5e-167
NP_542165 (OMIM: 142560) spliceosome RNA helicase ( 428) 2594 588.0 1.5e-167
NP_001958 (OMIM: 601102) eukaryotic initiation fac ( 407) 891 207.8 4.3e-53
NP_001407 (OMIM: 602641) eukaryotic initiation fac ( 406) 874 204.0 6e-52
NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411) 858 200.4 7.2e-51
NP_004388 (OMIM: 600326) probable ATP-dependent RN ( 483) 838 196.0 1.8e-49
NP_001244120 (OMIM: 600326) probable ATP-dependent ( 483) 838 196.0 1.8e-49
XP_005271474 (OMIM: 600326) PREDICTED: probable AT ( 483) 838 196.0 1.8e-49
NP_009135 (OMIM: 606168) probable ATP-dependent RN ( 824) 776 182.3 4.1e-45
NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 735 173.0 1.4e-42
NP_009173 (OMIM: 605812) ATP-dependent RNA helicas ( 479) 716 168.7 2.8e-41
XP_011521136 (OMIM: 605812) PREDICTED: ATP-depende ( 484) 716 168.7 2.9e-41
XP_011521134 (OMIM: 605812) PREDICTED: ATP-depende ( 539) 716 168.8 3.1e-41
NP_060365 (OMIM: 616621) probable ATP-dependent RN ( 796) 686 162.2 4.4e-39
NP_001244103 (OMIM: 605812) ATP-dependent RNA heli ( 370) 668 157.9 3.9e-38
XP_016878379 (OMIM: 605812) PREDICTED: ATP-depende ( 370) 668 157.9 3.9e-38
XP_006721190 (OMIM: 605812) PREDICTED: ATP-depende ( 370) 668 157.9 3.9e-38
NP_001014449 (OMIM: 605812) ATP-dependent RNA heli ( 370) 668 157.9 3.9e-38
NP_001244102 (OMIM: 605812) ATP-dependent RNA heli ( 370) 668 157.9 3.9e-38
NP_001191439 (OMIM: 602641) eukaryotic initiation ( 347) 655 155.0 2.8e-37
XP_011523824 (OMIM: 268305,608546) PREDICTED: euka ( 390) 651 154.2 5.6e-37
XP_011541093 (OMIM: 607663) PREDICTED: ATP-depende ( 482) 641 152.0 3.1e-36
NP_037396 (OMIM: 607663) ATP-dependent RNA helicas ( 483) 641 152.0 3.1e-36
XP_011541092 (OMIM: 607663) PREDICTED: ATP-depende ( 486) 641 152.0 3.2e-36
NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 641 152.1 3.8e-36
XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619) 641 152.1 3.8e-36
XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 641 152.1 3.8e-36
XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 641 152.1 3.8e-36
NP_001014451 (OMIM: 605812) ATP-dependent RNA heli ( 448) 636 150.9 6.4e-36
NP_001244101 (OMIM: 605812) ATP-dependent RNA heli ( 453) 636 150.9 6.5e-36
XP_011521135 (OMIM: 605812) PREDICTED: ATP-depende ( 508) 636 150.9 7.1e-36
NP_001317367 (OMIM: 607663) ATP-dependent RNA heli ( 369) 597 142.1 2.3e-33
XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439) 589 140.4 9.1e-33
XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529) 589 140.4 1.1e-32
XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529) 589 140.4 1.1e-32
XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604) 589 140.4 1.2e-32
NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648) 589 140.5 1.2e-32
XP_016879601 (OMIM: 613369) PREDICTED: ATP-depende ( 775) 579 138.3 6.7e-32
XP_006721720 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 579 138.3 7.9e-32
NP_031398 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 579 138.3 7.9e-32
XP_016879600 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 579 138.3 7.9e-32
NP_987095 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 579 138.3 7.9e-32
XP_011540947 (OMIM: 600326) PREDICTED: probable AT ( 434) 571 136.3 1.5e-31
NP_001244104 (OMIM: 605812) ATP-dependent RNA heli ( 328) 561 134.0 5.5e-31
NP_006377 (OMIM: 608469) probable ATP-dependent RN ( 729) 565 135.1 5.6e-31
NP_001091974 (OMIM: 608469) probable ATP-dependent ( 731) 565 135.1 5.6e-31
NP_006764 (OMIM: 606355) ATP-dependent RNA helicas ( 670) 563 134.7 7.1e-31
NP_001307525 (OMIM: 180630) probable ATP-dependent ( 614) 554 132.6 2.7e-30
NP_001307526 (OMIM: 180630) probable ATP-dependent ( 614) 554 132.6 2.7e-30
NP_004387 (OMIM: 180630) probable ATP-dependent RN ( 614) 554 132.6 2.7e-30
>>NP_004631 (OMIM: 142560) spliceosome RNA helicase DDX3 (428 aa)
initn: 2585 init1: 2519 opt: 2594 Z-score: 3129.0 bits: 588.0 E(86401): 1.5e-167
Smith-Waterman score: 2594; 90.0% identity (97.7% similar) in 428 aa overlap (1-427:1-428)
10 20 30 40 50
pF1KE2 MAEQDVENDLLDY-DEEEEPQAPQESTPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAI
:::.::.:.:::: :.: : : ... :: :::.:::::::::::::::::::::::::
NP_004 MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMC
::::::::::::::::::::::::::::::::::::::::::::::.:::.:::.:::::
NP_004 VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 HTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRILALV
:::::::::::::::::::::.:::.:::::::::::::::::::::.:::::::::::.
NP_004 HTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 RNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCR
::.:..::..:::.::::::::::::::::::::::.:::::: :::::::::.::::::
NP_004 RNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 KFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVIIFVKSVQRC
::::::::.::::::::::::::::::::::.::::::::::::::::::.:::::::::
NP_004 KFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRC
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 MALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVF
.:::::::::::::::::::: ::::::::::::::::::::::::::::::::::::.:
NP_004 IALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAF
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 NYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAELPEEIDI
::::::::::::::::::::::::::::::::::::::::::::::::::..:::.::::
NP_004 NYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDI
370 380 390 400 410 420
420
pF1KE2 STYIEQSR
:.::::.:
NP_004 SSYIEQTR
>>NP_542165 (OMIM: 142560) spliceosome RNA helicase DDX3 (428 aa)
initn: 2585 init1: 2519 opt: 2594 Z-score: 3129.0 bits: 588.0 E(86401): 1.5e-167
Smith-Waterman score: 2594; 90.0% identity (97.7% similar) in 428 aa overlap (1-427:1-428)
10 20 30 40 50
pF1KE2 MAEQDVENDLLDY-DEEEEPQAPQESTPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAI
:::.::.:.:::: :.: : : ... :: :::.:::::::::::::::::::::::::
NP_542 MAENDVDNELLDYEDDEVETAAGGDGAEAPAKKDVKGSYVSIHSSGFRDFLLKPELLRAI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMC
::::::::::::::::::::::::::::::::::::::::::::::.:::.:::.:::::
NP_542 VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVTGQVSVLVMC
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 HTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRILALV
:::::::::::::::::::::.:::.:::::::::::::::::::::.:::::::::::.
NP_542 HTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 RNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCR
::.:..::..:::.::::::::::::::::::::::.:::::: :::::::::.::::::
NP_542 RNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 KFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVIIFVKSVQRC
::::::::.::::::::::::::::::::::.::::::::::::::::::.:::::::::
NP_542 KFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFVKSVQRC
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 MALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVF
.:::::::::::::::::::: ::::::::::::::::::::::::::::::::::::.:
NP_542 IALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIAF
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 NYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAELPEEIDI
::::::::::::::::::::::::::::::::::::::::::::::::::..:::.::::
NP_542 NYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNISELPDEIDI
370 380 390 400 410 420
420
pF1KE2 STYIEQSR
:.::::.:
NP_542 SSYIEQTR
>>NP_001958 (OMIM: 601102) eukaryotic initiation factor (407 aa)
initn: 797 init1: 411 opt: 891 Z-score: 1074.3 bits: 207.8 E(86401): 4.3e-53
Smith-Waterman score: 891; 38.3% identity (72.4% similar) in 373 aa overlap (46-417:35-403)
20 30 40 50 60 70
pF1KE2 EEEPQAPQESTPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECI
: :. :: :::.: :::.:: .:.. :
NP_001 SADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAI
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE2 PQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCHTRELAFQISKEYERF
: :.::. ::.:: ::::.:... :::.: .. .::. ::::: ::.: .
NP_001 IPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILAL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 SKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRILALVRNRSFSLKNVKHFVLD
. :: .. . .:: ..... . :. . ::.:::::::.. .. : .: : .: ::::
NP_001 GDYM-GATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLD
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 ECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETK
: :.:: . .. .. :::. : ...:::. :. : .:::.::....: : .
NP_001 EADEMLSR-GFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE-E
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE2 LTLHGLQQYYVKLKDSE-KNRKLFDLLDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAI
:::.:..:.:.... : : : :: ..: ..:..::... .. :.. . ..: .
NP_001 LTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVS
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE2 AIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRV
:.: : :.:: ...:.. . :.:..:.:..::.:...:..:.:::.: . ..:.::.
NP_001 ALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI
310 320 330 340 350 360
380 390 400 410 420
pF1KE2 ARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAELPEEIDISTYIEQSR
.:.:::: ::.::.::..: : .:: :.. ....: :.: ..
NP_001 GRGGRFGRKGVAINFVTEE-DKRILRDIETFYNTTVEEMPMNVADLI
370 380 390 400
>>NP_001407 (OMIM: 602641) eukaryotic initiation factor (406 aa)
initn: 781 init1: 405 opt: 874 Z-score: 1053.8 bits: 204.0 E(86401): 6e-52
Smith-Waterman score: 874; 36.5% identity (72.0% similar) in 389 aa overlap (30-417:19-402)
10 20 30 40 50 60
pF1KE2 MAEQDVENDLLDYDEEEEPQAPQESTPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAIV
:. :.... : .: : :. :. :::.:
NP_001 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDS-FDDMNLSESLLRGIY
10 20 30 40
70 80 90 100 110 120
pF1KE2 DCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCH
:::.:: .:.. : : :.::. ::.:: ::::.:... ::::: . .::.
NP_001 AYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 TRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRILALVR
::::: ::.: .. :: ... . .:: ... . . :. . ::..::::::.. ..
NP_001 TRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLN
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 NRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCRK
: .: : .: ::::: :.:: . .. .. .::. . : ...:::. .:. : .:
NP_001 RRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKK
170 180 190 200 210 220
250 260 270 280 290
pF1KE2 FMQDPMEVFVDDETKLTLHGLQQYYVKLKDSE-KNRKLFDLLDVLEFNQVIIFVKSVQRC
::.::....: : .:::.:..:.:.... : : : :: ..: ..:..::... ..
NP_001 FMRDPIRILVKKE-ELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKV
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 MALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVF
:.. . ..: . :.: : :.:: ...:.. . :.:..:.:..::.:...:..:.
NP_001 DWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVI
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE2 NYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAELPEEIDI
:::.: . ..:.::..:.:::: ::.::..:..: : . : :.. ..... :.: ..
NP_001 NYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE-DKRTLRDIETFYNTSIEEMPLNVAD
350 360 370 380 390 400
420
pF1KE2 STYIEQSR
NP_001 LI
>>NP_055555 (OMIM: 268305,608546) eukaryotic initiation (411 aa)
initn: 715 init1: 379 opt: 858 Z-score: 1034.4 bits: 200.4 E(86401): 7.2e-51
Smith-Waterman score: 858; 35.9% identity (71.6% similar) in 373 aa overlap (46-417:40-407)
20 30 40 50 60 70
pF1KE2 EEEPQAPQESTPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECI
: . :. .:::.: :::.:: .:.. :
NP_055 SGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAI
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE2 PQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCHTRELAFQISKEYERF
: : : ::. :..:: ::::.: ...:: .. .. .:.. ::::: ::.: .
NP_055 KQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLAL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 SKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRILALVRNRSFSLKNVKHFVLD
. :: .:. . .:: .. .: . : . :::.:::::.. ..: ::. . .: .:::
NP_055 GDYM-NVQCHACIGGTNVGEDIRKLDYG-QHVVAGTPGRVFDMIRRRSLRTRAIKMLVLD
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 ECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETK
: :.::.. ..... ...: : : ...:::: ..: . ::: ::....: . .
NP_055 EADEMLNK-GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRD-E
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE2 LTLHGLQQYYVKLKDSE-KNRKLFDLLDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAI
:::.:..:..: .. : : : :: :.: ..:..:: .. .. :.. . : :: .
NP_055 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVS
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE2 AIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRV
..: : :.:: : ...:.. :.:..:....::.:. .:....:::.:.. . :.::.
NP_055 SMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI
310 320 330 340 350 360
380 390 400 410 420
pF1KE2 ARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAELPEEIDISTYIEQSR
.:.::.: ::.::.::... : .:: :... . ... :.: ..
NP_055 GRSGRYGRKGVAINFVKND-DIRILRDIEQYYSTQIDEMPMNVADLI
370 380 390 400 410
>>NP_004388 (OMIM: 600326) probable ATP-dependent RNA he (483 aa)
initn: 725 init1: 358 opt: 838 Z-score: 1009.3 bits: 196.0 E(86401): 1.8e-49
Smith-Waterman score: 838; 35.7% identity (69.7% similar) in 406 aa overlap (23-425:73-472)
10 20 30 40 50
pF1KE2 MAEQDVENDLLDYDEEEEPQAPQESTPAPPKK-DIKGSYV-SIHSSGFRDFL
... ::: :: : : : ... :.:.
NP_004 NQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYC
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE2 LKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVN
:: ::: .: . :.:.:: .:.: :: :. : :.: .::.: ::...... :.... .
NP_004 LKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKK
110 120 130 140 150 160
120 130 140 150 160
pF1KE2 GQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLK-KNCPHVVV
.. ..:. :::::.:.:. . ::.: ..:: . :: ... : ... . :::.
NP_004 DNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDD--IMRLDDTVHVVI
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE2 GTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSAT
.:::::: :... .. .:. .:::: ::.: : :. . ...:. :...: ...:::
NP_004 ATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMEDIILTLPKNRQILLYSAT
230 240 250 260 270
230 240 250 260 270 280
pF1KE2 LSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQV
. ... . .: :.:. . .: :::.:. :::. . . .: . : :.. :..::
NP_004 FPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQS
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE2 IIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRG
::: .: :: ::. . . .. . :: : ::.: ...:.. : :: :.:: ::
NP_004 IIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRG
340 350 360 370 380 390
350 360 370 380 390 400
pF1KE2 MDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVN
.::. ::.:.:.:.:. ..:::::..:.:::: ::::.... .: :....... ..
NP_004 IDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLIT-YDDRFNLKSIEEQLGTE
400 410 420 430 440 450
410 420
pF1KE2 VAELPEEIDISTYIEQSR
. .: .:: : :. .
NP_004 IKPIPSNIDKSLYVAEYHSEPVEDEKP
460 470 480
>>NP_001244120 (OMIM: 600326) probable ATP-dependent RNA (483 aa)
initn: 725 init1: 358 opt: 838 Z-score: 1009.3 bits: 196.0 E(86401): 1.8e-49
Smith-Waterman score: 838; 35.7% identity (69.7% similar) in 406 aa overlap (23-425:73-472)
10 20 30 40 50
pF1KE2 MAEQDVENDLLDYDEEEEPQAPQESTPAPPKK-DIKGSYV-SIHSSGFRDFL
... ::: :: : : : ... :.:.
NP_001 NQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYC
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE2 LKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVN
:: ::: .: . :.:.:: .:.: :: :. : :.: .::.: ::...... :.... .
NP_001 LKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKK
110 120 130 140 150 160
120 130 140 150 160
pF1KE2 GQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLK-KNCPHVVV
.. ..:. :::::.:.:. . ::.: ..:: . :: ... : ... . :::.
NP_001 DNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDD--IMRLDDTVHVVI
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE2 GTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSAT
.:::::: :... .. .:. .:::: ::.: : :. . ...:. :...: ...:::
NP_001 ATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMEDIILTLPKNRQILLYSAT
230 240 250 260 270
230 240 250 260 270 280
pF1KE2 LSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQV
. ... . .: :.:. . .: :::.:. :::. . . .: . : :.. :..::
NP_001 FPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQS
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE2 IIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRG
::: .: :: ::. . . .. . :: : ::.: ...:.. : :: :.:: ::
NP_001 IIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRG
340 350 360 370 380 390
350 360 370 380 390 400
pF1KE2 MDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVN
.::. ::.:.:.:.:. ..:::::..:.:::: ::::.... .: :....... ..
NP_001 IDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLIT-YDDRFNLKSIEEQLGTE
400 410 420 430 440 450
410 420
pF1KE2 VAELPEEIDISTYIEQSR
. .: .:: : :. .
NP_001 IKPIPSNIDKSLYVAEYHSEPVEDEKP
460 470 480
>>XP_005271474 (OMIM: 600326) PREDICTED: probable ATP-de (483 aa)
initn: 725 init1: 358 opt: 838 Z-score: 1009.3 bits: 196.0 E(86401): 1.8e-49
Smith-Waterman score: 838; 35.7% identity (69.7% similar) in 406 aa overlap (23-425:73-472)
10 20 30 40 50
pF1KE2 MAEQDVENDLLDYDEEEEPQAPQESTPAPPKK-DIKGSYV-SIHSSGFRDFL
... ::: :: : : : ... :.:.
XP_005 NQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYC
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE2 LKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVN
:: ::: .: . :.:.:: .:.: :: :. : :.: .::.: ::...... :.... .
XP_005 LKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKK
110 120 130 140 150 160
120 130 140 150 160
pF1KE2 GQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLK-KNCPHVVV
.. ..:. :::::.:.:. . ::.: ..:: . :: ... : ... . :::.
XP_005 DNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDD--IMRLDDTVHVVI
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE2 GTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSAT
.:::::: :... .. .:. .:::: ::.: : :. . ...:. :...: ...:::
XP_005 ATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQ-DFVQIMEDIILTLPKNRQILLYSAT
230 240 250 260 270
230 240 250 260 270 280
pF1KE2 LSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQV
. ... . .: :.:. . .: :::.:. :::. . . .: . : :.. :..::
XP_005 FPLSVQKFMNSHLQKPYEINLMEE--LTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQS
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE2 IIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRG
::: .: :: ::. . . .. . :: : ::.: ...:.. : :: :.:: ::
XP_005 IIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRG
340 350 360 370 380 390
350 360 370 380 390 400
pF1KE2 MDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVN
.::. ::.:.:.:.:. ..:::::..:.:::: ::::.... .: :....... ..
XP_005 IDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLIT-YDDRFNLKSIEEQLGTE
400 410 420 430 440 450
410 420
pF1KE2 VAELPEEIDISTYIEQSR
. .: .:: : :. .
XP_005 IKPIPSNIDKSLYVAEYHSEPVEDEKP
460 470 480
>>NP_009135 (OMIM: 606168) probable ATP-dependent RNA he (824 aa)
initn: 775 init1: 370 opt: 776 Z-score: 931.1 bits: 182.3 E(86401): 4.1e-45
Smith-Waterman score: 783; 34.1% identity (65.9% similar) in 419 aa overlap (20-417:26-440)
10 20 30 40
pF1KE2 MAEQDVENDLLDYDEEEEPQAPQ-ESTPAPPK-----KDIK------GSYVSIH
:.: : ::.: . .:.. :. . .
NP_009 MAAAFEASGALAAVATAMPAEHVAVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 SSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLAT
. :...::. .:... :::.:: :: . :: . :.:.. ::::: ::: :: .
NP_009 PADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 LQQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKK
:... : .. .:.. :::.: :: . .. : ... ::.:: ...:. :::
NP_009 LDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 NCPHVVVGTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQ
: :..::.:::: :.. .. ... :.::: ::.::. ....... :. : ::
NP_009 -C-HIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQ
190 200 210 220 230
230 240 250 260 270
pF1KE2 CMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDS---------EK
. ::: . . . :.:.:: : ... . .: ::.::: :. .: ::
NP_009 MLAVSATYPEFLANALTKYMRDPTFVRLNS-SDPSLIGLKQYY-KVVNSYPLAHKVFEEK
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE2 NRKLFDLLDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFK
...: .:.. . :::...: . .: . ::..: ..::: : .: :..::. . ..:
NP_009 TQHLQELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLK
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE2 DFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDE
:. :.:..:.: .::.: :.::.: : :.: : .::.::..::::::: ::..:.
NP_009 HFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRG
360 370 380 390 400 410
400 410 420
pF1KE2 NDAKILNDVQDRFEVNVAELPEEIDISTYIEQSR
.. ... . .. ..:. ::. :
NP_009 EEENMMMRIAQKCNINLLPLPDPIPSGLMEECVDWDVEVKAAVHTYGIASVPNQPLKKQI
420 430 440 450 460 470
>>NP_057439 (OMIM: 615428) probable ATP-dependent RNA he (455 aa)
initn: 649 init1: 315 opt: 735 Z-score: 885.3 bits: 173.0 E(86401): 1.4e-42
Smith-Waterman score: 735; 32.3% identity (68.6% similar) in 405 aa overlap (17-418:5-394)
10 20 30 40 50
pF1KE2 MAEQDVENDLLDYDEEEEPQAPQE-STPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAI
:: ..: : : : ... : :.:. . : .:
NP_057 MAAPEEHDSPTEASQPIVEEEETKT---------FKDLGVTDVLCEAC
10 20 30
60 70 80 90 100 110
pF1KE2 VDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMC
. :. .:...: : :: :. : :.. :..: :::..:.: :. . . .. .::.
NP_057 DQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLT
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE2 HTRELAFQISKEYERFSKYMPSVKVSVFFGGL-SIKKDEEVLKKNCPHVVVGTPGRILAL
:::::::::...: ... . .:. .:. ::. :.... . :: ::....::::..
NP_057 PTRELAFQISEQFEALGSSI-GVQSAVIVGGIDSMSQSLALAKK--PHIIIATPGRLIDH
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE2 VRN-RSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPV
..: ..:.:. .:..:.:: :..:. .:.. .:..:... :.... ..::::..: .. .
NP_057 LENTKGFNLRALKYLVMDEADRILN-MDFETEVDKILKVIPRDRKTFLFSATMTKKVQKL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE2 CRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVIIFVKSVQ
: ...:.. :... . :.. :::::. . .. :. : .:. : :. .:: .. .
NP_057 QRAALKNPVKCAVSSKYQ-TVEKLQQYYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCN
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE2 RCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNI
. : :: . .: :: .: :.: .::. ..:: : ::.::.. .::.:: .:..
NP_057 NTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE2 VFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAELPEEI
: :.:.: : :.:::.:..: : .: :::::. . :..... .. . .. .: .
NP_057 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVT-QYDVELFQRIEHLIGKKLPGFPTQD
340 350 360 370 380 390
420
pF1KE2 DISTYIEQSR
:
NP_057 DEVMMLTERVAEAQRFARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRK
400 410 420 430 440 450
427 residues in 1 query sequences
61573307 residues in 86401 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Mar 1 16:48:51 2017 done: Wed Mar 1 16:48:53 2017
Total Scan time: 6.600 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]