Result of FASTA (omim) for
pF1KE2662
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2662, 247 aa
1>>>pF1KE2662 247 - 247 aa - 247 aa
Library: /omim/omim.rfq.tfa
61127809 residues in 85815 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.3788+/-0.000356; mu= 19.5245+/- 0.022
mean_var=59.6448+/-12.611, 0's: 0 Z-trim(114.5): 31 B-trim: 1026 in 1/49
Lambda= 0.166069
statistics sampled from 24462 (24492) to 24462 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.285), width: 16
Scan time: 5.140
The best scores are: opt bits E(85815)
XP_016861848 (OMIM: 610240) PREDICTED: lipoma HMGI ( 247) 1704 416.3 2.5e-116
NP_940962 (OMIM: 610240) lipoma HMGIC fusion partn ( 247) 1704 416.3 2.5e-116
XP_005250384 (OMIM: 609719) PREDICTED: lipoma HMGI ( 232) 1217 299.6 3.1e-81
NP_945351 (OMIM: 609719) lipoma HMGIC fusion partn ( 236) 1209 297.7 1.2e-80
NP_872354 (OMIM: 609427,610265) tetraspan membrane ( 219) 994 246.2 3.6e-65
XP_016861849 (OMIM: 610240) PREDICTED: lipoma HMGI ( 138) 929 230.4 1.3e-60
NP_005771 (OMIM: 606710) lipoma HMGIC fusion partn ( 200) 331 87.3 2.2e-17
XP_011533163 (OMIM: 606710) PREDICTED: lipoma HMGI ( 200) 331 87.3 2.2e-17
XP_006714578 (OMIM: 609718) PREDICTED: lipoma HMGI ( 228) 282 75.6 8.4e-14
NP_005770 (OMIM: 609718) lipoma HMGIC fusion partn ( 228) 282 75.6 8.4e-14
XP_011529246 (OMIM: 300566) PREDICTED: lipoma HMGI ( 220) 280 75.1 1.1e-13
NP_835469 (OMIM: 300566) lipoma HMGIC fusion partn ( 220) 280 75.1 1.1e-13
XP_011529245 (OMIM: 300566) PREDICTED: lipoma HMGI ( 243) 280 75.2 1.2e-13
XP_016884974 (OMIM: 300566) PREDICTED: lipoma HMGI ( 243) 280 75.2 1.2e-13
XP_011529248 (OMIM: 300566) PREDICTED: lipoma HMGI ( 187) 137 40.8 0.0021
>>XP_016861848 (OMIM: 610240) PREDICTED: lipoma HMGIC fu (247 aa)
initn: 1704 init1: 1704 opt: 1704 Z-score: 2209.7 bits: 416.3 E(85815): 2.5e-116
Smith-Waterman score: 1704; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247)
10 20 30 40 50 60
pF1KE2 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFSLFFFCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFSLFFFCN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 IIGILNALILSFLAFVLGNRQTDLLQEELKPENKDFVGSTVSSVLRPGGDVSGWGVLPCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIGILNALILSFLAFVLGNRQTDLLQEELKPENKDFVGSTVSSVLRPGGDVSGWGVLPCP
190 200 210 220 230 240
pF1KE2 VAHSQGP
:::::::
XP_016 VAHSQGP
>>NP_940962 (OMIM: 610240) lipoma HMGIC fusion partner-l (247 aa)
initn: 1704 init1: 1704 opt: 1704 Z-score: 2209.7 bits: 416.3 E(85815): 2.5e-116
Smith-Waterman score: 1704; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247)
10 20 30 40 50 60
pF1KE2 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFSLFFFCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 LFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFSLFFFCN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 TATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 IIGILNALILSFLAFVLGNRQTDLLQEELKPENKDFVGSTVSSVLRPGGDVSGWGVLPCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 IIGILNALILSFLAFVLGNRQTDLLQEELKPENKDFVGSTVSSVLRPGGDVSGWGVLPCP
190 200 210 220 230 240
pF1KE2 VAHSQGP
:::::::
NP_940 VAHSQGP
>>XP_005250384 (OMIM: 609719) PREDICTED: lipoma HMGIC fu (232 aa)
initn: 1215 init1: 808 opt: 1217 Z-score: 1579.4 bits: 299.6 E(85815): 3.1e-81
Smith-Waterman score: 1217; 78.6% identity (92.6% similar) in 215 aa overlap (1-215:15-228)
10 20 30 40
pF1KE2 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYW
:::.:::.:::: .:.:::::::::::::::::::.::: ::::::
XP_005 MPGAAAAAAAAAAAMLPAQEAAKLYHTNYVRNSRAIGVLWAIFTICFAIVNVVCFIQPYW
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 VGDSVSTPKPGYFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLI
.::.:.::. :::::::::.:.:.. ::::::::::::::.::.:::::.::. :::.::
XP_005 IGDGVDTPQAGYFGLFHYCIGNGFS-RELTCRGSFTDFSTLPSGAFKAASFFIGLSMMLI
70 80 90 100 110
110 120 130 140 150 160
pF1KE2 LGCITCFSLFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKY
..:: ::.::::::::::::::::::: .: ::::::::::::::.. .. ::: :: ::
XP_005 IACIICFTLFFFCNTATVYKICAWMQLTSAACLVLGCMIFPDGWDSDEVKRMCGEKTDKY
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 SLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQTDLLQEELKPENKDFVGSTVSSVLR
.:: :::::::::::::::.::::::::::::::: .:. :::: ::::
XP_005 TLGACSVRWAYILAIIGILDALILSFLAFVLGNRQDSLMAEELKAENKDDGNA
180 190 200 210 220 230
230 240
pF1KE2 PGGDVSGWGVLPCPVAHSQGP
>>NP_945351 (OMIM: 609719) lipoma HMGIC fusion partner-l (236 aa)
initn: 1207 init1: 800 opt: 1209 Z-score: 1569.0 bits: 297.7 E(85815): 1.2e-80
Smith-Waterman score: 1209; 78.5% identity (92.5% similar) in 214 aa overlap (1-214:15-227)
10 20 30 40
pF1KE2 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYW
:::.:::.:::: .:.:::::::::::::::::::.::: ::::::
NP_945 MPGAAAAAAAAAAAMLPAQEAAKLYHTNYVRNSRAIGVLWAIFTICFAIVNVVCFIQPYW
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 VGDSVSTPKPGYFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLI
.::.:.::. :::::::::.:.:.. ::::::::::::::.::.:::::.::. :::.::
NP_945 IGDGVDTPQAGYFGLFHYCIGNGFS-RELTCRGSFTDFSTLPSGAFKAASFFIGLSMMLI
70 80 90 100 110
110 120 130 140 150 160
pF1KE2 LGCITCFSLFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKY
..:: ::.::::::::::::::::::: .: ::::::::::::::.. .. ::: :: ::
NP_945 IACIICFTLFFFCNTATVYKICAWMQLTSAACLVLGCMIFPDGWDSDEVKRMCGEKTDKY
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 SLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQTDLLQEELKPENKDFVGSTVSSVLR
.:: :::::::::::::::.::::::::::::::: .:. :::: :::
NP_945 TLGACSVRWAYILAIIGILDALILSFLAFVLGNRQDSLMAEELKAENKVLLSQYSLE
180 190 200 210 220 230
230 240
pF1KE2 PGGDVSGWGVLPCPVAHSQGP
>>NP_872354 (OMIM: 609427,610265) tetraspan membrane pro (219 aa)
initn: 989 init1: 649 opt: 994 Z-score: 1291.0 bits: 246.2 E(85815): 3.6e-65
Smith-Waterman score: 994; 61.8% identity (84.8% similar) in 217 aa overlap (1-217:4-219)
10 20 30 40 50
pF1KE2 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPG
.::.:::.:.:: .:.:::::.::.:. .::::... ...::::::.::::.::. :
NP_872 MVKLLPAQEAAKIYHTNYVRNSRAVGVMWGTLTICFSVLVMALFIQPYWIGDSVNTPQAG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 YFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFSLFF
::::: ::::. :.. :: :.:. :::.::: :::.: ::: :.: ::.: : ::::::
NP_872 YFGLFSYCVGNVLSS-ELICKGGPLDFSSIPSRAFKTAMFFVALGMFLIIGSIICFSLFF
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 FCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAY
.::::::::::::::: :: :..::...:::::. .: ::: .::::.:: :..:::.
NP_872 ICNTATVYKICAWMQLAAATGLMIGCLVYPDGWDSSEVRRMCGEQTGKYTLGHCTIRWAF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 ILAIIGILNALILSFLAFVLGNRQTDLLQEELKPENKDFVGSTVSSVLRPGGDVSGWGVL
.:::..: .:::::::::::: :: :: .. : .. . :
NP_872 MLAILSIGDALILSFLAFVLGYRQDKLLPDDYKADGTEEV
180 190 200 210
240
pF1KE2 PCPVAHSQGP
>>XP_016861849 (OMIM: 610240) PREDICTED: lipoma HMGIC fu (138 aa)
initn: 929 init1: 929 opt: 929 Z-score: 1209.5 bits: 230.4 E(85815): 1.3e-60
Smith-Waterman score: 929; 100.0% identity (100.0% similar) in 135 aa overlap (1-135:1-135)
10 20 30 40 50 60
pF1KE2 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFSLFFFCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFSLFFFCN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILA
:::::::::::::::
XP_016 TATVYKICAWMQLLAGGM
130
>>NP_005771 (OMIM: 606710) lipoma HMGIC fusion partner p (200 aa)
initn: 290 init1: 190 opt: 331 Z-score: 433.0 bits: 87.3 E(85815): 2.2e-17
Smith-Waterman score: 331; 29.9% identity (60.8% similar) in 194 aa overlap (23-201:9-195)
10 20 30 40 50 60
pF1KE2 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFG
::.::.... : . : :..:::. : . :: ::
NP_005 MASSLTCTGVIWALLSFLCAATSCVGFFMPYWLWGS-QLGKPVSFG
10 20 30 40
70 80 90 100
pF1KE2 LFHYC-VGSGLAGRELT-----CRGSFTDFSTIPSSAFK--------AAAFFVLLSMVLI
:. : .:.. : : ...:. :::. .. . ....:.... .
NP_005 TFRRCSYPVHDESRQMMVMVEEC-GRYASFQGIPSAEWRICTIVTGLGCGLLLLVALTAL
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE2 LGCITCFSLFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKY
.:: : : .. . :: .. . .:.:..: . :: ..: :::.: .:. :: .:..
NP_005 MGC--CVSDLI---SRTVGRVAGGIQFLGGLLIGAGCALYPLGWDSEEVRQTCGYTSGQF
110 120 130 140 150
170 180 190 200 210 220
pF1KE2 SLGDCSVRWAYILAIIGILNALIL-SFLAFVLGNRQTDLLQEELKPENKDFVGSTVSSVL
.:: : . ::: . : :..: ..:: :..:
NP_005 DLGKCEIGWAYYCTGAGATAAMLLCTWLACFSGKKQKHYPY
160 170 180 190 200
230 240
pF1KE2 RPGGDVSGWGVLPCPVAHSQGP
>>XP_011533163 (OMIM: 606710) PREDICTED: lipoma HMGIC fu (200 aa)
initn: 290 init1: 190 opt: 331 Z-score: 433.0 bits: 87.3 E(85815): 2.2e-17
Smith-Waterman score: 331; 29.9% identity (60.8% similar) in 194 aa overlap (23-201:9-195)
10 20 30 40 50 60
pF1KE2 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFG
::.::.... : . : :..:::. : . :: ::
XP_011 MASSLTCTGVIWALLSFLCAATSCVGFFMPYWLWGS-QLGKPVSFG
10 20 30 40
70 80 90 100
pF1KE2 LFHYC-VGSGLAGRELT-----CRGSFTDFSTIPSSAFK--------AAAFFVLLSMVLI
:. : .:.. : : ...:. :::. .. . ....:.... .
XP_011 TFRRCSYPVHDESRQMMVMVEEC-GRYASFQGIPSAEWRICTIVTGLGCGLLLLVALTAL
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE2 LGCITCFSLFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKY
.:: : : .. . :: .. . .:.:..: . :: ..: :::.: .:. :: .:..
XP_011 MGC--CVSDLI---SRTVGRVAGGIQFLGGLLIGAGCALYPLGWDSEEVRQTCGYTSGQF
110 120 130 140 150
170 180 190 200 210 220
pF1KE2 SLGDCSVRWAYILAIIGILNALIL-SFLAFVLGNRQTDLLQEELKPENKDFVGSTVSSVL
.:: : . ::: . : :..: ..:: :..:
XP_011 DLGKCEIGWAYYCTGAGATAAMLLCTWLACFSGKKQKHYPY
160 170 180 190 200
230 240
pF1KE2 RPGGDVSGWGVLPCPVAHSQGP
>>XP_006714578 (OMIM: 609718) PREDICTED: lipoma HMGIC fu (228 aa)
initn: 142 init1: 142 opt: 282 Z-score: 368.9 bits: 75.6 E(85815): 8.4e-14
Smith-Waterman score: 306; 26.8% identity (60.5% similar) in 228 aa overlap (14-217:3-225)
10 20 30 40 50
pF1KE2 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYW-VGDSVS-------
: . . :.. ::....: :. ....:.. : .: . :
XP_006 MCHVIVTCRSM--LWTLLSIVVAFAELIAFMSADWLIGKARSRGGVEPA
10 20 30 40
60 70 80 90 100
pF1KE2 -----TPKPGY--FGLFHYCV---GSGLAGRELTCRGSFTD-FSTIPSSAFKAAAFFVLL
.:.: . .:.. :. : :. : : ... :. : :. ..:.:.:. .
XP_006 GPGGGSPEPYHPTLGIYARCIRNPGVQHFQRDTLC-GPYAESFGEIASGFWQATAIFLAV
50 60 70 80 90 100
110 120 130 140 150
pF1KE2 SMVLILGCITCFSLFFFCNTA----TVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRD
. ..:: .. :.: .: . .....:. .: .:.: :.:: ...: :: . :
XP_006 G-IFILCMVALVSVFTMCVQSIMKKSIFNVCGLLQGIAGLFLILGLILYPAGWGCQKAID
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE2 MCGAKTGKYSLGDCSVRWAYILAIIG-ILNALILSFLAFVLGNRQTDLLQEELKPENKDF
.:: .. :. ::::. ::. :: : .:. . : : . ..: .:::.. :.:..
XP_006 YCGHYASAYKPGDCSLGWAFYTAIGGTVLTFICAVFSAQAEIATSSDKVQEEIE-EGKNL
170 180 190 200 210 220
220 230 240
pF1KE2 VGSTVSSVLRPGGDVSGWGVLPCPVAHSQGP
.
XP_006 ICLL
>>NP_005770 (OMIM: 609718) lipoma HMGIC fusion partner-l (228 aa)
initn: 142 init1: 142 opt: 282 Z-score: 368.9 bits: 75.6 E(85815): 8.4e-14
Smith-Waterman score: 306; 26.8% identity (60.5% similar) in 228 aa overlap (14-217:3-225)
10 20 30 40 50
pF1KE2 MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYW-VGDSVS-------
: . . :.. ::....: :. ....:.. : .: . :
NP_005 MCHVIVTCRSM--LWTLLSIVVAFAELIAFMSADWLIGKARSRGGVEPA
10 20 30 40
60 70 80 90 100
pF1KE2 -----TPKPGY--FGLFHYCV---GSGLAGRELTCRGSFTD-FSTIPSSAFKAAAFFVLL
.:.: . .:.. :. : :. : : ... :. : :. ..:.:.:. .
NP_005 GPGGGSPEPYHPTLGIYARCIRNPGVQHFQRDTLC-GPYAESFGEIASGFWQATAIFLAV
50 60 70 80 90 100
110 120 130 140 150
pF1KE2 SMVLILGCITCFSLFFFCNTA----TVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRD
. ..:: .. :.: .: . .....:. .: .:.: :.:: ...: :: . :
NP_005 G-IFILCMVALVSVFTMCVQSIMKKSIFNVCGLLQGIAGLFLILGLILYPAGWGCQKAID
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE2 MCGAKTGKYSLGDCSVRWAYILAIIG-ILNALILSFLAFVLGNRQTDLLQEELKPENKDF
.:: .. :. ::::. ::. :: : .:. . : : . ..: .:::.. :.:..
NP_005 YCGHYASAYKPGDCSLGWAFYTAIGGTVLTFICAVFSAQAEIATSSDKVQEEIE-EGKNL
170 180 190 200 210 220
220 230 240
pF1KE2 VGSTVSSVLRPGGDVSGWGVLPCPVAHSQGP
.
NP_005 ICLL
247 residues in 1 query sequences
61127809 residues in 85815 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Jan 20 09:29:43 2017 done: Fri Jan 20 09:29:44 2017
Total Scan time: 5.140 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]