Result of FASTA (ccds) for
pF1KE2655
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2655, 441 aa
1>>>pF1KE2655 441 - 441 aa - 441 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.0303+/-0.0011; mu= -15.1399+/- 0.067
mean_var=466.0518+/-93.912, 0's: 0 Z-trim(115.4): 14 B-trim: 0 in 0/54
Lambda= 0.059410
statistics sampled from 15981 (15993) to 15981 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.491), width: 16
Scan time: 3.900
The best scores are: opt bits E(32554)
CCDS11499.1 MAPT gene_id:4137|Hs108|chr17 ( 441) 2925 264.6 1.4e-70
CCDS45716.1 MAPT gene_id:4137|Hs108|chr17 ( 412) 2255 207.2 2.5e-53
CCDS11500.1 MAPT gene_id:4137|Hs108|chr17 ( 383) 2245 206.3 4.3e-53
CCDS56033.1 MAPT gene_id:4137|Hs108|chr17 ( 410) 2101 194.0 2.4e-49
CCDS11501.1 MAPT gene_id:4137|Hs108|chr17 ( 758) 2013 186.6 7.1e-47
CCDS45715.1 MAPT gene_id:4137|Hs108|chr17 ( 776) 1748 163.9 5e-40
CCDS11502.1 MAPT gene_id:4137|Hs108|chr17 ( 352) 1421 135.6 7.4e-32
CCDS33369.1 MAP2 gene_id:4133|Hs108|chr2 ( 559) 1096 107.9 2.6e-23
CCDS2385.1 MAP2 gene_id:4133|Hs108|chr2 ( 471) 857 87.4 3.3e-17
CCDS2384.1 MAP2 gene_id:4133|Hs108|chr2 (1827) 821 84.8 8e-16
CCDS46818.1 MAP4 gene_id:4134|Hs108|chr3 (1135) 694 73.7 1.1e-12
>>CCDS11499.1 MAPT gene_id:4137|Hs108|chr17 (441 aa)
initn: 2925 init1: 2925 opt: 2925 Z-score: 1380.7 bits: 264.6 E(32554): 1.4e-70
Smith-Waterman score: 2925; 100.0% identity (100.0% similar) in 441 aa overlap (1-441:1-441)
10 20 30 40 50 60
pF1KE2 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
370 380 390 400 410 420
430 440
pF1KE2 DSPQLATLADEVSASLAKQGL
:::::::::::::::::::::
CCDS11 DSPQLATLADEVSASLAKQGL
430 440
>>CCDS45716.1 MAPT gene_id:4137|Hs108|chr17 (412 aa)
initn: 2238 init1: 2238 opt: 2255 Z-score: 1070.8 bits: 207.2 E(32554): 2.5e-53
Smith-Waterman score: 2664; 93.4% identity (93.4% similar) in 441 aa overlap (1-441:1-412)
10 20 30 40 50 60
pF1KE2 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
::::::::::::: ::::::::::::::::::
CCDS45 SETSDAKSTPTAE-----------------------------AEEAGIGDTPSLEDEAAG
70 80 90
130 140 150 160 170 180
pF1KE2 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE2 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE2 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
340 350 360 370 380 390
430 440
pF1KE2 DSPQLATLADEVSASLAKQGL
:::::::::::::::::::::
CCDS45 DSPQLATLADEVSASLAKQGL
400 410
>>CCDS11500.1 MAPT gene_id:4137|Hs108|chr17 (383 aa)
initn: 2244 init1: 2244 opt: 2245 Z-score: 1066.6 bits: 206.3 E(32554): 4.3e-53
Smith-Waterman score: 2420; 86.8% identity (86.8% similar) in 441 aa overlap (1-441:1-383)
10 20 30 40 50 60
pF1KE2 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK----------------
10 20 30 40
70 80 90 100 110 120
pF1KE2 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
::::::::::::::::::
CCDS11 ------------------------------------------AEEAGIGDTPSLEDEAAG
50 60
130 140 150 160 170 180
pF1KE2 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE2 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE2 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE2 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE2 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
310 320 330 340 350 360
430 440
pF1KE2 DSPQLATLADEVSASLAKQGL
:::::::::::::::::::::
CCDS11 DSPQLATLADEVSASLAKQGL
370 380
>>CCDS56033.1 MAPT gene_id:4137|Hs108|chr17 (410 aa)
initn: 2099 init1: 1993 opt: 2101 Z-score: 999.5 bits: 194.0 E(32554): 2.4e-49
Smith-Waterman score: 2647; 93.0% identity (93.0% similar) in 441 aa overlap (1-441:1-410)
10 20 30 40 50 60
pF1KE2 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
:::::::::::::::::::::::::::::::::::::
CCDS56 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQI-----------------------
250 260 270
310 320 330 340 350 360
pF1KE2 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 --------VYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
280 290 300 310 320
370 380 390 400 410 420
pF1KE2 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
330 340 350 360 370 380
430 440
pF1KE2 DSPQLATLADEVSASLAKQGL
:::::::::::::::::::::
CCDS56 DSPQLATLADEVSASLAKQGL
390 400 410
>>CCDS11501.1 MAPT gene_id:4137|Hs108|chr17 (758 aa)
initn: 2816 init1: 2002 opt: 2013 Z-score: 955.0 bits: 186.6 E(32554): 7.1e-47
Smith-Waterman score: 2017; 73.2% identity (83.0% similar) in 441 aa overlap (12-441:319-758)
10 20 30
pF1KE2 MAEPRQEFEVMEDHAGTYGL----GDRKDQGGYTMHQD-QE
:.: : .. :. . : .. .: .:
CCDS11 VGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKE
290 300 310 320 330 340
40 50 60 70 80 90
pF1KE2 GDTDAGLKESPLQTPT-EDGSEEP---GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQ
.: ...: .: . :. : . .: .:. ..: : ... .: .
CCDS11 ADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSS-AKTLKNR
350 360 370 380 390 400
100 110 120 130 140 150
pF1KE2 P--HTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTK
: . : ... ..:.. : . . :.. ..:. . : ::::::::
CCDS11 PCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKYVSSVTSRTGSSGAKEMKLKGADGKTK
410 420 430 440 450 460
160 170 180 190 200 210
pF1KE2 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRS
470 480 490 500 510 520
220 230 240 250 260 270
pF1KE2 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQP
530 540 550 560 570 580
280 290 300 310 320 330
pF1KE2 GGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHH
590 600 610 620 630 640
340 350 360 370 380 390
pF1KE2 KPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGA
650 660 670 680 690 700
400 410 420 430 440
pF1KE2 EIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
710 720 730 740 750
>--
initn: 969 init1: 828 opt: 884 Z-score: 432.0 bits: 89.9 E(32554): 9.6e-18
Smith-Waterman score: 890; 55.1% identity (67.2% similar) in 296 aa overlap (1-275:1-289)
10 20 30 40 50 60
pF1KE2 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 HVTQARMVSKS-KDGTGSDDKKAKGADGKT-KIATPRGAAPPGQKGQANATRIPAKTPPA
:::: .: ..: . : : . .. . .:: .: .::: :. : :
CCDS11 HVTQEPESGKVVQEGF----LREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPE
130 140 150 160 170
180 190 200 210 220
pF1KE2 P----KTPPSSGEPPKSGDRSGYSSP--GSPGT--PGSR-----SRTPSLPTPPTREPKK
. : . :: . : :. : :::. .: . .: :.:
CCDS11 DTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSK
180 190 200 210 220 230
230 240 250 260 270
pF1KE2 VAVVRT--PPKSPSSAKSRLQTAP----VPMPDLKNVKSKIGSTENLKHQPGGGKVQIIN
.. .. ::.. . . . : .:.: . ::. ::: .: : .:
CCDS11 ASPAQDGRPPQTAAREATSIPGFPAEGAIPLP--VDFLSKV-STEIPASEPDGPSVGRAK
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE2 KKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEV
CCDS11 GQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPE
300 310 320 330 340 350
>>CCDS45715.1 MAPT gene_id:4137|Hs108|chr17 (776 aa)
initn: 2523 init1: 1709 opt: 1748 Z-score: 832.1 bits: 163.9 E(32554): 5e-40
Smith-Waterman score: 1971; 70.4% identity (79.7% similar) in 459 aa overlap (12-441:319-776)
10 20 30
pF1KE2 MAEPRQEFEVMEDHAGTYGL----GDRKDQGGYTMHQD-QE
:.: : .. :. . : .. .: .:
CCDS45 VGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKE
290 300 310 320 330 340
40 50 60 70 80 90
pF1KE2 GDTDAGLKESPLQTPT-EDGSEEP---GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQ
.: ...: .: . :. : . .: .:. ..: : ... .: .
CCDS45 ADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSS-AKTLKNR
350 360 370 380 390 400
100 110 120 130 140 150
pF1KE2 P--HTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTK
: . : ... ..:.. : . . :.. ..:. . : ::::::::
CCDS45 PCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKYVSSVTSRTGSSGAKEMKLKGADGKTK
410 420 430 440 450 460
160 170 180 190
pF1KE2 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSS------------------GEPPKSG
::::::::::::::::::::::::::::::::::: :::::::
CCDS45 IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSG
470 480 490 500 510 520
200 210 220 230 240 250
pF1KE2 DRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 DRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPD
530 540 550 560 570 580
260 270 280 290 300 310
pF1KE2 LKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKP
590 600 610 620 630 640
320 330 340 350 360 370
pF1KE2 VDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE
650 660 670 680 690 700
380 390 400 410 420 430
pF1KE2 THKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 THKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEV
710 720 730 740 750 760
440
pF1KE2 SASLAKQGL
:::::::::
CCDS45 SASLAKQGL
770
>--
initn: 969 init1: 828 opt: 884 Z-score: 431.9 bits: 89.9 E(32554): 9.8e-18
Smith-Waterman score: 890; 55.1% identity (67.2% similar) in 296 aa overlap (1-275:1-289)
10 20 30 40 50 60
pF1KE2 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 HVTQARMVSKS-KDGTGSDDKKAKGADGKT-KIATPRGAAPPGQKGQANATRIPAKTPPA
:::: .: ..: . : : . .. . .:: .: .::: :. : :
CCDS45 HVTQEPESGKVVQEGF----LREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPE
130 140 150 160 170
180 190 200 210 220
pF1KE2 P----KTPPSSGEPPKSGDRSGYSSP--GSPGT--PGSR-----SRTPSLPTPPTREPKK
. : . :: . : :. : :::. .: . .: :.:
CCDS45 DTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSK
180 190 200 210 220 230
230 240 250 260 270
pF1KE2 VAVVRT--PPKSPSSAKSRLQTAP----VPMPDLKNVKSKIGSTENLKHQPGGGKVQIIN
.. .. ::.. . . . : .:.: . ::. ::: .: : .:
CCDS45 ASPAQDGRPPQTAAREATSIPGFPAEGAIPLP--VDFLSKV-STEIPASEPDGPSVGRAK
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE2 KKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEV
CCDS45 GQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPE
300 310 320 330 340 350
>>CCDS11502.1 MAPT gene_id:4137|Hs108|chr17 (352 aa)
initn: 1418 init1: 1312 opt: 1421 Z-score: 685.4 bits: 135.6 E(32554): 7.4e-32
Smith-Waterman score: 2142; 79.8% identity (79.8% similar) in 441 aa overlap (1-441:1-352)
10 20 30 40 50 60
pF1KE2 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK----------------
10 20 30 40
70 80 90 100 110 120
pF1KE2 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
::::::::::::::::::
CCDS11 ------------------------------------------AEEAGIGDTPSLEDEAAG
50 60
130 140 150 160 170 180
pF1KE2 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE2 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE2 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHV
:::::::::::::::::::::::::::::::::::::
CCDS11 SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQI-----------------------
190 200 210
310 320 330 340 350 360
pF1KE2 PGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 --------VYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNI
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE2 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 THVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMV
280 290 300 310 320 330
430 440
pF1KE2 DSPQLATLADEVSASLAKQGL
:::::::::::::::::::::
CCDS11 DSPQLATLADEVSASLAKQGL
340 350
>>CCDS33369.1 MAP2 gene_id:4133|Hs108|chr2 (559 aa)
initn: 995 init1: 918 opt: 1096 Z-score: 532.1 bits: 107.9 E(32554): 2.6e-23
Smith-Waterman score: 1128; 44.6% identity (68.8% similar) in 462 aa overlap (23-441:107-559)
10 20 30 40
pF1KE2 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEG------DTDAGLKES
. .: ..:.:: . . :.: :
CCDS33 GELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPS
80 90 100 110 120 130
50 60 70 80 90 100
pF1KE2 PLQTPTEDGS----EEPGSETSDAKST-PTAEDVTAPLVDEGAPGKQAAAQ-PHTEIPEG
: .:. . . : :.:.. : :. :.: .. . :. :.... :.
CCDS33 PPPSPASEQTVTVEEAAGGESALAPSVFKQAKDKVSNSTLSKIPALQGSTKSPRYSSACP
140 150 160 170 180 190
110 120 130 140 150 160
pF1KE2 TTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPP
.:...: ..:. .. .:: :. ::: :. : .:. . .... : . ::
CCDS33 STTKRATFSDSLLIQPTSAGS-TDRLPYSKS----GNKDGVTKSPEKRSSLPRPSSILPP
200 210 220 230 240 250
170 180 190
pF1KE2 --GQKGQ------------ANATRIPAKTPP----------APKTPPSSGEPPKSGDRSG
: .:. ....: ... : .: :: :.. : : .
CCDS33 RRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITP--GTPPS
260 270 280 290 300
200 210 220 230 240
pF1KE2 YSS--PGSPGTPGSRSRTPSLPTPPTRE---P--KKVAVVRTPPKSPSSAKSRLQTAPVP
::: ::.:::: : ::: : : : ::::..:::::::.. : .:. :
CCDS33 YSSRTPGTPGTP-SYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPK-QLRLINQP
310 320 330 340 350 360
250 260 270 280 290 300
pF1KE2 MPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIV
.:::::::::::::.:.:.:: ::.:.:.:::.:.:.:::.::::::::: :::.::::
CCDS33 LPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIV
370 380 390 400 410 420
310 320 330 340 350 360
pF1KE2 YKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNK
: .:::.:::::::: ::.:.::::.:...: :::::...:.:.::::: :::::::
CCDS33 TKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNV
430 440 450 460 470 480
370 380 390 400 410 420
pF1KE2 KIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLA
::...::.:::.:::..::::::. .:: :. .:::.::::::.:::....::::::::
CCDS33 KIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLA
490 500 510 520 530 540
430 440
pF1KE2 DEVSASLAKQGL
..:.:.::::::
CCDS33 EDVTAALAKQGL
550
>>CCDS2385.1 MAP2 gene_id:4133|Hs108|chr2 (471 aa)
initn: 821 init1: 711 opt: 857 Z-score: 422.4 bits: 87.4 E(32554): 3.3e-17
Smith-Waterman score: 907; 39.1% identity (62.3% similar) in 483 aa overlap (11-441:31-471)
10 20 30 40
pF1KE2 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTD
..:..:. : : .. .:. ...:.::
CCDS23 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGA-GEGLVRSANGFPYREDEEGAFG
10 20 30 40 50
50 60 70 80 90
pF1KE2 AGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVD----------EGAPGKQAA
... .. :.: . : :: . : ::.:.: .:. .: :.:
CCDS23 EHGSQGTYSNTKENGIN--GELTSADRET--AEEVSARIVQVVTAEAVAVLKGEQEKEAQ
60 70 80 90 100 110
100 110 120 130
pF1KE2 AQPHTEIPEGTTAEEAGIGDTP----------SLEDEAAGHVTQARMVSK-SKDGTGSDD
. .: .. : :.. .: ..:. :.:. . : : : .:: . .:
CCDS23 HKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDKV--SD
120 130 140 150 160 170
140 150 160 170
pF1KE2 KKAKGADGKTKIATPRGAAPP--GQKGQ------------ANATRIPAKTPP--------
.:. . .... : . :: : .:. ....: ... :
CCDS23 GVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSG
180 190 200 210 220 230
180 190 200 210 220
pF1KE2 --APKTPPSSGEPPKSGDRSGYSS--PGSPGTPGSRSRTPSLPTPPTRE---P--KKVAV
.: :: :.. : : .::: ::.:::: : ::: : : : ::::.
CCDS23 TSTPTTPGSTAITP--GTPPSYSSRTPGTPGTP-SYPRTPHTPGTPKSAILVPSEKKVAI
240 250 260 270 280 290
230 240 250 260 270 280
pF1KE2 VRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQ
.:::::::.. : .:. :.:::::::::::::.:.:.:: ::.:::..::
CCDS23 IRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKK-------
300 310 320 330 340
290 300 310 320 330 340
pF1KE2 SKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKD
.:::.:::::::: ::.:.::::.:...: :::::.
CCDS23 ------------------------IDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKE
350 360 370
350 360 370 380 390 400
pF1KE2 RVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHL
..:.:.::::: ::::::: ::...::.:::.:::..::::::. .:: :. .:::.:
CCDS23 KAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRL
380 390 400 410 420 430
410 420 430 440
pF1KE2 SNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
:::::.:::....::::::::..:.:.::::::
CCDS23 SNVSSSGSINLLESPQLATLAEDVTAALAKQGL
440 450 460 470
>>CCDS2384.1 MAP2 gene_id:4133|Hs108|chr2 (1827 aa)
initn: 821 init1: 711 opt: 821 Z-score: 397.5 bits: 84.8 E(32554): 8e-16
Smith-Waterman score: 867; 43.3% identity (67.1% similar) in 365 aa overlap (84-441:1508-1827)
60 70 80 90 100 110
pF1KE2 DGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPS
: : ..: : . . .. :. .:
CCDS23 AHSPSRKFILKPAIKYTRPTHLSCVKRKTTAAGGESALAP-SVFKQAKDKVSDGVTKSP-
1480 1490 1500 1510 1520 1530
120 130 140 150 160 170
pF1KE2 LEDEAAGHVTQARMVSKSKDGTGSD-DKKAKGADGKTKIATPRGA-APPGQKGQANATRI
: . . . . . :...: :... . ... . .. : . . : ... ..:
CCDS23 ---EKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTST
1540 1550 1560 1570 1580 1590
180 190 200 210 220
pF1KE2 PAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTRE---P--KKV
:. :: . : : ::. ..:. ::.:::: : ::: : : : :::
CCDS23 PT-TPGSTAITP--GTPPSYSSRT----PGTPGTP-SYPRTPHTPGTPKSAILVPSEKKV
1600 1610 1620 1630 1640
230 240 250 260 270 280
pF1KE2 AVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSN
:..:::::::.. : .:. :.:::::::::::::.:.:.:: ::.:::..::
CCDS23 AIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKK-----
1650 1660 1670 1680 1690
290 300 310 320 330 340
pF1KE2 VQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDF
.:::.:::::::: ::.:.::::.:...: ::::
CCDS23 --------------------------IDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDF
1700 1710 1720 1730
350 360 370 380 390 400
pF1KE2 KDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPR
:...:.:.::::: ::::::: ::...::.:::.:::..::::::. .:: :. .:::
CCDS23 KEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPR
1740 1750 1760 1770 1780 1790
410 420 430 440
pF1KE2 HLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
.::::::.:::....::::::::..:.:.::::::
CCDS23 RLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL
1800 1810 1820
441 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 18 17:35:14 2016 done: Fri Nov 18 17:35:14 2016
Total Scan time: 3.900 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]