Result of FASTA (omim) for
pF1KE2585
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2585, 838 aa
1>>>pF1KE2585 838 - 838 aa - 838 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9020+/-0.000488; mu= 17.7181+/- 0.030
mean_var=82.0806+/-16.317, 0's: 0 Z-trim(109.8): 42 B-trim: 70 in 1/55
Lambda= 0.141564
statistics sampled from 18066 (18095) to 18066 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.563), E-opt: 0.2 (0.212), width: 16
Scan time: 9.190
The best scores are: opt bits E(85289)
NP_001123492 (OMIM: 192130) V-type proton ATPase 1 ( 838) 5623 1159.2 0
XP_005257516 (OMIM: 192130) PREDICTED: V-type prot ( 844) 5601 1154.7 0
NP_005168 (OMIM: 192130) V-type proton ATPase 116 ( 831) 5549 1144.1 0
NP_001123493 (OMIM: 192130) V-type proton ATPase 1 ( 837) 5527 1139.6 0
XP_016880255 (OMIM: 192130) PREDICTED: V-type prot ( 816) 5394 1112.4 0
XP_016880257 (OMIM: 192130) PREDICTED: V-type prot ( 803) 5342 1101.8 0
XP_016880256 (OMIM: 192130) PREDICTED: V-type prot ( 809) 5320 1097.3 0
XP_005257520 (OMIM: 192130) PREDICTED: V-type prot ( 784) 5061 1044.4 0
XP_005257518 (OMIM: 192130) PREDICTED: V-type prot ( 790) 5039 1039.9 0
XP_016880260 (OMIM: 192130) PREDICTED: V-type prot ( 777) 4987 1029.3 0
XP_016880259 (OMIM: 192130) PREDICTED: V-type prot ( 783) 4965 1024.8 0
XP_011523210 (OMIM: 192130) PREDICTED: V-type prot ( 802) 4547 939.4 0
XP_016880258 (OMIM: 192130) PREDICTED: V-type prot ( 795) 4473 924.3 0
XP_016880263 (OMIM: 192130) PREDICTED: V-type prot ( 575) 3862 799.4 0
XP_016880262 (OMIM: 192130) PREDICTED: V-type prot ( 581) 3840 794.9 0
XP_016880261 (OMIM: 192130) PREDICTED: V-type prot ( 581) 3840 794.9 0
NP_065683 (OMIM: 602722,605239) V-type proton ATPa ( 840) 3534 732.5 1.8e-210
XP_005250450 (OMIM: 602722,605239) PREDICTED: V-ty ( 840) 3534 732.5 1.8e-210
NP_570856 (OMIM: 602722,605239) V-type proton ATPa ( 840) 3534 732.5 1.8e-210
XP_005250451 (OMIM: 602722,605239) PREDICTED: V-ty ( 840) 3534 732.5 1.8e-210
NP_570855 (OMIM: 602722,605239) V-type proton ATPa ( 840) 3534 732.5 1.8e-210
XP_005273766 (OMIM: 259700,604592) PREDICTED: V-ty ( 830) 2162 452.3 4.1e-126
NP_006010 (OMIM: 259700,604592) V-type proton ATPa ( 830) 2162 452.3 4.1e-126
XP_011543028 (OMIM: 259700,604592) PREDICTED: V-ty ( 830) 2162 452.3 4.1e-126
XP_016872578 (OMIM: 259700,604592) PREDICTED: V-ty ( 805) 2045 428.4 6.3e-119
NP_006044 (OMIM: 259700,604592) V-type proton ATPa ( 614) 1982 415.5 3.7e-115
XP_016872579 (OMIM: 259700,604592) PREDICTED: V-ty ( 532) 1883 395.2 4e-109
NP_036595 (OMIM: 219200,278250,611716) V-type prot ( 856) 1830 384.5 1.1e-105
>>NP_001123492 (OMIM: 192130) V-type proton ATPase 116 k (838 aa)
initn: 5623 init1: 5623 opt: 5623 Z-score: 6205.2 bits: 1159.2 E(85289): 0
Smith-Waterman score: 5623; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KE2 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 QAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFFFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFFFF
730 740 750 760 770 780
790 800 810 820 830
pF1KE2 TAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
790 800 810 820 830
>>XP_005257516 (OMIM: 192130) PREDICTED: V-type proton A (844 aa)
initn: 5609 init1: 4781 opt: 5601 Z-score: 6180.9 bits: 1154.7 E(85289): 0
Smith-Waterman score: 5601; 99.3% identity (99.3% similar) in 844 aa overlap (1-838:1-844)
10 20 30 40 50 60
pF1KE2 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADE------FDF
::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_005 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEPSEDEVFDF
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 GDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGL
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 VLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREG
790 800 810 820 830 840
pF1KE2 KFEE
::::
XP_005 KFEE
>>NP_005168 (OMIM: 192130) V-type proton ATPase 116 kDa (831 aa)
initn: 4651 init1: 4651 opt: 5549 Z-score: 6123.6 bits: 1144.1 E(85289): 0
Smith-Waterman score: 5549; 99.2% identity (99.2% similar) in 838 aa overlap (1-838:1-831)
10 20 30 40 50 60
pF1KE2 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
::::::::::::::::::::: ::::::::::::::::::::::::::::::::
NP_005 NFLELTELKFILRKTQQFFDE-------MADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
130 140 150 160 170
190 200 210 220 230 240
pF1KE2 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE2 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVH
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE2 QAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFFFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFFFF
720 730 740 750 760 770
790 800 810 820 830
pF1KE2 TAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
780 790 800 810 820 830
>>NP_001123493 (OMIM: 192130) V-type proton ATPase 116 k (837 aa)
initn: 4637 init1: 3809 opt: 5527 Z-score: 6099.2 bits: 1139.6 E(85289): 0
Smith-Waterman score: 5527; 98.5% identity (98.5% similar) in 844 aa overlap (1-838:1-837)
10 20 30 40 50 60
pF1KE2 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
::::::::::::::::::::: ::::::::::::::::::::::::::::::::
NP_001 NFLELTELKFILRKTQQFFDE-------MADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
130 140 150 160 170
190 200 210 220 230 240
pF1KE2 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
600 610 620 630 640 650
670 680 690 700 710
pF1KE2 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADE------FDF
::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_001 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEPSEDEVFDF
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE2 GDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGL
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE2 VLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREG
780 790 800 810 820 830
pF1KE2 KFEE
::::
NP_001 KFEE
>>XP_016880255 (OMIM: 192130) PREDICTED: V-type proton A (816 aa)
initn: 5402 init1: 4781 opt: 5394 Z-score: 5952.6 bits: 1112.4 E(85289): 0
Smith-Waterman score: 5394; 99.3% identity (99.3% similar) in 814 aa overlap (1-808:1-814)
10 20 30 40 50 60
pF1KE2 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADE------FDF
::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_016 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEPSEDEVFDF
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 GDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGL
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 VLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREG
::::::::::::::::::::::::::::::::::
XP_016 VLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWSP
790 800 810
pF1KE2 KFEE
>>XP_016880257 (OMIM: 192130) PREDICTED: V-type proton A (803 aa)
initn: 4444 init1: 4444 opt: 5342 Z-score: 5895.3 bits: 1101.8 E(85289): 0
Smith-Waterman score: 5342; 99.1% identity (99.1% similar) in 808 aa overlap (1-808:1-801)
10 20 30 40 50 60
pF1KE2 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 NFLELTELKFILRKTQQFFDE-------MADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
130 140 150 160 170
190 200 210 220 230 240
pF1KE2 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE2 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVH
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE2 QAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFFFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFFFF
720 730 740 750 760 770
790 800 810 820 830
pF1KE2 TAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
::::::::::::::::::::::::::::
XP_016 TAFATLTVAILLIMEGLSAFLHALRLHWSP
780 790 800
>>XP_016880256 (OMIM: 192130) PREDICTED: V-type proton A (809 aa)
initn: 4430 init1: 3809 opt: 5320 Z-score: 5871.0 bits: 1097.3 E(85289): 0
Smith-Waterman score: 5320; 98.4% identity (98.4% similar) in 814 aa overlap (1-808:1-807)
10 20 30 40 50 60
pF1KE2 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 NFLELTELKFILRKTQQFFDE-------MADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
130 140 150 160 170
190 200 210 220 230 240
pF1KE2 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
600 610 620 630 640 650
670 680 690 700 710
pF1KE2 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADE------FDF
::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_016 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEPSEDEVFDF
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE2 GDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGL
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE2 VLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREG
::::::::::::::::::::::::::::::::::
XP_016 VLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWSP
780 790 800
pF1KE2 KFEE
>>XP_005257520 (OMIM: 192130) PREDICTED: V-type proton A (784 aa)
initn: 5061 init1: 5061 opt: 5061 Z-score: 5585.3 bits: 1044.4 E(85289): 0
Smith-Waterman score: 5061; 99.9% identity (100.0% similar) in 753 aa overlap (1-753:1-753)
10 20 30 40 50 60
pF1KE2 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 QAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFFFF
::::::::::::::::::::::::::::::.::
XP_005 QAIHTIEYCLGCISNTASYLRLWALSLAHARLSSRINSTAGPVSSSYPSPSSIFGKGSLK
730 740 750 760 770 780
790 800 810 820 830
pF1KE2 TAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
XP_005 SESL
>>XP_005257518 (OMIM: 192130) PREDICTED: V-type proton A (790 aa)
initn: 5047 init1: 4781 opt: 5039 Z-score: 5561.0 bits: 1039.9 E(85289): 0
Smith-Waterman score: 5039; 99.1% identity (99.2% similar) in 759 aa overlap (1-753:1-759)
10 20 30 40 50 60
pF1KE2 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADE------FDF
::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_005 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEPSEDEVFDF
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 GDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGL
::::::::::::::::::::::::::::::::::::.::
XP_005 GDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHARLSSRINSTAGPVSSSYPSPSSIF
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 VLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREG
XP_005 GKGSLKSESL
790
>>XP_016880260 (OMIM: 192130) PREDICTED: V-type proton A (777 aa)
initn: 4089 init1: 4089 opt: 4987 Z-score: 5503.7 bits: 1029.3 E(85289): 0
Smith-Waterman score: 4987; 98.9% identity (99.1% similar) in 753 aa overlap (1-753:1-746)
10 20 30 40 50 60
pF1KE2 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFLELTELKFILRKTQQFFDEAELHHQQMADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 NFLELTELKFILRKTQQFFDE-------MADPDLLEESSSLLEPSEMGRGTPLRLGFVAG
130 140 150 160 170
190 200 210 220 230 240
pF1KE2 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VINRERIPTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVW
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILN
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLN
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFGSSWSVRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLN
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLF
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE2 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVH
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE2 QAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLWTMVIHIGLSVKSLAGGLVLFFFF
::::::::::::::::::::::::::::::.::
XP_016 QAIHTIEYCLGCISNTASYLRLWALSLAHARLSSRINSTAGPVSSSYPSPSSIFGKGSLK
720 730 740 750 760 770
790 800 810 820 830
pF1KE2 TAFATLTVAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
XP_016 SESL
838 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:40:35 2016 done: Tue Nov 8 16:40:37 2016
Total Scan time: 9.190 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]