Result of FASTA (omim) for
pF1KE2576
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2576, 169 aa
1>>>pF1KE2576 169 - 169 aa - 169 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7112+/-0.000364; mu= 16.2023+/- 0.023
mean_var=81.2537+/-16.485, 0's: 0 Z-trim(114.3): 93 B-trim: 34 in 1/54
Lambda= 0.142283
statistics sampled from 23930 (24055) to 23930 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.282), width: 16
Scan time: 5.370
The best scores are: opt bits E(85289)
NP_000423 (OMIM: 160781,608758) myosin regulatory ( 166) 826 178.7 3.8e-45
NP_067046 (OMIM: 613993) myosin regulatory light c ( 175) 681 149.0 3.6e-36
XP_016863734 (OMIM: 160782) PREDICTED: myosin ligh ( 173) 672 147.1 1.3e-35
XP_016863735 (OMIM: 160782) PREDICTED: myosin ligh ( 173) 672 147.1 1.3e-35
NP_002468 (OMIM: 160782) myosin light chain 5 [Hom ( 173) 672 147.1 1.3e-35
XP_006713949 (OMIM: 160782) PREDICTED: myosin ligh ( 328) 665 146.0 5.3e-35
NP_001138416 (OMIM: 609211) myosin regulatory ligh ( 172) 600 132.3 3.6e-31
NP_291024 (OMIM: 609211) myosin regulatory light c ( 172) 600 132.3 3.6e-31
NP_001138417 (OMIM: 609211) myosin regulatory ligh ( 172) 600 132.3 3.6e-31
NP_006088 (OMIM: 609905) myosin regulatory light p ( 172) 590 130.3 1.5e-30
XP_011513766 (OMIM: 613993) PREDICTED: myosin regu ( 208) 549 122.0 5.8e-28
XP_016863736 (OMIM: 160782) PREDICTED: myosin ligh ( 132) 546 121.1 6.5e-28
XP_016863737 (OMIM: 160782) PREDICTED: myosin ligh ( 132) 546 121.1 6.5e-28
XP_016867967 (OMIM: 613993) PREDICTED: myosin regu ( 132) 494 110.5 1.1e-24
XP_011513767 (OMIM: 613993) PREDICTED: myosin regu ( 163) 494 110.6 1.2e-24
XP_011513765 (OMIM: 613993) PREDICTED: myosin regu ( 231) 438 99.2 4.5e-21
XP_016867968 (OMIM: 613993) PREDICTED: myosin regu ( 99) 412 93.5 1e-19
XP_005249874 (OMIM: 613993) PREDICTED: myosin regu ( 155) 383 87.8 8.6e-18
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 268 64.1 1.1e-10
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 268 64.1 1.1e-10
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 268 64.1 1.1e-10
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 268 64.1 1.1e-10
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 267 63.9 1.2e-10
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 267 63.9 1.2e-10
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 267 64.1 1.5e-10
NP_852667 (OMIM: 609905) myosin regulatory light p ( 118) 244 59.1 2.8e-09
NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo ( 167) 212 52.7 3.3e-07
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] ( 172) 210 52.3 4.5e-07
NP_002466 (OMIM: 609930) myosin light chain 6B [Ho ( 208) 210 52.4 5.1e-07
NP_001186558 (OMIM: 609930) myosin light chain 6B ( 208) 210 52.4 5.1e-07
NP_524147 (OMIM: 609931) myosin light polypeptide ( 151) 205 51.2 8.4e-07
NP_001284694 (OMIM: 602907) centrin-3 isoform 1 [H ( 191) 204 51.1 1.1e-06
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 198 49.8 2.5e-06
NP_066299 (OMIM: 609931) myosin light polypeptide ( 151) 196 49.4 3e-06
NP_524144 (OMIM: 160780) myosin light chain 1/3, s ( 194) 194 49.1 4.8e-06
NP_524146 (OMIM: 160780) myosin light chain 1/3, s ( 150) 186 47.3 1.3e-05
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 184 46.8 1.4e-05
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 184 46.8 1.4e-05
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 184 46.8 1.4e-05
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 184 46.8 1.4e-05
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 184 46.8 1.4e-05
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 184 46.8 1.4e-05
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 184 46.8 1.4e-05
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 167 43.4 0.0002
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 167 43.5 0.00021
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 167 43.5 0.00023
NP_062829 (OMIM: 607315) calcium-binding protein 5 ( 173) 162 42.4 0.00042
NP_057450 (OMIM: 607314,614899) calcium-binding pr ( 220) 163 42.8 0.00043
NP_001305425 (OMIM: 607314,614899) calcium-binding ( 226) 163 42.8 0.00043
XP_016882481 (OMIM: 607315) PREDICTED: calcium-bin ( 284) 162 42.7 0.00058
>>NP_000423 (OMIM: 160781,608758) myosin regulatory ligh (166 aa)
initn: 828 init1: 774 opt: 826 Z-score: 931.5 bits: 178.7 E(85289): 3.8e-45
Smith-Waterman score: 826; 71.3% identity (92.8% similar) in 167 aa overlap (1-167:1-166)
10 20 30 40 50 60
pF1KE2 MAPKRAKRRTVEGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRL
::::.::.:. :..:.:::::.::::::::::::..::::::.:::.::::::::.::.
NP_000 MAPKKAKKRA-GGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRV
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 NVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKKFL
::::::.: :.::: ::::::::::::::::::::::..: .::::.::::::..: ..
NP_000 NVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYV
60 70 80 90 100 110
130 140 150 160
pF1KE2 EELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE
.:.:::: .:::.::. .:.::::::: ::.::::. ..::::. .:
NP_000 REMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD
120 130 140 150 160
>>NP_067046 (OMIM: 613993) myosin regulatory light chain (175 aa)
initn: 707 init1: 674 opt: 681 Z-score: 770.4 bits: 149.0 E(85289): 3.6e-36
Smith-Waterman score: 681; 57.6% identity (86.7% similar) in 165 aa overlap (4-168:11-175)
10 20 30 40 50
pF1KE2 MAPKRAKRRTVEGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDT
: : . .. :::.:::::.:.:::::::::. ::::::::: : :::.:
NP_067 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 FAAMGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKG
.. .:...: .::::::..:..::::::::::.:::::.:.:::..: .::...:: :::
NP_067 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG
70 80 90 100 110 120
120 130 140 150 160
pF1KE2 TIKKKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE
...: ...:: :: :.:: :...:.: : :..::.:::..::.::::: ...
NP_067 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE
130 140 150 160 170
>>XP_016863734 (OMIM: 160782) PREDICTED: myosin light ch (173 aa)
initn: 713 init1: 659 opt: 672 Z-score: 760.5 bits: 147.1 E(85289): 1.3e-35
Smith-Waterman score: 672; 57.1% identity (84.6% similar) in 175 aa overlap (1-168:1-173)
10 20 30 40 50
pF1KE2 MAPKRAKRRTVEGG-------SSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDT
:: ...:.. ::: ::.::: :.::::::::::::..::::::.::::::.::
XP_016 MASRKTKKK--EGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDT
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 FAAMGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKG
.:..:. :::..:::::.::::::::::.::..:::::.:.: :..: .:::.:::.:::
XP_016 YASLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKG
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 TIKKKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE
:.:.....:: .: :... ::. .:. ::.::.::: . ::::::. ...
XP_016 KINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
120 130 140 150 160 170
>>XP_016863735 (OMIM: 160782) PREDICTED: myosin light ch (173 aa)
initn: 713 init1: 659 opt: 672 Z-score: 760.5 bits: 147.1 E(85289): 1.3e-35
Smith-Waterman score: 672; 57.1% identity (84.6% similar) in 175 aa overlap (1-168:1-173)
10 20 30 40 50
pF1KE2 MAPKRAKRRTVEGG-------SSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDT
:: ...:.. ::: ::.::: :.::::::::::::..::::::.::::::.::
XP_016 MASRKTKKK--EGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDT
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 FAAMGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKG
.:..:. :::..:::::.::::::::::.::..:::::.:.: :..: .:::.:::.:::
XP_016 YASLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKG
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 TIKKKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE
:.:.....:: .: :... ::. .:. ::.::.::: . ::::::. ...
XP_016 KINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
120 130 140 150 160 170
>>NP_002468 (OMIM: 160782) myosin light chain 5 [Homo sa (173 aa)
initn: 713 init1: 659 opt: 672 Z-score: 760.5 bits: 147.1 E(85289): 1.3e-35
Smith-Waterman score: 672; 57.1% identity (84.6% similar) in 175 aa overlap (1-168:1-173)
10 20 30 40 50
pF1KE2 MAPKRAKRRTVEGG-------SSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDT
:: ...:.. ::: ::.::: :.::::::::::::..::::::.::::::.::
NP_002 MASRKTKKK--EGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDT
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 FAAMGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKG
.:..:. :::..:::::.::::::::::.::..:::::.:.: :..: .:::.:::.:::
NP_002 YASLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKG
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 TIKKKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE
:.:.....:: .: :... ::. .:. ::.::.::: . ::::::. ...
NP_002 KINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE
120 130 140 150 160 170
>>XP_006713949 (OMIM: 160782) PREDICTED: myosin light ch (328 aa)
initn: 675 init1: 659 opt: 665 Z-score: 749.4 bits: 146.0 E(85289): 5.3e-35
Smith-Waterman score: 665; 56.9% identity (84.5% similar) in 174 aa overlap (2-168:157-328)
10 20
pF1KE2 MAPKRAKRRTVEGG-------SSSVFSMFDQ
: ...:.. ::: ::.::: :.:
XP_006 PPSASWPCVHTPDCGPGRTLSSCAERRRPEASRKTKKK--EGGALRAQRASSNVFSNFEQ
130 140 150 160 170 180
30 40 50 60 70 80
pF1KE2 TQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKEASGPINFTVFL
:::::::::::..::::::.::::::.::.:..:. :::..:::::.::::::::::.::
XP_006 TQIQEFKEAFTLMDQNRDGFIDKEDLKDTYASLGKTNVKDDELDAMLKEASGPINFTMFL
190 200 210 220 230 240
90 100 110 120 130 140
pF1KE2 TMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKKFLEELLTTQCDRFSQEEIKNMWAAFP
..:::::.:.: :..: .:::.:::.::: :.:.....:: .: :... ::. .:.
XP_006 NLFGEKLSGTDAEETILNAFKMLDPDGKGKINKEYIKRLLMSQADKMTAEEVDQMFQFAS
250 260 270 280 290 300
150 160
pF1KE2 PDVGGNVDYKNICYVITHGDAEDQE
::.::.::: . ::::::. ...
XP_006 IDVAGNLDYKALSYVITHGEEKEE
310 320
>>NP_001138416 (OMIM: 609211) myosin regulatory light ch (172 aa)
initn: 567 init1: 360 opt: 600 Z-score: 680.6 bits: 132.3 E(85289): 3.6e-31
Smith-Waterman score: 600; 54.3% identity (80.3% similar) in 173 aa overlap (1-169:1-171)
10 20 30 40 50
pF1KE2 MAPKRAKRRTVEG----GSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAA
:. :.:: .:.. ..:.::.::::.:::::::::..:::::::.::::::.: .:.
NP_001 MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 MGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIK
.:. : . :::::.:: ::::::.:::::::::.:.:::::: .:: .: :. :::.
NP_001 LGK-NPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQ
70 80 90 100 110
120 130 140 150 160
pF1KE2 KKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE
. .:.:::::. :::..::. ... : : :: .: .. .. :: :.:..
NP_001 EDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHG-AKDKDD
120 130 140 150 160 170
>>NP_291024 (OMIM: 609211) myosin regulatory light chain (172 aa)
initn: 567 init1: 360 opt: 600 Z-score: 680.6 bits: 132.3 E(85289): 3.6e-31
Smith-Waterman score: 600; 54.3% identity (80.3% similar) in 173 aa overlap (1-169:1-171)
10 20 30 40 50
pF1KE2 MAPKRAKRRTVEG----GSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAA
:. :.:: .:.. ..:.::.::::.:::::::::..:::::::.::::::.: .:.
NP_291 MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 MGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIK
.:. : . :::::.:: ::::::.:::::::::.:.:::::: .:: .: :. :::.
NP_291 LGK-NPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQ
70 80 90 100 110
120 130 140 150 160
pF1KE2 KKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE
. .:.:::::. :::..::. ... : : :: .: .. .. :: :.:..
NP_291 EDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHG-AKDKDD
120 130 140 150 160 170
>>NP_001138417 (OMIM: 609211) myosin regulatory light ch (172 aa)
initn: 567 init1: 360 opt: 600 Z-score: 680.6 bits: 132.3 E(85289): 3.6e-31
Smith-Waterman score: 600; 54.3% identity (80.3% similar) in 173 aa overlap (1-169:1-171)
10 20 30 40 50
pF1KE2 MAPKRAKRRTVEG----GSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAA
:. :.:: .:.. ..:.::.::::.:::::::::..:::::::.::::::.: .:.
NP_001 MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 MGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIK
.:. : . :::::.:: ::::::.:::::::::.:.:::::: .:: .: :. :::.
NP_001 LGK-NPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQ
70 80 90 100 110
120 130 140 150 160
pF1KE2 KKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE
. .:.:::::. :::..::. ... : : :: .: .. .. :: :.:..
NP_001 EDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHG-AKDKDD
120 130 140 150 160 170
>>NP_006088 (OMIM: 609905) myosin regulatory light polyp (172 aa)
initn: 573 init1: 349 opt: 590 Z-score: 669.5 bits: 130.3 E(85289): 1.5e-30
Smith-Waterman score: 590; 54.3% identity (80.3% similar) in 173 aa overlap (1-169:1-171)
10 20 30 40 50
pF1KE2 MAPKRAKRRTVEG----GSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAA
:. :::: .:.. ..:.::.::::.:::::::::..:::::::.::::::.: .:.
NP_006 MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 MGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIK
.:. : .: :..::.:: ::::::.:::::::::.:.:::::: .:: .: :..: :.
NP_006 LGK-NPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIH
70 80 90 100 110
120 130 140 150 160
pF1KE2 KKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE
. :.:::::. :::..::. .:. : : :: .: .. .. :: :.:..
NP_006 EDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHG-AKDKDD
120 130 140 150 160 170
169 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 18:10:53 2016 done: Fri Nov 4 18:10:54 2016
Total Scan time: 5.370 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]