Result of FASTA (omim) for
pF1KE2570
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2570, 526 aa
1>>>pF1KE2570 526 - 526 aa - 526 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.3473+/-0.000416; mu= -26.3667+/- 0.026
mean_var=395.0853+/-83.848, 0's: 0 Z-trim(121.8): 19 B-trim: 595 in 1/55
Lambda= 0.064525
statistics sampled from 39034 (39061) to 39034 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.458), width: 16
Scan time: 12.600
The best scores are: opt bits E(85289)
NP_005388 (OMIM: 602632) podocalyxin isoform 2 pre ( 526) 3360 326.9 9.2e-89
NP_001018121 (OMIM: 602632) podocalyxin isoform 1 ( 558) 1978 198.3 5.2e-50
NP_002448 (OMIM: 158370) mucin-2 precursor [Homo s (5289) 369 48.7 0.00051
NP_001291288 (OMIM: 158373) mucin-5AC precursor [H (5654) 333 45.4 0.0056
>>NP_005388 (OMIM: 602632) podocalyxin isoform 2 precurs (526 aa)
initn: 3360 init1: 3360 opt: 3360 Z-score: 1714.5 bits: 326.9 E(85289): 9.2e-89
Smith-Waterman score: 3360; 100.0% identity (100.0% similar) in 526 aa overlap (1-526:1-526)
10 20 30 40 50 60
pF1KE2 MRCALALSALLLLLSTPPLLPSSPSPSPSPSQNATQTTTDSSNKTAPTPASSVTIMATDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRCALALSALLLLLSTPPLLPSSPSPSPSPSQNATQTTTDSSNKTAPTPASSVTIMATDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AQQSTVPTSKANEILASVKATTLGVSSDSPGTTTLAQQVSGPVNTTVARGGGSGNPTTTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AQQSTVPTSKANEILASVKATTLGVSSDSPGTTTLAQQVSGPVNTTVARGGGSGNPTTTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ESPKSTKSADTTTVATSTATAKPNTTSSQNGAEDTTNSGGKSSHSVTTDLTSTKAEHLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ESPKSTKSADTTTVATSTATAKPNTTSSQNGAEDTTNSGGKSSHSVTTDLTSTKAEHLTT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 PHPTSPLSPRQPTSTHPVATPTSSGHDHLMKISSSSSTVAIPGYTFTSPGMTTTLPSSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PHPTSPLSPRQPTSTHPVATPTSSGHDHLMKISSSSSTVAIPGYTFTSPGMTTTLPSSVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SQRTQQTSSQMPASSTAPSSQETVQPTSPATALRTPTLPETMSSSPTAASTTHRYPKTPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SQRTQQTSSQMPASSTAPSSQETVQPTSPATALRTPTLPETMSSSPTAASTTHRYPKTPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 PTVAHESNWAKCEDLETQTQSEKQLVLNLTGNTLCAGGASDEKLISLICRAVKATFNPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PTVAHESNWAKCEDLETQTQSEKQLVLNLTGNTLCAGGASDEKLISLICRAVKATFNPAQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DKCGIRLASVPGSQTVVVKEITIHTKLPAKDVYERLKDKWDELKEAGVSDMKLGDQGPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DKCGIRLASVPGSQTVVVKEITIHTKLPAKDVYERLKDKWDELKEAGVSDMKLGDQGPPE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EAEDRFSMPLIITIVCMASFLLLVAALYGCCHQRLSQRKDQQRLTEELQTVENGYHDNPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EAEDRFSMPLIITIVCMASFLLLVAALYGCCHQRLSQRKDQQRLTEELQTVENGYHDNPT
430 440 450 460 470 480
490 500 510 520
pF1KE2 LEVMETSSEMQEKKVVSLNGELGDSWIVPLDNLTKDDLDEEEDTHL
::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LEVMETSSEMQEKKVVSLNGELGDSWIVPLDNLTKDDLDEEEDTHL
490 500 510 520
>>NP_001018121 (OMIM: 602632) podocalyxin isoform 1 prec (558 aa)
initn: 2074 init1: 1892 opt: 1978 Z-score: 1018.8 bits: 198.3 E(85289): 5.2e-50
Smith-Waterman score: 3276; 94.3% identity (94.3% similar) in 558 aa overlap (1-526:1-558)
10 20 30 40 50 60
pF1KE2 MRCALALSALLLLLSTPPLLPSSPSPSPSPSQNATQTTTDSSNKTAPTPASSVTIMATDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRCALALSALLLLLSTPPLLPSSPSPSPSPSQNATQTTTDSSNKTAPTPASSVTIMATDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AQQSTVPTSKANEILASVKATTLGVSSDSPGTTTLAQQVSGPVNTTVARGGGSGNPTTTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQQSTVPTSKANEILASVKATTLGVSSDSPGTTTLAQQVSGPVNTTVARGGGSGNPTTTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ESPKSTKSADTTTVATSTATAKPNTTSSQNGAEDTTNSGGKSSHSVTTDLTSTKAEHLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESPKSTKSADTTTVATSTATAKPNTTSSQNGAEDTTNSGGKSSHSVTTDLTSTKAEHLTT
130 140 150 160 170 180
190 200 210 220 230
pF1KE2 PHPTSPLSPRQPTSTHPVATPTSSGHDHLMKISSSSSTVAIPGYTFTSPGMTTTL-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHPTSPLSPRQPTSTHPVATPTSSGHDHLMKISSSSSTVAIPGYTFTSPGMTTTLLETVF
190 200 210 220 230 240
240 250 260
pF1KE2 ----------------P-----------SSVISQRTQQTSSQMPASSTAPSSQETVQPTS
: ::::::::::::::::::::::::::::::::
NP_001 HHVSQAGLELLTSGDLPTLASQSAGITASSVISQRTQQTSSQMPASSTAPSSQETVQPTS
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE2 PATALRTPTLPETMSSSPTAASTTHRYPKTPSPTVAHESNWAKCEDLETQTQSEKQLVLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PATALRTPTLPETMSSSPTAASTTHRYPKTPSPTVAHESNWAKCEDLETQTQSEKQLVLN
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE2 LTGNTLCAGGASDEKLISLICRAVKATFNPAQDKCGIRLASVPGSQTVVVKEITIHTKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTGNTLCAGGASDEKLISLICRAVKATFNPAQDKCGIRLASVPGSQTVVVKEITIHTKLP
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE2 AKDVYERLKDKWDELKEAGVSDMKLGDQGPPEEAEDRFSMPLIITIVCMASFLLLVAALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKDVYERLKDKWDELKEAGVSDMKLGDQGPPEEAEDRFSMPLIITIVCMASFLLLVAALY
430 440 450 460 470 480
450 460 470 480 490 500
pF1KE2 GCCHQRLSQRKDQQRLTEELQTVENGYHDNPTLEVMETSSEMQEKKVVSLNGELGDSWIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCCHQRLSQRKDQQRLTEELQTVENGYHDNPTLEVMETSSEMQEKKVVSLNGELGDSWIV
490 500 510 520 530 540
510 520
pF1KE2 PLDNLTKDDLDEEEDTHL
::::::::::::::::::
NP_001 PLDNLTKDDLDEEEDTHL
550
>>NP_002448 (OMIM: 158370) mucin-2 precursor [Homo sapie (5289 aa)
initn: 238 init1: 238 opt: 369 Z-score: 193.1 bits: 48.7 E(85289): 0.00051
Smith-Waterman score: 371; 31.4% identity (53.3% similar) in 287 aa overlap (15-301:1471-1723)
10 20 30 40
pF1KE2 MRCALALSALLLLLSTPPLLPSSPSPSPSPSQNATQTTTDSSNK
: : :: :. .::: : :::
NP_002 PITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPP---TTTTTTPPPT
1450 1460 1470 1480 1490
50 60 70 80 90 100
pF1KE2 TAPTPASSVTIMATDTAQQSTVPTSKANEILASVKATTLGVSSDSPGTTTLAQQVSGPVN
:.:.: ... : : :. .:.: . . ... .: ... :: ::: .. :..
NP_002 TTPSPPTTTPI--TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT---PITPPTS
1500 1510 1520 1530 1540 1550
110 120 130 140 150 160
pF1KE2 TTVARGGGSGNPTTTIESPKSTKSADTTTVATSTATAKPNTTSSQNGAEDTTNSGGKSSH
::. : :: :: : :::. :.: .: ::.. . ::.. ..
NP_002 TTTL-------PPTTTPSPPPT----TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTT-
1560 1570 1580 1590 1600
170 180 190 200 210 220
pF1KE2 SVTTDLTSTKAEHLTTPHPTSPLSPRQPTSTHPVATPTSSGHDHLMKISSSSSTVAIPGY
. . :.: ::: ::. .: ::.: :.. :::. . ... :
NP_002 TPSPPTTTT-----TTPPPTT--TPSPPTTT-PITPPTST-----TTLPPTTTPSPPPTT
1610 1620 1630 1640
230 240 250 260 270 280
pF1KE2 TFTSPGMTTTLPSSVISQRTQQTSSQMPASSTAPSSQETVQPTSPATALRTPTLPETMSS
: : : :: : .. . :.. : .:.::: :. :. :.:.. ::. : : :
NP_002 TTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPS-PTTTPS
1650 1660 1670 1680 1690 1700
290 300 310 320 330 340
pF1KE2 SPTAASTTHRYPKTPSPTVAHESNWAKCEDLETQTQSEKQLVLNLTGNTLCAGGASDEKL
:: ...:: ::::
NP_002 SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSIT
1710 1720 1730 1740 1750 1760
>>NP_001291288 (OMIM: 158373) mucin-5AC precursor [Homo (5654 aa)
initn: 251 init1: 194 opt: 333 Z-score: 174.5 bits: 45.4 E(85289): 0.0056
Smith-Waterman score: 333; 28.6% identity (61.6% similar) in 294 aa overlap (15-301:4122-4411)
10 20 30 40
pF1KE2 MRCALALSALLLLLSTPPLLPSSPSPSPSPSQNATQ-TTTDSSN
.. : .. .:. : .. :. ::. ..
NP_001 LVTTSTTSTPQTSTTSAPTTSTIPASTPSTTSAPTTSTTSAPTTSTTSAPTHRTTSGPTT
4100 4110 4120 4130 4140 4150
50 60 70 80 90 100
pF1KE2 KTAPTPASSVTIMATDTAQQSTVPTSKANEILASVKA-TTLGVSSDSPGTTTLAQ--QVS
.:. .:..:.: : ..... . .. . ....: :: .:: . .::. : ..:
NP_001 STTLAPTTSTTSAPTTSTNSAPTTSTISASTTSTISAPTTSTISSPTSSTTSTPQTSKTS
4160 4170 4180 4190 4200 4210
110 120 130 140 150 160
pF1KE2 GPVNTTVARGGGSGNPTTTIESPKSTKSADTTTVATSTATAKPNTTSSQNGAEDTTNSGG
. ...:.. .: . .:. : : :.....::.. :...:. :.:: : . .::...
NP_001 AATSSTTSGSGTTPSPVPTT-STTSASTTSTTSAPTTSTTSGPGTTPSPVPSTSTTSAAT
4220 4230 4240 4250 4260 4270
170 180 190 200 210
pF1KE2 KSSHSV-TTDLTSTKAEHLTTPHPTSPLSPRQPTSTHPV-ATPTSSGHDHLMKISSSSST
:. :. :: ::. . .:. :.: :: ::: . .: :.:: . ..::
NP_001 TSTTSAPTTRTTSAPTSSMTSGPGTTP-SPVPTTSTTSAPTTSTTSGPGTTPSPVPTTST
4280 4290 4300 4310 4320
220 230 240 250 260 270
pF1KE2 VAIPGYTFTS-PGMTTTLPSSVISQRTQQTSSQMPASSTAPSSQETVQPTSPATALRTPT
.. : . :: :: : . : . : . :.: ::... .: . : ::. . : .
NP_001 TSAPITSTTSGPGSTPS-PVPTTSTTSAPTTSTTSASTASTTSGPGTTP-SPVPTTSTTS
4330 4340 4350 4360 4370 4380
280 290 300 310 320 330
pF1KE2 LPETMSSSPTAASTTHRYPKTPSPTVAHESNWAKCEDLETQTQSEKQLVLNLTGNTLCAG
: : ..: ..:::: .::::
NP_001 APTTRTTSASTASTTSGPGSTPSPVPTTSTTSAPTTRTTPASTASTTSGPGTTPSPVPTT
4390 4400 4410 4420 4430 4440
526 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:09:05 2016 done: Sun Nov 6 22:09:07 2016
Total Scan time: 12.600 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]