Result of FASTA (omim) for
pF1KE2567
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2567, 743 aa
1>>>pF1KE2567 743 - 743 aa - 743 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.4477+/-0.000389; mu= -7.9944+/- 0.024
mean_var=347.6252+/-73.830, 0's: 0 Z-trim(122.1): 190 B-trim: 2126 in 1/57
Lambda= 0.068789
statistics sampled from 39477 (39681) to 39477 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.465), width: 16
Scan time: 11.400
The best scores are: opt bits E(85289)
NP_003251 (OMIM: 601041) transducin-like enhancer ( 743) 5029 513.4 1.3e-144
NP_001287775 (OMIM: 601041) transducin-like enhanc ( 744) 5017 512.2 3.1e-144
XP_006722927 (OMIM: 601041) PREDICTED: transducin- ( 693) 4614 472.2 3.2e-132
NP_001138233 (OMIM: 601041) transducin-like enhanc ( 706) 4549 465.7 2.8e-130
NP_001138234 (OMIM: 601041) transducin-like enhanc ( 621) 3782 389.6 2.1e-107
XP_006717323 (OMIM: 600189) PREDICTED: transducin- ( 740) 2921 304.2 1.3e-81
XP_016870570 (OMIM: 605132) PREDICTED: transducin- ( 748) 2831 295.2 6.3e-79
XP_016870569 (OMIM: 605132) PREDICTED: transducin- ( 749) 2821 294.3 1.2e-78
NP_001269678 (OMIM: 605132) transducin-like enhanc ( 748) 2814 293.6 2e-78
XP_016870571 (OMIM: 605132) PREDICTED: transducin- ( 747) 2770 289.2 4.2e-77
XP_016870566 (OMIM: 605132) PREDICTED: transducin- ( 753) 2685 280.8 1.4e-74
XP_016870567 (OMIM: 605132) PREDICTED: transducin- ( 752) 2681 280.4 1.9e-74
NP_001290033 (OMIM: 600189) transducin-like enhanc ( 755) 2676 279.9 2.7e-74
XP_005254690 (OMIM: 600190) PREDICTED: transducin- ( 755) 2667 279.0 5e-74
NP_001269911 (OMIM: 600190) transducin-like enhanc ( 699) 2653 277.6 1.2e-73
XP_005254685 (OMIM: 600190) PREDICTED: transducin- ( 765) 2653 277.6 1.3e-73
XP_016870568 (OMIM: 605132) PREDICTED: transducin- ( 750) 2630 275.3 6.3e-73
XP_016870564 (OMIM: 605132) PREDICTED: transducin- ( 758) 2563 268.7 6.4e-71
XP_011526532 (OMIM: 601041) PREDICTED: transducin- ( 732) 2544 266.8 2.3e-70
XP_016870565 (OMIM: 605132) PREDICTED: transducin- ( 756) 2512 263.6 2.1e-69
NP_065959 (OMIM: 600190) transducin-like enhancer ( 760) 2500 262.4 4.9e-69
XP_005254682 (OMIM: 600190) PREDICTED: transducin- ( 770) 2500 262.4 5e-69
XP_005254680 (OMIM: 600190) PREDICTED: transducin- ( 774) 2493 261.7 8.1e-69
XP_006720728 (OMIM: 600190) PREDICTED: transducin- ( 763) 2492 261.6 8.5e-69
NP_001269908 (OMIM: 600190) transducin-like enhanc ( 764) 2492 261.6 8.5e-69
XP_011520280 (OMIM: 600190) PREDICTED: transducin- ( 777) 2351 247.6 1.4e-64
NP_001269909 (OMIM: 600190) transducin-like enhanc ( 767) 2350 247.5 1.5e-64
XP_011520281 (OMIM: 600190) PREDICTED: transducin- ( 710) 2345 247.0 2e-64
XP_011520285 (OMIM: 600190) PREDICTED: transducin- ( 693) 2330 245.5 5.5e-64
XP_005252220 (OMIM: 600189) PREDICTED: transducin- ( 696) 2313 243.8 1.8e-63
XP_016870555 (OMIM: 600189) PREDICTED: transducin- ( 724) 2313 243.8 1.8e-63
XP_011517253 (OMIM: 600189) PREDICTED: transducin- ( 769) 2313 243.9 1.9e-63
NP_005068 (OMIM: 600189) transducin-like enhancer ( 770) 2313 243.9 1.9e-63
XP_016870553 (OMIM: 600189) PREDICTED: transducin- ( 779) 2313 243.9 1.9e-63
NP_001290032 (OMIM: 600189) transducin-like enhanc ( 780) 2313 243.9 1.9e-63
XP_006717326 (OMIM: 600189) PREDICTED: transducin- ( 768) 2308 243.4 2.7e-63
XP_006717325 (OMIM: 600189) PREDICTED: transducin- ( 769) 2308 243.4 2.7e-63
XP_016870554 (OMIM: 600189) PREDICTED: transducin- ( 778) 2308 243.4 2.7e-63
XP_005252213 (OMIM: 600189) PREDICTED: transducin- ( 779) 2308 243.4 2.7e-63
XP_005252209 (OMIM: 600189) PREDICTED: transducin- ( 813) 2281 240.7 1.8e-62
XP_006717324 (OMIM: 600189) PREDICTED: transducin- ( 699) 2274 240.0 2.6e-62
XP_005252219 (OMIM: 600189) PREDICTED: transducin- ( 730) 2274 240.0 2.7e-62
XP_006717322 (OMIM: 600189) PREDICTED: transducin- ( 758) 2274 240.0 2.8e-62
XP_005252211 (OMIM: 600189) PREDICTED: transducin- ( 803) 2274 240.0 2.9e-62
XP_005252210 (OMIM: 600189) PREDICTED: transducin- ( 804) 2274 240.0 2.9e-62
XP_006717321 (OMIM: 600189) PREDICTED: transducin- ( 813) 2274 240.0 2.9e-62
XP_005252208 (OMIM: 600189) PREDICTED: transducin- ( 814) 2274 240.0 2.9e-62
XP_005254679 (OMIM: 600190) PREDICTED: transducin- ( 779) 2246 237.2 1.9e-61
NP_001269910 (OMIM: 600190) transducin-like enhanc ( 762) 2245 237.1 2e-61
NP_001098662 (OMIM: 600190) transducin-like enhanc ( 769) 2245 237.1 2.1e-61
>>NP_003251 (OMIM: 601041) transducin-like enhancer prot (743 aa)
initn: 5029 init1: 5029 opt: 5029 Z-score: 2716.9 bits: 513.4 E(85289): 1.3e-144
Smith-Waterman score: 5029; 100.0% identity (100.0% similar) in 743 aa overlap (1-743:1-743)
10 20 30 40 50 60
pF1KE2 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LIGQQLQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAAVKEDRAGVEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LIGQQLQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAAVKEDRAGVEAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GSRVERAPSRSASPSPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GSRVERAPSRSASPSPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 EDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHST
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LNGDLSVPSSYVSLHLSPQVSSSVVYGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNGDLSVPSSYVSLHLSPQVSSSVVYGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAYS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 KVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 AELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 GTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 KPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDI
670 680 690 700 710 720
730 740
pF1KE2 SRNNKYIVTGSGDKKATVYEVVY
:::::::::::::::::::::::
NP_003 SRNNKYIVTGSGDKKATVYEVVY
730 740
>>NP_001287775 (OMIM: 601041) transducin-like enhancer p (744 aa)
initn: 4211 init1: 4211 opt: 5017 Z-score: 2710.5 bits: 512.2 E(85289): 3.1e-144
Smith-Waterman score: 5017; 99.9% identity (99.9% similar) in 744 aa overlap (1-743:1-744)
10 20 30 40 50 60
pF1KE2 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNS
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 LIGQQ-LQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAAVKEDRAGVEA
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIGQQQLQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAAVKEDRAGVEA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 EGSRVERAPSRSASPSPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGSRVERAPSRSASPSPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 DEDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 ASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 TLNGDLSVPSSYVSLHLSPQVSSSVVYGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLNGDLSVPSSYVSLHLSPQVSSSVVYGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 SFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGC
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 VKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 KAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISD
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 YGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHV
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 RKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCD
670 680 690 700 710 720
720 730 740
pF1KE2 ISRNNKYIVTGSGDKKATVYEVVY
::::::::::::::::::::::::
NP_001 ISRNNKYIVTGSGDKKATVYEVVY
730 740
>>XP_006722927 (OMIM: 601041) PREDICTED: transducin-like (693 aa)
initn: 3808 init1: 3808 opt: 4614 Z-score: 2494.8 bits: 472.2 E(85289): 3.2e-132
Smith-Waterman score: 4614; 99.9% identity (99.9% similar) in 683 aa overlap (1-682:1-683)
10 20 30 40 50 60
pF1KE2 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNS
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 LIGQQ-LQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAAVKEDRAGVEA
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIGQQQLQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAAVKEDRAGVEA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 EGSRVERAPSRSASPSPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGSRVERAPSRSASPSPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 DEDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 ASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 TLNGDLSVPSSYVSLHLSPQVSSSVVYGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLNGDLSVPSSYVSLHLSPQVSSSVVYGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 SFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGC
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 VKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRI
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 KAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISD
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 YGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHV
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 RKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCD
:::::::::::::::::::::::
XP_006 RKPEKYQLHLHESCVLSLKFASCVQGVVLSPEL
670 680 690
>>NP_001138233 (OMIM: 601041) transducin-like enhancer p (706 aa)
initn: 3808 init1: 3808 opt: 4549 Z-score: 2459.8 bits: 465.7 E(85289): 2.8e-130
Smith-Waterman score: 4549; 99.1% identity (99.3% similar) in 681 aa overlap (3-682:16-696)
10 20 30 40
pF1KE2 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECE
: . :::::::::::::::::::::::::::::::::::::::
NP_001 MVQSRLTATSASQDSPASGLQTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 KLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 ERAKQVTVGELNSLIGQQ-LQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQL
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 ERAKQVTVGELNSLIGQQQLQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 AAAVKEDRAGVEAEGSRVERAPSRSASPSPPESLVEEERPSGPGGGGKQRADEKEPSGPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAVKEDRAGVEAEGSRVERAPSRSASPSPPESLVEEERPSGPGGGGKQRADEKEPSGPY
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 ESDEDKSDYNLVVDEDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESDEDKSDYNLVVDEDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSLGSPLPRA
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE2 KELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVALRSPLTLS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE2 SPFTTSFSLGSHSTLNGDLSVPSSYVSLHLSPQVSSSVVYGRSPVMAFESHPHLRGSSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPFTTSFSLGSHSTLNGDLSVPSSYVSLHLSPQVSSSVVYGRSPVMAFESHPHLRGSSVS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE2 SSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTIS
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE2 GSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEAST
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE2 LSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQ
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE2 GHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLA
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE2 VGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASI
::::::::::::::::::::::::::::::::::::
NP_001 VGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCVQGVVLSPEL
670 680 690 700
710 720 730 740
pF1KE2 FQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY
>>NP_001138234 (OMIM: 601041) transducin-like enhancer p (621 aa)
initn: 4208 init1: 3782 opt: 3782 Z-score: 2049.2 bits: 389.6 E(85289): 2.1e-107
Smith-Waterman score: 4078; 90.3% identity (90.3% similar) in 688 aa overlap (56-743:1-621)
30 40 50 60 70 80
pF1KE2 DRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLS
::::::::::::::::::::::::::::::
NP_001 MQRHYVMYYEMSYGLNIEMHKQAEIVKRLS
10 20 30
90 100 110 120 130 140
pF1KE2 GICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIGQQLQPLSHHAPPVPLTPRPAGL
::::::::::::::::::::::::::::::::::::::
NP_001 GICAQIIPFLTQEHQQQVLQAVERAKQVTVGELNSLIG----------------------
40 50 60
150 160 170 180 190 200
pF1KE2 VGGSATGLLALSGALAAQAQLAAAVKEDRAGVEAEGSRVERAPSRSASPSPPESLVEEER
:::::::::::::::
NP_001 ---------------------------------------------SASPSPPESLVEEER
70 80
210 220 230 240 250 260
pF1KE2 PSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKVPICIPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKVPICIPAR
90 100 110 120 130 140
270 280 290 300 310 320
pF1KE2 RDLVDSPASLASSLGSPLPRAKELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLVDSPASLASSLGSPLPRAKELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQ
150 160 170 180 190 200
330 340 350 360 370 380
pF1KE2 LAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHSTLNGDLSVPSSYVSLHLSPQVSSSVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHSTLNGDLSVPSSYVSLHLSPQVSSSVV
210 220 230 240 250 260
390 400 410 420 430 440
pF1KE2 YGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIP
270 280 290 300 310 320
450 460 470 480 490 500
pF1KE2 RHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNY
330 340 350 360 370 380
510 520 530 540 550 560
pF1KE2 IRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSC
390 400 410 420 430 440
570 580 590 600 610 620
pF1KE2 CSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQ
450 460 470 480 490 500
630 640 650 660 670 680
pF1KE2 QHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRW
510 520 530 540 550 560
690 700 710 720 730 740
pF1KE2 FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY
570 580 590 600 610 620
>>XP_006717323 (OMIM: 600189) PREDICTED: transducin-like (740 aa)
initn: 3006 init1: 2160 opt: 2921 Z-score: 1586.4 bits: 304.2 E(85289): 1.3e-81
Smith-Waterman score: 3008; 61.1% identity (74.9% similar) in 800 aa overlap (1-743:1-740)
10 20 30 40 50
pF1KE2 MYPQGRHPTPLQS-GQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH
:.::.::::: :. ::::::.: : ::::::::::::::::::::::::::::::::::
XP_006 MFPQSRHPTPHQAAGQPFKFTIPESLDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 YVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTVGELN
::::::::::::::::::.::.:::. ::::.::::.::::::: ::::::::::..:::
XP_006 YVMYYEMSYGLNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 SLIGQQLQPLSHHAPPVPLTPRPAGLVGGSATGLLALSGALAAQAQLAAAVKEDRAGVEA
..:: . : ::
XP_006 AIIGVRGLP---------------GL----------------------------------
130
180 190 200 210 220 230
pF1KE2 EGSRVERAPSRSASPSPPESLV-EEERPSGPGGGG---KQRADEKEPSGPYESDEDKSDY
: : : :.:: ..: .:: .. :...:.:. :. :.:: ::::
XP_006 --------PPTSNSLLVPDSLRGTDKRRNGPEFSNDIKKRKVDDKD-SSHYDSDGDKSDD
140 150 160 170 180
240 250 260 270 280 290
pF1KE2 NLVVD--EDQPSEP-PSPATTP-CGKVPICIPARRDLVDSPASLASSLGSPLPRAKELIL
::::: ...:: : ::: .: . . ..: .:::: ::: .: ..::. :
XP_006 NLVVDVSNEDPSSPRASPAHSPRENGIDKNRLLKKDASSSPASTASSASSTSLKSKEMSL
190 200 210 220 230 240
300 310 320 330
pF1KE2 NDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTD----------------
.. ::::. :: .: .: ::: :.. : .:: :. :
XP_006 HE-KASTPVLKSSTPTPRSDMPTPGTSATPGLRPGLGKP-PAIDPLVNQAGLDFHLELVP
250 260 270 280 290 300
340 350 360 370
pF1KE2 ------------------------SVALRSPLTLSSPFTTSFSLGSHSTLNGDLSVP-SS
...::.::.. .:. . :.. :. .::.:. : ..
XP_006 GNGKFGLKEKSWILSRKSSFEIKSAAGLRTPLAVPGPYPAPFGMVPHAGMNGELTSPGAA
310 320 330 340 350 360
380 390 400 410 420
pF1KE2 YVSLH-LSPQVSSS------VVYGRSPVMAFESHPHLRGSSVSSSLPSIPGGKPAYSFHV
:.::: .:::.:.. :.:::::...:. ::.: .. .: .::::::::::::
XP_006 YASLHNMSPQMSAAAAAAAVVAYGRSPMVGFDPPPHMRVPTIPPNLAGIPGGKPAYSFHV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVW
.::::::::::: :::.: ::::::::..:: :::::::::::. :.:::::::::::::
XP_006 TADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAEL
:...:: :.::.:::::::::::::::::::: .::::::::::::::::::::::::::
XP_006 DISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAEL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTR
:::::::::::.:::.::::::::::::.::::.:::.:::::::::::::::::. ::.
XP_006 TSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPE
::::::::::: ::::::::::::::.:::::::.::. .::::::::::::.::: ::.
XP_006 LWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNKPD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 KYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRN
::::::::::::::::: ::.::::::::::::::::::::::::::::::::::::: .
XP_006 KYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVD
670 680 690 700 710 720
730 740
pF1KE2 NKYIVTGSGDKKATVYEVVY
.:::::::::::::::::.:
XP_006 DKYIVTGSGDKKATVYEVIY
730 740
>>XP_016870570 (OMIM: 605132) PREDICTED: transducin-like (748 aa)
initn: 3218 init1: 2040 opt: 2831 Z-score: 1538.0 bits: 295.2 E(85289): 6.3e-79
Smith-Waterman score: 3153; 63.1% identity (78.1% similar) in 793 aa overlap (1-743:8-748)
10 20 30 40 50
pF1KE2 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEK
:::: :::.: : .:::::.: : :::::::::::::::::::::::::::::
XP_016 MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 TEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQV
:::::::::::::::::::::::::::::::..::::.::::.:::::::.:::::::::
XP_016 TEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEHQQQVVQAVERAKQV
70 80 90 100 110 120
120 130 140 150 160
pF1KE2 TVGELNSLIGQQL---QPLSH-HAPPVPLTPRPAGLVG------GSATGLLALSGALAAQ
:..:::..:::: : ::: :. ::::::.:.:: ::..::::::.::..:
XP_016 TMAELNAIIGQQQLQAQHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQ
130 140 150 160 170 180
170 180 190 200 210
pF1KE2 AQLAAAVKEDRAGVEAEGSRVERAPSRSASPSPPESL--VEEERPSGPGGG--GKQRADE
..: .:... . . .: .: .:.: :: :. .:..: :. .. ::...:
XP_016 SHLP--IKDEKKHHDNDHQR-DRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEE
190 200 210 220 230
220 230 240 250 260 270
pF1KE2 KEPSGPYESDEDKSDYNLVVDEDQPSEPPSPATTPCGKVPICIPARRDLVDSPASLASSL
:: .. :.:: .::: ::::: .. .:
XP_016 KEIAARYDSDGEKSDDNLVVDVSNENEK--------------------------------
240 250 260
280 290 300 310 320 330
pF1KE2 GSPLPRAKELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVA-
..::.::: .: :: ::: .:. : . .:: :..: .:
XP_016 ----------------STTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKP-PGVDPLAS
270 280 290 300
340 350 360 370 380
pF1KE2 -LRSPLTLSSPFTTSFSLGSHSTLNGDLSVP-SSYVSLH-LSPQVSSSVV-------YGR
::.:... :. : :.. :. .::.:. : ..:..:: .:::.:.... :::
XP_016 SLRTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGR
310 320 330 340 350 360
390 400 410 420
pF1KE2 SPVMAFESHPHLRGSSVSSSLPSIPGGKP-------------------------AYSFHV
:::..:. : :.: .. .: .:::::: ::::::
XP_016 SPVVGFDPHHHMRVPAIPPNLTGIPGGKPTKCFYHLRAFPGNELEMELPRDTHRAYSFHV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SADGQMQPVPFPSDALVGAGIPRHARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVW
:::::::::::: :::.: ::::::::..:: :::::::::::. :.:::::::::::::
XP_016 SADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DVGQPGAKTPVAQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAEL
:...:: :.::.::::::::::::::.::::::.::::::::::::::::::::::::::
XP_016 DISHPGNKSPVSQLDCLNRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAEL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTR
:::::::::::.:::.::::::::::::.::::.:::.:::::::::::::::::. ::.
XP_016 TSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LWTGGLDNTVRCWDLREGRQLQQHDFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPE
::::::::::: ::::::::::::::.:::::::.::. .:::::::.::::.::: ::.
XP_016 LWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPD
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 KYQLHLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRN
::::::::::::::::: ::.::::::::::::::::::::::::::::::::::::: .
XP_016 KYQLHLHESCVLSLKFAHCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVD
670 680 690 700 710 720
730 740
pF1KE2 NKYIVTGSGDKKATVYEVVY
.:::::::::::::::::.:
XP_016 DKYIVTGSGDKKATVYEVIY
730 740
>>XP_016870569 (OMIM: 605132) PREDICTED: transducin-like (749 aa)
initn: 3166 init1: 2171 opt: 2821 Z-score: 1532.6 bits: 294.3 E(85289): 1.2e-78
Smith-Waterman score: 3227; 65.4% identity (81.8% similar) in 769 aa overlap (1-743:8-749)
10 20 30 40 50
pF1KE2 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEK
:::: :::.: : .:::::.: : :::::::::::::::::::::::::::::
XP_016 MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 TEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQV
:::::::::::::::::::::::::::::::..::::.::::.::.:: :::
XP_016 TEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEQQQ--LQA-------
70 80 90 100 110
120 130 140 150 160
pF1KE2 TVGELNSLIGQQLQPLSH-HAPPVPLTPRPAGLVG------GSATGLLALSGALAAQAQL
: ::: :. ::::::.:.:: ::..::::::.::..:..:
XP_016 -------------QHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHL
120 130 140 150
170 180 190 200 210 220
pF1KE2 AAAVKEDRAGVEAEGSRVERAPSRSASPSPPESL--VEEERPSGPGGG--GKQRADEKEP
.:... . . .: .: .:.: :: :. .:..: :. .. ::...:::
XP_016 P--IKDEKKHHDNDHQR-DRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEI
160 170 180 190 200 210
230 240 250 260 270
pF1KE2 SGPYESDEDKSDYNLVVD--EDQPSEP-PSPATTP-CGKVPICIPARRDLVDSPASLASS
.. :.:: .::: ::::: ...:: : ::: .: . . ..: ::::.:::
XP_016 AARYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASS
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE2 LGSPLPRAKELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVA
..: ..::: ::. ..::.::: .: :: ::: .:. : . .:: :..: .:
XP_016 SSTPSSKSKELSLNE-KSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKP-PGVDPLA
280 290 300 310 320 330
340 350 360 370 380
pF1KE2 --LRSPLTLSSPFTTSFSLGSHSTLNGDLSVP-SSYVSLH-LSPQVSSSVV-------YG
::.:... :. : :.. :. .::.:. : ..:..:: .:::.:.... ::
XP_016 SSLRTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYG
340 350 360 370 380 390
390 400 410 420 430 440
pF1KE2 RSPVMAFESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRH
::::..:. : :.: .. .: .:::::::::::::::::::::::: :::.: :::::
XP_016 RSPVVGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRH
400 410 420 430 440 450
450 460 470 480 490 500
pF1KE2 ARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIR
:::..:: :::::::::::. :.::::::::::::::...:: :.::.::::::::::::
XP_016 ARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIR
460 470 480 490 500 510
510 520 530 540 550 560
pF1KE2 SCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCS
::.::::::.:::::::::::::::::::::::::::::::::::::.:::.::::::::
XP_016 SCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCS
520 530 540 550 560 570
570 580 590 600 610 620
pF1KE2 DGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQH
::::.::::.:::.:::::::::::::::::. ::.::::::::::: ::::::::::::
XP_016 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH
580 590 600 610 620 630
630 640 650 660 670 680
pF1KE2 DFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRWFV
::.:::::::.::. .:::::::.::::.::: ::.::::::::::::::::: ::.:::
XP_016 DFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFV
640 650 660 670 680 690
690 700 710 720 730 740
pF1KE2 STGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY
:::::::::::::::::::::::::::::::::: ..:::::::::::::::::.:
XP_016 STGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY
700 710 720 730 740
>>NP_001269678 (OMIM: 605132) transducin-like enhancer p (748 aa)
initn: 3169 init1: 2171 opt: 2814 Z-score: 1528.9 bits: 293.6 E(85289): 2e-78
Smith-Waterman score: 3218; 65.3% identity (81.7% similar) in 769 aa overlap (1-743:8-748)
10 20 30 40 50
pF1KE2 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEK
:::: :::.: : .:::::.: : :::::::::::::::::::::::::::::
NP_001 MIRDLSKMYPQTRHPAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 TEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQV
:::::::::::::::::::::::::::::::..::::.::::.::.: :::
NP_001 TEMQRHYVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEQQ---LQA-------
70 80 90 100 110
120 130 140 150 160
pF1KE2 TVGELNSLIGQQLQPLSH-HAPPVPLTPRPAGLVG------GSATGLLALSGALAAQAQL
: ::: :. ::::::.:.:: ::..::::::.::..:..:
NP_001 -------------QHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHL
120 130 140 150
170 180 190 200 210 220
pF1KE2 AAAVKEDRAGVEAEGSRVERAPSRSASPSPPESL--VEEERPSGPGGG--GKQRADEKEP
.:... . . .: .: .:.: :: :. .:..: :. .. ::...:::
NP_001 P--IKDEKKHHDNDHQR-DRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEI
160 170 180 190 200 210
230 240 250 260 270
pF1KE2 SGPYESDEDKSDYNLVVD--EDQPSEP-PSPATTP-CGKVPICIPARRDLVDSPASLASS
.. :.:: .::: ::::: ...:: : ::: .: . . ..: ::::.:::
NP_001 AARYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASS
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE2 LGSPLPRAKELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVA
..: ..::: ::. ..::.::: .: :: ::: .:. : . .:: :..: .:
NP_001 SSTPSSKSKELSLNE-KSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKP-PGVDPLA
280 290 300 310 320 330
340 350 360 370 380
pF1KE2 --LRSPLTLSSPFTTSFSLGSHSTLNGDLSVP-SSYVSLH-LSPQVSSSVV-------YG
::.:... :. : :.. :. .::.:. : ..:..:: .:::.:.... ::
NP_001 SSLRTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYG
340 350 360 370 380 390
390 400 410 420 430 440
pF1KE2 RSPVMAFESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRH
::::..:. : :.: .. .: .:::::::::::::::::::::::: :::.: :::::
NP_001 RSPVVGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRH
400 410 420 430 440 450
450 460 470 480 490 500
pF1KE2 ARQLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIR
:::..:: :::::::::::. :.::::::::::::::...:: :.::.::::::::::::
NP_001 ARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIR
460 470 480 490 500 510
510 520 530 540 550 560
pF1KE2 SCKLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCS
::.::::::.:::::::::::::::::::::::::::::::::::::.:::.::::::::
NP_001 SCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCS
520 530 540 550 560 570
570 580 590 600 610 620
pF1KE2 DGNIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQH
::::.::::.:::.:::::::::::::::::. ::.::::::::::: ::::::::::::
NP_001 DGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQH
580 590 600 610 620 630
630 640 650 660 670 680
pF1KE2 DFSSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRWFV
::.:::::::.::. .:::::::.::::.::: ::.::::::::::::::::: ::.:::
NP_001 DFTSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFV
640 650 660 670 680 690
690 700 710 720 730 740
pF1KE2 STGKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY
:::::::::::::::::::::::::::::::::: ..:::::::::::::::::.:
NP_001 STGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY
700 710 720 730 740
>>XP_016870571 (OMIM: 605132) PREDICTED: transducin-like (747 aa)
initn: 3115 init1: 2171 opt: 2770 Z-score: 1505.3 bits: 289.2 E(85289): 4.2e-77
Smith-Waterman score: 3176; 65.0% identity (81.5% similar) in 766 aa overlap (4-743:9-747)
10 20 30 40 50
pF1KE2 MYPQGRHPTPLQSGQPFKFSILEICDRIKEEFQFLQAQYHSLKLECEKLASEKTE
: : .: : .:::::.: : :::::::::::::::::::::::::::::::
XP_016 MARVPPTGQFRFRAPHQPAQPFKFTISESCDRIKEEFQFLQAQYHSLKLECEKLASEKTE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 MQRHYVMYYEMSYGLNIEMHKQAEIVKRLSGICAQIIPFLTQEHQQQVLQAVERAKQVTV
:::::::::::::::::::::::::::::..::::.::::.::.:: :::
XP_016 MQRHYVMYYEMSYGLNIEMHKQAEIVKRLNAICAQVIPFLSQEQQQ--LQA---------
70 80 90 100
120 130 140 150 160
pF1KE2 GELNSLIGQQLQPLSH-HAPPVPLTPRPAGLVG------GSATGLLALSGALAAQAQLAA
: ::: :. ::::::.:.:: ::..::::::.::..:..:
XP_016 -----------QHLSHGHGLPVPLTPHPSGLQPPAIPPIGSSAGLLALSSALGGQSHLP-
110 120 130 140 150
170 180 190 200 210 220
pF1KE2 AVKEDRAGVEAEGSRVERAPSRSASPSPPESL--VEEERPSGPGGG--GKQRADEKEPSG
.:... . . .: .: .:.: :: :. .:..: :. .. ::...::: ..
XP_016 -IKDEKKHHDNDHQR-DRDSIKSSSVSPSASFRGAEKHRNSADYSSESKKQKTEEKEIAA
160 170 180 190 200 210
230 240 250 260 270 280
pF1KE2 PYESDEDKSDYNLVVD--EDQPSEP-PSPATTP-CGKVPICIPARRDLVDSPASLASSLG
:.:: .::: ::::: ...:: : ::: .: . . ..: ::::.::: .
XP_016 RYDSDGEKSDDNLVVDVSNEDPSSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSSS
220 230 240 250 260 270
290 300 310 320 330
pF1KE2 SPLPRAKELILNDLPASTPASKSCDSSPPQDASTPGPSSASHLCQLAAKPAPSTDSVA--
.: ..::: ::. ..::.::: .: :: ::: .:. : . .:: :..: .:
XP_016 TPSSKSKELSLNE-KSTTPVSKSNTPTPRTDAPTPGSNSTPGLRPVPGKP-PGVDPLASS
280 290 300 310 320 330
340 350 360 370 380
pF1KE2 LRSPLTLSSPFTTSFSLGSHSTLNGDLSVP-SSYVSLH-LSPQVSSSVV-------YGRS
::.:... :. : :.. :. .::.:. : ..:..:: .:::.:.... ::::
XP_016 LRTPMAVPCPYPTPFGIVPHAGMNGELTSPGAAYAGLHNISPQMSAAAAAAAAAAAYGRS
340 350 360 370 380 390
390 400 410 420 430 440
pF1KE2 PVMAFESHPHLRGSSVSSSLPSIPGGKPAYSFHVSADGQMQPVPFPSDALVGAGIPRHAR
::..:. : :.: .. .: .:::::::::::::::::::::::: :::.: :::::::
XP_016 PVVGFDPHHHMRVPAIPPNLTGIPGGKPAYSFHVSADGQMQPVPFPPDALIGPGIPRHAR
400 410 420 430 440 450
450 460 470 480 490 500
pF1KE2 QLHTLAHGEVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVAQLDCLNRDNYIRSC
:..:: :::::::::::. :.::::::::::::::...:: :.::.::::::::::::::
XP_016 QINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSC
460 470 480 490 500 510
510 520 530 540 550 560
pF1KE2 KLLPDGRSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDG
.::::::.:::::::::::::::::::::::::::::::::::::.:::.::::::::::
XP_016 RLLPDGRTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDG
520 530 540 550 560 570
570 580 590 600 610 620
pF1KE2 NIVVWDLQNQTMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQHDF
::.::::.:::.:::::::::::::::::. ::.::::::::::: ::::::::::::::
XP_016 NIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQQHDF
580 590 600 610 620 630
630 640 650 660 670 680
pF1KE2 SSQIFSLGHCPNQDWLAVGMESSNVEILHVRKPEKYQLHLHESCVLSLKFASCGRWFVST
.:::::::.::. .:::::::.::::.::: ::.::::::::::::::::: ::.:::::
XP_016 TSQIFSLGYCPTGEWLAVGMENSNVEVLHVTKPDKYQLHLHESCVLSLKFAHCGKWFVST
640 650 660 670 680 690
690 700 710 720 730 740
pF1KE2 GKDNLLNAWRTPYGASIFQSKESSSVLSCDISRNNKYIVTGSGDKKATVYEVVY
:::::::::::::::::::::::::::::::: ..:::::::::::::::::.:
XP_016 GKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY
700 710 720 730 740
743 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:27:35 2016 done: Tue Nov 8 16:27:37 2016
Total Scan time: 11.400 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]