Result of FASTA (omim) for
pF1KE2564
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2564, 608 aa
1>>>pF1KE2564 608 - 608 aa - 608 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3042+/-0.000397; mu= 19.1689+/- 0.025
mean_var=73.1730+/-14.573, 0's: 0 Z-trim(113.8): 99 B-trim: 882 in 2/52
Lambda= 0.149934
statistics sampled from 23239 (23343) to 23239 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.274), width: 16
Scan time: 6.510
The best scores are: opt bits E(85289)
NP_001276093 (OMIM: 607163) lysyl oxidase homolog ( 608) 4367 954.3 0
XP_011531436 (OMIM: 607163) PREDICTED: lysyl oxida ( 753) 3216 705.4 1.7e-202
NP_115992 (OMIM: 607163) lysyl oxidase homolog 3 i ( 753) 3216 705.4 1.7e-202
XP_016860601 (OMIM: 607163) PREDICTED: lysyl oxida ( 392) 2820 619.6 6.4e-177
NP_001276094 (OMIM: 607163) lysyl oxidase homolog ( 392) 2820 619.6 6.4e-177
NP_002309 (OMIM: 606663) lysyl oxidase homolog 2 p ( 774) 2181 481.5 4.4e-135
XP_005270273 (OMIM: 607318) PREDICTED: lysyl oxida ( 757) 2122 468.8 3e-131
XP_006718083 (OMIM: 607318) PREDICTED: lysyl oxida ( 757) 2122 468.8 3e-131
NP_115587 (OMIM: 607318) lysyl oxidase homolog 4 p ( 756) 2121 468.6 3.5e-131
NP_060049 (OMIM: 601969) deleted in malignant brai (2403) 904 205.6 1.5e-51
XP_011537693 (OMIM: 601969) PREDICTED: deleted in (2532) 904 205.7 1.6e-51
NP_002308 (OMIM: 153455,617168) protein-lysine 6-o ( 417) 775 177.2 9.7e-44
XP_016877668 (OMIM: 153456,177650) PREDICTED: lysy ( 225) 759 173.6 6.5e-43
NP_005567 (OMIM: 153456,177650) lysyl oxidase homo ( 574) 758 173.6 1.6e-42
NP_001171573 (OMIM: 153455,617168) protein-lysine ( 187) 744 170.3 5.3e-42
NP_001284579 (OMIM: 606079) scavenger receptor cys (1463) 706 162.7 8.2e-39
XP_005263375 (OMIM: 249500,606709) PREDICTED: neur ( 555) 699 160.9 1.1e-38
XP_011530689 (OMIM: 249500,606709) PREDICTED: neur ( 573) 699 160.9 1.1e-38
NP_003610 (OMIM: 249500,606709) neurotrypsin precu ( 875) 699 161.0 1.5e-38
XP_011537717 (OMIM: 601969) PREDICTED: deleted in (1766) 583 136.1 9.7e-31
XP_011537715 (OMIM: 601969) PREDICTED: deleted in (2282) 583 136.2 1.2e-30
XP_011537713 (OMIM: 601969) PREDICTED: deleted in (2403) 583 136.2 1.2e-30
XP_011537709 (OMIM: 601969) PREDICTED: deleted in (2411) 583 136.2 1.2e-30
XP_011537712 (OMIM: 601969) PREDICTED: deleted in (2411) 583 136.2 1.2e-30
XP_011537711 (OMIM: 601969) PREDICTED: deleted in (2411) 583 136.2 1.2e-30
NP_001307573 (OMIM: 601969) deleted in malignant b (2412) 583 136.2 1.2e-30
XP_011537707 (OMIM: 601969) PREDICTED: deleted in (2413) 583 136.2 1.2e-30
XP_011537705 (OMIM: 601969) PREDICTED: deleted in (2413) 583 136.2 1.2e-30
XP_011537703 (OMIM: 601969) PREDICTED: deleted in (2413) 583 136.2 1.2e-30
NP_015568 (OMIM: 601969) deleted in malignant brai (2413) 583 136.2 1.2e-30
XP_011537701 (OMIM: 601969) PREDICTED: deleted in (2510) 583 136.2 1.3e-30
XP_006717728 (OMIM: 601969) PREDICTED: deleted in (2510) 583 136.2 1.3e-30
XP_011537700 (OMIM: 601969) PREDICTED: deleted in (2521) 583 136.2 1.3e-30
XP_011537698 (OMIM: 601969) PREDICTED: deleted in (2526) 583 136.2 1.3e-30
XP_006717723 (OMIM: 601969) PREDICTED: deleted in (2526) 583 136.2 1.3e-30
XP_011537697 (OMIM: 601969) PREDICTED: deleted in (2532) 583 136.2 1.3e-30
XP_011537694 (OMIM: 601969) PREDICTED: deleted in (2532) 583 136.2 1.3e-30
XP_011537696 (OMIM: 601969) PREDICTED: deleted in (2532) 583 136.2 1.3e-30
XP_011537692 (OMIM: 601969) PREDICTED: deleted in (2532) 583 136.2 1.3e-30
XP_011537695 (OMIM: 601969) PREDICTED: deleted in (2532) 583 136.2 1.3e-30
XP_011537691 (OMIM: 601969) PREDICTED: deleted in (2541) 583 136.2 1.3e-30
XP_011537690 (OMIM: 601969) PREDICTED: deleted in (2542) 583 136.2 1.3e-30
XP_011537704 (OMIM: 601969) PREDICTED: deleted in (2413) 582 136.0 1.4e-30
XP_011537710 (OMIM: 601969) PREDICTED: deleted in (2411) 570 133.4 8.7e-30
NP_001304002 (OMIM: 153455,617168) protein-lysine ( 120) 485 114.1 2.7e-25
NP_981961 (OMIM: 605545) scavenger receptor cystei (1121) 417 100.1 4.3e-20
XP_005253586 (OMIM: 605545) PREDICTED: scavenger r (1124) 417 100.1 4.4e-20
NP_004235 (OMIM: 605545) scavenger receptor cystei (1156) 417 100.1 4.5e-20
XP_016875720 (OMIM: 605545) PREDICTED: scavenger r (1161) 417 100.1 4.5e-20
XP_011518918 (OMIM: 606079) PREDICTED: scavenger r (1421) 403 97.1 4.3e-19
>>NP_001276093 (OMIM: 607163) lysyl oxidase homolog 3 is (608 aa)
initn: 4367 init1: 4367 opt: 4367 Z-score: 5103.1 bits: 954.3 E(85289): 0
Smith-Waterman score: 4367; 100.0% identity (100.0% similar) in 608 aa overlap (1-608:1-608)
10 20 30 40 50 60
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEARVRLKGGAHPGEGRVEVLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEARVRLKGGAHPGEGRVEVLKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 STWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 CGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 RSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 PGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYP
550 560 570 580 590 600
pF1KE2 GQTSNQII
::::::::
NP_001 GQTSNQII
>>XP_011531436 (OMIM: 607163) PREDICTED: lysyl oxidase h (753 aa)
initn: 3304 init1: 3216 opt: 3216 Z-score: 3756.2 bits: 705.4 E(85289): 1.7e-202
Smith-Waterman score: 3310; 82.4% identity (88.2% similar) in 586 aa overlap (42-608:169-753)
20 30 40 50 60
pF1KE2 WGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLA-GFPRKPY---EGRVEIQRAGEWG
.:.: : :. :.: :: ::.. :.
XP_011 DAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWS
140 150 160 170 180 190
70 80 90 100 110 120
pF1KE2 TICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGR----IWLDNLSCSGTEQSVTE
.:: .. . .:..: ::: . ...: : . : . : ...: ::: ..
XP_011 QVCDKGWSAHNSHVVCGMLGFP-SEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSL
200 210 220 230 240 250
130 140 150 160 170
pF1KE2 CASRGWGNSD---CTHDEDAGVICKDQRLPGFSDSNVI--------EARVRLKGGAHPGE
:. . . .: : : : : . . :... ::::::::::::::
XP_011 CSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGE
260 270 280 290 300 310
180 190 200 210 220 230
pF1KE2 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS
320 330 340 350 360 370
240 250 260 270 280 290
pF1KE2 GQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGP
380 390 400 410 420 430
300 310 320 330 340 350
pF1KE2 GPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTEL
440 450 460 470 480 490
360 370 380 390 400 410
pF1KE2 SLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAE
500 510 520 530 540 550
420 430 440 450 460 470
pF1KE2 ENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFT
560 570 580 590 600 610
480 490 500 510 520 530
pF1KE2 HYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQ
620 630 640 650 660 670
540 550 560 570 580 590
pF1KE2 WIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEA
680 690 700 710 720 730
600
pF1KE2 NRRFERYPGQTSNQII
::::::::::::::::
XP_011 NRRFERYPGQTSNQII
740 750
>--
initn: 1173 init1: 1160 opt: 1160 Z-score: 1352.7 bits: 260.7 E(85289): 1.3e-68
Smith-Waterman score: 1160; 97.0% identity (99.4% similar) in 165 aa overlap (1-165:1-165)
10 20 30 40 50 60
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEARVRLKGGAHPGEGRVEVLKA
:::::::::::::::::::::::::::::::::::::::.. .:.
XP_011 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 STWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWK
XP_011 PLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHS
190 200 210 220 230 240
>>NP_115992 (OMIM: 607163) lysyl oxidase homolog 3 isofo (753 aa)
initn: 3304 init1: 3216 opt: 3216 Z-score: 3756.2 bits: 705.4 E(85289): 1.7e-202
Smith-Waterman score: 3310; 82.4% identity (88.2% similar) in 586 aa overlap (42-608:169-753)
20 30 40 50 60
pF1KE2 WGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLA-GFPRKPY---EGRVEIQRAGEWG
.:.: : :. :.: :: ::.. :.
NP_115 DAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWS
140 150 160 170 180 190
70 80 90 100 110 120
pF1KE2 TICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGR----IWLDNLSCSGTEQSVTE
.:: .. . .:..: ::: . ...: : . : . : ...: ::: ..
NP_115 QVCDKGWSAHNSHVVCGMLGFP-SEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSL
200 210 220 230 240 250
130 140 150 160 170
pF1KE2 CASRGWGNSD---CTHDEDAGVICKDQRLPGFSDSNVI--------EARVRLKGGAHPGE
:. . . .: : : : : . . :... ::::::::::::::
NP_115 CSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGE
260 270 280 290 300 310
180 190 200 210 220 230
pF1KE2 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS
320 330 340 350 360 370
240 250 260 270 280 290
pF1KE2 GQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGP
380 390 400 410 420 430
300 310 320 330 340 350
pF1KE2 GPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTEL
440 450 460 470 480 490
360 370 380 390 400 410
pF1KE2 SLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAE
500 510 520 530 540 550
420 430 440 450 460 470
pF1KE2 ENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 ENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFT
560 570 580 590 600 610
480 490 500 510 520 530
pF1KE2 HYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 HYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQ
620 630 640 650 660 670
540 550 560 570 580 590
pF1KE2 WIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 WIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEA
680 690 700 710 720 730
600
pF1KE2 NRRFERYPGQTSNQII
::::::::::::::::
NP_115 NRRFERYPGQTSNQII
740 750
>--
initn: 1173 init1: 1160 opt: 1160 Z-score: 1352.7 bits: 260.7 E(85289): 1.3e-68
Smith-Waterman score: 1160; 97.0% identity (99.4% similar) in 165 aa overlap (1-165:1-165)
10 20 30 40 50 60
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEARVRLKGGAHPGEGRVEVLKA
:::::::::::::::::::::::::::::::::::::::.. .:.
NP_115 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 STWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWK
NP_115 PLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHS
190 200 210 220 230 240
>>XP_016860601 (OMIM: 607163) PREDICTED: lysyl oxidase h (392 aa)
initn: 2820 init1: 2820 opt: 2820 Z-score: 3297.3 bits: 619.6 E(85289): 6.4e-177
Smith-Waterman score: 2820; 100.0% identity (100.0% similar) in 392 aa overlap (217-608:1-392)
190 200 210 220 230 240
pF1KE2 CDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNI
::::::::::::::::::::::::::::::
XP_016 MGQGMGAIHLSEVRCSGQELSLWKCPHKNI
10 20 30
250 260 270 280 290 300
pF1KE2 TAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWG
40 50 60 70 80 90
310 320 330 340 350 360
pF1KE2 TLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITC
100 110 120 130 140 150
370 380 390 400 410 420
pF1KE2 KRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWP
160 170 180 190 200 210
430 440 450 460 470 480
pF1KE2 YGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAE
220 230 240 250 260 270
490 500 510 520 530 540
pF1KE2 GHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYIL
280 290 300 310 320 330
550 560 570 580 590 600
pF1KE2 QVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQ
340 350 360 370 380 390
pF1KE2 II
::
XP_016 II
>>NP_001276094 (OMIM: 607163) lysyl oxidase homolog 3 is (392 aa)
initn: 2820 init1: 2820 opt: 2820 Z-score: 3297.3 bits: 619.6 E(85289): 6.4e-177
Smith-Waterman score: 2820; 100.0% identity (100.0% similar) in 392 aa overlap (217-608:1-392)
190 200 210 220 230 240
pF1KE2 CDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNI
::::::::::::::::::::::::::::::
NP_001 MGQGMGAIHLSEVRCSGQELSLWKCPHKNI
10 20 30
250 260 270 280 290 300
pF1KE2 TAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWG
40 50 60 70 80 90
310 320 330 340 350 360
pF1KE2 TLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITC
100 110 120 130 140 150
370 380 390 400 410 420
pF1KE2 KRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWP
160 170 180 190 200 210
430 440 450 460 470 480
pF1KE2 YGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAE
220 230 240 250 260 270
490 500 510 520 530 540
pF1KE2 GHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYIL
280 290 300 310 320 330
550 560 570 580 590 600
pF1KE2 QVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQ
340 350 360 370 380 390
pF1KE2 II
::
NP_001 II
>>NP_002309 (OMIM: 606663) lysyl oxidase homolog 2 precu (774 aa)
initn: 2677 init1: 1669 opt: 2181 Z-score: 2546.1 bits: 481.5 E(85289): 4.4e-135
Smith-Waterman score: 2290; 55.3% identity (76.7% similar) in 579 aa overlap (51-607:198-771)
30 40 50 60 70
pF1KE2 SSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKP-YEGRVEIQRAGEWGTICDDDFTLQAA
: : .:: ::.... : ::: .: . .
NP_002 FDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNS
170 180 190 200 210 220
80 90 100 110 120 130
pF1KE2 HILCRELGFT-EATGWTHSAKYGPGT--GRIWLDNLSCSGTEQSVTEC------ASRGWG
...: .:: : : :. :. . : : ...:.::: .. : .
NP_002 RVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPMK
230 240 250 260 270 280
140 150 160 170
pF1KE2 NSDCTHDEDAGVICKDQRLPG--FSDSNVIEAR---------VRLKGGAHPGEGRVEVLK
: : . : : : .:: :: .. . : :::.:::. :::::::::
NP_002 NVTCENGLPAVVSC----VPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLK
290 300 310 320 330 340
180 190 200 210 220 230
pF1KE2 ASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLW
. :::::: :::: .:::::::::::::.::..:.:.:::.: :::.:..:.:.: :.
NP_002 NGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSII
350 360 370 380 390 400
240 250 260 270 280 290
pF1KE2 KCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGL
: : .. :.: .::::::: : : . ..::.:::. .:::::: . : : ::.
NP_002 DCKF-NAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGM
410 420 430 440 450 460
300 310 320 330 340 350
pF1KE2 ICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSG-NITEVVMSGVRCTGTELSLDQCA
.::..:: .::::.:::::::.:....:::::: . : ..::::::.:.:::::: .:
NP_002 VCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCR
470 480 490 500 510 520
360 370 380 390 400 410
pF1KE2 HHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLAS
: : ..: . :... ::: ::::: ::.:.. .::.:.:.::::. :: :: :::::..
NP_002 HDGEDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSA
530 540 550 560 570 580
420 430 440 450 460 470
pF1KE2 SARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILT
:: ... :.:::::::::::: :..::::: :::.:.::.:: :::::..:::::.:.
NP_002 SAAQTDPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLN
590 600 610 620 630 640
480 490 500 510 520 530
pF1KE2 PNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITD
::::::::::::::::::::. :..: :::::::.::::.::::.:::::::::.::::
NP_002 LNGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITD
650 660 670 680 690 700
540 550 560 570 580 590
pF1KE2 VKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFER
: ::.:..::::::::::::::..:: ::: .:::::::..::::: .::::....::.
NP_002 VPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEH
710 720 730 740 750 760
600
pF1KE2 YPGQTSNQII
. : .::.
NP_002 FSGLLNNQLSPQ
770
>--
initn: 543 init1: 525 opt: 550 Z-score: 639.4 bits: 128.7 E(85289): 7.1e-29
Smith-Waterman score: 550; 46.2% identity (72.5% similar) in 160 aa overlap (1-158:19-173)
10 20 30 40
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTG-PEKKAGSQG
. :.:. :.. : . .:.: :. :.
NP_002 MERPLCSHLCSCLAMLALLSPLSLAQYDSWPHY-----PEYFQQPAPEYHQPQAPANVAK
10 20 30 40 50
50 60 70 80 90 100
pF1KE2 LRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYG
...:::: :: :::::. :.:::.:::::...:::..:::::..:: .:: :..::
NP_002 IQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 PGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFS-DSNVIEA
: : :::::: :.:.: ... :.: ::: .:: : ::.::.:.:.:.:::. :...:
NP_002 KGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQ
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 RVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQG
NP_002 IENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG
180 190 200 210 220 230
>>XP_005270273 (OMIM: 607318) PREDICTED: lysyl oxidase h (757 aa)
initn: 2775 init1: 1977 opt: 2122 Z-score: 2477.3 bits: 468.8 E(85289): 3e-131
Smith-Waterman score: 2223; 53.8% identity (74.3% similar) in 587 aa overlap (55-607:176-757)
30 40 50 60 70 80
pF1KE2 GSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCR
:: ::.. :.: .::. .:.. ....:
XP_005 SNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCG
150 160 170 180 190 200
90 100 110 120
pF1KE2 ELGF-TEATGWTH------SAKYGPGTGRI---------WLDNLSCSGTEQSVTECA---
::: .:. .: . :. .:. :. ...: ::: ...:
XP_005 MLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQV
210 220 230 240 250 260
130 140 150 160 170
pF1KE2 --SRGWGNSDCTHDEDAGVIC-----------KDQRLPGFSDSNVIEARVRLKGGAHPGE
.:: : : : : : :: ..... : ::::..::. ::
XP_005 APARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEQ---EPRVRLRSGAQVGE
270 280 290 300 310 320
180 190 200 210 220 230
pF1KE2 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS
:::::: ::::::..:.: .::::::.:::::::::: :::.:::.: ::::::::
XP_005 GRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCR
330 340 350 360 370 380
240 250 260 270 280 290
pF1KE2 GQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGP
: : .: :: . . . :.: .::.::::.: : ....::.::: .:: .:::.
XP_005 GYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVN
390 400 410 420 430 440
300 310 320 330 340 350
pF1KE2 GPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGN--ITEVVMSGVRCTGT
: ::: .:...:: ::::::::::::.: :. .:::.: ::. :::::::::.::
XP_005 GVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFW-SGTPRAQEVVMSGVRCSGT
450 460 470 480 490 500
360 370 380 390 400 410
pF1KE2 ELSLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCA
::.:.:: .:: . :.. : :: ::: : ..: ::.... :::::::.::::: .::::
XP_005 ELALQQCQRHGP-VHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCA
510 520 530 540 550 560
420 430 440 450 460 470
pF1KE2 AEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDI
:::::..:: .::::.:::::::.::.::::.:::::.:: :::::.:: ::::...
XP_005 HEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEV
570 580 590 600 610 620
480 490 500 510 520 530
pF1KE2 FTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDID
:::::.:: ::.:::::::::::::::.: ...:: ::::::::.:::::: ::::::
XP_005 FTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDID
630 640 650 660 670 680
540 550 560 570 580 590
pF1KE2 CQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSE
:::.::::: :::::.::..::..:::::::.:: ..: :::::::.:.:::: :...
XP_005 CQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPA
690 700 710 720 730 740
600
pF1KE2 EANRRFERYPGQTSNQII
.:. .:. .: :
XP_005 NAELSLEQEQRLRNNLI
750
>--
initn: 511 init1: 474 opt: 521 Z-score: 605.6 bits: 122.5 E(85289): 5.4e-27
Smith-Waterman score: 521; 49.3% identity (72.4% similar) in 152 aa overlap (9-160:3-148)
10 20 30 40 50 60
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
::: . :. .: ::.: :: :.. :. ..::.: :: :::.:.
XP_005 MAWSPPATLFLFLL--LLGQPPPSR-PQS-LGT--TKLRLVGPESKPEEGRLEV
10 20 30 40
70 80 90 100 110 120
pF1KE2 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
. :.:::.:::.:..: : . ::.::: : :.:::::: : : :::::. : :::.:
XP_005 LHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEARVRLKGGAHPGEGRVEVLKA
. .:.: ::: :::.:.::.::::. .: :. . .: .:
XP_005 LDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 STWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWK
XP_005 KQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKM
170 180 190 200 210 220
>>XP_006718083 (OMIM: 607318) PREDICTED: lysyl oxidase h (757 aa)
initn: 2775 init1: 1977 opt: 2122 Z-score: 2477.3 bits: 468.8 E(85289): 3e-131
Smith-Waterman score: 2223; 53.8% identity (74.3% similar) in 587 aa overlap (55-607:176-757)
30 40 50 60 70 80
pF1KE2 GSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCR
:: ::.. :.: .::. .:.. ....:
XP_006 SNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCG
150 160 170 180 190 200
90 100 110 120
pF1KE2 ELGF-TEATGWTH------SAKYGPGTGRI---------WLDNLSCSGTEQSVTECA---
::: .:. .: . :. .:. :. ...: ::: ...:
XP_006 MLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQV
210 220 230 240 250 260
130 140 150 160 170
pF1KE2 --SRGWGNSDCTHDEDAGVIC-----------KDQRLPGFSDSNVIEARVRLKGGAHPGE
.:: : : : : : :: ..... : ::::..::. ::
XP_006 APARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEQ---EPRVRLRSGAQVGE
270 280 290 300 310 320
180 190 200 210 220 230
pF1KE2 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS
:::::: ::::::..:.: .::::::.:::::::::: :::.:::.: ::::::::
XP_006 GRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCR
330 340 350 360 370 380
240 250 260 270 280 290
pF1KE2 GQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGP
: : .: :: . . . :.: .::.::::.: : ....::.::: .:: .:::.
XP_006 GYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVN
390 400 410 420 430 440
300 310 320 330 340 350
pF1KE2 GPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGN--ITEVVMSGVRCTGT
: ::: .:...:: ::::::::::::.: :. .:::.: ::. :::::::::.::
XP_006 GVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFW-SGTPRAQEVVMSGVRCSGT
450 460 470 480 490 500
360 370 380 390 400 410
pF1KE2 ELSLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCA
::.:.:: .:: . :.. : :: ::: : ..: ::.... :::::::.::::: .::::
XP_006 ELALQQCQRHGP-VHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCA
510 520 530 540 550 560
420 430 440 450 460 470
pF1KE2 AEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDI
:::::..:: .::::.:::::::.::.::::.:::::.:: :::::.:: ::::...
XP_006 HEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEV
570 580 590 600 610 620
480 490 500 510 520 530
pF1KE2 FTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDID
:::::.:: ::.:::::::::::::::.: ...:: ::::::::.:::::: ::::::
XP_006 FTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDID
630 640 650 660 670 680
540 550 560 570 580 590
pF1KE2 CQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSE
:::.::::: :::::.::..::..:::::::.:: ..: :::::::.:.:::: :...
XP_006 CQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPA
690 700 710 720 730 740
600
pF1KE2 EANRRFERYPGQTSNQII
.:. .:. .: :
XP_006 NAELSLEQEQRLRNNLI
750
>--
initn: 511 init1: 474 opt: 521 Z-score: 605.6 bits: 122.5 E(85289): 5.4e-27
Smith-Waterman score: 521; 49.3% identity (72.4% similar) in 152 aa overlap (9-160:3-148)
10 20 30 40 50 60
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
::: . :. .: ::.: :: :.. :. ..::.: :: :::.:.
XP_006 MAWSPPATLFLFLL--LLGQPPPSR-PQS-LGT--TKLRLVGPESKPEEGRLEV
10 20 30 40
70 80 90 100 110 120
pF1KE2 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
. :.:::.:::.:..: : . ::.::: : :.:::::: : : :::::. : :::.:
XP_006 LHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEARVRLKGGAHPGEGRVEVLKA
. .:.: ::: :::.:.::.::::. .: :. . .: .:
XP_006 LDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 STWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWK
XP_006 KQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKM
170 180 190 200 210 220
>>NP_115587 (OMIM: 607318) lysyl oxidase homolog 4 precu (756 aa)
initn: 2775 init1: 1977 opt: 2121 Z-score: 2476.1 bits: 468.6 E(85289): 3.5e-131
Smith-Waterman score: 2226; 54.0% identity (74.3% similar) in 583 aa overlap (55-607:176-756)
30 40 50 60 70 80
pF1KE2 GSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCR
:: ::.. :.: .::. .:.. ....:
NP_115 SNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCG
150 160 170 180 190 200
90 100 110 120
pF1KE2 ELGF-TEATGWTH------SAKYGPGTGRI---------WLDNLSCSGTEQSVTECA---
::: .:. .: . :. .:. :. ...: ::: ...:
NP_115 MLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQV
210 220 230 240 250 260
130 140 150 160 170
pF1KE2 --SRGWGNSDCTHDEDAGVIC-------KDQRLPGFSDSNVIEARVRLKGGAHPGEGRVE
.:: : : : : . : . : . : ::::..::. ::::::
NP_115 APARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVE
270 280 290 300 310 320
180 190 200 210 220 230
pF1KE2 VLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQEL
:: ::::::..:.: .::::::.:::::::::: :::.:::.: :::::::: : :
NP_115 VLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYER
330 340 350 360 370 380
240 250 260 270 280 290
pF1KE2 SLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLR
.: :: . . . :.: .::.::::.: : ....::.::: .:: .:::. : :
NP_115 TLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPR
390 400 410 420 430 440
300 310 320 330 340 350
pF1KE2 WGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGN--ITEVVMSGVRCTGTELSL
:: .:...:: ::::::::::::.: :. .:::.: ::. :::::::::.::::.:
NP_115 WGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFW-SGTPRAQEVVMSGVRCSGTELAL
450 460 470 480 490 500
360 370 380 390 400 410
pF1KE2 DQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEEN
.:: .:: . :.. : :: ::: : ..: ::.... :::::::.::::: .:::: :::
NP_115 QQCQRHGP-VHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEEN
510 520 530 540 550 560
420 430 440 450 460 470
pF1KE2 CLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHY
::..:: .::::.:::::::.::.::::.:::::.:: :::::.:: ::::...::::
NP_115 CLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHY
570 580 590 600 610 620
480 490 500 510 520 530
pF1KE2 DILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWI
:.:: ::.:::::::::::::::.: ...:: ::::::::.:::::: :::::::::.
NP_115 DLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWV
630 640 650 660 670 680
540 550 560 570 580 590
pF1KE2 DITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANR
::::: :::::.::..::..:::::::.:: ..: :::::::.:.:::: :... .:.
NP_115 DITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAEL
690 700 710 720 730 740
600
pF1KE2 RFERYPGQTSNQII
.:. .: :
NP_115 SLEQEQRLRNNLI
750
>--
initn: 511 init1: 474 opt: 521 Z-score: 605.7 bits: 122.5 E(85289): 5.4e-27
Smith-Waterman score: 521; 49.3% identity (72.4% similar) in 152 aa overlap (9-160:3-148)
10 20 30 40 50 60
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
::: . :. .: ::.: :: :.. :. ..::.: :: :::.:.
NP_115 MAWSPPATLFLFLL--LLGQPPPSR-PQS-LGT--TKLRLVGPESKPEEGRLEV
10 20 30 40
70 80 90 100 110 120
pF1KE2 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
. :.:::.:::.:..: : . ::.::: : :.:::::: : : :::::. : :::.:
NP_115 LHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEARVRLKGGAHPGEGRVEVLKA
. .:.: ::: :::.:.::.::::. .: :. . .: .:
NP_115 LDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 STWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWK
NP_115 KQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKM
170 180 190 200 210 220
>>NP_060049 (OMIM: 601969) deleted in malignant brain tu (2403 aa)
initn: 2933 init1: 390 opt: 904 Z-score: 1046.2 bits: 205.6 E(85289): 1.5e-51
Smith-Waterman score: 935; 41.3% identity (65.8% similar) in 380 aa overlap (18-384:331-696)
10 20 30 40
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLG--SPSPSTGPEKKAGSQG----
..::. . .:::.: : ..:.. :
NP_060 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
310 320 330 340 350 360
50 60 70 80 90 100
pF1KE2 LRFRLA-GFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKY
: .::. : : .::::. : :::.:::.. . :...::.:: ::. .:..
NP_060 LALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARF
370 380 390 400 410
110 120 130 140 150
pF1KE2 GPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQ----RLPGFSDSN
: :.: : ::.. ::: :. . : :: . .: :.:::::::.: ::. . ..
NP_060 GQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSDTLPTITLPASTVGS
420 430 440 450 460 470
160 170 180 190 200 210
pF1KE2 VIEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGAR
.:: .:. .:::::: ..:::::: .:: . :.::::.:: : : : ..::
NP_060 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNAR
480 490 500 510 520 530
220 230 240 250 260 270
pF1KE2 MGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSG
.::: : : :..:::::.: ::.:::.. ...:.::.:::: :. : .. :. .:
NP_060 FGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGG
540 550 560 570 580 590
280 290 300 310 320 330
pF1KE2 GRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGN
: : ::::: : :: .: :.: : .: :.::::: :.:. . .. . ....
NP_060 DRCQ--GRVEVLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSG
600 610 620 630 640 650
340 350 360 370 380 390
pF1KE2 ITEVVMSGVRCTGTELSLDQCAHHG--THITCKRTGTRFTAGVICSETASDLLLHSALVQ
.:.. :::.: : : .: ..: .: .: : . :::::: . :
NP_060 --PIVLDDVRCSGHESYLWSCPNNGWLSH-NC---GHHEDAGVICSAAQSRSTPRPDTLS
660 670 680 690 700
400 410 420 430 440 450
pF1KE2 ETAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRH
NP_060 TITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC
710 720 730 740 750 760
>--
initn: 1454 init1: 383 opt: 827 Z-score: 956.2 bits: 189.0 E(85289): 1.6e-46
Smith-Waterman score: 881; 38.9% identity (61.6% similar) in 409 aa overlap (18-384:820-1216)
10 20 30 40
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLG--SPSPSTGPEKKAGSQG----
..:: . .:::.: : ..:.. :
NP_060 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESS
790 800 810 820 830 840
50 60 70 80 90 100
pF1KE2 LRFRLA-GFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKY
: .::. : : .::::. : :::.:::.. . :...::.:: ::. .:..
NP_060 LALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARF
850 860 870 880 890 900
110 120 130 140
pF1KE2 GPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQR------------
: :.: : ::.. ::: :. . : :: . .: :.:::::::. .
NP_060 GQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPT
910 920 930 940 950 960
150 160 170 180 190 200
pF1KE2 --LPGFSDSNVIEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG
::. . .. .:: .:. .:::::: ..:::::: .:: . :.::::.:: :
NP_060 ITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCG
970 980 990 1000 1010 1020
210 220 230 240 250 260
pF1KE2 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL---
: : ..::.::: : : :..:::::.: ::.:::.. ...:.::.:::: :.
NP_060 WAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQS
1030 1040 1050 1060 1070 1080
270 280 290 300
pF1KE2 -----PYT---------GAETRI--RLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGT
: : :.:. . :: .: .. .::::: : :: .: : : :
NP_060 RPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGS----WGTVCDDYWDT
1090 1100 1110 1120 1130 1140
310 320 330 340 350 360
pF1KE2 LEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG--THIT
.: :.::::: :.: . .. . .... .:.. :::.: : : .: :.: .: .
NP_060 NDANVVCRQLGCGWAMSAPGNARFGQGSG--PIVLDDVRCSGHESYLWSCPHNGWLSH-N
1150 1160 1170 1180 1190 1200
370 380 390 400 410 420
pF1KE2 CKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANW
: : . :::::: . :
NP_060 C---GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVL
1210 1220 1230 1240 1250
>--
initn: 988 init1: 382 opt: 650 Z-score: 749.3 bits: 150.7 E(85289): 5.4e-35
Smith-Waterman score: 683; 41.4% identity (65.0% similar) in 266 aa overlap (18-262:1467-1730)
10 20 30 40
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPS--TGPEKKAGSQG----
..::. ..:.:: : : ..:.. :
NP_060 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSEST
1440 1450 1460 1470 1480 1490
50 60 70 80 90 100
pF1KE2 LRFRLA-GFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKY
: .::. : : .::::. : :::.::: . . :...::.:: : . .:..
NP_060 LALRLVNGGDRC--RGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF
1500 1510 1520 1530 1540 1550
110 120 130 140
pF1KE2 GPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQR------------
: :.: : ::.. ::: :. . : :: . .: : :::::::. .
NP_060 GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLT
1560 1570 1580 1590 1600 1610
150 160 170 180 190 200
pF1KE2 --LPGFSDSNVIEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG
::... .. .:: .:. .:::::: ..:::::: .:: . :.::::.:: :
NP_060 TNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG
1620 1630 1640 1650 1660 1670
210 220 230 240 250 260
pF1KE2 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT
: : ..::.::: : : :..:::::.: ::.::::. ...:.: .:::: :.
NP_060 WAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQI
1680 1690 1700 1710 1720 1730
270 280 290 300 310 320
pF1KE2 GAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGL
NP_060 NSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRI
1740 1750 1760 1770 1780 1790
>--
initn: 792 init1: 374 opt: 506 Z-score: 581.0 bits: 119.6 E(85289): 1.3e-25
Smith-Waterman score: 666; 43.2% identity (66.0% similar) in 250 aa overlap (26-258:1219-1466)
10 20 30 40 50
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQG----LRFRLA-GFP
.:::.: : ..:.. : : .::. :
NP_060 WSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGD
1190 1200 1210 1220 1230 1240
60 70 80 90 100 110
pF1KE2 RKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLD
: .::::. : :::.::: . . :...::.:: ::. .:..: :.: : ::
NP_060 RC--QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD
1250 1260 1270 1280 1290 1300
120 130 140 150 160
pF1KE2 NLSCSGTEQSVTECASRGWGNSDCTHDEDAGVIC---KDQRLPG---FSDSNVIEA----
.. ::: :. . : :: . .: : ::::::: ..: :. . :.. :
NP_060 DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSES
1310 1320 1330 1340 1350 1360
170 180 190 200 210
pF1KE2 --RVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMG
.:: .:. .:::::: ..:::::: :: . :.::::.:: : : : ..::.:
NP_060 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFG
1370 1380 1390 1400 1410 1420
220 230 240 250 260 270
pF1KE2 QGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGR
:: : : :..:::::.: ::.:::.. ...:.: .:::
NP_060 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTS
1430 1440 1450 1460 1470 1480
280 290 300 310 320 330
pF1KE2 SQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNIT
NP_060 RASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAM
1490 1500 1510 1520 1530 1540
>--
initn: 759 init1: 364 opt: 396 Z-score: 452.4 bits: 95.8 E(85289): 1.9e-18
Smith-Waterman score: 632; 41.5% identity (62.1% similar) in 277 aa overlap (5-258:59-330)
10 20 30
pF1KE2 MRPVSVWQWSPWGLLLCLLCSSCLGS--PSPSTG
.: . :: .: : . :: :: ::
NP_060 DYASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTL
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE2 PEKKA-GSQ-GLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTE
: ::. :: .::.. . .::::: : :::.:::.. . :...::.::
NP_060 ESTVAEGSDSGLALRLVNGDGR-CQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLG---
90 100 110 120 130 140
100 110 120 130 140
pF1KE2 ATGWTHSAK----YGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVIC--
::. :: .: :.: : ::.. ::: :. . : :: . .: : :::::::
NP_060 -CGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSA
150 160 170 180 190 200
150 160 170 180 190
pF1KE2 -KDQ----------RL--PGFSDSNVIEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKW
. : :. : .... .:: .:. .:::::: ..:::::: :
NP_060 AQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYW
210 220 230 240 250 260
200 210 220 230 240 250
pF1KE2 DLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDC
: . :.::::.:: : : : ..:..::: : : :..:::::.: ::.:::.. ...:
NP_060 DTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNC
270 280 290 300 310 320
260 270 280 290 300 310
pF1KE2 SHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAM
.::.:::
NP_060 GHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGS
330 340 350 360 370 380
>--
initn: 363 init1: 363 opt: 363 Z-score: 413.8 bits: 88.6 E(85289): 2.6e-16
Smith-Waterman score: 363; 52.6% identity (77.3% similar) in 97 aa overlap (162-258:723-819)
140 150 160 170 180 190
pF1KE2 SDCTHDEDAGVICKDQRLPGFSDSNVIEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKW
.:: .:. .:::::: ..:::::: .:
NP_060 AAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSW
700 710 720 730 740 750
200 210 220 230 240 250
pF1KE2 DLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDC
: . :.::::.:: : : : ..::.::: : : :..:::::.: ::.:::.. ...:
NP_060 DTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC
760 770 780 790 800 810
260 270 280 290 300 310
pF1KE2 SHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAM
.: .:::
NP_060 GHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGS
820 830 840 850 860 870
>--
initn: 372 init1: 353 opt: 353 Z-score: 402.1 bits: 86.5 E(85289): 1.2e-15
Smith-Waterman score: 353; 48.9% identity (79.8% similar) in 94 aa overlap (56-149:1887-1980)
30 40 50 60 70 80
pF1KE2 SPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRE
::::: ..: :::.:::..:.: :...::.
NP_060 NTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQ
1860 1870 1880 1890 1900 1910
90 100 110 120 130 140
pF1KE2 LGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICK
:: .:.. .: .: :.: : ::.. :::::... .: .::: . .:.: :::::::.
NP_060 LGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS
1920 1930 1940 1950 1960 1970
150 160 170 180 190 200
pF1KE2 DQRLPGFSDSNVIEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGF
..:
NP_060 GNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRV
1980 1990 2000 2010 2020 2030
608 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:01:53 2016 done: Tue Nov 8 11:01:54 2016
Total Scan time: 6.510 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]