Result of FASTA (ccds) for
pF1KE2525
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2525, 522 aa
1>>>pF1KE2525 522 - 522 aa - 522 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0054+/-0.000779; mu= 15.7564+/- 0.047
mean_var=84.4686+/-16.817, 0's: 0 Z-trim(109.1): 24 B-trim: 0 in 0/53
Lambda= 0.139549
statistics sampled from 10645 (10668) to 10645 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.328), width: 16
Scan time: 2.430
The best scores are: opt bits E(32554)
CCDS34877.1 GSR gene_id:2936|Hs108|chr8 ( 522) 3440 702.3 3.4e-202
CCDS56532.1 GSR gene_id:2936|Hs108|chr8 ( 469) 1949 402.1 7.1e-112
CCDS56530.1 GSR gene_id:2936|Hs108|chr8 ( 440) 1783 368.7 7.7e-102
CCDS56531.1 GSR gene_id:2936|Hs108|chr8 ( 493) 1774 366.9 3e-101
CCDS42981.1 TXNRD2 gene_id:10587|Hs108|chr22 ( 524) 962 203.4 5.1e-52
CCDS58274.1 TXNRD1 gene_id:7296|Hs108|chr12 ( 461) 841 179.0 9.9e-45
CCDS53823.1 TXNRD1 gene_id:7296|Hs108|chr12 ( 499) 841 179.1 1.1e-44
CCDS53821.1 TXNRD1 gene_id:7296|Hs108|chr12 ( 551) 841 179.1 1.1e-44
CCDS53820.1 TXNRD1 gene_id:7296|Hs108|chr12 ( 649) 841 179.1 1.3e-44
CCDS77811.1 TXNRD3 gene_id:114112|Hs108|chr3 ( 643) 812 173.3 7.5e-43
CCDS5749.1 DLD gene_id:1738|Hs108|chr7 ( 509) 648 140.2 5.4e-33
CCDS77810.1 TXNRD3 gene_id:114112|Hs108|chr3 ( 607) 529 116.3 1e-25
CCDS78269.1 DLD gene_id:1738|Hs108|chr7 ( 486) 487 107.8 2.9e-23
CCDS78268.1 DLD gene_id:1738|Hs108|chr7 ( 461) 452 100.7 3.7e-21
CCDS63402.1 TXNRD2 gene_id:10587|Hs108|chr22 ( 338) 444 99.0 8.8e-21
>>CCDS34877.1 GSR gene_id:2936|Hs108|chr8 (522 aa)
initn: 3440 init1: 3440 opt: 3440 Z-score: 3743.6 bits: 702.3 E(32554): 3.4e-202
Smith-Waterman score: 3440; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KE2 MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ
430 440 450 460 470 480
490 500 510 520
pF1KE2 GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
::::::::::::::::::::::::::::::::::::::::::
CCDS34 GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
490 500 510 520
>>CCDS56532.1 GSR gene_id:2936|Hs108|chr8 (469 aa)
initn: 3084 init1: 1949 opt: 1949 Z-score: 2122.0 bits: 402.1 E(32554): 7.1e-112
Smith-Waterman score: 2982; 89.8% identity (89.8% similar) in 522 aa overlap (1-522:1-469)
10 20 30 40 50 60
pF1KE2 MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQ------
250 260 270 280 290
310 320 330 340 350 360
pF1KE2 TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD
:::::::::::::
CCDS56 -----------------------------------------------GIQTDDKGHIIVD
300
370 380 390 400 410 420
pF1KE2 EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE2 IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ
370 380 390 400 410 420
490 500 510 520
pF1KE2 GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
::::::::::::::::::::::::::::::::::::::::::
CCDS56 GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
430 440 450 460
>>CCDS56530.1 GSR gene_id:2936|Hs108|chr8 (440 aa)
initn: 1858 init1: 1770 opt: 1783 Z-score: 1941.8 bits: 368.7 E(32554): 7.7e-102
Smith-Waterman score: 2744; 84.3% identity (84.3% similar) in 522 aa overlap (1-522:1-440)
10 20 30 40 50 60
pF1KE2 MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKK
:::::::::::::::::::::::::
CCDS56 YIAVEMAGILSALGSKTSLMIRHDK-----------------------------------
250 260
310 320 330 340 350 360
pF1KE2 TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD
:::::::::::::
CCDS56 -----------------------------------------------GIQTDDKGHIIVD
270
370 380 390 400 410 420
pF1KE2 EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE2 IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ
340 350 360 370 380 390
490 500 510 520
pF1KE2 GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
::::::::::::::::::::::::::::::::::::::::::
CCDS56 GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
400 410 420 430 440
>>CCDS56531.1 GSR gene_id:2936|Hs108|chr8 (493 aa)
initn: 1808 init1: 1774 opt: 1774 Z-score: 1931.3 bits: 366.9 E(32554): 3e-101
Smith-Waterman score: 3192; 94.4% identity (94.4% similar) in 522 aa overlap (1-522:1-493)
10 20 30 40 50 60
pF1KE2 MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MALLPRALSAGAGPSWRRAARAFRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AVASYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKK
:::::::::::::::::::::::::: :::::
CCDS56 YIAVEMAGILSALGSKTSLMIRHDKV-----------------------------KEVKK
250 260 270
310 320 330 340 350 360
pF1KE2 TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVD
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE2 EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPP
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE2 IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQ
400 410 420 430 440 450
490 500 510 520
pF1KE2 GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
::::::::::::::::::::::::::::::::::::::::::
CCDS56 GLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
460 470 480 490
>>CCDS42981.1 TXNRD2 gene_id:10587|Hs108|chr22 (524 aa)
initn: 629 init1: 190 opt: 962 Z-score: 1047.4 bits: 203.4 E(32554): 5.1e-52
Smith-Waterman score: 1068; 39.9% identity (68.8% similar) in 484 aa overlap (58-522:33-508)
30 40 50 60 70 80
pF1KE2 LLLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELG
::.. .:: ::.:::::::: :..::.::
CCDS42 AMAVALRGLGGRFRWRTQAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQLG
10 20 30 40 50 60
90 100 110 120 130
pF1KE2 ARAAVVESHK---------LGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEG-K
..:::. . ::::::::::.:::.: ..:. . ...: .::. .
CCDS42 RKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVP
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 FNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKK---YTAP
.:: . : . .:. :: .. .: ... . .:.:... ..: : .:
CCDS42 HDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSAD
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 HILIATGGMPSTPHESQIPGA-SLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSAL
::.::::: : : ..: :: ::::: .: :.: ::....:::.:.:.: ::.:...
CCDS42 HIIIATGGRPRYP--THIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGI
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE2 GSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSG-LEVSMVTA
: :..:.: . ::.::...:. :.. . :.. :. ..:.. .: :.:. .
CCDS42 GLDTTIMMR-SIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDS
250 260 270 280 290
320 330 340 350 360 370
pF1KE2 VPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTD-DKGHIIVDEFQNTNVKGIY
. :. . :. : .::::::::.:..:.:.: :..:. : .:.:: . :.: ::
CCDS42 TTGKEDTGTF----DTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIY
300 310 320 330 340 350
380 390 400 410 420 430
pF1KE2 AVGDVC-GKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDE
:.::: :. :::.:: ::: :..::: . : .::.:.::.::. : :::.:.:
CCDS42 AIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDL-MDYDNVPTTVFTPLEYGCVGLSEEE
360 370 380 390 400 410
440 450 460 470 480
pF1KE2 AIHKYGIENVKTYSTSFTPMYHAVTKRK-TKCVMKMVCANKEEKVV-GIHMQGLGCDEML
:. ..: :.:..: . . :. .:. : ..: .:::: . ..: :.:. : . :.
CCDS42 AVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVT
420 430 440 450 460 470
490 500 510 520
pF1KE2 QGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
::::...: ::. :. ::.:::: :::.: ::
CCDS42 QGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCCG
480 490 500 510 520
>>CCDS58274.1 TXNRD1 gene_id:7296|Hs108|chr12 (461 aa)
initn: 468 init1: 202 opt: 841 Z-score: 916.5 bits: 179.0 E(32554): 9.9e-45
Smith-Waterman score: 842; 35.7% identity (67.6% similar) in 442 aa overlap (98-521:17-444)
70 80 90 100 110 120
pF1KE2 LVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHA
::::::::::.:::.: ..:. .. ..:
CCDS58 MVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSR
10 20 30 40
130 140 150 160 170 180
pF1KE2 DYGFPSCEG-KFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPK-PTIE
.::. : : .: . : . ... :: :. : .... ... : . . . .
CCDS58 NYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATN
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE2 VSGKK--YTAPHILIATGGMPSTPHESQIPGAS-LGITSDGFFQLEELPGRSVIVGAGYI
.::. :.: ..::::: :. ::: . :.:: .:.: ::....:::.:.
CCDS58 NKGKEKIYSAERFLIATG---ERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYV
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE2 AVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLK-FSQVKEVKKT
:.: ::.:...: ...:.: . .::.::. .... :..:. :.. .. : .: :..
CCDS58 ALECAGFLAGIGLDVTVMVR-SILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIK-VEQI
170 180 190 200 210 220
310 320 330 340 350
pF1KE2 LSGLEVSMVTAVPGRLPVMTMIPD--------VDCLLWAIGRVPNTKDLSLNKLGIQTDD
.: .:::: :... . . .. :::: :. ..:. .:.. ..
CCDS58 EAG--------TPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINE
230 240 250 260 270
360 370 380 390 400 410
pF1KE2 K-GHIIVDEFQNTNVKGIYAVGDVC-GKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNI
: :.: : . ..::: :::.::. :. :::::: ::: ::.::. . : ::.:.
CCDS58 KTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGST-VKCDYENV
280 290 300 310 320 330
420 430 440 450 460 470
pF1KE2 PTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKR-KTKCVMKMVCANK
::.::. :. ::.:..:..:.: ::...: . : :. .. .: ..:: :..: .:
CCDS58 PTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTK
340 350 360 370 380 390
480 490 500 510 520
pF1KE2 E-EKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
. :.:::.:. : . :. ::::.:.: : :: ..:.:..:::. .: ..::
CCDS58 DNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGA
400 410 420 430 440 450
CCDS58 SILQAGCCG
460
>>CCDS53823.1 TXNRD1 gene_id:7296|Hs108|chr12 (499 aa)
initn: 572 init1: 202 opt: 841 Z-score: 916.0 bits: 179.1 E(32554): 1.1e-44
Smith-Waterman score: 926; 36.0% identity (67.1% similar) in 484 aa overlap (65-521:13-482)
40 50 60 70 80 90
pF1KE2 ALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVE
:: ..:::::::::.:..::. : .. :..
CCDS53 MNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLD
10 20 30 40
100 110 120 130 140
pF1KE2 ---------SHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEG-KFNWRVIK
::::::::::.:::.: ..:. .. ..: .::. : : .: .
CCDS53 FVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMI
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE2 EKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPK-PTIEVSGKK--YTAPHILIATG
: . ... :: :. : .... ... : . . . . .::. :.: ..:::::
CCDS53 EAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATG
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE2 GMPSTPHESQIPGAS-LGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLM
:. ::: . :.:: .:.: ::....:::.:.:.: ::.:...: ...:
CCDS53 ---ERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVM
170 180 190 200 210
270 280 290 300 310
pF1KE2 IRHDKVLRSFDSMISTNCTEELENAGVEVLK-FSQVKEVKKTLSGLEVSMVTAVPGRLPV
.: . .::.::. .... :..:. :.. .. : .: :.. .: .:::: :
CCDS53 VR-SILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIK-VEQIEAG--------TPGRLRV
220 230 240 250 260
320 330 340 350 360 370
pF1KE2 MTMIPD--------VDCLLWAIGRVPNTKDLSLNKLGIQTDDK-GHIIVDEFQNTNVKGI
... . . .. :::: :. ..:. .:.. ..: :.: : . ..::: :
CCDS53 VAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYI
270 280 290 300 310 320
380 390 400 410 420
pF1KE2 YAVGDVC-GKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTED
::.::. :. :::::: ::: ::.::. . : ::.:.::.::. :. ::.:.
CCDS53 YAIGDILEDKVELTPVAIQAGRLLAQRLYAGST-VKCDYENVPTTVFTPLEYGACGLSEE
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE2 EAIHKYGIENVKTYSTSFTPMYHAVTKR-KTKCVMKMVCANKE-EKVVGIHMQGLGCDEM
.:..:.: ::...: . : :. .. .: ..:: :..: .:. :.:::.:. : . :.
CCDS53 KAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEV
390 400 410 420 430 440
490 500 510 520
pF1KE2 LQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
::::.:.: : :: ..:.:..:::. .: ..::
CCDS53 TQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGCCG
450 460 470 480 490
>>CCDS53821.1 TXNRD1 gene_id:7296|Hs108|chr12 (551 aa)
initn: 572 init1: 202 opt: 841 Z-score: 915.4 bits: 179.1 E(32554): 1.1e-44
Smith-Waterman score: 926; 36.0% identity (67.1% similar) in 484 aa overlap (65-521:65-534)
40 50 60 70 80 90
pF1KE2 ALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVE
:: ..:::::::::.:..::. : .. :..
CCDS53 HGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLD
40 50 60 70 80 90
100 110 120 130 140
pF1KE2 ---------SHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEG-KFNWRVIK
::::::::::.:::.: ..:. .. ..: .::. : : .: .
CCDS53 FVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMI
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE2 EKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPK-PTIEVSGKK--YTAPHILIATG
: . ... :: :. : .... ... : . . . . .::. :.: ..:::::
CCDS53 EAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATG
160 170 180 190 200 210
210 220 230 240 250 260
pF1KE2 GMPSTPHESQIPGAS-LGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLM
:. ::: . :.:: .:.: ::....:::.:.:.: ::.:...: ...:
CCDS53 ---ERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVM
220 230 240 250 260 270
270 280 290 300 310
pF1KE2 IRHDKVLRSFDSMISTNCTEELENAGVEVLK-FSQVKEVKKTLSGLEVSMVTAVPGRLPV
.: . .::.::. .... :..:. :.. .. : .: :.. .: .:::: :
CCDS53 VR-SILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIK-VEQIEAG--------TPGRLRV
280 290 300 310 320
320 330 340 350 360 370
pF1KE2 MTMIPD--------VDCLLWAIGRVPNTKDLSLNKLGIQTDDK-GHIIVDEFQNTNVKGI
... . . .. :::: :. ..:. .:.. ..: :.: : . ..::: :
CCDS53 VAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYI
330 340 350 360 370 380
380 390 400 410 420
pF1KE2 YAVGDVC-GKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTED
::.::. :. :::::: ::: ::.::. . : ::.:.::.::. :. ::.:.
CCDS53 YAIGDILEDKVELTPVAIQAGRLLAQRLYAGST-VKCDYENVPTTVFTPLEYGACGLSEE
390 400 410 420 430 440
430 440 450 460 470 480
pF1KE2 EAIHKYGIENVKTYSTSFTPMYHAVTKR-KTKCVMKMVCANKE-EKVVGIHMQGLGCDEM
.:..:.: ::...: . : :. .. .: ..:: :..: .:. :.:::.:. : . :.
CCDS53 KAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEV
450 460 470 480 490 500
490 500 510 520
pF1KE2 LQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
::::.:.: : :: ..:.:..:::. .: ..::
CCDS53 TQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGCCG
510 520 530 540 550
>>CCDS53820.1 TXNRD1 gene_id:7296|Hs108|chr12 (649 aa)
initn: 572 init1: 202 opt: 841 Z-score: 914.3 bits: 179.1 E(32554): 1.3e-44
Smith-Waterman score: 926; 36.0% identity (67.1% similar) in 484 aa overlap (65-521:163-632)
40 50 60 70 80 90
pF1KE2 ALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVE
:: ..:::::::::.:..::. : .. :..
CCDS53 HGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLD
140 150 160 170 180 190
100 110 120 130 140
pF1KE2 ---------SHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEG-KFNWRVIK
::::::::::.:::.: ..:. .. ..: .::. : : .: .
CCDS53 FVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMI
200 210 220 230 240 250
150 160 170 180 190 200
pF1KE2 EKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPK-PTIEVSGKK--YTAPHILIATG
: . ... :: :. : .... ... : . . . . .::. :.: ..:::::
CCDS53 EAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATG
260 270 280 290 300 310
210 220 230 240 250 260
pF1KE2 GMPSTPHESQIPGAS-LGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLM
:. ::: . :.:: .:.: ::....:::.:.:.: ::.:...: ...:
CCDS53 ---ERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVM
320 330 340 350 360
270 280 290 300 310
pF1KE2 IRHDKVLRSFDSMISTNCTEELENAGVEVLK-FSQVKEVKKTLSGLEVSMVTAVPGRLPV
.: . .::.::. .... :..:. :.. .. : .: :.. .: .:::: :
CCDS53 VR-SILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIK-VEQIEAG--------TPGRLRV
370 380 390 400 410
320 330 340 350 360 370
pF1KE2 MTMIPD--------VDCLLWAIGRVPNTKDLSLNKLGIQTDDK-GHIIVDEFQNTNVKGI
... . . .. :::: :. ..:. .:.. ..: :.: : . ..::: :
CCDS53 VAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYI
420 430 440 450 460 470
380 390 400 410 420
pF1KE2 YAVGDVC-GKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTED
::.::. :. :::::: ::: ::.::. . : ::.:.::.::. :. ::.:.
CCDS53 YAIGDILEDKVELTPVAIQAGRLLAQRLYAGST-VKCDYENVPTTVFTPLEYGACGLSEE
480 490 500 510 520 530
430 440 450 460 470 480
pF1KE2 EAIHKYGIENVKTYSTSFTPMYHAVTKR-KTKCVMKMVCANKE-EKVVGIHMQGLGCDEM
.:..:.: ::...: . : :. .. .: ..:: :..: .:. :.:::.:. : . :.
CCDS53 KAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEV
540 550 560 570 580 590
490 500 510 520
pF1KE2 LQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR
::::.:.: : :: ..:.:..:::. .: ..::
CCDS53 TQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGCCG
600 610 620 630 640
>>CCDS77811.1 TXNRD3 gene_id:114112|Hs108|chr3 (643 aa)
initn: 594 init1: 225 opt: 812 Z-score: 882.8 bits: 173.3 E(32554): 7.5e-43
Smith-Waterman score: 896; 36.4% identity (65.9% similar) in 481 aa overlap (65-521:157-626)
40 50 60 70 80 90
pF1KE2 ALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVE
:: ..::::::::. :..:: :: .. :..
CCDS77 KVHVGGCDQTFQAYQSGLLQKLLQEDLAYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLD
130 140 150 160 170 180
100 110 120 130 140
pF1KE2 ---------SHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEG-KFNWRVIK
: ::::::::::.:::.: ..:. .. . : .:. . . ::...
CCDS77 FVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALCDSRKFGWEYNQQVRHNWETMT
190 200 210 220 230 240
150 160 170 180 190
pF1KE2 EKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKK-----YTAPHILIA
. . ..: :: :. .: .. . . ... :. : :....:: ::: ...::
CCDS77 KAIQNHISSLNWGYRLSLREKAVAYVNSYGEFVEHHK--IKATNKKGQETYYTAAQFVIA
250 260 270 280 290 300
200 210 220 230 240 250
pF1KE2 TGGMPSTPHESQIPGAS-LGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTS
:: :. : : . :::: .:.: ::....:::.:.:.: ::.:...: ..
CCDS77 TG---ERPRYLGIQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVT
310 320 330 340 350 360
260 270 280 290 300 310
pF1KE2 LMIRHDKVLRSFDSMISTNCTEELENAGVEVL-KF--SQVKEVKKTLSGLEVSMVTAVPG
.:.: . .::.::. .. . .:. ::. : :: .:....: : .. .. :
CCDS77 VMVR-SILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEG
370 380 390 400 410 420
320 330 340 350 360 370
pF1KE2 RLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDK-GHIIVDEFQNTNVKGIYAVG
. . . .: :::: :. ..:.:.:.. ..: :.: :.. ..::: .::::
CCDS77 TETIEGVY---NTVLLAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVG
430 440 450 460 470
380 390 400 410 420 430
pF1KE2 DVC-GKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIH
:. : :::::: .:. ::.::: . . : :: :.::.::. : ::.:..::.
CCDS77 DILEDKPELTPVAIQSGKLLAQRLFGASLE-KCDYINVPTTVFTPLEYGCCGLSEEKAIE
480 490 500 510 520 530
440 450 460 470 480 490
pF1KE2 KYGIENVKTYSTSFTPMYHAVTKRKTK-CVMKMVCANK--EEKVVGIHMQGLGCDEMLQG
: ::.. : : : :. .:. :... : :..: :: ...:.:.:. : . :. ::
CCDS77 VYKKENLEIYHTLFWPLEWTVAGRENNTCYAKIIC-NKFDHDRVIGFHILGPNAGEVTQG
540 550 560 570 580 590
500 510 520
pF1KE2 FAVAVKMGATKADFDNTVAIHPTSSEELVTLR
::.:.: : :: .:.:..:::: .: ..::
CCDS77 FAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKGCCG
600 610 620 630 640
522 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:31:27 2016 done: Tue Nov 8 03:31:27 2016
Total Scan time: 2.430 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]