Result of FASTA (omim) for
pF1KE2521
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2521, 551 aa
1>>>pF1KE2521 551 - 551 aa - 551 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6079+/-0.000384; mu= -0.2287+/- 0.024
mean_var=231.9121+/-47.899, 0's: 0 Z-trim(120.0): 28 B-trim: 997 in 2/60
Lambda= 0.084219
statistics sampled from 34670 (34698) to 34670 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.407), width: 16
Scan time: 12.230
The best scores are: opt bits E(85289)
NP_060204 (OMIM: 610182) palmdelphin [Homo sapiens ( 551) 3616 452.4 1.7e-126
XP_005259623 (OMIM: 608134) PREDICTED: paralemmin- ( 386) 387 59.9 1.7e-08
NP_002570 (OMIM: 608134) paralemmin-1 isoform 1 [H ( 387) 387 59.9 1.7e-08
XP_005259622 (OMIM: 608134) PREDICTED: paralemmin- ( 389) 387 59.9 1.7e-08
NP_001035224 (OMIM: 608134) paralemmin-1 isoform 2 ( 343) 285 47.5 8.1e-05
XP_016882339 (OMIM: 608134) PREDICTED: paralemmin- ( 345) 285 47.5 8.1e-05
>>NP_060204 (OMIM: 610182) palmdelphin [Homo sapiens] (551 aa)
initn: 3616 init1: 3616 opt: 3616 Z-score: 2391.8 bits: 452.4 E(85289): 1.7e-126
Smith-Waterman score: 3616; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551)
10 20 30 40 50 60
pF1KE2 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 IRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 QQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 LPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDAQTTGDGTEDPSLTALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDAQTTGDGTEDPSLTALR
490 500 510 520 530 540
550
pF1KE2 MRMAKLGKKVI
:::::::::::
NP_060 MRMAKLGKKVI
550
>>XP_005259623 (OMIM: 608134) PREDICTED: paralemmin-1 is (386 aa)
initn: 445 init1: 184 opt: 387 Z-score: 273.7 bits: 59.9 E(85289): 1.7e-08
Smith-Waterman score: 429; 36.5% identity (62.0% similar) in 274 aa overlap (10-278:13-273)
10 20 30 40 50
pF1KE2 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGI-S
:::::..::: : :: .:: ..:... . ::::.:::::.:::.: :
XP_005 MVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 SGKE-QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIER
:..: .:....: :.:... ..::.:. ::::::. ::... .: .: : :
XP_005 SASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAP--SPVR
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 TTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYA
. . .::: : . . . ::. .:. . . . . . . :.:.
XP_005 APAP-----SPAKEERKTEVVMNSQQTPVGTPKD---KRVSNTPLRTVDGSPMMKAAMYS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 MEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLA
.:: :::: :::. :::: : . :::::.: : :.::... : :: :.
XP_005 VEITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGT---AENGIHPLS
180 190 200 210 220
240 250 260 270 280 290
pF1KE2 PVEVEELLRQASE---RNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTN
::.::...:.: .. : . : : :::.:. .:
XP_005 SSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGPP
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 GLGIGVNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWE
XP_005 GIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAA
290 300 310 320 330 340
>>NP_002570 (OMIM: 608134) paralemmin-1 isoform 1 [Homo (387 aa)
initn: 445 init1: 184 opt: 387 Z-score: 273.7 bits: 59.9 E(85289): 1.7e-08
Smith-Waterman score: 429; 36.5% identity (62.0% similar) in 274 aa overlap (10-278:14-274)
10 20 30 40 50
pF1KE2 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGI-
:::::..::: : :: .:: ..:... . ::::.:::::.:::.:
NP_002 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 SSGKE-QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIE
::..: .:....: :.:... ..::.:. ::::::. ::... .: .: :
NP_002 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAP--SPV
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 RTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALY
:. . .::: : . . . ::. .:. . . . . . . :.:
NP_002 RAPAP-----SPAKEERKTEVVMNSQQTPVGTPKD---KRVSNTPLRTVDGSPMMKAAMY
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 AMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGL
..:: :::: :::. :::: : . :::::.: : :.::... : :: :
NP_002 SVEITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGT---AENGIHPL
180 190 200 210 220
240 250 260 270 280 290
pF1KE2 APVEVEELLRQASE---RNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKT
. ::.::...:.: .. : . : : :::.:. .:
NP_002 SSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATSGP
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 NGLGIGVNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPW
NP_002 PGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSA
290 300 310 320 330 340
>>XP_005259622 (OMIM: 608134) PREDICTED: paralemmin-1 is (389 aa)
initn: 445 init1: 184 opt: 387 Z-score: 273.7 bits: 59.9 E(85289): 1.7e-08
Smith-Waterman score: 429; 36.5% identity (62.0% similar) in 274 aa overlap (10-278:16-276)
10 20 30 40 50
pF1KE2 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDG
:::::..::: : :: .:: ..:... . ::::.:::::.:::.:
XP_005 MLPRVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 I-SSGKE-QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKS
::..: .:....: :.:... ..::.:. ::::::. ::... .: .: :
XP_005 TPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAP--S
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 IERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKA
:. . .::: : . . . ::. .:. . . . . . . :
XP_005 PVRAPAP-----SPAKEERKTEVVMNSQQTPVGTPKD---KRVSNTPLRTVDGSPMMKAA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 LYAMEIKVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTD
.:..:: :::: :::. :::: : . :::::.: : :.::... : ::
XP_005 MYSVEITVEKDKVTGETRVLSSTTLLPRQPLPLGIKVYEDETKVVHAVDGT---AENGIH
180 190 200 210 220
240 250 260 270 280
pF1KE2 GLAPVEVEELLRQASE---RNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKI
:. ::.::...:.: .. : . : : :::.:. .:
XP_005 PLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREITGVQAQPGEATS
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE2 KTNGLGIGVNESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMT
XP_005 GPPGIQPGQEPPVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPKEPAPPNG
290 300 310 320 330 340
>>NP_001035224 (OMIM: 608134) paralemmin-1 isoform 2 [Ho (343 aa)
initn: 363 init1: 183 opt: 285 Z-score: 207.5 bits: 47.5 E(85289): 8.1e-05
Smith-Waterman score: 285; 48.5% identity (82.5% similar) in 97 aa overlap (10-104:14-110)
10 20 30 40 50
pF1KE2 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGI-
:::::..::: : :: .:: ..:... . ::::.:::::.:::.:
NP_001 MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 SSGKE-QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIE
::..: .:....: :.:... ..::.:. ::::::. ::... .: .:
NP_001 SSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 RTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALY
NP_001 PAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAENGI
130 140 150 160 170 180
>>XP_016882339 (OMIM: 608134) PREDICTED: paralemmin-1 is (345 aa)
initn: 363 init1: 183 opt: 285 Z-score: 207.4 bits: 47.5 E(85289): 8.1e-05
Smith-Waterman score: 285; 48.5% identity (82.5% similar) in 97 aa overlap (10-104:16-112)
10 20 30 40 50
pF1KE2 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDG
:::::..::: : :: .:: ..:... . ::::.:::::.:::.:
XP_016 MLPRVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 I-SSGKE-QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKS
::..: .:....: :.:... ..::.:. ::::::. ::... .: .:
XP_016 TPSSASEGDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 IERTTEDIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKA
XP_016 RAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAVVHAVDGTAEN
130 140 150 160 170 180
551 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:20:11 2016 done: Tue Nov 8 03:20:13 2016
Total Scan time: 12.230 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]