Result of FASTA (omim) for
pF1KE2466
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2466, 986 aa
1>>>pF1KE2466 986 - 986 aa - 986 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4011+/-0.000438; mu= 21.6492+/- 0.027
mean_var=73.7470+/-14.778, 0's: 0 Z-trim(110.8): 85 B-trim: 334 in 1/53
Lambda= 0.149349
statistics sampled from 19146 (19231) to 19146 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.225), width: 16
Scan time: 12.230
The best scores are: opt bits E(85289)
NP_060513 (OMIM: 610108) anoctamin-1 [Homo sapiens ( 986) 6642 1441.3 0
XP_016873445 (OMIM: 610108) PREDICTED: anoctamin-1 ( 985) 6624 1437.4 0
XP_016873446 (OMIM: 610108) PREDICTED: anoctamin-1 ( 982) 6602 1432.7 0
XP_011543427 (OMIM: 610108) PREDICTED: anoctamin-1 ( 982) 4936 1073.7 0
XP_011543428 (OMIM: 610108) PREDICTED: anoctamin-1 ( 978) 4924 1071.1 0
XP_006718667 (OMIM: 610108) PREDICTED: anoctamin-1 ( 892) 4862 1057.7 0
XP_011543431 (OMIM: 610108) PREDICTED: anoctamin-1 ( 979) 4862 1057.8 0
XP_006718665 (OMIM: 610108) PREDICTED: anoctamin-1 ( 980) 4862 1057.8 0
XP_011543423 (OMIM: 610108) PREDICTED: anoctamin-1 (1008) 4862 1057.8 0
XP_011543425 (OMIM: 610108) PREDICTED: anoctamin-1 (1007) 4844 1053.9 0
XP_011543426 (OMIM: 610108) PREDICTED: anoctamin-1 (1004) 4822 1049.2 0
XP_011543429 (OMIM: 610108) PREDICTED: anoctamin-1 ( 960) 3238 707.9 6.6e-203
XP_006718668 (OMIM: 610108) PREDICTED: anoctamin-1 ( 840) 3235 707.2 9.3e-203
XP_011543430 (OMIM: 610108) PREDICTED: anoctamin-1 ( 956) 3235 707.2 1e-202
XP_011543433 (OMIM: 610108) PREDICTED: anoctamin-1 ( 642) 2967 649.4 1.8e-185
NP_001265526 (OMIM: 610109) anoctamin-2 isoform 2 ( 999) 2185 481.0 1.4e-134
NP_001265525 (OMIM: 610109) anoctamin-2 isoform 1 (1003) 2185 481.0 1.4e-134
XP_011519280 (OMIM: 610109) PREDICTED: anoctamin-2 ( 787) 2175 478.8 5e-134
XP_016875161 (OMIM: 610109) PREDICTED: anoctamin-2 ( 921) 1725 381.8 8.8e-105
XP_011519277 (OMIM: 610109) PREDICTED: anoctamin-2 ( 994) 1725 381.9 9.3e-105
XP_006719051 (OMIM: 610109) PREDICTED: anoctamin-2 ( 998) 1725 381.9 9.4e-105
XP_011518584 (OMIM: 610110,615034) PREDICTED: anoc ( 515) 1254 280.2 1.9e-74
XP_016873608 (OMIM: 610110,615034) PREDICTED: anoc ( 738) 1254 280.3 2.6e-74
XP_016873607 (OMIM: 610110,615034) PREDICTED: anoc ( 835) 1254 280.3 2.9e-74
NP_001300656 (OMIM: 610110,615034) anoctamin-3 iso ( 835) 1254 280.3 2.9e-74
NP_113606 (OMIM: 610110,615034) anoctamin-3 isofor ( 981) 1254 280.4 3.3e-74
NP_001300655 (OMIM: 610110,615034) anoctamin-3 iso (1042) 1254 280.4 3.4e-74
XP_011518251 (OMIM: 166260,608662,611307,613319) P ( 882) 1247 278.8 8.5e-74
XP_005252879 (OMIM: 166260,608662,611307,613319) P ( 887) 1247 278.8 8.6e-74
XP_005252878 (OMIM: 166260,608662,611307,613319) P ( 898) 1247 278.8 8.7e-74
XP_005252877 (OMIM: 166260,608662,611307,613319) P ( 899) 1247 278.8 8.7e-74
NP_001136121 (OMIM: 166260,608662,611307,613319) a ( 912) 1247 278.8 8.8e-74
NP_998764 (OMIM: 166260,608662,611307,613319) anoc ( 913) 1247 278.8 8.8e-74
XP_005268764 (OMIM: 262890,608663) PREDICTED: anoc ( 877) 1152 258.4 1.2e-67
NP_001136150 (OMIM: 262890,608663) anoctamin-6 iso ( 892) 1152 258.4 1.3e-67
XP_005268763 (OMIM: 262890,608663) PREDICTED: anoc ( 899) 1152 258.4 1.3e-67
NP_001020527 (OMIM: 262890,608663) anoctamin-6 iso ( 910) 1152 258.4 1.3e-67
NP_001191732 (OMIM: 262890,608663) anoctamin-6 iso ( 931) 1152 258.4 1.3e-67
NP_001136151 (OMIM: 262890,608663) anoctamin-6 iso ( 929) 1087 244.4 2.1e-63
XP_016874306 (OMIM: 610111) PREDICTED: anoctamin-4 ( 784) 1066 239.8 4.3e-62
XP_016874303 (OMIM: 610111) PREDICTED: anoctamin-4 ( 784) 1066 239.8 4.3e-62
XP_016874305 (OMIM: 610111) PREDICTED: anoctamin-4 ( 784) 1066 239.8 4.3e-62
XP_016874304 (OMIM: 610111) PREDICTED: anoctamin-4 ( 784) 1066 239.8 4.3e-62
XP_016874302 (OMIM: 610111) PREDICTED: anoctamin-4 ( 861) 1066 239.8 4.6e-62
XP_016874301 (OMIM: 610111) PREDICTED: anoctamin-4 ( 896) 1066 239.8 4.8e-62
XP_016874300 (OMIM: 610111) PREDICTED: anoctamin-4 ( 905) 1066 239.8 4.8e-62
XP_016874299 (OMIM: 610111) PREDICTED: anoctamin-4 ( 920) 1066 239.9 4.9e-62
XP_016874297 (OMIM: 610111) PREDICTED: anoctamin-4 ( 920) 1066 239.9 4.9e-62
NP_849148 (OMIM: 610111) anoctamin-4 isoform 2 [Ho ( 920) 1066 239.9 4.9e-62
XP_011536216 (OMIM: 610111) PREDICTED: anoctamin-4 ( 920) 1066 239.9 4.9e-62
>>NP_060513 (OMIM: 610108) anoctamin-1 [Homo sapiens] (986 aa)
initn: 6642 init1: 6642 opt: 6642 Z-score: 7727.4 bits: 1441.3 E(85289): 0
Smith-Waterman score: 6642; 100.0% identity (100.0% similar) in 986 aa overlap (1-986:1-986)
10 20 30 40 50 60
pF1KE2 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 PEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 SDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 VMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPC
910 920 930 940 950 960
970 980
pF1KE2 NHHNTKACPDSLGSPAPSHAYHGGVL
::::::::::::::::::::::::::
NP_060 NHHNTKACPDSLGSPAPSHAYHGGVL
970 980
>>XP_016873445 (OMIM: 610108) PREDICTED: anoctamin-1 iso (985 aa)
initn: 3597 init1: 3597 opt: 6624 Z-score: 7706.5 bits: 1437.4 E(85289): 0
Smith-Waterman score: 6624; 99.9% identity (99.9% similar) in 986 aa overlap (1-986:1-985)
10 20 30 40 50 60
pF1KE2 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHI
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_016 ATFMEHWKRKQMRLNYRWDLTGFEEEE-AVKDHPRAEYEARVLEKSLKKESRNKEKRRHI
430 440 450 460 470
490 500 510 520 530 540
pF1KE2 PEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 SFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE2 CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE2 PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRA
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE2 KDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNV
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE2 SDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNL
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE2 VMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPC
900 910 920 930 940 950
970 980
pF1KE2 NHHNTKACPDSLGSPAPSHAYHGGVL
::::::::::::::::::::::::::
XP_016 NHHNTKACPDSLGSPAPSHAYHGGVL
960 970 980
>>XP_016873446 (OMIM: 610108) PREDICTED: anoctamin-1 iso (982 aa)
initn: 3560 init1: 3560 opt: 6602 Z-score: 7680.9 bits: 1432.7 E(85289): 0
Smith-Waterman score: 6602; 99.6% identity (99.6% similar) in 986 aa overlap (1-986:1-982)
10 20 30 40 50 60
pF1KE2 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHI
::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_016 ATFMEHWKRKQMRLNYRWDLTGFEEEE----DHPRAEYEARVLEKSLKKESRNKEKRRHI
430 440 450 460 470
490 500 510 520 530 540
pF1KE2 PEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEK
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 SFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE2 CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE2 PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRA
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE2 KDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNV
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE2 SDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNL
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE2 VMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPC
900 910 920 930 940 950
970 980
pF1KE2 NHHNTKACPDSLGSPAPSHAYHGGVL
::::::::::::::::::::::::::
XP_016 NHHNTKACPDSLGSPAPSHAYHGGVL
960 970 980
>>XP_011543427 (OMIM: 610108) PREDICTED: anoctamin-1 iso (982 aa)
initn: 5019 init1: 3235 opt: 4936 Z-score: 5740.9 bits: 1073.7 E(85289): 0
Smith-Waterman score: 6354; 95.2% identity (95.2% similar) in 1008 aa overlap (1-986:1-982)
10 20 30 40 50 60
pF1KE2 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
190 200 210 220 230 240
250 260 270
pF1KE2 FDSKTRSTIVYEILKRTTCTKAKYSMG----------------------ITSLLANGVYA
::::::::::::::::::::::::::: :::::::::::
XP_011 FDSKTRSTIVYEILKRTTCTKAKYSMGQGEGRKKDSALLSKRRKCGKYGITSLLANGVYA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE2 AAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVY
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE2 TQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE2 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE2 EARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLT
::::::::::::::::: :::::::::::::::::
XP_011 EARVLEKSLKKESRNKE--------------------------TDKVKLTWRDRFPAYLT
490 500 510
520 530 540 550 560 570
pF1KE2 NLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIIL
520 530 540 550 560 570
580 590 600 610 620 630
pF1KE2 LDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGD
580 590 600 610 620 630
640 650 660 670 680 690
pF1KE2 YVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQ
640 650 660 670 680 690
700 710 720 730 740 750
pF1KE2 SPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNI
700 710 720 730 740 750
760 770 780 790 800 810
pF1KE2 IEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYL
760 770 780 790 800 810
820 830 840 850 860 870
pF1KE2 YMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYD
820 830 840 850 860 870
880 890 900 910 920 930
pF1KE2 ISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREE
880 890 900 910 920 930
940 950 960 970 980
pF1KE2 QDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
940 950 960 970 980
>>XP_011543428 (OMIM: 610108) PREDICTED: anoctamin-1 iso (978 aa)
initn: 5019 init1: 3235 opt: 4924 Z-score: 5726.9 bits: 1071.1 E(85289): 0
Smith-Waterman score: 6314; 94.8% identity (94.8% similar) in 1008 aa overlap (1-986:1-978)
10 20 30 40 50 60
pF1KE2 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
190 200 210 220 230 240
250 260 270
pF1KE2 FDSKTRSTIVYEILKRTTCTKAKYSMG----------------------ITSLLANGVYA
::::::::::::::::::::::::::: :::::::::::
XP_011 FDSKTRSTIVYEILKRTTCTKAKYSMGQGEGRKKDSALLSKRRKCGKYGITSLLANGVYA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE2 AAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVY
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE2 TQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE2 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY
::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_011 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEE----DHPRAEY
430 440 450 460 470
460 470 480 490 500 510
pF1KE2 EARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLT
::::::::::::::::: :::::::::::::::::
XP_011 EARVLEKSLKKESRNKE--------------------------TDKVKLTWRDRFPAYLT
480 490 500 510
520 530 540 550 560 570
pF1KE2 NLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIIL
520 530 540 550 560 570
580 590 600 610 620 630
pF1KE2 LDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGD
580 590 600 610 620 630
640 650 660 670 680 690
pF1KE2 YVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQ
640 650 660 670 680 690
700 710 720 730 740 750
pF1KE2 SPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNI
700 710 720 730 740 750
760 770 780 790 800 810
pF1KE2 IEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYL
760 770 780 790 800 810
820 830 840 850 860 870
pF1KE2 YMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYD
820 830 840 850 860 870
880 890 900 910 920 930
pF1KE2 ISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREE
880 890 900 910 920 930
940 950 960 970 980
pF1KE2 QDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
940 950 960 970
>>XP_006718667 (OMIM: 610108) PREDICTED: anoctamin-1 iso (892 aa)
initn: 4852 init1: 4852 opt: 4862 Z-score: 5655.3 bits: 1057.7 E(85289): 0
Smith-Waterman score: 5798; 97.5% identity (97.5% similar) in 892 aa overlap (117-986:1-892)
90 100 110 120 130 140
pF1KE2 DTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDE
::::::::::::::::::::::::::::::
XP_006 MDYHEDDKRFRREEYEGNLLEAGLELERDE
10 20 30
150 160 170 180 190 200
pF1KE2 DTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQ
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE2 PKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSM
100 110 120 130 140 150
270 280 290 300
pF1KE2 G----------------------ITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEE
: :::::::::::::::::::::::::::::::::::::
XP_006 GQGEGRKKDSALLSKRRKCGKYGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEE
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE2 WARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENI
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE2 PSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFM
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE2 EHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEES
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE2 TNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISM
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE2 AAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEE
460 470 480 490 500 510
610 620 630 640 650 660
pF1KE2 RLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQL
520 530 540 550 560 570
670 680 690 700 710 720
pF1KE2 SIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAG
580 590 600 610 620 630
730 740 750 760 770 780
pF1KE2 LTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIG
640 650 660 670 680 690
790 800 810 820 830 840
pF1KE2 IWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQ
700 710 720 730 740 750
850 860 870 880 890 900
pF1KE2 NGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFM
760 770 780 790 800 810
910 920 930 940 950 960
pF1KE2 SDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHN
820 830 840 850 860 870
970 980
pF1KE2 TKACPDSLGSPAPSHAYHGGVL
::::::::::::::::::::::
XP_006 TKACPDSLGSPAPSHAYHGGVL
880 890
>>XP_011543431 (OMIM: 610108) PREDICTED: anoctamin-1 iso (979 aa)
initn: 4852 init1: 4852 opt: 4862 Z-score: 5654.7 bits: 1057.8 E(85289): 0
Smith-Waterman score: 6355; 97.4% identity (97.5% similar) in 977 aa overlap (32-986:5-979)
10 20 30 40 50 60
pF1KE2 RVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRK
::. :::::::::::::::::::::::::
XP_011 MLTRPSQ--LLNSLSVDPDAECKYGLYFRDGRRK
10 20 30
70 80 90 100 110 120
pF1KE2 VDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 DDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKM
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 YHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFF
160 170 180 190 200 210
250 260 270
pF1KE2 DSKTRSTIVYEILKRTTCTKAKYSMG----------------------ITSLLANGVYAA
:::::::::::::::::::::::::: ::::::::::::
XP_011 DSKTRSTIVYEILKRTTCTKAKYSMGQGEGRKKDSALLSKRRKCGKYGITSLLANGVYAA
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE2 AYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYT
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE2 QMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATAR
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE2 ASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYE
400 410 420 430 440 450
460 470 480 490 500 510
pF1KE2 ARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTN
460 470 480 490 500 510
520 530 540 550 560 570
pF1KE2 LVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILL
520 530 540 550 560 570
580 590 600 610 620 630
pF1KE2 DEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDY
580 590 600 610 620 630
640 650 660 670 680 690
pF1KE2 VYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQS
640 650 660 670 680 690
700 710 720 730 740 750
pF1KE2 PPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNII
700 710 720 730 740 750
760 770 780 790 800 810
pF1KE2 EIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLY
760 770 780 790 800 810
820 830 840 850 860 870
pF1KE2 MYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDI
820 830 840 850 860 870
880 890 900 910 920 930
pF1KE2 SKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQ
880 890 900 910 920 930
940 950 960 970 980
pF1KE2 DKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
940 950 960 970
>>XP_006718665 (OMIM: 610108) PREDICTED: anoctamin-1 iso (980 aa)
initn: 4852 init1: 4852 opt: 4862 Z-score: 5654.7 bits: 1057.8 E(85289): 0
Smith-Waterman score: 6357; 97.4% identity (97.6% similar) in 977 aa overlap (32-986:5-980)
10 20 30 40 50 60
pF1KE2 RVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRK
::. .:::::::::::::::::::::::::
XP_006 MLTRPSQ-VLLNSLSVDPDAECKYGLYFRDGRRK
10 20 30
70 80 90 100 110 120
pF1KE2 VDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 DDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKM
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 YHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFF
160 170 180 190 200 210
250 260 270
pF1KE2 DSKTRSTIVYEILKRTTCTKAKYSMG----------------------ITSLLANGVYAA
:::::::::::::::::::::::::: ::::::::::::
XP_006 DSKTRSTIVYEILKRTTCTKAKYSMGQGEGRKKDSALLSKRRKCGKYGITSLLANGVYAA
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE2 AYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYT
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE2 QMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATAR
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE2 ASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYE
400 410 420 430 440 450
460 470 480 490 500 510
pF1KE2 ARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTN
460 470 480 490 500 510
520 530 540 550 560 570
pF1KE2 LVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILL
520 530 540 550 560 570
580 590 600 610 620 630
pF1KE2 DEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDY
580 590 600 610 620 630
640 650 660 670 680 690
pF1KE2 VYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQS
640 650 660 670 680 690
700 710 720 730 740 750
pF1KE2 PPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNII
700 710 720 730 740 750
760 770 780 790 800 810
pF1KE2 EIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLY
760 770 780 790 800 810
820 830 840 850 860 870
pF1KE2 MYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDI
820 830 840 850 860 870
880 890 900 910 920 930
pF1KE2 SKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQ
880 890 900 910 920 930
940 950 960 970 980
pF1KE2 DKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
:::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
940 950 960 970 980
>>XP_011543423 (OMIM: 610108) PREDICTED: anoctamin-1 iso (1008 aa)
initn: 4852 init1: 4852 opt: 4862 Z-score: 5654.6 bits: 1057.8 E(85289): 0
Smith-Waterman score: 6588; 97.8% identity (97.8% similar) in 1008 aa overlap (1-986:1-1008)
10 20 30 40 50 60
pF1KE2 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
190 200 210 220 230 240
250 260 270
pF1KE2 FDSKTRSTIVYEILKRTTCTKAKYSMG----------------------ITSLLANGVYA
::::::::::::::::::::::::::: :::::::::::
XP_011 FDSKTRSTIVYEILKRTTCTKAKYSMGQGEGRKKDSALLSKRRKCGKYGITSLLANGVYA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE2 AAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVY
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE2 TQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE2 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE2 EARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLT
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE2 NLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIIL
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE2 LDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGD
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE2 YVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQ
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE2 SPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNI
730 740 750 760 770 780
760 770 780 790 800 810
pF1KE2 IEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYL
790 800 810 820 830 840
820 830 840 850 860 870
pF1KE2 YMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYD
850 860 870 880 890 900
880 890 900 910 920 930
pF1KE2 ISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREE
910 920 930 940 950 960
940 950 960 970 980
pF1KE2 QDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
970 980 990 1000
>>XP_011543425 (OMIM: 610108) PREDICTED: anoctamin-1 iso (1007 aa)
initn: 5381 init1: 3597 opt: 4844 Z-score: 5633.6 bits: 1053.9 E(85289): 0
Smith-Waterman score: 6570; 97.7% identity (97.7% similar) in 1008 aa overlap (1-986:1-1007)
10 20 30 40 50 60
pF1KE2 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSF
190 200 210 220 230 240
250 260 270
pF1KE2 FDSKTRSTIVYEILKRTTCTKAKYSMG----------------------ITSLLANGVYA
::::::::::::::::::::::::::: :::::::::::
XP_011 FDSKTRSTIVYEILKRTTCTKAKYSMGQGEGRKKDSALLSKRRKCGKYGITSLLANGVYA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE2 AAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVY
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE2 TQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATA
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE2 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEY
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_011 RASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEE-AVKDHPRAEY
430 440 450 460 470
460 470 480 490 500 510
pF1KE2 EARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLT
480 490 500 510 520 530
520 530 540 550 560 570
pF1KE2 NLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIIL
540 550 560 570 580 590
580 590 600 610 620 630
pF1KE2 LDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGD
600 610 620 630 640 650
640 650 660 670 680 690
pF1KE2 YVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQ
660 670 680 690 700 710
700 710 720 730 740 750
pF1KE2 SPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNI
720 730 740 750 760 770
760 770 780 790 800 810
pF1KE2 IEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYL
780 790 800 810 820 830
820 830 840 850 860 870
pF1KE2 YMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYD
840 850 860 870 880 890
880 890 900 910 920 930
pF1KE2 ISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREE
900 910 920 930 940 950
940 950 960 970 980
pF1KE2 QDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL
960 970 980 990 1000
986 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:29:07 2016 done: Mon Nov 7 20:29:08 2016
Total Scan time: 12.230 Total Display time: 0.360
Function used was FASTA [36.3.4 Apr, 2011]