Result of FASTA (omim) for
pF1KE2430
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2430, 533 aa
1>>>pF1KE2430 533 - 533 aa - 533 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2201+/-0.000324; mu= 20.2816+/- 0.020
mean_var=83.1745+/-17.251, 0's: 0 Z-trim(118.8): 129 B-trim: 1394 in 2/50
Lambda= 0.140630
statistics sampled from 31907 (32051) to 31907 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.376), width: 16
Scan time: 7.270
The best scores are: opt bits E(85289)
NP_000037 (OMIM: 253200,611542) arylsulfatase B is ( 533) 3754 771.2 0
XP_011541692 (OMIM: 253200,611542) PREDICTED: aryl ( 533) 3754 771.2 0
XP_016864960 (OMIM: 253200,611542) PREDICTED: aryl ( 451) 2825 582.7 8e-166
XP_011541693 (OMIM: 253200,611542) PREDICTED: aryl ( 442) 2819 581.5 1.8e-165
NP_942002 (OMIM: 253200,611542) arylsulfatase B is ( 413) 2797 577.0 3.9e-164
XP_011541694 (OMIM: 253200,611542) PREDICTED: aryl ( 405) 2796 576.8 4.4e-164
XP_011541695 (OMIM: 253200,611542) PREDICTED: aryl ( 382) 2631 543.3 5e-154
XP_005263269 (OMIM: 610010) PREDICTED: arylsulfata ( 596) 1750 364.7 4.5e-100
XP_016864081 (OMIM: 610010) PREDICTED: arylsulfata ( 599) 1750 364.7 4.5e-100
NP_078866 (OMIM: 610010) arylsulfatase J precursor ( 599) 1750 364.7 4.5e-100
NP_001012301 (OMIM: 610009) arylsulfatase I precur ( 569) 1729 360.4 8.3e-99
XP_016864085 (OMIM: 610010) PREDICTED: arylsulfata ( 480) 1462 306.2 1.5e-82
XP_016864083 (OMIM: 610010) PREDICTED: arylsulfata ( 483) 1462 306.2 1.5e-82
XP_016864082 (OMIM: 610010) PREDICTED: arylsulfata ( 483) 1462 306.2 1.5e-82
XP_011530541 (OMIM: 610010) PREDICTED: arylsulfata ( 483) 1462 306.2 1.5e-82
XP_016864084 (OMIM: 610010) PREDICTED: arylsulfata ( 483) 1462 306.2 1.5e-82
XP_011530540 (OMIM: 610010) PREDICTED: arylsulfata ( 492) 1462 306.2 1.5e-82
XP_016864089 (OMIM: 610010) PREDICTED: arylsulfata ( 427) 1262 265.6 2.2e-70
XP_016864088 (OMIM: 610010) PREDICTED: arylsulfata ( 427) 1262 265.6 2.2e-70
XP_016864086 (OMIM: 610010) PREDICTED: arylsulfata ( 427) 1262 265.6 2.2e-70
XP_016864087 (OMIM: 610010) PREDICTED: arylsulfata ( 427) 1262 265.6 2.2e-70
NP_000503 (OMIM: 253000,612222) N-acetylgalactosam ( 522) 539 118.9 3.7e-26
XP_005256358 (OMIM: 253000,612222) PREDICTED: N-ac ( 575) 539 119.0 4e-26
NP_001078896 (OMIM: 250100,607574) arylsulfatase A ( 509) 516 114.3 9.3e-25
NP_000478 (OMIM: 250100,607574) arylsulfatase A is ( 509) 516 114.3 9.3e-25
NP_001078895 (OMIM: 250100,607574) arylsulfatase A ( 509) 516 114.3 9.3e-25
NP_001078894 (OMIM: 250100,607574) arylsulfatase A ( 509) 516 114.3 9.3e-25
XP_016884289 (OMIM: 250100,607574) PREDICTED: aryl ( 547) 516 114.3 9.8e-25
XP_016878601 (OMIM: 253000,612222) PREDICTED: N-ac ( 508) 511 113.3 1.9e-24
XP_016878600 (OMIM: 253000,612222) PREDICTED: N-ac ( 511) 511 113.3 1.9e-24
NP_001310473 (OMIM: 253000,612222) N-acetylgalacto ( 528) 511 113.3 1.9e-24
XP_011521284 (OMIM: 253000,612222) PREDICTED: N-ac ( 581) 511 113.3 2.1e-24
XP_011528993 (OMIM: 250100,607574) PREDICTED: aryl ( 387) 502 111.3 5.4e-24
XP_016885017 (OMIM: 300003) PREDICTED: arylsulfata ( 297) 354 81.2 4.9e-15
XP_011543826 (OMIM: 300003) PREDICTED: arylsulfata ( 462) 354 81.4 6.8e-15
XP_016885016 (OMIM: 300003) PREDICTED: arylsulfata ( 561) 354 81.4 7.8e-15
XP_011543825 (OMIM: 300003) PREDICTED: arylsulfata ( 578) 354 81.4 8e-15
NP_001188467 (OMIM: 300003) arylsulfatase F precur ( 590) 354 81.5 8.1e-15
NP_001188468 (OMIM: 300003) arylsulfatase F precur ( 590) 354 81.5 8.1e-15
NP_004033 (OMIM: 300003) arylsulfatase F precursor ( 590) 354 81.5 8.1e-15
XP_011543824 (OMIM: 300003) PREDICTED: arylsulfata ( 607) 354 81.5 8.3e-15
XP_005274576 (OMIM: 300180,302950) PREDICTED: aryl ( 589) 349 80.4 1.6e-14
NP_000038 (OMIM: 300180,302950) arylsulfatase E is ( 589) 349 80.4 1.6e-14
XP_005274575 (OMIM: 300180,302950) PREDICTED: aryl ( 598) 349 80.4 1.6e-14
NP_001269557 (OMIM: 300180,302950) arylsulfatase E ( 614) 349 80.5 1.7e-14
XP_016885014 (OMIM: 300180,302950) PREDICTED: aryl ( 614) 349 80.5 1.7e-14
XP_006721842 (OMIM: 610008) PREDICTED: arylsulfata ( 329) 334 77.2 8.8e-14
XP_005257229 (OMIM: 610008) PREDICTED: arylsulfata ( 344) 334 77.2 9.1e-14
XP_016879857 (OMIM: 610008) PREDICTED: arylsulfata ( 413) 334 77.3 1e-13
XP_011522847 (OMIM: 610008) PREDICTED: arylsulfata ( 413) 334 77.3 1e-13
>>NP_000037 (OMIM: 253200,611542) arylsulfatase B isofor (533 aa)
initn: 3754 init1: 3754 opt: 3754 Z-score: 4115.7 bits: 771.2 E(85289): 0
Smith-Waterman score: 3754; 99.8% identity (100.0% similar) in 533 aa overlap (1-533:1-533)
10 20 30 40 50 60
pF1KE2 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLMKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_000 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRD
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 PEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM
490 500 510 520 530
>>XP_011541692 (OMIM: 253200,611542) PREDICTED: arylsulf (533 aa)
initn: 3754 init1: 3754 opt: 3754 Z-score: 4115.7 bits: 771.2 E(85289): 0
Smith-Waterman score: 3754; 99.8% identity (100.0% similar) in 533 aa overlap (1-533:1-533)
10 20 30 40 50 60
pF1KE2 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLMKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
XP_011 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRD
430 440 450 460 470 480
490 500 510 520 530
pF1KE2 PEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATGVWGPWM
490 500 510 520 530
>>XP_016864960 (OMIM: 253200,611542) PREDICTED: arylsulf (451 aa)
initn: 2809 init1: 2809 opt: 2825 Z-score: 3098.0 bits: 582.7 E(85289): 8e-166
Smith-Waterman score: 2825; 99.0% identity (99.5% similar) in 413 aa overlap (1-413:1-412)
10 20 30 40 50 60
pF1KE2 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLMKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
XP_016 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLP
::::::::::::::::::::::::::::::::::::::::::::: .:::::
XP_016 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCC-TSMAPASAQLMMR
370 380 390 400 410
430 440 450 460 470 480
pF1KE2 EYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRD
XP_016 PQTEGKGRAGMHMARVAAREMPGSFKEQLFKT
420 430 440 450
>>XP_011541693 (OMIM: 253200,611542) PREDICTED: arylsulf (442 aa)
initn: 2796 init1: 2796 opt: 2819 Z-score: 3091.5 bits: 581.5 E(85289): 1.8e-165
Smith-Waterman score: 2819; 96.9% identity (98.6% similar) in 421 aa overlap (1-420:1-421)
10 20 30 40 50 60
pF1KE2 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLMKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
XP_011 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPC-PRNSMAPAKDDSSL
:::::::::::::::::::::::::::::::::::::::::::: ::. . : ...:.
XP_011 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPSLPRSLVLTAGEEGSV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 PEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDR
:
XP_011 PPPPSLKPLRQFPHLWSKEGIK
430 440
>>NP_942002 (OMIM: 253200,611542) arylsulfatase B isofor (413 aa)
initn: 2796 init1: 2796 opt: 2797 Z-score: 3067.8 bits: 577.0 E(85289): 3.9e-164
Smith-Waterman score: 2797; 98.5% identity (99.3% similar) in 411 aa overlap (1-410:1-411)
10 20 30 40 50 60
pF1KE2 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLMKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_942 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPC-PRNSMAPAKDDSSL
:::::::::::::::::::::::::::::::::::::::::::: :. :.
NP_942 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPYWPECSLLL
370 380 390 400 410
420 430 440 450 460 470
pF1KE2 PEYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDR
>>XP_011541694 (OMIM: 253200,611542) PREDICTED: arylsulf (405 aa)
initn: 2796 init1: 2796 opt: 2796 Z-score: 3066.8 bits: 576.8 E(85289): 4.4e-164
Smith-Waterman score: 2796; 99.8% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KE2 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLMKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
XP_011 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLP
::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPW
370 380 390 400
430 440 450 460 470 480
pF1KE2 EYSAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRD
>>XP_011541695 (OMIM: 253200,611542) PREDICTED: arylsulf (382 aa)
initn: 2631 init1: 2631 opt: 2631 Z-score: 2886.2 bits: 543.3 E(85289): 5e-154
Smith-Waterman score: 2631; 99.7% identity (100.0% similar) in 380 aa overlap (1-380:1-380)
10 20 30 40 50 60
pF1KE2 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLMKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
XP_011 NGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 ARGHTNGTKPLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLP
::::::::::::::::::::
XP_011 ARGHTNGTKPLDGFDVWKTIRC
370 380
>>XP_005263269 (OMIM: 610010) PREDICTED: arylsulfatase J (596 aa)
initn: 1869 init1: 774 opt: 1750 Z-score: 1917.7 bits: 364.7 E(85289): 4.5e-100
Smith-Waterman score: 1858; 53.7% identity (77.2% similar) in 501 aa overlap (41-532:72-554)
20 30 40 50 60 70
pF1KE2 RGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTP
.. :::.:.:::: :. :::.:::.:.::
XP_005 GYLSWGQALEEEEEGALLAQAGEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTP
50 60 70 80 90 100
80 90 100 110 120 130
pF1KE2 HLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLP
:: ::: :: :.:::.::.:::::::..::.:::.:::::.:: : ::.:.:::. ::
XP_005 TLDKLAAEGVKLENYYVQPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLP
110 120 130 140 150 160
140 150 160 170 180 190
pF1KE2 QLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVT
: :::.::.::::::::::.:::::.::::::::.:: :::: :::.: .: :. ..
XP_005 QKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGSLLGSGDYYTHYKC---DSPGM-
170 180 190 200 210
200 210 220 230 240
pF1KE2 RCALDFRDGEEVATGYKN-MYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPE
:. :. .....: : : .:::...:.:. ....: : ::.:::.: :.:: :::.:
XP_005 -CGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPIFLYIAYQAVHSPLQAPG
220 230 240 250 260 270
250 260 270 280 290 300
pF1KE2 EYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG
.:.. : : . ::..::.:.: .:::..::: :::. :..::...:.:.::::: :::
XP_005 RYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNGGQPTAGG
280 290 300 310 320 330
310 320 330 340 350 360
pF1KE2 NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLMKLARGHTNGTK
.:::::: : . ::::.:.:::: :::::.::. .::.::.:: :::..::.:. .
XP_005 SNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQIDEDI
340 350 360 370 380 390
370 380 390 400 410 420
pF1KE2 PLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSV
:::.:.:.::::: :::...:::::: .. ::. : :. .::..
XP_005 QLDGYDIWETISEGLRSPRVDILHNIDPIYTK-----------AKNGSWAAGYGIWNTAI
400 410 420 430 440
430 440 450 460 470 480
pF1KE2 HAAIRHGNWKLLTGYPGCGYWFPP-------PSQYNVSEIPSSDPPTKTLWLFDIDRDPE
..::: .:::::: :: . : :: :.... .: : :..:::.: ::
XP_005 QSAIRVQHWKLLTGNPGYSDWVPPQSFSNLGPNRWHNERITLSTG--KSVWLFNITADPY
450 460 470 480 490 500
490 500 510 520 530
pF1KE2 ERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATG-VWGPWM
:: ::: .:: :: ::: ::. ..: .::: .: .::: .:. .: :::::
XP_005 ERVDLSNRYPGIVKKLLRRLSQFNKTAVPVRYPPKDPRSNPRLNGGVWGPWYKEETKKKK
510 520 530 540 550 560
XP_005 PSKNQAEKKQKKSKKKKKKQQKAVSGKPANLAR
570 580 590
>>XP_016864081 (OMIM: 610010) PREDICTED: arylsulfatase J (599 aa)
initn: 1869 init1: 774 opt: 1750 Z-score: 1917.6 bits: 364.7 E(85289): 4.5e-100
Smith-Waterman score: 1858; 53.7% identity (77.2% similar) in 501 aa overlap (41-532:72-554)
20 30 40 50 60 70
pF1KE2 RGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTP
.. :::.:.:::: :. :::.:::.:.::
XP_016 GYLSWGQALEEEEEGALLAQAGEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTP
50 60 70 80 90 100
80 90 100 110 120 130
pF1KE2 HLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLP
:: ::: :: :.:::.::.:::::::..::.:::.:::::.:: : ::.:.:::. ::
XP_016 TLDKLAAEGVKLENYYVQPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLP
110 120 130 140 150 160
140 150 160 170 180 190
pF1KE2 QLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVT
: :::.::.::::::::::.:::::.::::::::.:: :::: :::.: .: :. ..
XP_016 QKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGSLLGSGDYYTHYKC---DSPGM-
170 180 190 200 210
200 210 220 230 240
pF1KE2 RCALDFRDGEEVATGYKN-MYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPE
:. :. .....: : : .:::...:.:. ....: : ::.:::.: :.:: :::.:
XP_016 -CGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPIFLYIAYQAVHSPLQAPG
220 230 240 250 260 270
250 260 270 280 290 300
pF1KE2 EYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG
.:.. : : . ::..::.:.: .:::..::: :::. :..::...:.:.::::: :::
XP_016 RYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNGGQPTAGG
280 290 300 310 320 330
310 320 330 340 350 360
pF1KE2 NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLMKLARGHTNGTK
.:::::: : . ::::.:.:::: :::::.::. .::.::.:: :::..::.:. .
XP_016 SNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQIDEDI
340 350 360 370 380 390
370 380 390 400 410 420
pF1KE2 PLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSV
:::.:.:.::::: :::...:::::: .. ::. : :. .::..
XP_016 QLDGYDIWETISEGLRSPRVDILHNIDPIYTK-----------AKNGSWAAGYGIWNTAI
400 410 420 430 440
430 440 450 460 470 480
pF1KE2 HAAIRHGNWKLLTGYPGCGYWFPP-------PSQYNVSEIPSSDPPTKTLWLFDIDRDPE
..::: .:::::: :: . : :: :.... .: : :..:::.: ::
XP_016 QSAIRVQHWKLLTGNPGYSDWVPPQSFSNLGPNRWHNERITLSTG--KSVWLFNITADPY
450 460 470 480 490 500
490 500 510 520 530
pF1KE2 ERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATG-VWGPWM
:: ::: .:: :: ::: ::. ..: .::: .: .::: .:. .: :::::
XP_016 ERVDLSNRYPGIVKKLLRRLSQFNKTAVPVRYPPKDPRSNPRLNGGVWGPWYKEETKKKK
510 520 530 540 550 560
XP_016 PSKNQAEKKQKKSKKKKKKQQKAVSGSTCHSGVTCG
570 580 590
>>NP_078866 (OMIM: 610010) arylsulfatase J precursor [Ho (599 aa)
initn: 1869 init1: 774 opt: 1750 Z-score: 1917.6 bits: 364.7 E(85289): 4.5e-100
Smith-Waterman score: 1858; 53.7% identity (77.2% similar) in 501 aa overlap (41-532:72-554)
20 30 40 50 60 70
pF1KE2 RGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTP
.. :::.:.:::: :. :::.:::.:.::
NP_078 GYLSWGQALEEEEEGALLAQAGEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTP
50 60 70 80 90 100
80 90 100 110 120 130
pF1KE2 HLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLP
:: ::: :: :.:::.::.:::::::..::.:::.:::::.:: : ::.:.:::. ::
NP_078 TLDKLAAEGVKLENYYVQPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLP
110 120 130 140 150 160
140 150 160 170 180 190
pF1KE2 QLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVT
: :::.::.::::::::::.:::::.::::::::.:: :::: :::.: .: :. ..
NP_078 QKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGSLLGSGDYYTHYKC---DSPGM-
170 180 190 200 210
200 210 220 230 240
pF1KE2 RCALDFRDGEEVATGYKN-MYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPE
:. :. .....: : : .:::...:.:. ....: : ::.:::.: :.:: :::.:
NP_078 -CGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPIFLYIAYQAVHSPLQAPG
220 230 240 250 260 270
250 260 270 280 290 300
pF1KE2 EYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQTLAGG
.:.. : : . ::..::.:.: .:::..::: :::. :..::...:.:.::::: :::
NP_078 RYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNGGQPTAGG
280 290 300 310 320 330
310 320 330 340 350 360
pF1KE2 NNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLMKLARGHTNGTK
.:::::: : . ::::.:.:::: :::::.::. .::.::.:: :::..::.:. .
NP_078 SNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQIDEDI
340 350 360 370 380 390
370 380 390 400 410 420
pF1KE2 PLDGFDVWKTISEGSPSPRIELLHNIDPNFVDSSPCPRNSMAPAKDDSSLPEYSAFNTSV
:::.:.:.::::: :::...:::::: .. ::. : :. .::..
NP_078 QLDGYDIWETISEGLRSPRVDILHNIDPIYTK-----------AKNGSWAAGYGIWNTAI
400 410 420 430 440
430 440 450 460 470 480
pF1KE2 HAAIRHGNWKLLTGYPGCGYWFPP-------PSQYNVSEIPSSDPPTKTLWLFDIDRDPE
..::: .:::::: :: . : :: :.... .: : :..:::.: ::
NP_078 QSAIRVQHWKLLTGNPGYSDWVPPQSFSNLGPNRWHNERITLSTG--KSVWLFNITADPY
450 460 470 480 490 500
490 500 510 520 530
pF1KE2 ERHDLSREYPHIVTKLLSRLQFYHKHSVPVYFPAQDPRCDPKATG-VWGPWM
:: ::: .:: :: ::: ::. ..: .::: .: .::: .:. .: :::::
NP_078 ERVDLSNRYPGIVKKLLRRLSQFNKTAVPVRYPPKDPRSNPRLNGGVWGPWYKEETKKKK
510 520 530 540 550 560
NP_078 PSKNQAEKKQKKSKKKKKKQQKAVSGSTCHSGVTCG
570 580 590
533 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:58:18 2016 done: Mon Nov 7 19:58:19 2016
Total Scan time: 7.270 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]