Result of FASTA (omim) for
pF1KE2381
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2381, 1490 aa
1>>>pF1KE2381 1490 - 1490 aa - 1490 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 19.8588+/-0.000539; mu= -42.3378+/- 0.034
mean_var=1075.9156+/-233.164, 0's: 0 Z-trim(124.8): 420 B-trim: 2752 in 1/61
Lambda= 0.039101
statistics sampled from 46709 (47209) to 46709 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.554), width: 16
Scan time: 22.860
The best scores are: opt bits E(85289)
NP_057591 (OMIM: 615514) cyclin-dependent kinase 1 (1490) 9956 578.6 1.3e-163
XP_005257513 (OMIM: 615514) PREDICTED: cyclin-depe (1489) 9939 577.6 2.5e-163
XP_011523200 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523199 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_016880233 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523198 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523196 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523195 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523201 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_016880234 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_016880238 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523208 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_016880237 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_016880236 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523204 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523203 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523202 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_016880235 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523197 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523205 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
XP_011523207 (OMIM: 615514) PREDICTED: cyclin-depe (1393) 9284 540.7 3.1e-152
NP_055898 (OMIM: 615514) cyclin-dependent kinase 1 (1481) 8393 490.4 4.4e-137
XP_005257515 (OMIM: 615514) PREDICTED: cyclin-depe (1256) 8299 485.1 1.5e-135
XP_016880239 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 8299 485.1 1.5e-135
XP_016880241 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 8299 485.1 1.5e-135
XP_016880240 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 8299 485.1 1.5e-135
XP_011523209 (OMIM: 615514) PREDICTED: cyclin-depe (1262) 8299 485.1 1.5e-135
XP_016880242 (OMIM: 615514) PREDICTED: cyclin-depe (1261) 8282 484.1 3e-135
XP_011523194 (OMIM: 615514) PREDICTED: cyclin-depe (1464) 6147 363.7 6e-99
NP_003709 (OMIM: 603309) cyclin-dependent kinase 1 (1512) 2928 182.1 2.8e-44
NP_112557 (OMIM: 603309) cyclin-dependent kinase 1 (1452) 2678 168.0 4.8e-40
XP_016868240 (OMIM: 603309) PREDICTED: cyclin-depe (1482) 1619 108.3 4.7e-22
XP_011513899 (OMIM: 603309) PREDICTED: cyclin-depe ( 905) 1589 106.4 1e-21
XP_016868239 (OMIM: 603309) PREDICTED: cyclin-depe (1542) 1589 106.6 1.6e-21
NP_001252 (OMIM: 603251) cyclin-dependent kinase 9 ( 372) 979 71.7 1.2e-11
XP_016870050 (OMIM: 610076) PREDICTED: cyclin-depe ( 351) 764 59.6 5.1e-08
XP_016870051 (OMIM: 610076) PREDICTED: cyclin-depe ( 329) 747 58.6 9.4e-08
NP_001250 (OMIM: 603368,616080) cyclin-dependent k ( 326) 673 54.4 1.7e-06
NP_001138778 (OMIM: 603368,616080) cyclin-dependen ( 326) 673 54.4 1.7e-06
XP_006715898 (OMIM: 603368,616080) PREDICTED: cycl ( 326) 673 54.4 1.7e-06
NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 660 54.0 5.7e-06
NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 660 54.0 5.7e-06
NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 660 54.0 5.7e-06
XP_006721621 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 655 53.7 7e-06
XP_006721622 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 655 53.7 7e-06
XP_006721620 (OMIM: 602521) PREDICTED: mitogen-act ( 822) 655 53.7 7e-06
NP_000066 (OMIM: 123829,609048) cyclin-dependent k ( 303) 624 51.7 1.1e-05
NP_001034892 (OMIM: 610076) cyclin-dependent kinas ( 346) 622 51.6 1.3e-05
NP_001790 (OMIM: 601955) cyclin-dependent kinase 7 ( 346) 618 51.4 1.5e-05
XP_016869673 (OMIM: 603251) PREDICTED: cyclin-depe ( 243) 610 50.8 1.6e-05
>>NP_057591 (OMIM: 615514) cyclin-dependent kinase 12 is (1490 aa)
initn: 9956 init1: 9956 opt: 9956 Z-score: 3058.5 bits: 578.6 E(85289): 1.3e-163
Smith-Waterman score: 9956; 99.9% identity (99.9% similar) in 1490 aa overlap (1-1490:1-1490)
10 20 30 40 50 60
pF1KE2 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQMTLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_057 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490
pF1KE2 GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY
1450 1460 1470 1480 1490
>>XP_005257513 (OMIM: 615514) PREDICTED: cyclin-dependen (1489 aa)
initn: 7651 init1: 7651 opt: 9939 Z-score: 3053.4 bits: 577.6 E(85289): 2.5e-163
Smith-Waterman score: 9939; 99.9% identity (99.9% similar) in 1490 aa overlap (1-1490:1-1489)
10 20 30 40 50 60
pF1KE2 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_005 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLP-RKSMKSRSRSP
310 320 330 340 350
370 380 390 400 410 420
pF1KE2 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE2 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE2 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE2 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE2 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE2 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE2 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE2 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE2 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE2 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQMTLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_005 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE2 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE2 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE2 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE2 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490
pF1KE2 GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY
1440 1450 1460 1470 1480
>>XP_011523200 (OMIM: 615514) PREDICTED: cyclin-dependen (1393 aa)
initn: 9284 init1: 9284 opt: 9284 Z-score: 2854.1 bits: 540.7 E(85289): 3.1e-152
Smith-Waterman score: 9284; 99.9% identity (99.9% similar) in 1393 aa overlap (1-1393:1-1393)
10 20 30 40 50 60
pF1KE2 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQMTLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
:::::::::::::
XP_011 SHLGESSSYQGTG
1390
>>XP_011523199 (OMIM: 615514) PREDICTED: cyclin-dependen (1393 aa)
initn: 9284 init1: 9284 opt: 9284 Z-score: 2854.1 bits: 540.7 E(85289): 3.1e-152
Smith-Waterman score: 9284; 99.9% identity (99.9% similar) in 1393 aa overlap (1-1393:1-1393)
10 20 30 40 50 60
pF1KE2 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQMTLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
:::::::::::::
XP_011 SHLGESSSYQGTG
1390
>>XP_016880233 (OMIM: 615514) PREDICTED: cyclin-dependen (1393 aa)
initn: 9284 init1: 9284 opt: 9284 Z-score: 2854.1 bits: 540.7 E(85289): 3.1e-152
Smith-Waterman score: 9284; 99.9% identity (99.9% similar) in 1393 aa overlap (1-1393:1-1393)
10 20 30 40 50 60
pF1KE2 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQMTLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
:::::::::::::
XP_016 SHLGESSSYQGTG
1390
>>XP_011523198 (OMIM: 615514) PREDICTED: cyclin-dependen (1393 aa)
initn: 9284 init1: 9284 opt: 9284 Z-score: 2854.1 bits: 540.7 E(85289): 3.1e-152
Smith-Waterman score: 9284; 99.9% identity (99.9% similar) in 1393 aa overlap (1-1393:1-1393)
10 20 30 40 50 60
pF1KE2 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQMTLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
:::::::::::::
XP_011 SHLGESSSYQGTG
1390
>>XP_011523196 (OMIM: 615514) PREDICTED: cyclin-dependen (1393 aa)
initn: 9284 init1: 9284 opt: 9284 Z-score: 2854.1 bits: 540.7 E(85289): 3.1e-152
Smith-Waterman score: 9284; 99.9% identity (99.9% similar) in 1393 aa overlap (1-1393:1-1393)
10 20 30 40 50 60
pF1KE2 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQMTLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
:::::::::::::
XP_011 SHLGESSSYQGTG
1390
>>XP_011523195 (OMIM: 615514) PREDICTED: cyclin-dependen (1393 aa)
initn: 9284 init1: 9284 opt: 9284 Z-score: 2854.1 bits: 540.7 E(85289): 3.1e-152
Smith-Waterman score: 9284; 99.9% identity (99.9% similar) in 1393 aa overlap (1-1393:1-1393)
10 20 30 40 50 60
pF1KE2 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQMTLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
:::::::::::::
XP_011 SHLGESSSYQGTG
1390
>>XP_011523201 (OMIM: 615514) PREDICTED: cyclin-dependen (1393 aa)
initn: 9284 init1: 9284 opt: 9284 Z-score: 2854.1 bits: 540.7 E(85289): 3.1e-152
Smith-Waterman score: 9284; 99.9% identity (99.9% similar) in 1393 aa overlap (1-1393:1-1393)
10 20 30 40 50 60
pF1KE2 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQMTLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_011 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
:::::::::::::
XP_011 SHLGESSSYQGTG
1390
>>XP_016880234 (OMIM: 615514) PREDICTED: cyclin-dependen (1393 aa)
initn: 9284 init1: 9284 opt: 9284 Z-score: 2854.1 bits: 540.7 E(85289): 3.1e-152
Smith-Waterman score: 9284; 99.9% identity (99.9% similar) in 1393 aa overlap (1-1393:1-1393)
10 20 30 40 50 60
pF1KE2 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQMTLEAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
:::::::::::::
XP_016 SHLGESSSYQGTG
1390
1490 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:51:50 2016 done: Sun Nov 6 13:51:53 2016
Total Scan time: 22.860 Total Display time: 0.640
Function used was FASTA [36.3.4 Apr, 2011]