Result of FASTA (omim) for
pF1KE2351
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2351, 468 aa
1>>>pF1KE2351 468 - 468 aa - 468 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6357+/-0.000379; mu= 16.0506+/- 0.024
mean_var=74.4619+/-15.045, 0's: 0 Z-trim(113.5): 7 B-trim: 304 in 1/54
Lambda= 0.148630
statistics sampled from 22806 (22811) to 22806 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.267), width: 16
Scan time: 9.300
The best scores are: opt bits E(85289)
NP_055399 (OMIM: 615435) ERO1-like protein alpha p ( 468) 3236 703.5 3.2e-202
XP_011534986 (OMIM: 615435) PREDICTED: ERO1-like p ( 464) 3194 694.5 1.6e-199
NP_063944 (OMIM: 615437) ERO1-like protein beta pr ( 467) 2027 444.2 3.5e-124
XP_016857323 (OMIM: 615437) PREDICTED: ERO1-like p ( 263) 871 196.2 8.9e-50
>>NP_055399 (OMIM: 615435) ERO1-like protein alpha precu (468 aa)
initn: 3236 init1: 3236 opt: 3236 Z-score: 3751.6 bits: 703.5 E(85289): 3.2e-202
Smith-Waterman score: 3236; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:1-468)
10 20 30 40 50 60
pF1KE2 MGRGWGFLFGLLGAVWLLSSGHGEEQPPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MGRGWGFLFGLLGAVWLLSSGHGEEQPPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 SEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CVEKRAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CVEKRAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKL
370 380 390 400 410 420
430 440 450 460
pF1KE2 IANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH
::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH
430 440 450 460
>>XP_011534986 (OMIM: 615435) PREDICTED: ERO1-like prote (464 aa)
initn: 1610 init1: 1610 opt: 3194 Z-score: 3703.0 bits: 694.5 E(85289): 1.6e-199
Smith-Waterman score: 3194; 99.1% identity (99.1% similar) in 468 aa overlap (1-468:1-464)
10 20 30 40 50 60
pF1KE2 MGRGWGFLFGLLGAVWLLSSGHGEEQPPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGRGWGFLFGLLGAVWLLSSGHGEEQPPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 SEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGL
::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_011 LLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQ----ENTFYSWLEGL
190 200 210 220 230
250 260 270 280 290 300
pF1KE2 CVEKRAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVEKRAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 LKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 NSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKL
360 370 380 390 400 410
430 440 450 460
pF1KE2 IANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH
420 430 440 450 460
>>NP_063944 (OMIM: 615437) ERO1-like protein beta precur (467 aa)
initn: 2006 init1: 1624 opt: 2027 Z-score: 2350.6 bits: 444.2 E(85289): 3.5e-124
Smith-Waterman score: 2027; 64.8% identity (87.3% similar) in 432 aa overlap (38-466:34-465)
10 20 30 40 50 60
pF1KE2 LFGLLGAVWLLSSGHGEEQPPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQK
::.: :::: ::...:: ::.:..::...:
NP_063 GVRRAGAGQGVAAAVQLLVTLSFLRSVVEAQVTGVLDDCLCDIDSIDNFNTYKIFPKIKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSA-SYKYSEEANN
: : ::::::::::::::::: . ..:. .:: :.:: ...: :::.. : :: . :::
NP_063 LQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGHSNKYLKMANN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 L--IEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLN
.:.::::..:::.. .::.....: ..:...::: :.::: :: .:: :.:::::::
NP_063 TKELEDCEQANKLGAINSTLSNQSKEAFIDWARYDDSRDHFCELDDERSPAAQYVDLLLN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 PERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGLCVEK
::::::::: .::..:: :::::::::... ::::::: ..: .. ..::.::::::.::
NP_063 PERYTGYKGTSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 RAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNL
:.::.::::::::::.:: : :::.::: . .:: :: ::..::: . :.::::::::::
NP_063 RVFYKLISGLHASINLHLCANYLLEETWGKPSWGPNIKEFKHRFDPVETKGEGPRRLKNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 YFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDENSFF
:::::::::::::: :.::: .:.::: .: ..: :::.:... ::::.::::.:.:
NP_063 YFLYLIELRALSKVAPYFERSIVDLYTGNAEEDADTKTLLLNIFQDTKSFPMHFDEKSMF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKLIANM
::::: :..:::.:::::.::::::::::: :::::::::::::::::::::::: : ..
NP_063 AGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKL
370 380 390 400 410 420
430 440 450 460
pF1KE2 PESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH
::..:: :.:::::::.:.:::::.:::...:.::. :::.
NP_063 PENSPSKGFQLTRQEIVALLNAFGRLSTSIRDLQNFKVLLQHSR
430 440 450 460
>>XP_016857323 (OMIM: 615437) PREDICTED: ERO1-like prote (263 aa)
initn: 478 init1: 478 opt: 871 Z-score: 1014.7 bits: 196.2 E(85289): 8.9e-50
Smith-Waterman score: 871; 59.6% identity (85.1% similar) in 188 aa overlap (38-222:34-221)
10 20 30 40 50 60
pF1KE2 LFGLLGAVWLLSSGHGEEQPPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQK
::.: :::: ::...:: ::.:..::...:
XP_016 GVRRAGAGQGVAAAVQLLVTLSFLRSVVEAQVTGVLDDCLCDIDSIDNFNTYKIFPKIKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSA-SYKYSEEANN
: : ::::::::::::::::: . ..:. .:: :.:: ...: :::.. : :: . :::
XP_016 LQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGHSNKYLKMANN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 L--IEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLN
.:.::::..:::.. .::.....: ..:...::: :.::: :: .:: :.:::::::
XP_016 TKELEDCEQANKLGAINSTLSNQSKEAFIDWARYDDSRDHFCELDDERSPAAQYVDLLLN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 PERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGLCVEK
::::::::: .::..:: :::::::::... :::::::
XP_016 PERYTGYKGTSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRVIYQRHNTAEKMRKRKLLH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 RAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNL
XP_016 RKRGREEEKRRKMKYERRQD
250 260
468 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:25:39 2016 done: Sun Nov 6 14:25:40 2016
Total Scan time: 9.300 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]