Result of FASTA (omim) for
pF1KE2342
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2342, 423 aa
1>>>pF1KE2342 423 - 423 aa - 423 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1793+/-0.00042; mu= 18.1952+/- 0.026
mean_var=67.1828+/-13.485, 0's: 0 Z-trim(110.3): 62 B-trim: 1031 in 1/52
Lambda= 0.156475
statistics sampled from 18600 (18662) to 18600 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.583), E-opt: 0.2 (0.219), width: 16
Scan time: 7.550
The best scores are: opt bits E(85289)
NP_002216 (OMIM: 243500,607036) isovaleryl-CoA deh ( 426) 2802 641.8 9.4e-184
XP_016877645 (OMIM: 243500,607036) PREDICTED: isov ( 407) 2520 578.2 1.3e-164
XP_005254407 (OMIM: 243500,607036) PREDICTED: isov ( 487) 2518 577.8 2.1e-164
XP_006720555 (OMIM: 243500,607036) PREDICTED: isov ( 447) 2511 576.2 5.8e-164
NP_001152980 (OMIM: 243500,607036) isovaleryl-CoA ( 396) 2321 533.2 4.3e-151
XP_016877643 (OMIM: 243500,607036) PREDICTED: isov ( 436) 2307 530.1 4.2e-150
XP_016877641 (OMIM: 243500,607036) PREDICTED: isov ( 455) 2307 530.1 4.3e-150
XP_006720558 (OMIM: 243500,607036) PREDICTED: isov ( 347) 2089 480.8 2.3e-135
XP_016877638 (OMIM: 243500,607036) PREDICTED: isov ( 516) 2023 466.0 9.5e-131
XP_016877640 (OMIM: 243500,607036) PREDICTED: isov ( 476) 2016 464.4 2.7e-130
XP_016877639 (OMIM: 243500,607036) PREDICTED: isov ( 478) 2016 464.4 2.7e-130
XP_016877644 (OMIM: 243500,607036) PREDICTED: isov ( 418) 2011 463.3 5.3e-130
XP_016877642 (OMIM: 243500,607036) PREDICTED: isov ( 447) 2010 463.1 6.5e-130
XP_016877646 (OMIM: 243500,607036) PREDICTED: isov ( 376) 1594 369.1 1.1e-101
XP_016877647 (OMIM: 243500,607036) PREDICTED: isov ( 308) 1204 281.0 2.8e-75
NP_000008 (OMIM: 201470,606885) short-chain specif ( 412) 866 204.8 3.4e-52
NP_001600 (OMIM: 600301,610006) short/branched cha ( 432) 848 200.7 5.8e-51
XP_005246574 (OMIM: 609576) PREDICTED: long-chain ( 409) 814 193.0 1.1e-48
NP_001599 (OMIM: 609576) long-chain specific acyl- ( 430) 814 193.1 1.2e-48
NP_001272971 (OMIM: 201450,607008) medium-chain sp ( 385) 782 185.8 1.6e-46
NP_000007 (OMIM: 201450,607008) medium-chain speci ( 421) 782 185.8 1.7e-46
NP_001120800 (OMIM: 201450,607008) medium-chain sp ( 425) 782 185.8 1.8e-46
NP_054768 (OMIM: 611103,611126) acyl-CoA dehydroge ( 621) 772 183.7 1.1e-45
NP_055199 (OMIM: 604773,611283) isobutyryl-CoA deh ( 415) 766 182.2 2.1e-45
NP_001317103 (OMIM: 600301,610006) short/branched ( 330) 762 181.2 3.3e-45
XP_016873032 (OMIM: 604773,611283) PREDICTED: isob ( 434) 727 173.4 9.8e-43
XP_011541052 (OMIM: 604773,611283) PREDICTED: isob ( 451) 727 173.4 1e-42
XP_016873031 (OMIM: 604773,611283) PREDICTED: isob ( 451) 727 173.4 1e-42
NP_001257377 (OMIM: 201475,609575) very long-chain ( 579) 717 171.2 5.9e-42
XP_011522132 (OMIM: 201475,609575) PREDICTED: very ( 621) 717 171.3 6.2e-42
XP_011522131 (OMIM: 201475,609575) PREDICTED: very ( 628) 717 171.3 6.3e-42
NP_001029031 (OMIM: 201475,609575) very long-chain ( 633) 717 171.3 6.3e-42
NP_000009 (OMIM: 201475,609575) very long-chain sp ( 655) 717 171.3 6.5e-42
XP_006721579 (OMIM: 201475,609575) PREDICTED: very ( 662) 717 171.3 6.6e-42
NP_001257376 (OMIM: 201475,609575) very long-chain ( 678) 717 171.3 6.7e-42
NP_001289483 (OMIM: 201470,606885) short-chain spe ( 408) 700 167.3 6.4e-41
NP_001272972 (OMIM: 201450,607008) medium-chain sp ( 454) 694 166.0 1.8e-40
XP_016861753 (OMIM: 611103,611126) PREDICTED: acyl ( 537) 685 164.0 8.3e-40
XP_016859444 (OMIM: 609576) PREDICTED: long-chain ( 289) 666 159.5 9.8e-39
XP_016873034 (OMIM: 604773,611283) PREDICTED: isob ( 391) 657 157.6 5.1e-38
XP_016873033 (OMIM: 604773,611283) PREDICTED: isob ( 391) 657 157.6 5.1e-38
XP_016873036 (OMIM: 604773,611283) PREDICTED: isob ( 317) 628 151.0 4e-36
XP_016873035 (OMIM: 604773,611283) PREDICTED: isob ( 353) 589 142.2 2e-33
NP_000150 (OMIM: 231670,608801) glutaryl-CoA dehyd ( 438) 561 135.9 1.9e-31
NP_039663 (OMIM: 231670,608801) glutaryl-CoA dehyd ( 428) 533 129.6 1.5e-29
XP_006722784 (OMIM: 231670,608801) PREDICTED: glut ( 442) 526 128.1 4.5e-29
XP_016882069 (OMIM: 231670,608801) PREDICTED: glut ( 442) 526 128.1 4.5e-29
XP_011526202 (OMIM: 231670,608801) PREDICTED: glut ( 443) 526 128.1 4.5e-29
XP_011526201 (OMIM: 231670,608801) PREDICTED: glut ( 446) 526 128.1 4.6e-29
NP_001272973 (OMIM: 201450,607008) medium-chain sp ( 232) 467 114.6 2.7e-25
>>NP_002216 (OMIM: 243500,607036) isovaleryl-CoA dehydro (426 aa)
initn: 2802 init1: 2802 opt: 2802 Z-score: 3419.9 bits: 641.8 E(85289): 9.4e-184
Smith-Waterman score: 2802; 99.8% identity (99.8% similar) in 423 aa overlap (1-423:4-426)
10 20 30 40 50
pF1KE2 MATATRLLGCRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 QEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 VLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 AGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRA
370 380 390 400 410 420
420
pF1KE2 FNADFH
::::::
NP_002 FNADFH
>>XP_016877645 (OMIM: 243500,607036) PREDICTED: isovaler (407 aa)
initn: 2520 init1: 2520 opt: 2520 Z-score: 3076.2 bits: 578.2 E(85289): 1.3e-164
Smith-Waterman score: 2520; 98.4% identity (99.5% similar) in 384 aa overlap (40-423:24-407)
10 20 30 40 50 60
pF1KE2 CRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFLQEHLAPKAQEID
..:. :: .:::::::::::::::::::::
XP_016 MVFWWRIGQATYRLWHKGPQSVCSSLTPEQAELRQTMAKFLQEHLAPKAQEID
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 RSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAH
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 SNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYIL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 NGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSN
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 TCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 EAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECAT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 QVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH
360 370 380 390 400
>>XP_005254407 (OMIM: 243500,607036) PREDICTED: isovaler (487 aa)
initn: 2511 init1: 2511 opt: 2518 Z-score: 3072.6 bits: 577.8 E(85289): 2.1e-164
Smith-Waterman score: 2518; 97.4% identity (98.2% similar) in 392 aa overlap (1-392:4-394)
10 20 30 40 50
pF1KE2 MATATRLLGCRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 QEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 VLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 AGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRA
::::::::::::::::::::::: . . . : ::
XP_005 AGVILYSAECATQVALDGIQCFGQT-FSAQHPPGREGETRGQTSLEQVSTARELRCKILL
370 380 390 400 410
420
pF1KE2 FNADFH
XP_005 PELTPRVLLPQLASWISDQKLPFLKILLCSPTSLGQSSLAGFTKLRWPYPLLQPHLLPHP
420 430 440 450 460 470
>>XP_006720555 (OMIM: 243500,607036) PREDICTED: isovaler (447 aa)
initn: 2511 init1: 2511 opt: 2511 Z-score: 3064.6 bits: 576.2 E(85289): 5.8e-164
Smith-Waterman score: 2511; 99.7% identity (99.7% similar) in 380 aa overlap (1-380:4-383)
10 20 30 40 50
pF1KE2 MATATRLLGCRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 QEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 VLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 AGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRA
:::::::::::::::::::::::
XP_006 AGVILYSAECATQVALDGIQCFGHAPQPFLYTEPVNYQAPRKFFSGSQHLADLFRPTPTW
370 380 390 400 410 420
>>NP_001152980 (OMIM: 243500,607036) isovaleryl-CoA dehy (396 aa)
initn: 2308 init1: 2308 opt: 2321 Z-score: 2833.5 bits: 533.2 E(85289): 4.3e-151
Smith-Waterman score: 2539; 92.7% identity (92.7% similar) in 423 aa overlap (1-423:4-396)
10 20 30 40 50
pF1KE2 MATATRLLGCRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQ---------
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 QEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
:::::::::::::::::::::::::::::::::::::::
NP_001 ---------------------EFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
60 70 80 90
120 130 140 150 160 170
pF1KE2 ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE2 LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE2 KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE2 VLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE2 AGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRA
340 350 360 370 380 390
420
pF1KE2 FNADFH
::::::
NP_001 FNADFH
>>XP_016877643 (OMIM: 243500,607036) PREDICTED: isovaler (436 aa)
initn: 2307 init1: 2307 opt: 2307 Z-score: 2815.9 bits: 530.1 E(85289): 4.2e-150
Smith-Waterman score: 2452; 91.5% identity (92.5% similar) in 413 aa overlap (40-423:24-436)
10 20 30 40 50 60
pF1KE2 CRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFLQEHLAPKAQEID
..:. :: .:::::::::::::::::::::
XP_016 MVFWWRIGQATYRLWHKGPQSVCSSLTPEQAELRQTMAKFLQEHLAPKAQEID
10 20 30 40 50
70 80 90 100
pF1KE2 RSNEFKNLR-----------------------------EFWKQLGNLGVLGITAPVQYGG
::::::::: ::::::::::::::::::::::
XP_016 RSNEFKNLRVSWEVRAVGGSQGVGLSCTAAWKSSHSFLEFWKQLGNLGVLGITAPVQYGG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 SGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 ALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 GITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGL
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 DLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYV
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE2 YNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDFPMGRFLRDAKLY
360 370 380 390 400 410
410 420
pF1KE2 EIGAGTSEVRRLVIGRAFNADFH
:::::::::::::::::::::::
XP_016 EIGAGTSEVRRLVIGRAFNADFH
420 430
>>XP_016877641 (OMIM: 243500,607036) PREDICTED: isovaler (455 aa)
initn: 2307 init1: 2307 opt: 2307 Z-score: 2815.6 bits: 530.1 E(85289): 4.3e-150
Smith-Waterman score: 2734; 93.4% identity (93.4% similar) in 452 aa overlap (1-423:4-455)
10 20 30 40 50
pF1KE2 MATATRLLGCRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
10 20 30 40 50 60
60 70 80
pF1KE2 QEHLAPKAQEIDRSNEFKNLR-----------------------------EFWKQLGNLG
::::::::::::::::::::: ::::::::::
XP_016 QEHLAPKAQEIDRSNEFKNLRVSWEVRAVGGSQGVGLSCTAAWKSSHSFLEFWKQLGNLG
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE2 VLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE2 YLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVY
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE2 AKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE2 ENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMAD
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE2 MYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDF
370 380 390 400 410 420
390 400 410 420
pF1KE2 PMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH
:::::::::::::::::::::::::::::::::::
XP_016 PMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH
430 440 450
>>XP_006720558 (OMIM: 243500,607036) PREDICTED: isovaler (347 aa)
initn: 2089 init1: 2089 opt: 2089 Z-score: 2551.3 bits: 480.8 E(85289): 2.3e-135
Smith-Waterman score: 2089; 99.7% identity (99.7% similar) in 320 aa overlap (1-320:4-323)
10 20 30 40 50
pF1KE2 MATATRLLGCRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 QEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKAEKKGNHYILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 VLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDC
:::::::::::::::::::::::
XP_006 VLDHTIPYLHVREAFGQKIGHFQGRPFPPNTHLGGRARPEVRRPWSR
310 320 330 340
>>XP_016877638 (OMIM: 243500,607036) PREDICTED: isovaler (516 aa)
initn: 2016 init1: 2016 opt: 2023 Z-score: 2468.3 bits: 466.0 E(85289): 9.5e-131
Smith-Waterman score: 2450; 90.7% identity (91.4% similar) in 421 aa overlap (1-392:4-423)
10 20 30 40 50
pF1KE2 MATATRLLGCRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
10 20 30 40 50 60
60 70 80
pF1KE2 QEHLAPKAQEIDRSNEFKNLR-----------------------------EFWKQLGNLG
::::::::::::::::::::: ::::::::::
XP_016 QEHLAPKAQEIDRSNEFKNLRVSWEVRAVGGSQGVGLSCTAAWKSSHSFLEFWKQLGNLG
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE2 VLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE2 YLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVY
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE2 AKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE2 ENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMAD
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE2 MYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDF
:::::::::::::::::::::::::::::::::::::::::::::::::::: . . .
XP_016 MYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGQT-FSAQH
370 380 390 400 410
390 400 410 420
pF1KE2 PMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH
: ::
XP_016 PPGREGETRGQTSLEQVSTARELRCKILLPELTPRVLLPQLASWISDQKLPFLKILLCSP
420 430 440 450 460 470
>>XP_016877640 (OMIM: 243500,607036) PREDICTED: isovaler (476 aa)
initn: 2016 init1: 2016 opt: 2016 Z-score: 2460.3 bits: 464.4 E(85289): 2.7e-130
Smith-Waterman score: 2443; 92.7% identity (92.7% similar) in 409 aa overlap (1-380:4-412)
10 20 30 40 50
pF1KE2 MATATRLLGCRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAINGLSEEQRQLRQTMAKFL
10 20 30 40 50 60
60 70 80
pF1KE2 QEHLAPKAQEIDRSNEFKNLR-----------------------------EFWKQLGNLG
::::::::::::::::::::: ::::::::::
XP_016 QEHLAPKAQEIDRSNEFKNLRVSWEVRAVGGSQGVGLSCTAAWKSSHSFLEFWKQLGNLG
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE2 VLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEK
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE2 YLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNHYILNGNKFWITNGPDADVLIVY
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE2 AKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGH
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE2 ENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMAD
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE2 MYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGGNGYINDF
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYTRLMACRQYVYNVAKACDEGHCTAKDCAGVILYSAECATQVALDGIQCFGHAPQPFLY
370 380 390 400 410 420
390 400 410 420
pF1KE2 PMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFH
XP_016 TEPVNYQAPRKFFSGSQHLADLFRPTPTWEGGRDPRSDVPGAGEHCEGTEMQDPPA
430 440 450 460 470
423 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:05:47 2016 done: Mon Nov 7 01:05:49 2016
Total Scan time: 7.550 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]