Result of FASTA (omim) for
pF1KE2341
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2341, 736 aa
1>>>pF1KE2341 736 - 736 aa - 736 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0402+/-0.000457; mu= 21.3476+/- 0.028
mean_var=71.0243+/-14.100, 0's: 0 Z-trim(109.3): 150 B-trim: 141 in 1/55
Lambda= 0.152185
statistics sampled from 17329 (17485) to 17329 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.205), width: 16
Scan time: 11.550
The best scores are: opt bits E(85289)
NP_000405 (OMIM: 233400,261515,601860) peroxisomal ( 736) 4839 1072.6 0
NP_001186221 (OMIM: 233400,261515,601860) peroxiso ( 718) 4606 1021.4 0
NP_001278956 (OMIM: 233400,261515,601860) peroxiso ( 712) 4605 1021.2 0
NP_001186220 (OMIM: 233400,261515,601860) peroxiso ( 761) 4605 1021.2 0
NP_001278957 (OMIM: 233400,261515,601860) peroxiso ( 596) 3910 868.6 0
NP_055049 (OMIM: 601417) estradiol 17-beta-dehydro ( 261) 342 84.9 4.5e-16
NP_001007101 (OMIM: 184755,613724) non-specific li ( 140) 298 75.0 2.3e-13
XP_016857535 (OMIM: 184755,613724) PREDICTED: non- ( 143) 298 75.1 2.3e-13
NP_001007100 (OMIM: 184755,613724) non-specific li ( 143) 298 75.1 2.3e-13
NP_001180546 (OMIM: 184755,613724) non-specific li ( 466) 302 76.3 3.1e-13
NP_001180529 (OMIM: 184755,613724) non-specific li ( 503) 302 76.4 3.3e-13
NP_001180528 (OMIM: 184755,613724) non-specific li ( 523) 302 76.4 3.4e-13
NP_002970 (OMIM: 184755,613724) non-specific lipid ( 547) 302 76.4 3.5e-13
NP_620419 (OMIM: 608989) epidermal retinol dehydro ( 309) 266 68.3 5.4e-11
NP_001304978 (OMIM: 608989) epidermal retinol dehy ( 318) 266 68.3 5.5e-11
XP_005266734 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 298) 264 67.8 7.1e-11
NP_002026 (OMIM: 136440) 3-ketodihydrosphingosine ( 332) 264 67.9 7.7e-11
NP_066284 (OMIM: 611596) dehydrogenase/reductase S ( 278) 250 64.7 5.7e-10
NP_060911 (OMIM: 605843) peroxisomal trans-2-enoyl ( 303) 247 64.1 9.6e-10
NP_004744 (OMIM: 612830) short-chain dehydrogenase ( 302) 225 59.3 2.7e-08
NP_932349 (OMIM: 615196) dehydrogenase/reductase S ( 232) 223 58.7 3e-08
NP_835236 (OMIM: 612127) 17-beta-hydroxysteroid de ( 300) 219 58.0 6.7e-08
XP_016881179 (OMIM: 136440) PREDICTED: 3-ketodihyd ( 255) 218 57.7 6.9e-08
NP_001317088 (OMIM: 616160) dehydrogenase/reductas ( 310) 204 54.7 6.8e-07
NP_056325 (OMIM: 616160) dehydrogenase/reductase S ( 325) 204 54.7 7e-07
XP_016879915 (OMIM: 616160) PREDICTED: dehydrogena ( 325) 204 54.7 7e-07
XP_011522088 (OMIM: 616160) PREDICTED: dehydrogena ( 334) 204 54.7 7.2e-07
XP_016879914 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 204 54.7 7.8e-07
XP_005256652 (OMIM: 616160) PREDICTED: dehydrogena ( 372) 204 54.7 7.8e-07
XP_006720064 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 201 54.0 9.9e-07
NP_005785 (OMIM: 615194) dehydrogenase/reductase S ( 280) 201 54.0 9.9e-07
XP_005267306 (OMIM: 615194) PREDICTED: dehydrogena ( 280) 201 54.0 9.9e-07
NP_878912 (OMIM: 615194) dehydrogenase/reductase S ( 300) 201 54.0 1e-06
NP_057329 (OMIM: 612831) estradiol 17-beta-dehydro ( 300) 201 54.0 1e-06
XP_011516920 (OMIM: 264300,605573) PREDICTED: test ( 310) 201 54.0 1.1e-06
XP_011516921 (OMIM: 264300,605573) PREDICTED: test ( 310) 201 54.0 1.1e-06
XP_016870160 (OMIM: 264300,605573) PREDICTED: test ( 310) 201 54.0 1.1e-06
NP_000188 (OMIM: 264300,605573) testosterone 17-be ( 310) 201 54.0 1.1e-06
XP_016870161 (OMIM: 264300,605573) PREDICTED: test ( 310) 201 54.0 1.1e-06
NP_065715 (OMIM: 615839) peroxisomal 2,4-dienoyl-C ( 292) 197 53.1 1.9e-06
NP_001309209 (OMIM: 612833) dehydrogenase/reductas ( 289) 194 52.5 2.9e-06
NP_057113 (OMIM: 612833) dehydrogenase/reductase S ( 339) 194 52.5 3.3e-06
NP_001099041 (OMIM: 616161) dehydrogenase/reductas ( 311) 193 52.3 3.6e-06
XP_016876857 (OMIM: 612833) PREDICTED: dehydrogena ( 404) 194 52.6 3.8e-06
NP_004484 (OMIM: 300220,300256,300438) 3-hydroxyac ( 261) 190 51.5 5e-06
NP_056540 (OMIM: 608575) retinol dehydrogenase 8 [ ( 331) 190 51.6 6e-06
NP_001207422 (OMIM: 616161) dehydrogenase/reductas ( 312) 187 50.9 9e-06
XP_016868637 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326) 186 50.7 1.1e-05
XP_016868636 (OMIM: 222745) PREDICTED: 2,4-dienoyl ( 326) 186 50.7 1.1e-05
NP_001317504 (OMIM: 222745) 2,4-dienoyl-CoA reduct ( 326) 186 50.7 1.1e-05
>>NP_000405 (OMIM: 233400,261515,601860) peroxisomal mul (736 aa)
initn: 4839 init1: 4839 opt: 4839 Z-score: 5739.4 bits: 1072.6 E(85289): 0
Smith-Waterman score: 4839; 100.0% identity (100.0% similar) in 736 aa overlap (1-736:1-736)
10 20 30 40 50 60
pF1KE2 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
670 680 690 700 710 720
730
pF1KE2 MLSQKLQMILKDYAKL
::::::::::::::::
NP_000 MLSQKLQMILKDYAKL
730
>>NP_001186221 (OMIM: 233400,261515,601860) peroxisomal (718 aa)
initn: 4715 init1: 4605 opt: 4606 Z-score: 5463.1 bits: 1021.4 E(85289): 0
Smith-Waterman score: 4683; 97.6% identity (97.6% similar) in 736 aa overlap (1-736:1-718)
10 20 30 40 50 60
pF1KE2 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
::::::::::::::::::: :::::::::::::::::::::::
NP_001 MGSPLRFDGRVVLVTGAGA------------------VNDLGGDFKGVGKGSLAADKVVE
10 20 30 40
70 80 90 100 110 120
pF1KE2 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE2 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE2 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE2 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE2 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE2 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
650 660 670 680 690 700
730
pF1KE2 MLSQKLQMILKDYAKL
::::::::::::::::
NP_001 MLSQKLQMILKDYAKL
710
>>NP_001278956 (OMIM: 233400,261515,601860) peroxisomal (712 aa)
initn: 4605 init1: 4605 opt: 4605 Z-score: 5461.9 bits: 1021.2 E(85289): 0
Smith-Waterman score: 4605; 99.6% identity (99.9% similar) in 702 aa overlap (35-736:11-712)
10 20 30 40 50 60
pF1KE2 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR
.: .::::::::::::::::::::::::::
NP_001 MEKIISQCRFFVSMNDLGGDFKGVGKGSLAADKVVEEIRR
10 20 30 40
70 80 90 100 110 120
pF1KE2 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 GKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 EGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFI
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE2 YEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLK
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE2 CEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAI
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRV
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE2 LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVD
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE2 LAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKW
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE2 TIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQ
650 660 670 680 690 700
730
pF1KE2 KLQMILKDYAKL
::::::::::::
NP_001 KLQMILKDYAKL
710
>>NP_001186220 (OMIM: 233400,261515,601860) peroxisomal (761 aa)
initn: 4605 init1: 4605 opt: 4605 Z-score: 5461.5 bits: 1021.2 E(85289): 0
Smith-Waterman score: 4605; 99.6% identity (99.9% similar) in 702 aa overlap (35-736:60-761)
10 20 30 40 50 60
pF1KE2 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR
.: .::::::::::::::::::::::::::
NP_001 PGFCRKRSVSCCFQNLCNNPMEKIISQCRFFVSMNDLGGDFKGVGKGSLAADKVVEEIRR
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE2 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE2 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE2 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE2 GKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDS
270 280 290 300 310 320
310 320 330 340 350 360
pF1KE2 EGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFI
330 340 350 360 370 380
370 380 390 400 410 420
pF1KE2 YEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLK
390 400 410 420 430 440
430 440 450 460 470 480
pF1KE2 CEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAI
450 460 470 480 490 500
490 500 510 520 530 540
pF1KE2 PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRV
510 520 530 540 550 560
550 560 570 580 590 600
pF1KE2 LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVD
570 580 590 600 610 620
610 620 630 640 650 660
pF1KE2 LAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKW
630 640 650 660 670 680
670 680 690 700 710 720
pF1KE2 TIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQ
690 700 710 720 730 740
730
pF1KE2 KLQMILKDYAKL
::::::::::::
NP_001 KLQMILKDYAKL
750 760
>>NP_001278957 (OMIM: 233400,261515,601860) peroxisomal (596 aa)
initn: 3899 init1: 3899 opt: 3910 Z-score: 4638.3 bits: 868.6 E(85289): 0
Smith-Waterman score: 3910; 99.5% identity (99.5% similar) in 599 aa overlap (138-736:1-596)
110 120 130 140 150 160
pF1KE2 FARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAA
::::: ::::::::::::::::::::::
NP_001 MKKQK---IIMTSSASGIYGNFGQANYSAA
10 20
170 180 190 200 210 220
pF1KE2 KLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCH
30 40 50 60 70 80
230 240 250 260 270 280
pF1KE2 ESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQS
90 100 110 120 130 140
290 300 310 320 330 340
pF1KE2 IQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMY
150 160 170 180 190 200
350 360 370 380 390 400
pF1KE2 ALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHG
210 220 230 240 250 260
410 420 430 440 450 460
pF1KE2 EQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSG
270 280 290 300 310 320
470 480 490 500 510 520
pF1KE2 GFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFD
330 340 350 360 370 380
530 540 550 560 570 580
pF1KE2 KPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQ
390 400 410 420 430 440
590 600 610 620 630 640
pF1KE2 TKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVN
450 460 470 480 490 500
650 660 670 680 690 700
pF1KE2 AVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQK
510 520 530 540 550 560
710 720 730
pF1KE2 AFFSGRLKARGNIMLSQKLQMILKDYAKL
:::::::::::::::::::::::::::::
NP_001 AFFSGRLKARGNIMLSQKLQMILKDYAKL
570 580 590
>>NP_055049 (OMIM: 601417) estradiol 17-beta-dehydrogena (261 aa)
initn: 365 init1: 145 opt: 342 Z-score: 409.6 bits: 84.9 E(85289): 4.5e-16
Smith-Waterman score: 357; 35.0% identity (61.6% similar) in 263 aa overlap (1-237:1-260)
10 20 30 40 50
pF1KE2 MGSPL--RFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKG-SLAADK
:.: : :. . ..::::::.:.::: .. .: .:: :.. :: : .. . : .
NP_055 MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDL--DRAAAQETVRLLGGP
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 VVEEIRRRGGKAVANYDSVE-EGEKVVKTALDA-FGRI-DVVVNNAGILRDRSFARISDE
.: ::..:. . : : .. . . ..: :.: .:::. ::: .:. . ..:..
NP_055 GSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSED
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 DWDIIHRVHLRGSFQVTRAAWEHMKKQK-YGRIIMTSSASGIYGNFGQANYSAAKLGLLG
::: . :.:.:.: ::.:: . . .. : :: :: : :: ::.::.:.: :..:
NP_055 DWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIG
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 LANSLAIEGRKSNIHCNTIAPN-AGSRMTQTVMPEDLVEALK----------PEYVAPLV
:... : : . .:.::.. :. .. ::: : :. .:. . :: :: .:
NP_055 LTQTAARELGRHGIRCNSVLPGFIATPMTQKV-PQKVVDKITEMIPMGHLGDPEDVADVV
180 190 200 210 220 230
230 240 250 260 270
pF1KE2 LWLCHE--------SCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWK
.: : : : .::::
NP_055 AFLASEDSGYITGTSVEVTGGLFM
240 250 260
>>NP_001007101 (OMIM: 184755,613724) non-specific lipid- (140 aa)
initn: 220 init1: 220 opt: 298 Z-score: 361.1 bits: 75.0 E(85289): 2.3e-13
Smith-Waterman score: 298; 38.1% identity (73.0% similar) in 126 aa overlap (603-727:12-129)
580 590 600 610 620 630
pF1KE2 LQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIG
.. .::: . :.: .....::.::
NP_001 MGFPEAARTHQIEAVPTS-----SASDG--FKANLVFKEIE
10 20 30
640 650 660 670 680 690
pF1KE2 RRLKDIGPEVVKKVNAVFEWHITKG-GNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILS
..:.. : . :::....: ... : :. : :..:.:.:.:.: . : :: :: ..
NP_001 KKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDK-KADCTITMA
40 50 60 70 80 90
700 710 720 730
pF1KE2 DEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
: ::. .. ::..::.:::.:.:: ::. :..:::
NP_001 DSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNLQLQPGNAKL
100 110 120 130 140
>>XP_016857535 (OMIM: 184755,613724) PREDICTED: non-spec (143 aa)
initn: 220 init1: 220 opt: 298 Z-score: 360.9 bits: 75.1 E(85289): 2.3e-13
Smith-Waterman score: 298; 38.1% identity (73.0% similar) in 126 aa overlap (603-727:15-132)
580 590 600 610 620 630
pF1KE2 LQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIG
.. .::: . :.: .....::.::
XP_016 MGFPEAASSFRTHQIEAVPTS-----SASDG--FKANLVFKEIE
10 20 30
640 650 660 670 680 690
pF1KE2 RRLKDIGPEVVKKVNAVFEWHITKG-GNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILS
..:.. : . :::....: ... : :. : :..:.:.:.:.: . : :: :: ..
XP_016 KKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDK-KADCTITMA
40 50 60 70 80 90
700 710 720 730
pF1KE2 DEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
: ::. .. ::..::.:::.:.:: ::. :..:::
XP_016 DSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNLQLQPGNAKL
100 110 120 130 140
>>NP_001007100 (OMIM: 184755,613724) non-specific lipid- (143 aa)
initn: 220 init1: 220 opt: 298 Z-score: 360.9 bits: 75.1 E(85289): 2.3e-13
Smith-Waterman score: 298; 38.1% identity (73.0% similar) in 126 aa overlap (603-727:15-132)
580 590 600 610 620 630
pF1KE2 LQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIG
.. .::: . :.: .....::.::
NP_001 MGFPEAASSFRTHQIEAVPTS-----SASDG--FKANLVFKEIE
10 20 30
640 650 660 670 680 690
pF1KE2 RRLKDIGPEVVKKVNAVFEWHITKG-GNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILS
..:.. : . :::....: ... : :. : :..:.:.:.:.: . : :: :: ..
NP_001 KKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDK-KADCTITMA
40 50 60 70 80 90
700 710 720 730
pF1KE2 DEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
: ::. .. ::..::.:::.:.:: ::. :..:::
NP_001 DSDFLALMTGKMNPQSAFFQGKLKITGNMGLAMKLQNLQLQPGNAKL
100 110 120 130 140
>>NP_001180546 (OMIM: 184755,613724) non-specific lipid- (466 aa)
initn: 220 init1: 220 opt: 302 Z-score: 358.6 bits: 76.3 E(85289): 3.1e-13
Smith-Waterman score: 302; 32.7% identity (69.2% similar) in 156 aa overlap (581-727:302-455)
560 570 580 590 600 610
pF1KE2 NDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSG
: .. .: .. : .:.. . . : ..
NP_001 KGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGF-PEAA
280 290 300 310 320 330
620 630 640 650 660
pF1KE2 TSAKT------PSEGGK--LQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKG-GNIG
.: .: :. ... .....::.:: ..:.. : . :::....: ... : :.
NP_001 SSFRTHQIEAVPTSSASDGFKANLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKE
340 350 360 370 380 390
670 680 690 700 710 720
pF1KE2 AKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIM
: :..:.:.:.:.: . : :: :: ..: ::. .. ::..::.:::.:.:: ::.
NP_001 ATWVVDVKNGKGSVLPNSDK-KADCTITMADSDFLALMTGKMNPQSAFFQGKLKITGNMG
400 410 420 430 440
730
pF1KE2 LSQKLQMILKDYAKL
:..:::
NP_001 LAMKLQNLQLQPGNAKL
450 460
736 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:32:48 2016 done: Mon Nov 7 02:32:50 2016
Total Scan time: 11.550 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]